Thomas Gardner

  • 3381 Citations
  • 31 h-Index
1977 …2018
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Publications 1994 2018

  • 3381 Citations
  • 31 h-Index
  • 111 Article
  • 7 Conference contribution
  • 2 Chapter
  • 1 Comment/debate
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Article
2005
56 Citations (Scopus)

Gene therapy for prostate cancer by controlling adenovirus E1a and E4 gene expression with PSES enhancer

Li, X., Zhang, Y. P., Kim, H. S., Bae, K. H., Stantz, K. M., Lee, S. J., Jung, C., Jiménez, J. A., Gardner, T., Jeng, M. H. & Kao, C., Mar 1 2005, In : Cancer Research. 65, 5, p. 1941-1951 11 p.

Research output: Contribution to journalArticle

Adenoviridae
Genetic Therapy
Prostatic Neoplasms
Prostate-Specific Antigen
Gene Expression
49 Citations (Scopus)

HOXB13 is downregulated in colorectal cancer to confer TCF4-mediated transactivation

Jung, C., Kim, R. S., Zhang, H., Lee, S. J., Sheng, H., Loehrer, P., Gardner, T., Jeng, M. H. & Kao, C., Jun 20 2005, In : British Journal of Cancer. 92, 12, p. 2233-2239 7 p.

Research output: Contribution to journalArticle

Transcription Factor 7-Like 2 Protein
Transcriptional Activation
Colorectal Neoplasms
Down-Regulation
Catenins
23 Citations (Scopus)

Is it necessary to separate clinical stage T1c from T2 prostate adenocarcinoma?

Armatys, S. A., Koch, M., Bihrle, R., Gardner, T. & Cheng, L., Oct 2005, In : BJU International. 96, 6, p. 777-780 4 p.

Research output: Contribution to journalArticle

Prostate
Adenocarcinoma
Neoplasms
Neoplasm Grading
Prostatectomy
16 Citations (Scopus)

Prostate cancer therapy with high-intensity focused ultrasound

Gardner, T. & Koch, M., Dec 2005, In : Clinical Genitourinary Cancer. 4, 3, p. 187-192 6 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Clinical Trials
Prostate
Technology
Therapeutics
2 Citations (Scopus)

Pulmonary sequestration presenting as retroperitoneal cyst: Case report

Armatys, S. A., Cheng, L., Gardner, T. & Sundaram, C., Oct 2005, In : Journal of Endourology. 19, 8, p. 997-999 3 p.

Research output: Contribution to journalArticle

Bronchopulmonary Sequestration
Cysts
Surgical Blood Loss
Flank Pain
Pneumothorax
16 Citations (Scopus)
Positron emission tomography
Thymidine Kinase
Simplexvirus
Reporter Genes
Viruses
82 Citations (Scopus)
Prostatectomy
Neoplasm Grading
Neoplasms
Prostatic Neoplasms
Prostate-Specific Antigen
3 Citations (Scopus)

Thermal-based treatment options for localized prostate cancer

Koch, M. & Gardner, T., Sep 2005, In : Current Treatment Options in Oncology. 6, 5, p. 379-387 9 p.

Research output: Contribution to journalArticle

Prostate
Prostatic Neoplasms
Hot Temperature
Radiation
Morbidity
13 Citations (Scopus)

Transcriptional targeting modalities in breast cancer gene therapy using adenovirus vectors controlled by α-lactalbumin promoter

Li, X., Zhang, J., Gao, H., Vieth, E., Bae, K. H., Zhang, Y. P., Lee, S. J., Raikwar, S., Gardner, T., Hutchins, G., VanderPutten, D., Kao, C. & Jeng, M. H., Dec 2005, In : Molecular Cancer Therapeutics. 4, 12, p. 1850-1859 10 p.

Research output: Contribution to journalArticle

Lactalbumin
Neoplasm Genes
Adenoviridae
Genetic Therapy
Breast Neoplasms
10 Citations (Scopus)

Utility of the fourth arm to facilitate robot-assisted laparoscopic radical prostatectomy

Sundaram, C., Koch, M., Gardner, T. & Bernie, J. E., Jan 2005, In : BJU International. 95, 1, p. 183-186 4 p.

Research output: Contribution to journalArticle

Laparoscopes
Equipment Design
Robotics
Prostatectomy
Laparoscopy
2004
53 Citations (Scopus)

[11C]Choline as a PET biomarker for assessment of prostate cancer tumor models

Zheng, Q-H., Gardner, T., Raikwar, S., Kao, C., Stone, K. L., Martinez, T. D., Mock, B. H., Fei, X., Wang, J. Q. & Hutchins, G., Jun 1 2004, In : Bioorganic and Medicinal Chemistry. 12, 11, p. 2887-2893 7 p.

Research output: Contribution to journalArticle

Positron emission tomography
Biomarkers
Choline
Positron-Emission Tomography
Tumors
128 Citations (Scopus)

Aberrant expression of CARM1, a transcriptional coactivator of androgen receptor, in the development of prostate carcinoma and androgen-independent status

Hong, H., Kao, C., Jeng, M. H., Eble, J., Koch, M., Gardner, T., Zhang, S., Li, L., Pan, C. X., Hu, Z., MacLennan, G. T. & Cheng, L., Jul 1 2004, In : Cancer. 101, 1, p. 83-89 7 p.

Research output: Contribution to journalArticle

Androgen Receptors
Androgens
Prostate
Carcinoma
Prostatic Intraepithelial Neoplasia
25 Citations (Scopus)

Allelic Loss of the Active X Chromosome during Bladder Carcinogenesis

Cheng, L., MacLennan, G. T., Pan, C. X., Jones, T. D., Moore, C. R., Zhang, S., Gu, J., Patel, N. B., Kao, C. & Gardner, T., Feb 2004, In : Archives of Pathology and Laboratory Medicine. 128, 2, p. 187-190 4 p.

Research output: Contribution to journalArticle

Loss of Heterozygosity
X Chromosome
X Chromosome Inactivation
Carcinogenesis
Urinary Bladder
32 Citations (Scopus)
Vascular Endothelial Growth Factor A
Androgens
Prostatic Neoplasms
Castration
Growth
9 Citations (Scopus)

An Improved Total Synthesis of PET HSV-tk Gene Expression Imaging Agent 9-[(3-[18F]Fluoro-1-hydroxy-2-propoxy)methyl]guanine ([ 18F]FHPG)

Wang, J. Q., Zheng, Q-H., Fei, X., Liu, X., Gardner, T., Kao, C., Raikwar, S. P., Glick-Wilson, B. E., Sullivan, M. L., Mock, B. H. & Hutchins, G., 2004, In : Synthetic Communications. 34, 5, p. 917-932 16 p.

Research output: Contribution to journalArticle

Guanine
Gene expression
Imaging techniques
2-Propanol
Silicon Dioxide
9 Citations (Scopus)

An Improved Total Synthesis of PET HSV-tk Gene Reporter Probe 9-(4-[ 18F]Fluoro-3-hydroxymethylbutyl)guanine ([18F]FHBG)

Zheng, Q-H., Wang, J. Q., Liu, X., Fei, X., Mock, B. H., Glick-Wilson, B. E., Sullivan, M. L., Raikwar, S. P., Gardner, T., Kao, C. & Hutchins, G., 2004, In : Synthetic Communications. 34, 4, p. 689-704 16 p.

Research output: Contribution to journalArticle

Guanine
Genes
Silicon Dioxide
Purification
Substitution reactions
38 Citations (Scopus)

Cotargeting tumor and stroma in a novel chimeric tumor model involving the growth of both human prostate cancer and bone stromal cells

Hsieh, C. L., Gardner, T., Miao, L., Balian, G. & Chung, L. W. K., Feb 2004, In : Cancer Gene Therapy. 11, 2, p. 148-155 8 p.

Research output: Contribution to journalArticle

Bone Neoplasms
Stromal Cells
Prostatic Neoplasms
Growth
Neoplasms
3 Citations (Scopus)

Development of human chorionic gonadotropin subunit-beta promoter-based toxic gene therapy for testicular cancer.

Shirakawa, T., Gotoh, A., Zhang, Z., Kao, C., Chung, L. W. K. & Gardner, T., Mar 2004, In : Urology. 63, 3, p. 613-618 6 p.

Research output: Contribution to journalArticle

Chorionic Gonadotropin, beta Subunit, Human
Poisons
Testicular Neoplasms
Chorionic Gonadotropin
Genetic Therapy
146 Citations (Scopus)

Nuclear factor-κB is constitutively activated in prostate cancer in vitro and is overexpressed in prostatic intraepithelial neoplasia and adenocarcinoma of the prostate

Sweeney, C., Li, L., Shanmugam, R., Bhat-Nakshatri, P., Jayaprakasan, V., Baldridge, L. A., Gardner, T., Smith, M., Nakshatri, H. & Cheng, L., Aug 15 2004, In : Clinical Cancer Research. 10, 16, p. 5501-5507 7 p.

Research output: Contribution to journalArticle

Prostatic Intraepithelial Neoplasia
Prostate
Prostatic Neoplasms
Staining and Labeling
Prostatectomy
15 Citations (Scopus)

Targeting prostate cancer with conditionally replicative adenovirus using PSMA enhancer

Lee, S. J., Zhang, Y., Lee, S. D., Jung, C., Li, X., Kim, H. S., Bae, K. H., Jeng, M. H., Kao, C. & Gardner, T., Dec 2004, In : Molecular Therapy. 10, 6, p. 1051-1058 8 p.

Research output: Contribution to journalArticle

Adenoviridae
Prostatic Neoplasms
Androgens
Prostate
Hormones
148 Citations (Scopus)

Transitional cell carcinoma of the bladder following augmentation cystoplasty for the neuropathic bladder

Soergel, T. M., Cain, M. P., Misseri, R., Gardner, T., Koch, M., Rink, R. C., Strand, W., Austin, P., Shortliffe, L., Diamond, D. & Park, J., Oct 2004, In : Journal of Urology. 172, 4 II, p. 1649-1652 4 p.

Research output: Contribution to journalArticle

Neurogenic Urinary Bladder
Transitional Cell Carcinoma
Urinary Bladder
Neoplasms
Databases
11 Citations (Scopus)

Tumor-specific gene therapy for uterine cervical cancer using MN/CA9-directed replication-competent adenovirus

Lim, H. Y., Ahn, M., Chung, H. C., Gardner, T., Kao, C., Lee, S. J. & Kim, S. J., Aug 2004, In : Cancer Gene Therapy. 11, 8, p. 532-538 7 p.

Research output: Contribution to journalArticle

Adenoviridae
Uterine Cervical Neoplasms
Genetic Therapy
Neoplasms
Growth
2003
39 Citations (Scopus)
Prostatectomy
Adipose Tissue
Prostate
Carcinoma
Lymph Node Excision
22 Citations (Scopus)
Prostate-Specific Antigen
Prostatectomy
Disease-Free Survival
Prostatic Neoplasms
Recurrence
140 Citations (Scopus)

Biology of Childhood Osteogenic Sarcoma and Potential Targets for Therapeutic Development: Meeting Summary

Gorlick, R., Anderson, P., Andrulis, I., Arndt, C., Beardsley, G. P., Bernstein, M., Bridge, J., Cheung, N. K., Dome, J. S., Ebb, D., Gardner, T., Gebhardt, M., Grier, H., Hansen, M., Healey, J., Helman, L., Hock, J., Houghton, J., Houghton, P., Huvos, A. & 19 others, Khanna, C., Kieran, M., Kleinerman, E., Ladanyi, M., Lau, C., Malkin, D., Marina, N., Meltzer, P., Meyers, P., Schofield, D., Schwartz, C., Smith, M. A., Toretsky, J., Tsokos, M., Wexler, L., Wigginton, J., Withrow, S., Schoenfeldt, M. & Anderson, B., Nov 15 2003, In : Clinical Cancer Research. 9, 15, p. 5442-5453 12 p.

Research output: Contribution to journalArticle

Osteosarcoma
Bone Neoplasms
National Cancer Institute (U.S.)
Program Evaluation
Therapeutics
45 Citations (Scopus)

Early catheter removal after radical retropubic prostatectomy: Long-term followup

Koch, M., Nayee, A. H., Sloan, J., Gardner, T., Wahle, G. R., Bihrle, R. & Foster, R., Jun 1 2003, In : Journal of Urology. 169, 6, p. 2170-2172 3 p.

Research output: Contribution to journalArticle

Prostatectomy
Catheters
Prostatic Neoplasms
Indwelling Catheters
Drainage
92 Citations (Scopus)

High-Level Expression of EphA2 Receptor Tyrosine Kinase in Prostatic Intraepithelial Neoplasia

Zeng, G., Hu, Z., Kinch, M. S., Pan, C. X., Flockhart, D. A., Kao, C., Gardner, T., Zhang, S., Li, L., Baldridge, L. A., Koch, M., Ulbright, T., Eble, J. & Cheng, L., Dec 2003, In : American Journal of Pathology. 163, 6, p. 2271-2276 6 p.

Research output: Contribution to journalArticle

EphA2 Receptor
Prostatic Intraepithelial Neoplasia
Adenocarcinoma
Epithelium
Carcinoma
44 Citations (Scopus)

Laparoscopic partial kidney ablation with high intensity focused ultrasound

Paterson, R. F., Barret, E., Siqueira, T. M., Gardner, T., Tavakkoli, J., Rao, V. V., Sanghvi, N. T., Cheng, L. & Shalhav, A. L., Jan 1 2003, In : Journal of Urology. 169, 1, p. 347-351 5 p.

Research output: Contribution to journalArticle

High-Intensity Focused Ultrasound Ablation
Kidney
Ultrasonography
Urinary Catheters
Kidney Pelvis
18 Citations (Scopus)

Nephrectomy for metastatic renal cell carcinoma: Indiana University experience

Mosharafa, A., Koch, M., Shalhav, A., Gardner, T., Logan, T., Bihrle, R. & Foster, R., Oct 1 2003, In : Urology. 62, 4, p. 636-640 5 p.

Research output: Contribution to journalArticle

Nephrectomy
Renal Cell Carcinoma
Immunotherapy
Morbidity
Intraoperative Complications
47 Citations (Scopus)

New targets for therapy in prostate cancer: Modulation of stromal-epithelial interactions

Chung, L. W. K., Hsieh, C. L., Law, A., Sung, S. Y., Gardner, T., Egawa, M., Matsubara, S. & Zhau, H. E., Nov 2003, In : Urology. 62, 5 SUPPL. 1, p. 44-54 11 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Prostate
Neoplasms
Osteocalcin
Therapeutics
22 Citations (Scopus)

NFATc1 with AP-3 site binding specificity mediates gene expression of prostate-specific-membrane-antigen.

Lee, S. J., Lee, K., Yang, X., Jung, C., Gardner, T., Kim, H. S., Jeng, M. H. & Kao, C., Jul 18 2003, In : Journal of Molecular Biology. 330, 4, p. 749-760 12 p.

Research output: Contribution to journalArticle

Binding Sites
Gene Expression
Transcription Factor AP-1
Prostate
Protein Isoforms
101 Citations (Scopus)

Phase I dose escalation clinical trial of adenovirus vector carrying osteocalcin promoter-driven herpes simplex virus thymidine kinase in localized and metastatic hormone-refractory prostate cancer

Kubo, H., Gardner, T., Wada, Y., Koeneman, K. S., Gotoh, A., Yang, L., Kao, C., Lim, S. D., Amin, M. B., Yang, H., Black, M. E., Matsubara, S., Nakagawa, M., Gillenwater, J. Y., Zhau, H. E. & Chung, L. W. K., Feb 10 2003, In : Human Gene Therapy. 14, 3, p. 227-241 15 p.

Research output: Contribution to journalArticle

Thymidine Kinase
Osteocalcin
Simplexvirus
Adenoviridae
Prostatic Neoplasms
2002
7 Citations (Scopus)

Adenovirus-mediated suicide-gene therapy in an orthotopic murine bladder tumor model

Cheon, J., Moon, D. G., Cho, H. Y., Park, H. S., Kim, J. J., Gardner, T. & Kao, C., 2002, In : International Journal of Urology. 9, 5, p. 261-267 7 p.

Research output: Contribution to journalArticle

Rous sarcoma virus
Ganciclovir
Urinary Bladder Neoplasms
Adenoviridae
Genetic Therapy
30 Citations (Scopus)

Fas and Fas ligand expression is elevated in prostatic intraepithelial neoplasia and prostatic adenocarcinoma

Jiang, J., Ulbright, T., Zhang, S., Eckert, G. J., Kao, C., Gardner, T., Koch, M., Eble, J. & Cheng, L., Jul 15 2002, In : Cancer. 95, 2, p. 296-300 5 p.

Research output: Contribution to journalArticle

Prostatic Intraepithelial Neoplasia
Fas Ligand Protein
Adenocarcinoma
Prostate
Staining and Labeling
8 Citations (Scopus)

Fas-Fas ligand signaling pathway mediates an interleukin-12-induced rejection of a murine prostate tumor system

Zhang, S., Zeng, G., Kao, C., Gardner, T., Sweeney, C., Yang, N. S., Eble, J. & Cheng, L., Sep 15 2002, In : Prostate. 53, 1, p. 69-76 8 p.

Research output: Contribution to journalArticle

Fas Ligand Protein
Interleukin-12
Prostate
Neoplasms
Apoptosis
89 Citations (Scopus)

Major complications in 213 laparoscopic nephrectomy cases: The Indianapolis experience

Siqueira, T. M., Kuo, R. L., Gardner, T., Paterson, R. F., Stevens, L. H., Lingeman, J. E., Koch, M. & Shalhav, A. L., Oct 2002, In : Journal of Urology. 168, 4 I, p. 1361-1365 5 p.

Research output: Contribution to journalArticle

Nephrectomy
Conversion to Open Surgery
Emergencies
Intraoperative Complications
Tissue Donors
29 Citations (Scopus)

Manual specimen retrieval without a pneumoperitoneum preserving device for laparoscopic live donor nephrectomy

Shalhav, A. L., Siqueira, T. M., Gardner, T., Paterson, R. F. & Stevens, L. H., Sep 2002, In : Journal of Urology. 168, 3, p. 941-944 4 p.

Research output: Contribution to journalArticle

Warm Ischemia
Pneumoperitoneum
Nephrectomy
Equipment and Supplies
Hand
69 Citations (Scopus)

Novel prostate-specific promoter derived from PSA and PSMA enhancers

Lee, S. J., Kim, H. S., Yu, R., Lee, K., Gardner, T., Jung, C., Jeng, M. H., Yeung, F., Cheng, L. & Kao, C., Sep 1 2002, In : Molecular Therapy. 6, 3, p. 415-421 7 p.

Research output: Contribution to journalArticle

Prostate-Specific Antigen
Prostate
Prostatic Neoplasms
Luciferases
Cell Line
13 Citations (Scopus)

One versus two proficient laparoscopic surgeons for laparoscopic live donor nephrectomy

Siqueira, T. M., Gardner, T., Kuo, R. L., Paterson, R. F., Stevens, L. H., Lingeman, J. E. & Shalhav, A. L., 2002, In : Urology. 60, 3, p. 406-409 4 p.

Research output: Contribution to journalArticle

Nephrectomy
Tissue Donors
Learning Curve
Operative Time
Surgeons
6 Citations (Scopus)

Prostate cancer gene therapy: Past experiences and future promise

Gardner, T., Sloan, J., Raikwar, S. P. & Kao, C., 2002, In : Cancer and Metastasis Reviews. 21, 2, p. 137-145 9 p.

Research output: Contribution to journalArticle

Neoplasm Genes
Genetic Therapy
Prostatic Neoplasms
Genes
Research Personnel
9 Citations (Scopus)

Relative promoter strengths in four human prostate cancer cell lines evaluated by particle bombardment-mediated gene transfer

Zhang, S., Gu, J., Yang, N. S., Kao, C., Gardner, T., Eble, J. & Cheng, L., Jun 1 2002, In : Prostate. 51, 4, p. 286-292 7 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Cell Line
Genes
Galactosidases
Transfection
27 Citations (Scopus)

Transperitoneal laparoscopic renal surgery using blunt 12-mm trocar without fascial closure

Shalhav, A. L., Barret, E., Lifshitz, D. A., Stevens, L. H., Gardner, T. & Lingeman, J. E., 2002, In : Journal of Endourology. 16, 1, p. 43-46 4 p.

Research output: Contribution to journalArticle

Surgical Instruments
Laparoscopy
Kidney
Abdominal Wall
Muscles
169 Citations (Scopus)

Transrectal high-intensity focused ultrasound for treatment of patients with stage T1b-2n0m0 localized prostate cancer: A preliminary report

Uchida, T., Sanghvi, N. T., Gardner, T., Koch, M., Ishii, D., Minei, S., Satoh, T., Hyodo, T., Irie, A. & Baba, S., 2002, In : Urology. 59, 3, p. 394-398 5 p.

Research output: Contribution to journalArticle

Transrectal High-Intensity Focused Ultrasound
Prostatic Neoplasms
Therapeutics
Prostate-Specific Antigen
Prostate
2001
20 Citations (Scopus)
Prostate-Specific Antigen
Prostatectomy
Recurrence
133 Citations (Scopus)

A conditional replication-competent adenoviral vector, AD-OC-E1a, to cotarget prostate cancer and bone stroma in an experimental model of androgen-independent prostate cancer bone metastasis

Matsubara, S., Wada, Y., Gardner, T., Egawa, M., Par, M. S., Hsieh, C. L., Zhau, H. E., Kao, C., Kamidono, S., Gillenwater, J. Y. & Chung, L. W. K., Aug 15 2001, In : Cancer Research. 61, 16, p. 6012-6019 8 p.

Research output: Contribution to journalArticle

Bone Neoplasms
Osteocalcin
Androgens
Prostatic Neoplasms
Theoretical Models
21 Citations (Scopus)

Drug-resistant human bladder-cancer cells are more sensitive to adenovirus-mediated wild-type p53 gene therapy compared to drug-sensitive cells

Shirakawa, T., Sasaki, R., Gardner, T., Kao, C., Zhang, Z. J., Sugimura, K., Matsuo, M., Kamidono, S. & Gotoh, A., Oct 15 2001, In : International Journal of Cancer. 94, 2, p. 282-289 8 p.

Research output: Contribution to journalArticle

p53 Genes
Urinary Bladder Neoplasms
Adenoviridae
Genetic Therapy
Cell Line
11 Citations (Scopus)

Serum-free recombinant production of adenovirus using a hollow fiber capillary system

Gardner, T., Ko, S. C., Yang, L., Cadwell, J. J. S., Chung, L. W. K. & Kao, C., 2001, In : BioTechniques. 30, 2, p. 422-427 6 p.

Research output: Contribution to journalArticle

Adenoviridae
Cell culture
Fibers
Serum
Cell Culture Techniques
2000
109 Citations (Scopus)

Osteocalcin-directed gene therapy for prostate-cancer bone metastasis

Koeneman, K. S., Kao, C., Ko, S. C., Yang, L., Wada, Y., Kallmes, D. F., Gillenwater, J. Y., Zhau, H. E., Cluing, L. W. K. & Gardner, T., 2000, In : World Journal of Urology. 18, 2, p. 102-110 9 p.

Research output: Contribution to journalArticle

Bone Neoplasms
Osteocalcin
Genetic Therapy
Prostatic Neoplasms
Neoplasm Metastasis
4 Citations (Scopus)

P53 Adenoviral vector (Ad-CMV-p53) induced prostatic growth inhibition of primary cultures of human prostate and an experimental rat model

Shirakawa, T., Gotoh, A., Gardner, T., Kao, C., Zhang, Z. J., Matsubara, S., Wada, Y., Hinata, N., Fujisawa, M., Hanioka, K., Matsuo, M. & Kamidono, S., Nov 2000, In : Journal of Gene Medicine. 2, 6, p. 426-432 7 p.

Research output: Contribution to journalArticle

Prostatic Hyperplasia
Prostate
Theoretical Models
Growth
Apoptosis
43 Citations (Scopus)

Surgical postoperative factors affecting length of hospital stay after radical prostatectomy

Gardner, T., Bissonette, E. A., Petroni, G. R., McClain, R., Sokoloff, M. H. & Theodorescu, D., Jul 15 2000, In : Cancer. 89, 2, p. 424-430 7 p.

Research output: Contribution to journalArticle

Prostatectomy
Length of Stay
Costs and Cost Analysis
Prostate
Carcinoma