Surrogate markers for Severe Pulmonary Embolism

Project: Research project

Description

DESCRIPTION (provided by applicant): Echocardiography can help risk-stratify the severity of pulmonary embolism (PE) diagnosed in normotensive patients. However, because echocardiography is not uniformly available in U.S. hospitals, more accessible surrogate criteria are needed: to facilitate the immediate recognition of disabling PE in hemodynamically stable patients. Prior work by the Pi has led to the hypothesis that cardiopulmonary stress from severe PE can be recognized by abnormalities in vital signs, the 12- lead ECG and the serum troponin measurement. For this project, a screening instrument to rule out severe PE has been defined asthe combination of a shock index (pulse/systolic blood pressure) 91 percent, a Daniel ECG score
StatusFinished
Effective start/end date7/8/036/30/08

Funding

  • National Institutes of Health: $351,789.00
  • National Institutes of Health: $380,429.00
  • National Institutes of Health: $351,789.00

Fingerprint

Pulmonary Embolism
Biomarkers
Echocardiography
Electrocardiography
Blood Pressure
Troponin
Vital Signs
Pulse
Shock
Serum

ASJC

  • Medicine(all)