Yong Zang

  • 217 Citations
  • 7 h-Index
20092020

Research output per year

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Publications

  • 217 Citations
  • 7 h-Index
  • 29 Article
  • 2 Review article
  • 1 Letter
2020

A Bayesian adaptive phase I/II clinical trial design with late-onset competing risk outcomes

Zhang, Y., Cao, S., Zhang, C., Jin, I. H. & Zang, Y., 2020, (Accepted/In press) In : Biometrics.

Research output: Contribution to journalArticle

Enrollment of Diverse Populations in the INGENIOUS Pharmacogenetics Clinical Trial

Shah-Williams, E., Levy, K. D., Zang, Y., Holmes, A. M., Stoughton, C., Dexter, P. & Skaar, T. C., Jun 25 2020, In : Frontiers in Genetics. 11, 571.

Research output: Contribution to journalArticle

Open Access

Impact of Lung Parenchymal-Only Failure on Overall Survival in Early-Stage Lung Cancer Patients Treated With Stereotactic Ablative Radiotherapy

Elbanna, M., Shiue, K., Edwards, D., Cerra-Franco, A., Agrawal, N., Hinton, J., Mereniuk, T., Huang, C., Ryan, J. L., Smith, J., Aaron, V. D., Burney, H., Zang, Y., Holmes, J., Langer, M., Zellars, R. & Lautenschlaeger, T., 2020, (Accepted/In press) In : Clinical Lung Cancer.

Research output: Contribution to journalArticle

On the Use of Marker Strategy Design to Detect Predictive Marker Effect in Cancer Immunotherapy and Targeted Therapy

Han, Y., Yuan, Y., Cao, S., Li, M. & Zang, Y., Jul 1 2020, In : Statistics in Biosciences. 12, 2, p. 180-195 16 p.

Research output: Contribution to journalArticle

1 Scopus citations

Radiosurgery dose reduction for brain metastases on immunotherapy (RADREMI): A prospective phase I study protocol

McClelland, S., Lautenschlaeger, T., Zang, Y., Hanna, N. H., Shiue, K., Kamer, A. P., Agrawal, N., Ellsworth, S. G., Rhome, R. M. & Watson, G. A., Jul 1 2020, In : Reports of Practical Oncology and Radiotherapy. 25, 4, p. 500-506 7 p.

Research output: Contribution to journalReview article

TSNP: A two-stage nonparametric phase I/II clinical trial design for immunotherapy

Han, Y., Liu, H., Cao, S., Zhang, C. & Zang, Y., 2020, (Accepted/In press) In : Pharmaceutical Statistics.

Research output: Contribution to journalArticle

2019

A Bayesian adaptive marker-stratified design for molecularly targeted agents with customized hierarchical modeling

Zang, Y., Guo, B., Han, Y., Cao, S. & Zhang, C., Jul 10 2019, In : Statistics in Medicine. 38, 15, p. 2883-2896 14 p.

Research output: Contribution to journalArticle

A Bayesian adaptive phase II clinical trial design accounting for spatial variation

Guo, B. & Zang, Y., Nov 1 2019, In : Statistical Methods in Medical Research. 28, 10-11, p. 3187-3204 18 p.

Research output: Contribution to journalArticle

1 Scopus citations

Drug-gene and drug-drug interactions associated with tramadol and codeine therapy in the INGENIOUS trial

Fulton, C. R., Zang, Y., Desta, Z., Rosenman, M. B., Holmes, A. M., Decker, B. S., Zhang, Y., T Callaghan, J., Pratt, V. M., Levy, K. D., Gufford, B. T., Dexter, P. R., Skaar, T. C. & Eadon, M. T., Apr 1 2019, In : Pharmacogenomics. 20, 6, p. 397-408 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

LTMG: a novel statistical modeling of transcriptional expression states in single-cell RNA-Seq data

Wan, C., Chang, W., Zhang, Y., Shah, F., Lu, X., Zang, Y., Zhang, A., Cao, S., Fishel, M. L., Ma, Q. & Zhang, C., Oct 10 2019, In : Nucleic acids research. 47, 18, p. e111

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Robust tests for gene–environment interaction in case-control and case-only designs

Zang, Y., Fung, W. K., Cao, S., Ng, H. K. T. & Zhang, C., Jan 2019, In : Computational Statistics and Data Analysis. 129, p. 79-92 14 p.

Research output: Contribution to journalArticle

2018

An in vivo screen identifies PYGO2 as a driver for metastatic prostate cancer

Lu, X., Pan, X., Wu, C. J., Zhao, D., Feng, S., Zang, Y., Lee, R., Khadka, S., Amin, S. B., Jin, E. J., Shang, X., Deng, P., Luo, Y., Morgenlander, W. R., Weinrich, J., Lu, X., Jiang, S., Chang, Q., Navone, N. M., Troncoso, P. & 2 others, DePinho, R. A. & Wang, Y. A., Jul 15 2018, In : Cancer Research. 78, 14, p. 3823-3833 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Histology, Tumor Volume, and Radiation Dose Predict Outcomes in NSCLC Patients After Stereotactic Ablative Radiotherapy

Shiue, K., Cerra-Franco, A., Shapiro, R., Estabrook, N., Mannina, E. M., Deig, C. R., Althouse, S., Liu, S., Wan, J., Zang, Y., Agrawal, N., Ioannides, P., Liu, Y., Zhang, C., DesRosiers, C., Bartlett, G., Ewing, M., Langer, M. P., Watson, G., Zellars, R. & 2 others, Kong, F. M. & Lautenschlaeger, T., Oct 2018, In : Journal of Thoracic Oncology. 13, 10, p. 1549-1559 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

IDO immune status after chemoradiation may predict survival in lung cancer patients

Wang, W., Huang, L., Jin, J. Y., Jolly, S., Zang, Y., Wu, H., Yan, L., Pi, W., Li, L., Mellor, A. L. & Kong, F. M., Feb 1 2018, In : Cancer Research. 78, 3, p. 809-816 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Optimal two-stage enrichment design correcting for biomarker misclassification

Zang, Y. & Guo, B., Jan 1 2018, In : Statistical Methods in Medical Research. 27, 1, p. 35-47 13 p.

Research output: Contribution to journalArticle

5 Scopus citations
2017

A robust two-stage design identifying the optimal biological dose for phase I/II clinical trials

Zang, Y. & Lee, J. J., Jan 15 2017, In : Statistics in Medicine. 36, 1, p. 27-42 16 p.

Research output: Contribution to journalArticle

8 Scopus citations

EZH2 modifies sunitinib resistance in renal cell carcinoma by kinome reprogramming

Adelaiye-Ogala, R., Budka, J., Damayanti, N. P., Arrington, J., Ferris, M., Hsu, C. C., Chintala, S., Orillion, A., Miles, K. M., Shen, L., Elbanna, M., Ciamporcero, E., Arisa, S., Pettazzoni, P., Draetta, G. F., Seshadri, M., Hancock, B., Radovich, M., Kota, J., Buck, M. & 9 others, Keilhack, H., McCarthy, B. P., Persohn, S. A., Territo, P. R., Zang, Y., Irudayaraj, J., Tao, W. A., Hollenhorst, P. & Pili, R., Dec 1 2017, In : Cancer Research. 77, 23, p. 6651-6666 16 p.

Research output: Contribution to journalArticle

19 Scopus citations

Optimal sequential enrichment designs for phase II clinical trials

Zang, Y. & Yuan, Y., Jan 15 2017, In : Statistics in Medicine. 36, 1, p. 54-66 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Substantial hepatic necrosis is prognostic in fulminant liver failure

Ndekwe, P., Ghabril, M., Zang, Y., Mann, S. A., Cummings, O. & Lin, J., Jun 21 2017, In : World Journal of Gastroenterology. 23, 23, p. 4303-4310 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
2016

Optimal marker-strategy clinical trial design to detect predictive markers for targeted therapy

Zang, Y., Liu, S. & Yuan, Y., Jul 1 2016, In : Biostatistics. 17, 3, p. 549-560 12 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Two-stage marker-stratified clinical trial design in the presence of biomarker misclassification

Zang, Y., Jack Lee, J. & Yuan, Y., Aug 1 2016, In : Journal of the Royal Statistical Society. Series C: Applied Statistics. 65, 4, p. 585-601 17 p.

Research output: Contribution to journalArticle

5 Scopus citations
2015

A Bayesian phase I/II clinical trial design in the presence of informative dropouts

Guo, B., Zang, Y. & Yuan, Y., Jan 1 2015, In : Statistics and its Interface. 8, 2, p. 217-226 10 p.

Research output: Contribution to journalArticle

Optimal marker-adaptive designs for targeted therapy based on imperfectly measured biomarkers

Zang, Y., Liu, S. & Yuan, Y., Aug 1 2015, In : Journal of the Royal Statistical Society. Series C: Applied Statistics. 64, 4, p. 635-650 16 p.

Research output: Contribution to journalArticle

6 Scopus citations
2014

Adaptive clinical trial designs in oncology

Zang, Y. & Lee, J. J., Jan 1 2014, In : Chinese Clinical Oncology. 3, 4, 49.

Research output: Contribution to journalReview article

21 Scopus citations

Adaptive designs for identifying optimal biological dose for molecularly targeted agents

Zang, Y., Lee, J. J. & Yuan, Y., Jun 2014, In : Clinical Trials. 11, 3, p. 319-327 9 p.

Research output: Contribution to journalArticle

31 Scopus citations
2013

A shrinkage method for testing the hardy-weinberg equilibrium in case-control studies

Zang, Y. & Yuan, Y., Nov 2013, In : Genetic epidemiology. 37, 7, p. 743-750 8 p.

Research output: Contribution to journalArticle

2 Scopus citations
2011

Robust Mantel-Haenszel test under genetic model uncertainty allowing for covariates in case-control association studies

Zang, Y. & Fung, W. K., Nov 1 2011, In : Genetic epidemiology. 35, 7, p. 695-705 11 p.

Research output: Contribution to journalArticle

6 Scopus citations
2010

Asymptotic powers for matched trend tests and robust matched trend tests in case-control genetic association studies

Zang, Y., Fung, W. K. & Zheng, G., Jan 1 2010, In : Computational Statistics and Data Analysis. 54, 1, p. 65-77 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Robust tests for matched case-control genetic association studies

Zang, Y. & Fung, W. K., Oct 12 2010, In : BMC Genetics. 11, 91.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Simple algorithms to calculate asymptotic null distributions of robust tests in case-control genetic association studies in R

Zang, Y., Fung, W. K. & Zheng, G., Jan 1 2010, In : Journal of Statistical Software. 33, 8, p. 1-24 24 p.

Research output: Contribution to journalArticle

Open Access
45 Scopus citations
2009

Tail strength to combine two p values: Their correlation cannot be ignored

Zang, Y., Fung, W. K. & Zheng, G., Feb 13 2009, In : American Journal of Human Genetics. 84, 2, p. 291-295 5 p.

Research output: Contribution to journalLetter

Open Access
2 Scopus citations