Timothy Sutton

  • 2673 Citations
  • 22 h-Index
1988 …2020

Research output per year

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Publications

Article

Acute and chronic microvascular alterations in a mouse model of ischemic acute kidney injury

Hörbelt, M., Lee, S. Y., Mang, H. E., Knipe, N. L., Sado, Y., Kribben, A. & Sutton, T. A., Sep 1 2007, In : American Journal of Physiology - Renal Physiology. 293, 3, p. F688-F695

Research output: Contribution to journalArticle

113 Scopus citations

Alteration of microvascular permeability in acute kidney injury

Sutton, T. A., Jan 1 2009, In : Microvascular Research. 77, 1, p. 4-7 4 p.

Research output: Contribution to journalArticle

64 Scopus citations

Application of laser microdissection to uncover regional transcriptomics in human kidney tissue

Kidney Precision Medicine Project, 2020, In : Journal of Visualized Experiments. 2020, 160, p. 1-9 9 p., e61371.

Research output: Contribution to journalArticle

Endothelial HIF-2 mediates protection and recovery from ischemic kidney injury

Kapitsinou, P. P., Sano, H., Michael, M., Kobayashi, H., Davidoff, O., Bian, A., Yao, B., Zhang, M. Z., Harris, R. C., Duffy, K. J., Erickson-Miller, C. L., Sutton, T. A. & Haase, V. H., Jun 2 2014, In : Journal of Clinical Investigation. 124, 6, p. 2396-2409 14 p.

Research output: Contribution to journalArticle

83 Scopus citations

Endothelial injury and dysfunction: Role in the extension phase of acute renal failure

Molitoris, B. A. & Sutton, T. A., Aug 2004, In : Kidney international. 66, 2, p. 496-499 4 p.

Research output: Contribution to journalArticle

258 Scopus citations

Endothelial injury and dysfunction in ischemic acute renal failure

Molitoris, B. A., Sandoval, R. & Sutton, T. A., May 23 2002, In : Critical care medicine. 30, 5 SUPPL., p. S235-S240

Research output: Contribution to journalArticle

93 Scopus citations

Endothelial STAT3 Modulates Protective Mechanisms in a Mouse Ischemia-Reperfusion Model of Acute Kidney Injury

Dube, S., Matam, T., Yen, J., Mang, H. E., Dagher, P. C., Hato, T. & Sutton, T. A., Jan 1 2017, In : Journal of Immunology Research. 2017, 4609502.

Research output: Contribution to journalArticle

10 Scopus citations

Functional studies in living animals using multiphoton microscopy

Dunn, K. W. & Sutton, T. A., Sep 11 2012, In : ILAR Journal. 53, 1, p. 66-77 12 p.

Research output: Contribution to journalArticle

Impaired endothelial proliferation and mesenchymal transition contribute to vascular rarefaction following acute kidney injury

Basile, D. P., Friedrich, J. L., Spahic, J., Knipe, N., Mang, H., Leonard, E. C., Changizi-Ashtiyani, S., Bacallao, R. L., Molitoris, B. A. & Sutton, T. A., Mar 1 2011, In : American Journal of Physiology - Renal Physiology. 300, 3, p. F721-F733

Research output: Contribution to journalArticle

185 Scopus citations

Inhibition of toll-like receptor 4 signaling mitigates microvascular loss but not fibrosis in a model of ischemic acute kidney injury

Dagher, P. C., Hato, T., Mang, H. E., Plotkin, Z., Richardson, Q. V., Massad, M., Mai, E., Kuehl, S. E., Graham, P., Kumar, R. & Sutton, T. A., May 2016, In : International journal of molecular sciences. 17, 5, 647.

Research output: Contribution to journalArticle

8 Scopus citations

Injury of the renal microvascular endothelium alters barrier function after ischemia

Sutton, T. A., Mang, H. E., Campos, S. B., Sandoval, R. M., Yoder, M. C. & Molitoris, B. A., Aug 1 2003, In : American Journal of Physiology - Renal Physiology. 285, 2 54-2, p. F191-F198

Research output: Contribution to journalArticle

241 Scopus citations

Live-animal imaging of renal function by multiphoton Microscopy

Dunn, K. W., Sutton, T. A. & Sandoval, R. M., Dec 1 2012, In : Current Protocols in Cytometry. SUPPL.62, p. 12.9

Research output: Contribution to journalArticle

13 Scopus citations

Live-Animal Imaging of Renal Function by Multiphoton Microscopy

Dunn, K. W., Sutton, T. A. & Sandoval, R. M., Jan 1 2018, In : Current Protocols in Cytometry. 83, 1, p. 12.9.1-12.9.25

Research output: Contribution to journalArticle

5 Scopus citations
9 Scopus citations

Microvascular endothelial injury and dysfunction during ischemic acute renal failure

Sutton, T. A., Fisher, C. J. & Molitoris, B. A., Nov 2002, In : Kidney international. 62, 5, p. 1539-1549 11 p.

Research output: Contribution to journalArticle

399 Scopus citations

Minocycline inhibits apoptosis and inflammation in a rat model of ischemic renal injury

Kelly, K. J., Sutton, T. A., Weathered, N., Ray, N., Caldwell, E. J., Plotkin, Z. & Dagher, P. C., Oct 1 2004, In : American Journal of Physiology - Renal Physiology. 287, 4 56-4, p. F760-F766

Research output: Contribution to journalArticle

102 Scopus citations

Minocycline reduces renal microvascular leakage in a rat model of ischemic renal injury

Sutton, T. A., Kelly, K. J., Mang, H. E., Plotkin, Z., Sandoval, R. M. & Dagher, P. C., Jan 1 2005, In : American Journal of Physiology - Renal Physiology. 288, 1 57-1, p. F91-F97

Research output: Contribution to journalArticle

104 Scopus citations

MMP-9 gene deletion mitigates microvascular loss in a model of ischemic acute kidney injury

Lee, S. Y., Hörbelt, M., Mang, H. E., Knipe, N. L., Bacallao, R. L., Sado, Y. & Sutton, T. A., Jul 1 2011, In : American Journal of Physiology - Renal Physiology. 301, 1, p. F101-F109

Research output: Contribution to journalArticle

35 Scopus citations

Muc1 enhances the β-catenin protective pathway during ischemia-reperfusion injury

Al-Bataineh, M. M., Kinlough, C. L., Poland, P. A., Pastor-Soler, N. M., Sutton, T. A., Mang, H. E., Bastacky, S. I., Gendler, S. J., Madsen, C. S., Singh, S., Monga, S. P. & Hughey, R. P., Mar 15 2016, In : American Journal of Physiology - Renal Physiology. 310, 6, p. F569-F579

Research output: Contribution to journalArticle

17 Scopus citations

Muc1 is protective during kidney ischemia - Reperfusion injury

Pastor-Soler, N. M., Sutton, T. A., Mang, H. E., Kinlough, C. L., Gendler, S. J., Madsen, C. S., Bastacky, S. I., Ho, J., Al-Bataineh, M. M., Hallows, K. R., Singh, S., Monga, S. P., Kobayashi, H., Haase, V. H. & Hughey, R. P., Jun 15 2015, In : American Journal of Physiology - Renal Physiology. 308, 12, p. F1452-F1462

Research output: Contribution to journalArticle

22 Scopus citations

Novel application of complementary imaging techniques to examine in vivo glucose metabolism in the kidney

Hato, T., Friedman, A. N., Mang, H., Plotkin, Z., Dube, S., Hutchins, G. D., Territo, P. R., McCarthy, B. P., Riley, A. A., Pichumani, K., Malloy, C. R., Harris, R. A., Daghe, P. C. & Sutton, T. A., Apr 15 2016, In : American Journal of Physiology - Renal Physiology. 310, 8, p. F717-F725

Research output: Contribution to journalArticle

11 Scopus citations

Organic cation transport in the rat kidney in vivo visualized by time-resolved two-photon microscopy

Hörbelt, M., Wotzlaw, C., Sutton, T. A., Molitoris, B. A., Philipp, T., Kribben, A., Fandrey, J. & Pietruck, F., Aug 1 2007, In : Kidney international. 72, 4, p. 422-429 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

p53 is renoprotective after ischemic kidney injury by reducing inflammation

Sutton, T. A., Hato, T., Mai, E., Yoshimoto, M., Kuehl, S., Anderson, M., Mang, H., Plotkin, Z., Chan, R. J. & Dagher, P. C., Dec 28 2013, In : Journal of the American Society of Nephrology. 24, 1, p. 113-124 12 p.

Research output: Contribution to journalArticle

58 Scopus citations

p53 regulates renal expression of HIF-1α and pVHL under physiological conditions and after ischemia-reperfusion injury

Sutton, T. A., Wilkinson, J., Mang, H. E., Knipe, N. L., Plotkin, Z., Hosein, M., Zak, K., Wittenborn, J. & Dagher, P. C., Dec 1 2008, In : American Journal of Physiology - Renal Physiology. 295, 6, p. F1666-F1677

Research output: Contribution to journalArticle

32 Scopus citations

Pathophysiology of acute kidney injury

Basile, D. P., Anderson, M. D. & Sutton, T. A., Apr 2012, In : Comprehensive Physiology. 2, 2, p. 1303-1353 51 p.

Research output: Contribution to journalArticle

384 Scopus citations
38 Scopus citations

Phosphorylation of two sites on smooth muscle myosin. Effects on contraction of glycerinated vascular smooth muscle

Haeberle, J. R., Sutton, T. A. & Trockman, B. A., Jan 1 1988, In : Journal of Biological Chemistry. 263, 9, p. 4424-4429 6 p.

Research output: Contribution to journalArticle

29 Scopus citations
63 Scopus citations
13 Scopus citations

Rho-kinase regulates myosin II activation in MDCK cells during recovery after ATP depletion

Sutton, T. A., Mang, H. E. & Atkinson, S. J., Dec 19 2001, In : American Journal of Physiology - Renal Physiology. 281, 5 50-5, p. F810-F818

Research output: Contribution to journalArticle

26 Scopus citations

Soluble thrombomodulin reduces inflammation and prevents microalbuminuria induced by chronic endothelial activation in transgenic mice

Rajashekhar, G., Gupta, A., Marin, A., Friedrich, J., Willuweit, A., Berg, D. T., Cramer, M. S., Sandusky, G. E., Sutton, T. A., Basile, D. P., Grinnell, B. W. & Clauss, M., Mar 2012, In : American Journal of Physiology - Renal Physiology. 302, 6, p. F703-F712

Research output: Contribution to journalArticle

13 Scopus citations

The p53 inhibitor pifithrin-α can stimulate fibrosis in a rat model of ischemic acute kidney injury

Dagher, P. C., Mai, E. M., Hato, T., Lee, S. Y., Anderson, M. D., Karozos, S. C., Mang, H. E., Knipe, N. L., Plotkin, Z. & Sutton, T. A., Jan 2012, In : American Journal of Physiology - Renal Physiology. 302, 2, p. F284-F291

Research output: Contribution to journalArticle

38 Scopus citations
Comment/debate

Fueling the fire in acute kidney injury: Endothelial cells collect their Toll

Sutton, T. A. & Dagher, P. C., Feb 2011, In : Kidney international. 79, 3, p. 267-269 3 p.

Research output: Contribution to journalComment/debate

3 Scopus citations
Editorial
5 Scopus citations
Review article

Functional studies in living animals using multiphoton microscopy

Dunn, K. W. & Sutton, T. A., Jan 1 2008, In : ILAR Journal. 49, 1, p. 66-77 12 p.

Research output: Contribution to journalReview article

Open Access
28 Scopus citations

Imaging vascular pathology

Sutton, T. A., Hörbelt, M. & Sandoval, R. M., Mar 1 2006, In : Nephron - Physiology. 103, 2, p. p82-p85

Research output: Contribution to journalReview article

8 Scopus citations

Large-scale 3-dimensional quantitative imaging of tissues: state-of-the-art and translational implications

Winfree, S., Ferkowicz, M. J., Dagher, P. C., Kelly, K. J., Eadon, M. T., Sutton, T. A., Markel, T. A., Yoder, M. C., Dunn, K. W. & El-Achkar, T. M., Nov 2017, In : Translational Research. 189, p. 1-12 12 p.

Research output: Contribution to journalReview article

6 Scopus citations

Mechanisms of cellular injury in ischemic acute renal failure

Sutton, T. A. & Molitoris, B. A., Sep 30 1998, In : Seminars in nephrology. 18, 5, p. 490-497 8 p.

Research output: Contribution to journalReview article

137 Scopus citations

Novel roles for mucin 1 in the kidney

Al-Bataineh, M. M., Sutton, T. A. & Hughey, R. P., Sep 1 2017, In : Current Opinion in Nephrology and Hypertension. 26, 5, p. 384-391 8 p.

Research output: Contribution to journalReview article

5 Scopus citations

Quantitative large-scale three-dimensional imaging of human kidney biopsies: A bridge to precision medicine in kidney disease

Winfree, S., Dagher, P. C., Dunn, K. W., Eadon, M. T., Ferkowicz, M., Barwinska, D., Kelly, K. J., Sutton, T. A. & El-Achkar, T. M., Sep 1 2018, In : Nephron. 140, 2, p. 134-139 6 p.

Research output: Contribution to journalReview article

1 Scopus citations
Short survey

Combining microscopy with in vivo imaging

Sutton, T. A. & Dunn, K. W., Apr 15 2008, In : Genetic Engineering and Biotechnology News. 28, 8

Research output: Contribution to journalShort survey