Thomas Gardner

  • 3459 Citations
  • 31 h-Index
1977 …2020

Research output per year

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Publications

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[11C]Choline as a PET biomarker for assessment of prostate cancer tumor models

Zheng, Q. H., Gardner, T. A., Raikwar, S., Kao, C., Stone, K. L., Martinez, T. D., Mock, B. H., Fei, X., Wang, J. Q. & Hutchins, G. D., Jun 1 2004, In : Bioorganic and Medicinal Chemistry. 12, 11, p. 2887-2893 7 p.

Research output: Contribution to journalArticle

53 Scopus citations

Aberrant expression of CARM1, a transcriptional coactivator of androgen receptor, in the development of prostate carcinoma and androgen-independent status

Hong, H., Kao, C., Jeng, M. H., Eble, J. N., Koch, M. O., Gardner, T. A., Zhang, S., Li, L., Pan, C. X., Hu, Z., MacLennan, G. T. & Cheng, L., Jul 1 2004, In : Cancer. 101, 1, p. 83-89 7 p.

Research output: Contribution to journalArticle

136 Scopus citations
20 Scopus citations

A conditionally replicative, Wnt/Β-catenin pathway-based adenovirus therapy for anaplastic thyroid cancer

Abbosh, P. H., Li, X., Li, L., Gardner, T. A., Kao, C. & Nephew, K. P., Apr 1 2007, In : Cancer gene therapy. 14, 4, p. 399-408 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

A conditional replication-competent adenoviral vector, AD-OC-E1a, to cotarget prostate cancer and bone stroma in an experimental model of androgen-independent prostate cancer bone metastasis

Matsubara, S., Wada, Y., Gardner, T. A., Egawa, M., Par, M. S., Hsieh, C. L., Zhau, H. E., Kao, C., Kamidono, S., Gillenwater, J. Y. & Chung, L. W. K., Aug 15 2001, In : Cancer Research. 61, 16, p. 6012-6019 8 p.

Research output: Contribution to journalArticle

134 Scopus citations

Adenoviral vectors expressing human endostatin-angiostatin and soluble Tie2: Enhanced suppression of tumor growth and antiangiogenic effects in a prostate tumor model

Raikwar, S. P., Temm, C. J., Raikwar, N. S., Kao, C., Molitoris, B. A. & Gardner, T. A., Dec 2005, In : Molecular Therapy. 12, 6, p. 1091-1100 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

Adenovirus-mediated suicide-gene therapy in an orthotopic murine bladder tumor model

Cheon, J., Moon, D. G., Cho, H. Y., Park, H. S., Kim, J. J., Gardner, T. A. & Kao, C., Jun 26 2002, In : International Journal of Urology. 9, 5, p. 261-267 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Allelic Loss of the Active X Chromosome during Bladder Carcinogenesis

Cheng, L., MacLennan, G. T., Pan, C. X., Jones, T. D., Moore, C. R., Zhang, S., Gu, J., Patel, N. B., Kao, C. & Gardner, T. A., Feb 1 2004, In : Archives of Pathology and Laboratory Medicine. 128, 2, p. 187-190 4 p.

Research output: Contribution to journalArticle

25 Scopus citations
39 Scopus citations
33 Scopus citations

An Improved Total Synthesis of PET HSV-tk Gene Expression Imaging Agent 9-[(3-[18F]Fluoro-1-hydroxy-2-propoxy)methyl]guanine ([ 18F]FHPG)

Wang, J. Q., Zheng, Q. H., Fei, X., Liu, X., Gardner, T. A., Kao, C., Raikwar, S. P., Glick-Wilson, B. E., Sullivan, M. L., Mock, B. H. & Hutchins, G. D., Mar 31 2004, In : Synthetic Communications. 34, 5, p. 917-932 16 p.

Research output: Contribution to journalArticle

9 Scopus citations

An Improved Total Synthesis of PET HSV-tk Gene Reporter Probe 9-(4-[ 18F]Fluoro-3-hydroxymethylbutyl)guanine ([18F]FHBG)

Zheng, Q. H., Wang, J. Q., Liu, X., Fei, X., Mock, B. H., Glick-Wilson, B. E., Sullivan, M. L., Raikwar, S. P., Gardner, T. A., Kao, C. & Hutchins, G. D., Mar 26 2004, In : Synthetic Communications. 34, 4, p. 689-704 16 p.

Research output: Contribution to journalArticle

10 Scopus citations

Anti-angiogenic gene therapy for metastatic renal cell carcinoma produces tumor growth suppression in an athymic nude mouse model

Mellon, M. J., Ahn, M., Jiménez, J. A., Kao, C. & Gardner, T. A., Feb 2008, In : Journal of Urology. 179, 2, p. 737-742 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Antitumor activity of Ad-IU2, a prostate-specific replication-competent adenovirus encoding the apoptosis inducer, TRAIL

Jiménez, J. A., Li, X., Zhang, Y. P., Bae, K. H., Mohammadi, Y., Pandya, P., Kao, C. & Gardner, T. A., Mar 1 2010, In : Cancer gene therapy. 17, 3, p. 180-191 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Anti-tumor efficacy of a transcriptional replication-competent adenovirus, Ad-OC-E1a, for osteosarcoma pulmonary metastasis

Li, X., Jung, C., Liu, Y. H., Bae, K. H., Zhang, Y. P., Zhang, H. J., VanderPutten, D., Jeng, M. H., Gardner, T. A. & Kao, C., Jun 1 2006, In : Journal of Gene Medicine. 8, 6, p. 679-689 11 p.

Research output: Contribution to journalArticle

17 Scopus citations
10 Scopus citations

A phase II trial of dovitinib in BCG-unresponsive urothelial carcinoma with FGFR3 mutations or overexpression: Hoosier Cancer Research Network trial HCRN 12-157

Hahn, N. M., Bivalacqua, T. J., Ross, A. E., Netto, G. J., Baras, A., Park, J. C., Chapman, C., Masterson, T. A., Koch, M. O., Bihrle, R., Foster, R. S., Gardner, T. A., Cheng, L., Jones, D. R., McElyea, K., Sandusky, G. E., Breen, T., Liu, Z., Albany, C., Moore, M. L. & 9 others, Loman, R. L., Reed, A., Turner, S. A., De Abreu, F. B., Gallagher, T., Tsongalis, G. J., Plimack, E. R., Greenberg, R. E. & Geynisman, D. M., Jun 15 2017, In : Clinical Cancer Research. 23, 12, p. 3003-3011 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

A potential for tissue restrictive gene therapy in renal cell carcinoma using MN/CA IX promoter

Ou, Y. C., Gardner, T. A., Kao, C., Zhau, H. E. & Chung, L. W., Mar 1 2005, In : Anticancer Research. 25, 2 A, p. 881-886 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

A randomized phase II trial of sipuleucel-T with concurrent versus sequential abiraterone acetate plus prednisone in metastatic castration-resistant prostate cancer

Small, E. J., Lance, R. S., Gardner, T. A., Karsh, L. I., Fong, L., McCoy, C., De Vries, T., Sheikh, N. A., GuhaThakurta, D., Chang, N., Redfern, C. H. & Shore, N. D., Sep 1 2015, In : Clinical Cancer Research. 21, 17, p. 3862-3869 8 p.

Research output: Contribution to journalArticle

44 Scopus citations

Assessing Cost of Robotic Utilization in Partial Nephrectomy with Increasing Utilization

Bahler, C., Monn, M. F., Flack, C. K., Gramm, A. R., Gardner, T. & Sundaram, C., Aug 1 2018, In : Journal of Endourology. 32, 8, p. 710-716 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

A transient increase in eosinophils is associated with prolonged survival in men with metastatic castration-resistant prostate cancer who receive sipuleucel-T

McNeel, D. G., Gardner, T. A., Higano, C. S., Kantoff, P. W., Small, E. J., Wener, M. H., Sims, R. B., DeVries, T., Sheikh, N. A. & Dreicer, R., Oct 1 2014, In : Cancer Immunology Research. 2, 10, p. 988-999 12 p.

Research output: Contribution to journalArticle

25 Scopus citations
23 Scopus citations

Biology of Childhood Osteogenic Sarcoma and Potential Targets for Therapeutic Development: Meeting Summary

Gorlick, R., Anderson, P., Andrulis, I., Arndt, C., Beardsley, G. P., Bernstein, M., Bridge, J., Cheung, N. K., Dome, J. S., Ebb, D., Gardner, T., Gebhardt, M., Grier, H., Hansen, M., Healey, J., Helman, L., Hock, J., Houghton, J., Houghton, P., Huvos, A. & 19 others, Khanna, C., Kieran, M., Kleinerman, E., Ladanyi, M., Lau, C., Malkin, D., Marina, N., Meltzer, P., Meyers, P., Schofield, D., Schwartz, C., Smith, M. A., Toretsky, J., Tsokos, M., Wexler, L., Wigginton, J., Withrow, S., Schoenfeldt, M. & Anderson, B., Nov 15 2003, In : Clinical Cancer Research. 9, 15, p. 5442-5453 12 p.

Research output: Contribution to journalArticle

141 Scopus citations

Chemogene therapy: Osteocalcin promoter-based suicide gene therapy in combination with methotrexate in a marine osteosarcoma model

Cheon, J., Ko, S. C., Gardner, T. A., Shirakawa, T., Gotoh, A., Kao, C. & Chung, L. W. K., Dec 1 1997, In : Cancer gene therapy. 4, 6, p. 359-365 7 p.

Research output: Contribution to journalArticle

54 Scopus citations

Combination therapy of androgen-independent prostate cancer using a prostate restricted replicative adenovirus and a replication-defective adenovirus encoding human endostatin-angiostatin fusion gene

Li, X., Raikwar, S. P., Liu, Y. H., Lee, S. J., Zhang, Y. P., Zhang, S., Cheng, L., Lee, S. D., Juliar, B. E., Gardner, T. A., Jeng, M. H. & Kao, C., Mar 1 2006, In : Molecular cancer therapeutics. 5, 3, p. 676-684 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Comparison of laparoscopic pyeloplasty with and without robotic assistance.

Bernie, J. E., Venkatesh, R., Brown, J., Gardner, T. A. & Sundaram, C. P., Jan 1 2005, In : JSLS : Journal of the Society of Laparoendoscopic Surgeons / Society of Laparoendoscopic Surgeons. 9, 3, p. 258-261 4 p.

Research output: Contribution to journalArticle

37 Scopus citations

Comparison of robot-assisted nephrectomy with laparoscopic and hand-assisted laparoscopic nephrectomy

Boger, M., Lucas, S. M., Popp, S. C., Gardner, T. A. & Sundaram, C. P., Jul 1 2010, In : Journal of the Society of Laparoendoscopic Surgeons. 14, 3, p. 374-380 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Concurrent malakoplakia and primary squamous cell carcinoma arising in long‐standing chronic cystitis

NGADIMAN, S., HODA, S. A., CAMPBELL, W. G., GARDNER, T. & MAY, M., Dec 1994, In : British Journal of Urology. 74, 6, p. 801-802 2 p.

Research output: Contribution to journalArticle

5 Scopus citations

Conversions in laparoscopic renal surgery: Causes and outcomes

Ivey, B. S., Lucas, S. M., Meyer, C. A., Emley, T. E., Bey, A., Gardner, T. A. & Sundaram, C. P., Jul 1 2011, In : Journal of Endourology. 25, 7, p. 1167-1173 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Cotargeting tumor and stroma in a novel chimeric tumor model involving the growth of both human prostate cancer and bone stromal cells

Hsieh, C. L., Gardner, T. A., Miao, L., Balian, G. & Chung, L. W. K., Feb 1 2004, In : Cancer Gene Therapy. 11, 2, p. 148-155 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

Cytotoxicity of adenoviral-mediated cytosine deaminase plus 5- fluorocytosine gene therapy is superior to thymidine kinase plus acyclovir in a human renal cell carcinoma model

Shirakawa, T., Gardner, T. A., Ko, S. C., Bander, N., Woo, S., Gotoh, A., Kamidono, S., Chung, L. W. K. & Kao, C., Sep 1999, In : Journal of Urology. 162, 3 I, p. 949-954 6 p.

Research output: Contribution to journalArticle

31 Scopus citations

Development of human chorionic gonadotropin subunit-beta promoter-based toxic gene therapy for testicular cancer.

Shirakawa, T., Gotoh, A., Zhang, Z., Kao, C., Chung, L. W. K. & Gardner, T. A., Mar 2004, In : Urology. 63, 3, p. 613-618 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Development of prostate-specific antigen promoter-based gene therapy for androgen-independent human prostate cancer

Gotoh, A., Ko, S. C., Shirakawa, T., Cheon, J., Kao, C., Miyamoto, T., Gardner, T. A., Ho, L. J., Cleutjens, C. B. J., Trapman, J., Graham, F. L. & Chung, L. W. K., Jul 1998, In : Journal of Urology. 160, 1, p. 220-229 10 p.

Research output: Contribution to journalArticle

101 Scopus citations

Diagnostic flexible peritoneoscopy: Assessment of the contralateral internal inguinal ring during unilateral herniorrhaphy

Gardner, T. A., Ostad, M. & Mininberg, D. T., Oct 1998, In : Journal of Pediatric Surgery. 33, 10, p. 1486-1489 4 p.

Research output: Contribution to journalArticle

11 Scopus citations

Differential expression of osteocalcin during the metastatic progression of prostate cancer

Gardner, T. A., Lee, S. J., Lee, S. D., Li, X., Shirakawa, T., Kwon, D. D., Park, R. Y., Ahn, K. Y. & Jung, C., Jun 29 2009, In : Oncology reports. 21, 4, p. 903-908 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Drug-resistant human bladder-cancer cells are more sensitive to adenovirus-mediated wild-type p53 gene therapy compared to drug-sensitive cells

Shirakawa, T., Sasaki, R., Gardner, T. A., Kao, C., Zhang, Z. J., Sugimura, K., Matsuo, M., Kamidono, S. & Gotoh, A., Oct 15 2001, In : International Journal of Cancer. 94, 2, p. 282-289 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Early catheter removal after radical retropubic prostatectomy: Long-term followup

Koch, M. O., Nayee, A. H., Sloan, J., Gardner, T., Wahle, G. R., Bihrle, R. & Foster, R. S., Jun 1 2003, In : Journal of Urology. 169, 6, p. 2170-2172 3 p.

Research output: Contribution to journalArticle

46 Scopus citations

Elevated activated partial thromboplastin time during administration of first-generation adenoviral vectors for gene therapy for prostate cancer: Identification of lupus anticoagulants

Malaeb, B. S., Gardner, T. A., Margulis, V., Yang, L., Gillenwater, J. Y., Chung, L. W. K., Macik, G. & Koeneman, K. S., Oct 1 2005, In : Urology. 66, 4, p. 830-834 5 p.

Research output: Contribution to journalArticle

11 Scopus citations

Enhanced combined tumor-specific oncolysis and suicide gene therapy for prostate cancer using M6 promoter

Ahn, M., Lee, S. J., Li, X., Jiménez, J. A., Zhang, Y. P., Bae, K. H., Mohammadi, Y., Kao, C. & Gardner, T. A., Jan 1 2009, In : Cancer gene therapy. 16, 1, p. 73-82 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Estimation of radiation dosimetry for 68Ga-HBED-CC (PSMA-11) in patients with suspected recurrence of prostate cancer

Green, M. A., Eitel, J. A., Fletcher, J. W., Mathias, C. J., Tann, M. A., Territo, W., Polson, H., Hutchins, G. D., Gardner, T. & Koch, M. O., Mar 1 2017, In : Nuclear Medicine and Biology. 46, p. 32-35 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Evaluation of hydrogel tissue sealant in porcine laparoscopic partial-nephrectomy model

Bernie, J. E., Ng, J., Bargman, V., Gardner, T., Cheng, L. & Sundaram, C. P., Nov 1 2005, In : Journal of Endourology. 19, 9, p. 1122-1126 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

Fas and Fas ligand expression is elevated in prostatic intraepithelial neoplasia and prostatic adenocarcinoma

Jiang, J., Ulbright, T. M., Zhang, S., Eckert, G. J., Kao, C., Gardner, T. A., Koch, M. O., Eble, J. N. & Cheng, L., Jul 15 2002, In : Cancer. 95, 2, p. 296-300 5 p.

Research output: Contribution to journalArticle

30 Scopus citations

Fas-Fas ligand signaling pathway mediates an interleukin-12-induced rejection of a murine prostate tumor system

Zhang, S., Zeng, G., Kao, C., Gardner, T., Sweeney, C., Yang, N. S., Eble, J. N. & Cheng, L., Sep 15 2002, In : Prostate. 53, 1, p. 69-76 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Fas ligand delivery by a prostate-restricted replicative adenovirus enhances safety and antitumor efficacy

Li, X., Liu, Y. H., Zhang, Y. P., Zhang, S., Pu, X., Gardner, T. A., Jeng, M. H. & Kao, C., Sep 15 2007, In : Clinical Cancer Research. 13, 18, p. 5463-5473 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

Flexible transinguinal laparoscopy to assess the contralateral ring in pediatric inguinal hernias

Pavlovich, C. P., Gmyrek, G. A., Gardner, T. A., Poppas, D. P. & Mininberg, D. T., Nov 2 1998, In : Techniques in urology. 4, 3, p. 141-144 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Gemcitabine, cisplatin, and sunitinib for metastatic urothelial carcinoma and as preoperative therapy for muscle-invasive bladder cancer

Galsky, M. D., Hahn, N. M., Powles, T., Hellerstedt, B. A., Lerner, S. P., Gardner, T. A., Yu, M., O'Rourke, M., Vogelzang, N. J., Kocs, D., McKenney, S. A., Melnyk, A. M., Hutson, T. E., Rauch, M., Wang, Y., Asmar, L. & Sonpavde, G., Jun 1 2013, In : Clinical Genitourinary Cancer. 11, 2, p. 175-181 7 p.

Research output: Contribution to journalArticle

65 Scopus citations

Gene therapy for prostate cancer by controlling adenovirus E1a and E4 gene expression with PSES enhancer

Li, X., Zhang, Y. P., Kim, H. S., Bae, K. H., Stantz, K. M., Lee, S. J., Jung, C., Jiménez, J. A., Gardner, T. A., Jeng, M. H. & Kao, C., Mar 1 2005, In : Cancer Research. 65, 5, p. 1941-1951 11 p.

Research output: Contribution to journalArticle

57 Scopus citations

High-Level Expression of EphA2 Receptor Tyrosine Kinase in Prostatic Intraepithelial Neoplasia

Zeng, G., Hu, Z., Kinch, M. S., Pan, C. X., Flockhart, D. A., Kao, C., Gardner, T. A., Zhang, S., Li, L., Baldridge, L. A., Koch, M. O., Ulbright, T. M., Eble, J. N. & Cheng, L., Dec 2003, In : American Journal of Pathology. 163, 6, p. 2271-2276 6 p.

Research output: Contribution to journalArticle

92 Scopus citations

HOXB13 is downregulated in colorectal cancer to confer TCF4-mediated transactivation

Jung, C., Kim, R. S., Zhang, H., Lee, S. J., Sheng, H., Loehrer, P. J., Gardner, T. A., Jeng, M. H. & Kao, C., Jun 20 2005, In : British Journal of Cancer. 92, 12, p. 2233-2239 7 p.

Research output: Contribution to journalArticle

55 Scopus citations

Humoral immune response against nontargeted tumor antigens after treatment with sipuleucel-T and its association with improved clinical outcome

Thakurta, D. G., Sheikh, N. A., Fan, L. Q., Kandadi, H., Meagher, T. C., Hall, S. J., Kantoff, P. W., Higano, C. S., Small, E. J., Gardner, T. A., Bailey, K., Vu, T., Devries, T., Whitmore, J. B., Frohlich, M. W., Trager, J. B. & Drake, C. G., Aug 15 2015, In : Clinical Cancer Research. 21, 16, p. 3619-3630 12 p.

Research output: Contribution to journalArticle

59 Scopus citations