Zeruesenay Desta

  • 9291 Citations
  • 43 h-Index
1976 …2019
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  • 8 Similar Profiles
efavirenz Medicine & Life Sciences
Cytochrome P-450 CYP2D6 Medicine & Life Sciences
Tamoxifen Medicine & Life Sciences
Pharmacogenetics Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
Cytochrome P-450 Enzyme System Medicine & Life Sciences
exemestane Medicine & Life Sciences
letrozole Medicine & Life Sciences

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NIH Grants 1976 2018

Drug Interactions
efavirenz
Alleles
Pharmaceutical Preparations
Cytochrome P-450 CYP2B6

Aging Effects on Drug Bioavailability

Desta, Z. & Hall, S.

National Institutes of Health

8/15/027/31/09

Project: Research project

Cytochrome P-450 CYP3A
Drug Interactions
Rifampin
Pharmaceutical Preparations
Pharmacokinetics

CLINICAL PHARMACOLOGY TRAINING GRANT

Flockhart, D. A., Brater, D. C. & Desta, Z.

National Institutes of Health

7/1/926/30/18

Project: Research project

Clinical Pharmacology
Pharmacogenetics
Research
Pharmaceutical Preparations
Organized Financing

GENERAL CLINICAL RESEARCH CENTER

Wilkes, D., Crabb, D., Rex, D., Einhorn, L., Zipes, D., Benson, M., Moe, S., Abonour, R., Farlow, M., Miller, K., Loehrer, P., Cripe, L., Peacock, M., DiMeglio, L., Econs, M., Spinola, S., de Cordon, K., Denne, S., Kwo, P., Agarwal, R., Considine, R., Poindexter, B., Stevens, J., Kraus, M., Chalasani, N., Robertson, M., Logan, T., Croop, J., Groh, W., Robertson, M., Hannon, T., Wojcieszek, J., Considine, R., Mather, K., Chalasani, N., Flockhart, D. A., Foroud, T., Desta, Z., Benson, M., Kareken, D., Poindexter, B., Friedman, A., Gupta, S., Schneider, B., Carpenter, J., Steiner, S., Storniolo, A. M., Cripe, L., Murphy, M., Molleston, J., Hui, S., Von Ah, D., Logan, T., Sawada, S., Fineberg, S. E., Edmondson, J. W., Lumeng, L., O'Connor, K., Clark, C. M., Maxwell, D., Scott, P., Prystowsky, E., Hoffman, R., Brater, C. D., Brandt, I., Bradley, J., Vinicor, F., Williams, S., Weir, C., Heger, J., Thomasson, H., Manolagas, S., Duckworth, W., MacLaren, N., Mohler, E., Baker, J., Vargo, D., Lehman, G., Einhorm, L., Luft, F., Scheller, C., Rudy, D., Merritt, D. H., Kleit, S., Williams, D., Wheeler, M., Twigg, H., Weinberger, M., Wheat, L. J., Holden, R., Rawl, S., Smith, F. O., Shankar, R., Kirkman, S. U. E., Richardson, J., Pratt, J. H., Rodriguez, H., Hall, S., McDougle, C., Brater, D. C., Dropco, E., Krause, M., Baker, S., Wilensky, R., Hamburger, R., Jakacki, R., Oconnor, S., Rink, R., Biller, J., Prince, M., Klaunig, J., Reed, T. E., Harris, A., Myers, S., Jackson, R., Jindal, R., Haehner, B., Johnston, C. C., Black, J., McCaskill-Steve, W., Clark, C., Roos, K., Batiuk, T., Brady, M., Oconner, S., Keck, J., Brashear, A., Timmerman, R., Goldmna, M., Mohler, E. R., Guare, J., Frank, M., Siemers, E., Dropcho, E. J., Davidson, D., Pompili, V., Patrick Loehrer, M. D., Gumbiner, B., Michael Frank, M. D., Wheat, L. J., O'Connor, S., Dusick, A., Ernst, J., Sowinski, K., Batiuk, T., Rushing, D., Stout, J., Bangs, M., Sokol, G., Lemons, J., Gorski, J. C., Johnson, R., Sweeney, C., Dennis Chua, A., Dube, M., Galinsky, R. E., Steinberg, H., Pescovitz, M. D., Twigg, H., Fife, K. H., O'Connor, S. J., Tisdale, J. E., Vik, T., Govani, M., Gardner, T. W., Blekher, T., Kays, M., Johnston, C., Howenstine, M., Dusick, A., Yaqub, M., Kreher, N., Morris, E., Posey, D., Nebesio, T., Ragg, S., Kowolik, M., Ellett, M., Shankar, S., Walvoord, E., Shore, C., Deeg, M., Matei, D., Tisdale, J. E., Bruno, A., Knox, K., Stout, J., Blekher, T., Saifullah, A., Jin, Y. A. N., Griest, A., Nurnberger, J., Hathaway, D., Voelker, J., Abel, L., Faust, H., Brater, C., Garcia, J. O. E., Garvey, T., Johnston, C. C., Fergusson, J., O'Connor, S., Greist, A., Shapiro, A. M. Y., Eigen, H., Roth, B. J., Pescovitz, O., Lemons, J., Pescovitz, M., Rickard, K., Christian, J., Sokol, G., Bradley, J. D., Steinberg, H., Freidenberg, G., Wheat, J., Fife, K., Gordon, M., Pratt, H., Mannix, E., Sledge, G., Sandler, A., Baron, A., Leitch, C. & Goldman, M.

National Institutes of Health

12/1/7611/30/09

Project: Research project

salmon calcitonin
Haemophilus ducreyi
Amyloidosis
Osteoporotic Fractures
Osteoporosis

Publications 1986 2019

  • 9291 Citations
  • 43 h-Index
  • 162 Article
  • 2 Chapter

Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2

Dudenkov, T. M., Liu, D., Cairns, J., Devarajan, S., Zhuang, Y., Ingle, J. N., Buzdar, A. U., Robson, M. E., Kubo, M., Batzler, A., Barman, P., Jenkins, G. D., Carlson, E. E., Goetz, M. P., Northfelt, D. W., Moreno-Aspitia, A., Desta, Z., Reid, J. M., Kalari, K. R., Wang, L. & 1 others, Weinshilboum, R. M., Jan 1 2019, In : Clinical Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Open Access
Aromatase Inhibitors
Genome-Wide Association Study
Single Nucleotide Polymorphism
Pharmaceutical Preparations
Breast Neoplasms
1 Citation (Scopus)

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2B6 and Efavirenz-Containing Antiretroviral Therapy

Desta, Z., Gammal, R. S., Gong, L., Whirl-Carrillo, M., Gaur, A. H., Sukasem, C., Hockings, J., Myers, A., Swart, M., Tyndale, R. F., Masimirembwa, C., Iwuchukwu, O. F., Chirwa, S., Lennox, J., Gaedigk, A., Klein, T. E. & Haas, D. W., Jan 1 2019, In : Clinical Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Open Access
efavirenz
Pharmacogenetics
Guidelines
Reverse Transcriptase Inhibitors
HIV Infections

CYP2B6 Genotype-Dependent Inhibition of CYP1A2 and Induction of CYP2A6 by the Antiretroviral Drug Efavirenz in Healthy Volunteers

Metzger, I. F., Dave, N., Kreutz, Y., Lu, J. B. L., Galinsky, R. E. & Desta, Z., Jan 1 2019, (Accepted/In press) In : Clinical and translational science.

Research output: Contribution to journalArticle

Open Access
efavirenz
Cytochrome P-450 CYP1A2
Healthy Volunteers
Genotype
Pharmaceutical Preparations

Drug-gene and drug-drug interactions associated with tramadol and codeine therapy in the INGENIOUS trial

Fulton, C. R., Zang, Y., Desta, Z., Rosenman, M., Holmes, A., Decker, B., Zhang, Y., T Callaghan, J., Pratt, V. M., Levy, K., Gufford, B. T., Dexter, P., Skaar, T. & Eadon, M., Apr 1 2019, In : Pharmacogenomics. 20, 6, p. 397-408 12 p.

Research output: Contribution to journalArticle

Tramadol
Codeine
Drug Interactions
Cytochrome P-450 CYP2D6
Pharmaceutical Preparations

Effects of SLCO1B1 polymorphisms on plasma estrogen concentrations in women with breast cancer receiving aromatase inhibitors exemestane and letrozole

Dempsey, J. M., Kidwell, K. M., Gersch, C. L., Pesch, A. M., Desta, Z., Storniolo, A. M., Stearns, V., Skaar, T., Hayes, D. F., Henry, N. L., Rae, J. M. & Hertz, D. L., Jan 1 2019, In : Pharmacogenomics. 20, 8, p. 571-580 10 p.

Research output: Contribution to journalArticle

exemestane
letrozole
Aromatase Inhibitors
Estrogens
Breast Neoplasms