Tatiana Foroud

  • 42200 Citations
  • 101 h-Index
1976 …2021
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Publications 1988 2020

2015
100 Citations (Scopus)

Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE

Alzheimer's Disease Neuroimaging Initiative, May 19 2015, In : Nature Communications. 6, 6760.

Research output: Contribution to journalArticle

cerebrospinal fluid
Cerebrospinal fluid
Ferritins
Cerebrospinal Fluid
Alzheimer Disease
5 Citations (Scopus)

Fine mapping of bone structure and strength QTLs in heterogeneous stock rat

Alam, I., Koller, D. L., Cañete, T., Blázquez, G., Mont-Cardona, C., López-Aumatell, R., Martínez-Membrives, E., Díaz-Morán, S., Tobeña, A., Fernández-Teruel, A., Stridh, P., Diez, M., Olsson, T., Johannesson, M., Baud, A., Econs, M. & Foroud, T., Dec 1 2015, In : Bone. 81, p. 417-426 10 p., 10840.

Research output: Contribution to journalArticle

Quantitative Trait Loci
Femur Neck
Phenotype
Bone and Bones
Haplotypes
6 Citations (Scopus)

Genes associated with alcohol outcomes show enrichment of effects with broad externalizing and impulsivity phenotypes in an independent sample

Aliev, F., Wetherill, L., Bierut, L., Bucholz, K. K., Edenberg, H., Foroud, T., Investigators, C. & Xuei, X., Jan 1 2015, In : Journal of Studies on Alcohol and Drugs. 76, 1, p. 38-46 9 p.

Research output: Contribution to journalArticle

Impulsive Behavior
Genes
Polymorphism
alcohol
Alcohols
19 Citations (Scopus)

Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses

Adult Changes in Thought Study Investigators, Religious Orders Study/Memory and Aging Project Investigators & Alzheimer's Disease Genetics Consortium, Dec 1 2015, In : Alzheimer's and Dementia. 11, 12, p. 1439-1451 13 p.

Research output: Contribution to journalArticle

Mendelian Randomization Analysis
Alzheimer Disease
Body Mass Index
Phenotype
Odds Ratio
5 Citations (Scopus)

Genetic influences on plasma homocysteine levels in African Americans and Yoruba Nigerians

Kim, S., Nho, K., Ramanan, V. K., Lai, D., Foroud, T., Lane, K., Murrell, J. R., Gao, S., Hall, K., Unverzagt, F., Baiyewu, O., Ogunniyi, A., Gureje, O., Kling, M. A., Doraiswamy, P. M., Kaddurah-Daouk, R., Hendrie, H. & Saykin, A., Dec 24 2015, In : Journal of Alzheimer's Disease. 49, 4, p. 991-1003 13 p.

Research output: Contribution to journalArticle

Homocysteine
African Americans
GABA Receptors
Dementia
Alzheimer Disease
1463 Citations (Scopus)

Genetic studies of body mass index yield new insights for obesity biology

Collaborators, LifeLines Cohort Study & ADIPOGen Consortium; AGEN-BMI Working Group; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GLGC; ICBP; MAGIC Investigators; MuTHER Consortium; MIGen Consortium; PAGE Consortium; ReproGen Consortium; GENIE Consortium; International Endogene Consortium, Feb 12 2015, In : Nature. 518, 7538, p. 197-206 10 p.

Research output: Contribution to journalArticle

Body Mass Index
Obesity
Adipogenesis
Genome-Wide Association Study
Adiposity
80 Citations (Scopus)

Genetic studies of quantitative MCI and AD phenotypes in ADNI: Progress, opportunities, and plans

Saykin, A., Shen, L., Yao, X., Kim, S., Nho, K., Risacher, S. L., Ramanan, V. K., Foroud, T., Faber, K. M., Sarwar, N., Munsie, L. M., Hu, X., Soares, H. D., Potkin, S. G., Thompson, P. M., Kauwe, J. S. K., Kaddurah-Daouk, R., Green, R. C., Toga, A. W. & Weiner, M. W., Jul 1 2015, In : Alzheimer's and Dementia. 11, 7, p. 792-814 23 p.

Research output: Contribution to journalArticle

Neuroimaging
Alzheimer Disease
Phenotype
Genome-Wide Association Study
Exome
5 Citations (Scopus)

Genetic variants associated with susceptibility to psychosis in late-onset Alzheimer's disease families

NIA-LOAD/NCRAD Family Study Group, Nov 1 2015, In : Neurobiology of Aging. 36, 11, p. 3116.e9-3116.e16

Research output: Contribution to journalArticle

Psychotic Disorders
Alzheimer Disease
Hispanic Americans
Brain
Genes
15 Citations (Scopus)

Genome-wide association data suggest ABCB1 and immune-related gene sets may be involved in adult antisocial behavior

Salvatore, J. E., Edwards, A. C., McClintick, J., Bigdeli, T. B., Adkins, A., Aliev, F., Edenberg, H., Foroud, T., Hesselbrock, V., Kramer, J., Nurnberger, J., Schuckit, M., Tischfield, J. A., Xuei, X. & Dick, D. M., Apr 28 2015, In : Translational Psychiatry. 5, 4, e558.

Research output: Contribution to journalArticle

Genome
Diagnostic and Statistical Manual of Mental Disorders
Genes
Alcoholism
Single Nucleotide Polymorphism
53 Citations (Scopus)

Genome-Wide Association Studies for Taxane-Induced Peripheral Neuropathy in ECOG-5103 and ECOG-1199

Schneider, B., Li, L., Radovich, M., Shen, F., Miller, K., Flockhart, D. A., Jiang, G., Vance, G., Gardner, L., Vatta, M., Bai, S., Lai, D., Koller, D., Zhao, F., O'Neill, A., Smith, M. L., Railey, E., White, C., Partridge, A., Sparano, J. & 3 others, Davidson, N. E., Foroud, T. & Sledge, G. W., Nov 15 2015, In : Clinical Cancer Research. 21, 22, p. 5082-5091 10 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Peripheral Nervous System Diseases
Single Nucleotide Polymorphism
taxane
Breast Neoplasms
54 Citations (Scopus)

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

Hou, L., Bergen, S. E., Akula, N., Song, J., Hultman, C. M., Landén, M., Adli, M., Alda, M., Ardau, R., Arias, B., Aubry, J. M., Backlund, L., Badner, J. A., Barrett, T. B., Bauer, M., Baune, B. T., Bellivier, F., Benabarre, A., Bengesser, S., Berrettini, W. H. & 119 others, Bhattacharjee, A. K., Biernacka, J. M., Birner, A., Bloss, C. S., Brichant-Petitjean, C., Bui, E. T., Byerley, W., Cervantes, P., Chillotti, C., Cichon, S., Colom, F., Coryell, W., Craig, D. W., Cruceanu, C., Czerski, P. M., Davis, T., Dayer, A., Degenhardt, F., Del Zompo, M., DePaulo, J. R., Edenberg, H., Étain, B., Falkai, P., Foroud, T., Forstner, A. J., Frisén, L., Frye, M. A., Fullerton, J. M., Gard, S., Garnham, J. S., Gershon, E. S., Goes, F. S., Greenwood, T. A., Grigoroiu-Serbanescu, M., Hauser, J., Heilbronner, U., Heilmann-Heimbach, S., Herms, S., Hipolito, M., Hitturlingappa, S., Hoffmann, P., Hofmann, A., Jamain, S., Jiménez, E., Kahn, J. P., Kassem, L., Kelsoe, J. R., Kittel-Schneider, S., Kliwicki, S., Koller, D. L., König, B., Lackner, N., Laje, G., Lang, M., Lavebratt, C., Lawson, W. B., Leboyer, M., Leckband, S. G., Liu, C., Maaser, A., Mahon, P. B., Maier, W., Maj, M., Manchia, M., Martinsson, L., McCarthy, M. J., McElroy, S. L., McInnis, M. G., McKinney, R., Mitchell, P. B., Mitjans, M., Mondimore, F. M., Monteleone, P., Mühleisen, T. W., Nievergelt, C. M., Nöthen, M. M., Novák, T., Nurnberger, J., Nwulia, E. A., Ösby, U., Pfennig, A., Potash, J. B., Propping, P., Reif, A., Reininghaus, E., Rice, J., Rietschel, M., Rouleau, G. A., Rybakowski, J. K., Schalling, M., Scheftner, W. A., Schofield, P. R., Schork, N. J., Schulze, T. G., Schumacher, J., Schweizer, B. W., Severino, G., Shekhtman, T., Shilling, P. D., Simhandl, C., Slaney, C. M., Smith, E. N., Squassina, A., Stamm, T., Stopkova, P., Streit, F., Strohmaier, J., Szelinger, S., Tighe, S. K., Tortorella, A., Turecki, G., Vieta, E., Volkert, J., Witt, S. H., Wright, A., Zandi, P. P., Zhang, P., Zollner, S. & McMahon, F. J., 2015, In : Human Molecular Genetics. 25, 15, p. 3383-3394 12 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Bipolar Disorder
X Chromosome
Lithium
Odds Ratio
8 Citations (Scopus)

Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk

Hohman, T. J., Cooke-Bailey, J. N., Reitz, C., Jun, G., Naj, A., Beecham, G. W., Liu, Z., Carney, R. M., Vance, J. M., Cuccaro, M. L., Rajbhandary, R., Vardarajan, B. N., Wang, L. S., Valladares, O., Lin, C. F., Larson, E. B., Graff-Radford, N. R., Evans, D., De Jager, P. L., Crane, P. K. & 33 others, Buxbaum, J. D., Murrell, J. R., Raj, T., Ertekin-Taner, N., Logue, M. W., Baldwin, C. T., Green, R. C., Barnes, L. L., Cantwell, L. B., Fallin, M. D., Go, R. C. P., Griffith, P., Obisesan, T. O., Manly, J. J., Lunetta, K. L., Kamboh, M. I., Lopez, O. L., Bennett, D. A., Hardy, J., Hendrie, H., Hall, K., Goate, A. M., Lang, R., Byrd, G. S., Kukull, W. A., Foroud, T., Farrer, L. A., Martin, E. R., Pericak-Vance, M. A., Schellenberg, G. D., Mayeux, R., Haines, J. L. & Thornton-Wells, T. A., 2015, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

African Americans
Alzheimer Disease
Genome-Wide Association Study
86 Citations (Scopus)

Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research

O'Bryant, S. E., Gupta, V., Henriksen, K., Edwards, M., Jeromin, A., Lista, S., Bazenet, C., Soares, H., Lovestone, S., Hampel, H., Montine, T., Blennow, K., Foroud, T., Carrillo, M., Graff-Radford, N., Laske, C., Breteler, M., Shaw, L., Trojanowski, J. Q., Schupf, N. & 8 others, Rissman, R. A., Fagan, A. M., Oberoi, P., Umek, R., Weiner, M. W., Grammas, P., Posner, H. & Martins, R., May 1 2015, In : Alzheimer's and Dementia. 11, 5, p. 549-560 12 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Biomarkers
Guidelines
Research
Neuroimaging
48 Citations (Scopus)

GWAS of longitudinal amyloid accumulation on 18F-florbetapir PET in Alzheimer's disease implicates microglial activation gene IL1RAP

Ramanan, V. K., Risacher, S. L., Nho, K., Kim, S., Shen, L., McDonald, B., Yoder, K., Hutchins, G., West, J. D., Tallman, E. F., Gao, S., Foroud, T., Farlow, M., De Jager, P. L., Bennett, D. A., Aisen, P. S., Petersen, R. C., Jack, C. R., Toga, A. W., Green, R. C. & 3 others, Jagust, W. J., Weiner, M. W. & Saykin, A., Oct 1 2015, In : Brain. 138, 10, p. 3076-3088 13 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Amyloid
Transcriptional Activation
Alzheimer Disease
Interleukin-1 Receptor Accessory Protein
34 Citations (Scopus)

Integrating mRNA and miRNA weighted gene co-expression networks with eQTLs in the nucleus accumbens of subjects with alcohol dependence

Mamdani, M., Williamson, V., McMichael, G. O., Blevins, T., Aliev, F., Adkins, A., Hack, L., Bigdeli, T., Van Der Vaart, A. D., Web, B. T., Bacanu, S. A., Kalsi, G., Kendler, K. S., Miles, M. F., Dick, D., Riley, B. P., Dumur, C., Vladimirov, V. I., Hesselbrock, V., Edenberg, H. & 29 others, Nurnberger, J., Foroud, T., Kuperman, S., Kramer, J., Porjesz, B., Bierut, L., Goate, A., Rice, J., Bucholz, K., Schuckit, M., Tischfield, J., Almasy, L., Taylor, R., Dick, D., Bauer, L., Koller, D., O'Connor, S., Wetherill, L., Xuei, X., Chan, G., Kang, S., Manz, N., Rangaswamy, M., Rohrbaugh, J., Wang, J. C., Brooks, A., Aliev, F., Parsian, A. & Reilly, M., Sep 18 2015, In : PLoS One. 10, 9, e0137671.

Research output: Contribution to journalArticle

Nucleus Accumbens
alcohol abuse
MicroRNAs
microRNA
Alcoholism
98 Citations (Scopus)

Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder

Cross-Disorder Working Group of the Psychiatric Genomics Consortium, Feb 5 2015, In : American Journal of Human Genetics. 96, 2, p. 283-294 12 p.

Research output: Contribution to journalArticle

Major Depressive Disorder
Bipolar Disorder
Psychiatry
Schizophrenia
Sample Size
20 Citations (Scopus)

Large-scale genomics unveil polygenic architecture of human cortical surface area

Chen, C. H., Peng, Q., Schork, A. J., Lo, M. T., Fan, C. C., Wang, Y., Desikan, R. S., Bettella, F., Hagler, D. J., Westlye, L. T., Kremen, W. S., Jernigan, T. L., Le Hellard, S., Steen, V. M., Espeseth, T., Huentelman, M., Håberg, A. K., Agartz, I., Djurovic, S., Andreassen, O. A. & 86 others, Schork, N., Dale, A. M., McCabe, C., Chang, L., Akshoomoff, N., Newman, E., Ernst, T., Van Zijl, P., Kuperman, J., Murray, S., Bloss, C., Appelbaum, M., Gamst, A., Thompson, W., Bartsch, H., Weiner, M., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A., Morris, J., Shaw, L. M., Khachaturian, Z., Sorensen, G., Carrillo, M., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulman, M. M., Potter, W., Snyder, P. J., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., DeCarli, C., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Landau, S., Cairns, N. J., Householder, E., Taylor-Reinwald, L., Lee, V. M. Y., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T., Potkin, S., Shen, L., Faber, K., Kim, S., Nho, K., Thal, L., Frank, R., Buckholtz, N., Albert, M. & Hsiao, J., Jul 20 2015, In : Nature Communications. 6, 7549.

Research output: Contribution to journalArticle

polymorphism
nucleotides
Genomics
Polymorphism
Single Nucleotide Polymorphism
20 Citations (Scopus)

Lessons learned from whole exome sequencing in multiplex families affected by a complex genetic disorder, intracranial aneurysm

Farlow, J. L., Lin, H., Sauerbeck, L., Lai, D., Koller, D. L., Pugh, E., Hetrick, K., Ling, H., Kleinloog, R., Van Der Vlies, P., Deelen, P., Swertz, M. A., Verweij, B. H., Regli, L., Rinkel, G. J. E., Ruigrok, Y. M., Doheny, K., Liu, Y., Foroud, T., Broderick, J. & 59 others, Woo, D., Kissela, B., Kleindorfer, D., Schneider, A., Zuccarello, M., Ringer, A., Deka, R., Brown, R. D., Huston, J., Mesissner, I., Wiebers, D., Qureshi, A. I., Rasmussen, P. A., Connolly, E. S., Sacco, R. L., Malkaff, M., Payner, T. D., Ferguson, G. G., Aldrich, E. F., Rouleau, G., Anderson, C. S., Mee, E. W., Hankey, G. J., Knuckey, N., Reilly, P. L., Laidlaw, J. D., D'Urso, P., Rosenfeld, J. V., Morgan, M. K., Dorsch, N., Besser, M., Batjer, H. H., Richard, M. T., Kassam, A., Steinberg, G. K., Johnston, S. C., Ko, N. U., Giannotta, S. L., Kassell, N. F., Worrall, B. B., Lui, K. C., Dumont, A., Tirschell, D. L., Kaufmann, A. M., Fisher, W. S., Aziz, K. M. A., Day, A. L., Du, R., Ogilvy, C., Lewis, S. B., Murphy, K. P., Radvany, M., Gandhi, D., Lisabeth, L., Pandey, A., Morgenstern, L., Derdeyn, C., Langefeld, C. & Bailey-Wilson, J., Mar 24 2015, In : PLoS One. 10, 3, e0121104.

Research output: Contribution to journalArticle

Exome
aneurysm
Inborn Genetic Diseases
Intracranial Aneurysm
genetic disorders
14 Citations (Scopus)

Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease

Barral, S., Cheng, R., Reitz, C., Vardarajan, B., Lee, J., Kunkle, B., Beecham, G., Cantwell, L. S., Pericak-Vance, M. A., Farrer, L. A., Haines, J. L., Goate, A. M., Foroud, T., Boerwinkle, E., Schellenberg, G. D. & Mayeux, R., Dec 1 2015, In : Alzheimer's and Dementia. 11, 12, p. 1397-1406 10 p.

Research output: Contribution to journalArticle

Hispanic Americans
Alzheimer Disease
Multigene Family
Nervous System
Joints
516 Citations (Scopus)

New genetic loci link adipose and insulin biology to body fat distribution

Collaborators & ADIPOGen Consortium; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GEFOS Consortium; GENIE Consortium; GLGC; ICBP; International Endogene Consortium; LifeLines Cohort Study; MAGIC Investigators; MuTHER Consortium; PAGE Consortium; ReproGen Consortium, Feb 12 2015, In : Nature. 518, 7538, p. 187-196 10 p.

Research output: Contribution to journalArticle

Body Fat Distribution
Genetic Loci
Waist-Hip Ratio
Waist Circumference
Hip
5 Citations (Scopus)

Novel recruitment strategy to enrich for lrrk2 mutation carriers

Foroud, T., Smith, D., Jackson, J., Verbrugge, J., Halter, C., Wetherill, L., Sims, K., Xin, W., Arnedo, V., Lasch, S. & Marek, K., Jan 1 2015, In : Molecular Genetics and Genomic Medicine. 3, 5, p. 404-412 9 p.

Research output: Contribution to journalArticle

Open Access
Mutation
Parkinson Disease
Internet
Biomarkers
Clinical Trials
27 Citations (Scopus)

PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease

Beecham, G. W., Dickson, D. W., Scott, W. K., Martin, E. R., Schellenberg, G., Nuytemans, K., Larson, E. B., Buxbaum, J. D., Trojanowski, J. Q., Van Deerlin, V. M., Hurtig, H. I., Mash, D. C., Beach, T. G., Troncoso, J. C., Pletnikova, O., Frosch, M. P., Ghetti, B., Foroud, T., Honig, L. S., Marder, K. & 12 others, Vonsattel, J. P., Goldman, S. M., Vinters, H. V., Ross, O. A., Wszolek, Z. K., Wang, L., Dykxhoorn, D. M., Pericak-Vance, M. A., Montine, T. J., Leverenz, J. B., Dawson, T. M. & Vance, J. M., Mar 10 2015, In : Neurology. 84, 10, p. 972-980 9 p.

Research output: Contribution to journalArticle

Parkinson Disease
Genome-Wide Association Study
Haplotypes
Genetic Heterogeneity
Chromosomes, Human, Pair 1
47 Citations (Scopus)

Peroxisome Proliferator-Activated Receptors α and γ are Linked with Alcohol Consumption in Mice and Withdrawal and Dependence in Humans

Blednov, Y. A., Benavidez, J. M., Black, M., Ferguson, L. B., Schoenhard, G. L., Goate, A. M., Edenberg, H., Wetherill, L., Hesselbrock, V., Foroud, T. & Adron Harris, R., Jan 1 2015, In : Alcoholism: Clinical and Experimental Research. 39, 1, p. 136-145 10 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Alcohol Drinking
Alcohols
Alcoholism
Association reactions
46 Citations (Scopus)

Polygenic Risk for Externalizing Disorders: Gene-by-Development and Gene-by-Environment Effects in Adolescents and Young Adults

Salvatore, J. E., Aliev, F., Bucholz, K., Agrawal, A., Hesselbrock, V., Hesselbrock, M., Bauer, L., Kuperman, S., Schuckit, M. A., Kramer, J. R., Edenberg, H., Foroud, T. & Dick, D. M., Mar 1 2015, In : Clinical Psychological Science. 3, 2, p. 189-201 13 p.

Research output: Contribution to journalArticle

Young Adult
Impulsive Behavior
Genes
Psychopathology
Genome-Wide Association Study
32 Citations (Scopus)

Protective variant for hippocampal atrophy identified by whole exome sequencing

Nho, K., Kim, S., Risacher, S. L., Shen, L., Corneveaux, J. J., Swaminathan, S., Lin, H., Ramanan, V. K., Liu, Y., Foroud, T., Inlow, M. H., Siniard, A. L., Reiman, R. A., Aisen, P. S., Petersen, R. C., Green, R. C., Jack, C. R., Weiner, M. W., Baldwin, C. T., Lunetta, K. L. & 14 others, Farrer, L. A., Furney, S. J., Lovestone, S., Simmons, A., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., McDonald, B., Farlow, M., Ghetti, B., Huentelman, M. J. & Saykin, A., Mar 1 2015, In : Annals of Neurology. 77, 3, p. 547-552 6 p.

Research output: Contribution to journalArticle

Exome
Neurogenesis
Neuroimaging
Computer Simulation
Atrophy
361 Citations (Scopus)

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

The Network and Pathway Analysis Subgroup of the Psychiatric Genomics Consortium & International Inflammatory Bowel Disease Genetics Consortium (IIBDGC), Feb 17 2015, In : Nature Neuroscience. 18, 2, p. 199-209 11 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Histones
Psychiatry
Post-Synaptic Density
Genomics
20 Citations (Scopus)

Rarity of the alzheimer disease-protective APP A673T variant in the United States

National Institute on Aging-Late-Onset Alzheimer's Disease (NIA-LOAD) Family Study & Alzheimer's Disease Genetics Consortium, Feb 1 2015, In : JAMA Neurology. 72, 2, p. 209-216 8 p.

Research output: Contribution to journalArticle

Amyloid beta-Protein Precursor
Alzheimer Disease
Genes
Sweden
Alanine
6 Citations (Scopus)

Steroid Pathway Genes and Neonatal Respiratory Distress after Betamethasone Use in Anticipated Preterm Birth

Haas, D., Lai, D., Sharma, S., Then, J., Kho, A., Flockhart, D. A., Tantisira, K. & Foroud, T., 2015, In : Reproductive Sciences. 23, 5, p. 680-686 7 p.

Research output: Contribution to journalArticle

Betamethasone
Premature Birth
Single Nucleotide Polymorphism
Steroids
Mothers
66 Citations (Scopus)

TREM2 is associated with increased risk for Alzheimer's disease in African Americans

Jin, S. C., Carrasquillo, M. M., Benitez, B. A., Skorupa, T., Carrell, D., Patel, D., Lincoln, S., Krishnan, S., Kachadoorian, M., Reitz, C., Mayeux, R., Wingo, T. S., Lah, J. J., Levey, A. I., Murrell, J., Hendrie, H., Foroud, T., Graff-Radford, N. R., Goate, A. M., Cruchaga, C. & 1 others, Ertekin-Taner, N., Apr 10 2015, In : Molecular Neurodegeneration. 10, 1, 19.

Research output: Contribution to journalArticle

African Americans
Alzheimer Disease
Linkage Disequilibrium
Myeloid Cells
Mutation
2014
18 Citations (Scopus)

Absence of C9ORF72 expanded or intermediate repeats in autopsy-confirmed Parkinson's disease

Nuytemans, K., Inchausti, V., Beecham, G. W., Wang, L., Dickson, D. W., Trojanowski, J. Q., Lee, V. M. Y., Mash, D. C., Frosch, M. P., Foroud, T., Honig, L. S., Montine, T. J., Dawson, T. M., Martin, E. R., Scott, W. K. & Vance, J. M., 2014, In : Movement Disorders. 29, 6, p. 827-830 4 p.

Research output: Contribution to journalArticle

Parkinson Disease
Autopsy
Haplotypes
Parkinsonian Disorders
Neurodegenerative Diseases
25 Citations (Scopus)

Age-specific incidence rates for dementia and alzheimer disease in NIA-LOAD/NCRAD and EFIGA families: National Institute on Aging Genetics Initiative for late-onset Alzheimer disease/National Cell Repository for Alzheimer disease (NIA-LOAD/NCRAD) and Estudio Familiar de Influencia Genetica en Alzheimer (EFIGA)

Vardarajan, B. N., Faber, K. M., Bird, T. D., Bennett, D. A., Rosenberg, R., Boeve, B. F., Graff-Radford, N. R., Goate, A. M., Farlow, M., Sweet, R. A., Lantigua, R., Medrano, M. Z., Ottman, R., Schaid, D. J., Foroud, T. & Mayeux, R., 2014, In : JAMA Neurology. 71, 3, p. 315-323 9 p.

Research output: Contribution to journalArticle

National Institute on Aging (U.S.)
Dementia
Alzheimer Disease
Incidence
Onset
14 Citations (Scopus)

Alcohol-preferring rats show decreased corticotropin-releasing hormone-2 receptor expression and differences in hpa activation compared to alcohol-nonpreferring rats

Yong, W., Spence, J. P., Eskay, R., Fitz, S. D., Damadzic, R., Lai, D., Foroud, T., Carr, L. G., Shekhar, A., Chester, J. A., Heilig, M. & Liang, T., 2014, In : Alcoholism: Clinical and Experimental Research. 38, 5, p. 1275-1283 9 p.

Research output: Contribution to journalArticle

Corticotropin-Releasing Hormone Receptors
Corticotropin-Releasing Hormone
Rats
Chemical activation
Alcohols
23 Citations (Scopus)

An ADH1B variant and peer drinking in progression to adolescent drinking milestones: Evidence of a gene-by-environment interaction

Olfson, E., Edenberg, H., Nurnberger, J., Agrawal, A., Bucholz, K. K., Almasy, L. A., Chorlian, D., Dick, D. M., Hesselbrock, V. M., Kramer, J. R., Kuperman, S., Porjesz, B., Schuckit, M. A., Tischfield, J. A., Wang, J. C., Wetherill, L., Foroud, T., Rice, J., Goate, A. & Bierut, L. J., Oct 1 2014, In : Alcoholism: Clinical and Experimental Research. 38, 10, p. 2541-2549 9 p.

Research output: Contribution to journalArticle

Gene-Environment Interaction
Alcohol Dehydrogenase
Drinking
Genes
Alcohols
103 Citations (Scopus)

APOE and BCHE as modulators of cerebral amyloid deposition: A florbetapir PET genome-wide association study

Ramanan, V. K., Risacher, S. L., Nho, K., Kim, S., Swaminathan, S., Shen, L., Foroud, T., Hakonarson, H., Huentelman, M. J., Aisen, P. S., Petersen, R. C., Green, R. C., Jack, C. R., Koeppe, R. A., Jagust, W. J., Weiner, M. W. & Saykin, A., Mar 2014, In : Molecular Psychiatry. 19, 3, p. 351-357 7 p.

Research output: Contribution to journalArticle

Butyrylcholinesterase
Genome-Wide Association Study
Apolipoproteins E
Amyloid
Positron-Emission Tomography
24 Citations (Scopus)

APOE ε4 and the risk for Alzheimer disease and cognitive decline in African Americans and Yoruba

Hendrie, H., Murrell, J., Baiyewu, O., Lane, K. A., Purnell, C., Ogunniyi, A., Unverzagt, F., Hall, K., Callahan, C., Saykin, A., Gureje, O., Hake, A., Foroud, T. & Gao, S., 2014, In : International Psychogeriatrics. 26, 6, p. 977-985 9 p.

Research output: Contribution to journalArticle

African Americans
Alzheimer Disease
Alleles
Longitudinal Studies
Independent Living
25 Citations (Scopus)

Association of plasma and cortical amyloid beta is modulated by APOE ε4 status

Swaminathan, S., Risacher, S. L., Yoder, K., West, J. D., Shen, L., Kim, S., Inlow, M., Foroud, T., Jagust, W. J., Koeppe, R. A., Mathis, C. A., Shaw, L. M., Trojanowski, J. Q., Soares, H., Aisen, P. S., Petersen, R. C., Weiner, M. W. & Saykin, A., Jan 2014, In : Alzheimer's and Dementia. 10, 1

Research output: Contribution to journalArticle

Apolipoprotein E4
Amyloid
Apolipoproteins E
Alzheimer Disease
Alleles
2 Citations (Scopus)

Complex Genetics of Alcoholism

Edenberg, H. & Foroud, T., Feb 2014, Neurobiology of Alcohol Dependence. Elsevier Inc., p. 539-550 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Alcoholism
Alcohols
Genes
Phenotype
Genome-Wide Association Study
25 Citations (Scopus)

DSM-5 cannabis use disorder: A phenotypic and genomic perspective

Agrawal, A., Lynskey, M. T., Bucholz, K. K., Kapoor, M., Almasy, L., Dick, D. M., Edenberg, H., Foroud, T., Goate, A., Hancock, D. B., Hartz, S., Johnson, E. O., Hesselbrock, V., Kramer, J. R., Kuperman, S., Nurnberger, J., Schuckit, M. & Bierut, L. J., Jan 1 2014, In : Drug and Alcohol Dependence. 134, 1, p. 362-369 8 p.

Research output: Contribution to journalArticle

Cannabis
Polymorphism
Single Nucleotide Polymorphism
Genes
Nucleotides
83 Citations (Scopus)

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: A genome-wide association study

Alzheimer Disease Genetics Consortium, Nov 1 2014, In : JAMA Neurology. 71, 11, p. 1394-1404 11 p.

Research output: Contribution to journalArticle

Genetic Loci
Genome-Wide Association Study
Age of Onset
Alzheimer Disease
Genetic Databases
5 Citations (Scopus)

Ethanol treatment of lymphoblastoid cell lines from alcoholics and non-alcoholics causes many subtle changes in gene expression

McClintick, J., Brooks, A. I., Deng, L., Liang, L., Wang, J. C., Kapoor, M., Xuei, X., Foroud, T., Tischfield, J. A. & Edenberg, H., Sep 1 2014, In : Alcohol. 48, 6, p. 603-610 8 p.

Research output: Contribution to journalArticle

Alcoholics
alcoholism
Gene expression
Ethanol
Cells
16 Citations (Scopus)

Family-Based Association Analysis of Alcohol Dependence Criteria and Severity

Wetherill, L., Kapoor, M., Agrawal, A., Bucholz, K., Koller, D., Bertelsen, S. E., Le, N., Wang, J. C., Almasy, L., Hesselbrock, V., Kramer, J., Nurnberger, J., Schuckit, M., Tischfield, J. A., Xuei, X., Porjesz, B., Edenberg, H., Goate, A. M. & Foroud, T., Feb 2014, In : Alcoholism: Clinical and Experimental Research. 38, 2, p. 354-366 13 p.

Research output: Contribution to journalArticle

Alcoholism
Alcohols
Diagnostic and Statistical Manual of Mental Disorders
Genes
Single Nucleotide Polymorphism
76 Citations (Scopus)

Genetic analysis of quantitative phenotypes in AD and MCI: Imaging, cognition and biomarkers

Shen, L., Thompson, P. M., Potkin, S. G., Bertram, L., Farrer, L. A., Foroud, T., Green, R. C., Hu, X., Huentelman, M. J., Kim, S., Kauwe, J. S. K., Li, Q., Liu, E., Macciardi, F., Moore, J. H., Munsie, L., Nho, K., Ramanan, V. K., Risacher, S. L., Stone, D. J. & 4 others, Swaminathan, S., Toga, A. W., Weiner, M. W. & Saykin, A., 2014, In : Brain Imaging and Behavior. 8, 2, p. 183-207 25 p.

Research output: Contribution to journalArticle

Cognition
Alzheimer Disease
Neuroimaging
Biomarkers
Phenotype

Genetic inheritance and population genetics

Foroud, T. & Koller, D. L., Mar 1 2014, Molecular Genetic Pathology: Second Edition. Springer New York, p. 111-127 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Population Genetics
Molecular Pathology
Documentation
21 Citations (Scopus)

Genetics of alcoholism

Edenberg, H. & Foroud, T., 2014, In : Handbook of Clinical Neurology. 125, p. 561-571 11 p.

Research output: Contribution to journalArticle

Alcoholism
Alcohols
Genes
Aldehyde Dehydrogenase
Genetic Linkage
23 Citations (Scopus)

Genetic variant predicts bevacizumab-induced hypertension in ECOG-5103 and ECOG-2100

Schneider, B., Li, L., Shen, F., Miller, K., Radovich, M., O'Neill, A., Gray, R. J., Lane, D., Flockhart, D. A., Jiang, G., Wang, Z., Lai, D., Koller, D., Pratt, J. H., Dang, C. T., Northfelt, D., Perez, E. A., Shenkier, T., Cobleigh, M., Smith, M. L. & 7 others, Railey, E., Partridge, A., Gralow, J., Sparano, J., Davidson, N. E., Foroud, T. & Sledge, G. W., Sep 9 2014, In : British Journal of Cancer. 111, 6, p. 1241-1248 8 p.

Research output: Contribution to journalArticle

Hypertension
Blood Pressure
Genome-Wide Association Study
Single Nucleotide Polymorphism
Genome
58 Citations (Scopus)

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

Escott-Price, V., Bellenguez, C., Wang, L. S., Choi, S. H., Harold, D., Jones, L., Holmans, P., Gerrish, A., Vedernikov, A., Richards, A., DeStefano, A. L., Lambert, J. C., Ibrahim-Verbaas, C. A., Naj, A. C., Sims, R., Jun, G., Bis, J. C., Beecham, G. W., Grenier-Boley, B., Russo, G. & 167 others, Thornton-Wells, T. A., Denning, N., Smith, A. V., Chouraki, V., Thomas, C., Arfan Ikram, M., Zelenika, D., Vardarajan, B. N., Kamatani, Y., Lin, C. F., Schmidt, H., Kunkle, B., Dunstan, M. L., Vronskaya, M., Johnson, A. D., Ruiz, A., Bihoreau, M. T., Reitz, C., Pasquier, F., Hollingworth, P., Hanon, O., Fitzpatrick, A. L., Buxbaum, J. D., Campion, D., Crane, P. K., Becker, C. B. T., Gudnason, V., Cruchaga, C., Craig, D., Amin, N., Berr, C., Lopez, O. L., De Jager, P. L., Deramecourt, V., Johnston, J. A., Evans, D., Lovestone, S., Letenneur, L., Hernández, I., Rubinsztein, D. C., Eiriksdottir, G., Sleegers, K., Goate, A. M., Fiévet, N., Huentelman, M. J., Gill, M., Brown, K., Kamboh, M. I., Keller, L., Barberger-Gateau, P., McGuinness, B., Larson, E. B., Myers, A. J., Dufouil, C., Todd, S., Wallon, D., Love, S., Rogaeva, E., Gallacher, J., St George-Hyslop, P., Clarimon, J., Lleo, A., Bayer, A., Tsuang, D. W., Yu, L., Tsolaki, M., Bossù, P., Spalletta, G., Proitsi, P., Collinge, J., Sorbi, S., Sanchez Garcia, F., Fox, N. C., Hardy, J., Naranjo, M. C. D., Bosco, P., Clarke, R., Brayne, C., Galimberti, D., Scarpini, E., Bonuccelli, U., Mancuso, M., Siciliano, G., Moebus, S., Mecocci, P., Del Zompo, M., Maier, W., Hampel, H., Pilotto, A., Frank-García, A., Panza, F., Solfrizzi, V., Caffarra, P., Nacmias, B., Perry, W., Mayhaus, M., Lannfelt, L., Hakonarson, H., Pichler, S., Carrasquillo, M. M., Ingelsson, M., Beekly, D., Alvarez, V., Zou, F., Valladares, O., Younkin, S. G., Coto, E., Hamilton-Nelson, K. L., Gu, W., Razquin, C., Pastor, P., Mateo, I., Owen, M. J., Faber, K. M., Jonsson, P. V., Combarros, O., O'Donovan, M. C., Cantwell, L. B., Soininen, H., Blacker, D., Mead, S., Mosley, T. H., Bennett, D. A., Harris, T. B., Fratiglioni, L., Holmes, C., De Bruijn, R. F. A. G., Passmore, P., Montine, T. J., Bettens, K., Rotter, J. I., Brice, A., Morgan, K., Foroud, T., Kukull, W. A., Hannequin, D., Powell, J. F., Nalls, M. A., Ritchie, K., Lunetta, K. L., Kauwe, J. S. K., Boerwinkle, E., Riemenschneider, M., Boada, M., Hiltunen, M., Martin, E. R., Schmidt, R., Rujescu, D., Dartigues, J. F., Mayeux, R., Tzourio, C., Hofman, A., Nöthen, M. M., Graff, C., Psaty, B. M., Haines, J. L., Lathrop, M., Pericak-Vance, M. A., Launer, L. J., Van Broeckhoven, C., Farrer, L. A., Van Duijn, C. M., Ramirez, A., Seshadri, S., Schellenberg, G. D., Amouyel, P. & Williams, J., Jun 12 2014, In : PLoS One. 9, 6, e94661.

Research output: Contribution to journalArticle

Alzheimer disease
Alzheimer Disease
Genes
genes
loci
9 Citations (Scopus)

Genomes and phenomes of a population of outbred rats and its progenitors

The Rat Genome Sequencing and Mapping Consortium, Jun 10 2014, In : Scientific data. 1, 140011.

Research output: Contribution to journalArticle

Rats
Genome
Genes
Osteoporosis
bone disease
29 Citations (Scopus)

Genome-wide association study of intracranial aneurysm identifies a new association on chromosome 7

Foroud, T., Lai, D., Koller, D., Van't Hof, F., Kurki, M. I., Anderson, C. S., Brown, R. D., Connolly, E. S., Eriksson, J. G., Flaherty, M., Fornage, M., Von Und Zu Fraunberg, M., Gaál, E. I., Laakso, A., Hernesniemi, J., Huston, J., Jääskeläinen, J. E., Kiemeney, L. A., Kivisaari, R., Kleindorfer, D. & 20 others, Ko, N., Lehto, H., Mackey, J., Meissner, I., Moomaw, C. J., Mosley, T. H., Moskala, M., Niemelä, M., Palotie, A., Pera, J., Rinkel, G., Ripke, S., Rouleau, G., Ruigrok, Y., Sauerbeck, L., Słowik, A., Vermeulen, S. H., Woo, D., Worrall, B. B. & Broderick, J., 2014, In : Stroke. 45, 11, p. 3194-3199 6 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 7
Genome-Wide Association Study
Intracranial Aneurysm
Stroke
Meta-Analysis
41 Citations (Scopus)

Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty

The ReproGen Consortium, The Early Growth Genetics (EGG) Consortium, The Early Growth Genetics (EGG) Consortium, The ReproGen Consortium & The GIANT Consortium, Jan 1 2014, In : Human molecular genetics. 23, 16, p. 4452-4464 13 p.

Research output: Contribution to journalArticle

Open Access
Sexual Maturation
Menarche
Genome-Wide Association Study
Puberty
Sexual Development
13 Citations (Scopus)

Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families

Kapoor, M., Wang, J. C., Wetherill, L., Le, N., Bertelsen, S., Hinrichs, A. L., Budde, J., Agrawal, A., Almasy, L., Bucholz, K., Dick, D. M., Harari, O., Xuei, X., Hesselbrock, V., Kramer, J., Nurnberger, J., Rice, J., Schuckit, M., Tischfield, J., Porjesz, B. & 4 others, Edenberg, H., Bierut, L., Foroud, T. & Goate, A., Sep 1 2014, In : Drug and Alcohol Dependence. 142, p. 56-62 7 p.

Research output: Contribution to journalArticle

Survival Analysis
Age of Onset
Alcoholism
Genes
Alcohols