Zhong-Yin Zhang

  • 15221 Citations
  • 72 h-Index
1990 …2019
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  • 20 Similar Profiles
Protein Tyrosine Phosphatases Medicine & Life Sciences
Phosphoric Monoester Hydrolases Medicine & Life Sciences
Non-Receptor Type 1 Protein Tyrosine Phosphatase Medicine & Life Sciences
Catalytic Domain Medicine & Life Sciences
Yersinia Medicine & Life Sciences
Tyrosine Medicine & Life Sciences
Substrates Chemical Compounds
Phosphates Medicine & Life Sciences

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NIH Grants 1996 2019

Protein Tyrosine Phosphatases
Mycobacterium
Tuberculosis
Multidrug-Resistant Tuberculosis
Mycobacterium tuberculosis
Protein Tyrosine Phosphatases
Leukemia
Neoplasms
Salicylic Acid
Noonan Syndrome
Liver Neoplasms
Phosphoric Monoester Hydrolases
Neoplasms
Protein Tyrosine Phosphatases
Therapeutics
Non-Receptor Type 1 Protein Tyrosine Phosphatase
Proteomics
Insulin
Obesity
Proteome

Publications 1990 2019

  • 15221 Citations
  • 72 h-Index
  • 249 Article
  • 6 Chapter
  • 3 Review article
  • 2 Letter

First-generation structure-activity relationship studies of 2,3,4,9-tetrahydro-1H-carbazol-1-amines as CpxA phosphatase inhibitors

Li, Y., Gardner, J. J., Fortney, K. R., Leus, I. V., Bonifay, V., Zgurskaya, H. I., Pletnev, A. A., Zhang, S., Zhang, Z-Y., Gribble, G. W., Spinola, S. & Duerfeldt, A. S., Jan 1 2019, In : Bioorganic and Medicinal Chemistry Letters.

Research output: Contribution to journalArticle

Structure-Activity Relationship
Phosphoric Monoester Hydrolases
Amines
Indoles
Scaffolds
1 Citation (Scopus)

Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation

Kano, Y., Gebregiworgis, T., Marshall, C. B., Radulovich, N., Poon, B. P. K., St-Germain, J., Cook, J. D., Valencia-Sama, I., Grant, B. M. M., Herrera, S. G., Miao, J., Raught, B., Irwin, M. S., Lee, J. E., Yeh, J. J., Zhang, Z-Y., Tsao, M. S., Ikura, M. & Ohh, M., Dec 1 2019, In : Nature Communications. 10, 1, 224.

Research output: Contribution to journalArticle

phosphorylation
Phosphorylation
GTP Phosphohydrolases
Conformations
switches
4 Citations (Scopus)

Development and characterization of an endotoxemia model in zebra fish

Hsu, A. Y., Gurol, T., Sobreira, T. J. P., Zhang, S., Moore, N., Cai, C., Zhang, Z-Y. & Deng, Q., Mar 29 2018, In : Frontiers in Immunology. 9, MAR, 607.

Research output: Contribution to journalArticle

Endotoxemia
Zebrafish
Inflammation
Myeloid Differentiation Factor 88
Protein Tyrosine Phosphatases
2 Citations (Scopus)

Insulin regulates POMC neuronal plasticity to control glucose metabolism

Dodd, G. T., Michael, N. J., Lee-Young, R. S., Mangiafico, S. P., Pryor, J. T., Munder, A. C., Simonds, S. E., Brüning, J. C., Zhang, Z-Y., Cowley, M. A., Andrikopoulos, S., Horvath, T. L., Spanswick, D. & Tiganis, T., Sep 19 2018, In : eLife. 7

Research output: Contribution to journalArticle

Pro-Opiomelanocortin
Neuronal Plasticity
Metabolism
Plasticity
Neurons
2 Citations (Scopus)

Quinic Acid-Conjugated Nanoparticles Enhance Drug Delivery to Solid Tumors via Interactions with Endothelial Selectins

Xu, J., Lee, S. S. Y., Seo, H., Pang, L., Jun, Y., Zhang, R. Y., Zhang, Z-Y., Kim, P., Lee, W., Kron, S. J. & Yeo, Y., Jan 1 2018, (Accepted/In press) In : Small. 1803601.

Research output: Contribution to journalArticle

Quinic Acid
Selectins
Drug delivery
Nanoparticles
Tumors