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87 Citations (Scopus)

Activation of the insulin-like growth factor-1 receptor promotes the survival of human keratinocytes following ultraviolet B irradiation

Kuhn, C., Hurwitz, S. A., Kumar, M. G., Cotton, J. & Spandau, D., 1999, In : International Journal of Cancer. 80, 3, p. 431-438 8 p.

Research output: Contribution to journalArticle

Somatomedin Receptors
IGF Type 1 Receptor
Keratinocytes
Apoptosis
DNA Damage
158 Citations (Scopus)

Activation of the Janus kinase/STAT (signal transducer and activator of transcription) signal transduction pathway by interleukin-6-type cytokines promotes osteoblast differentiation

Bellido, T., Borba, V. Z. C., Roberson, P. & Manolagas, S. C., 1997, In : Endocrinology. 138, 9, p. 3666-3676 11 p.

Research output: Contribution to journalArticle

Janus Kinases
Transducers
Osteoblasts
Interleukin-6
Signal Transduction
136 Citations (Scopus)

Activation of the JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis

Atzori, C., Ghetti, B., Piva, R., Srinivasan, A. N., Zolo, P., Delisle, M. B., Mirra, S. S. & Migheli, A., 2001, In : Journal of Neuropathology and Experimental Neurology. 60, 12, p. 1190-1197 8 p.

Research output: Contribution to journalArticle

tau Proteins
MAP Kinase Signaling System
Phosphotransferases
Phosphorylation
Apoptosis
56 Citations (Scopus)

Activation of the left planum temporale in pitch processing is shaped by language experience

Xu, Y., Gandour, J., Talavage, T., Wong, D., Dzemidzic, M., Tong, Y., Li, X. & Lowe, M., Feb 2006, In : Human Brain Mapping. 27, 2, p. 173-183 11 p.

Research output: Contribution to journalArticle

Temazepam
Language
Linguistics
Automatic Data Processing
Population Groups
18 Citations (Scopus)

Activation of the midbrain periaqueductal gray induces airway smooth muscle relaxation

Haxhiu, M. A., Yamamoto, B., Dreshaj, I. A. & Ferguson, D. G., 2002, In : Journal of Applied Physiology. 93, 2, p. 440-449 10 p.

Research output: Contribution to journalArticle

Periaqueductal Gray
Muscle Relaxation
Medulla Oblongata
GABA-A Receptors
Mesencephalon
61 Citations (Scopus)

Activation of the mitogen-activated protein kinase pathway is involved in and sufficient for megakaryocytic differentiation of CMK cells

Melemed, A. S., Ryder, J. W. & Vik, T., 1997, In : Blood. 90, 9, p. 3462-3470 9 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinases
Cell Differentiation
Chemical activation
Phosphotransferases
Mitogen-Activated Protein Kinase Kinases
34 Citations (Scopus)

Activation of the neutrophil respiratory burst requires both intracellular and extracellular calcium

Kim-Park, W. K., Moore, M. A., Hakki, Z. W. & Kowolik, M., Dec 15 1997, In : Annals of the New York Academy of Sciences. 832, p. 394-404 11 p.

Research output: Contribution to journalArticle

Neutrophil Activation
Respiratory Burst
Phosphoric Monoester Hydrolases
Vanadates
Chemiluminescence
55 Citations (Scopus)

Activation of the orexin 1 receptor is a critical component of CO 2-mediated anxiety and hypertension but not bradycardia

Johnson, P., Samuels, B. C., Fitz, S. D., Lightman, S. L., Lowry, C. A. & Shekhar, A., Jul 2012, In : Neuropsychopharmacology. 37, 8, p. 1911-1922 12 p.

Research output: Contribution to journalArticle

Orexin Receptors
Carbon Monoxide
Bradycardia
Anxiety
Hypercapnia
12 Citations (Scopus)

Activation of the prolactin promoter in transfected GH3 cells by posterior pituitary cells

Steinmetz, R., Gutierrez-Hartmann, A., Bigsby, R. & Ben-Jonathan, N., Dec 1994, In : Endocrinology. 135, 6, p. 2737-2741 5 p.

Research output: Contribution to journalArticle

Prolactin
Vasoactive Intestinal Peptide
Luciferases
Epidermal Growth Factor
PC12 Cells
14 Citations (Scopus)

Activation of the Ras superfamily of small GTPases. Workshop on exchange factors

Zheng, Y. & Quilliam, L., May 1 2003, In : EMBO Reports. 4, 5, p. 463-468 6 p.

Research output: Contribution to journalArticle

rap GTP-Binding Proteins
Receptor Cross-Talk
Guanine Nucleotide Exchange Factors
ras Proteins
Biological Models
102 Citations (Scopus)
Alveolar Epithelial Cells
STAT3 Transcription Factor
Adenocarcinoma
Inflammation
Chemokines
15 Citations (Scopus)

Activation of the Smooth Muscle-specific Telokin Gene by Thyrotroph Embryonic Factor (TEF)

Zhou, J., Hoggatt, A. M. & Herring, B., Apr 16 2004, In : Journal of Biological Chemistry. 279, 16, p. 15929-15937 9 p.

Research output: Contribution to journalArticle

Thyrotrophs
Smooth Muscle
Muscle
Genes
Chemical activation
428 Citations (Scopus)

Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis

Chin, Y. E., Kitagawa, M., Kuida, K., Flavell, R. A. & Fu, X. Y., Sep 1997, In : Molecular and Cellular Biology. 17, 9, p. 5328-5337 10 p.

Research output: Contribution to journalArticle

Caspase 1
Transducers
Apoptosis
Interferons
Epidermal Growth Factor
99 Citations (Scopus)

Activation of the wnt pathway plays a pathogenic role in diabetic retinopathy in humans and animal models

Chen, Y., Hu, Y., Zhou, T., Zhou, K. K., Mott, R., Wu, M., Boulton, M., Lyons, T. J., Gao, G. & Ma, J. X., 2009, In : American Journal of Pathology. 175, 6, p. 2676-2685 10 p.

Research output: Contribution to journalArticle

Wnt Signaling Pathway
Diabetic Retinopathy
Animal Models
Catenins
Low Density Lipoprotein Receptor-Related Protein-6
17 Citations (Scopus)

Activation of the β-catenin signaling pathway and its impact on RPE cell cycle

Steindl-Kuscher, K., Krugluger, W., Boulton, M. E., Haas, P., Schrattbauer, K., Feichtinger, H., Adlassnig, W. & Binder, S., 2009, In : Investigative Ophthalmology and Visual Science. 50, 9, p. 4471-4476 6 p.

Research output: Contribution to journalArticle

Catenins
Cell Cycle
Insulin-Like Growth Factor I
Epidermal Growth Factor
Glycogen Synthase Kinase 3
75 Citations (Scopus)

Activation of transcription by PU.1 requires both acidic and glutamine domains

Klemsz, M. & Maki, R. A., Jan 1996, In : Molecular and Cellular Biology. 16, 1, p. 390-397 8 p.

Research output: Contribution to journalArticle

Activation Analysis
Glutamine
Transcriptional Activation
Amino Acids
Aptitude
81 Citations (Scopus)

Activation of transcription factors activator protein-1 and nuclear factor-κB by 2,3,7,8-Tetrachlorodibenzo-p-dioxin

Puga, A., Barnes, S. J., Chang, C. Y., Zhu, H., Nephew, K., Khan, S. A. & Shertzer, H. G., Apr 15 2000, In : Biochemical Pharmacology. 59, 8, p. 997-1005 9 p.

Research output: Contribution to journalArticle

Transcription Factor AP-1
Aromatic Hydrocarbons
Transcription Factors
Chemical activation
Cytochrome P-450 Enzyme System
112 Citations (Scopus)

Activation of Vascular Endothelial Growth Factor Receptor-1 Sustains Angiogenesis and Bcl-2 Expression Via the Phosphatidylinositol 3-Kinase Pathway in Endothelial Cells

Cai, J., Ahmad, S., Jiang, W. G., Huang, J., Kontos, C. D., Boulton, M. & Ahmed, A., Dec 2003, In : Diabetes. 52, 12, p. 2959-2968 10 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Vascular Endothelial Growth Factor Receptor-1
Endothelial Cells
Vascular Endothelial Growth Factor A
Pathologic Neovascularization
51 Citations (Scopus)

Activation of vascular smooth muscle cells by TNF and PDGF: Overlapping and complementary signal transduction mechanisms

Peppel, K., Zhang, L., Orman, E., Hagen, P. O., Amalfitano, A., Brian, L. & Freedman, N. J., Feb 15 2005, In : Cardiovascular Research. 65, 3, p. 674-682 9 p.

Research output: Contribution to journalArticle

Platelet-Derived Growth Factor
Vascular Smooth Muscle
Smooth Muscle Myocytes
Signal Transduction
Tumor Necrosis Factor-alpha
40 Citations (Scopus)

Activation of vinculin induced by cholinergic stimulation regulates contraction of tracheal smooth muscle tissue

Huang, Y., Zhang, W. & Gunst, S., Feb 4 2011, In : Journal of Biological Chemistry. 286, 5, p. 3630-3644 15 p.

Research output: Contribution to journalArticle

Vinculin
Cholinergic Agents
Smooth Muscle
Muscle
Chemical activation
31 Citations (Scopus)
Wiskott-Aldrich Syndrome Protein
Chemokine CXCL12
Crk-Associated Substrate Protein
Cell Movement
T-Lymphocytes
1 Citation (Scopus)

Activation State-Dependent Substrate Gating in Ca2+/Calmodulin-Dependent Protein Kinase II

Johnson, D. E. & Hudmon, A., Jan 1 2017, In : Neural Plasticity. 2017, 9601046.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Type 2
Holoenzymes
Catalytic Domain
Calcium-Calmodulin-Dependent Protein Kinases
Protein Isoforms
18 Citations (Scopus)

Activator protein-1 has an essential role in pancreatic cancer cells and is regulated by a novel Akt-mediated mechanism

Shin, S., Asano, T., Yao, Y., Zhang, R., Claret, F. X., Korc, M., Sabapathy, K., Menter, D. G., Abbruzzese, J. L. & Reddy, S. A. G., May 2009, In : Molecular Cancer Research. 7, 5, p. 745-754 10 p.

Research output: Contribution to journalArticle

Transcription Factor AP-1
Pancreatic Neoplasms
Glycogen Synthase Kinase 3
JNK Mitogen-Activated Protein Kinases
Cyclin D1
111 Citations (Scopus)

Activators of protein kinase C decrease Ca2+ spark frequency in smooth muscle cells from cerebral arteries

Bonev, A. D., Jaggar, J. H., Rubart-von der Lohe, M. & Nelson, M. T., 1997, In : American Journal of Physiology - Cell Physiology. 273, 6 42-6

Research output: Contribution to journalArticle

Cerebral Arteries
Electric sparks
Protein Kinase C
Smooth Muscle Myocytes
Muscle
5 Citations (Scopus)

Active ageing and success: A brief history of conceptual models

Petretto, D. R., Pili, R., Gaviano, L., Matos López, C. & Zuddas, C., Nov 28 2014, (Accepted/In press) In : Revista Espanola de Geriatria y Gerontologia.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Active and passive arteriolar regulation in spontaneously hypertensive rats

Bohlen, H. & Lash, J. M., Jun 1994, In : Hypertension. 23, 6 I, p. 757-764 8 p.

Research output: Contribution to journalArticle

Inbred SHR Rats
Arterioles
Inbred WKY Rats
Cyclic GMP
Nitroprusside
103 Citations (Scopus)

Active and passive P3 latency and psychometric performance: influence of age and individual differences

O'Donnell, B., Friedman, S., Swearer, J. M. & Drachman, D. A., 1992, In : International Journal of Psychophysiology. 12, 2, p. 187-195 9 p.

Research output: Contribution to journalArticle

Psychometrics
Individuality
Verbal Learning
Intelligence
P300 Event-Related Potentials
49 Citations (Scopus)

Active and passive P3 latency in dementia: Relationship to psychometric, electroencephalographic, and computed tomographic measures

O'Donnell, B., Friedman, S., Squires, N. K., Maloon, A., Drachman, D. A. & Swearer, J. M., 1990, In : Neuropsychiatry, Neuropsychology and Behavioral Neurology. 3, 3, p. 164-179 16 p.

Research output: Contribution to journalArticle

Psychometrics
Dementia
Wechsler Scales
Intelligence
Reaction Time
24 Citations (Scopus)

Active Aβ immunotherapy CAD106 in Alzheimer's disease: A phase 2b study

Vandenberghe, R., Riviere, M. E., Caputo, A., Sovago, J., Maguire, R. P., Farlow, M., Marotta, G., Sanchez-Valle, R., Scheltens, P., Ryan, J. M. & Graf, A., Jan 1 2017, In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 3, 1, p. 10-22 13 p.

Research output: Contribution to journalArticle

Active Immunotherapy
Amyloid
Alzheimer Disease
Positron-Emission Tomography
Placebos
33 Citations (Scopus)

ACTIVE cognitive training and rates of incident dementia

Unverzagt, F., Guey, L. T., Jones, R. N., Marsiske, M., King, J. W., Wadley, V. G., Crowe, M., Rebok, G. W. & Tennstedt, S. L., Jul 2012, In : Journal of the International Neuropsychological Society. 18, 4, p. 669-677 9 p.

Research output: Contribution to journalArticle

dementia
Dementia
incident
Survival Analysis
Activities of Daily Living
39 Citations (Scopus)

Active idiotypic vaccination versus control immunotherapy for follicular lymphoma

Levy, R., Ganjoo, K. N., Leonard, J. P., Vose, J. M., Flinn, I. W., Ambinder, R. F., Connors, J. M., Berinstein, N. L., Belch, A. R., Bartlett, N. L., Nichols, C., Emmanouilides, C. E., Timmerman, J. M., Gregory, S. A., Link, B. K., Inwards, D. J., Freedman, A. S., Matous, J. V., Robertson, M., Kunkel, L. A. & 6 others, Ingolia, D. E., Gentles, A. J., Liu, C. L., Tibshirani, R., Alizadeh, A. A. & Denney, D. W., Jun 10 2014, In : Journal of Clinical Oncology. 32, 17, p. 1797-1803 7 p.

Research output: Contribution to journalArticle

Follicular Lymphoma
Immunotherapy
Vaccination
Disease-Free Survival
Granulocyte-Macrophage Colony-Stimulating Factor
5 Citations (Scopus)
Problem-Based Learning
Nursing Students
Evidence-Based Practice
Nursing
Guidelines
8 Citations (Scopus)

Active PSF shaping and adaptive optics enable volumetric localization microscopy through brain sections

Mlodzianoski, M. J., Cheng-Hathaway, P. J., Bemiller, S. M., McCray, T. J., Liu, S., Miller, D. A., Lamb, B., Landreth, G. E. & Huang, F., Jul 16 2018, (Accepted/In press) In : Nature Methods. p. 1-4 4 p.

Research output: Contribution to journalArticle

Adaptive optics
Amyloid
Microscopy
Brain
Microscopic examination
220 Citations (Scopus)
Iodoacetates
Yersinia
Protein Tyrosine Phosphatases
Histidine
Labeling

Active skepticism: Beyond the IOM's CTSA report

Shekhar, A., Apr 16 2014, In : Science Translational Medicine. 6, 232, 232ed8.

Research output: Contribution to journalArticle

Health Planning Guidelines
National Academies of Science, Engineering, and Medicine (U.S.) Health and Medicine Division
Translational Medical Research
30 Citations (Scopus)

Active smokingmay negatively affect response rate, progression-free survival, and overall survival of patients with metastatic renal cell carcinoma treatedwith sunitinib

Keizman, D., Gottfried, M., Ish-Shalom, M., Maimon, N., Peer, A., Neumann, A., Hammers, H., Eisenberger, M. A., Sinibaldi, V., Pili, R., Hayat, H., Kovel, S., Sella, A., Boursi, B., Weitzen, R., Mermershtain, W., Rouvinov, K., Berger, R. & Carducci, M. A., 2014, In : Oncologist. 19, 1, p. 51-60 10 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Disease-Free Survival
Smoking
Survival
Hypertension
21 Citations (Scopus)

Active sonic hedgehog signaling between androgen independent human prostate cancer cells and normal/benign but not cancer-associated prostate stromal cells

Shigemura, K., Huang, W. C., Li, X., Zhau, H. E., Zhu, G., Gotoh, A., Fujisawa, M., Xie, J., Marshall, F. F. & Chung, L. W. K., Dec 2011, In : Prostate. 71, 16, p. 1711-1722 12 p.

Research output: Contribution to journalArticle

Hedgehogs
Stromal Cells
Androgens
Prostatic Neoplasms
Osteonectin
5 Citations (Scopus)

Active surveillance for low-risk prostate cancer

Mazzucchelli, R., Nesseris, I., Cheng, L., Lopez-Beltran, A., Montironi, R. & Scarpelli, M., 2010, In : Anticancer Research. 30, 9, p. 3683-3692 10 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Therapeutics
Radiotherapy
Quality of Life
Delivery of Health Care
98 Citations (Scopus)

Active surveillance is the preferred approach to clinical stage i testicular cancer

Nichols, C. R., Roth, B., Albers, P., Einhorn, L., Foster, R., Daneshmand, S., Jewett, M., Warde, P., Sweeney, C. J., Beard, C., Powles, T., Tyldesley, S., So, A., Porter, C., Olgac, S., Fizazi, K., Hayes-Lattin, B., Grimison, P., Toner, G., Cathomas, R. & 2 others, Bokemeyer, C. & Kollmannsberger, C., Oct 1 2013, In : Journal of Clinical Oncology. 31, 28, p. 3490-3493 4 p.

Research output: Contribution to journalArticle

Population Surveillance
Physicians' Practice Patterns
Watchful Waiting
Neoplasm Staging
Testicular Neoplasms
696 Citations (Scopus)

Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine

Stearns, V., Johnson, M. D., Rae, J., Morocho, A., Novielli, A., Bhargava, P., Hayes, D. F., Desta, Z. & Flockhart, D. A., Dec 3 2003, In : Journal of the National Cancer Institute. 95, 23, p. 1758-1764 7 p.

Research output: Contribution to journalArticle

Paroxetine
Serotonin Uptake Inhibitors
Tamoxifen
Cytochrome P-450 CYP2D6
Cytochrome P-450 Enzyme System
24 Citations (Scopus)

Active trafficking of alpha 1 antitrypsin across the lung endothelium

Lockett, A., Brown, M. B., Santos-Falcon, N., Rush, N. I., Oueini, H., Oberle, A. J., Bolanis, E., Fragoso, M. A., Petrusca, D., Serban, K. A., Schweitzer, K. S., Presson, R., Campos, M. & Petrache, I., Apr 17 2014, In : PLoS One. 9, 4, e93979.

Research output: Contribution to journalArticle

alpha 1-Antitrypsin
endothelium
Endothelium
lungs
Lung
12 Citations (Scopus)

Active Tuberculosis Is Associated with Worse Clinical Outcomes in HIV-Infected African Patients on Antiretroviral Therapy

Siika, A. M., Yiannoutsos, C., Wools-Kaloustian, K., Musick, B. S., Mwangi, A. W., Diero, L. O., Kimaiyo, S. N., Tierney, W. M. & Carter, J. E., Jan 2 2013, In : PLoS One. 8, 1, e53022.

Research output: Contribution to journalArticle

tuberculosis
Tuberculosis
HIV
therapeutics
CD4 Lymphocyte Count
39 Citations (Scopus)

Activin acutely sensitizes dorsal root ganglion neurons and induces hyperalgesia via PKC-mediated potentiation of transient receptor potential vanilloid I

Zhu, W., Xu, P., Cuascut, F. X., Hall, A. K. & Oxford, G. S., Dec 12 2007, In : Journal of Neuroscience. 27, 50, p. 13770-13780 11 p.

Research output: Contribution to journalArticle

TRPV Cation Channels
Activins
Hyperalgesia
Spinal Ganglia
Sensory Receptor Cells
43 Citations (Scopus)

Activin-Like Kinase 2 Functions in Peri-implantation Uterine Signaling in Mice and Humans

Clementi, C., Tripurani, S. K., Large, M. J., Edson, M. A., Creighton, C. J., Hawkins, S., Kovanci, E., Kaartinen, V., Lydon, J. P., Pangas, S. A., DeMayo, F. J. & Matzuk, M. M., Nov 2013, In : PLoS Genetics. 9, 11, e1003863.

Research output: Contribution to journalArticle

activins
Activins
bone morphogenetic proteins
stromal cells
Stromal Cells
5 Citations (Scopus)

Activities derived from established human myeloid cell lines reverse the suppression of cell line colony formation by lactoferrin and transferrin

Broxmeyer, H., Rubin, B. Y., Berman, E., Juliano, L., Lu, L., Hast, L. J., Cooper, S. & Singer, J. W., 1986, In : Experimental Hematology. 14, 1, p. 51-59 9 p.

Research output: Contribution to journalArticle

Lactoferrin
Myeloid Cells
Transferrin
Conditioned Culture Medium
Cell Line
38 Citations (Scopus)

Activities of branched-chain amino acid aminotransferase and branched-chain 2-oxo acid dehydrogenase complex in tissues of maternal and fetal sheep

Goodwin, G. W., Gibboney, W., Paxton, R., Harris, R. & Lemons, J. A., 1987, In : Biochemical Journal. 242, 1, p. 305-308 4 p.

Research output: Contribution to journalArticle

3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)
Muscle
Sheep
Fetus
Liver
45 Citations (Scopus)

Activities of the semisynthetic glycopeptide LY191145 against vancomycin- resistant enterococci and other gram-positive bacteria

Nicas, T. I., Mullen, D. L., Flokowitsch, J. E., Preston, D. A., Snyder, N. J., Stratford Jr., R. & Cooper, R. D. G., Jan 1 1995, In : Antimicrobial Agents and Chemotherapy. 39, 11, p. 2585-2587 3 p.

Research output: Contribution to journalArticle

Glycopeptides
Gram-Positive Bacteria
Teicoplanin
chloroorienticin A
Anti-Bacterial Agents
521 Citations (Scopus)

Activity and connectivity of brain mood regulating circuit in depression: A functional magnetic resonance study

Anand, A., Li, Y., Wang, Y., Wu, J., Gao, S., Bukhari, L., Mathews, V., Kalnin, A. & Lowe, M. J., May 15 2005, In : Biological Psychiatry. 57, 10, p. 1079-1088 10 p.

Research output: Contribution to journalArticle

Magnetic Resonance Spectroscopy
Depression
Gyrus Cinguli
Brain
Healthy Volunteers
4 Citations (Scopus)

Activity and enhancer binding factors for BK virus regulatory elements in differentiating embryonal carcinoma cells

Nakshatri, H., Pater, M. M. & Pater, A., 1991, In : Virology. 183, 1, p. 374-380 7 p.

Research output: Contribution to journalArticle

BK Virus
Embryonal Carcinoma Stem Cells
Dimethyl Sulfoxide
Tretinoin
Transcription Factors
16 Citations (Scopus)

Activity and enhancer binding factors for jc virus regulatory elements in differentiating embryonal carcinoma cells

Nakshatri, H., Pater, A. & Pater, M. M., 1990, In : Virology. 177, 2, p. 784-789 6 p.

Research output: Contribution to journalArticle

NFI Transcription Factors
Embryonal Carcinoma Stem Cells
JC Virus
TATA Box
Dimethyl Sulfoxide