Tracy Vargo-Gogola

  • 1586 Citations
  • 18 h-Index
19982019
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Publications 1998 2019

  • 1586 Citations
  • 18 h-Index
  • 25 Article
  • 4 Conference contribution
2019

Contrast-enhanced mammographic detection of breast microcalcifications using targeted gold nanoparticles

Finamore, T. A., Gies, E. P., Vargo-Gogola, T. & Roeder, R. K., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Calcinosis
Gold
Nanoparticles
Breast
Tissue

Radiographic detection of her2+ breast cancer cells immunotargeted by gold nanoparticles

McGinnity, T. L., Curtis, T. E., Vargo-Gogola, T. & Roeder, R. K., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Gold
Nanoparticles
Limit of Detection
Cells
Breast Neoplasms
2018
2 Citations (Scopus)

Effects of bisphosphonate ligands and PEGylation on targeted delivery of gold nanoparticles for contrast-enhanced radiographic detection of breast microcalcifications

Cole, L. E., McGinnity, T. L., Irimata, L. E., Vargo-Gogola, T. & Roeder, R. K., Jan 1 2018, (Accepted/In press) In : Acta Biomaterialia.

Research output: Contribution to journalArticle

Calcinosis
Diphosphonates
Gold
Nanoparticles
Polyethylene glycols
2017
3 Citations (Scopus)

Nanoparticle imaging probes for molecular imaging with computed tomography and application to cancer imaging

Roeder, R. K., Curtis, T. E., Nallathamby, P. D., Irimata, L. E., McGinnity, T. L., Cole, L. E., Vargo-Gogola, T. & Cowden Dahl, K., 2017, Medical Imaging 2017: Physics of Medical Imaging. SPIE, Vol. 10132. 101320X

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Molecular imaging
Molecular Imaging
Nanoparticles
Tomography
tomography

Radiographic detection of breast cancer cells using immunotargeted gold nanoparticles

McGinnity, T. L., Irimata, L. E., Nallathamby, P. D., Vargo-Gogola, T. & Roeder, R. K., Jan 1 2017, IPMI's 41st Annual International Conference. International Precious Metals Institute, p. 383-389 7 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Gold
Cells
Nanoparticles
2016
53 Citations (Scopus)

Targeted delivery to bone and mineral deposits using bisphosphonate ligands

Cole, L. E., Vargo-Gogola, T. & Roeder, R. K., Apr 1 2016, In : Advanced Drug Delivery Reviews. 99, p. 12-27 16 p.

Research output: Contribution to journalArticle

Diphosphonates
Minerals
Ligands
Bone and Bones
Pharmaceutical Preparations
2015
17 Citations (Scopus)

Contrast-Enhanced X-ray Detection of Microcalcifications in Radiographically Dense Mammary Tissue Using Targeted Gold Nanoparticles

Cole, L. E., Vargo-Gogola, T. & Roeder, R. K., Sep 22 2015, In : ACS Nano. 9, 9, p. 8923-8932 10 p.

Research output: Contribution to journalArticle

Gold
mammary glands
Tissue
gold
Nanoparticles
102 Citations (Scopus)

Gold nanoparticles as contrast agents in X-ray imaging and computed tomography

Cole, L. E., Ross, R. D., Tilley, J. M., Vargo-Gogola, T. & Roeder, R. K., Jan 1 2015, In : Nanomedicine. 10, 2, p. 321-341 21 p.

Research output: Contribution to journalArticle

X Ray Computed Tomography
gold
Gold
Nanoparticles
Contrast Media
2014
31 Citations (Scopus)

Bisphosphonate-functionalized gold nanoparticles for contrast-enhanced X-ray detection of breast microcalcifications

Cole, L. E., Vargo-Gogola, T. & Roeder, R. K., Feb 2014, In : Biomaterials. 35, 7, p. 2312-2321 10 p.

Research output: Contribution to journalArticle

Calcinosis
Diphosphonates
Durapatite
Hydroxyapatite
Gold
24 Citations (Scopus)

Contrast-enhanced X-ray detection of breast microcalcifications in a murine model using targeted gold nanoparticles

Cole, L. E., Vargo-Gogola, T. & Roeder, R. K., Jul 22 2014, In : ACS Nano. 8, 7, p. 7486-7496 11 p.

Research output: Contribution to journalArticle

Calcinosis
Durapatite
Hydroxyapatite
breast
Gold
2013
24 Citations (Scopus)

Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migration

Bray, K., Gillette, M., Young, J., Loughran, E., Hwang, M., Sears, J. C. & Vargo-Gogola, T., Sep 30 2013, In : Breast Cancer Research. 15, 5, R91.

Research output: Contribution to journalArticle

Human Mammary Glands
Cell Movement
Breast
Morphogenesis
rho GTP-Binding Proteins
7 Citations (Scopus)

P190B RhoGAP Overexpression in the Developing Mammary Epithelium Induces TGFβ-dependent Fibroblast Activation

Gillette, M., Bray, K., Blumenthaler, A. & Vargo-Gogola, T., May 22 2013, In : PLoS One. 8, 5, e65105.

Research output: Contribution to journalArticle

Fibroblasts
breasts
fibroblasts
Breast
epithelium
2012
3 Citations (Scopus)

P190B RhoGAP regulates chromosome segregation in cancer cells

Hwang, M., Peddibhotla, S., McHenry, P., Chang, P., Yochum, Z., Park, K. U., Sears, J. C. & Vargo-Gogola, T., Jun 2012, In : Cancers. 4, 2, p. 475-489 15 p.

Research output: Contribution to journalArticle

Chromosome Segregation
Mitosis
Neoplasms
MCF-7 Cells
Aneuploidy
2011
11 Citations (Scopus)

P190A RhoGAP is required for mammary gland development

Heckman-Stoddard, B. M., Vargo-Gogola, T., Herrick, M. P., Visbal, A. P., Lewis, M. T., Settleman, J. & Rosen, J. M., Dec 1 2011, In : Developmental Biology. 360, 1, p. 1-10 10 p.

Research output: Contribution to journalArticle

Human Mammary Glands
Breast
Transplants
Adipose Tissue
Transplantation
2010
29 Citations (Scopus)

Cleavage of E-cadherin by matrix metalloproteinase-7 promotes cellular proliferation in nontransformed cell lines via activation of RhoA

Fingleton, B., Lynch, C. C., Vargo-Gogola, T. & Matrisian, L. M., 2010, In : Journal of Oncology. 530745.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 7
Cadherins
Matrix Metalloproteinases
Cell Proliferation
Cell Line
24 Citations (Scopus)

P190B RhoGAP has pro-tumorigenic functions during MMTV-Neu mammary tumorigenesis and metastasis

McHenry, P. R., Sears, J. C., Herrick, M. P., Chang, P., Heckman-Stoddard, B. M., Rybarczyk, M., Chodosh, L. A., Gunther, E. J., Hilsenbeck, S. G., Rosen, J. M. & Vargo-Gogola, T., Sep 22 2010, In : Breast Cancer Research. 12, 5, R73.

Research output: Contribution to journalArticle

Carcinogenesis
Breast
rho GTP-Binding Proteins
Neoplasm Metastasis
Reactive Oxygen Species
18 Citations (Scopus)

Pleiotropic functions of Rho GTPase signaling: A Trojan Horse or Achilles' heel for breast cancer treatment?

McHenry, P. R. & Vargo-Gogola, T., 2010, In : Current Drug Targets. 11, 9, p. 1043-1058 16 p.

Research output: Contribution to journalArticle

rho GTP-Binding Proteins
Oncology
Breast Neoplasms
Tumors
Stochastic Processes
1 Citation (Scopus)
Molecular Targeted Therapy
Stem Cell Niche
Tumor Microenvironment
Neoplastic Stem Cells
Stem cells
2009
19 Citations (Scopus)

Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression

Heckman-Stoddard, B. M., Vargo-Gogola, T., McHenry, P. R., Jiang, V., Herrick, M. P., Hilsenbeck, S. G., Settleman, J. & Rosen, J. M., Aug 24 2009, In : Breast Cancer Research. 11, 4, R61.

Research output: Contribution to journalArticle

Haploinsufficiency
Neoplasms
Human Mammary Glands
Breast Neoplasms
rho GTPase-activating protein
2007
27 Citations (Scopus)

Crosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud development

Heckman, B. M., Chakravarty, G., Vargo-Gogola, T., Gonzales-Rimbau, M., Hadsell, D. L., Lee, A. V., Settleman, J. & Rosen, J. M., Sep 1 2007, In : Developmental Biology. 309, 1, p. 137-149 13 p.

Research output: Contribution to journalArticle

Breast
Embryonic Structures
Morphogenesis
Gene Deletion
Mesoderm
51 Citations (Scopus)

Matrix metalloproteinase 7 mediates mammary epithelial cell tumorigenesis through the ErbB4 receptor

Lynch, C. C., Vargo-Gogola, T., Martin, M. D., Fingleton, B., Crawford, H. C. & Matrisian, L. M., Jul 15 2007, In : Cancer Research. 67, 14, p. 6760-6767 8 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 7
Carcinogenesis
Breast
Epithelial Cells
Cell Line
395 Citations (Scopus)

Modelling breast cancer: One size does not fit all

Vargo-Gogola, T. & Rosen, J. M., Sep 2007, In : Nature Reviews Cancer. 7, 9, p. 659-672 14 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Heterografts
Cell Line
2006
31 Citations (Scopus)

p190-B Rho GTPase-activating protein overexpression disrupts ductal morphogenesis and induces hyperplastic lesions in the developing mammary gland

Vargo-Gogola, T., Heckman, B. M., Gunther, E. J., Chodosh, L. A. & Rosen, J. M., Jun 2006, In : Molecular Endocrinology. 20, 6, p. 1391-1405 15 p.

Research output: Contribution to journalArticle

Human Mammary Glands
Morphogenesis
Pregnancy
Tetracycline
Hyperplasia
2005
250 Citations (Scopus)

MMP-7 promotes prostate cancer-induced osteolysis via the solubilization of RANKL

Lynch, C. C., Hikosaka, A., Acuff, H. B., Martin, M. D., Kawai, N., Singh, R. K., Vargo-Gogola, T., Begtrup, J. L., Peterson, T. E., Fingleton, B., Shirai, T., Matrisian, L. M. & Futakuchi, M., May 2005, In : Cancer Cell. 7, 5, p. 485-496 12 p.

Research output: Contribution to journalArticle

Osteolysis
Matrix Metalloproteinases
Prostatic Neoplasms
Osteoclasts
Apolipoproteins D
114 Citations (Scopus)

Pleiotropic effects of FGFR1 on cell proliferation, survival, and migration in a 3D mammary epithelial cell model

Xian, W., Schwertfeger, K. L., Vargo-Gogola, T. & Rosen, J. M., Nov 21 2005, In : Journal of Cell Biology. 171, 4, p. 663-673 11 p.

Research output: Contribution to journalArticle

Cell Movement
Cell Survival
Breast
Epithelial Cells
Cell Proliferation
2002
106 Citations (Scopus)

Identification of novel matrix metalloproteinase-7 (matrilysin) cleavage sites in murine and human Fas ligand

Vargo-Gogola, T., Crawford, H. C., Fingleton, B. & Matrisian, L. M., 2002, In : Archives of Biochemistry and Biophysics. 408, 2, p. 155-161 7 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 7
Fas Ligand Protein
Matrix Metalloproteinase 3
Matrix Metalloproteinase 2
Bioactivity
59 Citations (Scopus)

Matrilysin (matrix metalloproteinase-7) selects for apoptosis-resistant mammary cells in vivo

Vargo-Gogola, T., Fingleton, B., Crawford, H. C. & Matrisian, L. M., Oct 1 2002, In : Cancer Research. 62, 19, p. 5559-5563 5 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 7
Breast
Apoptosis
Fas Ligand Protein
Human Mammary Glands
2001
120 Citations (Scopus)

Matrilysin [MMP-7] expression selects for cells with reduced sensitivity to apoptosis

Fingleton, B., Vargo-Gogola, T., Crawford, H. C. & Matrisian, L. M., 2001, In : Neoplasia. 3, 6, p. 459-468 10 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 7
Matrix Metalloproteinases
Apoptosis
Neoplasms
Cell Line
1998
65 Citations (Scopus)

Direct evidence for rapid degradation of bacillus thuringiensis toxin mRNA as a cause of poor expression in plants

Jay De Rocher, E., Vargo-Gogola, T., Diehn, S. H. & Green, P. J., 1998, In : Plant Physiology. 117, 4, p. 1445-1461 17 p.

Research output: Contribution to journalArticle

Bacillus thuringiensis
toxins
Messenger RNA
degradation
Tobacco