Yuichiro Takagi

  • 1330 Citations
  • 17 h-Index
1994 …2020

Research output per year

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Publications

  • 1330 Citations
  • 17 h-Index
  • 28 Article
  • 3 Review article
  • 1 Comment/debate
1994

Phosrestin I undergoes the earliest light-induced phosphorylation by a calcium/calmodulin-dependent protein kinase in drosophila photoreceptors

Matsumoto, H., Kurien, B. T., Takagi, Y., Kahn, E. S., Kinumi, T., Komori, N., Yamada, T., Hayashi, F., Isono, K., Pak, W. L., Jackson, K. W. & Tobin, S. L., May 1994, In : Neuron. 12, 5, p. 997-1010 14 p.

Research output: Contribution to journalArticle

93 Scopus citations
1995
Open Access
12 Scopus citations
1996

Characterization of elongin C functional domains required for interaction with Elongin B and activation of Elongin A

Takagi, Y., Conaway, R. C. & Conaway, J. W., Oct 19 1996, In : Journal of Biological Chemistry. 271, 41, p. 25562-25568 7 p.

Research output: Contribution to journalArticle

20 Scopus citations
1997

Identification of elongin C sequences required for interaction with the von Hippel-Lindau tumor suppressor protein

Takagi, Y., Pause, A., Conaway, R. C. & Conaway, J. W., Nov 1 1997, In : Journal of Biological Chemistry. 272, 43, p. 27444-27449 6 p.

Research output: Contribution to journalArticle

11 Scopus citations
1999

Synthetic peptides define critical contacts between elongin C, elongin B, and the von Hippel-Lindau protein

Ohh, M., Takagi, Y., Aso, T., Stebbins, C. E., Pavletich, N. P., Zbar, B., Conaway, R. C., Conaway, J. W. & Kaelin, W. G., Dec 1999, In : Journal of Clinical Investigation. 104, 11, p. 1583-1591 9 p.

Research output: Contribution to journalArticle

Open Access
79 Scopus citations

The Elongin B ubiquitin homology domain. Identification of Elongin B sequences important for interaction with Elongin C

Brower, C. S., Shilatifard, A., Mather, T., Kamura, T., Takagi, Y., Haque, D., Treharne, A., Foundling, S. I., Conaway, J. W. & Conaway, R. C., May 7 1999, In : Journal of Biological Chemistry. 274, 19, p. 13629-13636 8 p.

Research output: Contribution to journalArticle

16 Scopus citations
2001

A Multiprotein Complex That Interacts with RNA Polymerase II Elongator

Li, Y., Takagi, Y., Jiang, Y., Tokunaga, M., Erdjument-Bromage, H., Tempst, P. & Kornberg, R. D., Aug 10 2001, In : Journal of Biological Chemistry. 276, 32, p. 29628-29631 4 p.

Research output: Contribution to journalArticle

56 Scopus citations
2002

Structure of the yeast RNA polymerase II holoenzyme: Mediator conformation and polymerase interaction

Davis, J. A., Takagi, Y., Kornberg, R. D. & Asturias, F. J., Aug 2002, In : Molecular Cell. 10, 2, p. 409-415 7 p.

Research output: Contribution to journalArticle

167 Scopus citations
2003

Revised Subunit Structure of Yeast Transcription Factor IIH (TFIIH) and Reconciliation with Human TFIIH

Takagi, Y., Komori, H., Chang, W. H., Hudmon, A., Erdjument-Bromage, H., Tempst, P. & Kornberg, R. D., Nov 7 2003, In : Journal of Biological Chemistry. 278, 45, p. 43897-43900 4 p.

Research output: Contribution to journalArticle

32 Scopus citations
2005

Preponderance of free mediator in the yeast Saccharomyces cerevisiae

Takagi, Y., Chadick, J. Z., Davis, J. A. & Asturias, F. J., Sep 2 2005, In : Journal of Biological Chemistry. 280, 35, p. 31200-31207 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Ubiquitin ligase activity of TFIIH and the transcriptional response to DNA damage

Takagi, Y., Masuda, C. A., Chang, W. H., Komori, H., Wang, D., Hunter, T., Joazeiro, C. A. P. & Kornberg, R. D., Apr 15 2005, In : Molecular Cell. 18, 2, p. 237-243 7 p.

Research output: Contribution to journalArticle

61 Scopus citations
2006

Head Module Control of Mediator Interactions

Takagi, Y., Calero, G., Komori, H., Brown, J. A., Ehrensberger, A. H., Hudmon, A., Asturias, F. & Kornberg, R. D., Aug 4 2006, In : Molecular Cell. 23, 3, p. 355-364 10 p.

Research output: Contribution to journalArticle

94 Scopus citations

Mediator as a general transcription factor

Takagi, Y. & Kornberg, R. D., Jan 6 2006, In : Journal of Biological Chemistry. 281, 1, p. 80-89 10 p.

Research output: Contribution to journalArticle

120 Scopus citations
2008

Malleable machines in transcription regulation: The Mediator complex

Tóth-Petróczy, Á., Oldfield, C. J., Simon, I., Takagi, Y., Dunker, A. K., Uversky, V. N. & Fuxreiter, M., Dec 2008, In : PLoS computational biology. 4, 12, e1000243.

Research output: Contribution to journalArticle

78 Scopus citations
2009

Mediator Structural Conservation and Implications for the Regulation Mechanism

Cai, G., Imasaki, T., Takagi, Y. & Asturias, F. J., Apr 15 2009, In : Structure. 17, 4, p. 559-567 9 p.

Research output: Contribution to journalArticle

81 Scopus citations
2010

Mediator Head module structure and functional interactions

Cai, G., Imasaki, T., Yamada, K., Cardelli, F., Takagi, Y. & Asturias, F. J., Mar 1 2010, In : Nature Structural and Molecular Biology. 17, 3, p. 273-279 7 p.

Research output: Contribution to journalArticle

68 Scopus citations
2011

Architecture of the Mediator head module

Imasaki, T., Calero, G., Cai, G., Tsai, K. L., Yamada, K., Cardelli, F., Erdjument-Bromage, H., Tempst, P., Berger, I., Kornberg, G. L., Asturias, F. J., Kornberg, R. D. & Takagi, Y., Jul 14 2011, In : Nature. 475, 7355, p. 240-243 4 p.

Research output: Contribution to journalArticle

84 Scopus citations

Substrate specificity of lymphoid-specific tyrosine phosphatase (Lyp) and identification of Src Kinase-associated Protein of 55 kDa Homolog (SKAP-HOM) as a Lyp substrate

Yu, X., Chen, M., Zhang, S., Yu, Z. H., Sun, J. P., Wang, L., Liu, S., Imasaki, T., Takagi, Y. & Zhang, Z. Y., Sep 2 2011, In : Journal of Biological Chemistry. 286, 35, p. 30526-30534 9 p.

Research output: Contribution to journalArticle

21 Scopus citations
2012

Interaction of the mediator head module with RNA polymerase II

Cai, G., Chaban, Y. L., Imasaki, T., Kovacs, J. A., Calero, G., Penczek, P. A., Takagi, Y. & Asturias, F. J., May 9 2012, In : Structure. 20, 5, p. 899-910 12 p.

Research output: Contribution to journalArticle

26 Scopus citations

MultiBac: Expanding the research toolbox for multiprotein complexes

Bieniossek, C., Imasaki, T., Takagi, Y. & Berger, I., Feb 1 2012, In : Trends in Biochemical Sciences. 37, 2, p. 49-57 9 p.

Research output: Contribution to journalReview article

120 Scopus citations

MultiBac complexomics

Trowitzsch, S., Palmberger, D., Fitzgerald, D., Takagi, Y. & Berger, I., Aug 1 2012, In : Expert Review of Proteomics. 9, 4, p. 363-373 11 p.

Research output: Contribution to journalReview article

12 Scopus citations
2013

Baculovirus expression: Tackling the complexity challenge

Barford, D., Takagi, Y., Schultz, P. & Berger, I., Jun 1 2013, In : Current Opinion in Structural Biology. 23, 3, p. 357-364 8 p.

Research output: Contribution to journalReview article

18 Scopus citations

Expression and purification of functional human glycogen synthase-1 (hGYS1) in insect cells

Khanna, M., Imasaki, T., Chikwana, V. M., Perez-Miller, S., Hunter, G. O., Mosley, A., Takagi, Y. & Hurley, T. D., Jun 20 2013, In : Protein Expression and Purification. 90, 2, p. 78-83 6 p.

Research output: Contribution to journalArticle

7 Scopus citations
2015

Structures and functions of the multiple KOW domains of transcription elongation factor Spt5

Meyer, P. A., Li, S., Zhang, M., Yamada, K., Takagi, Y., Hartzog, G. A. & Fu, J., Jan 1 2015, In : Molecular and cellular biology. 35, 19, p. 3354-3369 16 p.

Research output: Contribution to journalArticle

11 Scopus citations
2017

Yeast Hrq1 shares structural and functional homology with the disease-linked human RecQ4 helicase

Rogers, C. M., Wang, J. C. Y., Noguchi, H., Imasaki, T., Takagi, Y. & Bochman, M. L., May 19 2017, In : Nucleic acids research. 45, 9, p. 5217-5230 14 p.

Research output: Contribution to journalArticle

13 Scopus citations
2018

A protein–protein interaction underlies the molecular basis for substrate recognition by an adenosine-to-inosine RNA-editing enzyme

Rajendren, S., Manning, A. C., Al-Awadi, H., Yamada, K., Takagi, Y. & Hundley, H. A., 2018, In : Nucleic acids research. 46, 18, p. 9647-9659 13 p.

Research output: Contribution to journalArticle

7 Scopus citations

Titer estimation for quality control (TEQC) method: A practical approach for optimal production of protein complexes using the baculovirus expression vector system

Imasaki, T., Wenzel, S., Yamada, K., Bryant, M. L. & Takagi, Y., Apr 2018, In : PloS one. 13, 4, e0195356.

Research output: Contribution to journalArticle

5 Scopus citations
2019

A practical method for efficient and optimal production of Seleno-methionine-labeled recombinant protein complexes in the insect cells

Wenzel, S., Imasaki, T. & Takagi, Y., Apr 2019, In : Protein Science. 28, 4, p. 808-822 15 p.

Research output: Contribution to journalArticle

Author Correction: High-resolution crystal structure of human asparagine synthetase enables analysis of inhibitor binding and selectivity (Communications Biology, (2019), 2, 1, (345), 10.1038/s42003-019-0587-z)

Zhu, W., Radadiya, A., Bisson, C., Wenzel, S., Nordin, B. E., Martínez-Márquez, F., Imasaki, T., Sedelnikova, S. E., Coricello, A., Baumann, P., Berry, A. H., Nomanbhoy, T. K., Kozarich, J. W., Jin, Y., Rice, D. W., Takagi, Y. & Richards, N. G. J., Dec 1 2019, In : Communications Biology. 2, 1, 438.

Research output: Contribution to journalComment/debate

Open Access
1 Scopus citations

High-resolution crystal structure of human asparagine synthetase enables analysis of inhibitor binding and selectivity

Zhu, W., Radadiya, A., Bisson, C., Wenzel, S., Nordin, B. E., Martínez-Márquez, F., Imasaki, T., Sedelnikova, S. E., Coricello, A., Baumann, P., Berry, A. H., Nomanbhoy, T. K., Kozarich, J. W., Jin, Y., Rice, D. W., Takagi, Y. & Richards, N. G. J., Dec 1 2019, In : Communications Biology. 2, 1, 345.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Parkinson’s disease-associated mutations in the GTPase domain of LRRK2 impair its nucleotide-dependent conformational dynamics

Wu, C. X., Liao, J., Park, Y., Reed, X., Engel, V. A., Hoang, N. C., Takagi, Y., Johnson, S. M., Wang, M., Federici, M., Jeremy Nichols, R., Sanishvili, R., Cookson, M. R. & Hoang, Q. Q., Apr 12 2019, In : Journal of Biological Chemistry. 294, 15, p. 5907-5913 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2020

The yeast Hrq1 helicase stimulates Pso2 translesion nuclease activity and thereby promotes DNA interstrand crosslink repair

Rogers, C. M., Lee, C. Y., Parkins, S., Buehler, N. J., Wenzel, S., Martínez-Márquez, F., Takagi, Y., Myong, S. & Bochman, M. L., Jul 3 2020, In : The Journal of biological chemistry. 295, 27, p. 8945-8957 13 p.

Research output: Contribution to journalArticle