10-Year research update review: Psychiatric problems in children with epilepsy

Sigita Plioplys, David Dunn, Rochelle Caplan

Research output: Contribution to journalArticle

81 Citations (Scopus)

Abstract

OBJECTIVE: To critically review literature published from 1996 to 2007 on psychopathology in children with epilepsy (CWE). METHOD: Using Ovid, we searched Medline and PsychInfo databases for original studies on epidemiology, risk factors, clinical characteristics, treatment, and outcome of psychopathology in CWE, ages 0 to 18 years, using the terms "psychopathology," "emotional and behavioral problems," and "mental health problems." We selectively present the findings of studies that are clinically relevant to mental health professionals. RESULTS: Psychopathology occurs in 37% to 77% of CWE, and attention, internalizing, and thought problems may be specific to epilepsy. Cognitive and linguistic deficits, as well as family factors, have moderating effects on psychopathology in CWE. The association of epilepsy-related variables, including antiepileptic drugs, with psychopathology is inconsistent in cognitively normal CWE. Children with symptomatic epilepsy and devastating epilepsy syndromes have high rates of global developmental delay, hyperactivity, and autistic symptoms. The treatment of psychopathology in CWE integrates standard psychiatric practices. CONCLUSIONS: Epilepsy is a neuropsychiatric disorder characterized by seizures, psychopathology, cognitive, and linguistic problems. Improved early identification of CWE at risk for psychopathology, evidence-based psychiatric treatment, and multidisciplinary management strategies would advance clinical practice in this highly complex field of pediatric neuropsychiatry. Copyright 2007

Original languageEnglish
Pages (from-to)1389-1402
Number of pages14
JournalJournal of the American Academy of Child and Adolescent Psychiatry
Volume46
Issue number11
DOIs
StatePublished - Nov 2007

Fingerprint

Psychiatry
Epilepsy
Psychopathology
Research
Linguistics
Mental Health
Neuropsychiatry
Anticonvulsants
Epidemiology
Databases
Pediatrics

Keywords

  • Antiepileptic drugs
  • Children
  • Cognitive functioning
  • Epilepsy
  • Family factors
  • Psychopathology

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Developmental and Educational Psychology

Cite this

10-Year research update review : Psychiatric problems in children with epilepsy. / Plioplys, Sigita; Dunn, David; Caplan, Rochelle.

In: Journal of the American Academy of Child and Adolescent Psychiatry, Vol. 46, No. 11, 11.2007, p. 1389-1402.

Research output: Contribution to journalArticle

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