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Targeting Ovarian Cancer Stem Cells Through Selective Inhibition of ALDH1A1

Matei, D. & Hurley, T.

National Institutes of Health

7/1/156/30/17

Project: Research projectExploratory/Developmental Grants

Aldehyde Dehydrogenase
Neoplastic Stem Cells
Ovarian Neoplasms
Protein Isoforms
Neoplasms

Regulation of Humoral Immunity by Tox

Kaplan, M.

National Institutes of Health

7/1/156/30/17

Project: Research projectSmall Research Grants

Humoral Immunity
Helper-Inducer T-Lymphocytes
T-Lymphocytes
B-Lymphocytes
Germinal Center

Targeting macrophage Bcl6 to enhance innate resistance to influenza

Sun, J.

National Institutes of Health

7/1/156/30/17

Project: Research projectExploratory/Developmental Grants

Orthomyxoviridae
Human Influenza
Macrophages
Virus Diseases
Pandemics

Development of novel lung cancer therapeutics targeting the DNA damage response

Turchi, J. & Pawelczak, K.

National Institutes of Health

6/1/155/31/16

Project: Research projectSmall Business Technology Transfer (STTR) Grants - Phase I

Xeroderma Pigmentosum
DNA Damage
Lung Neoplasms
DNA Repair
Therapeutics

Optimization of a novel series of thiazolopyridines for the treatment of SMA

Androphy, E., Lorson, C. L. & Hodgetts, K.

National Institutes of Health

4/1/153/31/17

Project: Research projectExploratory/Developmental Grants

Spinal Muscular Atrophy
Therapeutics
Proteins
Pharmacokinetics
Genes

DNA damage and repair in inflammation-induced peripheral sensitization

Vasko, M. & Kelley, M.

National Institutes of Health

2/1/151/31/17

Project: Research projectExploratory/Developmental Grants

Sensory Receptor Cells
DNA Repair
DNA Damage
Inflammation
Dinoprostone

Cyclic di-GMP-dependent regulation of metabolism and virulence in Borrelia burgdorferi

Yang, X. & Gomelsky, M.

National Institutes of Health

1/15/1512/31/16

Project: Research projectExploratory/Developmental Grants

Borrelia burgdorferi
Ticks
Cyclic GMP
Virulence
Mammals
Spinal Cord Injuries
Regeneration
Growth
Axons
Spinal Cord

Endogenous Mitochondria Resistance to Acute Kidney Injury

Bacallao, R.

National Institutes of Health

10/1/149/30/18

Project: Research projectNon-HHS Research Projects

Acute Kidney Injury
Mitochondria
Dialysis
Mortality
Kidney

Genomic Analysis of Parkinson's Disease

Foroud, T. & Landers, J. E.

National Institutes of Health

9/30/147/31/16

Project: Research projectHigh Priority, Short Term Project Award

Parkinson Disease
Exome
Genes
Mutation
Neurodegenerative Diseases

Using a Closed-Loop System Plus Behavioral Supports in Preschoolers with Diabetes

Hannon, T., Slover, R., Maahs, D. M., Buckingham, B. A. & Hood, K.

National Institutes of Health

9/25/149/24/17

Project: Research projectType 1 Diabetes Targeted Research Award

Glucose
Technology
Hypoglycemia
Insulin
Fear

Development of a Multiscale Mechanistic Simulation of Acetaminophen Induced Liver

Dunn, K., Glazier, J. A. & Klaunig, J.

National Institutes of Health

9/25/146/30/18

Project: Research projectResearch Project--Cooperative Agreements

Acetaminophen
Computer Simulation
Liver
Toxicology
Liver Failure

Biomarkers Of Beta Cell Stress In Type 1 Diabetes (BetaMarker)

Mirmira, R., Evans-Molina, C. E., Eizirik, D. L., Nadler, J. L. & Metz, T.

National Institutes of Health

9/23/148/31/17

Project: Research projectHigh Impact Research and Research Infrastructure Cooperative Agreement Programs—Multi-Yr Funding

Type 1 Diabetes Mellitus
Biomarkers
Nucleic Acids
Proteins
Proteomics

Evidence-based Drug-Interaction Discovery: In-Vivo, In-Vitro and Clinical

Li, L., Rocha, L. M. & Shatkay, H.

National Institutes of Health

9/20/147/31/18

Project: Research projectResearch Project

Drug Discovery
Drug Interactions
Pharmaceutical Preparations
In Vitro Techniques
Data Mining

HIV, Depression, and Cardiovascular Risk

Gupta, S., Stewart, J. & Freiberg, M.

National Institutes of Health

9/19/148/31/18

Project: Research projectResearch Project

HIV
Depression
Therapeutics
Inflammation
Depressive Disorder

SkyScan 1176 Micro CT System

Williams, J.

National Institutes of Health

9/15/149/14/15

Project: Research projectBiomedical Research Support Shared Instrumentation Grants

Imaging techniques
Scanning
Animals
Tissue

Homeostatic plasticity in the control of neuropathic pain

Jin, X.

National Institutes of Health

9/15/148/31/18

Project: Research projectResearch Project

Neuralgia
Pharmacology
Spinal Cord Ischemia
Central Nervous System Sensitization
Nervous System Trauma

Physiologic Regulation of Hematopoiesis by Notch

Carlesso, N.

National Institutes of Health

9/15/148/31/18

Project: Research projectResearch Project

Hematopoiesis
Bone Marrow
NF-kappa B
Inflammation
Neoplasms

Pulmonary Hypertension Breakthrough Initiative

Geraci, M., Rabinovitch, M., Erzurum, S. C., Grizzle, W. E. & McLaughlin, V.

National Institutes of Health

9/15/146/30/18

Project: Research projectResource-Related Research Projects

Pulmonary Hypertension
National Heart, Lung, and Blood Institute (U.S.)
Cataloging
Pathology
Lung

Targeting PAK1 to improve functional beta-cell mass and insulin sensitivity

Thurmond, D.

National Institutes of Health

9/12/147/31/18

Project: Research projectResearch Project

Insulin Resistance
Skeletal Muscle
Insulin
Knockout Mice
Muscle Cells

Endothelial mechanisms of impaired lung gas exchange by HIV

Petrache, I., Crothers, K. A. & Schnapp, L.

National Institutes of Health

9/11/1410/31/15

Project: Research projectHigh Priority, Short Term Project Award

Gases
HIV
Lung
Emphysema
Chronic Obstructive Pulmonary Disease

Embedding Pharmacogenotyping in an Integrated Health System for the Underserved

Flockhart, D. A., Dexter, P. & Skaar, T.

National Institutes of Health

9/5/146/30/18

Project: Research projectResearch Project--Cooperative Agreements

Precision Medicine
Costs and Cost Analysis
Health
Vulnerable Populations
Pharmacogenetics

Injury Mechanisms and Systemic Immune Responses after Cerebral Global Ischemia

Xu, Y. & Huanyu, D.

National Institutes of Health

9/1/147/31/18

Project: Research projectResearch Project

Heart Arrest
Brain Ischemia
Wounds and Injuries
Resuscitation
Cytokines

Incentivizing Better Quality in Long-Term Care

Arling, G.

National Institutes of Health

9/1/146/30/15

Project: Research projectConference

health service
nursing home
dialogue
stakeholder
Values

A Translational Bioinformatics Approach in the Drug Interaction Research

Li, L.

National Institutes of Health

9/1/145/31/18

Project: Research projectResearch Project

Computational Biology
Drug Interactions
Research
Pharmaceutical Preparations
Electronic Health Records
Chlamydia
Chlamydia Infections
Pathology
Epithelial Cells
Chemokines
Sudden Cardiac Death
Chronic Kidney Failure
DNA
Single Nucleotide Polymorphism
Calcium-Sensing Receptors

Toward drug treatment of spinal muscular atrophy: Mechanism of action

Androphy, E.

National Institutes of Health

8/15/147/31/16

Project: Research projectExploratory/Developmental Grants

Spinal Muscular Atrophy
Pharmaceutical Preparations
Proteins
Nerve Degeneration
Wnt Signaling Pathway

Development of the vaginal microbiome in young Black women

Fortenberry, J. & Forney, L.

National Institutes of Health

8/15/147/31/16

Project: Research projectHigh Priority, Short Term Project Award

Microbiota
Reproductive Health
Sexually Transmitted Diseases
Sexual Behavior
Nucleic Acid Amplification Techniques

The Role of Follicular Helper T Cells in HIV Prime Boost Vaccination

Dent, A.

National Institutes of Health

8/1/147/31/16

Project: Research projectHigh Priority, Short Term Project Award

Helper-Inducer T-Lymphocytes
Neutralizing Antibodies
HIV-1
Vaccination
Germinal Center

Graph Theoretic Analysis of Brain Networks in Cannabis Users

O'Donnell, B.

National Institutes of Health

8/1/147/31/16

Project: Research projectExploratory/Developmental Grants

Cannabis
Brain
Marijuana Abuse
Cannabinoid Receptor CB1
Personality
Solar System
Minerals
Education
Bone and Bones
Research Personnel

Drug-Drug Interactions Involving Antidiabetic Agents

Li, L. & Hennessy, S.

National Institutes of Health

7/15/146/30/18

Project: Research projectResearch Project

Drug Interactions
Hypoglycemic Agents
Pharmaceutical Preparations
Hypoglycemia
Insulin
Primary Health Care
Referral and Consultation
Veterans
Communication
Veterans Health
Vascular Diseases
Blood Vessels
Alzheimer Disease
Dementia
Cognition

IGF-1 and the initiation of non-melanoma skin cancer

Travers, J.

National Institutes of Health

7/1/146/30/18

Project: Research projectNon-HHS Research Projects

Skin Neoplasms
Somatomedins
Keratinocytes
Skin
Lasers
Frontotemporal Dementia
Caregivers
Research Personnel
Financial Support
Translational Medical Research

Follicular repressor T cells: regulation by Stat proteins and control of antibody

Dent, A.

National Institutes of Health

7/1/146/30/16

Project: Research projectExploratory/Developmental Grants

Regulatory T-Lymphocytes
T-Lymphocytes
Antibodies
Germinal Center
Proteins

Mechanism and role of selective autophagy in ethanol-induced liver injury

Yin, X.

National Institutes of Health

6/15/145/31/16

Project: Research projectExploratory/Developmental Grants

Autophagy
Ethanol
Liver
Wounds and Injuries
Alcoholic Liver Diseases
Helper-Inducer T-Lymphocytes
Cell Differentiation
Vaccination
Germinal Center
Interleukin-3

Characterization of the Cortical Salience Network in Alcoholism

Yoder, K.

National Institutes of Health

5/1/144/30/16

Project: Research projectExploratory/Developmental Grants

Alcoholic Intoxication
Alcoholism
Alcoholics
Dopamine
Alcohols

Inhibition of nNOS-PSD95 interactions: A novel approach to developing treatments

Shekhar, A.

National Institutes of Health

4/25/143/31/16

Project: Research projectExploratory/Developmental Grants

Nitric Oxide Synthase Type I
Post-Traumatic Stress Disorders
N-Methyl-D-Aspartate Receptors
Fear
Proteins

No-nonsense approach to treat myeloid malignancies with ASXL1 nonsense mutations

Xu, M. & Yang, F.

National Institutes of Health

4/3/143/31/16

Project: Research projectExploratory/Developmental Grants

Comb and Wattles
Nonsense Codon
Neoplasms
Myeloid Cells
Hematopoietic Stem Cells

HIV-Nef protein is disseminated in blood cells and causes endothelial dysfunction

Clauss, M.

National Institutes of Health

4/1/143/31/16

Project: Research projectExploratory/Developmental Grants

Human Immunodeficiency Virus nef Gene Products
Blood Cells
HIV
Blood Vessels
Endothelial Cells

LncRNA mechanism of heart failure

Chang, C.

National Institutes of Health

4/1/143/31/18

Project: Research projectResearch Project

Long Noncoding RNA
Heart Failure
Chromatin
RNA
Chromatin Immunoprecipitation

Modifying kidney injury through p53 signaling.

Dagher, P. & Sutton, T.

National Institutes of Health

4/1/143/31/18

Project: Research projectResearch Project

Acute Kidney Injury
Kidney
Wounds and Injuries
Innate Immunity
Research
behavioral science
minority
clinical psychology
transdisciplinary
apprenticeship

XIV International Symposium on Amliodosis

Benson, M.

National Institutes of Health

3/1/142/28/15

Project: Research projectConference

Amyloidosis
Familial Amyloidosis
Immunoglobulin Light Chains
Posters
Financial Management

Chemokine signaling in the transition from acute to chronic pain

White, F.

National Institutes of Health

1/1/1412/31/17

Project: Research projectNon-HHS Research Projects

Spinal Ganglia
Chemokines
Chronic Pain
Neuralgia
Wounds and Injuries
Endocardium
Heart Ventricles
Genetic Databases
Phenotype
Morphogenesis