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97 Citations (Scopus)

Action of manganese ions and tetrodotoxin on atrioventricular nodal transmembrane potentials in isolated rabbit hearts.

Zipes, D. P. & Mendez, C., Apr 1973, In : Circulation Research. 32, 4, p. 447-454 8 p.

Research output: Contribution to journalArticle

Chemical Depression
Heart Conduction System
Tetrodotoxin
Manganese
Membrane Potentials
439 Citations (Scopus)

Action of secretagogues on a new preparation of functionally intact, isolated pancreatic acini.

Williams, J. A., Korc, M. & Dormer, R. L., Nov 1978, In : The American journal of physiology. 235, 5, p. 517-524 8 p.

Research output: Contribution to journalArticle

Amylases
Ceruletide
Pancreas
Acinar Cells
Cholinergic Agents
24 Citations (Scopus)

Action of zolpidem on responses to GABA in relation to mRNAs for GABA(A) receptor alpha subunits within single cells: Evidence for multiple functional GABA(A) isoreceptors on individual neurons

Criswell, H. E., McCown, T. J., Moy, S. S., Oxford, G. S., Mueller, R. A., Morrow, A. L. & Breese, G. R., 1997, In : Neuropharmacology. 36, 11-12, p. 1641-1652 12 p.

Research output: Contribution to journalArticle

GABA-A Receptors
gamma-Aminobutyric Acid
Neurons
Messenger RNA
zolpidem
13 Citations (Scopus)

Action potential duration and QT interval during pinacidil infusion in isolated rabbit hearts

Wu, S., Hayashi, H., Lin, S-F. & Chen, P-S., Aug 2005, In : Journal of Cardiovascular Electrophysiology. 16, 8, p. 872-878 7 p.

Research output: Contribution to journalArticle

Pinacidil
KATP Channels
Action Potentials
Epicardial Mapping
Rabbits
21 Citations (Scopus)

Action potential duration restitution and ventricular fibrillation due to rapid focal excitation

Swissa, M., Qu, Z., Ohara, T., Lee, M. H., Lin, S-F., Garfinkel, A., Karagueuzian, H. S., Weiss, J. N. & Chen, P-S., 2002, In : American Journal of Physiology - Heart and Circulatory Physiology. 282, 5 51-5

Research output: Contribution to journalArticle

Ventricular Fibrillation
Aconitine
Action Potentials
Ventricular Tachycardia
Heart Ventricles
17 Citations (Scopus)
Cortactin
Actin-Related Protein 2-3 Complex
Protein-Tyrosine Kinases
Actins
Actin Cytoskeleton
93 Citations (Scopus)

Actions of 3,4-methylenedioxymethamphetamine (MDMA) on cerebral dopaminergic, serotonergic and cholinergic neurons

Gudelsky, G. A. & Yamamoto, B., Aug 2008, In : Pharmacology Biochemistry and Behavior. 90, 2, p. 198-207 10 p.

Research output: Contribution to journalReview article

Serotonergic Neurons
N-Methyl-3,4-methylenedioxyamphetamine
Cholinergic Neurons
Dopaminergic Neurons
Cholinergic Agents
33 Citations (Scopus)

Actions of bisphosphonates in animal models of breast cancer

Padelecki, S. S. & Guise, T., 2002, In : Breast Cancer Research. 4, 1, p. 35-41 7 p.

Research output: Contribution to journalArticle

Diphosphonates
Animal Models
Breast Neoplasms
Bone and Bones
Neoplasm Metastasis
16 Citations (Scopus)

Actions of hematopoietic colony-stimulating factors in vivo and in vitro.

Broxmeyer, H. & Williams, D. E., 1987, In : Pathology and immunopathology research. 6, 3, p. 207-220 14 p.

Research output: Contribution to journalArticle

Colony-Stimulating Factors
Hematopoiesis
Neoplasms
In Vitro Techniques
5 Citations (Scopus)

Actions of H-subunit ferritin and lactoferrin as suppressor molecules of myelopoiesis in vitro and in vivo

Broxmeyer, H., Mantel, C., Gentile, P., Srivastava, C., Miyazawa, K., Zucali, J. R., Rado, T. A., Levi, S. & Arosio, P., 1991, Current Studies in Hematology and Blood Transfusion. 58 ed. p. 178-181 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Chemical Depression
Myelopoiesis
Apoferritins
Mononuclear Leukocytes
Lactoferrin
11 Citations (Scopus)

Actions of the Clostridium botulinum binary toxin on the structure and function of Y-1 adrenal cells

Zepeda, H., Considine, R., Smith, H. L., Sherwin, J. R., Ohishi, I. & Simpson, L. L., 1988, In : Journal of Pharmacology and Experimental Therapeutics. 246, 3, p. 1183-1189 7 p.

Research output: Contribution to journalArticle

Botulinum Toxins
NAD
Adenosine Diphosphate
Actins
Adenosine Monophosphate
59 Citations (Scopus)
Peroxisome Proliferator-Activated Receptors
AMP-Activated Protein Kinases
Hepatocellular Carcinoma
rosiglitazone
Metformin
19 Citations (Scopus)

Activated H-Ras regulates hematopoietic cell survival by modulating Survivin

Fukuda, S. & Pelus, L., Oct 15 2004, In : Biochemical and Biophysical Research Communications. 323, 2, p. 636-644 9 p.

Research output: Contribution to journalArticle

Interleukin-3
Cell Survival
Intercellular Signaling Peptides and Proteins
Cells
S Phase
42 Citations (Scopus)

Activated in prostate cancer: A PDZ domain-containing protein highly expressed in human primary prostate tumors

Chaib, H., Rubin, M. A., Mucci, N. R., Li, L., Taylor, J. M. G., Day, M. L., Rhim, J. S. & Macoska, J. A., Mar 15 2001, In : Cancer Research. 61, 6, p. 2390-2394 5 p.

Research output: Contribution to journalArticle

PDZ Domains
Prostate
Prostatic Neoplasms
Prostatic Intraepithelial Neoplasia
Neoplasms
36 Citations (Scopus)

Activated K-ras and INK4a/Arf deficiency cooperate during the development of pancreatic cancer by activation of notch and NF-κB signaling pathways

Wang, Z., Banerjee, S., Ahmad, A., Li, Y., Azmi, A. S., Gunn, J. R., Kong, D., Bao, B., Ali, S., Gao, J., Mohammad, R. M., Miele, L., Korc, M. & Sarkar, F. H., 2011, In : PLoS One. 6, 6, e20537.

Research output: Contribution to journalArticle

pancreatic neoplasms
adenocarcinoma
Pancreatic Neoplasms
Tumors
Assays
38 Citations (Scopus)

Activated K-Ras and INK4a/Arf deficiency promote aggressiveness of pancreatic cancer by induction of EMT consistent with cancer stem cell phenotype

Wang, Z., Ali, S., Banerjee, S., Bao, B., Li, Y., Azmi, A. S., Korc, M. & Sarkar, F. H., Mar 2013, In : Journal of Cellular Physiology. 228, 3, p. 556-562 7 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Neoplastic Stem Cells
Stem cells
Pancreatic Neoplasms
Tumors

Activated K-Ras and INK4a/Arf deficiency promote aggressiveness of pancreatic cancer by induction of EMT consistent with cancer stem cell phenotype

Wang, Z., Ali, S., Banerjee, S., Bao, B., Li, Y., Azmi, A. S., Korc, M. & Sarkar, F. H., 2014, In : Journal of Cellular Physiology. 229, 8, p. 1118 1 p.

Research output: Contribution to journalArticle

Stem cells
3 Citations (Scopus)

Activated leukocyte cell adhesion molecule (ALCAM or CD166) modulates bone phenotype and hematopoiesis

Hooker, R. A., Chitteti, B. R., Egan, P. H., Cheng, Y. H., Himes, E. R., Meijome, T., Srour, E., Fuchs, R. K. & Kacena, M., 2015, In : Journal of Musculoskeletal Neuronal Interactions. 15, 1, p. 83-94 12 p.

Research output: Contribution to journalArticle

Activated-Leukocyte Cell Adhesion Molecule
Hematopoiesis
Osteoblasts
Phenotype
Bone and Bones
3 Citations (Scopus)
Leukocyte Chemotaxis
Chemokine Receptors
Monocytes
Obesity
Inflammation
83 Citations (Scopus)

Activated or dominant inhibitory mutants of Rap1A decrease the oxidative burst of Epstein-Barr virus-transformed human B lymphocytes

Maly, F. E., Quilliam, L., Dorseuil, O., Der, C. J. & Bokoch, G. M., Jul 22 1994, In : Journal of Biological Chemistry. 269, 29, p. 18743-18746 4 p.

Research output: Contribution to journalArticle

Respiratory Burst
Lymphocytes
NADPH Oxidase
Guanosine Triphosphate
Human Herpesvirus 4
5 Citations (Scopus)
ADAM Proteins
Tissue Inhibitor of Metalloproteinase-3
Pericytes
Kidney Diseases
Blood Vessels
104 Citations (Scopus)

Activated protein C ameliorates LPS-induced acute kidney injury and downregulates renal INOS and angiotensin 2

Gupta, A., Rhodes, G. J., Berg, D. T., Gerlitz, B., Molitoris, B. & Grinnell, B. W., Jul 2007, In : American Journal of Physiology - Renal Physiology. 293, 1

Research output: Contribution to journalArticle

Angiotensins
Protein C
Acute Kidney Injury
Lipopolysaccharides
Down-Regulation
25 Citations (Scopus)

Activated protein C and acute kidney injury: Selective targeting of PAR-1

Gupta, A., Williams, M. D., Macias, W. L., Molitoris, B. & Grinnell, B. W., 2009, In : Current Drug Targets. 10, 12, p. 1212-1226 15 p.

Research output: Contribution to journalArticle

PAR-1 Receptor
Protein C
Acute Kidney Injury
Protein C Deficiency
Tissue Survival
479 Citations (Scopus)

Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective

Cheng, T., Liu, D., Griffin, J. H., Fernández, J. A., Castellino, F., Rosen, E., Fukudome, K. & Zlokovic, B. V., Mar 1 2003, In : Nature Medicine. 9, 3, p. 338-342 5 p.

Research output: Contribution to journalArticle

Protein C
Endothelium
Brain
Apoptosis
PAR-1 Receptor
128 Citations (Scopus)

Activated ras and ret oncogenes induce over-expression of c-met (hepatocyte growth factor receptor) in human thyroid epithelial cells

Ivan, M., Bond, J. A., Prat, M., Comoglio, P. M. & Wynford-Thomas, D., 1997, In : Oncogene. 14, 20, p. 2417-2423 7 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-met
ras Genes
Oncogenes
Thyroid Gland
Epithelium
3 Citations (Scopus)
Hemorrhage
recombinant FVIIa
1 Citation (Scopus)

Activating KRAS mutations in arteriovenous malformations of the brain: frequency and clinicopathologic correlation

Priemer, D. S., Vortmeyer, A., Zhang, S., Chang, H. Y., Curless, K. L. & Cheng, L., Jul 1 2019, In : Human pathology. 89, p. 33-39 7 p.

Research output: Contribution to journalArticle

Arteriovenous Malformations
Mutation
Brain
Dura Mater
Inborn Genetic Diseases
20 Citations (Scopus)

Activating PTPN11 mutants promote hematopoietic progenitor cell-cycle progression and survival

Yang, Z., Li, Y., Yin, F. & Chan, R., Oct 2008, In : Experimental Hematology. 36, 10, p. 1285-1296 12 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Cell Survival
Cell Cycle
Juvenile Myelomonocytic Leukemia
Apoptosis Regulatory Proteins
976 Citations (Scopus)

Activating Smoothened mutations in sporadic basal-cell carcinoma

Xie, J., Murone, M., Luoh, S. M., Ryan, A., Gu, Q., Zhang, C., Bonifas, J. M., Lam, C. W., Hynes, M., Goddard, A., Rosenthal, A., Epstein, E. H. & De Sauvage, F. J., Jan 1 1998, In : Nature. 391, 6662, p. 90-92 3 p.

Research output: Contribution to journalArticle

Basal Cell Carcinoma
Basal Cell Nevus Syndrome
Mutation
Hedgehogs
Genes
330 Citations (Scopus)

Activating Transcription Factor 3 Is Integral to the Eukaryotic Initiation Factor 2 Kinase Stress Response

Jiang, H. Y., Wek, S. A., McGrath, B. C., Lu, D., Hai, T., Harding, H. P., Wang, X., Ron, D., Cavener, D. R. & Wek, R., Feb 2004, In : Molecular and Cellular Biology. 24, 3, p. 1365-1377 13 p.

Research output: Contribution to journalArticle

Activating Transcription Factor 3
Eukaryotic Initiation Factor-2
Phosphotransferases
Leucine Zippers
Endoplasmic Reticulum Stress
44 Citations (Scopus)

Activating transcription factor 4 regulates osteoclast differentiation in mice

Cao, H., Yu, S., Yao, Z., Galson, D. L., Jiang, Y., Zhang, X., Fan, J., Lu, B., Guan, Y., Luo, M., Lai, Y., Zhu, Y., Kurihara, N., Patrene, K., Roodman, G. D. & Xiao, G., Aug 2 2010, In : Journal of Clinical Investigation. 120, 8, p. 2755-2766 12 p.

Research output: Contribution to journalArticle

Activating Transcription Factor 4
Osteoclasts
Macrophage Colony-Stimulating Factor
Osteogenesis
Transcription Factors
68 Citations (Scopus)

Activation and inactivation of the voltage-gated sodium channel: Role of segment S5 revealed by a novel hyperkalaemic periodic paralysis mutation

Bendahhou, S., Cummins, T., Tawil, R., Waxman, S. G. & Ptácek, L. J., Jun 15 1999, In : Journal of Neuroscience. 19, 12, p. 4762-4771 10 p.

Research output: Contribution to journalArticle

Voltage-Gated Sodium Channels
Paralysis
Mutation
Sodium Channels
Point Mutation
95 Citations (Scopus)

Activation and novel processing of matrix metalloproteinases by a thiol-proteinase from the oral anaerobe Porphyromonas gingivalis

DeCarlo, A. A., Windsor, L., Bodden, M. K., Harber, G. J., Birkedal-Hansen, B. & Birkedal-Hansen, H., Jun 1997, In : Journal of Dental Research. 76, 6, p. 1260-1270 11 p.

Research output: Contribution to journalArticle

Porphyromonas gingivalis
Matrix Metalloproteinases
Sulfhydryl Compounds
Peptide Hydrolases
Periodontal Ligament

Activation and proliferation kinetics of single quiescent cd34+ cells residing in GO

Pvatl, R., McMahel, J., Griasbv, S. & Srour, E., 1996, In : Experimental Hematology. 24, 9, p. 1031 1 p.

Research output: Contribution to journalArticle

Clone Cells
Cytokines
Pyronine
Hematopoietic Stem Cells
Bone Marrow Cells
67 Citations (Scopus)

Activation and recovery of the PGE2-mediated sensitization of the capsaicin response in rat sensory neurons

Lopshire, J. C. & Nicol, G., Dec 1997, In : Journal of Neurophysiology. 78, 6, p. 3154-3164 11 p.

Research output: Contribution to journalArticle

Capsaicin
Sensory Receptor Cells
Dinoprostone
Cyclic GMP
Protein Kinases
16 Citations (Scopus)

Activation and routing of membrane-tethered prohormone convertases 1 and 2

Bruzzaniti, A., Marx, R. & Mains, R. E., Aug 27 1999, In : Journal of Biological Chemistry. 274, 35, p. 24703-24713 11 p.

Research output: Contribution to journalArticle

Proprotein Convertase 2
Proprotein Convertase 1
Proprotein Convertases
Pro-Opiomelanocortin
Mixed Function Oxygenases
207 Citations (Scopus)

Activation during ventricular defibrillation in open-chest dogs. Evidence of complete cessation and regeneration of ventricular fibrillation after unsuccessful shocks

Chen, P-S., Shibata, N., Dixon, E. G., Wolf, P. D., Danieley, N. D., Sweeney, M. B., Smith, W. M. & Ideker, R. E., 1986, In : Journal of Clinical Investigation. 77, 3, p. 810-823 14 p.

Research output: Contribution to journalArticle

Ventricular Fibrillation
Regeneration
Shock
Thorax
Dogs
107 Citations (Scopus)

Activation Mechanisms of Conventional Protein Kinase C Isoforms Are Determined by the Ligand Affinity and Conformational Flexibility of Their C1 Domains

Ananthanarayanan, B., Stahelin, R., Digman, M. A. & Cho, W., Nov 21 2003, In : Journal of Biological Chemistry. 278, 47, p. 46886-46894 9 p.

Research output: Contribution to journalArticle

Diglycerides
Protein Kinase C
Protein Isoforms
Chemical activation
Ligands
43 Citations (Scopus)

Activation of 70-kDa S6 kinase, induced by the cytokines interleukin-3 and erythropoietin and inhibited by rapamycin, is not an absolute requirement for cell proliferation

Calvo, V., Wood, M., Gjertson, C., Vik, T. & Bierer, B. E., Nov 1994, In : European Journal of Immunology. 24, 11, p. 2664-2671 8 p.

Research output: Contribution to journalArticle

Ribosomal Protein S6 Kinases
70-kDa Ribosomal Protein S6 Kinases
Interleukin-3
Sirolimus
Erythropoietin
243 Citations (Scopus)

Activation of a caspase 3-related cysteine protease is required for glutamate-mediated apoptosis of cultured cerebellar granule neurons

Du, Y., Bales, K. R., Dodel, R. C., Hamilton-Byrd, E., Horn, J. W., Czilli, D. L., Simmons, L. K., Ni, B. & Paul, S. M., Oct 14 1997, In : Proceedings of the National Academy of Sciences of the United States of America. 94, 21, p. 11657-11662 6 p.

Research output: Contribution to journalArticle

Cysteine Proteases
Caspase 3
Glutamic Acid
Apoptosis
Neurons
1 Citation (Scopus)

Activation of adenylate cyclase from bovine brain caudate nucleus by synthetic analogs of guanyl nucleotides

Skurat, A., Perfilyeva, E. A. & Baranova, L. A., 1982, In : Biokhimiya. 47, 10, p. 1716-1723 8 p.

Research output: Contribution to journalArticle

Guanine Nucleotides
Adenylyl Cyclases
Brain
Animals
Nucleotides
42 Citations (Scopus)

Activation of Akt/FoxO signaling pathway contributes to induction of neuroprotection against transient global cerebral ischemia by hypoxic pre-conditioning in adult rats

Zhan, L., Wang, T., Li, W., Xu, Z. C., Sun, W. & Xu, E., 2010, In : Journal of Neurochemistry. 114, 3, p. 897-908 12 p.

Research output: Contribution to journalArticle

Transient Ischemic Attack
Rats
Ischemia
Chemical activation
Forkhead Transcription Factors
adenosine
smooth muscle
Adenosine
Smooth Muscle
Muscle
474 Citations (Scopus)

Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart

Chen, C. H., Budas, G. R., Churchill, E. N., Disatnik, M. H., Hurley, T. & Mochly-Rosen, D., Sep 12 2008, In : Science. 321, 5895, p. 1493-1495 3 p.

Research output: Contribution to journalArticle

Aldehyde Dehydrogenase
Ischemia
Enzyme Activation
Aldehydes
Proteomics
8 Citations (Scopus)

Activation of AP-1 and increased synthesis of MMP-9 in the rabbit retina induced by lipid hydroperoxide

Iwai, S., Aljada, A., Higa, A., Nakanishi-Ueda, T., Fukuda, S., Kamegawa, M., Iwabuchi, S., Ueda, T., Caballero, S., Browne, R., Afzal, A., Grant, M., Yasuhara, H., Koide, R., Oguchi, K., Dandona, P. & Armstrong, D., May 1 2006, In : Current Eye Research. 31, 4, p. 337-346 10 p.

Research output: Contribution to journalArticle

Lipid Peroxides
Matrix Metalloproteinase 9
Transcription Factor AP-1
Retina
Rabbits
70 Citations (Scopus)

Activation of APE/Ref-1 redox activity is mediated by reactive oxygen species and PKC phosphorylation

Hsieh, M. M., Hegde, V., Kelley, M. & Deutsch, W. A., Jul 15 2001, In : Nucleic Acids Research. 29, 14, p. 3116-3122 7 p.

Research output: Contribution to journalArticle

DNA-(Apurinic or Apyrimidinic Site) Lyase
Oxidation-Reduction
Reactive Oxygen Species
Phosphorylation
DNA
101 Citations (Scopus)

Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP

Pines, A., Perrone, L., Bivi, N., Romanello, M., Damante, G., Gulisano, M., Kelley, M., Quadrifoglio, F. & Tell, G., 2005, In : Nucleic Acids Research. 33, 14, p. 4379-4394 16 p.

Research output: Contribution to journalArticle

Purinergic Receptors
Reactive Oxygen Species
Adenosine Triphosphate
DNA Repair
DNA-(Apurinic or Apyrimidinic Site) Lyase
43 Citations (Scopus)

Activation of arterial matrix metalloproteinases leads to vascular calcification in chronic kidney disease

Chen, X. N., O'Neill, K. D., Chen, X., Kiattisunthorn, K., Gattone, V. H. & Moe, S., Sep 2011, In : American Journal of Nephrology. 34, 3, p. 211-219 9 p.

Research output: Contribution to journalArticle

Vascular Calcification
Matrix Metalloproteinases
Chronic Renal Insufficiency
Matrix Metalloproteinase 2
Matrix Metalloproteinase 9
97 Citations (Scopus)

Activation of a subset of lumbar spinothalamic neurons after copulatory behavior in male but not female rats

Truitt, W., Shipley, M. T., Veening, J. G. & Coolen, L. M., Jan 1 2003, In : Journal of Neuroscience. 23, 1, p. 325-331 7 p.

Research output: Contribution to journalArticle

Ejaculation
Neurons
Galanin
Copulation
Spinal Cord

Activation of BNIP3-mediated mitophagy protects against renal ischemia-reperfusion injury

Tang, C., Han, H., Liu, Z., Liu, Y., Yin, L., Cai, J., He, L., Liu, Y., Chen, G., Zhang, Z., Yin, X-M. & Dong, Z., Sep 12 2019, In : Cell death & disease. 10, 9, 1 p.

Research output: Contribution to journalArticle

Open Access
Proto-Oncogene Proteins c-bcl-2
Mitochondrial Degradation
Reperfusion Injury
Kidney
Acute Kidney Injury