Subbiah Sivam

  • 1435 Citations
  • 23 h-Index
1978 …2008
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Publications 1978 2008

  • 1435 Citations
  • 23 h-Index
  • 59 Article
  • 1 Conference contribution
1978
6 Citations (Scopus)

Metoprolol: a new cardioselective beta adrenoceptor antagonist in experimental cardiac arrhythmias

Sivam, S. & Seth, S. D., 1978, In : Indian Journal of Medical Research. 68, 1, p. 176-182 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Nature of antagonism of centrogenic ouabain arrhythmias by propranolol

Sivam, S., Seth, S. D. S., Nayer, U. & Manchanda, S. C., 1978, In : Journal of Molecular and Cellular Cardiology. 10, SUPPL.1, p. 111 1 p.

Research output: Contribution to journalArticle

1979

The problem of unauthentic drugs in India

Sivam, S., 1979, In : Annals of the National Academy of Medical Sciences (India). 15, 1, p. 35-42 8 p.

Research output: Contribution to journalArticle

India
Pharmaceutical Preparations
1980
2 Citations (Scopus)

Neurally induced digitalis arrhythmias and adrenoreceptors

Sivam, S., Seth, S. D., Nayar, U. & Manchanda, S. C., 1980, In : European Journal of Pharmacology. 68, 2, p. 107-115 9 p.

Research output: Contribution to journalArticle

Digitalis
Cardiac Arrhythmias
Ouabain
Tachycardia
Blood Vessels
1981
22 Citations (Scopus)

Alterations of regional γ-aminobutyric acid receptors in morphine tolerant mice

Sivam, S., Nabeshima, T. & Ho, I. K., Aug 1 1981, In : Biochemical Pharmacology. 30, 15, p. 2187-2190 4 p.

Research output: Contribution to journalArticle

Muscimol
GABA Receptors
Cell Surface Receptors
GABA-A Receptors
Morphine

Anticholinesterase effect of sotalol

Alkondon, M., Sivam, S., Bhatia, S. & Sen, P., 1981, In : Indian Journal of Medical Research. 73, 5, p. 796-800 5 p.

Research output: Contribution to journalArticle

Practolol
Ranidae
Sotalol
Abdominal Muscles
Physostigmine
20 Citations (Scopus)

Calcium-dependent GABA release from mouse brain slices following acute and chronic phencyclidine administration

Nabeshima, T., Sivam, S., Norris, J. C. & Ho, I. K., 1981, In : Research Communications in Substances of Abuse. 2, 4, p. 343-354 12 p.

Research output: Contribution to journalArticle

Phencyclidine
gamma-Aminobutyric Acid
Calcium
Brain
Corpus Striatum
2 Citations (Scopus)
Posterior Hypothalamus
Blood pressure
Microinjections
Ouabain
Electric Stimulation
5 Citations (Scopus)

Effects of acute and continuous administration of pentobarbital on phencyclidine response

Tai, C. Y., Nabeshima, T., Sivam, S. & Ho, I. K., 1981, In : Research Communications in Substances of Abuse. 2, 3, p. 239-252 14 p.

Research output: Contribution to journalArticle

Phencyclidine
Pentobarbital
Ataxia
Brain
Serum
1982
41 Citations (Scopus)

Acute and chronic effects of pentobarbital in relation to postsynaptic GABA receptors: A study with muscimol

Sivam, S., Nabeshima, T. & Ho, I. K., 1982, In : Journal of Neuroscience Research. 7, 1, p. 37-47 11 p.

Research output: Contribution to journalArticle

Muscimol
Pentobarbital
GABA-A Receptors
Picrotoxin
GABA Receptors
12 Citations (Scopus)
Opiate Alkaloids
Morphine
Binding Sites
Synaptic Membranes
Membranes
29 Citations (Scopus)

An analysis of GABA receptor changes in the discrete regions of mouse brain after acute and chronic treatments with morphine

Sivam, S., Nabeshima, T. & Ho, I. K., 1982, In : Journal of Neurochemistry. 39, 4, p. 933-939 7 p.

Research output: Contribution to journalArticle

Muscimol
GABA Receptors
Cell Surface Receptors
GABA-A Receptors
Morphine
23 Citations (Scopus)

Development of dispositional tolerance to phencyclidine by osmotic minipump in the mouse

Toshitaka, N., Sivam, S., Tai, C. Y. & Ho, I. K., 1982, In : Journal of Pharmacological Methods. 7, 3, p. 239-253 15 p.

Research output: Contribution to journalArticle

Phencyclidine
Ataxia
Cytochromes b5
Inbred ICR Mouse
Phosphoric Monoester Hydrolases
21 Citations (Scopus)

Influence of morphine dependence on GABA-stimulated benzodiazepine binding to mouse brain synaptic membranes

Sivam, S. & Ho, I. K., Apr 23 1982, In : European Journal of Pharmacology. 79, 3-4, p. 335-336 2 p.

Research output: Contribution to journalArticle

Morphine Dependence
Drug Receptors
Flunitrazepam
Synaptic Membranes
Inbred ICR Mouse
4 Citations (Scopus)

Interaction of ouabain and propranolol in the central nervous system. Neurally-mediated effects on the cardiovascular system

Sivam, S., Seth, S. D., Nayar, U. & Manchanda, S. C., 1982, In : Pharmacology. 25, 5, p. 286-293 8 p.

Research output: Contribution to journalArticle

Ouabain
Cardiovascular System
Propranolol
Central Nervous System
Local Anesthetics
Opioid Receptors
Morphine
1983
17 Citations (Scopus)

Diisopropylfluorophosphate and GABA synaptic function: Effect on levels, enzymes, release and uptake in the rat striatum

Sivam, S., Nabeshima, T., Lim, D. K., Hoskins, B. & Ho, I. K., 1983, In : Research Communications in Chemical Pathology and Pharmacology. 42, 1, p. 51-60 10 p.

Research output: Contribution to journalArticle

Isoflurophate
gamma-Aminobutyric Acid
Rats
Enzymes
4-Aminobutyrate Transaminase
90 Citations (Scopus)

Effect of acute and chronic cholinesterase inhibition with diisopropylfluorophosphate on muscarinic, dopamine, and GABA receptors of the rat striatum

Sivam, S., Norris, J. C., Lim, D. K., Hoskins, B. & Ho, I. K., 1983, In : Journal of Neurochemistry. 40, 5, p. 1414-1422 9 p.

Research output: Contribution to journalArticle

Isoflurophate
GABA Receptors
Cholinesterases
Dopamine Receptors
Muscarinic Receptors
17 Citations (Scopus)
Phencyclidine
Morphine
Opiate Alkaloids
Liver
Aniline Hydroxylase
36 Citations (Scopus)

Gabaergic drugs, morphine and morphine tolerance: A study in relation to nociception and gastrointestinal transit in mice

Sivam, S. & Ho, I. K., 1983, In : Neuropharmacology. 22, 6, p. 767-774 8 p.

Research output: Contribution to journalArticle

Gastrointestinal Transit
Nociception
Morphine
Pharmaceutical Preparations
Muscimol

Mechanism of tolerance development to pentobarbital in relation to GABA-ergic neuronal and dispositional functions in mice

Nabeshima, T., Kameyama, T., Sivam, S. & Ho, I. K., 1983, In : Journal of Pharmacobio-Dynamics. 6, 3

Research output: Contribution to journalArticle

1984

Acute toxicity of Soman, Sarin and Tabun: Neurochemical evaluations related to cholinergic, GABAergic and dopamine systems

Sivam, S., Lim, D. K., Hoskins, B. & Ho, I. K., 1984, In : Federation Proceedings. 43, 3

Research output: Contribution to journalArticle

Sarin
Soman
Cholinergic Agents
Dopamine
tabun
9 Citations (Scopus)

Analgesic cross-tolerance between morphine and opioid peptides

Sivam, S. & Ho, I. K., Sep 1984, In : Psychopharmacology. 84, 1, p. 64-65 2 p.

Research output: Contribution to journalArticle

Opioid Peptides
Morphine
Analgesics
Endorphins
Leucine-2-Alanine Enkephalin
46 Citations (Scopus)
fluorophosphate
Sarin
Soman
Enzyme activity
Acetylcholinesterase
2 Citations (Scopus)
Opiate Alkaloids
delta Opioid Receptor
mu Opioid Receptor
Analgesia
Morphine
7 Citations (Scopus)

Attenuation of pharmacological effects and increased metabolism of phencyclidine in morphine tolerant mice

Nabeshima, T., Sivam, S. & Ho, I. K., Sep 17 1984, In : European Journal of Pharmacology. 104, 3-4, p. 211-221 11 p.

Research output: Contribution to journalArticle

Phencyclidine
Morphine
Pharmacology
Locomotion
Ataxia
7 Citations (Scopus)

Roles of dopamine and GABA in neurotoxicity of organophosphorus cholinesterase inhibitors

Ho, I. K., Fernando, J. C. R., Sivam, S. & Hoskins, B., 1984, In : Proceedings of the Western Pharmacology Society. VOL. 27, p. 177-180 4 p.

Research output: Contribution to journalArticle

Parasympathetic Nervous System
Organophosphorus Compounds
Isoflurophate
Cholinesterase Inhibitors
Nervous System Diseases
1985
54 Citations (Scopus)

GABA in morphine analgesia and tolerance

Sivam, S. & Ho, I. K., Jul 22 1985, In : Life Sciences. 37, 3, p. 199-208 10 p.

Research output: Contribution to journalArticle

Opiate Alkaloids
Analgesia
gamma-Aminobutyric Acid
Morphine
Analgesics
1986
9 Citations (Scopus)

Dopaminergic regulation of proenkephalin-A gene expression in the basal ganglia.

Sivam, S., Breese, G. R., Napier, T. C., Mueller, R. A. & Hong, J. S., 1986, In : NIDA research monograph. 75, p. 389-392 4 p.

Research output: Contribution to journalArticle

Enkephalins
Basal Ganglia
Gene Expression
Oxidopamine
Corpus Striatum
27 Citations (Scopus)
Enkephalins
gamma-Aminobutyric Acid
Messenger RNA
Aminooxyacetic Acid
Brain
56 Citations (Scopus)

Proenkephalin-A gene regulation in the rat striatum: Influence of lithium and haloperidol

Sivam, S., Strunk, C., Smith, D. R. & Hong, J. S., 1986, In : Molecular Pharmacology. 30, 2, p. 186-191 6 p.

Research output: Contribution to journalArticle

Haloperidol
Enkephalins
Lithium
Genes
Messenger RNA
65 Citations (Scopus)

Regulation of the concentration of dynorphin A1-8 in the striatonigral pathway by the dopaminergic system

Li, S., Sivam, S. & Hong, J. S., Nov 29 1986, In : Brain Research. 398, 2, p. 390-392 3 p.

Research output: Contribution to journalArticle

Dynorphins
Apomorphine
Substantia Nigra
Corpus Striatum
Injections
1987
52 Citations (Scopus)

Dopaminergic regulation of tachykinin metabolism in the striatonigral pathway

Li, S. J., Sivam, S., McGinty, J. F., Huang, Y. S. & Hong, J. S., 1987, In : Journal of Pharmacology and Experimental Therapeutics. 243, 2, p. 792-798 7 p.

Research output: Contribution to journalArticle

Tachykinins
Neurokinin A
Corpus Striatum
Dopamine Receptors
Substantia Nigra
10 Citations (Scopus)

GABA and dopamine interaction in the basal ganglia: dopaminergic supersensitivity following chronic elevation of brain γ-aminobutyric acid levels

Sivam, S., Hudson, P. M., Tilson, H. A. & Hong, J. S., May 26 1987, In : Brain Research. 412, 1, p. 29-35 7 p.

Research output: Contribution to journalArticle

Aminobutyrates
Basal Ganglia
gamma-Aminobutyric Acid
Dopamine
Aminooxyacetic Acid
16 Citations (Scopus)

Lithium and haloperidol differentially alter the dynorphin A (1-8) and enkephalin levels in the neurointermediate lobe of rat pituitary

Sivam, S., Smith, D. R., Takeuchi, K. & Hong, J. S., 1987, In : Neuropeptides. 10, 3, p. 291-298 8 p.

Research output: Contribution to journalArticle

dynorphin (1-8)
Enkephalins
Haloperidol
Lithium
Rats
111 Citations (Scopus)

Neonatal and adult 6-hydroxydopamine-induced lesions differentially alter tachykinin and enkephalin gene expression

Sivam, S., Breese, G. R., Krause, J. E., Napier, T. C., Mueller, R. A. & Hong, J. S., 1987, In : Journal of Neurochemistry. 49, 5, p. 1623-1633 11 p.

Research output: Contribution to journalArticle

Tachykinins
Enkephalins
Oxidopamine
Gene expression
Rats
1988
2 Citations (Scopus)

Effects and mechanism of action of lithium chloride on gastric acid secretion in rats

Guglietta, A., Irons, B. J., Lazarus, L. H. & Sivam, S., 1988, In : Gastroenterology. 95, 6, p. 1454-1459 6 p.

Research output: Contribution to journalArticle

Lithium Chloride
Gastric Acid
Lithium
Stomach
Opioid Receptors
35 Citations (Scopus)

Lithium increases dynorphin A(1-8) and prodynorphin mRNA levels in the basal ganglia of rats

Sivam, S., Takeuchi, K., Li, S., Douglass, J., Civelli, O., Calvetta, L., Herbert, E., McGinty, J. F. & Hong, J. S., 1988, In : Molecular Brain Research. 3, 2, p. 155-163 9 p.

Research output: Contribution to journalArticle

dynorphin (1-8)
Basal Ganglia
Lithium
Messenger RNA
Haloperidol
87 Citations (Scopus)

Regulation of the metabolism of striatal dynorphin by the dopaminergic system

Li, S. J., Sivam, S., McGinty, J. F., Jiang, H. K., Douglass, J., Calavetta, L. & Hong, J. S., 1988, In : Journal of Pharmacology and Experimental Therapeutics. 246, 1, p. 403-408 6 p.

Research output: Contribution to journalArticle

Corpus Striatum
Dynorphins
Injections
dynorphin (1-8)
Neurons
1989
148 Citations (Scopus)
Dynorphins
Cocaine
Enkephalins
Corpus Striatum
Dopamine
36 Citations (Scopus)
Self-Injurious Behavior
Dopamine D1 Receptors
Denervation
Substance P
Oxidopamine
35 Citations (Scopus)

Lithium increases rat striatal beta- and gamma-preprotachykinin messenger RNAs

Sivam, S., Krause, J. E., Takeuchi, K., Li, S., McGinty, J. F. & Hong, J. S., 1989, In : Journal of Pharmacology and Experimental Therapeutics. 248, 3, p. 1297-1301 5 p.

Research output: Contribution to journalArticle

Corpus Striatum
Lithium
Messenger RNA
Substance P
Haloperidol
1990
14 Citations (Scopus)
Dihydroxyphenylalanine
Dopaminergic Neurons
Substance P
Messenger RNA
Oxidopamine

Deprenyl increases striatal enkephalin levels and preproenkephalin mRNA abundance

Sivam, S., 1990, New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914. Van Ree, J. M., Mulder, A. H., Wiegant, V. M., Van Wimersma Greidanus, T. B., Van Ree, J. M., Mulder, A. H., Wiegant, V. M. & Van Wimersma Greidanus, T. B. (eds.). Elsevier Science Publishers B.V., p. 357 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Selegiline
Corpus Striatum
Methionine Enkephalin
Enkephalins
Clorgyline
Tachykinins
Enkephalins
Denervation
Basal Ganglia
24 Citations (Scopus)
Tachykinins
Enkephalins
Denervation
Basal Ganglia
Dopamine
1991
39 Citations (Scopus)
Enkephalins
Substance P
Basal Ganglia
Dopamine
Brain
33 Citations (Scopus)

Dopamine-dependent postnatal development of enkephalin and tachykinin neurons of rat basal ganglia

Sivam, S., Krause, J. E., Breese, G. R. & Hong, J. S., May 1991, In : Journal of Neurochemistry. 56, 5, p. 1499-1508 10 p.

Research output: Contribution to journalArticle

Tachykinins
Enkephalins
Basal Ganglia
Neurons
Rats
1992
Neuropeptides
Cysteine
Neurotransmitter Agents
Rats
dynorphin (1-8)
27 Citations (Scopus)
Neurokinin-1 Receptors
Tachykinins
Capsaicin
Spinal Ganglia
Substance P