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  • 12 Similar Profiles
Cytochrome P-450 CYP2D6 Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
Tamoxifen Medicine & Life Sciences
Pharmacogenetics Medicine & Life Sciences
Genotype Medicine & Life Sciences
Single Nucleotide Polymorphism Medicine & Life Sciences
Estrogen Receptors Medicine & Life Sciences
exemestane Medicine & Life Sciences

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NIH Grants 2009 2019

RNA Precursors
Protein Splicing
Messenger RNA
Paclitaxel
Computational Biology

Embedding Pharmacogenotyping in an Integrated Health System for the Underserved

Flockhart, D. A., Dexter, P. & Skaar, T.

National Institutes of Health

9/5/146/30/18

Project: Research projectResearch Project--Cooperative Agreements

Precision Medicine
Costs and Cost Analysis
Health
Vulnerable Populations
Pharmacogenetics

Regulation of drug metabolizing enzymes by miRNAs

Skaar, T.

National Institutes of Health

9/30/092/28/18

Project: Research projectResearch Project

Drug and Narcotic Control
MicroRNAs
Enzymes
Pharmaceutical Preparations
Cytochrome P-450 Enzyme System

Publications 1989 2018

  • 6385 Citations
  • 38 h-Index
  • 147 Article
  • 1 Review article

Allelic decomposition and exact genotyping of highly polymorphic and structurally variant genes

Numanagić, I., Malikić, S., Ford, M., Qin, X., Toji, L., Radovich, M., Skaar, T. C., Pratt, V. M., Berger, B., Scherer, S. & Sahinalp, S. C. Dec 1 2018 In : Nature Communications. 9, 1, 828

Research output: Contribution to journalArticle

sequencing
genes
decomposition
Genes
Gene Dosage

CYP2D6 and Endoxifen in Tamoxifen Therapy: A Tribute to David A. Flockhart

Skaar, T. C. & Desta, Z. Jan 1 2018 (Accepted/In press) In : Clinical Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP2D6
Tamoxifen
Guidelines
Clinical Pharmacology
Pharmacogenetics
1 Citations

Research Directions in the Clinical Implementation of Pharmacogenomics: An Overview of US Programs and Projects

Volpi, S. , Bult, C. J. , Chisholm, R. L. , Deverka, P. A. , Ginsburg, G. S. , Jacob, H. J. , Kasapi, M. , McLeod, H. L. , Roden, D. M. , Williams, M. S. , Green, E. D. , Rodriguez, L. L. , Aronson, S. , Cavallari, L. H. , Denny, J. C. , Dressler, L. G. , Johnson, J. A. , Klein, T. E. , Leeder, J. S. , Piquette-Miller, M. & 12 others Perera, M., Rasmussen-Torvik, L. J., Rehm, H. L., Ritchie, M. D., Skaar, T. C., Wagle, N., Weinshilboum, R., Weitzel, K. W., Wildin, R., Wilson, J., Manolio, T. A. & Relling, M. V. May 1 2018 In : Clinical Pharmacology and Therapeutics. 103, 5, p. 778-786 9 p.

Research output: Contribution to journalArticle

Pharmacogenetics
Research
Pharmaceutical Preparations
Precision Medicine
Drug-Related Side Effects and Adverse Reactions

Rifampin modulation of xeno- and endobiotic conjugating enzyme mRNA expression and associated microRNAs in human hepatocytes

Gufford, B. T., Robarge, J. D., Eadon, M. T., Gao, H., Lin, H., Liu, Y., Desta, Z. & Skaar, T. C. Apr 1 2018 In : Pharmacology Research and Perspectives. 6, 2, e00386

Research output: Contribution to journalArticle

Xenobiotics
Rifampin
MicroRNAs
Hepatocytes
Midazolam
Pragmatic Clinical Trials
Cholinesterase Inhibitors
Caregivers
Alzheimer Disease
Rivastigmine