Tatiana Foroud

  • 42200 Citations
  • 101 h-Index
1976 …2021
If you made any changes in Pure, your changes will be visible here soon.

Publications 1988 2020

Filter
Article
2013
14 Citations (Scopus)

Cis-regulatory variants affect CHRNA5 mRNA expression in populations of African and European ancestry

Wang, J. C., Spiegel, N., Bertelsen, S., Le, N., McKenna, N., Budde, J. P., Harari, O., Kapoor, M., Brooks, A., Hancock, D., Tischfield, J., Foroud, T., Bierut, L. J., Steinbach, J. H., Edenberg, H., Traynor, B. J. & Goate, A. M., Nov 26 2013, In : PLoS One. 8, 11, e80204.

Research output: Contribution to journalArticle

ancestry
Genes
Multigene Family
Messenger RNA
Alleles
94 Citations (Scopus)

Combined sequence-based and genetic mapping analysis of complex traits in outbred rats

Baud, A., Hermsen, R., Guryev, V., Stridh, P., Graham, D., McBride, M. W., Foroud, T., Calderari, S., Diez, M., Ockinger, J., Beyeen, A. D., Gillett, A., Abdelmagid, N., Guerreiro-Cacais, A. O., Jagodic, M., Tuncel, J., Norin, U., Beattie, E., Huynh, N., Miller, W. H. & 50 others, Koller, D. L., Alam, I., Falak, S., Osborne-Pellegrin, M., Martinez-Membrives, E., Canete, T., Blazquez, G., Vicens-Costa, E., Mont-Cardona, C., Diaz-Moran, S., Tobena, A., Hummel, O., Zelenika, D., Saar, K., Patone, G., Bauerfeind, A., Bihoreau, M. T., Heinig, M., Lee, Y. A., Rintisch, C., Schulz, H., Wheeler, D. A., Worley, K. C., Muzny, D. M., Gibbs, R. A., Lathrop, M., Lansu, N., Toonen, P., Ruzius, F. P., De Bruijn, E., Hauser, H., Adams, D. J., Keane, T., Atanur, S. S., Aitman, T. J., Flicek, P., Malinauskas, T., Jones, E. Y., Ekman, D., Lopez-Aumatell, R., Dominiczak, A. F., Johannesson, M., Holmdahl, R., Olsson, T., Gauguier, D., Hubner, N., Fernandez-Teruel, A., Cuppen, E., Mott, R. & Flint, J., Jul 2013, In : Nature Genetics. 45, 7, p. 767-775 9 p.

Research output: Contribution to journalArticle

Quantitative Trait Loci
Phenotype
Genes
Multiple Sclerosis
Heart Diseases
17 Citations (Scopus)

Common biological networks underlie genetic risk for alcoholism in African- and European-American populations

Kos, M. Z., Yan, J., Dick, D. M., Agrawal, A., Bucholz, K. K., Rice, J. P., Johnson, E. O., Schuckit, M., Kuperman, S., Kramer, J., Goate, A. M., Tischfield, J. A., Foroud, T., Nurnberger, J., Hesselbrock, V., Porjesz, B., Bierut, L. J., Edenberg, H. & Almasy, L., Jul 2013, In : Genes, Brain and Behavior. 12, 5, p. 532-542 11 p.

Research output: Contribution to journalArticle

African Americans
Alcoholism
Genome-Wide Association Study
Population
Genes
26 Citations (Scopus)

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking

Stephens, S. H., Hartz, S. M., Hoft, N. R., Saccone, N. L., Corley, R. C., Hewitt, J. K., Hopfer, C. J., Breslau, N., Coon, H., Chen, X., Ducci, F., Dueker, N., Franceschini, N., Frank, J., Han, Y., Hansel, N. N., Jiang, C., Korhonen, T., Lind, P. A., Liu, J. & 106 others, Lyytikäinen, L. P., Michel, M., Shaffer, J. R., Short, S. E., Sun, J., Teumer, A., Thompson, J. R., Vogelzangs, N., Vink, J. M., Wenzlaff, A., Wheeler, W., Yang, B. Z., Aggen, S. H., Balmforth, A. J., Baumeister, S. E., Beaty, T. H., Benjamin, D. J., Bergen, A. W., Broms, U., Cesarini, D., Chatterjee, N., Chen, J., Cheng, Y. C., Cichon, S., Couper, D., Cucca, F., Dick, D., Foroud, T., Furberg, H., Giegling, I., Gillespie, N. A., Gu, F., Hall, A. S., Hällfors, J., Han, S., Hartmann, A. M., Heikkilä, K., Hickie, I. B., Hottenga, J. J., Jousilahti, P., Kaakinen, M., Kähönen, M., Koellinger, P. D., Kittner, S., Konte, B., Landi, M. T., Laatikainen, T., Leppert, M., Levy, S. M., Mathias, R. A., Mcneil, D. W., Medland, S. E., Montgomery, G. W., Murray, T., Nauck, M., North, K. E., Paré, P. D., Pergadia, M., Ruczinski, I., Salomaa, V., Viikari, J., Willemsen, G., Barnes, K. C., Boerwinkle, E., Boomsma, D. I., Caporaso, N., Edenberg, H., Francks, C., Gelernter, J., Grabe, H. J., Hops, H., Jarvelin, M. R., Johannesson, M., Kendler, K. S., Lehtimäki, T., Magnusson, P. K. E., Marazita, M. L., Marchini, J., Mitchell, B. D., Nöthen, M. M., Penninx, B. W., Raitakari, O., Rietschel, M., Rujescu, D., Samani, N. J., Schwartz, A. G., Shete, S., Spitz, M., Swan, G. E., Völzke, H., Veijola, J., Wei, Q., Amos, C., Cannon, D. S., Grucza, R., Hatsukami, D., Heath, A., Johnson, E. O., Kaprio, J., Madden, P., Martin, N. G., Stevens, V. L., Weiss, R. B., Kraft, P., Bierut, L. J. & Ehringer, M. A., Dec 2013, In : Genetic Epidemiology. 37, 8, p. 846-859 14 p.

Research output: Contribution to journalArticle

Multigene Family
Smoking
Tobacco Use Disorder
Phenotype
Tobacco
99 Citations (Scopus)

Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants

Gamazon, E. R., Badner, J. A., Cheng, L., Zhang, C., Zhang, D., Cox, N. J., Gershon, E. S., Kelsoe, J. R., Greenwood, T. A., Nievergelt, C. M., Chen, C., McKinney, R., Shilling, P. D., Schork, N. J., Smith, E. N., Bloss, C. S., Nurnberger, J., Edenberg, H., Foroud, T., Koller, D. L. & 20 others, Scheftner, W. A., Coryell, W., Rice, J., Lawson, W. B., Nwulia, E. A., Hipolito, M., Byerley, W., McMahon, F. J., Schulze, T. G., Berrettini, W. H., Potash, J. B., Zandi, P. P., Mahon, P. B., McInnis, M. G., Zöllner, S., Zhang, P., Craig, D. W., Szelinger, S., Barrett, T. B. & Liu, C., Mar 2013, In : Molecular Psychiatry. 18, 3, p. 340-346 7 p.

Research output: Contribution to journalArticle

Quantitative Trait Loci
Regulator Genes
Bipolar Disorder
Methylation
Single Nucleotide Polymorphism
57 Citations (Scopus)

Facial dysmorphism across the fetal alcohol spectrum

Suttie, M., Foroud, T., Wetherill, L., Jacobson, J. L., Molteno, C. D., Meintjes, E. M., Hoyme, H. E., Khaole, N., Robinson, L. K., Riley, E. P., Jacobson, S. W. & Hammond, P., Mar 2013, In : Pediatrics. 131, 3

Research output: Contribution to journalArticle

Alcohols
Fetal Alcohol Spectrum Disorders
Alcohol
Eyelids
Lip
13 Citations (Scopus)

Familial intracranial aneurysms: Is anatomic vulnerability heritable?

Mackey, J., Brown, R. D., Moomaw, C. J., Hornung, R., Sauerbeck, L., Woo, D., Foroud, T., Gandhi, D., Kleindorfer, D., Flaherty, M. L., Meissner, I., Anderson, C., Rouleau, G., Connolly, E. S., Deka, R., Koller, D. L., Abruzzo, T., Huston, J. & Broderick, J. P., Jan 2013, In : Stroke. 44, 1, p. 38-42 5 p.

Research output: Contribution to journalArticle

Intracranial Aneurysm
Odds Ratio
Middle Cerebral Artery
Internal Carotid Artery
Rupture
32 Citations (Scopus)
MicroRNAs
Alzheimer Disease
Neurodegenerative Diseases
Neoplasms
Apoptosis
16 Citations (Scopus)

Genetic and neurophysiological correlates of the age of onset of alcohol use disorders in adolescents and young adults

Chorlian, D. B., Rangaswamy, M., Manz, N., Wang, J. C., Dick, D., Almasy, L., Bauer, L., Bucholz, K., Foroud, T., Hesselbrock, V., Kang, S. J., Kramer, J., Kuperman, S., Nurnberger, J., Rice, J., Schuckit, M., Tischfield, J., Edenberg, H., Goate, A., Bierut, L. & 1 others, Porjesz, B., 2013, In : Behavior Genetics. 43, 5, p. 386-401 16 p.

Research output: Contribution to journalArticle

young adults
Age of Onset
Alcoholism
Young Adult
alcohol
33 Citations (Scopus)

Genetic influences on craving for alcohol

Agrawal, A., Wetherill, L., Bucholz, K. K., Kramer, J., Kuperman, S., Lynskey, M. T., Nurnberger, J., Schuckit, M., Tischfield, J. A., Edenberg, H., Foroud, T. & Bierut, L. J., Feb 2013, In : Addictive Behaviors. 38, 2, p. 1501-1508 8 p.

Research output: Contribution to journalArticle

Alcohols
Alcoholism
Genes
Polymorphism
Nucleotides
1120 Citations (Scopus)

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Lee, S. H., Ripke, S., Neale, B. M., Faraone, S. V., Purcell, S. M., Perlis, R. H., Mowry, B. J., Thapar, A., Goddard, M. E., Witte, J. S., Absher, D., Agartz, I., Akil, H., Amin, F., Andreassen, O. A., Anjorin, A., Anney, R., Anttila, V., Arking, D. E., Asherson, P. & 350 others, Azevedo, M. H., Backlund, L., Badner, J. A., Bailey, A. J., Banaschewski, T., Barchas, J. D., Barnes, M. R., Barrett, T. B., Bass, N., Battaglia, A., Bauer, M., Bayés, M., Bellivier, F., Bergen, S. E., Berrettini, W., Betancur, C., Bettecken, T., Biederman, J., Binder, E. B., Black, D. W., Blackwood, D. H. R., Bloss, C. S., Boehnke, M., Boomsma, D. I., Breen, G., Breuer, R., Bruggeman, R., Cormican, P., Buccola, N. G., Buitelaar, J. K., Bunney, W. E., Buxbaum, J. D., Byerley, W. F., Byrne, E. M., Caesar, S., Cahn, W., Cantor, R. M., Casas, M., Chakravarti, A., Chambert, K., Choudhury, K., Cichon, S., Cloninger, C. R., Collier, D. A., Cook, E. H., Coon, H., Cormand, B., Corvin, A., Coryell, W. H., Craig, D. W., Craig, I. W., Crosbie, J., Cuccaro, M. L., Curtis, D., Czamara, D., Datta, S., Dawson, G., Day, R., De Geus, E. J., Degenhardt, F., Djurovic, S., Donohoe, G. J., Doyle, A. E., Duan, J., Dudbridge, F., Duketis, E., Ebstein, R. P., Edenberg, H., Elia, J., Ennis, S., Etain, B., Fanous, A., Farmer, A. E., Ferrier, I. N., Flickinger, M., Fombonne, E., Foroud, T., Frank, J., Franke, B., Fraser, C., Freedman, R., Freimer, N. B., Freitag, C. M., Friedl, M., Frisén, L., Gallagher, L., Gejman, P. V., Georgieva, L., Gershon, E. S., Geschwind, D. H., Giegling, I., Gill, M., Gordon, S. D., Gordon-Smith, K., Green, E. K., Greenwood, T. A., Grice, D. E., Gross, M., Grozeva, D., Guan, W., Gurling, H., De Haan, L., Haines, J. L., Hakonarson, H., Hallmayer, J., Hamilton, S. P., Hamshere, M. L., Hansen, T. F., Hartmann, A. M., Hautzinger, M., Heath, A. C., Henders, A. K., Herms, S., Hickie, I. B., Hipolito, M., Hoefels, S., Holmans, P. A., Holsboer, F., Hoogendijk, W. J., Hottenga, J. J., Hultman, C. M., Hus, V., Ingason, A., Ising, M., Jamain, S., Jones, E. G., Jones, I., Jones, L., Tzeng, J. Y., Kähler, A. K., Kahn, R. S., Kandaswamy, R., Keller, M. C., Kennedy, J. L., Kenny, E., Kent, L., Kim, Y., Kirov, G. K., Klauck, S. M., Klei, L., Knowles, J. A., Kohli, M. A., Koller, D. L., Konte, B., Korszun, A., Krabbendam, L., Krasucki, R., Kuntsi, J., Kwan, P., Landén, M., Långström, N., Lathrop, M., Lawrence, J., Lawson, W. B., Leboyer, M., Ledbetter, D. H., Lee, P. H., Lencz, T., Lesch, K. P., Levinson, D. F., Lewis, C. M., Li, J., Lichtenstein, P., Lieberman, J. A., Lin, D. Y., Linszen, D. H., Liu, C., Lohoff, F. W., Loo, S. K., Lord, C., Lowe, J. K., Lucae, S., Macintyre, D. J., Madden, P. A. F., Maestrini, E., Magnusson, P. K. E., Mahon, P. B., Maier, W., Malhotra, A. K., Mane, S. M., Martin, C. L., Martin, N. G., Mattheisen, M., Matthews, K., Mattingsdal, M., Mccarroll, S. A., Mcghee, K. A., Mcgough, J. J., Mcgrath, P. J., Mcguffin, P., Mcinnis, M. G., Mcintosh, A., Mckinney, R., Mclean, A. W., Mcmahon, F. J., Mcmahon, W. M., Mcquillin, A., Medeiros, H., Medland, S. E., Meier, S., Melle, I., Meng, F., Meyer, J., Middeldorp, C. M., Middleton, L., Milanova, V., Miranda, A., Monaco, A. P., Montgomery, G. W., Moran, J. L., Moreno-De-Luca, D., Morken, G., Morris, D. W., Morrow, E. M., Moskvina, V., Muglia, P., Mühleisen, T. W., Muir, W. J., Müller-Myhsok, B., Murtha, M., Myers, R. M., Myin-Germeys, I., Neale, M. C., Nelson, S. F., Nievergelt, C. M., Nikolov, I., Nimgaonkar, V., Nolen, W. A., Nöthen, M. M., Nurnberger, J., Nwulia, E. A., Nyholt, D. R., O'dushlaine, C., Oades, R. D., Olincy, A., Oliveira, G., Olsen, L., Ophoff, R. A., Osby, U., Owen, M. J., Palotie, A., Parr, J. R., Paterson, A. D., Pato, C. N., Pato, M. T., Penninx, B. W., Pergadia, M. L., Pericak-Vance, M. A., Pickard, B. S., Pimm, J., Piven, J., Posthuma, D., Potash, J. B., Poustka, F., Propping, P., Puri, V., Quested, D. J., Quinn, E. M., Ramos-Quiroga, J. A., Rasmussen, H. B., Raychaudhuri, S., Rehnström, K., Reif, A., Ribasés, M., Rice, J. P., Rietschel, M., Roeder, K., Roeyers, H., Rossin, L., Rothenberger, A., Rouleau, G., Ruderfer, D., Rujescu, D., Sanders, A. R., Sanders, S. J., Santangelo, S. L., Sergeant, J. A., Schachar, R., Schalling, M., Schatzberg, A. F., Scheftner, W. A., Schellenberg, G. D., Scherer, S. W., Schork, N. J., Schulze, T. G., Schumacher, J., Schwarz, M., Scolnick, E., Scott, L. J., Shi, J., Shilling, P. D., Shyn, S. I., Silverman, J. M., Slager, S. L., Smalley, S. L., Smit, J. H., Smith, E. N., Sonuga-Barke, E. J. S., St. Clair, D., State, M., Steffens, M., Steinhausen, H. C., Strauss, J. S., Strohmaier, J., Stroup, T. S., Sutcliffe, J. S., Szatmari, P., Szelinger, S., Thirumalai, S., Thompson, R. C., Todorov, A. A., Tozzi, F., Treutlein, J., Uhr, M., Van Den Oord, E. J. C. G., Van Grootheest, G., Van Os, J., Vicente, A. M., Vieland, V. J., Vincent, J. B., Visscher, P. M., Walsh, C. A., Wassink, T. H., Watson, S. J., Weissman, M. M., Werge, T., Wienker, T. F., Wijsman, E. M., Willemsen, G., Williams, N., Willsey, A. J., Witt, S. H., Xu, W., Young, A. H., Yu, T. W., Zammit, S., Zandi, P. P., Zhang, P., Zitman, F. G., Zöllner, S., Devlin, B., Kelsoe, J. R., Sklar, P., Daly, M. J., O'donovan, M. C., Craddock, N., Sullivan, P. F., Smoller, J. W., Kendler, K. S. & Wray, N. R., Sep 2013, In : Nature Genetics. 45, 9, p. 984-994 11 p.

Research output: Contribution to journalArticle

Major Depressive Disorder
Single Nucleotide Polymorphism
Psychiatry
Schizophrenia
Bipolar Disorder
61 Citations (Scopus)

Genetics and alcoholism

Edenberg, H. & Foroud, T., Aug 2013, In : Nature Reviews Gastroenterology and Hepatology. 10, 8, p. 487-494 8 p.

Research output: Contribution to journalArticle

Alcoholism
Genes
Alcohols
Inborn Genetic Diseases
Social Problems
14 Citations (Scopus)

Genome-Wide Association Study of Irritable vs. Elated Mania Suggests Genetic Differences between Clinical Subtypes of Bipolar Disorder

Greenwood, T. A., Kelsoe, J. R., Kelsoe, J. R., Greenwood, T. A., Nievergelt, C. M., McKinney, R., Shilling, P. D., Smith, E. N., Schork, N. J., Bloss, C. S., Nurnberger, J. I., Edenberg, H. J., Foroud, T., Koller, D. L., Gershon, E. S., Liu, C., Badner, J. A., Scheftner, W. A., Lawson, W. B., Nwulia, E. A. & 16 others, Hipolito, M., Coryell, W., Potash, J. B., Rice, J., Byerley, W., McMahon, F. J., Nurnberger, J., Edenberg, H., Foroud, T., Mahon, P. B., McInnis, M. G., Zöllner, S., Zhang, P., Craig, D. W., Szelinger, S. & Barrett, T. B., Jan 17 2013, In : PLoS One. 8, 1, e53804.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Bipolar Disorder
Genes
Chromosomes
Genome
6 Citations (Scopus)

Identification of functional variants from whole-exome sequencing, combined with neuroimaging genetics

Nho, K., Corneveaux, J. J., Kim, S., Lin, H., Risacher, S. L., Shen, L., Swaminathan, S., Ramanan, V. K., Liu, Y., Foroud, T., Inlow, M. H., Siniard, A. L., Reiman, R. A., Aisen, P. S., Petersen, R. C., Green, R. C., Jack, C. R., Weiner, M. W., Baldwin, C. T., Lunetta, K. & 14 others, Farrer, L. A., Furney, S. J., Lovestone, S., Simmons, A., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., McDonald, B., Farlow, M., Ghetti, B., Huentelman, M. J. & Saykin, A., Jul 2013, In : Molecular Psychiatry. 18, 7, p. 739 1 p.

Research output: Contribution to journalArticle

Exome
Genome-Wide Association Study
Neuroimaging
Atrophy
Hippocampus
35 Citations (Scopus)

Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP)

Reitz, C., Tosto, G., Vardarajan, B., Rogaeva, E., Ghani, M., Rogers, R. S., Conrad, C., Haines, J. L., Pericak-Vance, M. A., Fallin, M. D., Foroud, T., Farrer, L. A., Schellenberg, G. D., George-Hyslop, P. S. & Mayeux, R., 2013, In : Translational Psychiatry. 3, e256.

Research output: Contribution to journalArticle

Amyloid beta-Protein Precursor
Protein Transport
Alzheimer Disease
Single Nucleotide Polymorphism
Genes
42 Citations (Scopus)

Influence of Genetic Variation on Plasma Protein Levels in Older Adults Using a Multi-Analyte Panel

Kim, S., Swaminathan, S., Inlow, M., Risacher, S. L., Nho, K., Shen, L., Foroud, T., Petersen, R. C., Aisen, P. S., Soares, H., Toledo, J. B., Shaw, L. M., Trojanowski, J. Q., Weiner, M. W., McDonald, B., Farlow, M., Ghetti, B. & Saykin, A., Jul 23 2013, In : PLoS One. 8, 7, e70269.

Research output: Contribution to journalArticle

blood proteins
Blood Proteins
Polymorphism
Single Nucleotide Polymorphism
genetic variation
12 Citations (Scopus)

Measurement invariance of DSM-IV alcohol, marijuana and cocaine dependence between community-sampled and clinically overselected studies

Derringer, J., Krueger, R. F., Dick, D. M., Agrawal, A., Bucholz, K. K., Foroud, T., Grucza, R. A., Hesselbrock, M. N., Hesselbrock, V., Kramer, J., Nurnberger, J., Schuckit, M., Bierut, L. J., Iacono, W. G. & Mcgue, M., Oct 2013, In : Addiction. 108, 10, p. 1767-1776 10 p.

Research output: Contribution to journalArticle

Marijuana Abuse
Cocaine-Related Disorders
Diagnostic and Statistical Manual of Mental Disorders
Alcoholism
Substance-Related Disorders
1572 Citations (Scopus)

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

European Alzheimer's Disease Initiative (EADI), Genetic and Environmental Risk in Alzheimer's Disease (GEGERAD), Alzheimer's Disease Genetic Consortium (ADGCDGCDGC) & Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGEGE), Dec 1 2013, In : Nature Genetics. 45, 12, p. 1452-1458 7 p.

Research output: Contribution to journalArticle

Meta-Analysis
Alzheimer Disease
Genome-Wide Association Study
Single Nucleotide Polymorphism
Inborn Genetic Diseases
56 Citations (Scopus)

Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women

Koller, D. L., Zheng, H. F., Karasik, D., Yerges-Armstrong, L., Liu, C. T., McGuigan, F., Kemp, J. P., Giroux, S., Lai, D., Edenberg, H., Peacock, M., Czerwinski, S. A., Choh, A. C., McMahon, G., St Pourcain, B., Timpson, N. J., Lawlor, D. A., Evans, D. M., Towne, B., Blangero, J. & 14 others, Carless, M. A., Kammerer, C., Goltzman, D., Kovacs, C. S., Prior, J. C., Spector, T. D., Rousseau, F., Tobias, J. H., Akesson, K., Econs, M., Mitchell, B. D., Richards, J. B., Kiel, D. P. & Foroud, T., Mar 2013, In : Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 28, 3, p. 547-558 12 p.

Research output: Contribution to journalArticle

Bone Density
Single Nucleotide Polymorphism
Meta-Analysis
Genome
Spine
160 Citations (Scopus)

Mutations in COQ2 in familial and sporadic multiple-system atrophy the multiple-system atrophy research collaboration

Mitsui, J., Matsukawa, T., Ishiura, H., Fukuda, Y., Ichikawa, Y., Date, H., Ahsan, B., Nakahara, Y., Momose, Y., Takahashi, Y., Iwata, A., Goto, J., Yamamoto, Y., Komata, M., Shirahige, K., Hara, K., Kakita, A., Yamada, M., Takahashi, H., Onodera, O. & 54 others, Nishizawa, M., Takashima, H., Kuwano, R., Watanabe, H., Ito, M., Sobue, G., Soma, H., Yabe, I., Sasaki, H., Aoki, M., Ishikawa, K., Mizusawa, H., Kanai, K., Hattori, T., Kuwabara, S., Arai, K., Koyano, S., Kuroiwa, Y., Hasegawa, K., Yuasa, T., Yasui, K., Nakashima, K., Ito, H., Izumi, Y., Kaji, R., Kato, T., Kusunoki, S., Osaki, Y., Horiuchi, M., Kondo, T., Murayama, S., Hattori, N., Yamamoto, M., Murata, M., Satake, W., Toda, T., Dürr, A., Brice, A., Filla, A., Klockgether, T., Wallner, U., Nicholson, G., Gilman, S., Shults, C. W., Tanner, C. M., Kukull, W. A., Lee, V. M. Y., Masliah, E., Low, P. A., Sandroni, P., Trojanowski, J. Q., Ozelius, L., Foroud, T. & Tsuji, S., 2013, In : New England Journal of Medicine. 369, 3, p. 233-244 12 p.

Research output: Contribution to journalArticle

Multiple System Atrophy
coenzyme Q10
Mutation
Research
Cerebellar Ataxia
51 Citations (Scopus)

Pdgfra protects against ethanol-induced craniofacial defects in a zebrafish model of FASD

Mccarthy, N., Wetherill, L., Lovely, C. B., Swartz, M. E., Foroud, T. & Eberhart, J. K., Aug 1 2013, In : Development (Cambridge). 140, 15, p. 3254-3265 12 p.

Research output: Contribution to journalArticle

Fetal Alcohol Spectrum Disorders
Platelet-Derived Growth Factor alpha Receptor
Zebrafish
Ethanol
Neural Crest
3 Citations (Scopus)
Chromosomes, Human, Pair 4
Quantitative Trait Loci
Neuropeptide Y
Corticotropin-Releasing Hormone
body weight
64 Citations (Scopus)

Serum Iron Levels and the Risk of Parkinson Disease: A Mendelian Randomization Study

Pichler, I., Del Greco, M. F., Gögele, M., Lill, C. M., Bertram, L., Do, C. B., Eriksson, N., Foroud, T., Myers, R. H., Nalls, M., Keller, M. F., Benyamin, B., Whitfield, J. B., Pramstaller, P. P., Hicks, A. A., Thompson, J. R. & Minelli, C., Jun 2013, In : PLoS Medicine. 10, 6, e1001462.

Research output: Contribution to journalArticle

Random Allocation
Parkinson Disease
Iron
Serum
Meta-Analysis
46 Citations (Scopus)

Stress-response pathways are altered in the hippocampus of chronic alcoholics

McClintick, J., Xuei, X., Tischfield, J. A., Goate, A., Foroud, T., Wetherill, L., Ehringer, M. A. & Edenberg, H., Nov 2013, In : Alcohol. 47, 7, p. 505-515 11 p.

Research output: Contribution to journalArticle

Alcoholics
alcoholism
Hippocampus
Genes
Alcoholism
5 Citations (Scopus)

The genetics of dementia

Farlow, J. L. & Foroud, T., 2013, In : Seminars in Neurology. 33, 4, p. 417-422 6 p.

Research output: Contribution to journalArticle

Dementia
Genes
Frontotemporal Lobar Degeneration
Exome
Inborn Genetic Diseases
83 Citations (Scopus)

The role of apolipoprotein E (APOE) genotype in early mild cognitive impairment (E-MCI)

Risacher, S. L., Kim, S., Shen, L., Nho, K., Foroud, T., Green, R. C., Petersen, R. C., Jack, C. R., Aisen, P. S., Koeppe, R. A., Jagust, W. J., Shaw, L. M., Trojanowski, J. Q., Weiner, M. W. & Saykin, A., 2013, In : Frontiers in Aging Neuroscience. 5, APR, Article 11.

Research output: Contribution to journalArticle

Apolipoproteins E
Cerebrospinal Fluid
Genotype
Apolipoprotein E4
Amyloid
62 Citations (Scopus)

Two gene co-expression modules differentiate psychotics and controls

Chen, C., Cheng, L., Grennan, K., Pibiri, F., Zhang, C., Badner, J. A., Kelsoe, J. R., Greenwood, T. A., Nievergelt, C. M., Barrett, T. B., McKinney, R., Shilling, P. D., Schork, N. J., Smith, E. N., Bloss, C. S., Nurnberger, J., Edenberg, H., Foroud, T., Koller, D. L., Scheftner, W. & 18 others, Lawson, W. B., Nwulia, E. A., Hipolito, M., Coryell, W., Rice, J., Byerley, W., McMahon, F., Chen, D. T. W., Schulze, T. G., Berrettini, W., Potash, J. B., Zandi, P. P., Mahon, P. B., McInnis, M., Craig, D., Szelinger, S., Gershon, E. S. & Liu, C., Dec 2013, In : Molecular Psychiatry. 18, 12, p. 1308-1314 7 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Schizophrenia
Gene Expression
Neurons
Cerebral Cortex
194 Citations (Scopus)

Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein e ε4, and the risk of late-onset Alzheimer disease in African Americans

Reitz, C., Jun, G., Naj, A., Rajbhandary, R., Vardarajan, B. N., Wang, L. S., Valladares, O., Lin, C. F., Larson, E. B., Graff-Radford, N. R., Evans, D., De Jager, P. L., Crane, P. K., Buxbaum, J. D., Murrell, J. R., Raj, T., Ertekin-Taner, N., Logue, M., Baldwin, C. T., Green, R. C. & 22 others, Barnes, L. L., Cantwell, L. B., Fallin, M. D., Go, R. C. P., Griffith, P., Obisesan, T. O., Manly, J. J., Lunetta, K. L., Kamboh, M. I., Lopez, O. L., Bennett, D. A., Hendrie, H., Hall, K., Goate, A. M., Byrd, G. S., Kukull, W. A., Foroud, T., Haines, J. L., Farrer, L. A., Pericak-Vance, M. A., Schellenberg, G. D. & Mayeux, R., Apr 10 2013, In : Journal of the American Medical Association. 309, 14, p. 1483-1492 10 p.

Research output: Contribution to journalArticle

ATP-Binding Cassette Transporters
Apolipoproteins
African Americans
Alzheimer Disease
Single Nucleotide Polymorphism
48 Citations (Scopus)

Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment

Nho, K., Corneveaux, J. J., Kim, S., Lin, H., Risacher, S. L., Shen, L., Swaminathan, S., Ramanan, V. K., Liu, Y., Foroud, T., Inlow, M. H., Siniard, A. L., Reiman, R. A., Aisen, P. S., Petersen, R. C., Green, R. C., Jack, C. R., Weiner, M. W., Baldwin, C. T., Lunetta, K. & 14 others, Farrer, L. A., Furney, S. J., Lovestone, S., Simmons, A., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., McDonald, B., Farlow, M., Ghetti, B., Huentelman, M. J. & Saykin, A., Jul 2013, In : Molecular Psychiatry. 18, 7, p. 781-787 7 p.

Research output: Contribution to journalArticle

Apolipoprotein E3
Exome
Atrophy
Neuroimaging
Alzheimer Disease
8 Citations (Scopus)

Whole exome sequencing of intracranial aneurysm

Foroud, T., Jan 2013, In : Stroke. 44, SUPPL. 1

Research output: Contribution to journalArticle

Exome
Genome-Wide Association Study
Intracranial Aneurysm
Human Genome
Pedigree
2012
120 Citations (Scopus)

ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry

Bierut, L. J., Goate, A. M., Breslau, N., Johnson, E. O., Bertelsen, S., Fox, L., Agrawal, A., Bucholz, K. K., Grucza, R., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger, J., Porjesz, B., Saccone, N. L., Schuckit, M., Tischfield, J., Wang, J. C., Foroud, T., Rice, J. P. & 1 others, Edenberg, H., Apr 2012, In : Molecular Psychiatry. 17, 4, p. 445-450 6 p.

Research output: Contribution to journalArticle

Alcohol Dehydrogenase
Alcohol Drinking
Alcoholism
Population
Diagnostic and Statistical Manual of Mental Disorders
30 Citations (Scopus)

Amyloid pathway-based candidate gene analysis of [ 11 C]PiB-PET in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort

Swaminathan, S., Shen, L., Risacher, S. L., Yoder, K., West, J. D., Kim, S., Nho, K., Foroud, T., Inlow, M., Potkin, S. G., Huentelman, M. J., Craig, D. W., Jagust, W. J., Koeppe, R. A., Mathis, C. A., Jack, C. R., Weiner, M. W. & Saykin, A., Mar 2012, In : Brain Imaging and Behavior. 6, 1, p. 1-15 15 p.

Research output: Contribution to journalArticle

Genetic Association Studies
Amyloid
Neuroimaging
Alzheimer Disease
Alleles
41 Citations (Scopus)

Analysis of copy number variation in Alzheimer's disease: The NIALOAD/ NCRAD family study

Swaminathan, S., Shen, L., Kim, S., Inlow, M., West, J. D., Faber, K. M., Foroud, T., Mayeux, R. & Saykin, A., 2012, In : Current Alzheimer Research. 9, 7, p. 801-814 14 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Genes
Neuroimaging
DNA Copy Number Variations
Gene Dosage
23 Citations (Scopus)

Analysis of Copy Number Variation in Alzheimer's Disease in a Cohort of Clinically Characterized and Neuropathologically Verified Individuals

Swaminathan, S., Huentelman, M. J., Corneveaux, J. J., Myers, A. J., Faber, K. M., Foroud, T., Mayeux, R., Shen, L., Kim, S., Turk, M., Hardy, J., Reiman, E. M. & Saykin, A., Dec 5 2012, In : PLoS One. 7, 12, e50640.

Research output: Contribution to journalArticle

Alzheimer disease
Alzheimer Disease
Genes
genes
Quality Control
144 Citations (Scopus)

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

Whitcomb, D. C., LaRusch, J., Krasinskas, A. M., Klei, L., Smith, J. P., Brand, R. E., Neoptolemos, J. P., Lerch, M. M., Tector, M., Sandhu, B. S., Guda, N. M., Orlichenko, L., Alkaade, S., Amann, S. T., Anderson, M. A., Baillie, J., Banks, P. A., Conwell, D., Coté, G. A., Cotton, P. B. & 178 others, DiSario, J., Farrer, L. A., Forsmark, C. E., Johnstone, M., Gardner, T. B., Gelrud, A., Greenhalf, W., Haines, J. L., Hartman, D. J., Hawes, R. A., Lawrence, C., Lewis, M., Mayerle, J., Mayeux, R., Melhem, N. M., Money, M. E., Muniraj, T., Papachristou, G. I., Pericak-Vance, M. A., Romagnuolo, J., Schellenberg, G. D., Sherman, S., Simon, P., Singh, V. P., Slivka, A., Stolz, D., Sutton, R., Weiss, F. U., Wilcox, C. M., Zarnescu, N. O., Wisniewski, S. R., O'Connell, M. R., Kienholz, M. L., Roeder, K., Barmada, M. M., Yadav, D., Devlin, B., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Baldwin, C. T., Barber, R., Barnes, L. L., Beach, T. G., Beecham, G. W., Beekly, D., Bennett, D. A., Bigio, E. H., Bird, T. D., Blacker, D., Boxer, A., Burke, J. R., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carney, R. M., Carroll, S. L., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Cruchaga, C., DeCarli, C., Demirci, F. Y., Dick, M., Dickson, D. W., Duara, R., Ertekin-Taner, N., Faber, K. M., Fallon, K. B., Farlow, M., Ferris, S., Foroud, T., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Glass, J. D., Goate, A. M., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton-Nelson, K. L., Hamilton, R. L., Harrell, L. E., Head, E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jicha, G. A., Jin, L. W., Jun, G., Kamboh, M. I., Karydas, A., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., Kramer, P., Kukul, W. A., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lin, C. F., Lieberman, A. P., Lopez, O. L., Lunetta, K. L., Lyketsos, C. G., MacK, W. J., Marson, D. C., Martin, E. R., Martiniuk, F., Mash, D. C., Masliah, E., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Murrel, J. R., Naj, A. C., Olichney, J. M., Parisi, J. E., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rosen, H. J., Rosenberg, R. N., Sano, M., Saykin, A., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Valladares, O., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsatte, J. P., Wang, L. S., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E. & Yu, L., Dec 2012, In : Nature Genetics. 44, 12, p. 1349-1354 6 p.

Research output: Contribution to journalArticle

Pancreatitis
Alcohols
Claudin-2
Hemizygote
Alleles
19 Citations (Scopus)
Saccades
Huntington Disease
Gray Matter
Parietal Lobe
Caudate Nucleus
350 Citations (Scopus)

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDgene database

Lill, C. M., Roehr, J. T., McQueen, M. B., Kavvoura, F. K., Bagade, S., Schjeide, B. M. M., Schjeide, L. M., Meissner, E., Zauft, U., Allen, N. C., Liu, T., Schilling, M., Anderson, K. J., Beecham, G., Berg, D., Biernacka, J. M., Brice, A., DeStefano, A. L., Do, C. B., Eriksson, N. & 34 others, Factor, S. A., Farrer, M. J., Foroud, T., Gasser, T., Hamza, T., Hardy, J. A., Heutink, P., Hill-Burns, E. M., Klein, C., Latourelle, J. C., Maraganore, D. M., Martin, E. R., Martinez, M., Myers, R. H., Nalls, M. A., Pankratz, N., Payami, H., Satake, W., Scott, W. K., Sharma, M., Singleton, A. B., Stefansson, K., Toda, T., Tung, J. Y., Vance, J., Wood, N. W., Zabetian, C. P., Young, P., Tanzi, R. E., Khoury, M. J., Zipp, F., Lehrach, H., Ioannidis, J. P. A. & Bertram, L., Mar 2012, In : PLoS Genetics. 8, 3, e1002548.

Research output: Contribution to journalArticle

Parkinson disease
Parkinson Disease
Meta-Analysis
Genome-Wide Association Study
genome
103 Citations (Scopus)

Copy-number disorders are a common cause of congenital kidney malformations

Sanna-Cherchi, S., Kiryluk, K., Burgess, K. E., Bodria, M., Sampson, M. G., Hadley, D., Nees, S. N., Verbitsky, M., Perry, B. J., Sterken, R., Lozanovski, V. J., Materna-Kiryluk, A., Barlassina, C., Kini, A., Corbani, V., Carrea, A., Somenzi, D., Murtas, C., Ristoska-Bojkovska, N., Izzi, C. & 36 others, Bianco, B., Zaniew, M., Flogelova, H., Weng, P. L., Kacak, N., Giberti, S., Gigante, M., Arapovic, A., Drnasin, K., Caridi, G., Curioni, S., Allegri, F., Ammenti, A., Ferretti, S., Goj, V., Bernardo, L., Jobanputra, V., Chung, W. K., Lifton, R. P., Sanders, S., State, M., Clark, L. N., Saraga, M., Padmanabhan, S., Dominiczak, A. F., Foroud, T., Gesualdo, L., Gucev, Z., Allegri, L., Latos-Bielenska, A., Cusi, D., Scolari, F., Tasic, V., Hakonarson, H., Ghiggeri, G. M. & Gharavi, A. G., Dec 7 2012, In : American Journal of Human Genetics. 91, 6, p. 987-997 11 p.

Research output: Contribution to journalArticle

Kidney
Population Control
Gene Dosage
Urinary Tract
Databases
126 Citations (Scopus)

Evidence for a role of the rare p.A152T variant in mapt in increasing the risk for FTD-spectrum and Alzheimer's diseases

Coppola, G., Chinnathambi, S., Lee, J. J., Dombroski, B. A., Baker, M. C., Soto-ortolaza, A. I., Lee, S. E., Klein, E., Huang, A. Y., Sears, R., Lane, J. R., Karydas, A. M., Kenet, R. O., Biernat, J., Wang, L. S., Cotman, C. W., Decarli, C. S., Levey, A. I., Ringman, J. M., Mendez, M. F. & 210 others, Chui, H. C., Le ber, I., Brice, A., Lupton, M. K., Preza, E., Lovestone, S., Powell, J., Graff-radford, N., Petersen, R. C., Boeve, B. F., Lippa, C. F., Bigio, E. H., Mackenzie, I., Finger, E., Kertesz, A., Caselli, R. J., Gearing, M., Juncos, J. L., Ghetti, B., Spina, S., Bordelon, Y. M., Tourtellotte, W. W., Frosch, M. P., Vonsattel, J. P. G., Zarow, C., Beach, T. G., Albin, R. L., Lieberman, A. P., Lee, V. M., Trojanowski, J. Q., Van deerlin, V. M., Bird, T. D., Galasko, D. R., Masliah, E., White, C. L., Troncoso, J. C., Hannequin, D., Boxer, A. L., Geschwind, M. D., Kumar, S., Mandelkow, E. M., Wszolek, Z. K., Uitti, R. J., Dickson, D. W., Haines, J. L., Mayeux, R., Pericak-vance, M. A., Farrer, L. A., Apostolova, L. G., Arnold, S. E., Baldwin, C. T., Barber, R., Barmada, M. M., Beach, T., Beecham, G. W., Beekly, D., Bennett, D. A., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Buros, J., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carlson, C. S., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cotman, C. W., Crane, P. K., Cruchaga, C., Cummings, J. L., De Jager, P. L., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Diaz-Arrastia, R., Dick, M., Dickson, D. W., Dombroski, B. A., Duara, R., Ellis, W. G., Ertekin-Taner, N. N., Evans, D., Faber, K. M., Fallon, K. B., Farlow, M., Ferris, S., Foroud, T., Frosch, M. P., Galasko, D. R., Gallins, P. J., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Giordani, B., Glass, J. D., Goate, A. M., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Hardy, J., Harrell, L. E., Head, E., Honig, L. S., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Johnson, N., Jun, G., Kamboh, M. I., Karlawish, J., Karydas, A., Kauwe, J. S. K., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, P., Kukull, W. A., Lah, J. J., Larson, E. B., Levey, A. I., Lieberman, A. P., Lopez, O. L., Lunetta, K. L., Mack, W. J., Marson, D. C., Martin, E. R., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Myers, A. J., Naj, A. C., Nowotny, P., Parisi, J. E., Perl, D. P., Peskind, E., Petersen, R. C., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Rajbhandary, R. A., Raskind, M., Reiman, E. M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosenberg, R. N., Sano, M., Saykin, A., Schneider, J. A., Schneider, L. S., Seeley, W., Shelanski, M. L., Slifer, M. A., Smith, C. D., Sonnen, J. A., Spina, S., George-Hyslop, P. S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Wang, L. S., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Younkin, S. G., Ross, O. A., Rademakers, R., Schellenberg, G. D., Miller, B. L., Mandelkow, E. & Geschwind, D. H., 2012, In : Human Molecular Genetics. 21, 15, p. 3500-3512 13 p., dds161.

Research output: Contribution to journalArticle

Progressive Supranuclear Palsy
Frontotemporal Dementia
Microtubule-Associated Proteins
Microtubules
tau Proteins
40 Citations (Scopus)

Family-based genome-wide association study of frontal theta oscillations identifies potassium channel gene KCNJ6

Kang, S. J., Rangaswamy, M., Manz, N., Wang, J. C., Wetherill, L., Hinrichs, T., Almasy, L., Brooks, A., Chorlian, D. B., Dick, D., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger, J., Rice, J., Schuckit, M., Tischfield, J., Bierut, L. J., Edenberg, H., Goate, A. & 2 others, Foroud, T. & Porjesz, B., Aug 2012, In : Genes, Brain and Behavior. 11, 6, p. 712-719 8 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Potassium Channels
Single Nucleotide Polymorphism
Alcoholism
Genes
40 Citations (Scopus)

Gene expression profiles in Parkinson disease prefrontal cortex implicate FOXO1 and genes under its transcriptional regulation

Dumitriu, A., Latourelle, J. C., Hadzi, T. C., Pankratz, N., Garza, D., Miller, J. P., Vance, J. M., Foroud, T., Beach, T. G. & Myers, R. H., Jun 2012, In : PLoS Genetics. 8, 6, e1002794.

Research output: Contribution to journalArticle

Parkinson disease
Prefrontal Cortex
Transcriptome
gene expression
Parkinson Disease
72 Citations (Scopus)

Genome-wide association study of intracranial aneurysms confirms role of anril and SOX17 in disease risk

Foroud, T., Koller, D. L., Lai, D., Sauerbeck, L., Anderson, C., Ko, N., Deka, R., Mosley, T. H., Fornage, M., Woo, D., Moomaw, C. J., Hornung, R., Huston, J., Meissner, I., Baileywilson, J. E., Langefeld, C., Rouleau, G., Sander Connolly, E., Worrall, B. B., Kleindorfer, D. & 6 others, Flaherty, M. L., Martini, S., Mackey, J., De Los Rios La Rosa, F., Brown, R. D. & Broderick, J. P., Nov 2012, In : Stroke. 43, 11, p. 2846-2852 7 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Intracranial Aneurysm
Single Nucleotide Polymorphism
Chromosomes
Logistic Models
19 Citations (Scopus)

Genome-wide linkage analysis of 972 bipolar pedigrees using single-nucleotide polymorphisms

Badner, J. A., Koller, D., Foroud, T., Edenberg, H., Nurnberger, J., Zandi, P. P., Willour, V. L., McMahon, F. J., Potash, J. B., Hamshere, M., Grozeva, D., Green, E., Kirov, G., Jones, I., Jones, L., Craddock, N., Morris, D., Segurado, R., Gill, M., Sadovnick, D. & 13 others, Remick, R., Keck, P., Kelsoe, J., Ayub, M., MacLean, A., Blackwood, D., Liu, C. Y., Gershon, E. S., McMahon, W., Lyon, G. J., Robinson, R., Ross, J. & Byerley, W., Aug 2012, In : Molecular Psychiatry. 17, 8, p. 818-826 9 p.

Research output: Contribution to journalArticle

Pedigree
Bipolar Disorder
Single Nucleotide Polymorphism
Genome
Depression
44 Citations (Scopus)

Genome-wide pathway analysis of memory impairment in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort implicates gene candidates, canonical pathways, and networks

Ramanan, V. K., Kim, S., Holohan, K., Shen, L., Nho, K., Risacher, S. L., Foroud, T., Mukherjee, S., Crane, P. K., Aisen, P. S., Petersen, R. C., Weiner, M. W. & Saykin, A., 2012, In : Brain Imaging and Behavior. 6, 4, p. 634-648 15 p.

Research output: Contribution to journalArticle

Neuroimaging
Alzheimer Disease
Genome
Genes
Memory Disorders
66 Citations (Scopus)

Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory

Barral, S., Bird, T., Goate, A., Farlow, M., Diaz-Arrastia, R., Bennett, D. A., Graff-Radford, N., Boeve, B. F., Sweet, R. A., Stern, Y., Wilson, R. S., Foroud, T., Ott, J. & Mayeux, R., May 8 2012, In : Neurology. 78, 19, p. 1464-1471 8 p.

Research output: Contribution to journalArticle

Episodic Memory
Alzheimer Disease
Genotype
Single Nucleotide Polymorphism
Genes
388 Citations (Scopus)

Identification of common variants associated with human hippocampal and intracranial volumes

Stein, J. L., Medland, S. E., Vasquez, A. A., Hibar, D. P., Senstad, R. E., Winkler, A. M., Toro, R., Appel, K., Bartecek, R., Bergmann, Ø., Bernard, M., Brown, A. A., Cannon, D. M., Chakravarty, M. M., Christoforou, A., Domin, M., Grimm, O., Hollinshead, M., Holmes, A. J., Homuth, G. & 182 others, Hottenga, J. J., Langan, C., Lopez, L. M., Hansell, N. K., Hwang, K. S., Kim, S., Laje, G., Lee, P. H., Liu, X., Loth, E., Lourdusamy, A., Mattingsdal, M., Mohnke, S., Maniega, S. M., Nho, K., Nugent, A. C., O'brien, C., Papmeyer, M., Pütz, B., Ramasamy, A., Rasmussen, J., Rijpkema, M., Risacher, S. L., Roddey, J. C., Rose, E. J., Ryten, M., Shen, L., Sprooten, E., Strengman, E., Teumer, A., Trabzuni, D., Turner, J., Van Eijk, K., Van Erp, T. G. M., Van Tol, M. J., Wittfeld, K., Wolf, C., Woudstra, S., Aleman, A., Alhusaini, S., Almasy, L., Binder, E. B., Brohawn, D. G., Cantor, R. M., Carless, M. A., Corvin, A., Czisch, M., Curran, J. E., Davies, G., De Almeida, M. A. A., Delanty, N., Depondt, C., Duggirala, R., Dyer, T. D., Erk, S., Fagerness, J., Fox, P. T., Freimer, N. B., Gill, M., Göring, H. H. H., Hagler, D. J., Hoehn, D., Holsboer, F., Hoogman, M., Hosten, N., Jahanshad, N., Johnson, M. P., Kasperaviciute, D., Kent, J. W., Kochunov, P., Lancaster, J. L., Lawrie, S. M., Liewald, D. C., Mandl, R., Matarin, M., Mattheisen, M., Meisenzahl, E., Melle, I., Moses, E. K., Mühleisen, T. W., Nauck, M., Nöthen, M. M., Olvera, R. L., Pandolfo, M., Pike, G. B., Puls, R., Reinvang, I., Rentería, M. E., Rietschel, M., Roffman, J. L., Royle, N. A., Rujescu, D., Savitz, J., Schnack, H. G., Schnell, K., Seiferth, N., Smith, C., Steen, V. M., Hernández, M. C. V., Van Den Heuvel, M., Van Der Wee, N. J., Van Haren, N. E. M., Veltman, J. A., Völzke, H., Walker, R., Westlye, L. T., Whelan, C. D., Agartz, I., Boomsma, D. I., Cavalleri, G. L., Dale, A. M., Djurovic, S., Drevets, W. C., Hagoort, P., Hall, J., Heinz, A., Jack, C. R., Foroud, T., Le Hellard, S., Macciardi, F., Montgomery, G. W., Poline, J. B., Porteous, D. J., Sisodiya, S. M., Starr, J. M., Sussmann, J., Toga, A. W., Veltman, D. J., Walter, H., Weiner, M. W., Bis, J. C., Ikram, M. A., Smith, A. V., Gudnason, V., Tzourio, C., Vernooij, M. W., Launer, L. J., Decarli, C., Seshadri, S., Andreassen, O. A., Apostolova, L. G., Bastin, M. E., Blangero, J., Brunner, H. G., Buckner, R. L., Cichon, S., Coppola, G., De Zubicaray, G. I., Deary, I. J., Donohoe, G., De Geus, E. J. C., Espeseth, T., Fernéndez, G., Glahn, D. C., Grabe, H. J., Hardy, J., Hulshoff Pol, H. E., Jenkinson, M., Kahn, R. S., Mcdonald, C., Mcintosh, A. M., Mcmahon, F. J., Mcmahon, K. L., Meyer-Lindenberg, A., Morris, D. W., Müller-Myhsok, B., Nichols, T. E., Ophoff, R. A., Paus, T., Pausova, Z., Penninx, B. W., Potkin, S. G., Sämann, P. G., Saykin, A., Schumann, G., Smoller, J. W., Wardlaw, J. M., Weale, M. E., Martin, N. G., Franke, B., Wright, M. J. & Thompson, P. M., May 2012, In : Nature Genetics. 44, 5, p. 552-561 10 p.

Research output: Contribution to journalArticle

Brain
Temporal Lobe Epilepsy
Genome-Wide Association Study
Neuroimaging
Cognition
47 Citations (Scopus)

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

Hartz, S. M., Short, S. E., Saccone, N. L., Culverhouse, R., Chen, L., Schwantes-An, T. H., Coon, H., Han, Y., Stephens, S. H., Sun, J., Chen, X., Ducci, F., Dueker, N., Franceschini, N., Frank, J., Geller, F., Guobjartsson, D., Hansel, N. N., Jiang, C., Keskitalo-Vuokko, K. & 132 others, Liu, Z., Lyytikäinen, L. P., Michel, M., Rawal, R., Rosenberger, A., Scheet, P., Shaffer, J. R., Teumer, A., Thompson, J. R., Vink, J. M., Vogelzangs, N., Wenzlaff, A. S., Wheeler, W., Xiao, X., Yang, B. Z., Aggen, S. H., Balmforth, A. J., Baumeister, S. E., Beaty, T., Bennett, S., Bergen, A. W., Boyd, H. A., Broms, U., Campbell, H., Chatterjee, N., Chen, J., Cheng, Y. C., Cichon, S., Couper, D., Cucca, F., Dick, D. M., Foroud, T., Furberg, H., Giegling, I., Gu, F., Hall, A. S., Hällfors, J., Han, S., Hartmann, A. M., Hayward, C., Heikkilä, K., Hewitt, J. K., Hottenga, J. J., Jensen, M. K., Jousilahti, P., Kaakinen, M., Kittner, S. J., Konte, B., Korhonen, T., Landi, M. T., Laatikainen, T., Leppert, M., Levy, S. M., Mathias, R. A., McNeil, D. W., Medland, S. E., Montgomery, G. W., Muley, T., Murray, T., Nauck, M., North, K., Pergadia, M., Polasek, O., Ramos, E. M., Ripatti, S., Risch, A., Ruczinski, I., Rudan, I., Salomaa, V., Schlessinger, D., Styrkársdóttir, U., Terracciano, A., Uda, M., Willemsen, G., Wu, X., Abecasis, G., Barnes, K., Bickeböller, H., Boerwinkle, E., Boomsma, D. I., Caporaso, N., Duan, J., Edenberg, H., Francks, C., Gejman, P. V., Gelernter, J., Grabe, H. J., Hops, H., Jarvelin, M. R., Viikari, J., Kähönen, M., Kendler, K. S., Lehtimäki, T., Levinson, D. F., Marazita, M. L., Marchini, J., Melbye, M., Mitchell, B. D., Murray, J. C., Nöthen, M. M., Penninx, B. W., Raitakari, O., Rietschel, M., Rujescu, D., Samani, N. J., Sanders, A. R., Schwartz, A. G., Shete, S., Shi, J., Spitz, M., Stefansson, K., Swan, G. E., Thorgeirsson, T., Völzke, H., Wei, Q., Wichmann, H. E., Amos, C. I., Breslau, N., Cannon, D. S., Ehringer, M., Grucza, R., Hatsukami, D., Heath, A., Johnson, E. O., Kaprio, J., Madden, P., Martin, N. G., Stevens, V. L., Stitzel, J. A., Weiss, R. B., Kraft, P. & Bierut, L. J., Aug 2012, In : Archives of General Psychiatry. 69, 8, p. 854-861 8 p.

Research output: Contribution to journalArticle

Age of Onset
Tobacco Products
Smoking
Alleles
Odds Ratio
150 Citations (Scopus)

Meta-analysis of Parkinson's Disease: Identification of a novel locus, RIT2

Pankratz, N., Beecham, G. W., Destefano, A. L., Dawson, T. M., Doheny, K. F., Factor, S. A., Hamza, T. H., Hung, A. Y., Hyman, B. T., Ivinson, A. J., Krainc, D., Latourelle, J. C., Clark, L. N., Marder, K., Martin, E. R., Mayeux, R., Ross, O. A., Scherzer, C. R., Simon, D. K., Tanner, C. & 7 others, Vance, J. M., Wszolek, Z. K., Zabetian, C. P., Myers, R. H., Payami, H., Scott, W. K. & Foroud, T., Mar 2012, In : Annals of Neurology. 71, 3, p. 370-384 15 p.

Research output: Contribution to journalArticle

Parkinson Disease
Meta-Analysis
Odds Ratio
Disease Susceptibility
Single Nucleotide Polymorphism
164 Citations (Scopus)

Rare variants in APP, PSEN1 and PSEN2 increase risk for AD in late-onset Alzheimer's disease families

Cruchaga, C., Chakraverty, S., Mayo, K., Vallania, F. L. M., Mitra, R. D., Faber, K., Williamson, J., Bird, T., Diaz-Arrastia, R., Foroud, T., Boeve, B. F., Graff-Radford, N. R., St. Jean, P., Lawson, M., Ehm, M. G., Mayeux, R., Goate, A. M. & for the NIA-LOAD - NCRAD Family Study Consortium, T. NIA-LOAD. . NCRAD. F. S. C., Feb 1 2012, In : PLoS One. 7, 2, e31039.

Research output: Contribution to journalArticle

Alzheimer disease
Alzheimer Disease
Genes
mutation
Mutation
7 Citations (Scopus)

Regsnps: A strategy for prioritizing regulatory single nucleotide substitutions

Teng, M., Ichikawa, S., Padgett, L. R., Wang, Y., Mort, M., Cooper, D. N., Koller, D. L., Foroud, T., Edenberg, H., Econs, M. & Liu, Y., Jul 2012, In : Bioinformatics. 28, 14, p. 1879-1886 8 p., bts275.

Research output: Contribution to journalArticle

Nucleotides
Single Nucleotide Polymorphism
Substitution
Informatics
Substitution reactions