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47 Citations (Scopus)

Activation of branched-chain α-keto acid dehydrogenase complex by exercise: Effect of high-fat diet intake

Shimomura, Y., Suzuki, T., Saitoh, S., Tasaki, Y., Harris, R. & Suzuki, M., 1990, In : Journal of Applied Physiology. 68, 1, p. 161-165 5 p.

Research output: Contribution to journalArticle

3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)
High Fat Diet
Diet
Liver
Muscles
12 Citations (Scopus)

Activation of branched-chain α-ketoacid dehydrogenase in isolated hepatocytes by branched-chain α-ketoacids

Han, A. C., Goodwin, G. W., Paxton, R. & Harris, R., 1987, In : Archives of Biochemistry and Biophysics. 258, 1, p. 85-94 10 p.

Research output: Contribution to journalArticle

3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)
Rats
Hepatocytes
Chemical activation
Decarboxylation
47 Citations (Scopus)

Activation of calcium-independent phospholipase a2 (iPLA 2) in brain mitochondria and release of apoptogenic factors by BAX and truncated BID

Brustovetsky, T., Antonsson, B., Jemmerson, R., Dubinsky, J. M. & Broustovetski, N., Aug 2005, In : Journal of Neurochemistry. 94, 4, p. 980-994 15 p.

Research output: Contribution to journalArticle

Calcium-Independent Phospholipase A2
Mitochondria
Cytochromes c
Phospholipases A2
Brain
3 Citations (Scopus)

Activation of cAMP-responsive-element-binding protein by PI3 kinase and p38 MAPK is essential for elevated expression of transforming growth factor β2 in cancer cells

Wan, Y., Yang, M., Kolattukudy, S., Stark, G. R. & Lu, T., Sep 1 2010, In : Journal of Interferon and Cytokine Research. 30, 9, p. 677-681 5 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
p38 Mitogen-Activated Protein Kinases
Phosphatidylinositol 3-Kinases
Cyclic AMP
Protein Kinases
16 Citations (Scopus)

Activation of carbohydrate response element-binding protein by ethanol

Liangpunsakul, S., Ross, R. A. & Crabb, D., Feb 2013, In : Journal of Investigative Medicine. 61, 2, p. 270-277 8 p.

Research output: Contribution to journalArticle

Response Elements
Carrier Proteins
Ethanol
Chemical activation
Carbohydrates
31 Citations (Scopus)

Activation of complement by fluosol attributable to the pluronic detergent micelle structure

Ingram, D., Forman, M. B. & Murray, J. J., 1993, In : Journal of Cardiovascular Pharmacology. 22, 3, p. 456-461 6 p.

Research output: Contribution to journalArticle

Poloxamer
Complement Activation
Fluorocarbons
Micelles
Detergents
25 Citations (Scopus)

Activation of CpxRA in Haemophilus ducreyi primarily inhibits the expression of Its targets, including major virulence determinants

Gangaiah, D., Zhang, X., Fortney, K. R., Baker, B., Liu, Y., Munson, R. S. & Spinola, S., Aug 2013, In : Journal of Bacteriology. 195, 15, p. 3486-3502 17 p.

Research output: Contribution to journalArticle

Haemophilus ducreyi
Virulence
Phosphoric Monoester Hydrolases
Operon
Down-Regulation
2 Citations (Scopus)

Activation of death-associated protein kinase in human peritumoral tissue: A potential therapeutic target

Gao, X., Wang, H., Pollok, K., Chen, J. & Cohen-Gadol, A., Oct 1 2015, In : Journal of Clinical Neuroscience. 22, 10, p. 1655-1660 6 p., 6063.

Research output: Contribution to journalArticle

Death-Associated Protein Kinases
Glioma
Therapeutics
Seizures
Glutamate Receptors
10 Citations (Scopus)

Activation of dendritic cell function by soypeptide lunasin as a novel vaccine adjuvant

Tung, C. Y., Lewis, D. E., Han, L., Jaja, M., Yao, S., Li, F., Robertson, M., Zhou, B., Sun, J. & Chang, H. C., 2014, In : Vaccine. 32, 42, p. 5411-5419 9 p.

Research output: Contribution to journalArticle

vaccine adjuvants
ovalbumin
Ovalbumin
dendritic cells
Dendritic Cells
123 Citations (Scopus)

Activation of dendritic cells and induction of CD4+ T cell differentiation by aluminum-containing adjuvants

Sokolovska, A., Hem, S. L. & HogenEsch, H., Jun 6 2007, In : Vaccine. 25, 23, p. 4575-4585 11 p.

Research output: Contribution to journalArticle

dendritic cells
Aluminum
cell differentiation
Dendritic Cells
adjuvants
62 Citations (Scopus)

Activation of endothelial cell phospholipase D by sphingosine and sphingosine-1-phosphate.

Natarajan, V., Jayaram, H. N., Scribner, W. M. & Garcia, J. G., Aug 1994, In : American Journal of Respiratory Cell and Molecular Biology. 11, 2, p. 221-229 9 p.

Research output: Contribution to journalArticle

Phospholipase D
Sphingosine
Endothelial cells
Endothelial Cells
Chemical activation
234 Citations (Scopus)

Activation of epidermal vanilloid receptor-1 induces release of proinflammatory mediators in human keratinocytes

Southall, M. D., Li, T., Gharibova, L. S., Pei, Y., Nicol, G. & Travers, J., Jan 1 2003, In : Journal of Pharmacology and Experimental Therapeutics. 304, 1, p. 217-222 6 p.

Research output: Contribution to journalArticle

Keratinocytes
Capsaicin
Cyclooxygenase 2
Skin
vanilloid receptor subtype 1
7 Citations (Scopus)

Activation of Hedgehog Pathway in Gastrointestinal Cancers

Yang, L., Su, X. & Xie, J., 2012, In : Vitamins and Hormones. 88, p. 461-472 12 p.

Research output: Contribution to journalArticle

Gastrointestinal Neoplasms
Neoplasms
Medulloblastoma
Basal Cell Carcinoma
Ovarian Neoplasms
24 Citations (Scopus)

Activation of hedgehog signaling is not a frequent event in ovarian cancers

Yang, L., He, J., Huang, S., Zhang, X., Bian, Y., He, N., Zhang, H. & Xie, J., Nov 27 2009, In : Molecular Cancer. 8, 112.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Neoplasms
Gene Expression
Phase II Clinical Trials
In Situ Hybridization
48 Citations (Scopus)

Activation of human D3 dopamine receptor inhibits P/Q-type calcium channels and secretory activity in AtT-20 cells

Kuzhikandathil, E. V. & Oxford, G. S., Mar 1 1999, In : Journal of Neuroscience. 19, 5, p. 1698-1707 10 p.

Research output: Contribution to journalArticle

Q-Type Calcium Channels
P-Type Calcium Channels
Dopamine D3 Receptors
Neurotransmitter Agents
Ligands
152 Citations (Scopus)

Activation of human neutrophils induces an interaction between the Lntegrin β2-subunit (CD18) and the actin binding protein α-actinin

Pavalko, F. & LaRoche, S. M., Oct 1 1993, In : Journal of Immunology. 151, 7, p. 3795-3807 13 p.

Research output: Contribution to journalArticle

Actinin
Microfilament Proteins
Neutrophil Activation
Integrins
Lymphocyte Function-Associated Antigen-1
40 Citations (Scopus)

Activation of human progelatinase A by collagenase and matrilysin: Activation of procollagenase by matrilysin

Sang, Q. A., Bodden, M. K. & Windsor, L. J., 1996, In : Protein Journal. 15, 3, p. 243-253 11 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 7
Collagenases
Fibroblasts
Chemical activation
Matrix Metalloproteinase 2
32 Citations (Scopus)

Activation of individual tumor necrosis factor receptors differentially affects stem cell growth factor and cytokine production

Markel, T. A., Crisostomo, P. R., Wang, M., Herring, C. M. & Meldrum, D. R., Oct 2007, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 293, 4

Research output: Contribution to journalArticle

Stem Cell Factor
Tumor Necrosis Factor Receptors
Intercellular Signaling Peptides and Proteins
Vascular Endothelial Growth Factor A
Cytokines
12 Citations (Scopus)

Activation of latent transforming growth factor beta during chlamydia trachomatis -induced murine pneumonia

Williams, D. M., Grubbs, B. G., Park-Snyder, S., Rank, R. G. & Bonewald, L., 1996, In : Research in Microbiology. 147, 4, p. 251-262 12 p.

Research output: Contribution to journalArticle

Chlamydia trachomatis
Transforming Growth Factor beta
Pneumonia
Polymerase Chain Reaction
Reverse Transcription
93 Citations (Scopus)

Activation of MAP kinase in vivo follows balloon overstretch injury of porcine coronary and carotid arteries

Pyles, J. M., March, K. L., Franklin, M., Mehdi, K., Wilensky, R. L. & Adam, L. P., 1997, In : Circulation Research. 81, 6, p. 904-910 7 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinases
Carotid Arteries
Coronary Vessels
Phosphotransferases
Swine
29 Citations (Scopus)

Activation of maternal mRNA in the absence of poly(A) formation in fertilised sea urchin eggs

Mescher, A. & Humphreys, T., 1974, In : Nature. 249, 5453, p. 138-139 2 p.

Research output: Contribution to journalArticle

Stored Messenger RNA
Poly A
Sea Urchins
Fertilization
Eggs
25 Citations (Scopus)

Activation of mTOR pathway in myeloid-derived suppressor cells stimulates cancer cell proliferation and metastasis in lal<sup>-/-</sup> mice

Zhao, T., Du, H., Ding, X., Walls, K. & Yan, C., May 26 2014, In : Oncogene. 34, 15, p. 1938-1948 11 p.

Research output: Contribution to journalArticle

Sirolimus
Cell Proliferation
Neoplasm Metastasis
Neoplasms
Experimental Melanomas
25 Citations (Scopus)

Activation of NF-κB by fluid shear stress, but not TNF-α, requires focal adhesion kinase in osteoblasts

Young, S. R. L., Gerard-O'Riley, R., Harrington, M. & Pavalko, F., Jul 2010, In : Bone. 47, 1, p. 74-82 9 p.

Research output: Contribution to journalArticle

Focal Adhesion Protein-Tyrosine Kinases
NF-kappa B
Osteoblasts
Tumor Necrosis Factor-alpha
Bone and Bones
23 Citations (Scopus)

Activation of OCT4 enhances ex vivo expansion of human cord blood hematopoietic stem and progenitor cells by regulating HOXB4 expression

Huang, X., Lee, M. R., Cooper, S., Hangoc, G., Hong, K. S., Chung, H. M. & Broxmeyer, H., Jan 1 2016, In : Leukemia. 30, 1, p. 144-153 10 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Fetal Blood
Adult Stem Cells
Small Interfering RNA
Blood Cells
25 Citations (Scopus)

Activation of platelet-activating factor receptor in SZ95 sebocytes results in inflammatory cytokine and prostaglandin E2 production

Zhang, Q., Seltmann, H., Zouboulis, C. C. & Travers, J., Oct 2006, In : Experimental Dermatology. 15, 10, p. 769-774 6 p.

Research output: Contribution to journalArticle

Platelet Activating Factor
Dinoprostone
Chemical activation
Cytokines
Cyclooxygenase 2
37 Citations (Scopus)

Activation of poly(ADP-ribose) polymerase in severe hemorrhagic shock and resuscitation

Watts, J. A., Grattan, R. M., Whitlow, B. S. & Kline, J., 2001, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 281, 2 44-2

Research output: Contribution to journalArticle

Poly(ADP-ribose) Polymerases
Hemorrhagic Shock
Resuscitation
Ileum
Acidosis
3 Citations (Scopus)

Activation of porcine hepatic microvascular sinusoidal endothelial cells in pig-to-human liver xenotransplantation

Di Carlo, A., Tector, A. J., Liu, S., Tan, M., Barkun, J. S., Soderland, C., Metrakos, P. & Tchervenkov, J. I., 2001, In : Transplantation Proceedings. 33, 1-2, p. 759-761 3 p.

Research output: Contribution to journalArticle

Heterologous Transplantation
Vascular Endothelium
Endothelin-1
Microcirculation
Interleukin-1

Activation of primary human chronic lymphocytic leukemia (cll) cells by interleukin-2 (il-2): implications for cancer vaccine development

Robertson, M., Ganjoo, K. & Timmons, L., 2000, In : Blood. 96, 11 PART II

Research output: Contribution to journalArticle

Cancer Vaccines
B-Cell Chronic Lymphocytic Leukemia
Interleukin-2
Chemical activation
Cell culture
111 Citations (Scopus)

Activation of Pro-death Bcl-2 Family Proteins and Mitochondria Apoptosis Pathway in Tumor Necrosis Factor-α-induced Liver Injury

Zhao, Y., Li, S., Childs, E. E., Kuharsky, D. K. & Yin, X-M., Jul 20 2001, In : Journal of Biological Chemistry. 276, 29, p. 27432-27440 9 p.

Research output: Contribution to journalArticle

Mitochondria
Liver
Tumor Necrosis Factor-alpha
Chemical activation
Apoptosis
83 Citations (Scopus)

Activation of protein kinase C augments peptide release from rat sensory neurons

Barber, L. A. & Vasko, M., Jul 1996, In : Journal of Neurochemistry. 67, 1, p. 72-80 9 p.

Research output: Contribution to journalArticle

Sensory Receptor Cells
Protein Kinase C
Neurons
Rats
Phorbol 12,13-Dibutyrate
17 Citations (Scopus)

Activation of protein kinase C enhances peptide release from rat spinal cord slices

Frayer, S. M., Barber, L. A. & Vasko, M., Apr 9 1999, In : Neuroscience Letters. 265, 1, p. 17-20 4 p.

Research output: Contribution to journalArticle

Phorbol 12,13-Dibutyrate
Protein Kinase C
Spinal Cord
Peptides
Capsaicin
4 Citations (Scopus)

Activation of PTHrP gene expression in squamous carcinoma cell lines by mutant isoforms of the tumor suppressor p53

Foley, J., King, C. S., Jiménez, J. A., Wysolmerski, J. J. & Philbrick, W. M., 2000, In : Oncology Research. 12, 2, p. 71-81 11 p.

Research output: Contribution to journalArticle

Parathyroid Hormone-Related Protein
Squamous Cell Carcinoma
Protein Isoforms
Gene Expression
Cell Line
25 Citations (Scopus)

Activation of pyruvate dehydrogenase improves heart function and metabolism after hemorrhagic shock

Kline, J., Maiorano, P. C., Schroeder, J. D., Grattan, R. M., Vary, T. C. & Watts, J. A., Sep 1997, In : Journal of Molecular and Cellular Cardiology. 29, 9, p. 2465-2474 10 p.

Research output: Contribution to journalArticle

Hemorrhagic Shock
Pyruvic Acid
Oxidoreductases
Weights and Measures
Phosphocreatine
10 Citations (Scopus)

Activation of Rap1 inhibits NADPH oxidase-dependent ROS generation in retinal pigment epithelium and reduces choroidal neovascularization

Wang, H., Jiang, Y., Shi, D., Quilliam, L., Chrzanowska-Wodnicka, M., Wittchen, E. S., Li, D. Y. & Hartnett, M. E., 2014, In : FASEB Journal. 28, 1, p. 265-274 10 p.

Research output: Contribution to journalArticle

Choroidal Neovascularization
Retinal Pigments
Retinal Pigment Epithelium
NADPH Oxidase
Pigments
157 Citations (Scopus)

Activation of Rho-associated coiled-coil protein kinase 1 (ROCK-1) by caspase-3 cleavage plays an essential role in cardiac myocyte apoptosis

Chang, J., Xie, M., Shah, V. R., Schneider, M. D., Entman, M. L., Wei, L. & Schwartz, R. J., Sep 26 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 39, p. 14495-14500 6 p.

Research output: Contribution to journalArticle

rho-Associated Kinases
Cardiac Myocytes
Caspase 3
Protein Kinases
Apoptosis
36 Citations (Scopus)

Activation of serotonin-3 receptors increases dopamine release within the ventral tegmental area of Wistar and alcohol-preferring (P) rats

Liu, W., Thielen, R. J., Rodd, Z. & McBride, W. J., Nov 2006, In : Alcohol. 40, 3, p. 167-176 10 p.

Research output: Contribution to journalArticle

Receptors, Serotonin, 5-HT3
Ventral Tegmental Area
activation
Rats
Dopamine
67 Citations (Scopus)

Activation of Src by protein tyrosine phosphatase 1B is required for ErbB2 transformation of human breast epithelial cells

Arias-Romero, L. E., Saha, S., Villamar-Cruz, O., Yip, S. C., Ethier, S. P., Zhang, Z-Y. & Chernoff, J., Jun 1 2009, In : Cancer Research. 69, 11, p. 4582-4588 7 p.

Research output: Contribution to journalArticle

Non-Receptor Type 1 Protein Tyrosine Phosphatase
Non-Receptor Type 2 Protein Tyrosine Phosphatase
Breast
Epithelial Cells
Leptin Receptors
251 Citations (Scopus)

Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism

Su, W. C. S., Kitagawa, M., Xue, N., Xie, B., Garofalo, S., Cho, J., Deng, C., Horton, W. A. & Fu, X. Y., Mar 20 1997, In : Nature. 386, 6622, p. 288-292 5 p.

Research output: Contribution to journalArticle

Thanatophoric Dysplasia
Dwarfism
Fibroblast Growth Factor Receptors
Achondroplasia
Fetus
2 Citations (Scopus)

Activation of T-cells through an antigen-independent alternative pathway induces precocious sensitivity to Fas-induced apoptosis

Bonay, M., Bouchonnet, F., Lecossier, D., Boumsell, L., Soler, P., Grodet, A., Robertson, M. & Hance, A. J., Nov 1997, In : Immunology Letters. 59, 2, p. 107-113 7 p.

Research output: Contribution to journalArticle

CD27 Antigens
Apoptosis
Ionophores
T-Lymphocytes
Interleukin-2
46 Citations (Scopus)

Activation of the ACE2/angiotensin-(1-7)/mas receptor axis enhances the reparative function of dysfunctional diabetic endothelial progenitors

Jarajapu, Y. P. R., Bhatwadekar, A., Caballero, S., Hazra, S., Shenoy, V., Medina, R., Kent, D., Stitt, A. W., Thut, C., Finney, E. M., Raizada, M. K. & Grant, M. B., Apr 2013, In : Diabetes. 62, 4, p. 1258-1269 12 p.

Research output: Contribution to journalArticle

Enzyme Activators
Phosphatidylinositol 3-Kinase
NADPH Oxidase
Renin-Angiotensin System
Stromal Cells
83 Citations (Scopus)

Activation of the Arp2/3 complex by N-WASp is required for actin polymerization and contraction in smooth muscle

Zhang, W., Wu, Y., Du, L., Tang, D. D. & Gunst, S., May 2005, In : American Journal of Physiology - Cell Physiology. 288, 5 57-5

Research output: Contribution to journalArticle

Neuronal Wiskott-Aldrich Syndrome Protein
Actin-Related Protein 2-3 Complex
Polymerization
Smooth Muscle
Muscle
218 Citations (Scopus)

Activation of the bone-derived latent TGF beta complex by isolated osteoclasts

Oreffo, R. O. C., Mundy, G. R., Seyedin, S. M. & Bonewald, L., Feb 15 1989, In : Biochemical and Biophysical Research Communications. 158, 3, p. 817-823 7 p.

Research output: Contribution to journalArticle

Osteoclasts
Transforming Growth Factor beta
Bone
Chemical activation
Bone and Bones
33 Citations (Scopus)

Activation of the branched-chain α-ketoacid dehydrogenase complex by a broad specificity protein phosphatase

Harris, R., Paxton, R. & Parker, R. A., Aug 31 1982, In : Biochemical and Biophysical Research Communications. 107, 4, p. 1497-1503 7 p.

Research output: Contribution to journalArticle

3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)
Phosphoprotein Phosphatases
Rats
Chemical activation
Tissue Extracts
38 Citations (Scopus)

Activation of the CpxRA system by deletion of cpxA impairs the ability of Haemophilus ducreyi to infect humans

Spinola, S., Fortney, K. R., Baker, B., Janowicz, D., Zwickl, B., Katz, B., Blick, R. J. & Munson, R. S., Sep 2010, In : Infection and Immunity. 78, 9, p. 3898-3904 7 p.

Research output: Contribution to journalArticle

Haemophilus ducreyi
Phosphoric Monoester Hydrolases
Down-Regulation
Periplasm
Operon
93 Citations (Scopus)

Activation of the epidermal platelet-activating factor receptor results in cytokine and cyclooxygenase-2 biosynthesis

Pei, Y., Barber, L. A., Murphy, R. C., Johnson, C. A., Kelley, S. W., Dy, L. C., Fertel, R. H., Nguyen, T. M., Williams, D. A. & Travers, J., Aug 15 1998, In : Journal of Immunology. 161, 4, p. 1954-1961 8 p.

Research output: Contribution to journalArticle

Platelet Activating Factor
Cyclooxygenase 2
Cytokines
Keratinocytes
Interleukin-8
2 Citations (Scopus)

Activation of the epidermal platelet-activating factor receptor results in ICAM-1 expression [4]

Pei, Y., Dy, L. C., Natarajan, S. & Travers, J., 2000, In : In Vitro Cellular and Developmental Biology - Animal. 36, 1, p. 11-13 3 p.

Research output: Contribution to journalArticle

233 Citations (Scopus)

Activation of the hedgehog pathway in advanced prostate cancer

Sheng, T., Li, C., Zhang, X., Chi, S., He, N., Chen, K., McCormick, F., Gatalica, Z. & Xie, J., Oct 13 2004, In : Molecular Cancer. 3, 29.

Research output: Contribution to journalArticle

Tumors
Prostatic Neoplasms
Chemical activation
Hedgehog Proteins
Neoplasms
49 Citations (Scopus)

Activation of the hedgehog pathway in a subset of lung cancers

Chi, S., Huang, S., Li, C., Zhang, X., He, N., Bhutani, M. S., Jones, D., Castro, C. Y., Logrono, R., Haque, A., Zwischenberger, J., Tyring, S. K., Zhang, H. & Xie, J., Nov 28 2006, In : Cancer Letters. 244, 1, p. 53-60 8 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Gene Expression
In Situ Hybridization
Neoplasms
Down-Regulation
173 Citations (Scopus)

Activation of the hedgehog pathway in human hepatocellular carcinomas

Huang, S., He, J., Zhang, X., Bian, Y., Yang, L., Xie, G., Zhang, K., Tang, W., Stelter, A. A., Wang, Q., Zhang, H. & Xie, J., Jul 2006, In : Carcinogenesis. 27, 7, p. 1334-1340 7 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Neoplasms
Genes
Cell Line
Gastrointestinal Neoplasms
206 Citations (Scopus)

Activation of the hedgehog-signaling pathway in human cancer and the clinical implications

Yang, L., Xie, G., Fan, Q. & Xie, J., Jan 2010, In : Oncogene. 29, 4, p. 469-481 13 p.

Research output: Contribution to journalArticle

Hedgehogs
Neoplasms
Medulloblastoma
Gastrointestinal Neoplasms
Basal Cell Carcinoma