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  • Andrew Saykin
2018

Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study

Gordon, B. A., Blazey, T. M., Su, Y., Hari-Raj, A., Dincer, A., Flores, S., Christensen, J., McDade, E., Wang, G., Xiong, C., Cairns, N. J., Hassenstab, J., Marcus, D. S., Fagan, A. M., Jack, C. R., Hornbeck, R. C., Paumier, K. L., Ances, B. M., Berman, S. B., Brickman, A. M. & 20 others, Cash, D. M., Chhatwal, J. P., Correia, S., Förster, S., Fox, N. C., Graff-Radford, N. R., la Fougère, C., Levin, J., Masters, C. L., Rossor, M. N., Salloway, S., Saykin, A. J., Schofield, P. R., Thompson, P. M., Weiner, M. M., Holtzman, D. M., Raichle, M. E., Morris, J. C., Bateman, R. J. & Benzinger, T. L. S., Mar 2018, In : The Lancet Neurology. 17, 3, p. 241-250 10 p.

Research output: Contribution to journalArticle

74 Scopus citations
2017

Genome-wide network-based pathway analysis of CSF t-tau/Aβ1-42 ratio in the ADNI cohort

for the Alzheimer's Disease Neuroimaging Initiative, May 30 2017, In : BMC genomics. 18, 1, 421.

Research output: Contribution to journalArticle

6 Scopus citations
2019

Interactive Machine Learning by Visualization: A Small Data Solution

Li, H., Fang, S., Mukhopadhyay, S., Saykin, A. J. & Shen, L., Jan 22 2019, Proceedings - 2018 IEEE International Conference on Big Data, Big Data 2018. Song, Y., Liu, B., Lee, K., Abe, N., Pu, C., Qiao, M., Ahmed, N., Kossmann, D., Saltz, J., Tang, J., He, J., Liu, H. & Hu, X. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 3513-3521 9 p. 8621952. (Proceedings - 2018 IEEE International Conference on Big Data, Big Data 2018).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2017

Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies: A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation

Snyder, H. M., Ahles, T., Calderwood, S., Carrillo, M. C., Chen, H., Chang, C. C. H., Craft, S., De Jager, P., Driver, J. A., Fillit, H., Knopman, D., Lotze, M., Tierney, M. C., Petanceska, S., Saykin, A., Seshadri, S., Shineman, D. & Ganguli, M., Mar 1 2017, In : Alzheimer's and Dementia. 13, 3, p. 267-273 7 p.

Research output: Contribution to journalReview article

13 Scopus citations
2015

Diagnostic Value of Subjective Memory Complaints Assessed with a Single Item in Dominantly Inherited Alzheimer's Disease: Results of the DIAN Study

Laske, C., Sohrabi, H. R., Jasielec, M. S., Müller, S., Koehler, N. K., Gräber, S., Förster, S., Drzezga, A., Mueller-Sarnowski, F., Danek, A., Jucker, M., Bateman, R. J., Buckles, V., Saykin, A. J., Martins, R. N. & Morris, J. C., 2015, In : BioMed research international. 2015, 828120.

Research output: Contribution to journalArticle

7 Scopus citations
2012

Identifying disease sensitive and quantitative trait-relevant biomarkers from multidimensional heterogeneous imaging genetics data via sparse multimodal multitask learning

Wang, H., Nie, F., Huang, H., Risacher, S. L., Saykin, A. J. & Shen, L., Jun 1 2012, In : Bioinformatics. 28, 12, p. i127-i136 bts228.

Research output: Contribution to journalArticle

72 Scopus citations
2017

Identification of associations between genotypes and longitudinal phenotypes via temporally-constrained group sparse canonical correlation analysis

Hao, X., Li, C., Yan, J., Yao, X., Risacher, S. L., Saykin, A. J., Shen, L. & Zhang, D., Jul 15 2017, In : Bioinformatics. 33, 14, p. i341-i349

Research output: Contribution to journalArticle

10 Scopus citations
2019

Correction to: Genetic data and cognitively defined late-onset Alzheimer’s disease subgroups (Molecular Psychiatry, (2018), 10.1038/s41380-018-0298-8)

EPAD Study Group, Investigators from ACT, Investigators from ROS, Investigators from MAP, Investigators from ADNI & Investigators from the University of Pittsburgh ADRC, Jan 1 2019, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

1 Scopus citations
2015

The Alzheimer's Disease Neuroimaging Initiative 2 Biomarker Core: A review of progress and plans

Kang, J. H., Korecka, M., Figurski, M. J., Toledo, J. B., Blennow, K., Zetterberg, H., Waligorska, T., Brylska, M., Fields, L., Shah, N., Soares, H., Dean, R. A., Vanderstichele, H., Petersen, R. C., Aisen, P. S., Saykin, A. J., Weiner, M. W., Trojanowski, J. Q. & Shaw, L. M., Jul 1 2015, In : Alzheimer's and Dementia. 11, 7, p. 772-791 20 p.

Research output: Contribution to journalReview article

31 Scopus citations
2018

Volumetric comparison of hippocampal subfields extracted from 4-minute accelerated vs. 8-minute high-resolution T2-weighted 3T MRI scans

Cong, S., Risacher, S. L., West, J. D., Wu, Y. C., Apostolova, L. G., Tallman, E., Rizkalla, M., Salama, P., Saykin, A. J. & Shen, L., Dec 1 2018, In : Brain Imaging and Behavior. 12, 6, p. 1583-1595 13 p.

Research output: Contribution to journalArticle

3 Scopus citations
2015

Surface-based morphometric analysis of hippocampal subfields in mild cognitive impairment and Alzheimer's disease

Cong, S., Rizkalla, M., Salama, P., West, J., Risacher, S., Saykin, A. & Shen, L., Sep 28 2015, IEEE 58th International Midwest Symposium on Circuits and Systems: Climbing to New Heights, MWSCAS 2015 - Conference Proceedings. Institute of Electrical and Electronics Engineers Inc., 7282173. (Midwest Symposium on Circuits and Systems; vol. 2015-September).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations
2014

Longitudinal assessment of cognitive changes associated with adjuvant treatment for breast cancer: The impact of APOE and smoking

Ahles, T. A., Li, Y., McDonald, B. C., Schwartz, G. N., Kaufman, P. A., Tsongalis, G. J., Moore, J. H. & Saykin, A. J., Dec 1 2014, In : Psycho-Oncology. 23, 12, p. 1382-1390 9 p.

Research output: Contribution to journalArticle

35 Scopus citations
2013

Increased CNV-Region deletions in mild cognitive impairment (MCI) and Alzheimer's disease (AD) subjects in the ADNI sample

Guffanti, G., Torri, F., Rasmussen, J., Clark, A. P., Lakatos, A., Turner, J. A., Fallon, J. H., Saykin, A. J., Weiner, M., Vawter, M. P., Knowles, J. A., Potkin, S. G. & Macciardi, F., Aug 2013, In : Genomics. 102, 2, p. 112-122 11 p.

Research output: Contribution to journalReview article

18 Scopus citations
2014

Human connectome module pattern detection using a new multi-graph MinMax cut model.

De, W., Wang, Y., Nie, F., Yan, J., Cai, W., Saykin, A., Shen, L. & Huang, H., 2014, Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. Pt 3 ed. Vol. 17. p. 313-320 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations
2012

fMRI wada test: Prospects for presurgical mapping of language and memory

McDonald, B. C., Kean, J. & Saykin, A. J., Jan 1 2012, Functional Neuroradiology: Principles and Clinical Applications. Springer US, p. 455-484 30 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations
2013

Impaired default network functional connectivity in autosomal dominant Alzheimer disease

Chhatwal, J. P., Schultz, A. P., Johnson, K., Benzinger, T. L. S., Jack, C., Ances, B. M., Sullivan, C. A., Salloway, S. P., Ringman, J. M., Koeppe, R. A., Marcus, D. S., Thompson, P., Saykin, A. J., Correia, S., Schofield, P. R., Rowe, C. C., Fox, N. C., Brickman, A. M., Mayeux, R., McDade, E. & 7 others, Bateman, R., Fagan, A. M., Goate, A. M., Xiong, C., Buckles, V. D., Morris, J. C. & Sperling, R. A., Aug 20 2013, In : Neurology. 81, 8, p. 736-744 9 p.

Research output: Contribution to journalArticle

92 Scopus citations
2016
1 Scopus citations
2018

Detection of tau in Gerstmann-Sträussler-Scheinker disease (PRNP F198S) by [18F]Flortaucipir PET

Risacher, S. L., Farlow, M. R., Bateman, D. R., Epperson, F., Tallman, E. F., Richardson, R., Murrell, J. R., Unverzagt, F. W., Apostolova, L. G., Bonnin, J. M., Ghetti, B. & Saykin, A. J., Oct 29 2018, In : Acta Neuropathologica Communications. 6, 1, p. 114 1 p.

Research output: Contribution to journalArticle

2 Scopus citations
2016

Identifying Multimodal Intermediate Phenotypes Between Genetic Risk Factors and Disease Status in Alzheimer’s Disease

Hao, X., Yao, X., Yan, J., Risacher, S. L., Saykin, A. J., Zhang, D., Shen, L. & for the Alzheimer’s Disease Neuroimaging Initiative, T. A. D. N. I., Oct 1 2016, In : Neuroinformatics. 14, 4, p. 439-452 14 p.

Research output: Contribution to journalArticle

11 Scopus citations
2014

Identifying the neuroanatomical basis of cognitive impairment in Alzheimer's disease by correlation-and nonlinearity-aware sparse bayesian learning

Wan, J., Zhang, Z., Rao, B. D., Fang, S., Yan, J., Saykin, A. J. & Shen, L., Jul 2014, In : IEEE Transactions on Medical Imaging. 33, 7, p. 1475-1487 13 p., 6781587.

Research output: Contribution to journalArticle

27 Scopus citations
2017

The Vascular Impairment of Cognition Classification Consensus Study

VICCCS group, Jun 2017, In : Alzheimer's and Dementia. 13, 6, p. 624-633 10 p.

Research output: Contribution to journalArticle

36 Scopus citations
2011

Music Cognition in Breast Cancer Survivors

Burns, D. S., Bergeson, T. R., Perkins, S. M., Mcdonald, B. C., Saykin, A. J., Unverzagt, F. W. & Champion, V. L., Oct 2011, In : Music & Medicine. 3, 4, p. 258-263 6 p.

Research output: Contribution to journalArticle

2 Scopus citations
2014

Joint identification of imaging and proteomics biomarkers of alzheimer's disease using network-guided sparse learning

Yan, J., Huang, H., Kim, S., Moore, J., Saykin, A. & Shen, L., Jul 29 2014, 2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014. Institute of Electrical and Electronics Engineers Inc., p. 665-668 4 p. 6867958. (2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations
2015

APOE genotype and neuroimaging markers of Alzheimer's disease: Systematic review and meta-analysis

Liu, Y., Yu, J. T., Wang, H. F., Han, P. R., Tan, C. C., Wang, C., Meng, X. F., Risacher, S. L., Saykin, A. J. & Tan, L., Feb 1 2015, In : Journal of Neurology, Neurosurgery and Psychiatry. 86, 2, p. 127-134 8 p.

Research output: Contribution to journalArticle

65 Scopus citations
2016

Quantitative Amyloid imaging in autosomal Dominant Alzheimer's disease: Results from the DIAN study group

Su, Y., Blazey, T. M., Owen, C. J., Christensen, J. J., Friedrichsen, K., Joseph-Mathurin, N., Wang, Q., Hornbeck, R. C., Ances, B. M., Snyder, A. Z., Cash, L. A., Koeppe, R. A., Klunk, W. E., Galasko, D., Brickman, A. M., McDade, E., Ringman, J. M., Thompson, P. M., Saykin, A. J., Ghetti, B. & 16 others, Sperling, R. A., Johnson, K. A., Salloway, S. P., Schofield, P. R., Masters, C. L., Villemagne, V. L., Fox, N. C., Förster, S., Chen, K., Reiman, E. M., Xiong, C., Marcus, D. S., Weiner, M. W., Morris, J. C., Bateman, R. J. & Benzinger, T. L. S., Mar 2016, In : PloS one. 11, 3, e0152082.

Research output: Contribution to journalArticle

24 Scopus citations
2012

Characteristics and variability of structural networks derived from diffusion tensor imaging

Cheng, H., Wang, Y., Sheng, J., Kronenberger, W. G., Mathews, V. P., Hummer, T. A. & Saykin, A. J., Jul 16 2012, In : NeuroImage. 61, 4, p. 1153-1164 12 p.

Research output: Contribution to journalArticle

82 Scopus citations
2015

Brain Health: The Importance of Recognizing Cognitive Impairment: An IAGG Consensus Conference

Morley, J. E., Morris, J. C., Berg-Weger, M., Borson, S., Carpenter, B. D., del Campo, N., Dubois, B., Fargo, K., Fitten, L. J., Flaherty, J. H., Ganguli, M., Grossberg, G. T., Malmstrom, T. K., Petersen, R. D., Rodriguez, C., Saykin, A. J., Scheltens, P., Tangalos, E. G., Verghese, J., Wilcock, G. & 3 others, Winblad, B., Woo, J. & Vellas, B., Sep 1 2015, In : Journal of the American Medical Directors Association. 16, 9, p. 731-739 9 p.

Research output: Contribution to journalArticle

121 Scopus citations

Relationship between the Montreal Cognitive Assessment and Mini-mental State Examination for assessment of mild cognitive impairment in older adults

Trzepacz, P. T., Hochstetler, H., Wang, S., Walker, B. & Saykin, A. J., Sep 7 2015, In : BMC Geriatrics. 15, 1, 107.

Research output: Contribution to journalArticle

160 Scopus citations
2014

Data synthesis and method evaluation for brain imaging genetics

Sheng, J., Kim, S., Yan, J., Moore, J., Saykin, A. & Shen, L., Jul 29 2014, 2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014. Institute of Electrical and Electronics Engineers Inc., p. 1202-1205 4 p. 6868091. (2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Scopus citations
2019

Intrinsic brain activity changes associated with adjuvant chemotherapy in older women with breast cancer: a pilot longitudinal study

Chen, B. T., Jin, T., Patel, S. K., Ye, N., Ma, H., Wong, C. W., Rockne, R. C., Root, J. C., Saykin, A. J., Ahles, T. A., Holodny, A. I., Prakash, N., Mortimer, J., Waisman, J., Yuan, Y., Li, D., Sedrak, M. S., Vazquez, J., Katheria, V. & Dale, W., Jul 15 2019, In : Breast Cancer Research and Treatment. 176, 1, p. 181-189 9 p.

Research output: Contribution to journalArticle

4 Scopus citations
2017

Mapping longitudinal scientific progress, collaboration and impact of the Alzheimer’s disease neuroimaging initiative

Alzheimer’s Disease Neuroimaging Initiative, Nov 2017, In : PloS one. 12, 11, e0186095.

Research output: Contribution to journalArticle

5 Scopus citations
2020

The characterisation of subjective cognitive decline

Jessen, F., Amariglio, R. E., Buckley, R. F., van der Flier, W. M., Han, Y., Molinuevo, J. L., Rabin, L., Rentz, D. M., Rodriguez-Gomez, O., Saykin, A. J., Sikkes, S. A. M., Smart, C. M., Wolfsgruber, S. & Wagner, M., Mar 2020, In : The Lancet Neurology. 19, 3, p. 271-278 8 p.

Research output: Contribution to journalReview article

13 Scopus citations
2019

Plasma amyloid beta levels are associated with cerebral amyloid and tau deposition

Risacher, S. L., Fandos, N., Romero, J., Sherriff, I., Pesini, P., Saykin, A. J. & Apostolova, L. G., Dec 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 510-519 10 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2020

Neurodegenerative Patterns of Cognitive Clusters of Early-Onset Alzheimer's Disease Subjects: Evidence for Disease Heterogeneity

Phillips, M. L., Stage, E. C., Lane, K. A., Gao, S., Risacher, S. L., Goukasian, N., Saykin, A. J., Carrillo, M. C., DIckerson, B. C., Rabinovici, G. D. & Apostolova, L. G., Feb 1 2020, In : Dementia and Geriatric Cognitive Disorders. 48, 3-4, p. 131-142 12 p.

Research output: Contribution to journalArticle

2014

Human connectome module pattern detection using a new multi-graph MinMax cut model

Wang, D., Wang, Y., Nie, F., Yan, J., Cai, W., Saykin, A. J., Shen, L. & Huang, H., Jan 1 2014, Medical Image Computing and Computer-Assisted Intervention, MICCAI 2014 - 17th International Conference, Proceedings. PART 3 ed. Springer Verlag, p. 313-320 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 8675 LNCS, no. PART 3).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Scopus citations
2017

The Impact of Using Different Reference Populations on Measurement of Breast Cancer-Related Cognitive Impairment Rates

Thinking and Living with Cancer (TLC) Study, Nov 24 2017, In : Archives of Clinical Neuropsychology. 33, 8, p. 956-963 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Network approaches to systems biology analysis of complex disease: Integrative methods for multi-omics data

Yan, J., Risacher, S. L., Shen, L. & Saykin, A. J., May 30 2017, In : Briefings in Bioinformatics. 19, 6, p. 1370-1381 12 p.

Research output: Contribution to journalArticle

44 Scopus citations
2013
42 Scopus citations
2016

Structured sparse CCA for brain imaging genetics via graph OSCAR

Du, L., Huang, H., Yan, J., Kim, S., Risacher, S., Inlow, M., Moore, J., Saykin, A. & Shen, L., Aug 26 2016, In : BMC Systems Biology. 10, 68.

Research output: Contribution to journalArticle

7 Scopus citations
2018

Predicting progressions of cognitive outcomes via high-order multi-modal multi-task feature learning

Lu, L., Wang, H., Yao, X., Risacher, S., Saykin, A. & Shen, L., May 23 2018, 2018 IEEE 15th International Symposium on Biomedical Imaging, ISBI 2018. IEEE Computer Society, Vol. 2018-April. p. 545-548 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations
2014

Association of cancer history with alzheimer's disease onset and structural brain changes

Alzheimer's Disease Neuroimaging Initiative, Jan 1 2014, In : Frontiers in Physiology. 5, OCT, Article 423.

Research output: Contribution to journalArticle

25 Scopus citations
2016

Variants in ACPP are associated with cerebrospinal fluid Prostatic Acid Phosphatase levels

for the Alzheimer's Disease Neuroimaging Initiative, Jun 29 2016, In : BMC genomics. 17, 439.

Research output: Contribution to journalArticle

1 Scopus citations
2017

A fast SCCA algorithm for big data analysis in brain imaging genetics

Alzheimer’s Disease Neuroimaging Initiative, 2017, Graphs in Biomedical Image Analysis, Computational Anatomy and Imaging Genetics - 1st International Workshop, GRAIL 2017 6th International Workshop, MFCA 2017 and 3rd International Workshop, MICGen 2017 Held in Conjunction with MICCAI 2017, Proceedings. Springer Verlag, Vol. 10551 LNCS. p. 210-219 10 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10551 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Unified representation of tractography and diffusion-weighted MRI data using sparse multidimensional arrays

Caiafa, C. F., Sporns, O., Saykin, A. & Pestilli, F., Jan 1 2017, In : Advances in Neural Information Processing Systems. 2017-December, p. 4341-4352 12 p.

Research output: Contribution to journalConference article

4 Scopus citations
2011

Genome-wide association reveals dopamine-related genetic effects on caudate volume

Stein, J. L., Hibar, D. P., Madsen, S. K., Khamis, M., McMahon, K. L., De Zubicaray, G. I., Hansell, N. K., Montgomery, G. W., Martin, N. G., Wright, M. J., Saykin, A., Jack, C. R., Weiner, M. W., Toga, A. W. & Thompson, P. M., 2011, In : Molecular Psychiatry. 16, 9, p. 881 1 p.

Research output: Contribution to journalArticle

4 Scopus citations
2012

A large scale multivariate parallel ICA method reveals novel imaging-genetic relationships for Alzheimer's disease in the ADNI cohort

Meda, S. A., Narayanan, B., Liu, J., Perrone-Bizzozero, N. I., Stevens, M. C., Calhoun, V. D., Glahn, D. C., Shen, L., Risacher, S. L., Saykin, A. J. & Pearlson, G. D., Apr 15 2012, In : NeuroImage. 60, 3, p. 1608-1621 14 p.

Research output: Contribution to journalArticle

79 Scopus citations
2011

Sparse multi-task regression and feature selection to identify brain imaging predictors for memory performance

Wang, H., Nie, F., Huang, H., Risacher, S., Ding, C., Saykin, A. J. & Shen, L., Dec 1 2011, 2011 International Conference on Computer Vision, ICCV 2011. p. 557-562 6 p. 6126288. (Proceedings of the IEEE International Conference on Computer Vision).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

88 Scopus citations
2019

Understanding disease progression and improving Alzheimer's disease clinical trials: Recent highlights from the Alzheimer's Disease Neuroimaging Initiative

Alzheimer's Disease Neuroimaging Initiative, Jan 2019, In : Alzheimer's and Dementia. 15, 1, p. 106-152 47 p.

Research output: Contribution to journalReview article

39 Scopus citations

Associations between Depression, Traumatic Brain Injury, and Cognitively-Defined Late-Onset Alzheimer's Disease Subgroups

the Executive Prominent AD (EPAD) investigators, Jan 1 2019, In : Journal of Alzheimer's Disease. 70, 2, p. 609-617 9 p.

Research output: Contribution to journalArticle

2 Scopus citations
2012

Commonfolate gene variant, MTHFR C677T, is associated with brain structure in two independent cohorts of people with mild cognitive impairment

Rajagopalan, P., Jahanshad, N., Stein, J. L., Hua, X., Madsen, S. K., Kohannim, O., Hibar, D. P., Toga, A. W., Jack, C. R., Saykin, A., Green, R. C., Weiner, M. W., Bis, J. C., Kuller, L. H., Riverol, M., Becker, J. T., Lopez, O. L. & Thompson, P. M., 2012, In : NeuroImage: Clinical. 1, 1, p. 179-187 9 p.

Research output: Contribution to journalArticle

24 Scopus citations