TRANSGENIC MOUSE MODELS OF ALZHEIMERS DISEASE

Project: Research project

Description

DESCRIPTION This is an R29 proposal to use YAC based approaches to presenilin wild-type and mutant transgenics linked to FAD and to breed them to YAC FAD mutant APP transgenics already in hand and examine effects on alterations in cell biology of APP and PS-1, excitotoxicity, LTP and neuropathology.
StatusFinished
Effective start/end date4/15/973/31/04

Funding

  • National Institutes of Health: $106,993.00
  • National Institutes of Health: $80,000.00
  • National Institutes of Health: $115,728.00
  • National Institutes of Health: $102,877.00
  • National Institutes of Health
  • National Institutes of Health: $111,274.00
  • National Institutes of Health

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Flavin-Adenine Dinucleotide
Transgenic Mice
Alzheimer Disease
Presenilins
Cell Biology
Hand
Neuropathology