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  • Howard Edenberg
2013

Genetics of Alcohol Use Disorders

Edenberg, H. J., Aug 27 2013, Biological Research on Addiction. Elsevier Inc., p. 499-508 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations
2014

Genetic influences on alcohol use across stages of development: GABRA2 and longitudinal trajectories of drunkenness from adolescence to young adulthood

Dick, D. M., Cho, S. B., Latendresse, S. J., Aliev, F., Nurnberger, J. I., Edenberg, H. J., Schuckit, M., Hesselbrock, V. M., Porjesz, B., Bucholz, K., Wang, J. C., Goate, A., Kramer, J. R. & Kuperman, S., Nov 1 2014, In : Addiction Biology. 19, 6, p. 1055-1064 10 p.

Research output: Contribution to journalArticle

30 Scopus citations
2019

How Much Do You Drink on Your Heavy Drinking Day?

Edenberg, H. J., Sep 1 2019, In : Biological psychiatry. 86, 5, p. 330-332 3 p.

Research output: Contribution to journalComment/debate

2013

Loss of metabotropic glutamate receptor 2 escalates alcohol consumption

Zhou, Z., Karlsson, C., Liang, T., Xiong, W., Kimura, M., Tapocik, J. D., Yuan, Q., Barbier, E., Feng, A., Flanigan, M., Augier, E., Enoch, M. A., Hodgkinson, C. A., Shen, P. H., Lovinger, D. M., Edenberg, H. J., Heilig, M. & Goldman, D., Oct 15 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 42, p. 16963-16968 6 p.

Research output: Contribution to journalArticle

67 Scopus citations
2019

Positive and negative reinforcement are differentially associated with alcohol consumption as a function of alcohol dependence

Cho, S. B., Su, J., Kuo, S. I. C., Bucholz, K. K., Chan, G., Edenberg, H. J., McCutcheon, V. V., Schuckit, M. A., Kramer, J. R. & Dick, D. M., Feb 1 2019, In : Psychology of Addictive Behaviors. 33, 1, p. 58-68 11 p.

Research output: Contribution to journalArticle

8 Scopus citations
2013

Cortical-striatal gene expression in neonatal hippocampal lesion (NVHL)-amplified cocaine sensitization

Chambers, R. A., Mcclintick, J. N., Sentir, A. M., Berg, S. A., Runyan, M., Choi, K. H. & Edenberg, H. J., Jul 1 2013, In : Genes, Brain and Behavior. 12, 5, p. 564-575 12 p.

Research output: Contribution to journalArticle

13 Scopus citations
2020

Characterization of Service Use for Alcohol Problems Across Generations and Sex in Adults With Alcohol Use Disorder

Bourdon, J. L., Tillman, R., Francis, M. W., Dick, D. M., Stephenson, M., Kamarajan, C., Edenberg, H. J., Kramer, J., Kuperman, S., Bucholz, K. K. & McCutcheon, V. V., Mar 1 2020, In : Alcoholism: Clinical and Experimental Research. 44, 3, p. 746-757 12 p.

Research output: Contribution to journalArticle

1 Scopus citations
2011

Convergent functional genomic studies of omega-3 fatty acids in stress reactivity, bipolar disorder and alcoholism

Le-Niculescu, H., Case, N. J., Hulvershorn, L., Patel, S. D., Bowker, D., Gupta, J., Bell, R., Edenberg, H. J., Tsuang, M. T., Kuczenski, R., Geyer, M. A., Rodd, Z. A. & Niculescu, A. B., Apr 1 2011, In : Translational psychiatry. 1, e4.

Research output: Contribution to journalArticle

27 Scopus citations
2017

A KCNJ6 gene polymorphism modulates theta oscillations during reward processing

Kamarajan, C., Pandey, A. K., Chorlian, D. B., Manz, N., Stimus, A. T., Edenberg, H. J., Wetherill, L., Schuckit, M., Wang, J. C., Kuperman, S., Kramer, J., Tischfield, J. A. & Porjesz, B., May 1 2017, In : International Journal of Psychophysiology. 115, p. 13-23 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
2014

An enhancer-blocking element regulates the cell-specific expression of alcohol dehydrogenase 7

Jairam, S. & Edenberg, H. J., Sep 1 2014, In : Gene. 547, 2, p. 239-244 6 p.

Research output: Contribution to journalArticle

3 Scopus citations
2012

Genome-wide association study of comorbid depressive syndrome and alcohol dependence

Edwards, A. C., Aliev, F., Bierut, L. J., Bucholz, K. K., Edenberg, H., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger, J. I., Schuckit, M. A., Porjesz, B. & Dick, D. M., Feb 1 2012, In : Psychiatric genetics. 22, 1, p. 31-41 11 p.

Research output: Contribution to journalArticle

69 Scopus citations
2017

Using Patterns of Genetic Association to Elucidate Shared Genetic Etiologies Across Psychiatric Disorders

Cho, S. B., Aliev, F., Clark, S. L., Adkins, A. E., Edenberg, H. J., Bucholz, K. K., Porjesz, B. & Dick, D. M., Jul 1 2017, In : Behavior Genetics. 47, 4, p. 405-415 11 p.

Research output: Contribution to journalArticle

1 Scopus citations
2016

CHRNA5/A3/B4 variant rs3743078 and nicotine-related phenotypes: Indirect effects through nicotine craving

Shmulewitz, D., Meyers, J. L., Wall, M. M., Aharonovich, E., Frisch, A., Spivak, B., Weizman, A., Edenberg, H., Gelernter, J. & Hasin, D. S., Mar 1 2016, In : Journal of Studies on Alcohol and Drugs. 77, 2, p. 227-237 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
2015

Further analyses of genetic association between GRM8 and alcohol dependence symptoms among young adults

Long, E. C., Aliev, A., Wang, J. C., Edenberg, H. J., Nurnberger, J., Hesselbrock, V., Porjesz, B. & Dick, D. M., May 1 2015, In : Journal of studies on alcohol and drugs. 76, 3, p. 414-418 5 p.

Research output: Contribution to journalArticle

9 Scopus citations
2012

Gene expression in the ventral tegmental area of 5 pairs of rat lines selectively bred for high or low ethanol consumption

McBride, W. J., Kimpel, M. W., McClintick, J. N., Ding, Z. M., Hyytia, P., Colombo, G., Edenberg, H. J., Lumeng, L. & Bell, R. L., Aug 1 2012, In : Pharmacology Biochemistry and Behavior. 102, 2, p. 275-285 11 p.

Research output: Contribution to journalArticle

36 Scopus citations
2015

Positive selection on loci associated with drug and alcohol dependence

Sadler, B., Haller, G., Edenberg, H., Tischfield, J., Brooks, A., Kramer, J., Schuckit, M., Nurnberger, J. & Goate, A., Aug 13 2015, In : PloS one. 10, 8, e0134393.

Research output: Contribution to journalArticle

4 Scopus citations
2011

Association of alcohol dehydrogenase genes with alcohol-related phenotypes in a native american community sample

Gizer, I. R., Edenberg, H. J., Gilder, D. A., Wilhelmsen, K. C. & Ehlers, C. L., Nov 2011, In : Alcoholism: Clinical and Experimental Research. 35, 11, p. 2008-2018 11 p.

Research output: Contribution to journalArticle

27 Scopus citations
2018

Psychiatric genomics: An update and an Agenda

Psychiatric Genomics Consortium Coordinating Committee, Jan 1 2018, In : American Journal of Psychiatry. 175, 1, p. 15-27 13 p.

Research output: Contribution to journalArticle

163 Scopus citations
2019

Evidence of causal effect of major depression on alcohol dependence: Findings from the psychiatric genomics consortium

Polimanti, R., Peterson, R. E., Ong, J. S., MacGregor, S., Edwards, A. C., Clarke, T. K., Frank, J., Gerring, Z., Gillespie, N. A., Lind, P. A., Maes, H. H., Martin, N. G., Mbarek, H., Medland, S. E., Streit, F., Agrawal, A., Edenberg, H. J., Kendler, K. S., Lewis, C. M., Sullivan, P. F. & 3 others, Wray, N. R., Gelernter, J. & Derks, E. M., May 1 2019, In : Psychological Medicine. 49, 7, p. 1218-1226 9 p.

Research output: Contribution to journalArticle

12 Scopus citations
2014

Alcohol consumption mediates the relationship between ADH1B and DSM-IV alcohol use disorder and criteria

Kilcoyne, B., Shmulewitz, D., Meyers, J. L., Aharonovich, E., Greenstein, E., Frisch, A., Weizman, A., Spivak, B., Edenberg, H. J., Gelernter, J. & Hasin, D. S., Jul 1 2014, In : Journal of studies on alcohol and drugs. 75, 4, p. 635-642 8 p.

Research output: Contribution to journalArticle

7 Scopus citations
2015

Rare variants in neuronal excitability genes influence risk for bipolar disorder

The Bipolar Genome Study, Mar 17 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 11, p. 3576-3581 6 p.

Research output: Contribution to journalArticle

83 Scopus citations
2014

Variants near CHRNB3-CHRNA6 are associated with DSM-5 cocaine use disorder: Evidence for pleiotropy

Sadler, B., Haller, G., Agrawal, A., Culverhouse, R., Bucholz, K., Brooks, A., Tischfield, J., Johnson, E. O., Edenberg, H., Schuckit, M., Saccone, N., Bierut, L. & Goate, A., Mar 28 2014, In : Scientific reports. 4, 4497.

Research output: Contribution to journalArticle

8 Scopus citations
2017

Reciprocal relationships between substance use and disorders and suicidal ideation and suicide attempts in the Collaborative Study of the Genetics of Alcoholism

Agrawal, A., Tillman, R., Grucza, R. A., Nelson, E. C., McCutcheon, V. V., Few, L., Conner, K. R., Lynskey, M. T., Dick, D. M., Edenberg, H. J., Hesselbrock, V. M., Kramer, J. R., Kuperman, S., Nurnberger, J. I., Schuckit, M. A., Porjesz, B. & Bucholz, K. K., Apr 15 2017, In : Journal of Affective Disorders. 213, p. 96-104 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
2016

Translating genome-wide association findings into new therapeutics for psychiatry

Breen, G., Li, Q., Roth, B. L., O'Donnell, P., Didriksen, M., Dolmetsch, R., O'Reilly, P. F., Gaspar, H. A., Manji, H., Huebel, C., Kelsoe, J. R., Malhotra, D., Bertolino, A., Posthuma, D., Sklar, P., Kapur, S., Sullivan, P. F., Collier, D. A. & Edenberg, H. J., Oct 26 2016, In : Nature Neuroscience. 19, 11, p. 1392-1396 5 p.

Research output: Contribution to journalReview article

65 Scopus citations
2020

A Family-Based Genome Wide Association Study of Externalizing Behaviors

Barr, P. B., Salvatore, J. E., Wetherill, L., Anokhin, A., Chan, G., Edenberg, H. J., Kuperman, S., Meyers, J., Nurnberger, J., Porjesz, B., Schuckit, M. & Dick, D. M., May 1 2020, In : Behavior Genetics. 50, 3, p. 175-183 9 p.

Research output: Contribution to journalArticle

2015

Are genetic variants for tobacco smoking associated with cannabis involvement?

Agrawal, A., Lynskey, M. T., Kapoor, M., Bucholz, K. K., Edenberg, H. J., Schuckit, M., Brooks, A., Hesselbrock, V., Kramer, J., Saccone, N., Tischfield, J. & Bierut, L. J., May 1 2015, In : Drug and Alcohol Dependence. 150, p. 183-187 5 p.

Research output: Contribution to journalArticle

7 Scopus citations
2012

Measuring alcohol consumption for genomic meta-analyses of alcohol intake: Opportunities and challenges

Agrawal, A., Freedman, N. D., Cheng, Y. C., Lin, P., Shaffer, J. R., Sun, Q., Taylor, K., Yaspan, B., Cole, J. W., Cornelis, M. C., DeSensi, R. S., Fitzpatrick, A., Heiss, G., Kang, J. H., O'Connell, J., Bennett, S., Bookman, E., Bucholz, K. K., Caporaso, N., Crout, R. & 18 others, Dick, D. M., Edenberg, H. J., Goate, A., Hesselbrock, V., Kittner, S., Kramer, J., Nurnberger, J. I., Qi, L., Rice, J. P., Schuckit, M., Van Dam, R. M., Boerwinkle, E., Hu, F., Levy, S., Marazita, M., Mitchell, B. D., Pasquale, L. R. & Bierut, L. J., Mar 1 2012, In : American Journal of Clinical Nutrition. 95, 3, p. 539-547 9 p.

Research output: Contribution to journalReview article

27 Scopus citations
2011

McMahon et al. reply

McMahon, F. J., Akula, N., Cichon, S., Detera-Wadleigh, S. D., Edenberg, H., Holsboer, F., Nöthen, M. M., Nurnberger, J. I., Potash, J., Preisig, M., Rietschel, M. & Schulze, T. G., Jan 1 2011, In : Nature genetics. 43, 1, 1 p.

Research output: Contribution to journalLetter

2012

CHRNB3 is more strongly associated with Fagerström Test for Cigarette Dependence-based nicotine dependence than cigarettes per day: Phenotype definition changes genome-wide association studies results

Rice, J. P., Hartz, S. M., Agrawal, A., Almasy, L., Bennett, S., Breslau, N., Bucholz, K. K., Doheny, K. F., Edenberg, H. J., Goate, A. M., Hesselbrock, V., Howells, W. B., Johnson, E. O., Kramer, J., Krueger, R. F., Kuperman, S., Laurie, C., Manolio, T. A., Neuman, R. J., Nurnberger, J. I. & 7 others, Porjesz, B., Pugh, E., Ramos, E. M., Saccone, N., Saccone, S., Schuckit, M. & Bierut, L. J., Nov 1 2012, In : Addiction. 107, 11, p. 2019-2028 10 p.

Research output: Contribution to journalArticle

51 Scopus citations
2017

Familial association of abstinent remission from alcohol use disorder in first-degree relatives of alcohol-dependent treatment-seeking probands

McCutcheon, V. V., Schuckit, M. A., Kramer, J. R., Chan, G., Edenberg, H. J., Smith, T. L., Bender, A. K., Hesselbrock, V., Hesselbrock, M. & Bucholz, K. K., Nov 2017, In : Addiction. 112, 11, p. 1909-1917 9 p.

Research output: Contribution to journalArticle

6 Scopus citations
2014

Ethanol treatment of lymphoblastoid cell lines from alcoholics and non-alcoholics causes many subtle changes in gene expression

McClintick, J. N., Brooks, A. I., Deng, L., Liang, L., Wang, J. C., Kapoor, M., Xuei, X., Foroud, T., Tischfield, J. A. & Edenberg, H. J., Sep 1 2014, In : Alcohol. 48, 6, p. 603-610 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
2015
7 Scopus citations
2020

A genome-wide association study of interhemispheric theta EEG coherence: implications for neural connectivity and alcohol use behavior

Meyers, J. L., Zhang, J., Chorlian, D. B., Pandey, A. K., Kamarajan, C., Wang, J. C., Wetherill, L., Lai, D., Chao, M., Chan, G., Kinreich, S., Kapoor, M., Bertelsen, S., McClintick, J., Bauer, L., Hesselbrock, V., Kuperman, S., Kramer, J., Salvatore, J. E., Dick, D. M. & 5 others, Agrawal, A., Foroud, T., Edenberg, H. J., Goate, A. & Porjesz, B., 2020, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies

Munn-Chernoff, M. A., Johnson, E. C., Chou, Y. L., Coleman, J. R. I., Thornton, L. M., Walters, R. K., Yilmaz, Z., Baker, J. H., Hübel, C., Gordon, S., Medland, S. E., Watson, H. J., Gaspar, H. A., Bryois, J., Hinney, A., Leppä, V. M., Mattheisen, M., Ripke, S., Yao, S., Giusti-Rodríguez, P. & 332 others, Hanscombe, K. B., Adan, R. A. H., Alfredsson, L., Ando, T., Andreassen, O. A., Berrettini, W. H., Boehm, I., Boni, C., Boraska Perica, V., Buehren, K., Burghardt, R., Cassina, M., Cichon, S., Clementi, M., Cone, R. D., Courtet, P., Crow, S., Crowley, J. J., Danner, U. N., Davis, O. S. P., de Zwaan, M., Dedoussis, G., Degortes, D., DeSocio, J. E., Dick, D. M., Dikeos, D., Dina, C., Dmitrzak-Weglarz, M., Docampo, E., Duncan, L. E., Egberts, K., Ehrlich, S., Escaramís, G., Esko, T., Estivill, X., Farmer, A., Favaro, A., Fernández-Aranda, F., Fichter, M. M., Fischer, K., Föcker, M., Foretova, L., Forstner, A. J., Forzan, M., Franklin, C. S., Gallinger, S., Giegling, I., Giuranna, J., Gonidakis, F., Gorwood, P., Gratacos Mayora, M., Guillaume, S., Guo, Y., Hakonarson, H., Hatzikotoulas, K., Hauser, J., Hebebrand, J., Helder, S. G., Herms, S., Herpertz-Dahlmann, B., Herzog, W., Huckins, L. M., Hudson, J. I., Imgart, H., Inoko, H., Janout, V., Jiménez-Murcia, S., Julià, A., Kalsi, G., Kaminská, D., Karhunen, L., Karwautz, A., Kas, M. J. H., Kennedy, J. L., Keski-Rahkonen, A., Kiezebrink, K., Kim, Y. R., Klump, K. L., Knudsen, G. P. S., La Via, M. C., Le Hellard, S., Levitan, R. D., Li, D., Lilenfeld, L., Lin, B. D., Lissowska, J., Luykx, J., Magistretti, P. J., Maj, M., Mannik, K., Marsal, S., Marshall, C. R., Mattingsdal, M., McDevitt, S., McGuffin, P., Metspalu, A., Meulenbelt, I., Micali, N., Mitchell, K., Monteleone, A. M., Monteleone, P., Nacmias, B., Navratilova, M., Ntalla, I., O'Toole, J. K., Ophoff, R. A., Padyukov, L., Palotie, A., Pantel, J., Papezova, H., Pinto, D., Rabionet, R., Raevuori, A., Ramoz, N., Reichborn-Kjennerud, T., Ricca, V., Ripatti, S., Ritschel, F., Roberts, M., Rotondo, A., Rujescu, D., Rybakowski, F., Santonastaso, P., Scherag, A., Scherer, S. W., Schmidt, U., Schork, N. J., Schosser, A., Seitz, J., Slachtova, L., Slagboom, P. E., Slof-Op't Landt, M. C. T., Slopien, A., Sorbi, S., Świątkowska, B., Szatkiewicz, J. P., Tachmazidou, I., Tenconi, E., Tortorella, A., Tozzi, F., Treasure, J., Tsitsika, A., Tyszkiewicz-Nwafor, M., Tziouvas, K., van Elburg, A. A., van Furth, E. F., Wagner, G., Walton, E., Widen, E., Zeggini, E., Zerwas, S., Zipfel, S., Bergen, A. W., Boden, J. M., Brandt, H., Crawford, S., Halmi, K. A., Horwood, L. J., Johnson, C., Kaplan, A. S., Kaye, W. H., Mitchell, J., Olsen, C. M., Pearson, J. F., Pedersen, N. L., Strober, M., Werge, T., Whiteman, D. C., Woodside, D. B., Grove, J., Henders, A. K., Larsen, J. T., Parker, R., Petersen, L. V., Jordan, J., Kennedy, M. A., Birgegård, A., Lichtenstein, P., Norring, C., Landén, M., Mortensen, P. B., Polimanti, R., McClintick, J. N., Adkins, A. E., Aliev, F., Bacanu, S. A., Batzler, A., Bertelsen, S., Biernacka, J. M., Bigdeli, T. B., Chen, L. S., Clarke, T. K., Degenhardt, F., Docherty, A. R., Edwards, A. C., Foo, J. C., Fox, L., Frank, J., Hack, L. M., Hartmann, A. M., Hartz, S. M., Heilmann-Heimbach, S., Hodgkinson, C., Hoffmann, P., Hottenga, J. J., Konte, B., Lahti, J., Lahti-Pulkkinen, M., Lai, D., Ligthart, L., Loukola, A., Maher, B. S., Mbarek, H., McIntosh, A. M., McQueen, M. B., Meyers, J. L., Milaneschi, Y., Palviainen, T., Peterson, R. E., Ryu, E., Saccone, N. L., Salvatore, J. E., Sanchez-Roige, S., Schwandt, M., Sherva, R., Streit, F., Strohmaier, J., Thomas, N., Wang, J. C., Webb, B. T., Wedow, R., Wetherill, L., Wills, A. G., Zhou, H., Boardman, J. D., Chen, D., Choi, D. S., Copeland, W. E., Culverhouse, R. C., Dahmen, N., Degenhardt, L., Domingue, B. W., Frye, M. A., Gäbel, W., Hayward, C., Ising, M., Keyes, M., Kiefer, F., Koller, G., Kramer, J., Kuperman, S., Lucae, S., Lynskey, M. T., Maier, W., Mann, K., Männistö, S., Müller-Myhsok, B., Murray, A. D., Nurnberger, J. I., Preuss, U., Räikkönen, K., Reynolds, M. D., Ridinger, M., Scherbaum, N., Schuckit, M. A., Soyka, M., Treutlein, J., Witt, S. H., Wodarz, N., Zill, P., Adkins, D. E., Boomsma, D. I., Bierut, L. J., Brown, S. A., Bucholz, K. K., Costello, E. J., de Wit, H., Diazgranados, N., Eriksson, J. G., Farrer, L. A., Foroud, T. M., Gillespie, N. A., Goate, A. M., Goldman, D., Grucza, R. A., Hancock, D. B., Harris, K. M., Hesselbrock, V., Hewitt, J. K., Hopfer, C. J., Iacono, W. G., Johnson, E. O., Karpyak, V. M., Kendler, K. S., Kranzler, H. R., Krauter, K., Lind, P. A., McGue, M., MacKillop, J., Madden, P. A. F., Maes, H. H., Magnusson, P. K. E., Nelson, E. C., Nöthen, M. M., Palmer, A. A., Penninx, B. W. J. H., Porjesz, B., Rice, J. P., Rietschel, M., Riley, B. P., Rose, R. J., Shen, P. H., Silberg, J., Stallings, M. C., Tarter, R. E., Vanyukov, M. M., Vrieze, S., Wall, T. L., Whitfield, J. B., Zhao, H., Neale, B. M., Wade, T. D., Heath, A. C., Montgomery, G. W., Martin, N. G., Sullivan, P. F., Kaprio, J., Breen, G., Gelernter, J., Edenberg, H. J., Bulik, C. M. & Agrawal, A., 2020, (Accepted/In press) In : Addiction Biology. e12880.

Research output: Contribution to journalArticle

2017

Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence

Andersen, A. M., Pietrzak, R. H., Kranzler, H. R., Ma, L., Zhou, H., Liu, X., Kramer, J., Kuperman, S., Edenberg, H. J., Nurnberger, J. I., Rice, J. P., Tischfield, J. A., Goate, A., Foroud, T. M., Meyers, J. L., Porjesz, B., Dick, D. M., Hesselbrock, V., Boerwinkle, E., Southwick, S. M. & 6 others, Krystal, J. H., Weissman, M. M., Levinson, D. F., Potash, J. B., Gelernter, J. & Han, S., Nov 1 2017, In : JAMA psychiatry. 74, 11, p. 1153-1160 8 p.

Research output: Contribution to journalArticle

26 Scopus citations
2011

Genetic association of bipolar disorder with the β3 nicotinic receptor subunit gene

Hartz, S. M., Lin, P., Edenberg, H. J., Xuei, X., Rochberg, N., Saccone, S., Berrettini, W., Nelson, E., Nurnberger, J., Bierut, L. J., Rice, J. P., Miller, M. J., Bowman, E. S., Rau, N. L., Moe, P. R., Samavedy, N., El-Mallakh, R., Manji, H., Glitz, D. A., Meyer, E. T. & 42 others, Smiley, C., Foroud, T., Flury, L., Dick, D. M., Reich, T., Goate, A., McInnis, M., DePaulo, J. R., MacKinnon, D. F., Mondimore, F. M., Potash, J. B., Zandi, P. P., Avramopoulos, D., Payne, J., Byerley, W., Vinogradov, S., Coryell, W., Crowe, R., Gershon, E., Badner, J., McMahon, F., Liu, C., Sanders, A., Caserta, M., Dinwiddie, S., Nguyen, T., Harakal, D., Kelsoe, J., McKinney, R., Scheftner, W., Kravitz, H. M., Marta, D., Vaughn-Brown, A., Bederow, L., McMahon, F. J., Kassem, L., Detera-Wadleigh, S., Austin, L., Murphy, D. L., Lawson, W. B., Nwulia, E. & Hipolito, M., Apr 2011, In : Psychiatric genetics. 21, 2, p. 77-84 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
2013

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking

Stephens, S. H., Hartz, S. M., Hoft, N. R., Saccone, N. L., Corley, R. C., Hewitt, J. K., Hopfer, C. J., Breslau, N., Coon, H., Chen, X., Ducci, F., Dueker, N., Franceschini, N., Frank, J., Han, Y., Hansel, N. N., Jiang, C., Korhonen, T., Lind, P. A., Liu, J. & 106 others, Lyytikäinen, L. P., Michel, M., Shaffer, J. R., Short, S. E., Sun, J., Teumer, A., Thompson, J. R., Vogelzangs, N., Vink, J. M., Wenzlaff, A., Wheeler, W., Yang, B. Z., Aggen, S. H., Balmforth, A. J., Baumeister, S. E., Beaty, T. H., Benjamin, D. J., Bergen, A. W., Broms, U., Cesarini, D., Chatterjee, N., Chen, J., Cheng, Y. C., Cichon, S., Couper, D., Cucca, F., Dick, D., Foroud, T., Furberg, H., Giegling, I., Gillespie, N. A., Gu, F., Hall, A. S., Hällfors, J., Han, S., Hartmann, A. M., Heikkilä, K., Hickie, I. B., Hottenga, J. J., Jousilahti, P., Kaakinen, M., Kähönen, M., Koellinger, P. D., Kittner, S., Konte, B., Landi, M. T., Laatikainen, T., Leppert, M., Levy, S. M., Mathias, R. A., Mcneil, D. W., Medland, S. E., Montgomery, G. W., Murray, T., Nauck, M., North, K. E., Paré, P. D., Pergadia, M., Ruczinski, I., Salomaa, V., Viikari, J., Willemsen, G., Barnes, K. C., Boerwinkle, E., Boomsma, D. I., Caporaso, N., Edenberg, H. J., Francks, C., Gelernter, J., Grabe, H. J., Hops, H., Jarvelin, M. R., Johannesson, M., Kendler, K. S., Lehtimäki, T., Magnusson, P. K. E., Marazita, M. L., Marchini, J., Mitchell, B. D., Nöthen, M. M., Penninx, B. W., Raitakari, O., Rietschel, M., Rujescu, D., Samani, N. J., Schwartz, A. G., Shete, S., Spitz, M., Swan, G. E., Völzke, H., Veijola, J., Wei, Q., Amos, C., Cannon, D. S., Grucza, R., Hatsukami, D., Heath, A., Johnson, E. O., Kaprio, J., Madden, P., Martin, N. G., Stevens, V. L., Weiss, R. B., Kraft, P., Bierut, L. J. & Ehringer, M. A., Dec 2013, In : Genetic epidemiology. 37, 8, p. 846-859 14 p.

Research output: Contribution to journalArticle

28 Scopus citations
2016

Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts

Schwantes-An, T. H., Zhang, J., Chen, L. S., Hartz, S. M., Culverhouse, R. C., Chen, X., Coon, H., Frank, J., Kamens, H. M., Konte, B., Kovanen, L., Latvala, A., Legrand, L. N., Maher, B. S., Melroy, W. E., Nelson, E. C., Reid, M. W., Robinson, J. D., Shen, P. H., Yang, B. Z. & 90 others, Andrews, J. A., Aveyard, P., Beltcheva, O., Brown, S. A., Cannon, D. S., Cichon, S., Corley, R. P., Dahmen, N., Degenhardt, L., Foroud, T., Gaebel, W., Giegling, I., Glatt, S. J., Grucza, R. A., Hardin, J., Hartmann, A. M., Heath, A. C., Herms, S., Hodgkinson, C. A., Hoffmann, P., Hops, H., Huizinga, D., Ising, M., Johnson, E. O., Johnstone, E., Kaneva, R. P., Kendler, K. S., Kiefer, F., Kranzler, H. R., Krauter, K. S., Levran, O., Lucae, S., Lynskey, M. T., Maier, W., Mann, K., Martin, N. G., Mattheisen, M., Montgomery, G. W., Müller-Myhsok, B., Murphy, M. F., Neale, M. C., Nikolov, M. A., Nishita, D., Nöthen, M. M., Nurnberger, J., Partonen, T., Pergadia, M. L., Reynolds, M., Ridinger, M., Rose, R. J., Rouvinen-Lagerström, N., Scherbaum, N., Schmäl, C., Soyka, M., Stallings, M. C., Steffens, M., Treutlein, J., Tsuang, M., Wall, T. L., Wodarz, N., Yuferov, V., Zill, P., Bergen, A. W., Chen, J., Cinciripini, P. M., Edenberg, H. J., Ehringer, M. A., Ferrell, R. E., Gelernter, J., Goldman, D., Hewitt, J. K., Hopfer, C. J., Iacono, W. G., Kaprio, J., Kreek, M. J., Kremensky, I. M., Madden, P. A. F., McGue, M., Munafò, M. R., Philibert, R. A., Rietschel, M., Roy, A., Rujescu, D., Saarikoski, S. T., Swan, G. E., Todorov, A. A., Vanyukov, M. M., Weiss, R. B., Bierut, L. J. & Saccone, N. L., Mar 1 2016, In : Behavior Genetics. 46, 2, p. 151-169 19 p.

Research output: Contribution to journalArticle

53 Scopus citations
2019

Erratum to: Genome-wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward-related ventral striatum activity in African- and European-Americans (Genes, Brain and Behavior, (e12580), 10.1111/gbb.12580)

Wetherill, L., Lai, D., Johnson, E. C., Anokhin, A., Bauer, L., Bucholz, K. K., Dick, D. M., Hariri, A. R., Hesselbrock, V., Kamarajan, C., Kramer, J., Kuperman, S., Meyers, J. L., Nurnberger, J. I., Schuckit, M., Scott, D. M., Taylor, R. E., Tischfield, J., Porjesz, B., Goate, A. M. & 4 others, Edenberg, H. J., Foroud, T., Bogdan, R. & Agrawal, A., Nov 1 2019, In : Genes, Brain and Behavior. 18, 8, e12608.

Research output: Contribution to journalComment/debate

Open Access
2012

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

Hartz, S. M., Short, S. E., Saccone, N. L., Culverhouse, R., Chen, L. S., Schwantes-An, T. H., Coon, H., Han, Y., Stephens, S. H., Sun, J., Chen, X., Ducci, F., Dueker, N., Franceschini, N., Frank, J., Geller, F., Guobjartsson, D., Hansel, N. N., Jiang, C., Keskitalo-Vuokko, K. & 132 others, Liu, Z., Lyytikäinen, L. P., Michel, M., Rawal, R., Rosenberger, A., Scheet, P., Shaffer, J. R., Teumer, A., Thompson, J. R., Vink, J. M., Vogelzangs, N., Wenzlaff, A. S., Wheeler, W., Xiao, X., Yang, B. Z., Aggen, S. H., Balmforth, A. J., Baumeister, S. E., Beaty, T., Bennett, S., Bergen, A. W., Boyd, H. A., Broms, U., Campbell, H., Chatterjee, N., Chen, J., Cheng, Y. C., Cichon, S., Couper, D., Cucca, F., Dick, D. M., Foroud, T., Furberg, H., Giegling, I., Gu, F., Hall, A. S., Hällfors, J., Han, S., Hartmann, A. M., Hayward, C., Heikkilä, K., Hewitt, J. K., Hottenga, J. J., Jensen, M. K., Jousilahti, P., Kaakinen, M., Kittner, S. J., Konte, B., Korhonen, T., Landi, M. T., Laatikainen, T., Leppert, M., Levy, S. M., Mathias, R. A., McNeil, D. W., Medland, S. E., Montgomery, G. W., Muley, T., Murray, T., Nauck, M., North, K., Pergadia, M., Polasek, O., Ramos, E. M., Ripatti, S., Risch, A., Ruczinski, I., Rudan, I., Salomaa, V., Schlessinger, D., Styrkársdóttir, U., Terracciano, A., Uda, M., Willemsen, G., Wu, X., Abecasis, G., Barnes, K., Bickeböller, H., Boerwinkle, E., Boomsma, D. I., Caporaso, N., Duan, J., Edenberg, H. J., Francks, C., Gejman, P. V., Gelernter, J., Grabe, H. J., Hops, H., Jarvelin, M. R., Viikari, J., Kähönen, M., Kendler, K. S., Lehtimäki, T., Levinson, D. F., Marazita, M. L., Marchini, J., Melbye, M., Mitchell, B. D., Murray, J. C., Nöthen, M. M., Penninx, B. W., Raitakari, O., Rietschel, M., Rujescu, D., Samani, N. J., Sanders, A. R., Schwartz, A. G., Shete, S., Shi, J., Spitz, M., Stefansson, K., Swan, G. E., Thorgeirsson, T., Völzke, H., Wei, Q., Wichmann, H. E., Amos, C. I., Breslau, N., Cannon, D. S., Ehringer, M., Grucza, R., Hatsukami, D., Heath, A., Johnson, E. O., Kaprio, J., Madden, P., Martin, N. G., Stevens, V. L., Stitzel, J. A., Weiss, R. B., Kraft, P. & Bierut, L. J., Aug 2012, In : Archives of general psychiatry. 69, 8, p. 854-861 8 p.

Research output: Contribution to journalArticle

48 Scopus citations
2020

Genome-wide association studies of the self-rating of effects of ethanol (SRE)

Lai, D., Wetherill, L., Kapoor, M., Johnson, E. C., Schwandt, M., Ramchandani, V. A., Goldman, D., Joslyn, G., Rao, X., Liu, Y., Farris, S., Mayfield, R. D., Dick, D., Hesselbrock, V., Kramer, J., McCutcheon, V. V., Nurnberger, J., Tischfield, J., Goate, A., Edenberg, H. J. & 4 others, Porjesz, B., Agrawal, A., Foroud, T. & Schuckit, M., Mar 1 2020, In : Addiction Biology. 25, 2, e12800.

Research output: Contribution to journalArticle

1 Scopus citations
2019

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 2019, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2015

Peroxisome Proliferator-Activated Receptors α and γ are Linked with Alcohol Consumption in Mice and Withdrawal and Dependence in Humans

Blednov, Y. A., Benavidez, J. M., Black, M., Ferguson, L. B., Schoenhard, G. L., Goate, A. M., Edenberg, H. J., Wetherill, L., Hesselbrock, V., Foroud, T. & Adron Harris, R., Jan 1 2015, In : Alcoholism: Clinical and Experimental Research. 39, 1, p. 136-145 10 p.

Research output: Contribution to journalArticle

55 Scopus citations
2014

Complex Genetics of Alcoholism

Edenberg, H. J. & Foroud, T., Feb 2014, Neurobiology of Alcohol Dependence. Elsevier Inc., p. 539-550 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations
2019

Genome-wide association study identifies 30 loci associated with bipolar disorder

eQTLGen Consortium, BIOS Consortium & the Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, May 1 2019, In : Nature genetics. 51, 5, p. 793-803 11 p.

Research output: Contribution to journalArticle

157 Scopus citations
2017
12 Scopus citations
2012

Regsnps: A strategy for prioritizing regulatory single nucleotide substitutions

Teng, M., Ichikawa, S., Padgett, L. R., Wang, Y., Mort, M., Cooper, D. N., Koller, D. L., Foroud, T., Edenberg, H. J., Econs, M. J. & Liu, Y., Jul 1 2012, In : Bioinformatics. 28, 14, p. 1879-1886 8 p., bts275.

Research output: Contribution to journalArticle

7 Scopus citations
2017

Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms

Collaborative Study of the Genetics of Alcoholism Consortium & the German Study of the Genetics of Addiction Consortium, May 2017, In : Alcoholism: Clinical and Experimental Research. 41, 5, p. 911-928 18 p.

Research output: Contribution to journalArticle

18 Scopus citations

A GABRA2 polymorphism improves a model for prediction of drinking initiation

Kuperman, S., Chan, G., Kramer, J., Wetherill, L., Acion, L., Edenberg, H. J., Foroud, T. M., Nurnberger, J., Agrawal, A., Anokhin, A., Brooks, A., Hesselbrock, V., Hesselbrock, M., Schuckit, M., Tischfield, J. & Liu, X., Sep 2017, In : Alcohol. 63, p. 1-8 8 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, Dec 1 2018, In : Communications Biology. 1, 1, 163.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations