Yansheng Du

  • 6850 Citations
  • 41 h-Index
1991 …2020

Research output per year

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Publications

  • 6850 Citations
  • 41 h-Index
  • 87 Article
  • 4 Comment/debate
  • 4 Letter
  • 4 Review article
2020

Altered clearance of beta-amyloid from the cerebrospinal fluid following subchronic lead exposure in rats: Roles of RAGE and LRP1 in the choroid plexus

Shen, X., Xia, L., Liu, L., Jiang, H., Shannahan, J., Du, Y. & Zheng, W., Sep 2020, In : Journal of Trace Elements in Medicine and Biology. 61, 126520.

Research output: Contribution to journalArticle

Minocycline protects neurons against glial cells-mediated bilirubin neurotoxicity

Zhou, C., Sun, R., Sun, C., Gu, M., Guo, C., Zhang, J., Du, Y., Gu, H. & Liu, Q., Jan 2020, In : Brain Research Bulletin. 154, p. 102-105 4 p.

Research output: Contribution to journalArticle

2019

IVIG Delays Onset in a Mouse Model of Gerstmann-Sträussler-Scheinker Disease

Gu, H., Kirchhein, Y., Zhu, T., Zhao, G., Peng, H., Du, E., Liu, J., Mastrianni, J. A., Farlow, M. R., Dodel, R. & Du, Y., Apr 1 2019, In : Molecular Neurobiology. 56, 4, p. 2353-2361 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

MicroRNA-15a inhibits inflammatory response and apoptosis after spinal cord injury via targeting STAT3

Wu, W. D., Wang, L. H., Wei, N. X., Kong, D. H., Shao, G., Zhang, S. R. & Du, Y. S., 2019, In : European Review for Medical and Pharmacological Sciences. 23, 21, p. 9189-9198 10 p.

Research output: Contribution to journalArticle

2018
3 Scopus citations

Authors' response

Jiang, F., Chen, J., Kula, K., Gu, H., Du, Y. & Eckert, G., Jan 1 2018, In : American Journal of Orthodontics and Dentofacial Orthopedics. 153, 1, 1 p.

Research output: Contribution to journalLetter

Erratum to: Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice (Scientific Reports, (2017), 7, 1, (492), 10.1038/s41598-017-00461-9)

Gu, H., Ma, Z., Wang, J., Zhu, T., Du, N., Shatara, A., Yi, X., Kowala, M. C. & Du, Y., Dec 1 2018, In : Scientific Reports. 8, 1, 16077.

Research output: Contribution to journalComment/debate

The plasma level changes of VEGF and soluble VEGF receptor-1 are associated with high-altitude pulmonary edema

Zhang, S., Liu, J., Jiang, D., Wuren, T., Ma, S., Du, Y., Yi, X. & Wu, S., Jan 1 2018, In : Journal of Medical Investigation. 65, 1-2, p. 64-68 5 p.

Research output: Contribution to journalArticle

1 Scopus citations
2017

Oxaloacetate and adipose stromal cells-conditional medium synergistically protected potassium/serum deprivation-induced neuronal apoptosis

Liu, Q., Zhao, G., Zhou, C., Farlow, M., Du, Y., Xu, G. & Gu, H., Jan 1 2017, In : Brain Research Bulletin. 128, p. 7-12 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Protective effect of edaravone against Aβ25-35-induced mitochondrial oxidative damage in SH-SY5Y cells

Zhang, G. L., Zhang, L., Guo, Y. Y., Ma, Z. L., Wang, H. Y., Li, T., Liu, J., Du, Y., Yao, L., Li, T. T. & Du, J. M., 2017, In : Cellular and Molecular Biology. 63, 5, p. 36-42 7 p., 8.

Research output: Contribution to journalArticle

2 Scopus citations

Root resorptions associated with canine retraction treatment

Jiang, F., Chen, J., Kula, K., Gu, H., Du, Y. & Eckert, G., Sep 2017, In : American Journal of Orthodontics and Dentofacial Orthopedics. 152, 3, p. 348-354 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice

Gu, H., Ma, Z., Wang, J., Zhu, T., Du, N., Shatara, A., Yi, X., Kowala, M. C. & Du, Y., Dec 1 2017, In : Scientific reports. 7, 1, 492.

Research output: Contribution to journalArticle

8 Scopus citations

Sevoflurane preconditioning ameliorates traumatic spinal cord injury through caveolin-3-dependent cyclooxygenase-2 inhibition

Wu, W., Wei, N., Wang, L., Kong, D., Shao, G., Qin, Y., Wang, L. & Du, Y., 2017, In : Oncotarget. 8, 50, p. 87658-87666 9 p.

Research output: Contribution to journalArticle

1 Scopus citations
2016

Erratum: Adipose-derived Stem Cell Conditioned Media Extends Survival time of a mouse model of Amyotrophic Lateral Sclerosis (Scientific Reports (2015) 5 (16953) DOI: 10.1038/srep16953)

Fontanilla, C. V., Gu, H., Liu, Q., Zhu, T. Z., Zhou, C., Johnstone, B. H., March, K. L., Pascuzzi, R. M., Farlow, M. R. & Du, Y., Apr 15 2016, In : Scientific reports. 6, 20747.

Research output: Contribution to journalComment/debate

GDNF secreted from adipose-derived stem cells stimulates VEGF-independent angiogenesis

Zhong, Z., Gu, H., Peng, J., Wang, W., Johnstone, B. H., March, K. L., Farlow, M. R. & Du, Y., Jan 1 2016, In : Oncotarget. 7, 24, p. 36829-36841 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

High glucose-induced Matrilin-2 expression in mouse mesangial cells was mediated by transforming growth factor beta 1 (TGF-β1)

Zhang, S., Zhang, M., Huang, H., Zhou, S., Du, Y., Yi, X. & Luo, J., May 27 2016, In : Biochemical and Biophysical Research Communications. 474, 2, p. 303-308 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Metformin prevents cerebellar granule neurons against glutamate-induced neurotoxicity

Zhou, C., Sun, R., Zhuang, S., Sun, C., Jiang, Y., Cui, Y., Li, S., Xiao, Y., Du, Y., Gu, H. & Liu, Q., Mar 1 2016, In : Brain Research Bulletin. 121, p. 241-245 5 p.

Research output: Contribution to journalArticle

15 Scopus citations
2015

Adipose-derived Stem Cell Conditioned Media Extends Survival time of a mouse model of Amyotrophic Lateral Sclerosis

Fontanilla, C. V., Gu, H., Liu, Q., Zhu, T. Z., Zhou, C., Johnstone, B. H., March, K. L., Pascuzzi, R. M., Farlow, M. R. & Du, Y., Nov 20 2015, In : Scientific reports. 5, 16953.

Research output: Contribution to journalArticle

13 Scopus citations

TIMP1 in conditioned media of human adipose stromal cells protects neurons against oxygen-glucose deprivation injury

Du, S., Mao, G., Zhu, T., Luan, Z., Du, Y. & Gu, H., Jan 1 2015, In : Neuroscience Letters. 584, p. 56-59 4 p.

Research output: Contribution to journalArticle

8 Scopus citations
2014

Adipose stem cells-conditioned medium blocks 6-hydroxydopamine-induced neurotoxicity via the IGF-1/PI3K/AKT pathway

Wang, X., Zhao, Z., Gong, J., Zhou, S., Peng, H., Shatara, A., Zhu, T. Z., Meltzer, R., Du, Y. & Gu, H., Oct 3 2014, In : Neuroscience Letters. 581, p. 98-102 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Design, synthesis, and biological evaluation of (E)-3,4-dihydroxystyryl aralkyl sulfones and sulfoxides as novel multifunctional neuroprotective agents

Ning, X., Guo, Y., Wang, X., Ma, X., Tian, C., Shi, X., Zhu, R., Cheng, C., Du, Y., Ma, Z., Zhang, Z. & Liu, J., May 22 2014, In : Journal of Medicinal Chemistry. 57, 10, p. 4302-4312 11 p.

Research output: Contribution to journalArticle

41 Scopus citations

The role of choroid plexus in IVIG-induced beta-amyloid clearance

Gu, H., Zhong, Z., Jiang, W., Du, E., Dodel, R., Liu, J., Farlow, M. R., Zheng, W. & Du, Y., Jun 13 2014, In : Neuroscience. 270, p. 168-176 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Upregulation of zinc transporter 2 in the blood-CSF barrier following lead exposure

Fu, X., Zeng, A., Zheng, W. & Du, Y., Feb 1 2014, In : Experimental Biology and Medicine. 239, 2, p. 202-212 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
2013

Adipose stromal cells-conditioned medium blocks 6-hydroxydopamine-induced neurotoxicity and reactive oxygen species

Gu, H., Wang, J., Du, N., Tan, J., Johnstone, B. & Du, Y., Jun 7 2013, In : Neuroscience Letters. 544, p. 15-19 5 p.

Research output: Contribution to journalArticle

13 Scopus citations

Immunotherapy in prion disease

Roettger, Y., Du, Y., Bacher, M., Zerr, I., Dodel, R. & Bach, J. P., Feb 1 2013, In : Nature Reviews Neurology. 9, 2, p. 98-105 8 p.

Research output: Contribution to journalReview article

30 Scopus citations

Novel pyridinone derivatives as non-nucleoside reverse transcriptase inhibitors (NNRTIs) with high potency against NNRTI-resistant HIV-1 strains

Li, A., Ouyang, Y., Wang, Z., Cao, Y., Liu, X., Ran, L., Li, C., Li, L., Zhang, L., Qiao, K., Xu, W., Huang, Y., Zhang, Z., Tian, C., Liu, Z., Jiang, S., Shao, Y., Du, Y., Ma, L., Wang, X. & 1 others, Liu, J., May 9 2013, In : Journal of Medicinal Chemistry. 56, 9, p. 3593-3608 16 p.

Research output: Contribution to journalArticle

27 Scopus citations
2012

Caffeic acid phenethyl ester extends survival of a mouse model of amyotrophic lateral sclerosis

Fontanilla, C. V., Wei, X., Zhao, L., Johnstone, B., Pascuzzi, R. M., Farlow, M. R. & Du, Y., Mar 15 2012, In : Neuroscience. 205, p. 185-193 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

Human anti-prion antibodies block prion peptide fibril formation and neurotoxicity

Wei, X., Roettger, Y., Tan, B., He, Y., Dodel, R., Hampel, H., Wei, G., Haney, J., Gu, H., Johnstone, B. H., Liu, J., Farlow, M. R. & Du, Y., Apr 13 2012, In : Journal of Biological Chemistry. 287, 16, p. 12858-12866 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Increased β-amyloid deposition in Tg-SWDI transgenic mouse brain following in vivo lead exposure

Gu, H., Robison, G., Hong, L., Barrea, R., Wei, X., Farlow, M. R., Pushkar, Y. N., Du, Y. & Zheng, W., Sep 3 2012, In : Toxicology Letters. 213, 2, p. 211-219 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Mechanism-based design, synthesis and biological studies of N 5-substituted tetrahydrofolate analogs as inhibitors of cobalamin-dependent methionine synthase and potential anticancer agents

Zhang, Z., Tian, C., Zhou, S., Wang, W., Guo, Y., Xia, J., Liu, Z., Wang, B., Wang, X., Golding, B. T., Griff, R. J., Du, Y. & Liu, J., Dec 1 2012, In : European Journal of Medicinal Chemistry. 58, p. 228-236 9 p.

Research output: Contribution to journalArticle

13 Scopus citations
2011

AMP-activated kinase mediates adipose stem cell-stimulated neuritogenesis of PC12 cells

Tan, B., Luan, Z., Wei, X., He, Y., Wei, G., Johnstone, B. H., Farlow, M. & Du, Y., May 5 2011, In : Neuroscience. 181, p. 40-47 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Association of clusterin gene polymorphisms with late-onset Alzheimer's disease

Gu, H., Wei, X., Chen, S., Kurz, A., Müller, U., Gasser, T., Dodel, R. C., Farlow, M. R. & Du, Y., Dec 1 2011, In : Dementia and Geriatric Cognitive Disorders. 32, 3, p. 198-201 4 p.

Research output: Contribution to journalArticle

21 Scopus citations

Caffeic acid phenethyl ester prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration

Fontanilla, C. V., Ma, Z., Wei, X., Klotsche, J., Zhao, L., Wisniowski, P., Dodel, R. C., Farlow, M. R., Oertel, W. H. & Du, Y., Aug 11 2011, In : Neuroscience. 188, p. 135-141 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Lead exposure increases levels of β-amyloid in the brain and CSF and inhibits LRP1 expression in APP transgenic mice

Gu, H., Wei, X., Monnot, A. D., Fontanilla, C. V., Behl, M., Farlow, M. R., Zheng, W. & Du, Y., Feb 18 2011, In : Neuroscience Letters. 490, 1, p. 16-20 5 p.

Research output: Contribution to journalArticle

38 Scopus citations

Naturally occurring autoantibodies against β-amyloid: Investigating their role in transgenic animal and in vitro models of Alzheimer's disease

Dodel, R., Balakrishnan, K., Keyvani, K., Deuster, O., Neff, F., Andrei-Selmer, L. C., Röskam, S., Stüer, C., Al-Abed, Y., Noelker, C., Balzer-Geldsetzer, M., Oertel, W., Du, Y. & Bacher, M., Apr 13 2011, In : Journal of Neuroscience. 31, 15, p. 5847-5854 8 p.

Research output: Contribution to journalArticle

87 Scopus citations
2010

Intravenous immunoglobulins as a treatment for alzheimers disease: Rationale and current evidence

Dodel, R., Neff, F., Noelker, C., Pul, R., Du, Y., Bacher, M. & Oertel, W., Mar 31 2010, In : Drugs. 70, 5, p. 513-528 16 p.

Research output: Contribution to journalReview article

96 Scopus citations

Lead-induced accumulation of β-amyloid in the choroid plexus: Role of low density lipoprotein receptor protein-1 and protein kinase C

Behl, M., Zhang, Y., Shi, Y., Cheng, J., Du, Y. & Zheng, W., Sep 1 2010, In : NeuroToxicology. 31, 5, p. 524-532 9 p.

Research output: Contribution to journalArticle

35 Scopus citations

Minocycline 1-year therapy in multiple-system-atrophy: Effect on clinical symptoms and [11C] (R)-PK11195 PET (MEMSA-trial)

Dodel, R., Spottke, A., Gerhard, A., Reuss, A., Reinecker, S., Schimke, N., Trenkwalder, C., Sixel-Döring, F., Herting, B., Kamm, C., Gasser, T., Sawires, M., Geser, F., Köllensperger, M., Seppi, K., Kloss, M., Krause, M., Daniels, C., Deuschl, G., Böttger, S. & 13 others, Naumann, M., Lipp, A., Gruber, D., Kupsch, A., Du, Y., Turkheimer, F., Brooks, D. J., Klockgether, T., Poewe, W., Wenning, G., Schade-Brittinger, C., Oertel, W. H. & Eggert, K., Jan 15 2010, In : Movement Disorders. 25, 1, p. 97-107 11 p.

Research output: Contribution to journalArticle

126 Scopus citations
2009

Adipose stromal cells-conditional medium protected glutamate-induced CGNs neuronal death by BDNF

Zhao, L., Wei, X., Ma, Z., Feng, D., Tu, P., Johnstone, B. H., March, K. L. & Du, Y., Mar 20 2009, In : Neuroscience Letters. 452, 3, p. 238-240 3 p.

Research output: Contribution to journalArticle

44 Scopus citations

Adipose stromal cells-secreted neuroprotective media against neuronal apoptosis

Wei, X., Zhao, L., Zhong, J., Gu, H., Feng, D., Johnstone, B. H., March, K. L., Farlow, M. R. & Du, Y., Sep 18 2009, In : Neuroscience Letters. 462, 1, p. 76-79 4 p.

Research output: Contribution to journalArticle

85 Scopus citations

Delayed IGF-1 treatment reduced long-term hypoxia-ischemia-induced brain damage and improved behavior recovery of immature rats

Zhong, J., Zhao, L., Du, Y., Wei, G., Yao, W. G. & Lee, W. H., Jun 1 2009, In : Neurological Research. 31, 5, p. 483-489 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

IFATS collection: The conditioned media of adipose stromal cells protect against hypoxia-ischemia-induced brain damage in neonatal rats

Xing, W., Zhimei, D., Liming, Z., Dongni, F., Gang, W., Yongzheng, H., Jiangning, T., Lee, W. H., Hampel, H., Dodel, R., Johnstone, B. H., March, K. L., Farlow, M. R. & Yansheng, D., Feb 1 2009, In : STEM CELLS. 27, 2, p. 478-488 11 p.

Research output: Contribution to journalArticle

162 Scopus citations

Peripheral and central biodistribution of 111In-labeled anti-beta-amyloid autoantibodies in a transgenic mouse model of Alzheimer's disease

Bacher, M., Depboylu, C., Du, Y., Noelker, C., Oertel, W. H., Behr, T., Henriksen, G., Behe, M. & Dodel, R., Jan 16 2009, In : Neuroscience Letters. 449, 3, p. 240-245 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Pu-erh tea aqueous extracts lower atherosclerotic risk factors in a rat hyperlipidemia model

Hou, Y., Shao, W., Xiao, R., Xu, K., Ma, Z., Johnstone, B. H. & Du, Y., Jun 1 2009, In : Experimental Gerontology. 44, 6-7, p. 434-439 6 p.

Research output: Contribution to journalArticle

98 Scopus citations
2008

Caffeic acid phenethyl ester prevents cerebellar granule neurons (CGNs) against glutamate-induced neurotoxicity

Wei, X., Ma, Z., Fontanilla, C. V., Zhao, L., Xu, Z. C., Taggliabraci, V., Johnstone, B. H., Dodel, R. C., Farlow, M. R. & Du, Y., Sep 9 2008, In : Neuroscience. 155, 4, p. 1098-1105 8 p.

Research output: Contribution to journalArticle

45 Scopus citations

Immunotherapy and naturally occurring autoantibodies in neurodegenerative disorders

Neff, F., Wei, X., Nölker, C., Bacher, M., Du, Y. & Dodel, R., Jun 1 2008, In : Autoimmunity Reviews. 7, 6, p. 501-507 7 p.

Research output: Contribution to journalReview article

49 Scopus citations
2007

C/T conversion alters interleukin-1A promoter function in a human astrocyte cell line

Wei, X., Chen, X., Fontanilla, C., Zhao, L., Liang, Z., Dodel, R., Hampel, H., Farlow, M. & Du, Y., Feb 27 2007, In : Life Sciences. 80, 12, p. 1152-1156 5 p.

Research output: Contribution to journalArticle

8 Scopus citations
2006

Caffeic acid phenethyl ester blocks free radical generation and 6-hydroxydopamine-induced neurotoxicity

Ma, Z., Wei, X., Fontanilla, C., Noelker, C., Dodel, R., Hampel, H. & Du, Y., Aug 22 2006, In : Life Sciences. 79, 13, p. 1307-1311 5 p.

Research output: Contribution to journalArticle

33 Scopus citations

α2-Macroglobulin, lipoprotein receptor-related protein and lipoprotein receptor-associated protein and the genetic risk for developing Alzheimer's disease

Depboylu, C., Lohmüller, F., Du, Y., Riemenschneider, M., Kurz, A., Gasser, T., Müller, U. & Dodel, R. C., Jun 12 2006, In : Neuroscience Letters. 400, 3, p. 187-190 4 p.

Research output: Contribution to journalArticle

16 Scopus citations
2005

Albumin protects cultured cerebellar granule neurons against zinc neurotoxicity

Lin, S., Tagliabracci, V. S., Chen, X. & Du, Y., Sep 8 2005, In : NeuroReport. 16, 13, p. 1461-1465 5 p.

Research output: Contribution to journalArticle

4 Scopus citations