Thomas Gardner

  • 3381 Citations
  • 31 h-Index
1977 …2018
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Publications 1994 2018

  • 3381 Citations
  • 31 h-Index
  • 110 Article
  • 7 Conference contribution
  • 2 Chapter
  • 1 Comment/debate
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Article
53 Citations (Scopus)

[11C]Choline as a PET biomarker for assessment of prostate cancer tumor models

Zheng, Q-H., Gardner, T., Raikwar, S., Kao, C., Stone, K. L., Martinez, T. D., Mock, B. H., Fei, X., Wang, J. Q. & Hutchins, G., Jun 1 2004, In : Bioorganic and Medicinal Chemistry. 12, 11, p. 2887-2893 7 p.

Research output: Contribution to journalArticle

Positron emission tomography
Biomarkers
Choline
Positron-Emission Tomography
Tumors
128 Citations (Scopus)

Aberrant expression of CARM1, a transcriptional coactivator of androgen receptor, in the development of prostate carcinoma and androgen-independent status

Hong, H., Kao, C., Jeng, M. H., Eble, J., Koch, M., Gardner, T., Zhang, S., Li, L., Pan, C. X., Hu, Z., MacLennan, G. T. & Cheng, L., Jul 1 2004, In : Cancer. 101, 1, p. 83-89 7 p.

Research output: Contribution to journalArticle

Androgen Receptors
Androgens
Prostate
Carcinoma
Prostatic Intraepithelial Neoplasia
20 Citations (Scopus)
Prostate-Specific Antigen
Prostatectomy
Recurrence
14 Citations (Scopus)

A conditionally replicative, Wnt/Β-catenin pathway-based adenovirus therapy for anaplastic thyroid cancer

Abbosh, P. H., Li, X., Li, L., Gardner, T., Kao, C. & Nephew, K., Apr 2007, In : Cancer Gene Therapy. 14, 4, p. 399-408 10 p.

Research output: Contribution to journalArticle

Catenins
Wnt Signaling Pathway
Adenoviridae
Thyroid Neoplasms
Therapeutics
133 Citations (Scopus)

A conditional replication-competent adenoviral vector, AD-OC-E1a, to cotarget prostate cancer and bone stroma in an experimental model of androgen-independent prostate cancer bone metastasis

Matsubara, S., Wada, Y., Gardner, T., Egawa, M., Par, M. S., Hsieh, C. L., Zhau, H. E., Kao, C., Kamidono, S., Gillenwater, J. Y. & Chung, L. W. K., Aug 15 2001, In : Cancer Research. 61, 16, p. 6012-6019 8 p.

Research output: Contribution to journalArticle

Bone Neoplasms
Osteocalcin
Androgens
Prostatic Neoplasms
Theoretical Models
30 Citations (Scopus)

Adenoviral vectors expressing human endostatin-angiostatin and soluble Tie2: Enhanced suppression of tumor growth and antiangiogenic effects in a prostate tumor model

Raikwar, S. P., Temm, C. J., Raikwar, N. S., Kao, C., Molitoris, B. & Gardner, T., Dec 2005, In : Molecular Therapy. 12, 6, p. 1091-1100 10 p.

Research output: Contribution to journalArticle

Angiostatins
Endostatins
Prostate
Growth
Prostatic Neoplasms
7 Citations (Scopus)

Adenovirus-mediated suicide-gene therapy in an orthotopic murine bladder tumor model

Cheon, J., Moon, D. G., Cho, H. Y., Park, H. S., Kim, J. J., Gardner, T. & Kao, C., 2002, In : International Journal of Urology. 9, 5, p. 261-267 7 p.

Research output: Contribution to journalArticle

Rous sarcoma virus
Ganciclovir
Urinary Bladder Neoplasms
Adenoviridae
Genetic Therapy
25 Citations (Scopus)

Allelic Loss of the Active X Chromosome during Bladder Carcinogenesis

Cheng, L., MacLennan, G. T., Pan, C. X., Jones, T. D., Moore, C. R., Zhang, S., Gu, J., Patel, N. B., Kao, C. & Gardner, T., Feb 2004, In : Archives of Pathology and Laboratory Medicine. 128, 2, p. 187-190 4 p.

Research output: Contribution to journalArticle

Loss of Heterozygosity
X Chromosome
X Chromosome Inactivation
Carcinogenesis
Urinary Bladder
39 Citations (Scopus)
Prostatectomy
Adipose Tissue
Prostate
Carcinoma
Lymph Node Excision
32 Citations (Scopus)
Vascular Endothelial Growth Factor A
Androgens
Prostatic Neoplasms
Castration
Growth
9 Citations (Scopus)

An Improved Total Synthesis of PET HSV-tk Gene Expression Imaging Agent 9-[(3-[18F]Fluoro-1-hydroxy-2-propoxy)methyl]guanine ([ 18F]FHPG)

Wang, J. Q., Zheng, Q-H., Fei, X., Liu, X., Gardner, T., Kao, C., Raikwar, S. P., Glick-Wilson, B. E., Sullivan, M. L., Mock, B. H. & Hutchins, G., 2004, In : Synthetic Communications. 34, 5, p. 917-932 16 p.

Research output: Contribution to journalArticle

Guanine
Gene expression
Imaging techniques
2-Propanol
Silicon Dioxide
9 Citations (Scopus)

An Improved Total Synthesis of PET HSV-tk Gene Reporter Probe 9-(4-[ 18F]Fluoro-3-hydroxymethylbutyl)guanine ([18F]FHBG)

Zheng, Q-H., Wang, J. Q., Liu, X., Fei, X., Mock, B. H., Glick-Wilson, B. E., Sullivan, M. L., Raikwar, S. P., Gardner, T., Kao, C. & Hutchins, G., 2004, In : Synthetic Communications. 34, 4, p. 689-704 16 p.

Research output: Contribution to journalArticle

Guanine
Genes
Silicon Dioxide
Purification
Substitution reactions
5 Citations (Scopus)

Anti-angiogenic gene therapy for metastatic renal cell carcinoma produces tumor growth suppression in an athymic nude mouse model

Mellon, M. J., Ahn, M., Jiménez, J. A., Kao, C. & Gardner, T., Feb 2008, In : Journal of Urology. 179, 2, p. 737-742 6 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Nude Mice
Genetic Therapy
Growth
Blood Vessels
10 Citations (Scopus)

Antitumor activity of Ad-IU2, a prostate-specific replication-competent adenovirus encoding the apoptosis inducer, TRAIL

Jiménez, J. A., Li, X., Zhang, Y. P., Bae, K. H., Mohammadi, Y., Pandya, P., Kao, C. & Gardner, T., Mar 2010, In : Cancer Gene Therapy. 17, 3, p. 180-191 12 p.

Research output: Contribution to journalArticle

Adenoviridae
Prostate
Apoptosis
Prostate-Specific Antigen
Androgens
17 Citations (Scopus)

Anti-tumor efficacy of a transcriptional replication-competent adenovirus, Ad-OC-E1a, for osteosarcoma pulmonary metastasis

Li, X., Jung, C., Liu, Y. H., Bae, K. H., Zhang, Y. P., Zhang, H. J., VanderPutten, D., Jeng, M. H., Gardner, T. & Kao, C., Jun 2006, In : Journal of Gene Medicine. 8, 6, p. 679-689 11 p.

Research output: Contribution to journalArticle

Osteocalcin
Osteosarcoma
Adenoviridae
Neoplasm Metastasis
Lung
9 Citations (Scopus)
Prostatectomy
Urinary Bladder
Randomized Controlled Trials
Prostatic Neoplasms
Suburethral Slings
16 Citations (Scopus)

A phase II trial of dovitinib in BCG-unresponsive urothelial carcinoma with FGFR3 mutations or overexpression: Hoosier Cancer Research Network trial HCRN 12-157

Hahn, N. M., Bivalacqua, T. J., Ross, A. E., Netto, G. J., Baras, A., Park, J. C., Chapman, C., Masterson, T., Koch, M., Bihrle, R., Foster, R., Gardner, T., Cheng, L., Jones, D. R., McElyea, K., Sandusky, G., Breen, T., Liu, Z., Albany, C., Moore, M. L. & 9 others, Loman, R. L., Reed, A., Turner, S. A., De Abreu, F. B., Gallagher, T., Tsongalis, G. J., Plimack, E. R., Greenberg, R. E. & Geynisman, D. M., Jun 15 2017, In : Clinical Cancer Research. 23, 12, p. 3003-3011 9 p.

Research output: Contribution to journalArticle

Mycobacterium bovis
Carcinoma
Mutation
Research
Neoplasms
3 Citations (Scopus)

A potential for tissue restrictive gene therapy in renal cell carcinoma using MN/CA IX promoter

Ou, Y. C., Gardner, T., Kao, C., Zhau, H. E. & Chung, L. W., Mar 2005, In : Anticancer Research. 25, 2 A, p. 881-886 6 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Genetic Therapy
HeLa Cells
Cell Line
Poisons
44 Citations (Scopus)

A randomized phase II trial of sipuleucel-T with concurrent versus sequential abiraterone acetate plus prednisone in metastatic castration-resistant prostate cancer

Small, E. J., Lance, R. S., Gardner, T., Karsh, L. I., Fong, L., McCoy, C., De Vries, T., Sheikh, N. A., GuhaThakurta, D., Chang, N., Redfern, C. H. & Shore, N. D., Sep 1 2015, In : Clinical Cancer Research. 21, 17, p. 3862-3869 8 p.

Research output: Contribution to journalArticle

Castration
Prednisone
Prostatic Neoplasms
Antigen-Presenting Cells
Cell Count
2 Citations (Scopus)

Assessing Cost of Robotic Utilization in Partial Nephrectomy with Increasing Utilization

Bahler, C., Monn, M. F., Flack, C. K., Gramm, A. R., Gardner, T. & Sundaram, C., Aug 1 2018, In : Journal of Endourology. 32, 8, p. 710-716 7 p.

Research output: Contribution to journalArticle

Robotics
Nephrectomy
Costs and Cost Analysis
Linear Models
Fees and Charges
22 Citations (Scopus)

A transient increase in eosinophils is associated with prolonged survival in men with metastatic castration-resistant prostate cancer who receive sipuleucel-T

McNeel, D. G., Gardner, T., Higano, C. S., Kantoff, P. W., Small, E. J., Wener, M. H., Sims, R. B., DeVries, T., Sheikh, N. A. & Dreicer, R., Oct 1 2014, In : Cancer immunology research. 2, 10, p. 988-999 12 p.

Research output: Contribution to journalArticle

Castration
Eosinophils
Prostatic Neoplasms
Survival
Confidence Intervals
22 Citations (Scopus)
Prostate-Specific Antigen
Prostatectomy
Disease-Free Survival
Prostatic Neoplasms
Recurrence
140 Citations (Scopus)

Biology of Childhood Osteogenic Sarcoma and Potential Targets for Therapeutic Development: Meeting Summary

Gorlick, R., Anderson, P., Andrulis, I., Arndt, C., Beardsley, G. P., Bernstein, M., Bridge, J., Cheung, N. K., Dome, J. S., Ebb, D., Gardner, T., Gebhardt, M., Grier, H., Hansen, M., Healey, J., Helman, L., Hock, J., Houghton, J., Houghton, P., Huvos, A. & 19 others, Khanna, C., Kieran, M., Kleinerman, E., Ladanyi, M., Lau, C., Malkin, D., Marina, N., Meltzer, P., Meyers, P., Schofield, D., Schwartz, C., Smith, M. A., Toretsky, J., Tsokos, M., Wexler, L., Wigginton, J., Withrow, S., Schoenfeldt, M. & Anderson, B., Nov 15 2003, In : Clinical Cancer Research. 9, 15, p. 5442-5453 12 p.

Research output: Contribution to journalArticle

Osteosarcoma
Bone Neoplasms
National Cancer Institute (U.S.)
Program Evaluation
Therapeutics
54 Citations (Scopus)

Chemogene therapy: Osteocalcin promoter-based suicide gene therapy in combination with methotrexate in a marine osteosarcoma model

Cheon, J., Ko, S. C., Gardner, T., Shirakawa, T., Gotoh, A., Kao, C. & Chung, L. W. K., 1997, In : Cancer Gene Therapy. 4, 6, p. 359-365 7 p.

Research output: Contribution to journalArticle

Osteocalcin
Osteosarcoma
Methotrexate
Genetic Therapy
Suicide
15 Citations (Scopus)

Combination therapy of androgen-independent prostate cancer using a prostate restricted replicative adenovirus and a replication-defective adenovirus encoding human endostatin-angiostatin fusion gene

Li, X., Raikwar, S. P., Liu, Y. H., Lee, S. J., Zhang, Y. P., Zhang, S., Cheng, L., Lee, S. D., Juliar, B. E., Gardner, T., Jeng, M. H. & Kao, C., Mar 2006, In : Molecular Cancer Therapeutics. 5, 3, p. 676-684 9 p.

Research output: Contribution to journalArticle

Angiostatins
Endostatins
Human Adenoviruses
Gene Fusion
Adenoviridae
37 Citations (Scopus)

Comparison of laparoscopic pyeloplasty with and without robotic assistance.

Bernie, J. E., Venkatesh, R., Brown, J., Gardner, T. & Sundaram, C., 2005, In : JSLS : Journal of the Society of Laparoendoscopic Surgeons / Society of Laparoendoscopic Surgeons. 9, 3, p. 258-261 4 p.

Research output: Contribution to journalArticle

Robotics
Anastomotic Leak
Learning Curve
Computer-Assisted Image Processing
Furosemide
27 Citations (Scopus)
Nephrectomy
Hand
Length of Stay
Operative Time
Costs and Cost Analysis
5 Citations (Scopus)

Concurrent malakoplakla and primary squamous cell carcinoma arising in long-standing chronic cystitis

Ngadiman, S., Hoda, S. A., Campbell, W. G., Gardner, T. & May, M., 1994, In : British Journal of Urology. 74, 6, p. 801-802 2 p.

Research output: Contribution to journalArticle

Malacoplakia
Cystitis
Fatal Outcome
Urinary Bladder Neoplasms
Squamous Cell Carcinoma
11 Citations (Scopus)

Conversions in laparoscopic renal surgery: Causes and outcomes

Ivey, B. S., Lucas, S. M., Meyer, C. A., Emley, T. E., Bey, A., Gardner, T. & Sundaram, C., Jul 1 2011, In : Journal of Endourology. 25, 7, p. 1167-1173 7 p.

Research output: Contribution to journalArticle

Laparoscopy
Kidney
Hand
Conversion to Open Surgery
Autosomal Dominant Polycystic Kidney
38 Citations (Scopus)

Cotargeting tumor and stroma in a novel chimeric tumor model involving the growth of both human prostate cancer and bone stromal cells

Hsieh, C. L., Gardner, T., Miao, L., Balian, G. & Chung, L. W. K., Feb 2004, In : Cancer Gene Therapy. 11, 2, p. 148-155 8 p.

Research output: Contribution to journalArticle

Bone Neoplasms
Stromal Cells
Prostatic Neoplasms
Growth
Neoplasms
18 Citations (Scopus)

Current status of anti-angiogenesis therapy for prostate cancer{star, open}

Jiménez, J. A., Kao, C., Raikwar, S. & Gardner, T., May 2006, In : Urologic Oncology: Seminars and Original Investigations. 24, 3, p. 260-268 9 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Therapeutics
Neoplasms
Neoplasm Metastasis
Mortality
31 Citations (Scopus)

Cytotoxicity of adenoviral-mediated cytosine deaminase plus 5- fluorocytosine gene therapy is superior to thymidine kinase plus acyclovir in a human renal cell carcinoma model

Shirakawa, T., Gardner, T., Ko, S. C., Bander, N., Woo, S., Gotoh, A., Kamidono, S., Chung, L. W. K. & Kao, C., Sep 1999, In : Journal of Urology. 162, 3 I, p. 949-954 6 p.

Research output: Contribution to journalArticle

Cytosine Deaminase
Flucytosine
Acyclovir
Thymidine Kinase
Renal Cell Carcinoma
3 Citations (Scopus)

Development of human chorionic gonadotropin subunit-beta promoter-based toxic gene therapy for testicular cancer.

Shirakawa, T., Gotoh, A., Zhang, Z., Kao, C., Chung, L. W. K. & Gardner, T., Mar 2004, In : Urology. 63, 3, p. 613-618 6 p.

Research output: Contribution to journalArticle

Chorionic Gonadotropin, beta Subunit, Human
Poisons
Testicular Neoplasms
Chorionic Gonadotropin
Genetic Therapy
101 Citations (Scopus)

Development of prostate-specific antigen promoter-based gene therapy for androgen-independent human prostate cancer

Gotoh, A., Ko, S. C., Shirakawa, T., Cheon, J., Kao, C., Miyamoto, T., Gardner, T., Ho, L. J., Cleutjens, C. B. J., Trapman, J., Graham, F. L. & Chung, L. W. K., Jul 1998, In : Journal of Urology. 160, 1, p. 220-229 10 p.

Research output: Contribution to journalArticle

Prostate-Specific Antigen
Genetic Therapy
Androgens
Prostatic Neoplasms
Acyclovir
11 Citations (Scopus)

Diagnostic flexible peritoneoscopy: Assessment of the contralateral internal inguinal ring during unilateral herniorrhaphy

Gardner, T., Ostad, M. & Mininberg, D. T., Oct 1998, In : Journal of Pediatric Surgery. 33, 10, p. 1486-1489 4 p.

Research output: Contribution to journalArticle

Inguinal Canal
Herniorrhaphy
Hernia
Laparoscopy
Cystoscopes
13 Citations (Scopus)

Differential expression of osteocalcin during the metastatic progression of prostate cancer

Gardner, T., Lee, S. J., Lee, S. D., Li, X., Shirakawa, T., Kwon, D. D., Park, R. Y., Ahn, K. Y. & Jung, C., 2009, In : Oncology Reports. 21, 4, p. 903-908 6 p.

Research output: Contribution to journalArticle

Osteocalcin
Prostatic Neoplasms
Prostate
Bone and Bones
Neoplasms
21 Citations (Scopus)

Drug-resistant human bladder-cancer cells are more sensitive to adenovirus-mediated wild-type p53 gene therapy compared to drug-sensitive cells

Shirakawa, T., Sasaki, R., Gardner, T., Kao, C., Zhang, Z. J., Sugimura, K., Matsuo, M., Kamidono, S. & Gotoh, A., Oct 15 2001, In : International Journal of Cancer. 94, 2, p. 282-289 8 p.

Research output: Contribution to journalArticle

p53 Genes
Urinary Bladder Neoplasms
Adenoviridae
Genetic Therapy
Cell Line
45 Citations (Scopus)

Early catheter removal after radical retropubic prostatectomy: Long-term followup

Koch, M., Nayee, A. H., Sloan, J., Gardner, T., Wahle, G. R., Bihrle, R. & Foster, R., Jun 1 2003, In : Journal of Urology. 169, 6, p. 2170-2172 3 p.

Research output: Contribution to journalArticle

Prostatectomy
Catheters
Prostatic Neoplasms
Indwelling Catheters
Drainage

Editorial comment

Liu, N. W. & Gardner, T., 2014, In : Urology. 83, 5, p. 1087 1 p.

Research output: Contribution to journalArticle

Cryosurgery
Kidney Neoplasms
Laparoscopy

Editorial comment

Liu, N. W. & Gardner, T., Dec 1 2014, In : Urology. 84, 6, p. 1323-1324 2 p.

Research output: Contribution to journalArticle

Local Neoplasm Recurrences
Unnecessary Procedures
Seminoma
Testicular Neoplasms
2 Citations (Scopus)

Editorial comment

Gardner, T., Aug 2013, In : Journal of Urology. 190, 2, p. 710 1 p.

Research output: Contribution to journalArticle

Transrectal High-Intensity Focused Ultrasound
Prostatic Neoplasms

Editorial Comment

Gardner, T., Bahler, C. & Gillhaus, P., Aug 1 2015, In : Urology. 86, 2, p. 319-320 2 p.

Research output: Contribution to journalArticle

Kidney Neoplasms
Recovery of Function
Nephrectomy
Renal Cell Carcinoma
Kidney
10 Citations (Scopus)

Elevated activated partial thromboplastin time during administration of first-generation adenoviral vectors for gene therapy for prostate cancer: Identification of lupus anticoagulants

Malaeb, B. S., Gardner, T., Margulis, V., Yang, L., Gillenwater, J. Y., Chung, L. W. K., Macik, G. & Koeneman, K. S., Oct 2005, In : Urology. 66, 4, p. 830-834 5 p.

Research output: Contribution to journalArticle

Lupus Coagulation Inhibitor
Partial Thromboplastin Time
Genetic Therapy
Prostatic Neoplasms
Ischium
24 Citations (Scopus)

Enhanced combined tumor-specific oncolysis and suicide gene therapy for prostate cancer using M6 promoter

Ahn, M., Lee, S. J., Li, X., Jiménez, J. A., Zhang, Y. P., Bae, K. H., Mohammadi, Y., Kao, C. & Gardner, T., Jan 2009, In : Cancer Gene Therapy. 16, 1, p. 73-82 10 p.

Research output: Contribution to journalArticle

Genetic Therapy
Suicide
Prostatic Neoplasms
Neoplasms
Androgens
9 Citations (Scopus)

Estimation of radiation dosimetry for 68Ga-HBED-CC (PSMA-11) in patients with suspected recurrence of prostate cancer

Green, M., Eitel, J. A., Fletcher, J., Mathias, C. J., Tann, M. A., Territo, W., Polson, H., Hutchins, G., Gardner, T. & Koch, M., Mar 1 2017, In : Nuclear Medicine and Biology. 46, p. 32-35 4 p.

Research output: Contribution to journalArticle

Radiometry
Prostatic Neoplasms
Recurrence
Pelvis
Injections
23 Citations (Scopus)

Evaluation of hydrogel tissue sealant in porcine laparoscopic partial-nephrectomy model

Bernie, J. E., Ng, J., Bargman, V., Gardner, T., Cheng, L. & Sundaram, C., Nov 2005, In : Journal of Endourology. 19, 9, p. 1122-1126 5 p.

Research output: Contribution to journalArticle

Hydrogel
Nephrectomy
Fibrin Tissue Adhesive
Swine
Hemostatic Techniques
30 Citations (Scopus)

Fas and Fas ligand expression is elevated in prostatic intraepithelial neoplasia and prostatic adenocarcinoma

Jiang, J., Ulbright, T., Zhang, S., Eckert, G. J., Kao, C., Gardner, T., Koch, M., Eble, J. & Cheng, L., Jul 15 2002, In : Cancer. 95, 2, p. 296-300 5 p.

Research output: Contribution to journalArticle

Prostatic Intraepithelial Neoplasia
Fas Ligand Protein
Adenocarcinoma
Prostate
Staining and Labeling
8 Citations (Scopus)

Fas-Fas ligand signaling pathway mediates an interleukin-12-induced rejection of a murine prostate tumor system

Zhang, S., Zeng, G., Kao, C., Gardner, T., Sweeney, C., Yang, N. S., Eble, J. & Cheng, L., Sep 15 2002, In : Prostate. 53, 1, p. 69-76 8 p.

Research output: Contribution to journalArticle

Fas Ligand Protein
Interleukin-12
Prostate
Neoplasms
Apoptosis
22 Citations (Scopus)

Fas ligand delivery by a prostate-restricted replicative adenovirus enhances safety and antitumor efficacy

Li, X., Liu, Y. H., Zhang, Y. P., Zhang, S., Pu, X., Gardner, T., Jeng, M. H. & Kao, C., Sep 15 2007, In : Clinical Cancer Research. 13, 18, p. 5463-5473 11 p.

Research output: Contribution to journalArticle

Fas Ligand Protein
Adenoviridae
Prostate
Safety
Prostatic Neoplasms
6 Citations (Scopus)

Flexible transinguinal laparoscopy to assess the contralateral ring in pediatric inguinal hernias

Pavlovich, C. P., Gmyrek, G. A., Gardner, T., Poppas, D. P. & Mininberg, D. T., 1998, In : Techniques in Urology. 4, 3, p. 141-144 4 p.

Research output: Contribution to journalArticle

Inguinal Hernia
Laparoscopy
Pediatrics
Cystoscopes
Lenses