Tatiana Foroud

  • 40289 Citations
  • 101 h-Index
1976 …2021
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Publications 1988 2019

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2016
8 Citations (Scopus)

Integration of bioinformatics and imaging informatics for identifying rare PSEN1 variants in Alzheimer's disease

Nho, K., Horgusluoglu, E., Kim, S., Risacher, S. L., Kim, D., Foroud, T., Aisen, P. S., Petersen, R. C., Jack, C. R., Shaw, L. M., Trojanowski, J. Q., Weiner, M. W., Green, R. C., Toga, A. W. & Saykin, A., Aug 12 2016, In : BMC Medical Genomics. 9, 30.

Research output: Contribution to journalArticle

Informatics
Computational Biology
Endophenotypes
Cerebrospinal Fluid
Alzheimer Disease
17 Citations (Scopus)

NIPT and Informed Consent: an Assessment of Patient Understanding of a Negative NIPT Result

Piechan, J. L., Hines, K. A., Koller, D. L., Stone, K., Quaid, K., Torres-Martinez, W., Wilson Mathews, D., Foroud, T. & Cook, L., Apr 1 2016, (Accepted/In press) In : Journal of Genetic Counseling. p. 1-11 11 p.

Research output: Contribution to journalArticle

Informed Consent
Aneuploidy
Patient Education
Down Syndrome
Pregnant Women
61 Citations (Scopus)

Novel genetic loci underlying human intracranial volume identified through genome-wide association

Adams, H. H. H., Hibar, D. P., Chouraki, V., Stein, J. L., Nyquist, P. A., Rentería, M. E., Trompet, S., Arias-Vasquez, A., Seshadri, S., Desrivières, S., Beecham, A. H., Jahanshad, N., Wittfeld, K., van der Lee, S. J., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S. & 322 others, Armstrong, N. J., Athanasiu, L., Axelsson, T., Beiser, A., Bernard, M., Bis, J. C., Blanken, L. M. E., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chauhan, G., Chen, Q., Ching, C. R. K., Cuellar-Partida, G., Braber, A. D., Doan, N. T., Ehrlich, S., Filippi, I., Ge, T., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Greven, C. U., Grimm, O., Griswold, M. E., Guadalupe, T., Hass, J., Haukvik, U. K., Hilal, S., Hofer, E., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liao, J., Liewald, D. C. M., Lopez, L. M., Luciano, M., Macare, C., Marquand, A., Matarin, M., Mather, K. A., Mattheisen, M., Mazoyer, B., McKay, D. R., McWhirter, R., Milaneschi, Y., Mirza-Schreiber, N., Muetzel, R. L., Maniega, S. M., Nho, K., Nugent, A. C., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pappa, I., Pirpamer, L., Pudas, S., Pütz, B., Rajan, K. B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-Santiañez, R., Rommelse, N., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Thomson, R., Tordesillas-Gutierrez, D., Toro, R., Trabzuni, D., Vaidya, D., van der Grond, J., van der Meer, D., van Donkelaar, M. M. J., van Eijk, K. R., van Erp, T. G. M., van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Woldehawariat, G., Wolf, C., Wolfers, T., Xu, B., Yanek, L. R., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Aggarwal, N. T., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Chen, C., Cheng, C. Y., Cichon, S., Cookson, M. R., Corvin, A., Crespo-Facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., de Geus, E. J. C., de Jager, P. L., de Zubicaray, G. I., Delanty, N., Depondt, C., DeStefano, A. L., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Erk, S., Espeseth, T., Evans, D. A., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Foroud, T. M., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Grabe, H. J., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B. C., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J. J., Pol, H. E. H., Ikeda, M., Ikram, M. K., Jr, C. R. J., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Jr, W. T. L., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J. L., Mattay, V. S., McDonald, C., McIntosh, A. M., McMahon, K. L., McMahon, F. J., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Potkin, S. G., Psaty, B. M., Reppermund, S., Rietschel, M., Roffman, J. L., Romanczuk-Seiferth, N., Rotter, J. I., Ryten, M., Sacco, R. L., Sachdev, P. S., Saykin, A. J., Schmidt, R., Schofield, P. R., Sigurdsson, S., Simmons, A., Singleton, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soininen, H., Srikanth, V., Steen, V. M., Stott, D. J., Sussmann, J. E., Thalamuthu, A., Tiemeier, H., Toga, A. W., Traynor, B. J., Troncoso, J., Turner, J. A., Tzourio, C., Uitterlinden, A. G., Hernández, M. C. V., van der Brug, M., van der Lugt, A., van der Wee, N. J. A., van Duijn, C. M., van Haren, N. E. M., van ′t Ent, D., van Tol, M. J., Vardarajan, B. N., Veltman, D. J., Vernooij, M. W., Völzke, H., Walter, H., Wardlaw, J. M., Wassink, T. H., Weale, M. E., Weinberger, D. R., Weiner, M. W., Wen, W., Westman, E., White, T., Wong, T. Y., Wright, C. B., Zielke, H. R., Zonderman, A. B., Deary, I. J., DeCarli, C., Schmidt, H., Martin, N. G., de Craen, A. J. M., Wright, M. J., Launer, L. J., Schumann, G., Fornage, M., Franke, B., Debette, S., Medland, S. E., Ikram, M. A. & Thompson, P. M., Oct 3 2016, (Accepted/In press) In : Nature Neuroscience.

Research output: Contribution to journalArticle

Genetic Loci
Genome
Genome-Wide Association Study
Phosphatidylinositol 3-Kinases
Cognition
14 Citations (Scopus)

Shared genetic contribution to ischemic stroke and Alzheimer's disease

Traylor, M., Adib-Samii, P., Harold, D., Dichgans, M., Williams, J., Lewis, C. M., Markus, H. S., Fornage, M., Holliday, E. G., Sharma, P., Bis, J. C., Psaty, B. M., Seshadri, S., Nalls, M. A., Devan, W. J., Boncoraglio, G., Malik, R., Mitchell, B. D., Kittner, S. J., Ikram, M. A. & 188 others, Clarke, R., Rosand, J., Meschia, J. F., Sudlow, C., Rothwell, P. M., Levi, C., Bevan, S., Kilarski, L. L., Walters, M., Thijs, V., Slowik, A., Lindgren, A., De Bakker, P. I. W., Lambert, J. C., Ibrahim-Verbaas, C. A., Naj, A. C., Sims, R., Bellenguez, C., Jun, G., Destefano, A. L., Beecham, G. W., Grenier-Boley, B., Russo, G., Thornton-Wells, T. A., Jones, N., Smith, A. V., Chouraki, V., Thomas, C., Zelenika, D., Vardarajan, B. N., Kamatani, Y., Lin, C. F., Gerrish, A., Schmidt, H., Kunkle, B., Dunstan, M. L., Ruiz, A., Bihoreau, M. T., Choi, S. H., Reitz, C., Pasquier, F., Hollingworth, P., Ramirez, A., Hanon, O., Fitzpatrick, A. L., Buxbaum, J. D., Campion, D., Crane, P. K., Baldwin, C., Becker, T., Gudnason, V., Cruchaga, C., Craig, D., Amin, N., Berr, C., Lopez, O. L., De Jager, P. L., Deramecourt, V., Johnston, J. A., Evans, D., Lovestone, S., Letenneur, L., Morón, F. J., Rubinsztein, D. C., Eiriksdottir, G., Sleegers, K., Goate, A. M., Fiçvet, N., Huentelman, M. J., Gill, M., Brown, K., Kamboh, M. I., Keller, L., Barberger-Gateau, P., McGuinness, B., Larson, E. B., Green, R., Myers, A. J., Dufouil, C., Todd, S., Wallon, D., Love, S., Rogaeva, E., Gallacher, J., St George-Hyslop, P., Clarimon, J., Lleo, A., Bayer, A., Tsuang, D. W., Yu, L., Tsolaki, M., Bossù, P., Spalletta, G., Proitsi, P., Collinge, J., Sorbi, S., Sanchez-Garcia, F., Fox, N. C., Hardy, J., Deniz Naranjo, M. C., Bosco, P., Brayne, C., Galimberti, D., Mancuso, M., Matthews, F., Moebus, S., Mecocci, P., Del Zompo, M., Maier, W., Hampel, H., Pilotto, A., Bullido, M., Panza, F., Caffarra, P., Nacmias, B., Gilbert, J. R., Mayhaus, M., Lannfelt, L., Hakonarson, H., Pichler, S., Carrasquillo, M. M., Ingelsson, M., Beekly, D., Alvarez, V., Zou, F., Valladares, O., Younkin, S. G., Coto, E., Hamilton-Nelson, K. L., Gu, W., Razquin, C., Pastor, P., Mateo, I., Owen, M. J., Faber, K. M., Jonsson, P. V., Combarros, O., O'Donovan, M. C., Cantwell, L. B., Soininen, H., Blacker, D., Mead, S., Mosley, T. H., Bennett, D. A., Harris, T. B., Fratiglioni, L., Holmes, C., De Bruijn, R. F. A. G., Passmore, P., Montine, T. J., Bettens, K., Rotter, J. I., Brice, A., Morgan, K., Foroud, T. M., Kukull, W. A., Hannequin, D., Powell, J. F., Nalls, M. A., Ritchie, K., Lunetta, K. L., Kauwe, J. S. K., Boerwinkle, E., Riemenschneider, M., Boada, M., Hiltunen, M., Martin, E. R., Schmidt, R., Rujescu, D., Wang, L. S., Dartigues, J. F., Mayeux, R., Tzourio, C., Hofman, A., Nöthen, M. M., Graff, C., Jones, L., Haines, J. L., Holmans, P. A., Lathrop, M., Pericak-Vance, M. A., Launer, L. J., Farrer, L. A., Van Duijn, C. M., Van Broeckhoven, C., Moskvina, V., Schellenberg, G. D. & Amouyel, P., May 1 2016, In : Annals of Neurology. 79, 5, p. 739-747 9 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Stroke
Genome-Wide Association Study
Single Nucleotide Polymorphism
Meta-Analysis
10 Citations (Scopus)

Shared genetic risk factors of intracranial, abdominal, and thoracic aneurysms

Aneurysm Consortium, Vascular Research Consortium of New Zealand, Jul 1 2016, In : Journal of the American Heart Association. 5, 7, e002603.

Research output: Contribution to journalArticle

Abdominal Aortic Aneurysm
Thoracic Aortic Aneurysm
Intracranial Aneurysm
Aneurysm
Thorax
19 Citations (Scopus)

The role of cardiovascular risk factors and stroke in familial Alzheimer disease

Tosto, G., Bird, T. D., Bennett, D. A., Boeve, B. F., Brickman, A. M., Cruchaga, C., Faber, K., Foroud, T., Farlow, M., Goate, A. M., Graff-Radford, N. R., Lantigua, R., Manly, J., Ottman, R., Rosenberg, R., Schaid, D. J., Schupf, N., Stern, Y., Sweet, R. A. & Mayeux, R., Oct 1 2016, In : JAMA Neurology. 73, 10, p. 1231-1237 7 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Stroke
Odds Ratio
Apolipoprotein E4
Cardiovascular Diseases
25 Citations (Scopus)

Whole-exome sequencing in familial Parkinson disease

Farlow, J. L., Robak, L. A., Hetrick, K., Bowling, K., Boerwinkle, E., Coban-Akdemir, Z. H., Gambin, T., Gibbs, R. A., Gu, S., Jain, P., Jankovic, J., Jhangiani, S., Kaw, K., Lai, D., Lin, H., Ling, H., Liu, Y., Lupski, J. R., Muzny, D., Porter, P. & 6 others, Pugh, E., White, J., Doheny, K., Myers, R. M., Shulman, J. M. & Foroud, T., Jan 1 2016, In : JAMA Neurology. 73, 1, p. 68-75 8 p.

Research output: Contribution to journalArticle

Exome
Parkinson Disease
Genes
Age of Onset
Disease Susceptibility
2015
11 Citations (Scopus)
Drinking
Genotype
Alcohols
Alcoholism
Single Nucleotide Polymorphism
31 Citations (Scopus)

A description of the methods of the Nulliparous Pregnancy Outcomes Study: Monitoring mothers-to-be (nuMoM2b)

Haas, D., Parker, C. B., Wing, D. A., Parry, S., Grobman, W. A., Mercer, B. M., Simhan, H. N., Hoffman, M. K., Silver, R. M., Wadhwa, P., Iams, J. D., Koch, M. A., Caritis, S. N., Wapner, R. J., Esplin, M. S., Elovitz, M. A., Foroud, T., Peaceman, A. M., Saade, G. R., Willinger, M. & 1 others, Reddy, U. M., Apr 1 2015, In : American Journal of Obstetrics and Gynecology. 212, 4, p. 539.e1-539.e24

Research output: Contribution to journalArticle

Pregnancy Outcome
Mothers
Outcome Assessment (Health Care)
Pregnancy
Cohort Studies
7 Citations (Scopus)

Affected twins in the familial intracranial aneurysm study

Mackey, J., Brown, R. D., Sauerbeck, L., Hornung, R., Moomaw, C. J., Koller, D. L., Foroud, T., Deka, R., Woo, D., Kleindorfer, D., Flaherty, M. L., Meissner, I., Anderson, C., Rouleau, G., Connolly, E. S., Huston, J. & Broderick, J. P., Mar 6 2015, In : Cerebrovascular Diseases. 39, 2, p. 82-86 5 p.

Research output: Contribution to journalArticle

Intracranial Aneurysm
Dizygotic Twins
Monozygotic Twins
Rupture
Aneurysm
3 Citations (Scopus)

A genome wide association study of fast beta EEG in families of European ancestry

Meyers, J. L., Zhang, J., Manz, N., Rangaswamy, M., Kamarajan, C., Wetherill, L., Chorlian, D. B., Kang, S. J., Bauer, L., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger, J., Tischfield, J., Wang, J. C., Edenberg, H., Goate, A., Foroud, T. & Porjesz, B., Sep 15 2015, (Accepted/In press) In : International Journal of Psychophysiology.

Research output: Contribution to journalArticle

Racemases and Epimerases
Genome-Wide Association Study
Dermatan Sulfate
Electroencephalography
Genes
36 Citations (Scopus)

AluY-mediated germline deletion, duplication and somatic stem cell reversion in UBE2T defines a new subtype of Fanconi anemia

Virts, E. L., Jankowska, A., Mackay, C., Glaas, M. F., Wiek, C., Kelich, S. L., Lottmann, N., Kennedy, F. M., Marchal, C., Lehnert, E., Scharf, R. E., Dufour, C., Lanciotti, M., Farruggia, P., Santoro, A., Savasan, S., Scheckenbach, K., Schipper, J., Wagenmann, M., Lewis, T. & 12 others, Leffak, M., Farlow, J. L., Foroud, T., Honisch, E., Niederacher, D., Chakraborty, S. C., Vance, G., Pruss, D., Timms, K. M., Lanchbury, J. S., Alpi, A. F. & Hanenberg, H., Apr 9 2015, In : Human Molecular Genetics. 24, 18, p. 5093-5108 16 p., ddv227.

Research output: Contribution to journalArticle

Fanconi Anemia
Adult Stem Cells
Exons
Germ-Line Mutation
Mothers
18 Citations (Scopus)

A multiancestral genome-wide exome array study of Alzheimer Disease, frontotemporal dementia, and progressive supranuclear palsy

Chen, J. A., Wang, Q., Davis-Turak, J., Li, Y., Karydas, A. M., Hsu, S. C., Sears, R. L., Chatzopoulou, D., Huang, A. Y., Wojta, K. J., Klein, E., Lee, J., Beekly, D. L., Boxer, A., Faber, K. M., Haase, C. M., Miller, J., Poon, W. W., Rosen, A., Rosen, H. & 15 others, Sapozhnikova, A., Shapira, J., Varpetian, A., Foroud, T., Levenson, R. W., Levey, A. I., Kukull, W. A., Mendez, M. F., Ringman, J., Chui, H., Cotman, C., DeCarli, C., Miller, B. L., Geschwind, D. H. & Coppola, G., Apr 1 2015, In : JAMA Neurology. 72, 4, p. 414-422 9 p.

Research output: Contribution to journalArticle

Exome
Progressive Supranuclear Palsy
Frontotemporal Dementia
Alzheimer Disease
Genome
51 Citations (Scopus)

APOE effect on Alzheimer's disease biomarkers in older adults with significant memory concern

Risacher, S. L., Kim, S., Nho, K., Foroud, T., Shen, L., Petersen, R. C., Jack, C. R., Beckett, L. A., Aisen, P. S., Koeppe, R. A., Jagust, W. J., Shaw, L. M., Trojanowski, J. Q., Weiner, M. W., Saykin, A. & Alzheimer's Disease Neuroimaging Initiative (ADNI), D. N. I. ADNI., 2015, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Apolipoproteins E
Alzheimer Disease
Biomarkers
Apolipoprotein E4
Amyloid
16 Citations (Scopus)
Bipolar Disorder
National Institute of Mental Health (U.S.)
Depressive Disorder
Clinical Protocols
Area Under Curve
18 Citations (Scopus)

Association of long runs of homozygosity with Alzheimer disease among African American individuals

Ghani, M., Reitz, C., Cheng, R., Vardarajan, B. N., Jun, G., Sato, C., Naj, A., Rajbhandary, R., Wang, L. S., Valladares, O., Lin, C. F., Larson, E. B., Graff-Radford, N. R., Evans, D., De Jager, P. L., Crane, P. K., Buxbaum, J. D., Murrell, J. R., Raj, T., Ertekin-Taner, N. & 153 others, Logue, M., Baldwin, C. T., Green, R. C., Barnes, L. L., Cantwell, L. B., Fallin, M. D., Go, R. C. P., Griffith, P. A., Obisesan, T. O., Manly, J. J., Lunetta, K. L., Kamboh, M. I., Lopez, O. L., Bennett, D. A., Hendrie, H., Hall, K., Goate, A. M., Byrd, G. S., Kukull, W. A., Foroud, T., Haines, J. L., Farrer, L. A., Pericak-Vance, M. A., Lee, J. H., Schellenberg, G. D., St. George-Hyslop, P., Mayeux, R., Rogaeva, E., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Barber, R., Barmada, M. M., Beach, T. G., Beecham, G. W., Beekly, D., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cai, G., Cairns, N. J., Cao, C., Carlson, C. S., Carney, R. M., Carroll, S. L., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Cruchaga, C., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Dick, M., Faber, K. M., Fallon, K. B., Ferris, S., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Glass, J. D., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Hamilton-Nelson, K. L., Haroutunian, V., Harrell, L. E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Karydas, A., Kauwe, J. S. K., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., Kramer, P., LaFerla, F. M., Lah, J. J., Lang-Walker, R., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Olichney, J. M., Parisi, J. E., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Ringman, J. M., Roberson, E. D., Sano, M., Saykin, A., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E. & Yu, L., Nov 1 2015, In : JAMA Neurology. 72, 11, p. 1313-1323 11 p.

Research output: Contribution to journalArticle

African Americans
Alzheimer Disease
Single Nucleotide Polymorphism
Consensus
Dementia
27 Citations (Scopus)

Association of substance dependence phenotypes in the COGA sample

Wetherill, L., Agrawal, A., Kapoor, M., Bertelsen, S., Bierut, L. J., Brooks, A., Dick, D., Hesselbrock, M., Hesselbrock, V., Koller, D. L., Le, N., Nurnberger, J., Salvatore, J. E., Schuckit, M., Tischfield, J. A., Wang, J. C., Xuei, X., Edenberg, H., Porjesz, B., Bucholz, K. & 2 others, Goate, A. M. & Foroud, T., May 1 2015, In : Addiction Biology. 20, 3, p. 617-627 11 p.

Research output: Contribution to journalArticle

Substance-Related Disorders
Phenotype
Single Nucleotide Polymorphism
Diagnostic and Statistical Manual of Mental Disorders
Alcoholism
56 Citations (Scopus)

Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study

Alzheimer’s Disease Genetics Consortium, The GERAD1 Consortium & EPIC-InterAct Consortium, Jun 1 2015, In : PLoS Medicine. 12, 6, e1001841.

Research output: Contribution to journalArticle

Random Allocation
Alzheimer Disease
Smoking
Odds Ratio
Mendelian Randomization Analysis
12 Citations (Scopus)

Brief report: Genetics of alcoholic Cirrhosis-GenomALC multinational study

the GenomALC Consortium, May 1 2015, In : Alcoholism: Clinical and Experimental Research. 39, 5, p. 836-842 7 p.

Research output: Contribution to journalArticle

Alcoholic Liver Cirrhosis
Alcohols
Liver
Liver Diseases
Fathers
5 Citations (Scopus)

Characteristics of Bipolar I patients grouped by externalizing disorders

Swaminathan, S., Koller, D. L., Foroud, T., Edenberg, H., Xuei, X., Niculescu, A. & Nurnberger, J., Jul 1 2015, In : Journal of Affective Disorders. 178, p. 206-214 9 p., 7324.

Research output: Contribution to journalArticle

Mood Disorders
Calcium Channels
Bipolar Disorder
Genes
Single Nucleotide Polymorphism
107 Citations (Scopus)

Cognitive performance and neuropsychiatric symptoms in early, untreated Parkinson's disease

Parkinson's Progression Markers Initiative, Jun 1 2015, In : Movement Disorders. 30, 7, p. 919-927 9 p.

Research output: Contribution to journalArticle

Parkinson Disease
Disruptive, Impulse Control, and Conduct Disorders
Apathy
Aptitude
Psychotic Disorders
303 Citations (Scopus)

Common genetic variants influence human subcortical brain structures

Hibar, D. P., Stein, J. L., Renteria, M. E., Arias-Vasquez, A., Desrivières, S., Jahanshad, N., Toro, R., Wittfeld, K., Abramovic, L., Andersson, M., Aribisala, B. S., Armstrong, N. J., Bernard, M., Bohlken, M. M., Boks, M. P., Bralten, J., Brown, A. A., Mallar Chakravarty, M., Chen, Q., Ching, C. R. K. & 267 others, Cuellar-Partida, G., Den Braber, A., Giddaluru, S., Goldman, A. L., Grimm, O., Guadalupe, T., Hass, J., Woldehawariat, G., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Olde Loohuis, L. M., Luciano, M., MacAre, C., Mather, K. A., Mattheisen, M., Milaneschi, Y., Nho, K., Papmeyer, M., Ramasamy, A., Risacher, S. L., Roiz-Santiañez, R., Rose, E. J., Salami, A., Sämann, P. G., Schmaal, L., Schork, A. J., Shin, J., Strike, L. T., Teumer, A., Van Donkelaar, M. M. J., Van Eijk, K. R., Walters, R. K., Westlye, L. T., Whelan, C. D., Winkler, A. M., Zwiers, M. P., Alhusaini, S., Athanasiu, L., Ehrlich, S., Hakobjan, M. M. H., Hartberg, C. B., Haukvik, U. K., Heister, A. J. G. A. M., Hoehn, D., Kasperaviciute, D., Liewald, D. C. M., Lopez, L. M., Makkinje, R. R. R., Matarin, M., Naber, M. A. M., Reese McKay, D., Needham, M., Nugent, A. C., Pütz, B., Royle, N. A., Shen, L., Sprooten, E., Trabzuni, D., Van Der Marel, S. S. L., Van Hulzen, K. J. E., Walton, E., Wolf, C., Almasy, L., Ames, D., Arepalli, S., Assareh, A. A., Bastin, M. E., Brodaty, H., Bulayeva, K. B., Carless, M. A., Cichon, S., Corvin, A., Curran, J. E., Czisch, M., De Zubicaray, G. I., Dillman, A., Duggirala, R., Dyer, T. D., Erk, S., Fedko, I. O., Ferrucci, L., Foroud, T., Fox, P. T., Fukunaga, M., Raphael Gibbs, J., Göring, H. H. H., Green, R. C., Guelfi, S., Hansell, N. K., Hartman, C. A., Hegenscheid, K., Heinz, A., Hernandez, D. G., Heslenfeld, D. J., Hoekstra, P. J., Holsboer, F., Homuth, G., Hottenga, J. J., Ikeda, M., Jack, C. R., Jenkinson, M., Johnson, R., Kanai, R., Keil, M., Kent, J. W., Kochunov, P., Kwok, J. B., Lawrie, S. M., Liu, X., Longo, D. L., McMahon, K. L., Meisenzahl, E., Melle, I., Mohnke, S., Montgomery, G. W., Mostert, J. C., Mühleisen, T. W., Nalls, M. A., Nichols, T. E., Nilsson, L. G., Nöthen, M. M., Ohi, K., Olvera, R. L., Perez-Iglesias, R., Bruce Pike, G., Potkin, S. G., Reinvang, I., Reppermund, S., Rietschel, M., Romanczuk-Seiferth, N., Rosen, G. D., Rujescu, D., Schnell, K., Schofield, P. R., Smith, C., Steen, V. M., Sussmann, J. E., Thalamuthu, A., Toga, A. W., Traynor, B. J., Troncoso, J., Turner, J. A., Valdés Hernández, M. C., Van 'T Ent, D., Van Der Brug, M., Van Der Wee, N. J. A., Van Tol, M. J., Veltman, D. J., Wassink, T. H., Westman, E., Zielke, R. H., Zonderman, A. B., Ashbrook, D. G., Hager, R., Lu, L., McMahon, F. J., Morris, D. W., Williams, R. W., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Cahn, W., Calhoun, V. D., Cavalleri, G. L., Crespo-Facorro, B., Dale, A. M., Davies, G. E., Delanty, N., Depondt, C., Djurovic, S., Drevets, W. C., Espeseth, T., Gollub, R. L., Ho, B. C., Hoffmann, W., Hosten, N., Kahn, R. S., Le Hellard, S., Meyer-Lindenberg, A., Müller-Myhsok, B., Nauck, M., Nyberg, L., Pandolfo, M., Penninx, B. W. J. H., Roffman, J. L., Sisodiya, S. M., Smoller, J. W., Van Bokhoven, H., Van Haren, N. E. M., Völzke, H., Walter, H., Weiner, M. W., Wen, W., White, T., Agartz, I., Andreassen, O. A., Blangero, J., Boomsma, D. I., Brouwer, R. M., Cannon, D. M., Cookson, M. R., De Geus, E. J. C., Deary, I. J., Donohoe, G., Fernández, G., Fisher, S. E., Francks, C., Glahn, D. C., Grabe, H. J., Gruber, O., Hardy, J., Hashimoto, R., Hulshoff Pol, H. E., Jönsson, E. G., Kloszewska, I., Lovestone, S., Mattay, V. S., Mecocci, P., McDonald, C., McIntosh, A. M., Ophoff, R. A., Paus, T., Pausova, Z., Ryten, M., Sachdev, P. S., Saykin, A., Simmons, A., Singleton, A., Soininen, H., Wardlaw, J. M., Weale, M. E., Weinberger, D. R., Adams, H. H. H., Launer, L. J., Seiler, S., Schmidt, R., Chauhan, G., Satizabal, C. L., Becker, J. T., Yanek, L., Van Der Lee, S. J., Ebling, M., Fischl, B., Longstreth, W. T., Greve, D., Schmidt, H., Nyquist, P., Vinke, L. N., Van Duijn, C. M., Xue, L., Mazoyer, B., Bis, J. C., Gudnason, V., Seshadri, S., Ikram, M. A., Martin, N. G., Wright, M. J., Schumann, G., Franke, B., Thompson, P. M. & Medland, S. E., Apr 9 2015, In : Nature. 520, 7546, p. 224-229 6 p.

Research output: Contribution to journalArticle

Putamen
Brain
Developmental Genes
Transport Vesicles
Caudate Nucleus
16 Citations (Scopus)

Comprehensive gene- and pathway-based analysis of depressive symptoms in older adults

the Alzheimer's Disease Neuroimaging Initiative (ADNI) & Kim, S., 2015, In : Journal of Alzheimer's Disease. 45, 4, p. 1197-1206 10 p.

Research output: Contribution to journalArticle

Depression
Genes
Alzheimer Disease
Genome
Neuronal Plasticity
86 Citations (Scopus)

Convergent genetic and expression data implicate immunity in Alzheimer's disease

International Genomics of Alzheimer's Disease Consortium (IGAP), Jun 1 2015, In : Alzheimer's and Dementia. 11, 6, p. 658-671 14 p.

Research output: Contribution to journalArticle

Genomics
Endocytosis
Immunity
Alzheimer Disease
Cholesterol
12 Citations (Scopus)

FASTKD2 is associated with memory and hippocampal structure in older adults

Ramanan, V. K., Nho, K., Shen, L., Risacher, S. L., Kim, S., McDonald, B., Farlow, M., Foroud, T., Gao, S., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., Aisen, P. S., Petersen, R. C., Jack, C. R., Shaw, L. M., Trojanowski, J. Q. & 7 others, Weiner, M. W., Green, R. C., Toga, A. W., De Jager, P. L., Yu, L., Bennett, D. A. & Saykin, A., Oct 29 2015, In : Molecular Psychiatry. 20, 10, p. 1197-1204 8 p.

Research output: Contribution to journalArticle

Protein-Serine-Threonine Kinases
Memory Disorders
Neuroprotective Agents
Sirolimus
Genomics
91 Citations (Scopus)

Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE

Alzheimer's Disease Neuroimaging Initiative, May 19 2015, In : Nature Communications. 6, 6760.

Research output: Contribution to journalArticle

cerebrospinal fluid
Cerebrospinal fluid
Ferritins
Cerebrospinal Fluid
Alzheimer Disease
3 Citations (Scopus)

Fine mapping of bone structure and strength QTLs in heterogeneous stock rat

Alam, I., Koller, D. L., Cañete, T., Blázquez, G., Mont-Cardona, C., López-Aumatell, R., Martínez-Membrives, E., Díaz-Morán, S., Tobeña, A., Fernández-Teruel, A., Stridh, P., Diez, M., Olsson, T., Johannesson, M., Baud, A., Econs, M. & Foroud, T., Dec 1 2015, In : Bone. 81, p. 417-426 10 p., 10840.

Research output: Contribution to journalArticle

Quantitative Trait Loci
Femur Neck
Phenotype
Bone and Bones
Haplotypes
6 Citations (Scopus)

Genes associated with alcohol outcomes show enrichment of effects with broad externalizing and impulsivity phenotypes in an independent sample

Aliev, F., Wetherill, L., Bierut, L., Bucholz, K. K., Edenberg, H., Foroud, T., Investigators, C. & Xuei, X., Jan 1 2015, In : Journal of Studies on Alcohol and Drugs. 76, 1, p. 38-46 9 p.

Research output: Contribution to journalArticle

Impulsive Behavior
Genes
Polymorphism
alcohol
Alcohols
17 Citations (Scopus)

Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses

Adult Changes in Thought Study Investigators, Religious Orders Study/Memory and Aging Project Investigators & Alzheimer's Disease Genetics Consortium, Dec 1 2015, In : Alzheimer's and Dementia. 11, 12, p. 1439-1451 13 p.

Research output: Contribution to journalArticle

Mendelian Randomization Analysis
Alzheimer Disease
Body Mass Index
Phenotype
Odds Ratio
5 Citations (Scopus)

Genetic influences on plasma homocysteine levels in African Americans and Yoruba Nigerians

Kim, S., Nho, K., Ramanan, V. K., Lai, D., Foroud, T., Lane, K., Murrell, J. R., Gao, S., Hall, K., Unverzagt, F., Baiyewu, O., Ogunniyi, A., Gureje, O., Kling, M. A., Doraiswamy, P. M., Kaddurah-Daouk, R., Hendrie, H. & Saykin, A., Dec 24 2015, In : Journal of Alzheimer's Disease. 49, 4, p. 991-1003 13 p.

Research output: Contribution to journalArticle

Homocysteine
African Americans
GABA Receptors
Dementia
Alzheimer Disease
1331 Citations (Scopus)

Genetic studies of body mass index yield new insights for obesity biology

Collaborators, LifeLines Cohort Study & ADIPOGen Consortium; AGEN-BMI Working Group; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GLGC; ICBP; MAGIC Investigators; MuTHER Consortium; MIGen Consortium; PAGE Consortium; ReproGen Consortium; GENIE Consortium; International Endogene Consortium, Feb 12 2015, In : Nature. 518, 7538, p. 197-206 10 p.

Research output: Contribution to journalArticle

Body Mass Index
Obesity
Adipogenesis
Genome-Wide Association Study
Adiposity
71 Citations (Scopus)

Genetic studies of quantitative MCI and AD phenotypes in ADNI: Progress, opportunities, and plans

Saykin, A., Shen, L., Yao, X., Kim, S., Nho, K., Risacher, S. L., Ramanan, V. K., Foroud, T., Faber, K. M., Sarwar, N., Munsie, L. M., Hu, X., Soares, H. D., Potkin, S. G., Thompson, P. M., Kauwe, J. S. K., Kaddurah-Daouk, R., Green, R. C., Toga, A. W. & Weiner, M. W., Jul 1 2015, In : Alzheimer's and Dementia. 11, 7, p. 792-814 23 p.

Research output: Contribution to journalArticle

Neuroimaging
Alzheimer Disease
Phenotype
Genome-Wide Association Study
Exome
5 Citations (Scopus)

Genetic variants associated with susceptibility to psychosis in late-onset Alzheimer's disease families

NIA-LOAD/NCRAD Family Study Group, Nov 1 2015, In : Neurobiology of Aging. 36, 11, p. 3116.e9-3116.e16

Research output: Contribution to journalArticle

Psychotic Disorders
Alzheimer Disease
Hispanic Americans
Brain
Genes
13 Citations (Scopus)

Genome-wide association data suggest ABCB1 and immune-related gene sets may be involved in adult antisocial behavior

Salvatore, J. E., Edwards, A. C., McClintick, J., Bigdeli, T. B., Adkins, A., Aliev, F., Edenberg, H., Foroud, T., Hesselbrock, V., Kramer, J., Nurnberger, J., Schuckit, M., Tischfield, J. A., Xuei, X. & Dick, D. M., Apr 28 2015, In : Translational Psychiatry. 5, 4, e558.

Research output: Contribution to journalArticle

Genome
Diagnostic and Statistical Manual of Mental Disorders
Genes
Alcoholism
Single Nucleotide Polymorphism
48 Citations (Scopus)

Genome-Wide Association Studies for Taxane-Induced Peripheral Neuropathy in ECOG-5103 and ECOG-1199

Schneider, B., Li, L., Radovich, M., Shen, F., Miller, K., Flockhart, D. A., Jiang, G., Vance, G., Gardner, L., Vatta, M., Bai, S., Lai, D., Koller, D., Zhao, F., O'Neill, A., Smith, M. L., Railey, E., White, C., Partridge, A., Sparano, J. & 3 others, Davidson, N. E., Foroud, T. & Sledge, G. W., Nov 15 2015, In : Clinical Cancer Research. 21, 22, p. 5082-5091 10 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Peripheral Nervous System Diseases
Single Nucleotide Polymorphism
taxane
Breast Neoplasms
47 Citations (Scopus)

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

Hou, L., Bergen, S. E., Akula, N., Song, J., Hultman, C. M., Landén, M., Adli, M., Alda, M., Ardau, R., Arias, B., Aubry, J. M., Backlund, L., Badner, J. A., Barrett, T. B., Bauer, M., Baune, B. T., Bellivier, F., Benabarre, A., Bengesser, S., Berrettini, W. H. & 119 others, Bhattacharjee, A. K., Biernacka, J. M., Birner, A., Bloss, C. S., Brichant-Petitjean, C., Bui, E. T., Byerley, W., Cervantes, P., Chillotti, C., Cichon, S., Colom, F., Coryell, W., Craig, D. W., Cruceanu, C., Czerski, P. M., Davis, T., Dayer, A., Degenhardt, F., Del Zompo, M., DePaulo, J. R., Edenberg, H., Étain, B., Falkai, P., Foroud, T., Forstner, A. J., Frisén, L., Frye, M. A., Fullerton, J. M., Gard, S., Garnham, J. S., Gershon, E. S., Goes, F. S., Greenwood, T. A., Grigoroiu-Serbanescu, M., Hauser, J., Heilbronner, U., Heilmann-Heimbach, S., Herms, S., Hipolito, M., Hitturlingappa, S., Hoffmann, P., Hofmann, A., Jamain, S., Jiménez, E., Kahn, J. P., Kassem, L., Kelsoe, J. R., Kittel-Schneider, S., Kliwicki, S., Koller, D. L., König, B., Lackner, N., Laje, G., Lang, M., Lavebratt, C., Lawson, W. B., Leboyer, M., Leckband, S. G., Liu, C., Maaser, A., Mahon, P. B., Maier, W., Maj, M., Manchia, M., Martinsson, L., McCarthy, M. J., McElroy, S. L., McInnis, M. G., McKinney, R., Mitchell, P. B., Mitjans, M., Mondimore, F. M., Monteleone, P., Mühleisen, T. W., Nievergelt, C. M., Nöthen, M. M., Novák, T., Nurnberger, J., Nwulia, E. A., Ösby, U., Pfennig, A., Potash, J. B., Propping, P., Reif, A., Reininghaus, E., Rice, J., Rietschel, M., Rouleau, G. A., Rybakowski, J. K., Schalling, M., Scheftner, W. A., Schofield, P. R., Schork, N. J., Schulze, T. G., Schumacher, J., Schweizer, B. W., Severino, G., Shekhtman, T., Shilling, P. D., Simhandl, C., Slaney, C. M., Smith, E. N., Squassina, A., Stamm, T., Stopkova, P., Streit, F., Strohmaier, J., Szelinger, S., Tighe, S. K., Tortorella, A., Turecki, G., Vieta, E., Volkert, J., Witt, S. H., Wright, A., Zandi, P. P., Zhang, P., Zollner, S. & McMahon, F. J., 2015, In : Human Molecular Genetics. 25, 15, p. 3383-3394 12 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Bipolar Disorder
X Chromosome
Lithium
Odds Ratio
8 Citations (Scopus)

Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk

Hohman, T. J., Cooke-Bailey, J. N., Reitz, C., Jun, G., Naj, A., Beecham, G. W., Liu, Z., Carney, R. M., Vance, J. M., Cuccaro, M. L., Rajbhandary, R., Vardarajan, B. N., Wang, L. S., Valladares, O., Lin, C. F., Larson, E. B., Graff-Radford, N. R., Evans, D., De Jager, P. L., Crane, P. K. & 33 others, Buxbaum, J. D., Murrell, J. R., Raj, T., Ertekin-Taner, N., Logue, M. W., Baldwin, C. T., Green, R. C., Barnes, L. L., Cantwell, L. B., Fallin, M. D., Go, R. C. P., Griffith, P., Obisesan, T. O., Manly, J. J., Lunetta, K. L., Kamboh, M. I., Lopez, O. L., Bennett, D. A., Hardy, J., Hendrie, H., Hall, K., Goate, A. M., Lang, R., Byrd, G. S., Kukull, W. A., Foroud, T., Farrer, L. A., Martin, E. R., Pericak-Vance, M. A., Schellenberg, G. D., Mayeux, R., Haines, J. L. & Thornton-Wells, T. A., 2015, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

African Americans
Alzheimer Disease
Genome-Wide Association Study
83 Citations (Scopus)

Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research

O'Bryant, S. E., Gupta, V., Henriksen, K., Edwards, M., Jeromin, A., Lista, S., Bazenet, C., Soares, H., Lovestone, S., Hampel, H., Montine, T., Blennow, K., Foroud, T., Carrillo, M., Graff-Radford, N., Laske, C., Breteler, M., Shaw, L., Trojanowski, J. Q., Schupf, N. & 8 others, Rissman, R. A., Fagan, A. M., Oberoi, P., Umek, R., Weiner, M. W., Grammas, P., Posner, H. & Martins, R., May 1 2015, In : Alzheimer's and Dementia. 11, 5, p. 549-560 12 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Biomarkers
Guidelines
Research
Neuroimaging
41 Citations (Scopus)

GWAS of longitudinal amyloid accumulation on 18F-florbetapir PET in Alzheimer's disease implicates microglial activation gene IL1RAP

Ramanan, V. K., Risacher, S. L., Nho, K., Kim, S., Shen, L., McDonald, B., Yoder, K., Hutchins, G., West, J. D., Tallman, E. F., Gao, S., Foroud, T., Farlow, M., De Jager, P. L., Bennett, D. A., Aisen, P. S., Petersen, R. C., Jack, C. R., Toga, A. W., Green, R. C. & 3 others, Jagust, W. J., Weiner, M. W. & Saykin, A., Oct 1 2015, In : Brain. 138, 10, p. 3076-3088 13 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Amyloid
Transcriptional Activation
Alzheimer Disease
Interleukin-1 Receptor Accessory Protein
32 Citations (Scopus)

Integrating mRNA and miRNA weighted gene co-expression networks with eQTLs in the nucleus accumbens of subjects with alcohol dependence

Mamdani, M., Williamson, V., McMichael, G. O., Blevins, T., Aliev, F., Adkins, A., Hack, L., Bigdeli, T., Van Der Vaart, A. D., Web, B. T., Bacanu, S. A., Kalsi, G., Kendler, K. S., Miles, M. F., Dick, D., Riley, B. P., Dumur, C., Vladimirov, V. I., Hesselbrock, V., Edenberg, H. & 29 others, Nurnberger, J., Foroud, T., Kuperman, S., Kramer, J., Porjesz, B., Bierut, L., Goate, A., Rice, J., Bucholz, K., Schuckit, M., Tischfield, J., Almasy, L., Taylor, R., Dick, D., Bauer, L., Koller, D., O'Connor, S., Wetherill, L., Xuei, X., Chan, G., Kang, S., Manz, N., Rangaswamy, M., Rohrbaugh, J., Wang, J. C., Brooks, A., Aliev, F., Parsian, A. & Reilly, M., Sep 18 2015, In : PLoS One. 10, 9, e0137671.

Research output: Contribution to journalArticle

Nucleus Accumbens
alcohol abuse
MicroRNAs
microRNA
Alcoholism
96 Citations (Scopus)

Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder

Cross-Disorder Working Group of the Psychiatric Genomics Consortium, Feb 5 2015, In : American Journal of Human Genetics. 96, 2, p. 283-294 12 p.

Research output: Contribution to journalArticle

Major Depressive Disorder
Bipolar Disorder
Psychiatry
Schizophrenia
Sample Size
20 Citations (Scopus)

Large-scale genomics unveil polygenic architecture of human cortical surface area

Chen, C. H., Peng, Q., Schork, A. J., Lo, M. T., Fan, C. C., Wang, Y., Desikan, R. S., Bettella, F., Hagler, D. J., Westlye, L. T., Kremen, W. S., Jernigan, T. L., Le Hellard, S., Steen, V. M., Espeseth, T., Huentelman, M., Håberg, A. K., Agartz, I., Djurovic, S., Andreassen, O. A. & 86 others, Schork, N., Dale, A. M., McCabe, C., Chang, L., Akshoomoff, N., Newman, E., Ernst, T., Van Zijl, P., Kuperman, J., Murray, S., Bloss, C., Appelbaum, M., Gamst, A., Thompson, W., Bartsch, H., Weiner, M., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A., Morris, J., Shaw, L. M., Khachaturian, Z., Sorensen, G., Carrillo, M., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulman, M. M., Potter, W., Snyder, P. J., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., DeCarli, C., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Landau, S., Cairns, N. J., Householder, E., Taylor-Reinwald, L., Lee, V. M. Y., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T., Potkin, S., Shen, L., Faber, K., Kim, S., Nho, K., Thal, L., Frank, R., Buckholtz, N., Albert, M. & Hsiao, J., Jul 20 2015, In : Nature Communications. 6, 7549.

Research output: Contribution to journalArticle

polymorphism
nucleotides
Genomics
Polymorphism
Single Nucleotide Polymorphism
15 Citations (Scopus)

Lessons learned from whole exome sequencing in multiplex families affected by a complex genetic disorder, intracranial aneurysm

Farlow, J. L., Lin, H., Sauerbeck, L., Lai, D., Koller, D. L., Pugh, E., Hetrick, K., Ling, H., Kleinloog, R., Van Der Vlies, P., Deelen, P., Swertz, M. A., Verweij, B. H., Regli, L., Rinkel, G. J. E., Ruigrok, Y. M., Doheny, K., Liu, Y., Foroud, T., Broderick, J. & 59 others, Woo, D., Kissela, B., Kleindorfer, D., Schneider, A., Zuccarello, M., Ringer, A., Deka, R., Brown, R. D., Huston, J., Mesissner, I., Wiebers, D., Qureshi, A. I., Rasmussen, P. A., Connolly, E. S., Sacco, R. L., Malkaff, M., Payner, T. D., Ferguson, G. G., Aldrich, E. F., Rouleau, G., Anderson, C. S., Mee, E. W., Hankey, G. J., Knuckey, N., Reilly, P. L., Laidlaw, J. D., D'Urso, P., Rosenfeld, J. V., Morgan, M. K., Dorsch, N., Besser, M., Batjer, H. H., Richard, M. T., Kassam, A., Steinberg, G. K., Johnston, S. C., Ko, N. U., Giannotta, S. L., Kassell, N. F., Worrall, B. B., Lui, K. C., Dumont, A., Tirschell, D. L., Kaufmann, A. M., Fisher, W. S., Aziz, K. M. A., Day, A. L., Du, R., Ogilvy, C., Lewis, S. B., Murphy, K. P., Radvany, M., Gandhi, D., Lisabeth, L., Pandey, A., Morgenstern, L., Derdeyn, C., Langefeld, C. & Bailey-Wilson, J., Mar 24 2015, In : PLoS One. 10, 3, e0121104.

Research output: Contribution to journalArticle

Exome
aneurysm
Inborn Genetic Diseases
Intracranial Aneurysm
genetic disorders
12 Citations (Scopus)

Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease

Barral, S., Cheng, R., Reitz, C., Vardarajan, B., Lee, J., Kunkle, B., Beecham, G., Cantwell, L. S., Pericak-Vance, M. A., Farrer, L. A., Haines, J. L., Goate, A. M., Foroud, T., Boerwinkle, E., Schellenberg, G. D. & Mayeux, R., Dec 1 2015, In : Alzheimer's and Dementia. 11, 12, p. 1397-1406 10 p.

Research output: Contribution to journalArticle

Hispanic Americans
Alzheimer Disease
Multigene Family
Nervous System
Joints
472 Citations (Scopus)

New genetic loci link adipose and insulin biology to body fat distribution

Collaborators & ADIPOGen Consortium; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GEFOS Consortium; GENIE Consortium; GLGC; ICBP; International Endogene Consortium; LifeLines Cohort Study; MAGIC Investigators; MuTHER Consortium; PAGE Consortium; ReproGen Consortium, Feb 12 2015, In : Nature. 518, 7538, p. 187-196 10 p.

Research output: Contribution to journalArticle

Body Fat Distribution
Genetic Loci
Waist-Hip Ratio
Waist Circumference
Hip
4 Citations (Scopus)

Novel recruitment strategy to enrich for lrrk2 mutation carriers

Foroud, T., Smith, D., Jackson, J., Verbrugge, J., Halter, C., Wetherill, L., Sims, K., Xin, W., Arnedo, V., Lasch, S. & Marek, K., Jan 1 2015, In : Molecular Genetics and Genomic Medicine. 3, 5, p. 404-412 9 p.

Research output: Contribution to journalArticle

Open Access
Mutation
Parkinson Disease
Internet
Biomarkers
Clinical Trials
26 Citations (Scopus)

PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease

Beecham, G. W., Dickson, D. W., Scott, W. K., Martin, E. R., Schellenberg, G., Nuytemans, K., Larson, E. B., Buxbaum, J. D., Trojanowski, J. Q., Van Deerlin, V. M., Hurtig, H. I., Mash, D. C., Beach, T. G., Troncoso, J. C., Pletnikova, O., Frosch, M. P., Ghetti, B., Foroud, T., Honig, L. S., Marder, K. & 12 others, Vonsattel, J. P., Goldman, S. M., Vinters, H. V., Ross, O. A., Wszolek, Z. K., Wang, L., Dykxhoorn, D. M., Pericak-Vance, M. A., Montine, T. J., Leverenz, J. B., Dawson, T. M. & Vance, J. M., Mar 10 2015, In : Neurology. 84, 10, p. 972-980 9 p.

Research output: Contribution to journalArticle

Parkinson Disease
Genome-Wide Association Study
Haplotypes
Genetic Heterogeneity
Chromosomes, Human, Pair 1
45 Citations (Scopus)

Peroxisome Proliferator-Activated Receptors α and γ are Linked with Alcohol Consumption in Mice and Withdrawal and Dependence in Humans

Blednov, Y. A., Benavidez, J. M., Black, M., Ferguson, L. B., Schoenhard, G. L., Goate, A. M., Edenberg, H., Wetherill, L., Hesselbrock, V., Foroud, T. & Adron Harris, R., Jan 1 2015, In : Alcoholism: Clinical and Experimental Research. 39, 1, p. 136-145 10 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Alcohol Drinking
Alcohols
Alcoholism
Association reactions
35 Citations (Scopus)

Polygenic Risk for Externalizing Disorders: Gene-by-Development and Gene-by-Environment Effects in Adolescents and Young Adults

Salvatore, J. E., Aliev, F., Bucholz, K., Agrawal, A., Hesselbrock, V., Hesselbrock, M., Bauer, L., Kuperman, S., Schuckit, M. A., Kramer, J. R., Edenberg, H., Foroud, T. & Dick, D. M., Mar 1 2015, In : Clinical Psychological Science. 3, 2, p. 189-201 13 p.

Research output: Contribution to journalArticle

Young Adult
Impulsive Behavior
Genes
Psychopathology
Genome-Wide Association Study
31 Citations (Scopus)

Protective variant for hippocampal atrophy identified by whole exome sequencing

Nho, K., Kim, S., Risacher, S. L., Shen, L., Corneveaux, J. J., Swaminathan, S., Lin, H., Ramanan, V. K., Liu, Y., Foroud, T., Inlow, M. H., Siniard, A. L., Reiman, R. A., Aisen, P. S., Petersen, R. C., Green, R. C., Jack, C. R., Weiner, M. W., Baldwin, C. T., Lunetta, K. L. & 14 others, Farrer, L. A., Furney, S. J., Lovestone, S., Simmons, A., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., McDonald, B., Farlow, M., Ghetti, B., Huentelman, M. J. & Saykin, A., Mar 1 2015, In : Annals of Neurology. 77, 3, p. 547-552 6 p.

Research output: Contribution to journalArticle

Exome
Neurogenesis
Neuroimaging
Computer Simulation
Atrophy