Simon Rhodes

  • 3877 Citations
  • 32 h-Index
1989 …2015

Research output per year

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Publications

  • 3877 Citations
  • 32 h-Index
  • 71 Article
  • 9 Review article
2015

Novel lethal form of congenital hypopituitarism associated with the first recessive LHX4 mutation

Gregory, L. C., Humayun, K. N., Turton, J. P. G., McCabe, M. J., Rhodes, S. J. & Dattani, M. T., Jun 1 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 6, p. 2158-2164 7 p.

Research output: Contribution to journalArticle

17 Scopus citations
2014

Porcine sst1 can physically interact with other somatostatin receptors, and its expression is regulated by metabolic/inflammatory sensors

Gahete, M. D., Durán-Prado, M., Delgado-Niebla, E., Garrido, J. J., Rhodes, S. J., García-Navarro, S., Gracia-Navarro, F., Malagón, M. M., Luque, R. M. & Castaño, J. P., Jan 1 2014, In : American Journal of Physiology - Endocrinology and Metabolism. 306, 5, p. E483-E493

Research output: Contribution to journalArticle

1 Scopus citations

Student development in an experiential learning program

Gilbert, B. L., Banks, J., Houser, J. H. W., Rhodes, S. J. & Douglas Lees, N., Oct 1 2014, In : Journal of College Student Development. 55, 7, p. 707-713 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

The role of DNA methylation in regulation of the murine Lhx3 gene

Malik, R. E. & Rhodes, S. J., Jan 25 2014, In : Gene. 534, 2, p. 272-281 10 p.

Research output: Contribution to journalArticle

3 Scopus citations
2013

Cell-specific actions of a human LHX3 gene enhancer during pituitary and spinal cord development

Park, S., Mullen, R. D. & Rhodes, S. J., Dec 1 2013, In : Molecular Endocrinology. 27, 12, p. 2013-2027 15 p.

Research output: Contribution to journalArticle

10 Scopus citations

Developmental analysis and influence of genetic background on the Lhx3 W227ter mouse model of combined pituitary hormone deficiency disease

Prince, K. L., Colvin, S. C., Park, S., Lai, X., Witzmann, F. A. & Rhodes, S. J., Feb 1 2013, In : Endocrinology. 154, 2, p. 738-748 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

LHX3 Interacts with Inhibitor of Histone Acetyltransferase Complex Subunits LANP and TAF-1β to Modulate Pituitary Gene Regulation

Hunter, C. S., Malik, R. E., Witzmann, F. A. & Rhodes, S. J., Jul 4 2013, In : PloS one. 8, 7, e68898.

Research output: Contribution to journalArticle

7 Scopus citations
2012

A recessive mutation resulting in a disabling amino acid substitution (T194R) in the LHX3 homeodomain causes combined pituitary hormone deficiency

Pozza, S. B. D., Hiedl, S., Roeb, J., Lohse, P., Malik, R. E., Park, S., Durán-Prado, M. & Rhodes, S. J., Feb 1 2012, In : Hormone Research in Paediatrics. 77, 1, p. 41-51 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

Distal modular enhancer complex acts to control pituitary-and nervous system-specific expression of the LHX3 regulatory gene

Mullen, R. D., Park, S. & Rhodes, S. J., Feb 1 2012, In : Molecular Endocrinology. 26, 2, p. 308-319 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Phosphatase of regenerating liver 2 (PRL2) is essential for placental development by down-regulating PTEN (phosphatase and tensin homologue deleted on chromosome 10) and activating Akt protein

Dong, Y., Zhang, L., Zhang, S., Bai, Y., Chen, H., Sun, X., Yong, W., Li, W., Colvin, S. C., Rhodes, S. J., Shou, W. & Zhang, Z. Y., Sep 14 2012, In : Journal of Biological Chemistry. 287, 38, p. 32172-32179 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

The transcription factor encyclopedia.

Yusuf, D., Butland, S. L., Swanson, M. I., Bolotin, E., Ticoll, A., Cheung, W. A., Zhang, X. Y. C., Dickman, C. T. D., Fulton, D. L., Lim, J. S., Schnabl, J. M., Ramos, O. H. P., Vasseur-Cognet, M., de Leeuw, C. N., Simpson, E. M., Ryffel, G. U., Lam, E. W. F., Kist, R., Wilson, M. S. C., Marco-Ferreres, R. & 79 others, Brosens, J. J., Beccari, L. L., Bovolenta, P., Benayoun, B. A., Monteiro, L. J., Schwenen, H. D. C., Grontved, L., Wederell, E., Mandrup, S., Veitia, R. A., Chakravarthy, H., Hoodless, P. A., Mancarelli, M. M., Torbett, B. E., Banham, A. H., Reddy, S. P., Cullum, R. L., Liedtke, M., Tschan, M. P., Vaz, M., Rizzino, A., Zannini, M., Frietze, S., Farnham, P. J., Eijkelenboom, A., Brown, P. J., Laperrière, D., Leprince, D., de Cristofaro, T., Prince, K. L., Putker, M., del Peso, L., Camenisch, G., Wenger, R. H., Mikula, M., Rozendaal, M., Mader, S., Ostrowski, J., Rhodes, S. J., Van Rechem, C., Boulay, G., Olechnowicz, S. W. Z., Breslin, M. B., Lan, M. S., Nanan, K. K., Wegner, M., Hou, J., Mullen, R. D., Colvin, S. C., Noy, P. J., Webb, C. F., Witek, M. E., Ferrell, S., Daniel, J. M., Park, J., Waldman, S. A., Peet, D. J., Taggart, M., Jayaraman, P. S., Karrich, J. J., Blom, B., Vesuna, F., O'Geen, H., Sun, Y., Gronostajski, R. M., Woodcroft, M. W., Hough, M. R., Chen, E., Europe-Finner, G. N., Karolczak-Bayatti, M., Bailey, J., Hankinson, O., Raman, V., LeBrun, D. P., Biswal, S., Harvey, C. J., DeBruyne, J. P., Hogenesch, J. B. & Hevner, R. F., 2012, In : Genome biology. 13, 3, p. R24

Research output: Contribution to journalArticle

65 Scopus citations
2011

Model of pediatric pituitary hormone deficiency separates the endocrine and neural functions of the LHX3 transcription factor in vivo

Colvin, S. C., Malik, R. E., Showalter, A. D., Sloop, K. W. & Rhodes, S. J., Jan 4 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 1, p. 173-178 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

The role of homeodomain transcription factors in heritable pituitary disease

Prince, K. L., Walvoord, E. C. & Rhodes, S. J., Dec 1 2011, In : Nature Reviews Endocrinology. 7, 12, p. 727-737 11 p.

Research output: Contribution to journalReview article

31 Scopus citations
2010

Diversifying biomedical training: A synergistic intervention

Gibau, G. S., Foertsch, J., Blum, J., Brutkiewicz, R., Queener, S., Roman, A., Rhodes, S., Sturek, M., Wilkes, D. & Broxmeyer, H., 2010, In : Journal of Women and Minorities in Science and Engineering. 16, 3, p. 215-235 21 p.

Research output: Contribution to journalArticle

10 Scopus citations
2009

BMP7 and SHH regulate Pax2 in mouse retinal astrocytes by relieving TLX repression

Sehgal, R., Sheibani, N., Rhodes, S. J. & Belecky Adams, T. L., Aug 15 2009, In : Developmental Biology. 332, 2, p. 429-443 15 p.

Research output: Contribution to journalArticle

28 Scopus citations

LHX3 and LHX4 transcription factors in pituitary development and disease

Colvin, S. C., Mullen, R. D., Pfaeffle, R. W. & Rhodes, S. J., Jan 1 2009, In : Pediatric Endocrinology Reviews. 6, SUPPL. 2, p. 283-290 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Molecular analysis of novel PROP1 mutations associated with combined pituitary hormone deficiency (CPHD)

Kelberman, D., Turton, J. P. G., Woods, K. S., Mehta, A., Al-Khawari, M., Greening, J., Swift, P. G. F., Otonkoski, T., Rhodes, S. J. & Dattani, M. T., Jan 2009, In : Clinical Endocrinology. 70, 1, p. 96-103 8 p.

Research output: Contribution to journalArticle

29 Scopus citations
2008

Three novel missense mutations within the LHX4 gene are associated with variable pituitary hormone deficiencies

Pfaeffle, R. W., Hunter, C. S., Savage, J. J., Duran-Prado, M., Mullen, R. D., Neeb, Z. P., Eiholzer, U., Hesse, V., Haddad, N. G., Stobbe, H. M., Blum, W. F., Weigel, J. F. W. & Rhodes, S. J., Mar 2008, In : Journal of Clinical Endocrinology and Metabolism. 93, 3, p. 1062-1071 10 p.

Research output: Contribution to journalArticle

78 Scopus citations
2007

Comparative genomics reveals functional transcriptional control sequences in the Prop1 gene

Ward, R. D., Davis, S. W., Cho, M. C., Esposito, C., Lyons, R. H., Cheng, J. F., Rubin, E. M., Rhodes, S. J., Raetzman, L. T., Smith, T. P. L. & Camper, S. A., Jul 1 2007, In : Mammalian Genome. 18, 6-7, p. 521-537 17 p.

Research output: Contribution to journalArticle

17 Scopus citations

Four novel mutations of the LHX3 gene cause combined pituitary hormone deficiencies with or without limited neck rotation

Pfaeffle, R. W., Savage, J. J., Hunter, C. S., Palme, C., Ahlmann, M., Kumar, P., Bellone, J., Schoenau, E., Korsch, E., Brämswig, J. H., Stobbe, H. M., Blum, W. F. & Rhodes, S. J., May 2007, In : Journal of Clinical Endocrinology and Metabolism. 92, 5, p. 1909-1919 11 p.

Research output: Contribution to journalArticle

76 Scopus citations

Identification and expression of Hop, an atypical homebox gene expressed late in lens fiber cell terminal differentiation

Vasiliev, O., Rhodes, S. J. & Beebe, D. C., Jan 26 2007, In : Molecular vision. 13, p. 114-124 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Mutations in the LHX3 gene cause dysregulation of pituitary and neural target genes that reflect patient phenotypes

Savage, J. J., Hunter, C. S., Clark-Sturm, S. L., Jacob, T. M., Pfaeffle, R. W. & Rhodes, S. J., Oct 1 2007, In : Gene. 400, 1-2, p. 44-51 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Porcine somatostatin receptor 2 displays typical pharmacological sst2 features but unique dynamics of homodimerization and internalization

Durán-Prado, M., Bucharles, C., Gonzalez, B. J., Vázquez-Martínez, R., Martínez-Fuentes, A. J., García-Navarro, S., Rhodes, S. J., Vaudry, H., Malagón, M. M. & Castaño, J. P., 2007, In : Endocrinology. 148, 1, p. 411-421 11 p.

Research output: Contribution to journalArticle

25 Scopus citations

Roles of the LHX3 and LHX4 LIM-homeodomain factors in pituitary development

Mullen, R. D., Colvin, S. C., Hunter, C. S., Savage, J. J., Walvoord, E. C., Bhangoo, A. P. S., Ten, S., Weigel, J., Pfäffle, R. W. & Rhodes, S. J., Feb 1 2007, In : Molecular and Cellular Endocrinology. 265-266, SUPPL., p. 190-195 6 p.

Research output: Contribution to journalReview article

58 Scopus citations

Transgenic mice expressing LHX3 transcription factor isoforms in the pituitary: Effects on the gonadotrope axis and sex-specific reproductive disease

Savage, J. J., Mullen, R. D., Sloop, K. W., Colvin, S. C., Camper, S. A., Franklin, C. L. & Rhodes, S. J., Jul 1 2007, In : Journal of cellular physiology. 212, 1, p. 105-117 13 p.

Research output: Contribution to journalArticle

11 Scopus citations
2006

A novel LHX3 mutation presenting as combined pituitary hormonal deficiency

Bhangoo, A. P. S., Hunter, C. S., Savage, J. J., Anhalt, H., Pavlakis, S., Walvoord, E. C., Ten, S. & Rhodes, S. J., Mar 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 3, p. 747-753 7 p.

Research output: Contribution to journalArticle

66 Scopus citations

The LIM-homeodomain proteins Isl-1 and Lhx3 act with steroidogenic factor 1 to enhance gonadotrope-specific activity of the gonadotropin-releasing hormone receptor gene promoter

Granger, A., Bleux, C., Kottler, M. L., Rhodes, S. J., Counis, R. & Laverrière, J. N., 2006, In : Molecular Endocrinology. 20, 9, p. 2093-2108 16 p.

Research output: Contribution to journalArticle

42 Scopus citations

Two promoters mediate transcription from the human LHX3 gene: Involvement of nuclear factor I and specificity protein 1

Yaden, B. C., Garcia, M., Smith, T. P. L. & Rhodes, S. J., Jan 2006, In : Endocrinology. 147, 1, p. 324-337 14 p.

Research output: Contribution to journalArticle

17 Scopus citations
2005

DNA recognition properties of the LHX3b LIM homeodomain transcription factor

Yaden, B. C., Savage, J. J., Hunter, C. S. & Rhodes, S. J., Mar 1 2005, In : Molecular Biology Reports. 32, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

LIM-homeodomain genes in mammalian development and human disease

Hunter, C. S. & Rhodes, S. J., Jun 1 2005, In : Molecular Biology Reports. 32, 2, p. 67-77 11 p.

Research output: Contribution to journalReview article

86 Scopus citations

Serine/threonine/tyrosine phosphorylation of the LHX3 LIM-homeodomain transcription factor

Parker, G. E., West, B. E., Witzmann, F. A. & Rhodes, S. J., Jan 1 2005, In : Journal of Cellular Biochemistry. 94, 1, p. 67-80 14 p.

Research output: Contribution to journalArticle

9 Scopus citations

Two promoters control the mouse Nmp4/CIZ transcription factor gene

Alvarez, M., Shah, R., Rhodes, S. J. & Bidwell, J. P., Feb 28 2005, In : Gene. 347, 1, p. 43-54 12 p.

Research output: Contribution to journalArticle

10 Scopus citations
2004

Cloning and Analysis of Axolotl ISL2 and LHX2 LIM-Homeodomain Transcription Factors

Showalter, A. D., Yaden, B. C., Chernoff, E. A. G. & Rhodes, S. J., Mar 1 2004, In : Genesis. 38, 3, p. 110-121 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Conserved amino acid sequences confer nuclear localization upon the Prophet of Pit-1 pituitary transcription factor protein

Guy, J. C., Hunter, C. S., Showalter, A. D., Smith, T. P. L., Charoonpatrapong, K., Sloop, K. W., Bidwell, J. P. & Rhodes, S. J., Jul 21 2004, In : Gene. 336, 2, p. 263-273 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Nmp4/CIZ regulation of matrix metalloproteinase 13 (MMP-13) response to parathyroid hormone in osteoblasts

Shah, R., Alvarez, M., Jones, D. R., Torrungruang, K., Watt, A. J., Selvamurugan, N., Partridge, N. C., Quinn, C. O., Pavalko, F. M., Rhodes, S. J. & Bidwell, J. P., Aug 1 2004, In : American Journal of Physiology - Endocrinology and Metabolism. 287, 2 50-2, p. E289-E296

Research output: Contribution to journalArticle

35 Scopus citations

Regulation of the follicle-stimulating hormone β gene by the LHX3 LIM-homeodomain transcription factor

West, B. E., Parker, G. E., Savage, J. J., Kiratipranon, P., Toomey, K. S., Beach, L. R., Colvin, S. C., Sloop, K. W. & Rhodes, S. J., Nov 2004, In : Endocrinology. 145, 11, p. 4866-4879 14 p.

Research output: Contribution to journalArticle

79 Scopus citations
2003

Context-dependent transcription: All politics is local

Alvarez, M., Rhodes, S. J. & Bidwell, J. P., Aug 14 2003, In : Gene. 313, 1-2, p. 43-57 15 p.

Research output: Contribution to journalReview article

57 Scopus citations

Identification of biological relationships from text documents using efficient computational methods.

Palakal, M., Stephens, M., Mukhopadhyay, S., Raje, R. & Rhodes, S., Jul 2003, In : Journal of bioinformatics and computational biology. 1, 2, p. 307-342 36 p.

Research output: Contribution to journalArticle

21 Scopus citations

Severe short stature and endogenous growth hormone resistance in twin brothers without growth hormone gene mutations

Walvoord, E. C., Sloop, K. W., Dwyer, C. J., Rhodes, S. J. & Pescovitz, O. H., Aug 1 2003, In : Endocrine. 21, 3, p. 289-295 7 p.

Research output: Contribution to journalArticle

Transcriptional control during mammalian anterior pituitary development

Savage, J. J., Yaden, B. C., Kiratipranon, P. & Rhodes, S. J., Nov 13 2003, In : Gene. 319, 1-2, p. 1-19 19 p.

Research output: Contribution to journalReview article

107 Scopus citations
2002

A multi-level text mining method to extract biological relationships.

Palakal, M., Stephens, M., Mukhopadhyay, S., Raje, R. & Rhodes, S., 2002, In : Proceedings / IEEE Computer Society Bioinformatics Conference. IEEE Computer Society Bioinformatics Conference. 1, p. 97-108 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Differential conservation of transcriptional domains of mammalian Prophet of Pit-1 proteins revealed by structural studies of the bovine gene and comparative functional analysis of the protein

Showalter, A. D., Smith, T. P. L., Bennett, G. L., Sloop, K. W., Whitsett, J. A. & Rhodes, S. J., May 29 2002, In : Gene. 291, 1-2, p. 211-221 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

DNA binding and gene activation properties of the Nmp4 nuclear matrix transcription factors

Torrungruang, K., Alvarez, M., Shah, R., Onyia, J. E., Rhodes, S. J. & Bidwell, J. P., May 3 2002, In : Journal of Biological Chemistry. 277, 18, p. 16153-16159 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Genetic defects in the development and function of the anterior pituitary gland

Cushman, L. J., Showalter, A. D. & Rhodes, S. J., Jan 1 2002, In : Annals of Medicine. 34, 3, p. 179-191 13 p.

Research output: Contribution to journalReview article

46 Scopus citations

Identification of the single base change causing the callipyge muscle hypertrophy phenotype, the only known example of polar overdominance in mammals

Freking, B. A., Murphy, S. K., Wylie, A. A., Rhodes, S. J., Keele, J. W., Leymaster, K. A., Jirtle, R. L. & Smith, T. P. L., Oct 1 2002, In : Genome research. 12, 10, p. 1496-1506 11 p.

Research output: Contribution to journalArticle

175 Scopus citations

Osteoblast intracellular localization of Nmp4 proteins

Torrungruang, K., Shah, R., Alvarez, M., Bowen, D. K., Gerard, R., Pavalko, F. M., Elmendorf, J. S., Charoonpatrapong, K., Hock, J., Rhodes, S. J. & Bidwell, J. P., Jun 20 2002, In : Bone. 30, 6, p. 931-936 6 p.

Research output: Contribution to journalArticle

7 Scopus citations
2001
50 Scopus citations

Are your cells pregnant: Relating biology laboratory exercises to everyday life

Rhodes, S. J. & Banner, L. R., Sep 2001, In : American Biology Teacher. 63, 7, p. 514-517 4 p.

Research output: Contribution to journalArticle

Assignment of Nmp4 to mouse chromosome 6 band F1 flanked by D6Mit134 and D6Mit255 using radiation hybrid mapping and fluorescence in situ hybridization

Alvarez, M. B., Thunyakitpisal, P., Rhodes, S. J., Everett, E. T. & Bidwell, J. P., Dec 1 2001, In : Cytogenetics and Cell Genetics. 94, 3-4, p. 244-245 2 p.

Research output: Contribution to journalArticle

6 Scopus citations

Characterization and imaging of A6 epithelial cell clones expressing fluorescently labeled ENaC subunits

Blazer-Yost, B. L., Butterworth, M., Hartman, A. D., Parker, G. E., Faletti, C. J., Els, W. J. & Rhodes, S. J., 2001, In : American Journal of Physiology - Cell Physiology. 281, 2 50-2, p. C624-C632

Research output: Contribution to journalArticle

22 Scopus citations