Simon Conway

  • 17303 Citations
  • 64 h-Index
1994 …2020

Research output per year

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Publications

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A bHLH code for cardiac morphogenesis

Conway, S. J., Firulli, B. & Firulli, A. B., 2010, In : Pediatric Cardiology. 31, 3, p. 318-324 7 p.

Research output: Contribution to journalArticle

18 Scopus citations
33 Scopus citations

Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages

Hoeffel, G., Wang, Y., Greter, M., See, P., Teo, P., Malleret, B., Leboeuf, M., Low, D., Oller, G., Almeida, F., Choy, S. H. Y., Grisotto, M., Renia, L., Conway, S. J., Stanley, E. R., Chan, J. K. Y., Ng, L. G., Samokhvalov, I. M., Merad, M. & Ginhoux, F., Jun 4 2012, In : Journal of Experimental Medicine. 209, 6, p. 1167-1181 15 p.

Research output: Contribution to journalArticle

420 Scopus citations

Adult satellite cells and embryonic muscle progenitors have distinct genetic requirements

Lepper, C., Conway, S. J. & Fan, C. M., Jul 30 2009, In : Nature. 460, 7255, p. 627-631 5 p.

Research output: Contribution to journalArticle

357 Scopus citations

Alk3/Bmpr1a receptor is required for development of the atrioventricular canal into valves and annulus fibrosus

Gaussin, V., Morley, G. E., Cox, L., Zwijsen, A., Vance, K. M., Emile, L., Tian, Y., Liu, J., Hong, C., Myers, D., Conway, S. J., Depre, C., Mishina, Y., Behringer, R. R., Hanks, M. C., Schneider, M. D., Huylebroeck, D., Fishman, G. I., Burch, J. B. E. & Vatner, S. F., Aug 5 2005, In : Circulation research. 97, 3, p. 219-226 8 p.

Research output: Contribution to journalArticle

107 Scopus citations

All primitive and definitive hematopoietic progenitor cells emerging before E10 in the mouse embryo are products of the yolk sac

Lux, C. T., Yoshimoto, M., McGrath, K., Conway, S. J., Palis, J. & Yoder, M. C., Apr 1 2008, In : Blood. 111, 7, p. 3435-3438 4 p.

Research output: Contribution to journalArticle

190 Scopus citations

Altered Twist1 and Hand2 dimerization is associated with Saethre-Chotzen syndrome and limb abnormalities

Firulli, B. A., Krawchuk, D., Centonze, V. E., Vargesson, N., Virshup, D. M., Conway, S. J., Cserjesi, P., Laufer, E. & Firulli, A. B., Apr 1 2005, In : Nature genetics. 37, 4, p. 373-381 9 p.

Research output: Contribution to journalArticle

129 Scopus citations

A murine model of neurofibromatosis type 2 that accurately phenocopies human schwannoma formation

Gehlhausen, J. R., Park, S. J., Hickox, A. E., Shew, M., Staser, K., Rhodes, S. D., Menon, K., Lajiness, J. D., Mwanthi, M., Yang, X., Yuan, J., Territo, P., Hutchins, G., Nalepa, G., Yang, F-C., Conway, S. J., Heinz, M. G., Stemmer-Rachamimov, A., Yates, C. W. & Clapp, D. W., Jan 1 2015, In : Human molecular genetics. 24, 1, p. 1-8 8 p., ddu414.

Research output: Contribution to journalArticle

31 Scopus citations

An absence of Twist1 results in aberrant cardiac neural crest morphogenesis

Vincentz, J. W., Barnes, R. M., Rodgers, R., Firulli, B. A., Conway, S. J. & Firulli, A. B., Aug 1 2008, In : Developmental Biology. 320, 1, p. 131-139 9 p.

Research output: Contribution to journalArticle

50 Scopus citations

Analysis of expression of the microphthalmia gene in vitiligo (miut /miut) mutant mice

Bora, N. & Conway, S., Dec 1 1997, In : Investigative Ophthalmology and Visual Science. 38, 4, p. S325

Research output: Contribution to journalArticle

Analysis of the Hand1 cell lineage reveals novel contributions to cardiovascular, neural crest, extra-embryonic, and lateral mesoderm derivatives

Barnes, R. M., Firulli, B. A., Conway, S. J., Vincentz, J. W. & Firulli, A. B., Nov 2010, In : Developmental Dynamics. 239, 11, p. 3086-3097 12 p.

Research output: Contribution to journalArticle

35 Scopus citations

A protective role for periostin and TGF-β in IgE-mediated allergy and airway hyperresponsiveness

Gordon, E. D., Sidhu, S. S., Wang, Z. E., Woodruff, P. G., Yuan, S., Solon, M. C., Conway, S. J., Huang, X., Locksley, R. M. & Fahy, J. V., Jan 2012, In : Clinical and Experimental Allergy. 42, 1, p. 144-155 12 p.

Research output: Contribution to journalArticle

66 Scopus citations

Armadillo-like helical domain containing-4 is dynamically expressed in both the first and second heart fields

Conway, S. J., McConnell, R., Simmons, O. & Snider, P. L., Dec 2019, In : Gene Expression Patterns. 34, 119077.

Research output: Contribution to journalArticle

9 Scopus citations

Ataxia telangiectasia mutated in cardiac fibroblasts regulates doxorubicin-induced cardiotoxicity

Zhan, H., Aizawa, K., Sun, J., Tomida, S., Otsu, K., Conway, S. J., McKinnon, P. J., Manabe, I., Komuro, I., Miyagawa, K., Nagai, R. & Suzuki, T., May 1 2016, In : Cardiovascular research. 110, 1, p. 85-95 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

Autonomous murine T-cell progenitor production in the extra-embryonic yolk sac before HSC emergence

Yoshimoto, M., Porayette, P., Glosson, N. L., Conway, S. J., Carlesso, N., Cardoso, A. A., Kaplan, M. H. & Yoder, M. C., Jun 14 2012, In : Blood. 119, 24, p. 5706-5714 9 p.

Research output: Contribution to journalArticle

80 Scopus citations

BMP10 is essential for maintaining cardiac growth during murine cardiogenesis

Chen, H., Shi, S., Acosta, L., Li, W., Lu, J., Bao, S., Chen, Z., Yang, Z., Schneider, M. D., Chien, K. R., Conway, S. J., Yoder, M. C., Haneline, L. S., Franco, D. & Shou, W., May 1 2004, In : Development. 131, 9, p. 2219-2231 13 p.

Research output: Contribution to journalArticle

314 Scopus citations

Bone Morphogenetic Protein Signaling Is Required for Aortic Valve Calcification

Gomez-Stallons, M. V., Wirrig-Schwendeman, E. E., Hassel, K. R., Conway, S. J. & Yutzey, K. E., Jul 1 2016, In : Arteriosclerosis, thrombosis, and vascular biology. 36, 7, p. 1398-1405 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Cardiac fibroblasts are essential for the adaptive response of the murine heart to pressure overload

Takeda, N., Manabe, I., Uchino, Y., Eguchi, K., Matsumoto, S., Nishimura, S., Shindo, T., Sano, M., Otsu, K., Snider, P., Conway, S. J. & Nagai, R., Jan 4 2010, In : Journal of Clinical Investigation. 120, 1, p. 254-265 12 p.

Research output: Contribution to journalArticle

244 Scopus citations

Cardiac-specific expression and hypertrophic upregulation of the feline Na+-Ca2+ exchanger gene H1-promoter in a transgenic mouse model

Müller, J. G., Isomatsu, Y., Koushik, S. V., O'Quinn, M., Xu, L., Kappler, C. S., Hapke, E., Zile, M. R., Conway, S. J. & Menick, D. R., Feb 8 2002, In : Circulation research. 90, 2, p. 158-164 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Cardiogenic genes expressed in cardiac fibroblasts contribute to heart development and repair

Furtado, M. B., Costa, M. W., Pranoto, E. A., Salimova, E., Pinto, A. R., Lam, N. T., Park, A., Snider, P., Chandran, A., Harvey, R. P., Boyd, R., Conway, S. J., Pearson, J., Kaye, D. M. & Rosenthal, N. A., Apr 25 2014, In : Circulation research. 114, 9, p. 1422-1434 13 p.

Research output: Contribution to journalArticle

114 Scopus citations

Cardiovascular defects associated with abnormalities in midline development in the Loop-tail mouse mutant

Henderson, D. J., Conway, S. J., Greene, N. D. E., Gerrelli, D., Murdoch, J. N., Anderson, R. H. & Copp, A. J., Jul 6 2001, In : Circulation research. 89, 1, p. 6-12 7 p.

Research output: Contribution to journalArticle

Open Access
59 Scopus citations

Characterization of Pax3-expressing cells from adult blood vessels

Goupille, O., Pallafacchina, G., Relaix, F., Conway, S. J., Cumano, A., Robert, B., Montarras, D. & Buckingham, M., Dec 2011, In : Journal of cell science. 124, 23, p. 3980-3988 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Chemopreventative celecoxib fails to prevent schwannoma formation or sensorineural hearing loss in genetically engineered murine model of neurofibromatosis type 2

Wahle, B. M., Hawley, E. T., He, Y., Smith, A. E., Yuan, J., Masters, A. R., Jones, D. R., Gehlhausen, J. R., Park, S. J., Conway, S. J., Clapp, D. W. & Yates, C. W., 2018, In : Oncotarget. 9, 1, p. 718-725 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Chronic administration of KB-R7943 induces up-regulation of cardiac NCX1

Xu, L., Kappler, C. S., Mani, S. K., Shepherd, N. R., Renaud, L., Snider, P., Conway, S. J. & Menick, D. R., Oct 2 2009, In : Journal of Biological Chemistry. 284, 40, p. 27265-27272 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Comparison of the four mouse fasciclin-containing genes expression patterns during valvuloseptal morphogenesis

Lindsley, A., Li, W., Wang, J., Maeda, N., Rogers, R. & Conway, S. J., Jun 1 2005, In : Gene Expression Patterns. 5, 5, p. 593-600 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

Constitutive overexpression of periostin delays wound healing in mouse skin

Nunomura, S., Nanri, Y., Ogawa, M., Arima, K., Mitamura, Y., Yoshihara, T., Hasuwa, H., Conway, S. J. & Izuhara, K., Jan 1 2018, In : Wound Repair and Regeneration. 26, 1, p. 6-15 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Cooperative interaction of Nkx2.5 and Mef2c transcription factors during heart development

Vincentz, J. W., Barnes, R. M., Firulli, B. A., Conway, S. J. & Firulli, A. B., Dec 2008, In : Developmental Dynamics. 237, 12, p. 3809-3819 11 p.

Research output: Contribution to journalArticle

52 Scopus citations

Cross-talk between transforming growth factor-b and periostin can be targeted for pulmonary fibrosis

Nanri, Y., Nunomura, S., Terasaki, Y., Yoshihara, T., Hirano, Y., Yokosaki, Y., Yamaguchi, Y., Feghali-Bostwick, C., Ajito, K., Murakami, S., Conway, S. J. & Izuhara, K., 2020, In : American journal of respiratory cell and molecular biology. 62, 2, p. 204-216 13 p.

Research output: Contribution to journalArticle

2 Scopus citations

Cyp1b1 mediates periostin regulation of trabecular meshwork development by suppression of oxidative stress

Zhao, Y., Wang, S., Sorenson, C. M., Teixeira, L., Dubielzig, R. R., Peters, D. M., Conway, S. J., Jefcoate, C. R. & Sheibani, N., 2013, In : Molecular and cellular biology. 33, 21, p. 4225-4240 16 p.

Research output: Contribution to journalArticle

Open Access
34 Scopus citations

Decreased neural crest stem cell expansion is responsible for the conotruncal heart defects within the Splotch (Sp(2H))/Pax3 mouse mutant

Conway, S. J., Bundy, J., Chen, J., Dickman, E., Rogers, R. & Will, B. M., Aug 1 2000, In : Cardiovascular research. 47, 2, p. 314-328 15 p.

Research output: Contribution to journalArticle

87 Scopus citations

Definitive Hematopoiesis in the Yolk Sac Emerges from Wnt-Responsive Hemogenic Endothelium Independently of Circulation and Arterial Identity

Frame, J. M., Fegan, K. H., Conway, S. J., McGrath, K. E. & Palis, J., Feb 1 2016, In : STEM CELLS. 34, 2, p. 431-444 14 p.

Research output: Contribution to journalArticle

62 Scopus citations

Development of a lethal congenital heart defect in the splotch (Pax3) mutant mouse

Conway, S. J., Henderson, D. J., Kirby, M. L., Anderson, R. H. & Copp, A. J., Nov 1 1997, In : Cardiovascular research. 36, 2, p. 163-173 11 p.

Research output: Contribution to journalArticle

108 Scopus citations

Differential influence of the 4F2 heavy chain and the protein related to b0,+ amino acid transport on substrate affinity of the heteromeric b0,+ amino acid transporter

Rajan, D. P., Huang, W., Kekuda, R., George, R. L., Wang, J., Conway, S. J., Devoe, L. D., Leibach, F. H., Prasad, P. D. & Ganapathy, V., May 12 2000, In : Journal of Biological Chemistry. 275, 19, p. 14331-14335 5 p.

Research output: Contribution to journalArticle

44 Scopus citations

Distinct roles of myofibroblast-specific Smad2 and Smad3 signaling in repair and remodeling of the infarcted heart

Huang, S., Chen, B., Su, Y., Alex, L., Humeres, C., Shinde, A. V., Conway, S. J. & Frangogiannis, N. G., Jul 2019, In : Journal of Molecular and Cellular Cardiology. 132, p. 84-97 14 p.

Research output: Contribution to journalArticle

9 Scopus citations

Distinct Sources of Hematopoietic Progenitors Emerge before HSCs and Provide Functional Blood Cells in the Mammalian Embryo

McGrath, K. E., Frame, J. M., Fegan, K. H., Bowen, J. R., Conway, S. J., Catherman, S. C., Kingsley, P. D., Koniski, A. D. & Palis, J., Jun 30 2015, In : Cell Reports. 11, 12, p. 1892-1904 13 p.

Research output: Contribution to journalArticle

128 Scopus citations

Distinct spatial and temporal distributions of aggrecan and versican in the embryonic chick heart

Zanin, M. K. B., Bundy, J., Ernst, H., Wessels, A., Conway, S. J. & Hoffman, S., Dec 1 1999, In : Anatomical Record. 256, 4, p. 366-380 15 p.

Research output: Contribution to journalArticle

39 Scopus citations

Electrical coupling between ventricular myocytes and myofibroblasts in the infarcted mouse heart

Rubart, M., Tao, W., Lu, X. L., Conway, S. J., Reuter, S. P., Lin, S. F. & Soonpaa, M. H., Mar 1 2018, In : Cardiovascular research. 114, 3, p. 389-400 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

Embryonic day 9 yolk sac and intra-embryonic hemogenic endothelium independently generate a B-1 and marginal zone progenitor lacking B-2 potential

Yoshimoto, M., Montecino-Rodriguez, E., Ferkowicz, M. J., Porayette, P., Shelley, W. C., Conway, S. J., Dorshkind, K. & Yoder, M. C., Jan 25 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 4, p. 1468-1473 6 p.

Research output: Contribution to journalArticle

149 Scopus citations

Expression of folate receptor α in the mammalian retinol pigmented epithelium and retina

Smith, S. B., Kekuda, R., Gu, X., Chancy, C., Conway, S. J. & Ganapathy, V., Apr 13 1999, In : Investigative Ophthalmology and Visual Science. 40, 5, p. 840-848 9 p.

Research output: Contribution to journalArticle

37 Scopus citations

Expression pattern of the type 1 sigma receptor in the brain and identity of critical anionic amino acid residues in the ligand-binding domain of the receptor

Seth, P., Ganapathy, M. E., Conway, S. J., Bridges, C. D., Smith, S. B., Casellas, P. & Ganapathy, V., Jul 25 2001, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1540, 1, p. 59-67 9 p.

Research output: Contribution to journalArticle

70 Scopus citations

Fate mapping analysis reveals that adult microglia derive from primitive macrophages

Ginhoux, F., Greter, M., Leboeuf, M., Nandi, S., See, P., Gokhan, S., Mehler, M. F., Conway, S. J., Ng, L. G., Stanley, E. R., Samokhvalov, I. M. & Merad, M., Nov 5 2010, In : Science. 330, 6005, p. 841-845 5 p.

Research output: Contribution to journalArticle

2184 Scopus citations

Fibroblast Primary Cilia Are Required for Cardiac Fibrosis

Villalobos, E., Criollo, A., Schiattarella, G. G., Altamirano, F., French, K. M., May, H. I., Jiang, N., Nguyen, N. U. N., Romero, D., Roa, J. C., García, L., Diaz-Araya, G., Morselli, E., Ferdous, A., Conway, S. J., Sadek, H. A., Gillette, T. G., Lavandero, S. & Hill, J. A., May 14 2019, In : Circulation. 139, 20, p. 2342-2357 16 p.

Research output: Contribution to journalArticle

15 Scopus citations

Fkbp1a controls ventricular myocardium trabeculation and compaction by regulating endocardial Notch1 activity

Chen, H., Zhang, W., Sun, X., Yoshimoto, M., Chen, Z., Zhu, W., Liu, J., Shen, Y., Yong, W., Li, D., Zhang, J., Lin, Y., Li, B., VanDusen, N. J., Snider, P., Schwartz, R. J., Conway, S. J., Field, L. J., Yoder, M. C., Firulli, A. B. & 3 others, Carlesso, N., Towbin, J. A. & Shou, W., May 1 2013, In : Development (Cambridge). 140, 9, p. 1946-1957 12 p.

Research output: Contribution to journalArticle

46 Scopus citations

Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter

Wu, X., Huang, W., Prasad, P. D., Seth, P., Rajan, D. P., Leibach, F. H., Chen, J., Conway, S. J. & Ganapathy, V., Sep 1999, In : Journal of Pharmacology and Experimental Therapeutics. 290, 3, p. 1482-1492 11 p.

Research output: Contribution to journalArticle

292 Scopus citations

Functional Characteristics of NaS2, a Placenta-specific Na+-coupled Transporter for Sulfate and Oxyanions of the Micronutrients Selenium and Chromium

Miyauchi, S., Srinivas, S. R., Fei, Y. J., Gopal, E., Umapathy, N. S., Wang, H., Conway, S. J., Ganapathy, V. & Prasad, P. D., Jun 1 2006, In : Placenta. 27, 6-7, p. 550-559 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Generation and characterization of Csrp1 enhancer-driven tissue-restricted Cre-recombinase mice

Snider, P., Fix, J. L., Rogers, R., Peabody-Dowling, G., Ingram, D., Lilly, B. & Conway, S. J., Mar 2008, In : Genesis. 46, 3, p. 167-176 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Generation of a conditional loxP allele of the Pax3 transcription factor that enables selective deletion of the homeodomain

Koushik, S. V., Chen, H., Wang, J. & Conway, S. J., 2002, In : Genesis. 32, 2, p. 114-117 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Generation of Smad7-Cre recombinase mice: A useful tool for the study of epithelial-mesenchymal transformation within the embryonic heart

Snider, P., Tang, S., Lin, G., Wang, J. & Conway, S. J., 2009, In : Genesis. 47, 7, p. 469-475 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Generation of transgenic mice that conditionally express microRNA miR-145

Sawant, D., Klevenow, E., Baeten, J. T., Thomas, S., Manivannan, S., Conway, S. J. & Lilly, B., 2020, (Accepted/In press) In : Genesis.

Research output: Contribution to journalArticle