Aberrant Monocytic Differentiation Induced by Gain-of-Function Shp2 Mutants

Project: Research project

Description

DESCRIPTION (provided by applicant): Noonan syndrome (NS) is a common (1 in 1500 to 2500 live births) autosomal-dominant disorder caused by mutations in PTPN11 (50%), SOS1 (20%), or KRAS (
StatusFinished
Effective start/end date7/30/096/30/11

Funding

  • National Institutes of Health: $192,870.00
  • National Institutes of Health: $231,380.00

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mutation
mutants

ASJC

  • Medicine(all)