Simon Conway

  • 17303 Citations
  • 64 h-Index
1994 …2020

Research output per year

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2008

Periostin is essential for the integrity and function of the periodontal ligament during occlusal loading in mice

Rios, H. F., Ma, D., Xie, Y., Giannobile, W. V., Bonewald, L. F., Conway, S. J. & Feng, J. Q., Aug 1 2008, In : Journal of periodontology. 79, 8, p. 1480-1490 11 p.

Research output: Contribution to journalArticle

145 Scopus citations

Periostin is required for maturation and extracellular matrix stabilization of noncardiomyocyte lineages of the heart

Snider, P., Hinton, R. B., Moreno-Rodriguez, R. A., Wang, J., Rogers, R., Lindsley, A., Li, F., Ingram, D. A., Menick, D., Field, L., Firulli, A. B., Molkentin, J. D., Markwald, R. & Conway, S. J., Apr 2008, In : Circulation research. 102, 7, p. 752-760 9 p.

Research output: Contribution to journalArticle

222 Scopus citations

Serum response factor orchestrates nascent sarcomerogenesis and silences the biomineralization gene program in the heart

Niu, Z., Iyer, D., Conway, S. J., Martin, J. F., Ivey, K., Srivastava, D., Nordheim, A. & Schwartz, R. J., Nov 18 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 46, p. 17824-17829 6 p.

Research output: Contribution to journalArticle

78 Scopus citations

The Emergence of Hematopoietic Stem Cells Is Initiated in the Placental Vasculature in the Absence of Circulation

Rhodes, K. E., Gekas, C., Wang, Y., Lux, C. T., Francis, C. S., Chan, D. N., Conway, S., Orkin, S. H., Yoder, M. C. & Mikkola, H. K. A., Mar 6 2008, In : Cell Stem Cell. 2, 3, p. 252-263 12 p.

Research output: Contribution to journalArticle

211 Scopus citations

The Loss of Nf1 Transiently Promotes Self-Renewal but Not Tumorigenesis by Neural Crest Stem Cells

Joseph, N. M., Mosher, J. T., Buchstaller, J., Snider, P., McKeever, P. E., Lim, M., Conway, S. J., Parada, L. F., Zhu, Y. & Morrison, S. J., Feb 5 2008, In : Cancer Cell. 13, 2, p. 129-140 12 p.

Research output: Contribution to journalArticle

105 Scopus citations
2007

Genetic manipulation of periostin expression reveals a role in cardiac hypertrophy and ventricular remodeling

Oka, T., Xu, J., Kaiser, R. A., Melendez, J., Hambleton, M., Sargent, M. A., Lorts, A., Brunskill, E. W., Dorn, G. W., Conway, S. J., Aronow, B. J., Robbins, J. & Molkentin, J. D., Aug 1 2007, In : Circulation research. 101, 3, p. 313-321 9 p.

Research output: Contribution to journalArticle

308 Scopus citations

Identification and characterization of a novel Schwann and outflow tract endocardial cushion lineage-restricted periostin enhancer

Lindsley, A., Snider, P., Zhou, H., Rogers, R., Wang, J., Olaopa, M., Kruzynska-Frejtag, A., Koushik, S. V., Lilly, B., Burch, J. B. E., Firulli, A. B. & Conway, S. J., Jul 15 2007, In : Developmental Biology. 307, 2, p. 340-355 16 p.

Research output: Contribution to journalArticle

70 Scopus citations

Lack of endothelial cell survivin causes embryonic defects in angiogenesis, cardiogenesis, and neural tube closure

Zwerts, F., Lupu, F., De Vriese, A., Pollefeyt, S., Moons, L., Altura, R. A., Jiang, Y., Maxwell, P. H., Hill, P., Oh, H., Rieker, C., Collen, D., Conway, S. J. & Conway, E. M., Jun 1 2007, In : Blood. 109, 11, p. 4742-4752 11 p.

Research output: Contribution to journalArticle

57 Scopus citations

Mutations within helix I of twist1 result in distinct limb defects and variation of DNA binding affinities

Firulli, B. A., Redick, B. A., Conway, S. J. & Firulli, A. B., Sep 14 2007, In : Journal of Biological Chemistry. 282, 37, p. 27536-27546 11 p.

Research output: Contribution to journalArticle

60 Scopus citations

Periostin regulates collagen fibrillogenesis and the biomechanical properties of connective tissues

Morris, R. A., Damon, B., Mironov, V., Kasyanov, V., Ramamurthi, A., Moreno-Rodriguez, R., Trusk, T., Potts, J. D., Goodwin, R. L., Davis, J., Hoffman, S., Wen, X., Sugi, Y., Kern, C. B., Mjaatvedt, C. H., Turner, D. K., Oka, T., Conway, S. J., Molkentin, J. D., Forgacs, G. & 1 others, Markwald, R. R., Jun 1 2007, In : Journal of Cellular Biochemistry. 101, 3, p. 695-711 17 p.

Research output: Contribution to journalArticle

384 Scopus citations
2006

Functional Characteristics of NaS2, a Placenta-specific Na+-coupled Transporter for Sulfate and Oxyanions of the Micronutrients Selenium and Chromium

Miyauchi, S., Srinivas, S. R., Fei, Y. J., Gopal, E., Umapathy, N. S., Wang, H., Conway, S. J., Ganapathy, V. & Prasad, P. D., Jun 1 2006, In : Placenta. 27, 6-7, p. 550-559 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Intragenic deletion of Tgif causes defects in brain development

Kuang, C., Xiao, Y., Yang, L., Chen, Q., Wang, Z., Conway, S. J. & Chen, Y., Dec 15 2006, In : Human molecular genetics. 15, 24, p. 3508-3519 12 p.

Research output: Contribution to journalArticle

31 Scopus citations

Phosphatidylinositol-3-kinase signaling mediates vascular smooth muscle cell expression of periostin in vivo and in vitro

Li, G., Oparil, S., Sanders, J. M., Zhang, L., Dai, M., Chen, L. B., Conway, S. J., McNamara, C. A. & Sarembock, I. J., Oct 1 2006, In : Atherosclerosis. 188, 2, p. 292-300 9 p.

Research output: Contribution to journalArticle

76 Scopus citations

Regulation of Ncx1 expression: Identification of regulatory elements mediating cardiac-specific expression and up-regulation

Xu, L., Renaud, L., Müller, J. G., Baicu, C. F., Bonnema, D. D., Zhou, H., Kappler, C. S., Kubalak, S. W., Zile, M. R., Conway, S. J. & Menick, D. R., Nov 10 2006, In : Journal of Biological Chemistry. 281, 45, p. 34430-34440 11 p.

Research output: Contribution to journalArticle

21 Scopus citations
2005

Alk3/Bmpr1a receptor is required for development of the atrioventricular canal into valves and annulus fibrosus

Gaussin, V., Morley, G. E., Cox, L., Zwijsen, A., Vance, K. M., Emile, L., Tian, Y., Liu, J., Hong, C., Myers, D., Conway, S. J., Depre, C., Mishina, Y., Behringer, R. R., Hanks, M. C., Schneider, M. D., Huylebroeck, D., Fishman, G. I., Burch, J. B. E. & Vatner, S. F., Aug 5 2005, In : Circulation research. 97, 3, p. 219-226 8 p.

Research output: Contribution to journalArticle

107 Scopus citations

Altered Twist1 and Hand2 dimerization is associated with Saethre-Chotzen syndrome and limb abnormalities

Firulli, B. A., Krawchuk, D., Centonze, V. E., Vargesson, N., Virshup, D. M., Conway, S. J., Cserjesi, P., Laufer, E. & Firulli, A. B., Apr 1 2005, In : Nature genetics. 37, 4, p. 373-381 9 p.

Research output: Contribution to journalArticle

129 Scopus citations

Comparison of the four mouse fasciclin-containing genes expression patterns during valvuloseptal morphogenesis

Lindsley, A., Li, W., Wang, J., Maeda, N., Rogers, R. & Conway, S. J., Jun 1 2005, In : Gene Expression Patterns. 5, 5, p. 593-600 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

periostin null mice exhibit dwarfism, incisor enamel defects, and an early-onset periodontal disease-like phenotype

Rios, H., Koushik, S. V., Wang, H., Wang, J., Zhou, H. M., Lindsley, A., Rogers, R., Chen, Z., Maeda, M., Kruzynska-Frejtag, A., Feng, J. Q. & Conway, S. J., Dec 2005, In : Molecular and cellular biology. 25, 24, p. 11131-11144 14 p.

Research output: Contribution to journalArticle

282 Scopus citations
2004

BMP10 is essential for maintaining cardiac growth during murine cardiogenesis

Chen, H., Shi, S., Acosta, L., Li, W., Lu, J., Bao, S., Chen, Z., Yang, Z., Schneider, M. D., Chien, K. R., Conway, S. J., Yoder, M. C., Haneline, L. S., Franco, D. & Shou, W., May 1 2004, In : Development. 131, 9, p. 2219-2231 13 p.

Research output: Contribution to journalArticle

314 Scopus citations

Periostin Is Expressed Within the Developing Teeth at the Sites of Epithelial-Mesenchymal Interaction

Kruzynska-Frejtag, A., Wang, J., Maeda, M., Rogers, R., Krug, E., Hoffman, S., Markwald, R. R. & Conway, S. J., Apr 2004, In : Developmental Dynamics. 229, 4, p. 857-868 12 p.

Research output: Contribution to journalArticle

116 Scopus citations

SDF-1 (CXCL12) Is Upregulated in the Ischemic Penumbra Following Stroke: Association with Bone Marrow Cell Homing to Injury

Hill, W. D., Hess, D. C., Martin-Studdard, A., Carothers, J. J., Zheng, J., Hale, D., Maeda, M., Fagan, S. C., Carroll, J. E. & Conway, S. J., Jan 2004, In : Journal of Neuropathology and Experimental Neurology. 63, 1, p. 84-96 13 p.

Research output: Contribution to journalArticle

Open Access
318 Scopus citations

The LTR enhancer of ERV-9 human endogenous retrovirus is active in oocytes and progenitor cells in transgenic zebrafish and humans

Pi, W., Yang, Z., Wang, J., Ruan, L., Yu, X., Ling, J., Krantz, S., Isales, C., Conway, S. J., Lin, S. & Tuan, D., Jan 20 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 3, p. 805-810 6 p.

Research output: Contribution to journalArticle

31 Scopus citations
2003

Tbx1 is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer

Yamagishi, H., Maeda, J., Hu, T., McAnally, J., Conway, S. J., Kume, T., Meyers, E. N., Yamagishi, C. & Srivastava, D., Jan 15 2003, In : Genes and Development. 17, 2, p. 269-281 13 p.

Research output: Contribution to journalArticle

201 Scopus citations

VEGF: A modifier of the de122q11 (DiGeorge) syndrome?

Stalmans, I., Lambrechts, D., De Smet, F., Jansen, S., Wang, J., Maity, S., Kneer, P., Der Ohe, M. V., Swillen, A., Maes, C., Gewillig, M., Molin, D. G. M., Hellings, P., Boetel, T., Haardt, M., Compernolle, V., Dewerchin, M., Plaisance, S., Vlietinck, R., Emanuel, B. & 12 others, Gittenberger-de Groot, A. C., Scambler, P., Morrow, B., Driscol, D. A., Moons, L., Esguerra, C. V., Carmeliet, G., Behn-Krappa, A., Devriendt, K., Collen, D., Conway, S. J. & Carmeliet, P., Feb 1 2003, In : Nature Medicine. 9, 2, p. 173-182 10 p.

Research output: Contribution to journalArticle

234 Scopus citations
2002

Cardiac-specific expression and hypertrophic upregulation of the feline Na+-Ca2+ exchanger gene H1-promoter in a transgenic mouse model

Müller, J. G., Isomatsu, Y., Koushik, S. V., O'Quinn, M., Xu, L., Kappler, C. S., Hapke, E., Zile, M. R., Conway, S. J. & Menick, D. R., Feb 8 2002, In : Circulation research. 90, 2, p. 158-164 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Generation of a conditional loxP allele of the Pax3 transcription factor that enables selective deletion of the homeodomain

Koushik, S. V., Chen, H., Wang, J. & Conway, S. J., 2002, In : Genesis. 32, 2, p. 114-117 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Pathways regulating Na+/Ca2+ exchanger expression in the heart

Menick, D. R., Xu, L., Kappler, C., Jiang, W., Withers, P. R., Shepherd, N., Conway, S. J. & Müller, J. G., 2002, In : Annals of the New York Academy of Sciences. 976, p. 237-247 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Pax3-FKHR knock-in mice show developmental aberrations but do not develop tumors

Lagutina, I., Conway, S. J., Sublett, J. & Grosveld, G. C., Oct 1 2002, In : Molecular and cellular biology. 22, 20, p. 7204-7216 13 p.

Research output: Contribution to journalArticle

66 Scopus citations

Role of sodium-calcium exchanger (Ncx1) in embryonic heart development: A Transgenic Rescue?

Conway, S. J., Kruzynska-Frejtag, A., Wang, J., Rogers, R., Kneer, P. L., Chen, H., Creazzo, T., Menick, D. R. & Koushik, S. V., 2002, In : Annals of the New York Academy of Sciences. 976, p. 268-281 14 p.

Research output: Contribution to journalArticle

14 Scopus citations
2001

Cardiovascular defects associated with abnormalities in midline development in the Loop-tail mouse mutant

Henderson, D. J., Conway, S. J., Greene, N. D. E., Gerrelli, D., Murdoch, J. N., Anderson, R. H. & Copp, A. J., Jul 6 2001, In : Circulation research. 89, 1, p. 6-12 7 p.

Research output: Contribution to journalArticle

Open Access
59 Scopus citations

Expression pattern of the type 1 sigma receptor in the brain and identity of critical anionic amino acid residues in the ligand-binding domain of the receptor

Seth, P., Ganapathy, M. E., Conway, S. J., Bridges, C. D., Smith, S. B., Casellas, P. & Ganapathy, V., Jul 25 2001, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1540, 1, p. 59-67 9 p.

Research output: Contribution to journalArticle

70 Scopus citations

Periostin (an osteoblast-specific factor) is expressed within the embryonic mouse heart during valve formation

Kruzynska-Frejtag, A., Machnicki, M., Rogers, R., Markwald, R. R. & Conway, S. J., May 1 2001, In : Mechanisms of Development. 103, 1-2, p. 183-188 6 p.

Research output: Contribution to journalArticle

169 Scopus citations

Targeted inactivation of the sodium-calcium exchanger (Ncx1) results in the lack of a heartbeat and abnormal myofibrillar organization.

Koushik, S. V., Wang, J., Rogers, R., Moskophidis, D., Lambert, N. A., Creazzo, T. L. & Conway, S. J., May 2001, In : The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 15, 7, p. 1209-1211 3 p.

Research output: Contribution to journalArticle

200 Scopus citations
2000

Decreased neural crest stem cell expansion is responsible for the conotruncal heart defects within the Splotch (Sp(2H))/Pax3 mouse mutant

Conway, S. J., Bundy, J., Chen, J., Dickman, E., Rogers, R. & Will, B. M., Aug 1 2000, In : Cardiovascular research. 47, 2, p. 314-328 15 p.

Research output: Contribution to journalArticle

87 Scopus citations

Differential influence of the 4F2 heavy chain and the protein related to b0,+ amino acid transport on substrate affinity of the heteromeric b0,+ amino acid transporter

Rajan, D. P., Huang, W., Kekuda, R., George, R. L., Wang, J., Conway, S. J., Devoe, L. D., Leibach, F. H., Prasad, P. D. & Ganapathy, V., May 12 2000, In : Journal of Biological Chemistry. 275, 19, p. 14331-14335 5 p.

Research output: Contribution to journalArticle

44 Scopus citations

Jumonji, a nuclear protein that is necessary for normal heart development

Lee, Y., Song, A. J., Baker, R., Micales, B., Conway, S. J. & Lyons, G. E., May 12 2000, In : Circulation research. 86, 9, p. 932-938 7 p.

Research output: Contribution to journalArticle

Open Access
109 Scopus citations

Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta

Wu, X., George, R. L., Huang, W., Wang, H., Conway, S. J., Leibach, F. H. & Ganapathy, V., Jun 1 2000, In : Biochimica et Biophysica Acta - Biomembranes. 1466, 1-2, p. 315-327 13 p.

Research output: Contribution to journalArticle

168 Scopus citations

Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney

Wu, X., Wei, H., Ganapathy, M. E., Wang, H., Kekuda, R., Conway, S. J., Leibach, F. H. & Ganapathy, V., Jan 1 2000, In : American Journal of Physiology - Renal Physiology. 279, 3 48-3, p. F449-F458

Research output: Contribution to journalArticle

139 Scopus citations

Transport of N-acetylaspartate by the Na+-dependent high-affinity dicarboxylate transporter NaDC3 and its relevance to the expression of the transporter in the brain

Huang, W., Wang, H., Kekuda, R., Fei, Y. J., Friedrich, A., Wang, J., Conway, S. J., Cameron, R. S., Leibach, F. H. & Ganapathy, V., Oct 16 2000, In : Journal of Pharmacology and Experimental Therapeutics. 295, 1, p. 392-403 12 p.

Research output: Contribution to journalArticle

62 Scopus citations
1999
33 Scopus citations

Distinct spatial and temporal distributions of aggrecan and versican in the embryonic chick heart

Zanin, M. K. B., Bundy, J., Ernst, H., Wessels, A., Conway, S. J. & Hoffman, S., Dec 1 1999, In : Anatomical Record. 256, 4, p. 366-380 15 p.

Research output: Contribution to journalArticle

39 Scopus citations

Expression of folate receptor α in the mammalian retinol pigmented epithelium and retina

Smith, S. B., Kekuda, R., Gu, X., Chancy, C., Conway, S. J. & Ganapathy, V., Apr 13 1999, In : Investigative Ophthalmology and Visual Science. 40, 5, p. 840-848 9 p.

Research output: Contribution to journalArticle

37 Scopus citations

Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter

Wu, X., Huang, W., Prasad, P. D., Seth, P., Rajan, D. P., Leibach, F. H., Chen, J., Conway, S. J. & Ganapathy, V., Sep 1999, In : Journal of Pharmacology and Experimental Therapeutics. 290, 3, p. 1482-1492 11 p.

Research output: Contribution to journalArticle

292 Scopus citations

HLA-G transgenic mice

Mellor, A., Zhou, M., Conway, S. J. & Munn, D., Jul 1 1999, In : Journal of Reproductive Immunology. 43, 2, p. 253-261 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Novel expression of the goosecoid transcription factor in the embryonic mouse heart

Conway, S. J., Mar 1 1999, In : Mechanisms of Development. 81, 1-2, p. 187-191 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Rib truncations and fusions in the Sp(2H) mouse reveal a role for Pax3 in specification of the ventro-lateral and posterior parts of the somite

Henderson, D. J., Conway, S. J. & Copp, A. J., May 1 1999, In : Developmental Biology. 209, 1, p. 143-158 16 p.

Research output: Contribution to journalArticle

61 Scopus citations

Roles for the winged helix transcription factors MF1 and MFH1 in cardiovascular development revealed by nonallelic noncomplementation of null alleles

Winnier, G. E., Kume, T., Deng, K., Rogers, R., Bundy, J., Raines, C., Walter, M. A., Hogan, B. L. M. & Conway, S. J., Sep 15 1999, In : Developmental Biology. 213, 2, p. 418-431 14 p.

Research output: Contribution to journalArticle

138 Scopus citations

Sodium-calcium exchanger is initially expressed in a heart-restricted pattern within the early mouse embryo

Koushik, S. V., Bundy, J. & Conway, S. J., Oct 1 1999, In : Mechanisms of Development. 88, 1, p. 119-122 4 p.

Research output: Contribution to journalArticle

29 Scopus citations

The mammalian Tolloid-like 1 gene, Tll1, is necessary for normal septation and positioning of the heart

Clark, T. G., Conway, S. J., Scott, I. C., Labosky, P. A., Winnier, G., Bundy, J., Hogan, B. L. M. & Greenspan, D. S., Jun 1999, In : Development. 126, 12, p. 2631-2642 12 p.

Research output: Contribution to journalArticle

98 Scopus citations
1998

Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brain

Wu, X., Kekuda, R., Huang, W., Fei, Y. J., Leibach, F. H., Chen, J., Conway, S. J. & Ganapathy, V., Dec 4 1998, In : Journal of Biological Chemistry. 273, 49, p. 32776-32786 11 p.

Research output: Contribution to journalArticle

303 Scopus citations