Thomas Gardner

  • 3459 Citations
  • 31 h-Index
1977 …2020

Research output per year

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Publications

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Article
2005

Transcriptional targeting modalities in breast cancer gene therapy using adenovirus vectors controlled by α-lactalbumin promoter

Li, X., Zhang, J., Gao, H., Vieth, E., Bae, K. H., Zhang, Y. P., Lee, S. J., Raikwar, S., Gardner, T. A., Hutchins, G. D., VanderPutten, D., Kao, C. & Jeng, M. H., Dec 1 2005, In : Molecular cancer therapeutics. 4, 12, p. 1850-1859 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Utility of the fourth arm to facilitate robot-assisted laparoscopic radical prostatectomy

Sundaram, C. P., Koch, M. O., Gardner, T. & Bernie, J. E., Jan 1 2005, In : BJU International. 95, 1, p. 183-186 4 p.

Research output: Contribution to journalArticle

10 Scopus citations
2004

[11C]Choline as a PET biomarker for assessment of prostate cancer tumor models

Zheng, Q. H., Gardner, T. A., Raikwar, S., Kao, C., Stone, K. L., Martinez, T. D., Mock, B. H., Fei, X., Wang, J. Q. & Hutchins, G. D., Jun 1 2004, In : Bioorganic and Medicinal Chemistry. 12, 11, p. 2887-2893 7 p.

Research output: Contribution to journalArticle

53 Scopus citations

Aberrant expression of CARM1, a transcriptional coactivator of androgen receptor, in the development of prostate carcinoma and androgen-independent status

Hong, H., Kao, C., Jeng, M. H., Eble, J. N., Koch, M. O., Gardner, T. A., Zhang, S., Li, L., Pan, C. X., Hu, Z., MacLennan, G. T. & Cheng, L., Jul 1 2004, In : Cancer. 101, 1, p. 83-89 7 p.

Research output: Contribution to journalArticle

136 Scopus citations

Allelic Loss of the Active X Chromosome during Bladder Carcinogenesis

Cheng, L., MacLennan, G. T., Pan, C. X., Jones, T. D., Moore, C. R., Zhang, S., Gu, J., Patel, N. B., Kao, C. & Gardner, T. A., Feb 1 2004, In : Archives of Pathology and Laboratory Medicine. 128, 2, p. 187-190 4 p.

Research output: Contribution to journalArticle

25 Scopus citations
33 Scopus citations

An Improved Total Synthesis of PET HSV-tk Gene Expression Imaging Agent 9-[(3-[18F]Fluoro-1-hydroxy-2-propoxy)methyl]guanine ([ 18F]FHPG)

Wang, J. Q., Zheng, Q. H., Fei, X., Liu, X., Gardner, T. A., Kao, C., Raikwar, S. P., Glick-Wilson, B. E., Sullivan, M. L., Mock, B. H. & Hutchins, G. D., Mar 31 2004, In : Synthetic Communications. 34, 5, p. 917-932 16 p.

Research output: Contribution to journalArticle

9 Scopus citations

An Improved Total Synthesis of PET HSV-tk Gene Reporter Probe 9-(4-[ 18F]Fluoro-3-hydroxymethylbutyl)guanine ([18F]FHBG)

Zheng, Q. H., Wang, J. Q., Liu, X., Fei, X., Mock, B. H., Glick-Wilson, B. E., Sullivan, M. L., Raikwar, S. P., Gardner, T. A., Kao, C. & Hutchins, G. D., Mar 26 2004, In : Synthetic Communications. 34, 4, p. 689-704 16 p.

Research output: Contribution to journalArticle

10 Scopus citations

Cotargeting tumor and stroma in a novel chimeric tumor model involving the growth of both human prostate cancer and bone stromal cells

Hsieh, C. L., Gardner, T. A., Miao, L., Balian, G. & Chung, L. W. K., Feb 1 2004, In : Cancer Gene Therapy. 11, 2, p. 148-155 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

Development of human chorionic gonadotropin subunit-beta promoter-based toxic gene therapy for testicular cancer.

Shirakawa, T., Gotoh, A., Zhang, Z., Kao, C., Chung, L. W. K. & Gardner, T. A., Mar 2004, In : Urology. 63, 3, p. 613-618 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Nuclear factor-κB is constitutively activated in prostate cancer in vitro and is overexpressed in prostatic intraepithelial neoplasia and adenocarcinoma of the prostate

Sweeney, C., Li, L., Shanmugam, R., Bhat-Nakshatri, P., Jayaprakasan, V., Baldridge, L. A., Gardner, T., Smith, M., Nakshatri, H. & Cheng, L., Aug 15 2004, In : Clinical Cancer Research. 10, 16, p. 5501-5507 7 p.

Research output: Contribution to journalArticle

147 Scopus citations

Targeting prostate cancer with conditionally replicative adenovirus using PSMA enhancer

Lee, S. J., Zhang, Y., Lee, S. D., Jung, C., Li, X., Kim, H. S., Bae, K. H., Jeng, M. H., Kao, C. & Gardner, T., Dec 1 2004, In : Molecular Therapy. 10, 6, p. 1051-1058 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Transitional cell carcinoma of the bladder following augmentation cystoplasty for the neuropathic bladder

Soergel, T. M., Cain, M. P., Misseri, R., Gardner, T. A., Koch, M. O., Rink, R. C., Strand, W., Austin, P., Shortliffe, L., Diamond, D. & Park, J., Oct 2004, In : Journal of Urology. 172, 4 II, p. 1649-1652 4 p.

Research output: Contribution to journalArticle

148 Scopus citations

Tumor-specific gene therapy for uterine cervical cancer using MN/CA9-directed replication-competent adenovirus

Lim, H. Y., Ahn, M., Chung, H. C., Gardner, T. A., Kao, C., Lee, S. J. & Kim, S. J., Aug 2004, In : Cancer gene therapy. 11, 8, p. 532-538 7 p.

Research output: Contribution to journalArticle

11 Scopus citations
2003
39 Scopus citations
23 Scopus citations

Biology of Childhood Osteogenic Sarcoma and Potential Targets for Therapeutic Development: Meeting Summary

Gorlick, R., Anderson, P., Andrulis, I., Arndt, C., Beardsley, G. P., Bernstein, M., Bridge, J., Cheung, N. K., Dome, J. S., Ebb, D., Gardner, T., Gebhardt, M., Grier, H., Hansen, M., Healey, J., Helman, L., Hock, J., Houghton, J., Houghton, P., Huvos, A. & 19 others, Khanna, C., Kieran, M., Kleinerman, E., Ladanyi, M., Lau, C., Malkin, D., Marina, N., Meltzer, P., Meyers, P., Schofield, D., Schwartz, C., Smith, M. A., Toretsky, J., Tsokos, M., Wexler, L., Wigginton, J., Withrow, S., Schoenfeldt, M. & Anderson, B., Nov 15 2003, In : Clinical Cancer Research. 9, 15, p. 5442-5453 12 p.

Research output: Contribution to journalArticle

141 Scopus citations

Early catheter removal after radical retropubic prostatectomy: Long-term followup

Koch, M. O., Nayee, A. H., Sloan, J., Gardner, T., Wahle, G. R., Bihrle, R. & Foster, R. S., Jun 1 2003, In : Journal of Urology. 169, 6, p. 2170-2172 3 p.

Research output: Contribution to journalArticle

46 Scopus citations

High-Level Expression of EphA2 Receptor Tyrosine Kinase in Prostatic Intraepithelial Neoplasia

Zeng, G., Hu, Z., Kinch, M. S., Pan, C. X., Flockhart, D. A., Kao, C., Gardner, T. A., Zhang, S., Li, L., Baldridge, L. A., Koch, M. O., Ulbright, T. M., Eble, J. N. & Cheng, L., Dec 2003, In : American Journal of Pathology. 163, 6, p. 2271-2276 6 p.

Research output: Contribution to journalArticle

92 Scopus citations

Laparoscopic partial kidney ablation with high intensity focused ultrasound

Paterson, R. F., Barret, E., Siqueira, T. M., Gardner, T. A., Tavakkoli, J., Rao, V. V., Sanghvi, N. T., Cheng, L. & Shalhav, A. L., Jan 1 2003, In : Journal of Urology. 169, 1, p. 347-351 5 p.

Research output: Contribution to journalArticle

44 Scopus citations

Nephrectomy for metastatic renal cell carcinoma: Indiana University experience

Mosharafa, A., Koch, M., Shalhav, A., Gardner, T., Logan, T., Bihrle, R. & Foster, R., Oct 1 2003, In : Urology. 62, 4, p. 636-640 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

New targets for therapy in prostate cancer: Modulation of stromal-epithelial interactions

Chung, L. W. K., Hsieh, C. L., Law, A., Sung, S. Y., Gardner, T. A., Egawa, M., Matsubara, S. & Zhau, H. E., Nov 2003, In : Urology. 62, 5 SUPPL. 1, p. 44-54 11 p.

Research output: Contribution to journalArticle

48 Scopus citations

NFATc1 with AP-3 site binding specificity mediates gene expression of prostate-specific-membrane-antigen.

Lee, S. J., Lee, K. R., Yang, X., Jung, C., Gardner, T., Kim, H. S., Jeng, M. H. & Kao, C., Jul 18 2003, In : Journal of molecular biology. 330, 4, p. 749-760 12 p.

Research output: Contribution to journalArticle

22 Scopus citations

Phase I dose escalation clinical trial of adenovirus vector carrying osteocalcin promoter-driven herpes simplex virus thymidine kinase in localized and metastatic hormone-refractory prostate cancer

Kubo, H., Gardner, T. A., Wada, Y., Koeneman, K. S., Gotoh, A., Yang, L., Kao, C., Lim, S. D., Amin, M. B., Yang, H., Black, M. E., Matsubara, S., Nakagawa, M., Gillenwater, J. Y., Zhau, H. E. & Chung, L. W. K., Feb 10 2003, In : Human gene therapy. 14, 3, p. 227-241 15 p.

Research output: Contribution to journalArticle

101 Scopus citations
2002

Adenovirus-mediated suicide-gene therapy in an orthotopic murine bladder tumor model

Cheon, J., Moon, D. G., Cho, H. Y., Park, H. S., Kim, J. J., Gardner, T. A. & Kao, C., Jun 26 2002, In : International Journal of Urology. 9, 5, p. 261-267 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Fas and Fas ligand expression is elevated in prostatic intraepithelial neoplasia and prostatic adenocarcinoma

Jiang, J., Ulbright, T. M., Zhang, S., Eckert, G. J., Kao, C., Gardner, T. A., Koch, M. O., Eble, J. N. & Cheng, L., Jul 15 2002, In : Cancer. 95, 2, p. 296-300 5 p.

Research output: Contribution to journalArticle

30 Scopus citations

Fas-Fas ligand signaling pathway mediates an interleukin-12-induced rejection of a murine prostate tumor system

Zhang, S., Zeng, G., Kao, C., Gardner, T., Sweeney, C., Yang, N. S., Eble, J. N. & Cheng, L., Sep 15 2002, In : Prostate. 53, 1, p. 69-76 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Major complications in 213 laparoscopic nephrectomy cases: The Indianapolis experience

Siqueira, T. M., Kuo, R. L., Gardner, T. A., Paterson, R. F., Stevens, L. H., Lingeman, J. E., Koch, M. O. & Shalhav, A. L., Oct 2002, In : Journal of Urology. 168, 4 I, p. 1361-1365 5 p.

Research output: Contribution to journalArticle

89 Scopus citations

Manual specimen retrieval without a pneumoperitoneum preserving device for laparoscopic live donor nephrectomy

Shalhav, A. L., Siqueira, T. M., Gardner, T. A., Paterson, R. F. & Stevens, L. H., Sep 2002, In : Journal of Urology. 168, 3, p. 941-944 4 p.

Research output: Contribution to journalArticle

29 Scopus citations

Novel prostate-specific promoter derived from PSA and PSMA enhancers

Lee, S. J., Kim, H. S., Yu, R., Lee, K. R., Gardner, T. A., Jung, C., Jeng, M. H., Yeung, F., Cheng, L. & Kao, C., Sep 1 2002, In : Molecular Therapy. 6, 3, p. 415-421 7 p.

Research output: Contribution to journalArticle

69 Scopus citations

One versus two proficient laparoscopic surgeons for laparoscopic live donor nephrectomy

Siqueira, T. M., Gardner, T. A., Kuo, R. L., Paterson, R. F., Stevens, L. H., Lingeman, J. E. & Shalhav, A. L., Sep 2002, In : Urology. 60, 3, p. 406-409 4 p.

Research output: Contribution to journalArticle

13 Scopus citations

Prostate cancer gene therapy: Past experiences and future promise

Gardner, T. A., Sloan, J., Raikwar, S. P. & Kao, C., Nov 28 2002, In : Cancer and Metastasis Reviews. 21, 2, p. 137-145 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Relative promoter strengths in four human prostate cancer cell lines evaluated by particle bombardment-mediated gene transfer

Zhang, S., Gu, J., Yang, N. S., Kao, C., Gardner, T. A., Eble, J. N. & Cheng, L., Jun 1 2002, In : Prostate. 51, 4, p. 286-292 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Transperitoneal laparoscopic renal surgery using blunt 12-mm trocar without fascial closure

Shalhav, A. L., Barret, E., Lifshitz, D. A., Stevens, L. H., Gardner, T. A. & Lingeman, J. E., Feb 2002, In : Journal of Endourology. 16, 1, p. 43-46 4 p.

Research output: Contribution to journalArticle

27 Scopus citations

Transrectal high-intensity focused ultrasound for treatment of patients with stage T1b-2n0m0 localized prostate cancer: A preliminary report

Uchida, T., Sanghvi, N. T., Gardner, T. A., Koch, M. O., Ishii, D., Minei, S., Satoh, T., Hyodo, T., Irie, A. & Baba, S., Mar 13 2002, In : Urology. 59, 3, p. 394-398 5 p.

Research output: Contribution to journalArticle

170 Scopus citations
2001
20 Scopus citations

A conditional replication-competent adenoviral vector, AD-OC-E1a, to cotarget prostate cancer and bone stroma in an experimental model of androgen-independent prostate cancer bone metastasis

Matsubara, S., Wada, Y., Gardner, T. A., Egawa, M., Par, M. S., Hsieh, C. L., Zhau, H. E., Kao, C., Kamidono, S., Gillenwater, J. Y. & Chung, L. W. K., Aug 15 2001, In : Cancer Research. 61, 16, p. 6012-6019 8 p.

Research output: Contribution to journalArticle

134 Scopus citations

Drug-resistant human bladder-cancer cells are more sensitive to adenovirus-mediated wild-type p53 gene therapy compared to drug-sensitive cells

Shirakawa, T., Sasaki, R., Gardner, T. A., Kao, C., Zhang, Z. J., Sugimura, K., Matsuo, M., Kamidono, S. & Gotoh, A., Oct 15 2001, In : International Journal of Cancer. 94, 2, p. 282-289 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Serum-free recombinant production of adenovirus using a hollow fiber capillary system

Gardner, T. A., Ko, S. C., Yang, L., Cadwell, J. J. S., Chung, L. W. K. & Kao, C., 2001, In : BioTechniques. 30, 2, p. 422-427 6 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations
2000

Osteocalcin-directed gene therapy for prostate-cancer bone metastasis

Koeneman, K. S., Kao, C., Ko, S. C., Yang, L., Wada, Y., Kallmes, D. F., Gillenwater, J. Y., Zhau, H. E., Cluing, L. W. K. & Gardner, T. A., Jan 1 2000, In : World Journal of Urology. 18, 2, p. 102-110 9 p.

Research output: Contribution to journalArticle

109 Scopus citations

P53 Adenoviral vector (Ad-CMV-p53) induced prostatic growth inhibition of primary cultures of human prostate and an experimental rat model

Shirakawa, T., Gotoh, A., Gardner, T. A., Kao, C., Zhang, Z. J., Matsubara, S., Wada, Y., Hinata, N., Fujisawa, M., Hanioka, K., Matsuo, M. & Kamidono, S., 2000, In : Journal of Gene Medicine. 2, 6, p. 426-432 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Surgical postoperative factors affecting length of hospital stay after radical prostatectomy

Gardner, T. A., Bissonette, E. A., Petroni, G. R., McClain, R., Sokoloff, M. H. & Theodorescu, D., Jul 15 2000, In : Cancer. 89, 2, p. 424-430 7 p.

Research output: Contribution to journalArticle

43 Scopus citations

Tissue-specific promoters in gene therapy for the treatment of prostate cancer

Shirakawa, T., Gotoh, A., Wada, Y., Kamidono, S., Ko, S. C., Kao, C., Gardner, T. A. & Chung, L. W. K., Jan 1 2000, In : Molecular Urology. 4, 2, p. 73-82 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Transurethral high intensity focused ultrasound: Catheter based prototypes and experimental results

Seip, R., Biswas, M., Kuznetsov, M., Sanghvi, N. T., Gardner, T. A. & Dabhoiwala, N. F., Jan 1 2000, In : Proceedings of the IEEE Ultrasonics Symposium. 2, p. 1413-1416 4 p.

Research output: Contribution to journalArticle

3 Scopus citations
1999

Cytotoxicity of adenoviral-mediated cytosine deaminase plus 5- fluorocytosine gene therapy is superior to thymidine kinase plus acyclovir in a human renal cell carcinoma model

Shirakawa, T., Gardner, T. A., Ko, S. C., Bander, N., Woo, S., Gotoh, A., Kamidono, S., Chung, L. W. K. & Kao, C., Sep 1999, In : Journal of Urology. 162, 3 I, p. 949-954 6 p.

Research output: Contribution to journalArticle

31 Scopus citations
1998

Development of prostate-specific antigen promoter-based gene therapy for androgen-independent human prostate cancer

Gotoh, A., Ko, S. C., Shirakawa, T., Cheon, J., Kao, C., Miyamoto, T., Gardner, T. A., Ho, L. J., Cleutjens, C. B. J., Trapman, J., Graham, F. L. & Chung, L. W. K., Jul 1998, In : Journal of Urology. 160, 1, p. 220-229 10 p.

Research output: Contribution to journalArticle

101 Scopus citations

Diagnostic flexible peritoneoscopy: Assessment of the contralateral internal inguinal ring during unilateral herniorrhaphy

Gardner, T. A., Ostad, M. & Mininberg, D. T., Oct 1998, In : Journal of Pediatric Surgery. 33, 10, p. 1486-1489 4 p.

Research output: Contribution to journalArticle

11 Scopus citations

Flexible transinguinal laparoscopy to assess the contralateral ring in pediatric inguinal hernias

Pavlovich, C. P., Gmyrek, G. A., Gardner, T. A., Poppas, D. P. & Mininberg, D. T., Nov 2 1998, In : Techniques in urology. 4, 3, p. 141-144 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

In vivo suppression of osteosarcoma pulmonary metastasis with intravenous osteocalcin promoter-based toxic gene therapy

Shirakawa, T., Ko, S. C., Gardner, T. A., Cheon, J., Miyamoto, T., Gotoh, A., Chung, L. W. K. & Kao, C., Dec 1 1998, In : Cancer gene therapy. 5, 5, p. 274-280 7 p.

Research output: Contribution to journalArticle

46 Scopus citations

Microfocal prostate cancer: Biopsy cancer volume does not predict actual tumour volume

Gardner, T. A., Lemer, M. L., Schlegel, P. N., Waldbaum, R. S., Darracott Vaughan, E. & Steckel, J., Jul 13 1998, In : British Journal of Urology. 81, 6, p. 839-843 5 p.

Research output: Contribution to journalArticle

28 Scopus citations