Todd Skaar

  • 6551 Citations
  • 39 h-Index
1989 …2019
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  • 13 Similar Profiles
Cytochrome P-450 CYP2D6 Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
Tamoxifen Medicine & Life Sciences
Pharmacogenetics Medicine & Life Sciences
Genotype Medicine & Life Sciences
Single Nucleotide Polymorphism Medicine & Life Sciences
Estrogen Receptors Medicine & Life Sciences
exemestane Medicine & Life Sciences

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NIH Grants 2009 2019

RNA Precursors
Protein Splicing
Messenger RNA
Paclitaxel
Computational Biology

Embedding Pharmacogenotyping in an Integrated Health System for the Underserved

Flockhart, D. A., Dexter, P. & Skaar, T.

National Institutes of Health

9/5/146/30/18

Project: Research projectResearch Project--Cooperative Agreements

Precision Medicine
Costs and Cost Analysis
Health
Vulnerable Populations
Pharmacogenetics

Regulation of drug metabolizing enzymes by miRNAs

Skaar, T.

National Institutes of Health

9/30/092/28/18

Project: Research projectResearch Project

Drug and Narcotic Control
MicroRNAs
Enzymes
Pharmaceutical Preparations
Cytochrome P-450 Enzyme System

Publications 1989 2018

  • 6551 Citations
  • 39 h-Index
  • 149 Article
  • 1 Review article
2 Citations

Allelic decomposition and exact genotyping of highly polymorphic and structurally variant genes

Numanagić, I., Malikić, S., Ford, M., Qin, X., Toji, L., Radovich, M., Skaar, T. C., Pratt, V. M., Berger, B., Scherer, S. & Sahinalp, S. C., Dec 1 2018, In : Nature Communications. 9, 1, 828

Research output: Contribution to journalArticle

decomposition
gene
allele
genome
assay

CYP2D6 and Endoxifen in Tamoxifen Therapy: A Tribute to David A. Flockhart

Skaar, T. C. & Desta, Z. Jan 1 2018 (Accepted/In press) In : Clinical Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP2D6
Tamoxifen
Guidelines
Clinical Pharmacology
Pharmacogenetics

Medication exposure patterns in primary care patients prescribed pharmacogenetically actionable opioids

Knisely, M. R., Carpenter, J. S., Broome, M. E., Holmes, A. M., Von Ah, D., Skaar, T. & Draucker, C. B., Aug 7 2018, In : Qualitative Report. 23, 8, p. 1861-1875 15 p., 4

Research output: Contribution to journalArticle

patient care
Opioid Analgesics
Primary Health Care
medication
Tramadol

PASSPORT-seq: A novel high-throughput bioassay to functionally test polymorphisms in micro-RNA target sites

Ipe, J., Collins, K. S., Hao, Y., Gao, H., Bhatia, P., Gaedigk, A., Liu, Y. & Skaar, T. C., Jun 15 2018, In : Frontiers in Genetics. 9, JUN, 219

Research output: Contribution to journalArticle

MicroRNAs
Biological Assay
Cell Line
HEK293 Cells
Hep G2 Cells
2 Citations

Research Directions in the Clinical Implementation of Pharmacogenomics: An Overview of US Programs and Projects

Volpi, S. , Bult, C. J. , Chisholm, R. L. , Deverka, P. A. , Ginsburg, G. S. , Jacob, H. J. , Kasapi, M. , McLeod, H. L. , Roden, D. M. , Williams, M. S. , Green, E. D. , Rodriguez, L. L. , Aronson, S. , Cavallari, L. H. , Denny, J. C. , Dressler, L. G. , Johnson, J. A. , Klein, T. E. , Leeder, J. S. , Piquette-Miller, M. & 12 others Perera, M., Rasmussen-Torvik, L. J., Rehm, H. L., Ritchie, M. D., Skaar, T. C., Wagle, N., Weinshilboum, R., Weitzel, K. W., Wildin, R., Wilson, J., Manolio, T. A. & Relling, M. V., May 1 2018, In : Clinical Pharmacology and Therapeutics. 103, 5, p. 778-786 9 p.

Research output: Contribution to journalArticle

Pharmacogenetics
Research
Pharmaceutical Preparations
Precision Medicine
Drug-Related Side Effects and Adverse Reactions