Zhong-Yin Zhang

  • 15604 Citations
  • 72 h-Index
1990 …2020
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  • 13 Similar Profiles
Protein Tyrosine Phosphatases Medicine & Life Sciences
Phosphoric Monoester Hydrolases Medicine & Life Sciences
Non-Receptor Type 1 Protein Tyrosine Phosphatase Medicine & Life Sciences
Catalytic Domain Medicine & Life Sciences
Yersinia Medicine & Life Sciences
Tyrosine Medicine & Life Sciences
Substrates Chemical Compounds
Phosphates Medicine & Life Sciences

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NIH Grants 1996 2019

Protein Tyrosine Phosphatases
Multidrug-Resistant Tuberculosis
Mycobacterium tuberculosis
Protein Tyrosine Phosphatases
Salicylic Acid
Noonan Syndrome
Liver Neoplasms
Phosphoric Monoester Hydrolases
Protein Tyrosine Phosphatases
Non-Receptor Type 1 Protein Tyrosine Phosphatase

Publications 1990 2020

  • 15604 Citations
  • 72 h-Index
  • 251 Article
  • 6 Chapter
  • 3 Review article
  • 2 Letter

PTPN2 phosphatase deletion in T cells promotes anti-tumour immunity and CAR T-cell efficacy in solid tumours

Wiede, F., Lu, K. H., Du, X., Liang, S., Hochheiser, K., Dodd, G. T., Goh, P. K., Kearney, C., Meyran, D., Beavis, P. A., Henderson, M. A., Park, S. L., Waithman, J., Zhang, S., Zhang, Z. Y., Oliaro, J., Gebhardt, T., Darcy, P. K. & Tiganis, T., Jan 15 2020, In : EMBO Journal. 39, 2, e103637.

Research output: Contribution to journalArticle

Open Access
T-Cell Antigen Receptor
Phosphoric Monoester Hydrolases

First-generation structure-activity relationship studies of 2,3,4,9-tetrahydro-1H-carbazol-1-amines as CpxA phosphatase inhibitors

Li, Y., Gardner, J. J., Fortney, K. R., Leus, I. V., Bonifay, V., Zgurskaya, H. I., Pletnev, A. A., Zhang, S., Zhang, Z-Y., Gribble, G. W., Spinola, S. & Duerfeldt, A. S., Jan 1 2019, In : Bioorganic and Medicinal Chemistry Letters.

Research output: Contribution to journalArticle

Structure-Activity Relationship
Phosphoric Monoester Hydrolases

Small Molecules Target the Interaction between Tissue Transglutaminase and Fibronectin

Sima, L. E., Yakubov, B., Zhang, S., Condello, S., Grigorescu, A. A., Nwani, N. G., Chen, L., Schiltz, G. E., Arvanitis, C., Zhang, Z. Y. & Matei, D., Jun 1 2019, In : Molecular cancer therapeutics. 18, 6, p. 1057-1068 12 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Cell-Matrix Junctions
Focal Adhesion Protein-Tyrosine Kinases
4 Citations (Scopus)

Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation

Kano, Y., Gebregiworgis, T., Marshall, C. B., Radulovich, N., Poon, B. P. K., St-Germain, J., Cook, J. D., Valencia-Sama, I., Grant, B. M. M., Herrera, S. G., Miao, J., Raught, B., Irwin, M. S., Lee, J. E., Yeh, J. J., Zhang, Z-Y., Tsao, M. S., Ikura, M. & Ohh, M., Dec 1 2019, In : Nature Communications. 10, 1, 224.

Research output: Contribution to journalArticle

GTP Phosphohydrolases
5 Citations (Scopus)

Development and characterization of an endotoxemia model in zebra fish

Hsu, A. Y., Gurol, T., Sobreira, T. J. P., Zhang, S., Moore, N., Cai, C., Zhang, Z-Y. & Deng, Q., Mar 29 2018, In : Frontiers in Immunology. 9, MAR, 607.

Research output: Contribution to journalArticle

Myeloid Differentiation Factor 88
Protein Tyrosine Phosphatases