Find Publications

Zinc for infection prevention in sickle cell anemia (zips): Study protocol for a randomized placebo-controlled trial in ugandan children with sickle cell anemia

Datta, D., Namazzi, R., Conroy, A. L., Cusick, S. E., Hume, H. A., Tagoola, A., Ware, R. E., Opoka, R. O. & John, C., Jul 26 2019, In : Trials. 20, 1, 460.

Research output: Contribution to journalArticle

Open Access
Sickle Cell Anemia
Zinc
Randomized Controlled Trials
Placebos
Infection
130 Citations (Scopus)

Zinc-induced copper deficiency: A report of three cases initially recognized on bone marrow examination

Willis, M., Monaghan, S. A., Miller, M. L., McKenna, R. W., Perkins, W. D., Levinson, B. S., Bhushan, V. & Kroft, S. H., Jan 1 2005, In : American Journal of Clinical Pathology. 123, 1, p. 125-131 7 p.

Research output: Contribution to journalArticle

Open Access
Bone Marrow Examination
Neutropenia
Zinc
Copper
Anemia
51 Citations (Scopus)

Zinc inhibition of renin and the protease from human immunodeficiency virus type 1

Zhang, Z-Y., Reardon, I. M., Hui, J. O., O'Connell, K. L., Poorman, R. A., Tomasselli, A. G. & Heinrikson, R. L., 1991, In : Biochemistry. 30, 36, p. 8717-8721 5 p.

Research output: Contribution to journalArticle

Viruses
Renin
Aspartic Acid Proteases
HIV-1
Zinc
23 Citations (Scopus)

Zinc oxide nanoparticles-induced reactive oxygen species promotes multimodal cyto- and epigenetic toxicity

Choudhury, S. R., Ordaz, J., Lo, C. L., Damayanti, N. P., Zhou, F. & Irudayaraj, J., Mar 1 2017, In : Toxicological Sciences. 156, 1, p. 261-274 14 p.

Research output: Contribution to journalArticle

Zinc Oxide
Epigenomics
Nanoparticles
Toxicity
Reactive Oxygen Species
6 Citations (Scopus)

ZLM-7 exhibits anti-angiogenic effects via impaired endothelial cell function and blockade of VEGF/VEGFR-2 signaling

Su, M., Huang, J., Li, J., Qin, X., Tang, X., Jin, F., Chen, S., Jiang, C., Zou, Z., Peng, K., Nuruzzaman, M., Zhang, J-T., Luo, J., Liu, S. & Luo, Z., Jan 1 2016, In : Oncotarget. 7, 14, p. 19018-19030 13 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor Receptor-2
Vascular Endothelial Growth Factor A
Endothelial Cells
Chorioallantoic Membrane
Cell Hypoxia

Zn2+-dependent single-stranded DNA binding and DNA replication activities in replication protein A

Lu, M., Kwak, I. J., Kim, A., Kim, D. K., Lee, S-H. & Park, J. S., Dec 2009, In : Bulletin of the Korean Chemical Society. 30, 12, p. 2867-2868 2 p.

Research output: Contribution to journalArticle

Replication Protein A
Single-Stranded DNA
DNA
Oxidation-Reduction

Zoledronate and Raloxifene combination therapy enhances material and mechanical properties of diseased mouse bone

Powell, K. M., Skaggs, C., Pulliam, A., Berman, A., Allen, M. & Wallace, J. M., Oct 1 2019, In : Bone. 127, p. 199-206 8 p.

Research output: Contribution to journalArticle

zoledronic acid
Bone Diseases
Bone and Bones
Genotype
Therapeutics
7 Citations (Scopus)

Zoledronate treatment has different effects in mouse strains with contrasting baseline bone mechanical phenotypes

Aref, M. W., McNerny, E. M. B., Brown, D., Jepsen, K. J. & Allen, M., Jul 20 2016, (Accepted/In press) In : Osteoporosis International. p. 1-7 7 p.

Research output: Contribution to journalArticle

zoledronic acid
Phenotype
Bone and Bones
Genotype
Pharmaceutical Preparations
22 Citations (Scopus)

Zonal distribution of protein-acetaldehyde adducts in the liver of rats fed alcohol for long periods

Lin, R. C., Zhou, F., Fillenwarth, M. J. & Lumeng, L., Oct 1993, In : Hepatology. 18, 4, p. 864-869 6 p.

Research output: Contribution to journalArticle

Acetaldehyde
Alcohols
Liver
Proteins
Peroxidase
61 Citations (Scopus)
Tumors
Prostate
Adenocarcinoma
Neoplasms
Surgical Pathology
10 Citations (Scopus)

Zonulae occludentes of the rat nephron under conditions of experimental expansion of blood and/or fluid volume

Evan, A., Baker, J. T. & Bengele, H. H., 1976, In : Anatomical Record. 186, 2, p. 139-150 12 p.

Research output: Contribution to journalArticle

nephrons
tight junctions
Tight Junctions
Nephrons
rats
122 Citations (Scopus)

Zosuquidar, a novel modulator of P-glycoprotein, does not improve the outcome of older patients with newly diagnosed acute myeloid leukemia: A randomized, placebo-controlled trial of the Eastern Cooperative Oncology Group 3999

Cripe, L., Uno, H., Paietta, E. M., Litzow, M. R., Ketterling, R. P., Bennett, J. M., Rowe, J. M., Lazarus, H. M., Luger, S. & Tallman, M. S., Nov 18 2010, In : Blood. 116, 20, p. 4077-4085 9 p.

Research output: Contribution to journalArticle

Oncology
P-Glycoprotein
Acute Myeloid Leukemia
Modulators
Randomized Controlled Trials
8 Citations (Scopus)

Z-stent for malignant esophageal obstruction

Rahmani, E. Y., Rex, D. & Lehman, G., 1999, In : Gastrointestinal Endoscopy Clinics of North America. 9, 3, p. 395-402 8 p.

Research output: Contribution to journalArticle

Stents
Esophageal Fistula
Prostheses and Implants
Metals
35 Citations (Scopus)

Δ40 isoform of p53 controls β-cell proliferation and glucose homeostasis in mice

Hinault, C., Kawamori, D., Liew, C. W., Maier, B., Hu, J., Keller, S. R., Mirmira, R., Scrable, H. & Kulkarni, R. N., Apr 2011, In : Diabetes. 60, 4, p. 1210-1222 13 p.

Research output: Contribution to journalArticle

Protein Isoforms
Homeostasis
Cell Proliferation
Glucose
p53 Genes
46 Citations (Scopus)

ΔF508 GENE DELETION IN CYSTIC FIBROSIS IN SOUTHERN EUROPE

Estivill, X., Casals, T., Morral, N., Chillon, M., Bosch, A., Nunes, V., Gasparini, P., Seia, A., Pignatti, P. F., Novelli, G., Dallapiccola, B., Fernandez, E., Benitez, J. & Williamson, R., Dec 9 1989, In : The Lancet. 334, 8676, p. 1404 1 p.

Research output: Contribution to journalArticle

Chromosomes, Human, 19-20
Chromosome Deletion
Gene Deletion
Cystic Fibrosis
Spain
24 Citations (Scopus)

ΔNp53 or p44: Priming the p53 pump

Scrable, H., Sasaki, T. & Maier, B., May 2005, In : International Journal of Biochemistry and Cell Biology. 37, 5 SPEC. ISS., p. 913-919 7 p.

Research output: Contribution to journalArticle

Protein Isoforms
Pumps
Transcription Factors
Genes
Proteins
35 Citations (Scopus)

Δnp63α regulates keratinocyte proliferation by controlling PTEN expression and localization

Leonard, M. K., Kommagani, R., Payal, V., Mayo, L., Shamma, H. N. & Kadakia, M. P., Dec 2011, In : Cell Death and Differentiation. 18, 12, p. 1924-1933 10 p.

Research output: Contribution to journalArticle

Skin Neoplasms
Keratinocytes
Chromosomes, Human, Pair 10
Oncogenes
Phosphoric Monoester Hydrolases
34 Citations (Scopus)

α1-antitrypsin deficiency-associated liver disease progresses slowly in some children

Volpert, D., Molleston, J. & Perlmutter, D. H., 2000, In : Journal of Pediatric Gastroenterology and Nutrition. 31, 3, p. 258-263 6 p.

Research output: Contribution to journalArticle

liver diseases
Liver Diseases
portal hypertension
Portal Hypertension
Fibrosis
173 Citations (Scopus)

α-1 antitrypsin inhibits caspase-3 activity, preventing lung endothelial cell apoptosis

Petrache, I., Fijalkowska, I., Medler, T. R., Skirball, J., Cruz, P., Zhen, L., Petrache, H. I., Flotte, T. R. & Tuder, R. M., Oct 2006, In : American Journal of Pathology. 169, 4, p. 1155-1166 12 p.

Research output: Contribution to journalArticle

Caspase 3
Emphysema
Endothelial Cells
Apoptosis
Lung
34 Citations (Scopus)

α1-antitrypsin modulates lung endothelial cell inflammatory responses to TNF-α

Lockett, A., Kimani, S., Ddungu, G., Wrenger, S., Tuder, R. M., Janciauskiene, S. M. & Petrache, I., Jul 2013, In : American Journal of Respiratory Cell and Molecular Biology. 49, 1, p. 143-150 8 p.

Research output: Contribution to journalArticle

Endothelial cells
Endothelial Cells
Lung
Amplification
Inflammation
10 Citations (Scopus)

α2-adrenoceptor subsensitivity in mesenteric vascular bed of cholestatic rats: The role of nitric oxide and endogenous opioids

Borhani, A. A., Houshmand, G., Samini, M., Namiranian, K., Hajrasouliha, A. R., Tavakoli, S., Ebrahimi, F. & Dehpour, A. R., May 9 2005, In : European Journal of Pharmacology. 514, 2-3, p. 183-189 7 p.

Research output: Contribution to journalArticle

Clonidine
Adrenergic Receptors
Opioid Analgesics
Blood Vessels
Nitric Oxide
16 Citations (Scopus)

α2-Macroglobulin, lipoprotein receptor-related protein and lipoprotein receptor-associated protein and the genetic risk for developing Alzheimer's disease

Depboylu, C., Lohmüller, F., Du, Y., Riemenschneider, M., Kurz, A., Gasser, T., Müller, U. & Dodel, R. C., Jun 12 2006, In : Neuroscience Letters. 400, 3, p. 187-190 4 p.

Research output: Contribution to journalArticle

Lipoprotein Receptors
Macroglobulins
Alzheimer Disease
Proteins
Apolipoprotein E4
64 Citations (Scopus)

α2 Macroglobulin and the risk of Alzheimer's disease

Dodel, R. C., Du, Y., Bales, K. R., Gao, F., Eastwood, B., Glazier, B., Zimmer, R., Cordell, B., Hake, A., Evans, R., Gallagher-Thompson, D., Thompson, L. W., Tinklenberg, J. R., Pfefferbaum, A., Sullivan, E. V., Yesavage, J., Altstiel, L., Gasser, T., Farlow, M., Murphy, G. M. & 1 others, Paul, S. M., Jan 25 2000, In : Neurology. 54, 2, p. 438-442 5 p.

Research output: Contribution to journalArticle

Macroglobulins
Alzheimer Disease
Gene Frequency
Genes
Odds Ratio
120 Citations (Scopus)

α2-Macroglobulin as a β-amyloid peptide-binding plasma protein

Du, Y., Ni, B., Glinn, M., Dodel, R. C., Bales, K. R., Zhang, Z., Hyslop, P. A. & Paul, S. M., Jul 1997, In : Journal of Neurochemistry. 69, 1, p. 299-305 7 p.

Research output: Contribution to journalArticle

Macroglobulins
Amyloid
Blood Proteins
Carrier Proteins
Peptides
100 Citations (Scopus)

α2-macroglobulin attenuates β-amyloid peptide 1-40 fibril formation and associated neurotoxicity of cultured fetal rat cortical neurons

Du, Y., Bales, K. R., Dodel, R. C., Liu, X., Glinn, M. A., Horn, J. W., Little, S. P. & Paul, S. M., Mar 1998, In : Journal of Neurochemistry. 70, 3, p. 1182-1188 7 p.

Research output: Contribution to journalArticle

Macroglobulins
Amyloid
Neurons
Rats
Peptides
164 Citations (Scopus)

α5β1 integrin as a cellular coreceptor for human parvovirus B19: Requirement of functional activation of β1 integrin for viral entry

Weigel-Kelley, K. A., Yoder, M. & Srivastava, A., Dec 1 2003, In : Blood. 102, 12, p. 3927-3933 7 p.

Research output: Contribution to journalArticle

Human Parvovirus B19
Parvovirus
Integrins
Chemical activation
Antigens
2 Citations (Scopus)

α5β1 integrin mediates pulmonary epithelial cyst formation

Legan, S. K., Lee, D. D. & Schwarz, M., Jun 1 2017, In : Developmental Dynamics. 246, 6, p. 475-484 10 p.

Research output: Contribution to journalArticle

Integrins
Cysts
Lung
Epithelial Cells
Cell Shape
58 Citations (Scopus)

α9β1: A novel osteoclast integrin that regulates osteoclast formation and function

Rao, H., Lu, G., Kajiya, H., Garcia-Palacios, V., Kurihara, N., Anderson, J., Patrene, K., Sheppard, D., Blair, H. C., Windle, J. J., Choi, S. J. & Roodman, G. D., Oct 2006, In : Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 21, 10, p. 1657-1665 9 p.

Research output: Contribution to journalArticle

Osteoclasts
Integrins
Disintegrins
Bone Resorption
Spine
77 Citations (Scopus)

α-Actinin: A direct link between actin and integrins

Pavalko, F., Otey, C. A., Simon, K. O. & Burridge, K., 1991, In : Biochemical Society Transactions. 19, 4, p. 1065-1069 5 p.

Research output: Contribution to journalArticle

Actinin
Integrins
Actins
8 Citations (Scopus)

α-adrenergic agonists’ effects on ocular hemodynamics

Harris, A., Caldemeyer, K. S., Mansberger, S. L. & Martin, B. J., 1995, In : Journal of Glaucoma. 4, p. S19-S23

Research output: Contribution to journalArticle

Adrenergic alpha-Agonists
Adrenergic Agents
Hemodynamics
91 Citations (Scopus)

α-Adrenergic blockade in children with neuropathic and nonneuropathic voiding dysfunction

Austin, P. F., Homsy, Y. L., Masel, J. L., Cain, M. P., Casale, A. J. & Rink, R. C., Sep 1999, In : Journal of Urology. 162, 3 II, p. 1064-1067 4 p.

Research output: Contribution to journalArticle

Adrenergic Agents
Urinary Bladder
Meningomyelocele
Neurogenic Urinary Bladder
Urine
50 Citations (Scopus)

α Adrenergic reduction of cyclic adenosine monophosphate concentrations in rat myocardium

Watanabe, A. M., Hathaway, D. R., Besch, H. R., Farmer, B. B. & Harris, R., Dec 1 1977, In : Circulation Research. 40, 6, p. 596-602 7 p.

Research output: Contribution to journalArticle

Cyclic AMP
Adrenergic Agents
Myocardium
Phenylephrine
Adrenergic Receptors
13 Citations (Scopus)

α-Adrenergic Vasoconstrictor Tone Limits Right Coronary Blood Flow in Exercising Dogs

Zong, P., Sun, W., Setty, S., Tune, J. & Downey, H. F., Apr 2004, In : Experimental Biology and Medicine. 229, 4, p. 312-322 11 p.

Research output: Contribution to journalArticle

Vasoconstrictor Agents
Adrenergic Agents
Blood
Dogs
Hyperemia
14 Citations (Scopus)

α-adrenoceptor-mediated coronary vasoconstriction is augmented during exercise in experimental diabetes mellitus

Setty, S., Sun, W., Martinez, R., Downey, H. F. & Tune, J., Jul 2004, In : Journal of Applied Physiology. 97, 1, p. 431-438 8 p.

Research output: Contribution to journalArticle

Experimental Diabetes Mellitus
Vasoconstriction
Adrenergic Receptors
Dogs
Alloxan
77 Citations (Scopus)

α-Adrenoceptor stimulation and blockade modulates cesium-induced early afterdepolarizations and ventricular tachyarrhythmias in dogs

Ben-David, J. & Zipes, D. P., 1990, In : Circulation. 82, 1, p. 225-233 9 p.

Research output: Contribution to journalArticle

Cesium
Tachycardia
Adrenergic Receptors
Dogs
Phentolamine
36 Citations (Scopus)

αB-crystallin, an effector of unfolded protein response, confers anti-VEGF resistance to breast cancer via maintenance of intracrine VEGF in endothelial cells

Ruan, Q., Han, S., Jiang, W. G., Boulton, M. E., Chen, Z. J., Law, B. K. & Cai, J., Dec 2011, In : Molecular Cancer Research. 9, 12, p. 1632-1643 12 p.

Research output: Contribution to journalArticle

Unfolded Protein Response
Crystallins
Vascular Endothelial Growth Factor A
Endothelial Cells
Maintenance
16 Citations (Scopus)

α-COP binding to the survival motor neuron protein SMN is required for neuronal process outgrowth

Li, H., Custer, S. K., Gilson, T., Hao, L. T., Beattie, C. E. & Androphy, E., 2015, In : Human Molecular Genetics. 24, 25, p. 7295-7307 13 p.

Research output: Contribution to journalArticle

Motor Neurons
Spinal Muscular Atrophy
Coat Protein Complex I
Zebrafish
Proteins
41 Citations (Scopus)

α-Lipoic acid attenuates vascular calcification via reversal of mitochondrial function and restoration of Gas6/Axl/Akt survival pathway

Kim, H., Kim, H. J., Lee, K., Kim, J. M., Kim, H. S., Kim, J. R., Ha, C. M., Choi, Y. K., Lee, S. J., Kim, J. Y., Harris, R., Jeong, D. & Lee, I. K., Feb 2012, In : Journal of Cellular and Molecular Medicine. 16, 2, p. 273-286 14 p.

Research output: Contribution to journalArticle

Vascular Calcification
Thioctic Acid
Vascular Smooth Muscle
Smooth Muscle Myocytes
Survival
25 Citations (Scopus)

α-methylacyl-CoA racemase (P504S)/34βE12/p63 triple cocktail stain in prostatic adenocarcinoma after hormonal therapy

Sung, M. T., Jiang, Z., Montironi, R., MacLennan, G. T., Mazzucchelli, R. & Cheng, L., Feb 2007, In : Human Pathology. 38, 2, p. 332-341 10 p.

Research output: Contribution to journalArticle

Racemases and Epimerases
Coenzyme A
Adenocarcinoma
Coloring Agents
Prostate
25 Citations (Scopus)

α-methylacyl-CoA racemase spliced variants and their expression in normal and malignant prostate tissues

Ouyang, B., Leung, Y. K., Wang, V., Chung, E., Levin, L., Bracken, B., Cheng, L. & Ho, S. M., Jan 2011, In : Urology. 77, 1

Research output: Contribution to journalArticle

Racemases and Epimerases
Coenzyme A
Prostate
Biomarkers
Molecular Cloning
22 Citations (Scopus)

α-methylacyl coenzyme A racemase, Ki-67, and topoisomerase IIα in cystoprostatectomies with incidental prostate cancer

Santinelli, A., Mazzucchelli, R., Barbisan, F., Lopez-Beltran, A., Cheng, L., Scarpelli, M. & Montironi, R., Oct 2007, In : American Journal of Clinical Pathology. 128, 4, p. 657-664 8 p.

Research output: Contribution to journalArticle

Racemases and Epimerases
Type II DNA Topoisomerase
Coenzyme A
Prostatectomy
Prostate
68 Citations (Scopus)

α-satellite DNA and vector composition influence rates of human artificial chromosome formation

Grimes, B., Rhoades, A. A. & Willard, H. F., 2002, In : Molecular Therapy. 5, 6, p. 798-805 8 p.

Research output: Contribution to journalArticle

Human Artificial Chromosomes
Satellite DNA
Chromosomes, Human, Pair 17
Chromosome Structures
Chromosomes, Human, Pair 21
51 Citations (Scopus)

α-SNS Produces the Slow TTX-Resistant Sodium Current in Large Cutaneous Afferent DRG Neurons

Renganathan, M., Cummins, T., Hormuzdiar, W. N. & Waxman, S. G., 2000, In : Journal of Neurophysiology. 84, 2, p. 710-718 9 p.

Research output: Contribution to journalArticle

Tetrodotoxin
Spinal Ganglia
Sensory Receptor Cells
Sodium
Neurons
99 Citations (Scopus)

α-Synuclein maps to a quantitative trait locus for alcohol preference and is differentially expressed in alcohol-preferring and -nonpreferring rats

Liang, T., Spence, J., Liu, L., Strother, W. N., Chang, H. W., Ellison, J. A., Lumeng, L., Li, T. K., Foroud, T. & Carr, L. G., Apr 15 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 8, p. 4690-4695 6 p.

Research output: Contribution to journalArticle

Synucleins
Quantitative Trait Loci
Alcohols
3' Untranslated Regions
Hippocampus

α-Synuclein RT-QuIC assay in cerebrospinal fluid of patients with dementia with Lewy bodies

Bongianni, M., Ladogana, A., Capaldi, S., Klotz, S., Baiardi, S., Cagnin, A., Perra, D., Fiorini, M., Poleggi, A., Legname, G., Cattaruzza, T., Janes, F., Tabaton, M., Ghetti, B., Monaco, S., Kovacs, G. G., Parchi, P., Pocchiari, M. & Zanusso, G., Oct 1 2019, In : Annals of Clinical and Translational Neurology. 6, 10, p. 2120-2126 7 p.

Research output: Contribution to journalArticle

Open Access
Synucleins
Lewy Body Disease
Cerebrospinal Fluid
Pathology
Neurodegenerative Diseases
59 Citations (Scopus)

β1 integrin and organized actin filaments facilitate cardiomyocytes-specific RhoA-dependent activation of the skeletal α-actin promoter

Wei, L., Wang, L., Carson, J. A., Agan, J. E., Imanaka-Yoshida, K. & Schwartz, R. J., 2001, In : FASEB Journal. 15, 3, p. 785-796 12 p.

Research output: Contribution to journalArticle

integrins
microfilaments
Actin Cytoskeleton
Cardiac Myocytes
Integrins
102 Citations (Scopus)

β1 integrin expression by podocytes is required to maintain glomerular structural integrity

Pozzi, A., Jarad, G., Moeckel, G. W., Coffa, S., Zhang, X., Gewin, L., Eremina, V., Hudson, B. G., Borza, D. B., Harris, R. C., Holzman, L. B., Phillips, C., Fassler, R., Quaggin, S. E., Miner, J. H. & Zent, R., Apr 15 2008, In : Developmental Biology. 316, 2, p. 288-301 14 p.

Research output: Contribution to journalArticle

Podocytes
Integrins
Glomerular Filtration Barrier
Kidney Glomerulus
Glomerular Basement Membrane
159 Citations (Scopus)

β2-adrenergic receptor-stimulated increase in cAMP in rat heart cells is not coupled to changes in Ca2+ dynamics, contractility, or phospholamban phosphorylation

Xiao, R. P., Hohl, C., Altschuld, R., Jones, L., Livingston, B., Ziman, B., Tantini, B. & Lakatta, E. G., Jul 22 1994, In : Journal of Biological Chemistry. 269, 29, p. 19151-19156 6 p.

Research output: Contribution to journalArticle

Phosphorylation
Adrenergic Receptors
Rats
Muscle Cells
Membranes
14 Citations (Scopus)

β2-Microglobulin increases the expression of vascular cell adhesion molecule on human synovial fibroblasts

Jaradat, M. I., Schnizlein-Bick, C. T., Singh, G. K. & Moe, S., 2001, In : Kidney International. 59, 5, p. 1951-1959 9 p.

Research output: Contribution to journalArticle

Vascular Cell Adhesion Molecule-1
Fibroblasts
Advanced Glycosylation End Products
Amyloidosis
Northern Blotting
23 Citations (Scopus)

β2-microglobulin induces apoptosis in HL-60 human leukemia cell line and its multidrug resistant variants overexpressing MRP1 but lacking Bax or overexpressing P-glycoprotein

Wu, C. H., Rastegar, M., Gordon, J. & Safa, A., Oct 25 2001, In : Oncogene. 20, 48, p. 7006-7020 15 p.

Research output: Contribution to journalArticle

HL-60 Cells
P-Glycoprotein
Leukemia
Apoptosis
Cell Line