Simon Conway

  • 17303 Citations
  • 64 h-Index
1994 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Publications

Filter
Article
2014

SHP-2 deletion in postmigratory neural crest cells results in impaired cardiac sympathetic innervation

Lajiness, J. D., Snider, P., Wang, J., Feng, G. S., Krenz, M. & Conway, S. J., 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 14, p. E1374-E1382

Research output: Contribution to journalArticle

7 Scopus citations
2013

Cyp1b1 mediates periostin regulation of trabecular meshwork development by suppression of oxidative stress

Zhao, Y., Wang, S., Sorenson, C. M., Teixeira, L., Dubielzig, R. R., Peters, D. M., Conway, S. J., Jefcoate, C. R. & Sheibani, N., 2013, In : Molecular and cellular biology. 33, 21, p. 4225-4240 16 p.

Research output: Contribution to journalArticle

Open Access
34 Scopus citations

Fkbp1a controls ventricular myocardium trabeculation and compaction by regulating endocardial Notch1 activity

Chen, H., Zhang, W., Sun, X., Yoshimoto, M., Chen, Z., Zhu, W., Liu, J., Shen, Y., Yong, W., Li, D., Zhang, J., Lin, Y., Li, B., VanDusen, N. J., Snider, P., Schwartz, R. J., Conway, S. J., Field, L. J., Yoder, M. C., Firulli, A. B. & 3 others, Carlesso, N., Towbin, J. A. & Shou, W., May 1 2013, In : Development (Cambridge). 140, 9, p. 1946-1957 12 p.

Research output: Contribution to journalArticle

46 Scopus citations

Haemogenic endocardium contributes to transient definitive haematopoiesis

Nakano, H., Liu, X., Arshi, A., Nakashima, Y., Van Handel, B., Sasidharan, R., Harmon, A. W., Shin, J. H., Schwartz, R. J., Conway, S. J., Harvey, R. P., Pashmforoush, M., Mikkola, H. K. A. & Nakano, A., Apr 11 2013, In : Nature communications. 4, 1564.

Research output: Contribution to journalArticle

76 Scopus citations

Heterozygous inactivation of the NF1 gene in myeloid cells enhances neointima formation via a rosuvastatin-sensitive cellular pathway

Stansfield, B. K., Bessler, W. K., Mali, R., Mund, J. A., Downing, B., Li, F., Sarchet, K. N., DiStasi, M. R., Conway, S. J., Kapur, R. & Ingram, D. A., Mar 1 2013, In : Human molecular genetics. 22, 5, p. 977-988 12 p., dds502.

Research output: Contribution to journalArticle

11 Scopus citations

Periostin Deficiency Increases Bone Damage and Impairs Injury Response to Fatigue Loading in Adult Mice

Bonnet, N., Gineyts, E., Ammann, P., Conway, S. J., Garnero, P. & Ferrari, S., Oct 22 2013, In : PloS one. 8, 10, e78347.

Research output: Contribution to journalArticle

29 Scopus citations

Periostin downregulation is an early marker of inhibited neonatal murine lung alveolar septation

Ahlfeld, S. K., Gao, Y., Wang, J., Horgusluoglu, E., Bolanis, E., Clapp, D. W. & Conway, S. J., Jun 2013, In : Birth Defects Research Part A - Clinical and Molecular Teratology. 97, 6, p. 373-385 13 p.

Research output: Contribution to journalArticle

18 Scopus citations
2012

Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages

Hoeffel, G., Wang, Y., Greter, M., See, P., Teo, P., Malleret, B., Leboeuf, M., Low, D., Oller, G., Almeida, F., Choy, S. H. Y., Grisotto, M., Renia, L., Conway, S. J., Stanley, E. R., Chan, J. K. Y., Ng, L. G., Samokhvalov, I. M., Merad, M. & Ginhoux, F., Jun 4 2012, In : Journal of Experimental Medicine. 209, 6, p. 1167-1181 15 p.

Research output: Contribution to journalArticle

420 Scopus citations

A protective role for periostin and TGF-β in IgE-mediated allergy and airway hyperresponsiveness

Gordon, E. D., Sidhu, S. S., Wang, Z. E., Woodruff, P. G., Yuan, S., Solon, M. C., Conway, S. J., Huang, X., Locksley, R. M. & Fahy, J. V., Jan 2012, In : Clinical and Experimental Allergy. 42, 1, p. 144-155 12 p.

Research output: Contribution to journalArticle

66 Scopus citations

Autonomous murine T-cell progenitor production in the extra-embryonic yolk sac before HSC emergence

Yoshimoto, M., Porayette, P., Glosson, N. L., Conway, S. J., Carlesso, N., Cardoso, A. A., Kaplan, M. H. & Yoder, M. C., Jun 14 2012, In : Blood. 119, 24, p. 5706-5714 9 p.

Research output: Contribution to journalArticle

80 Scopus citations

In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes

Qian, L., Huang, Y., Spencer, C. I., Foley, A., Vedantham, V., Liu, L., Conway, S. J., Fu, J. D. & Srivastava, D., 2012, In : Nature. 485, 7400, p. 593-598 6 p.

Research output: Contribution to journalArticle

829 Scopus citations

Periostin, a matricellular protein, accelerates cutaneous wound repair by activating dermal fibroblasts

Ontsuka, K., Kotobuki, Y., Shiraishi, H., Serada, S., Ohta, S., Tanemura, A., Yang, L., Fujimoto, M., Arima, K., Suzuki, S., Murota, H., Toda, S., Kudo, A., Conway, S. J., Narisawa, Y., Katayama, I., Izuhara, K. & Naka, T., May 1 2012, In : Experimental Dermatology. 21, 5, p. 331-336 6 p.

Research output: Contribution to journalArticle

78 Scopus citations

Periostin, a matricellular protein, plays a role in the induction of chemokines in pulmonary fibrosis

Uchida, M., Shiraishi, H., Ohta, S., Arima, K., Taniguchi, K., Suzuki, S., Okamoto, M., Ahlfeld, S. K., Ohshima, K., Kato, S., Toda, S., Sagara, H., Aizawa, H., Hoshino, T., Conway, S. J., Hayashi, S. & Izuhara, K., May 1 2012, In : American journal of respiratory cell and molecular biology. 46, 5, p. 677-686 10 p.

Research output: Contribution to journalArticle

100 Scopus citations

Periostin contributes to the pathogenesis of atopic dermatitis by inducing TSLP production from keratinocytes

Shiraishi, H., Masuoka, M., Ohta, S., Suzuki, S., Arima, K., Taniguchi, K., Aoki, S., Toda, S., Yoshimoto, T., Inagaki, N., Conway, S. J., Narisawa, Y. & Izuhara, K., Jan 1 2012, In : Allergology International. 61, 4, p. 563-572 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

Periostin modulates myofibroblast differentiation during full-thickness cutaneous wound repair

Elliott, C. G., Wang, J., Guo, X., Xu, S. W., Eastwood, M., Guan, J., Leask, A., Conway, S. J. & Hamilton, D. W., Jan 1 2012, In : Journal of cell science. 125, 1, p. 121-132 12 p.

Research output: Contribution to journalArticle

86 Scopus citations

Periostin promotes chronic allergic inflammation in response to Th2 cytokines

Masuoka, M., Shiraishi, H., Ohta, S., Suzuki, S., Arima, K., Aoki, S., Toda, S., Inagaki, N., Kurihara, Y., Hayashida, S., Takeuchi, S., Koike, K., Ono, J., Noshiro, H., Furue, M., Conway, S. J., Narisawa, Y. & Izuhara, K., Jul 2 2012, In : Journal of Clinical Investigation. 122, 7, p. 2590-2600 11 p.

Research output: Contribution to journalArticle

236 Scopus citations
79 Scopus citations

The dynamic role of cardiac fibroblasts in development and disease

Lajiness, J. D. & Conway, S. J., Dec 1 2012, In : Journal of cardiovascular translational research. 5, 6, p. 739-748 10 p.

Research output: Contribution to journalArticle

29 Scopus citations
2011

Characterization of Pax3-expressing cells from adult blood vessels

Goupille, O., Pallafacchina, G., Relaix, F., Conway, S. J., Cumano, A., Robert, B., Montarras, D. & Buckingham, M., Dec 2011, In : Journal of cell science. 124, 23, p. 3980-3988 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Embryonic day 9 yolk sac and intra-embryonic hemogenic endothelium independently generate a B-1 and marginal zone progenitor lacking B-2 potential

Yoshimoto, M., Montecino-Rodriguez, E., Ferkowicz, M. J., Porayette, P., Shelley, W. C., Conway, S. J., Dorshkind, K. & Yoder, M. C., Jan 25 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 4, p. 1468-1473 6 p.

Research output: Contribution to journalArticle

149 Scopus citations

Hand2 loss-of-function in hand1-expressing cells reveals distinct roles in epicardial and coronary vessel development

Barnes, R. M., Firulli, B. A., Vandusen, N. J., Morikawa, Y., Conway, S. J., Cserjesi, P., Vincentz, J. W. & Firulli, A. B., Apr 15 2011, In : Circulation research. 108, 8, p. 940-949 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

In vitro requirement for periostin in B lymphopoiesis

Siewe, B. T., Kalis, S. L., Le, P. T., Witte, P. L., Choi, S., Conway, S. J., Druschitz, L. & Knight, K. L., Apr 7 2011, In : Blood. 117, 14, p. 3770-3779 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Notochordal and foregut abnormalities correlate with elevated neural crest apoptosis in Patch embryos

Snider, P., Simmons, O., Rogers, R., Young, R., Gosnell, M. & Conway, S. J., Jun 1 2011, In : Birth Defects Research Part A - Clinical and Molecular Teratology. 91, 6, p. 551-564 14 p.

Research output: Contribution to journalArticle

4 Scopus citations

Pax3 is essential for normal cardiac neural crest morphogenesis but is not required during migration nor outflow tract septation

Olaopa, M., Zhou, H. M., Snider, P., Wang, J., Schwartz, R. J., Moon, A. M. & Conway, S. J., Aug 15 2011, In : Developmental Biology. 356, 2, p. 308-322 15 p.

Research output: Contribution to journalArticle

38 Scopus citations

Periostin regulates goblet cell metaplasia in a model of allergic airway inflammation

Sehra, S., Yao, W., Nguyen, E. T., Ahyi, A. N. N., Tuana, F. M. B., Ahlfeld, S. K., Snider, P., Tepper, R. S., Petrache, I., Conway, S. J. & Kaplan, M. H., Apr 15 2011, In : Journal of Immunology. 186, 8, p. 4959-4966 8 p.

Research output: Contribution to journalArticle

49 Scopus citations

Probing human cardiovascular congenital disease using transgenic mouse models

Snider, P. & Conway, S., 2011, In : Progress in Molecular Biology and Translational Science. 100, p. 83-110 28 p.

Research output: Contribution to journalArticle

6 Scopus citations

SWI/SNF complexes containing brahma Brahma-related gene 1 play distinct roles in smooth muscle development

Zhang, M., Chen, M., Kim, J. R., Zhou, J., Jones, R. E., Tune, J. D., Kassab, G. S., Metzger, D., Ahlfeld, S., Conway, S. J. & Herring, B. P., Jul 2011, In : Molecular and cellular biology. 31, 13, p. 2618-2631 14 p.

Research output: Contribution to journalArticle

35 Scopus citations

The haploinsufficient hematopoietic microenvironment is critical to the pathological fracture repair in murine models of neurofibromatosis type 1

Wu, X., Chen, S., He, Y., Rhodes, S. D., Mohammad, K. S., Li, X., Yang, X., Jiang, L., Nalepa, G., Snider, P., Robling, A. G., Clapp, D. W., Conway, S. J., Guise, T. A. & Yang, F. C., Sep 29 2011, In : PLoS ONE. 6, 9, e24917.

Research output: Contribution to journalArticle

22 Scopus citations

Transforming growth factor Beta2 is required for valve remodeling during heart development

Azhar, M., Brown, K., Gard, C., Chen, H., Rajan, S., Elliott, D. A., Stevens, M. V., Camenisch, T. D., Conway, S. J. & Doetschman, T., Sep 1 2011, In : Developmental Dynamics. 240, 9, p. 2127-2141 15 p.

Research output: Contribution to journalArticle

43 Scopus citations
2010

A bHLH code for cardiac morphogenesis

Conway, S. J., Firulli, B. & Firulli, A. B., 2010, In : Pediatric Cardiology. 31, 3, p. 318-324 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Analysis of the Hand1 cell lineage reveals novel contributions to cardiovascular, neural crest, extra-embryonic, and lateral mesoderm derivatives

Barnes, R. M., Firulli, B. A., Conway, S. J., Vincentz, J. W. & Firulli, A. B., Nov 2010, In : Developmental Dynamics. 239, 11, p. 3086-3097 12 p.

Research output: Contribution to journalArticle

35 Scopus citations

Cardiac fibroblasts are essential for the adaptive response of the murine heart to pressure overload

Takeda, N., Manabe, I., Uchino, Y., Eguchi, K., Matsumoto, S., Nishimura, S., Shindo, T., Sano, M., Otsu, K., Snider, P., Conway, S. J. & Nagai, R., Jan 4 2010, In : Journal of Clinical Investigation. 120, 1, p. 254-265 12 p.

Research output: Contribution to journalArticle

244 Scopus citations

Fate mapping analysis reveals that adult microglia derive from primitive macrophages

Ginhoux, F., Greter, M., Leboeuf, M., Nandi, S., See, P., Gokhan, S., Mehler, M. F., Conway, S. J., Ng, L. G., Stanley, E. R., Samokhvalov, I. M. & Merad, M., Nov 5 2010, In : Science. 330, 6005, p. 841-845 5 p.

Research output: Contribution to journalArticle

2184 Scopus citations

Gene replacement strategies to test the functional redundancy of Basic helix-loop-helix transcription factor

Firulli, A. B., Firulli, B. A., Wang, J., Rogers, R. H. & Conway, S. J., 2010, In : Pediatric Cardiology. 31, 3, p. 438-448 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans

Lasater, E. A., Li, F., Bessler, W. K., Estes, M. L., Vemula, S., Hingtgen, C. M., Dinauer, M. C., Kapur, R., Conway, S. J. & Ingram, D. A., Mar 1 2010, In : Journal of Clinical Investigation. 120, 3, p. 859-870 12 p.

Research output: Contribution to journalArticle

51 Scopus citations

Periostin mediates vascular smooth muscle cell migration through the integrins ανβ3 and ανβ5 and focal adhesion kinase (FAK) pathway

Li, G., Jin, R., Norris, R. A., Zhang, L., Yu, S., Wu, F., Markwald, R. R., Nanda, A., Conway, S. J., Smyth, S. S. & Granger, D. N., Feb 1 2010, In : Atherosclerosis. 208, 2, p. 358-365 8 p.

Research output: Contribution to journalArticle

97 Scopus citations

Spatiotemporal expression of periostin during skin development and incisional wound healing: Lessons for human fibrotic scar formation

Zhou, H. M., Wang, J., Elliott, C., Wen, W., Hamilton, D. W. & Conway, S. J., Jun 1 2010, In : Journal of Cell Communication and Signaling. 4, 2, p. 99-107 9 p.

Research output: Contribution to journalArticle

67 Scopus citations

Trigenic neural crest-restricted Smad7 over-expression results in congenital craniofacial and cardiovascular defects

Tang, S., Snider, P., Firulli, A. B. & Conway, S. J., Aug 1 2010, In : Developmental Biology. 344, 1, p. 233-247 15 p.

Research output: Contribution to journalArticle

27 Scopus citations
2009

Adult satellite cells and embryonic muscle progenitors have distinct genetic requirements

Lepper, C., Conway, S. J. & Fan, C. M., Jul 30 2009, In : Nature. 460, 7255, p. 627-631 5 p.

Research output: Contribution to journalArticle

357 Scopus citations

Chronic administration of KB-R7943 induces up-regulation of cardiac NCX1

Xu, L., Kappler, C. S., Mani, S. K., Shepherd, N. R., Renaud, L., Snider, P., Conway, S. J. & Menick, D. R., Oct 2 2009, In : Journal of Biological Chemistry. 284, 40, p. 27265-27272 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Generation of Smad7-Cre recombinase mice: A useful tool for the study of epithelial-mesenchymal transformation within the embryonic heart

Snider, P., Tang, S., Lin, G., Wang, J. & Conway, S. J., 2009, In : Genesis. 47, 7, p. 469-475 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease

Tkatchenko, T. V., Moreno-Rodriguez, R. A., Conway, S. J., Molkentin, J. D., Markwald, R. R. & Tkatchenko, A. V., Nov 2009, In : Physiological Genomics. 39, 3, p. 160-168 9 p.

Research output: Contribution to journalArticle

61 Scopus citations

Muscle stem cell behavior is modified by microRNA-27 regulation of Pax3 expression

Crist, C. G., Montarras, D., Pallafacchina, G., Rocancourt, D., Cumano, A., Conway, S. J. & Buckinghama, M., Aug 11 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 32, p. 13383-13387 5 p.

Research output: Contribution to journalArticle

226 Scopus citations

The matricellular protein periostin is required for sost inhibition and the anabolic response to mechanical loading and physical activity

Bonnet, N., Standley, K. N., Bianchi, E. N., Stadelmann, V., Foti, M., Conway, S. J. & Ferrari, S. L., Dec 18 2009, In : Journal of Biological Chemistry. 284, 51, p. 35939-35950 12 p.

Research output: Contribution to journalArticle

126 Scopus citations
2008

All primitive and definitive hematopoietic progenitor cells emerging before E10 in the mouse embryo are products of the yolk sac

Lux, C. T., Yoshimoto, M., McGrath, K., Conway, S. J., Palis, J. & Yoder, M. C., Apr 1 2008, In : Blood. 111, 7, p. 3435-3438 4 p.

Research output: Contribution to journalArticle

190 Scopus citations

An absence of Twist1 results in aberrant cardiac neural crest morphogenesis

Vincentz, J. W., Barnes, R. M., Rodgers, R., Firulli, B. A., Conway, S. J. & Firulli, A. B., Aug 1 2008, In : Developmental Biology. 320, 1, p. 131-139 9 p.

Research output: Contribution to journalArticle

50 Scopus citations

Cooperative interaction of Nkx2.5 and Mef2c transcription factors during heart development

Vincentz, J. W., Barnes, R. M., Firulli, B. A., Conway, S. J. & Firulli, A. B., Dec 2008, In : Developmental Dynamics. 237, 12, p. 3809-3819 11 p.

Research output: Contribution to journalArticle

52 Scopus citations

Generation and characterization of Csrp1 enhancer-driven tissue-restricted Cre-recombinase mice

Snider, P., Fix, J. L., Rogers, R., Peabody-Dowling, G., Ingram, D., Lilly, B. & Conway, S. J., Mar 2008, In : Genesis. 46, 3, p. 167-176 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Lineage-specific responses to reduced embryonic Pax3 expression levels

Zhou, H. M., Wang, J., Rogers, R. & Conway, S. J., Mar 15 2008, In : Developmental Biology. 315, 2, p. 369-382 14 p.

Research output: Contribution to journalArticle

23 Scopus citations

Nf1+/- mice have increased neointima formation via hyperactivation of a Gleevec sensitive molecular pathway

Lasater, E. A., Bessler, W. K., Mead, L. E., Horn, W. E., Clapp, D. W., Conway, S. J., Ingram, D. A. & Li, F., Aug 2008, In : Human molecular genetics. 17, 15, p. 2336-2344 9 p.

Research output: Contribution to journalArticle

52 Scopus citations