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Author

  • Jeffrey Kline
2018

Effect of an educational intervention on medical student scripting and patient satisfaction: A randomized trial

Pettit, K. E., Turner, J. S., Pollard, K. A., Buente, B. B., Humbert, A. J., Perkins, A. J., Hobgood, C. D. & Kline, J. A., May 2018, In : Western Journal of Emergency Medicine. 19, 3, p. 585-592 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
2016

Medical student use of communication elements and association with patient satisfaction: A prospective observational pilot study

Turner, J. S., Pettit, K. E., Buente, B. B., Humbert, A. J., Perkins, A. J. & Kline, J. A., May 21 2016, In : BMC medical education. 16, 1, 150.

Research output: Contribution to journalArticle

4 Scopus citations

Early alterations in platelet mitochondrial function are associated with survival and organ failure in patients with septic shock

Puskarich, M. A., Kline, J. A., Watts, J. A., Shirey, K., Hosler, J. & Jones, A. E., Feb 1 2016, In : Journal of Critical Care. 31, 1, p. 63-67 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

Lactate Clearance in Septic Shock is Not a Surrogate for Improved Microcirculatory Flow

Puskarich, M. A., Shapiro, N. I., Massey, M. J., Kline, J. A., Jones, A. E. & Alpern, E., Jun 1 2016, In : Academic Emergency Medicine. 23, 6, p. 690-693 4 p.

Research output: Contribution to journalArticle

11 Scopus citations
2015
4 Scopus citations
2012

In reply

Mitchell, A. M. & Kline, J. A., Jan 1 2012, In : Academic Emergency Medicine. 19, 1, p. 111-112 2 p.

Research output: Contribution to journalLetter

2013

Computed tomography in the emergency department setting

Venkatesh, A., Kline, J. A. & Kabrhel, C., Jan 28 2013, In : JAMA Internal Medicine. 173, 2, 1 p.

Research output: Contribution to journalLetter

2012

More on the PERC rule

Kline, J. A., Jan 1 2012, In : Annals of emergency medicine. 59, 1, p. 84-85 2 p.

Research output: Contribution to journalLetter

83 Scopus citations
2013

A soluble guanylate cyclase stimulator, BAY 41-8543, preserves right ventricular function in experimental pulmonary embolism

Watts, J. A., Gellar, M. A., Fulkerson, M. B. K. & Kline, J. A., Apr 1 2013, In : Pulmonary Pharmacology and Therapeutics. 26, 2, p. 205-211 7 p.

Research output: Contribution to journalArticle

6 Scopus citations
2016

Diagnosis and Exclusion of Pulmonary Embolism

Kline, J., 2016, (Accepted/In press) In : Thrombosis Research.

Research output: Contribution to journalArticle

12 Scopus citations
2012

Arginase depletes plasma l-arginine and decreases pulmonary vascular reserve during experimental pulmonary embolism

Watts, J. A., Gellar, M. A., Fulkerson, M. B. K., Das, S. K. & Kline, J. A., Feb 1 2012, In : Pulmonary Pharmacology and Therapeutics. 25, 1, p. 48-54 7 p.

Research output: Contribution to journalArticle

18 Scopus citations
2014

Urinary metabolomic analysis to detect changes after intravenous, non-ionic, low osmolar iodinated radiocontrast for computerized tomographic imaging

Diercks, D. B., Owen, K. P., Tolstikov, V., Sutter, M. E. & Kline, J. A., Mar 1 2014, In : Western Journal of Emergency Medicine. 15, 2, p. 152-157 6 p.

Research output: Contribution to journalArticle

Women's health: Essential curriculum in emergency medicine

Kline, J. & Marco, C. A., Dec 1 2014, In : Academic Emergency Medicine. 21, 12, p. 1318-1319 2 p.

Research output: Contribution to journalComment/debate

2017
6 Scopus citations
38 Scopus citations
2016

Pulmonary Embolism Inpatients Treated With Rivaroxaban Had Shorter Hospital Stays and Lower Costs Compared With Warfarin

Margolis, J. M., Deitelzweig, S., Kline, J., Tran, O., Smith, D. M., Crivera, C., Bookhart, B. & Schein, J., Nov 1 2016, In : Clinical Therapeutics. 38, 11, p. 2496-2503 8 p.

Research output: Contribution to journalArticle

5 Scopus citations
2012

Therapy and outcomes in massive pulmonary embolism from the Emergency Medicine Pulmonary Embolism in the Real World Registry

Lin, B. W., Schreiber, D. H., Liu, G., Briese, B., Hiestand, B., Slattery, D., Kline, J. A., Goldhaber, S. Z. & Pollack, C. V., Nov 1 2012, In : American Journal of Emergency Medicine. 30, 9, p. 1774-1781 8 p.

Research output: Contribution to journalArticle

36 Scopus citations
2016

Research Priorities in Submassive Pulmonary Embolism: Proceedings from a Multidisciplinary Research Consensus Panel

Sista, A. K., Goldhaber, S. Z., Vedantham, S., Kline, J., Kuo, W. T., Kahn, S. R., Kabrhel, C., McLaughlin, V. V., White, S. B., Kim, N. H., Gray, M., Simon, M. A., Benenati, J. F., Misra, S., Sterling, K. M., Kee, S. T., Konstantinides, S. V., Jaff, M. R. & Kearon, C., Jun 1 2016, In : Journal of Vascular and Interventional Radiology. 27, 6, p. 787-794 8 p.

Research output: Contribution to journalReview article

17 Scopus citations
2012

Risk stratification and treatment strategy of pulmonary embolism

Penaloza, A., Roy, P. M. & Kline, J., Aug 1 2012, In : Current Opinion in Critical Care. 18, 4, p. 318-325 8 p.

Research output: Contribution to journalReview article

19 Scopus citations
2011

Cost-effectiveness of an emergency department-based early sepsis resuscitation protocol

Jones, A. E., Troyer, J. L. & Kline, J. A., Jun 2011, In : Critical care medicine. 39, 6, p. 1306-1312 7 p.

Research output: Contribution to journalArticle

38 Scopus citations
2018

Emergency Department Discharge of Pulmonary Embolus Patients

Frank Peacock, W., Coleman, C. I., Diercks, D. B., Francis, S., Kabrhel, C., Keay, C., Kline, J. A., Manteuffel, J., Wildgoose, P., Xiang, J. & Singer, A. J., Sep 2018, In : Academic Emergency Medicine. 25, 9, p. 995-1003 9 p.

Research output: Contribution to journalArticle

9 Scopus citations
2019

The conference effect: National surgery meetings are associated with increased mortality at trauma centers without American College of Surgeons verification

Jenkins, P. C., Painter, S., Bell, T. M., Kline, J. A. & Zarzaur, B. L., Mar 2019, In : PloS one. 14, 3, e0214020.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

Assessment of right ventricular function in the research setting: Knowledge gaps and pathways forward an official American thoracic society research statement

Lahm, T., Douglas, I. S., Archer, S. L., Bogaard, H. J., Chesler, N. C., Haddad, F., Hemnes, A. R., Kawut, S. M., Kline, J. A., Kolb, T. M., Mathai, S. C., Mercier, O., Michelakis, E. D., Naeije, R., Tuder, R. M., Ventetuolo, C. E., Vieillard-Baron, A., Voelkel, N. F., Vonk-Noordegraaf, A. & Hassoun, P. M., Aug 15 2018, In : American Journal of Respiratory and Critical Care Medicine. 198, 4, p. e15-e43

Research output: Contribution to journalReview article

38 Scopus citations
2017

High-intensity interval training, but not continuous training, reverses right ventricular hypertrophy and dysfunction in a rat model of pulmonary hypertension

Brown, M. B., Neves, E., Long, G., Graber, J., Gladish, B., Wiseman, A., Owens, M., Fisher, A. J., Presson, R. G., Petrache, I., Kline, J. & Lahm, T., 2017, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 312, 2, p. R197-R210

Research output: Contribution to journalArticle

20 Scopus citations
2011

Up-regulation of arginase II contributes to pulmonary vascular endothelial cell dysfunction during experimental pulmonary embolism

Watts, J. A., Marchick, M. R., Gellar, M. A. & Kline, J. A., Aug 1 2011, In : Pulmonary Pharmacology and Therapeutics. 24, 4, p. 407-413 7 p.

Research output: Contribution to journalArticle

13 Scopus citations
2014

Identification of reduced circulating haptoglobin concentration as a biomarker of the severity of pulmonary embolism: A nontargeted proteomic study

Insenser, M., Montes-Nieto, R., Martínez-García, M. Á., Durań, E. F., Santiuste, C., Goḿez, V., Kline, J. A., Escobar-Morreale, H. F. & Jimeńez, D., Jun 30 2014, In : PLoS ONE. 9, 6, e100902.

Research output: Contribution to journalArticle

9 Scopus citations
2018

Anxiety Associated With Increased Risk for Emergency Department Recidivism in Patients With Low-Risk Chest Pain

Musey, P. I., Patel, R., Fry, C., Jimenez, G., Koene, R. & Kline, J. A., Oct 1 2018, In : American Journal of Cardiology. 122, 7, p. 1133-1141 9 p.

Research output: Contribution to journalArticle

4 Scopus citations
2011

Association between timing of antibiotic administration and mortality from septic shock in patients treated with a quantitative resuscitation protocol

Puskarich, M. A., Trzeciak, S., Shapiro, N. I., Arnold, R. C., Horton, J. M., Studnek, J. R., Kline, J. A. & Jones, A. E., Sep 2011, In : Critical care medicine. 39, 9, p. 2066-2071 6 p.

Research output: Contribution to journalArticle

223 Scopus citations
2012

Prognostic value and agreement of achieving lactate clearance or central venous oxygen saturation goals during early sepsis resuscitation

Puskarich, M. A., Trzeciak, S., Shapiro, N. I., Arnold, R. C., Heffner, A. C., Kline, J. A. & Jones, A. E., Mar 1 2012, In : Academic Emergency Medicine. 19, 3, p. 252-258 7 p.

Research output: Contribution to journalArticle

72 Scopus citations
2013

Whole blood lactate kinetics in patients undergoing quantitative resuscitation for severe sepsis and septic shock

Puskarich, M. A., Trzeciak, S., Shapiro, N. I., Albers, A. B., Heffner, A. C., Kline, J. A. & Jones, A. E., Jun 2013, In : Chest. 143, 6, p. 1548-1553 6 p.

Research output: Contribution to journalArticle

78 Scopus citations
2014

Multicenter, randomized trial of quantitative pretest probability to reduce unnecessary medical radiation exposure in emergency department patients with chest pain and dyspnea

Kline, J. A., Jones, A. E., Shapiro, N. I., Hernandez, J., Hogg, M. M., Troyer, J. & Nelson, R. D., Jan 2014, In : Circulation: Cardiovascular Imaging. 7, 1, p. 66-73 8 p.

Research output: Contribution to journalArticle

28 Scopus citations
2012

Normalization of vital signs does not reduce the probability of acute pulmonary embolism in symptomatic emergency department patients

Kline, J. A., Corredor, D. M., Hogg, M. M., Hernandez, J. & Jones, A. E., Jan 1 2012, In : Academic Emergency Medicine. 19, 1, p. 11-17 7 p.

Research output: Contribution to journalArticle

11 Scopus citations
2014

Association of body mass index with increased cost of care and length of stay for emergency department patients with chest pain and dyspnea

Peitz, G. W., Troyer, J., Jones, A. E., Shapiro, N. I., Nelson, R. D., Hernandez, J. & Kline, J. A., Mar 2014, In : Circulation: Cardiovascular Quality and Outcomes. 7, 2, p. 292-298 7 p.

Research output: Contribution to journalArticle

13 Scopus citations
2019

Association Between Elevated Mean Arterial Blood Pressure and Neurologic Outcome After Resuscitation From Cardiac Arrest: Results From a Multicenter Prospective Cohort Study

Roberts, B. W., Kilgannon, J. H., Hunter, B. R., Puskarich, M. A., Shea, L., Donnino, M., Jones, C., Fuller, B. M., Kline, J. A., Jones, A. E., Shapiro, N. I., Abella, B. S. & Trzeciak, S., Jan 1 2019, In : Critical care medicine. 47, 1, p. 93-100 8 p.

Research output: Contribution to journalArticle

14 Scopus citations
2012

2-Hour accelerated diagnostic protocol to assess patients with chest pain symptoms using contemporary troponins as the only biomarker: The ADAPT trial

Than, M., Cullen, L., Aldous, S., Parsonage, W. A., Reid, C. M., Greenslade, J., Flaws, D., Hammett, C. J., Beam, D. M., Ardagh, M. W., Troughton, R., Brown, A. F. T., George, P., Florkowski, C. M., Kline, J. A., Peacock, W. F., Maisel, A. S., Lim, S. H., Lamanna, A. & Richards, A. M., Jun 5 2012, In : Journal of the American College of Cardiology. 59, 23, p. 2091-2098 8 p.

Research output: Contribution to journalArticle

273 Scopus citations
2016

Shared decision making in patients with low risk chest pain: Prospective randomized pragmatic trial

Hess, E. P., Hollander, J. E., Schaffer, J. T., Kline, J. A., Torres, C. A., Diercks, D. B., Jones, R., Owen, K. P., Meisel, Z. F., Demers, M., LeBlanc, A., Shah, N. D., Inselman, J., Herrin, J., Castaneda-Guarderas, A. & Montori, V. M., 2016, In : BMJ (Online). 355, hese034721.

Research output: Contribution to journalArticle

61 Scopus citations
2012

The chest pain choice decision aid: A randomized trial

Hess, E. P., Knoedler, M. A., Shah, N. D., Kline, J. A., Breslin, M., Branda, M. E., Pencille, L. J., Asplin, B. R., Nestler, D. M., Sadosty, A. T., Stiell, I. G., Ting, H. H. & Montori, V. M., May 1 2012, In : Circulation: Cardiovascular Quality and Outcomes. 5, 3, p. 251-259 9 p.

Research output: Contribution to journalArticle

165 Scopus citations
2015

Findings from 12-lead electrocardiography that predict circulatory shock from pulmonary embolism: Systematic review and meta-analysis

Shopp, J. D., Stewart, L. K., Emmett, T. W. & Kline, J. A., Oct 2015, In : Academic Emergency Medicine. 22, 10, p. 1127-1137 11 p.

Research output: Contribution to journalArticle

28 Scopus citations
2016

Variable resistance to plasminogen activator initiated fibrinolysis for intermediate-risk pulmonary embolism

Stubblefield, W. B., Alves, N. J., Rondina, M. T. & Kline, J. A., Feb 2016, In : PloS one. 11, 2, e0148747.

Research output: Contribution to journalArticle

7 Scopus citations
2014

Urinary metabolomic analysis to detect changes after intravenous, non-ionic, low osmolar iodinated radiocontrast for computerized tomographic imaging

Diercks, D. B., Owen, K. P., Tolstikov, V., Sutter, M. E. & Kline, J. A., 2014, In : Western Journal of Emergency Medicine. 15, 2, p. 152-157 6 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2011

Clinical characteristics, management, and outcomes of patients diagnosed with acute pulmonary embolism in the emergency department: Initial report of EMPEROR (multicenter emergency medicine pulmonary embolism in the real world registry)

Pollack, C. V., Schreiber, D., Goldhaber, S. Z., Slattery, D., Fanikos, J., O'Neil, B. J., Thompson, J. R., Hiestand, B., Briese, B. A., Pendleton, R. C., Miller, C. D. & Kline, J. A., Feb 8 2011, In : Journal of the American College of Cardiology. 57, 6, p. 700-706 7 p.

Research output: Contribution to journalArticle

257 Scopus citations
2017

Chronic Embolic Pulmonary Hypertension Caused by Pulmonary Embolism and Vascular Endothelial Growth Factor Inhibition

Neto-Neves, E. M., Brown, M. B., Zaretskaia, M. V., Rezania, S., Goodwill, A. G., McCarthy, B. P., Persohn, S. A., Territo, P. R. & Kline, J. A., Apr 1 2017, In : American Journal of Pathology. 187, 4, p. 700-712 13 p.

Research output: Contribution to journalArticle

7 Scopus citations
2013

What is an acceptable risk of major adverse cardiac event in chest pain patients soon after discharge from the Emergency Department? A clinical survey

Than, M., Herbert, M., Flaws, D., Cullen, L., Hess, E., Hollander, J. E., Diercks, D., Ardagh, M. W., Kline, J. A., Munro, Z. & Jaffe, A., Jul 1 2013, In : International Journal of Cardiology. 166, 3, p. 752-754 3 p.

Research output: Contribution to journalArticle

198 Scopus citations
2014

Development and validation of the emergency department assessment of chest pain score and 2h accelerated diagnostic protocol

Than, M., Flaws, D., Sanders, S., Doust, J., Glasziou, P., Kline, J., Aldous, S., Troughton, R., Reid, C., Parsonage, W. A., Frampton, C., Greenslade, J. H., Deely, J. M., Hess, E., Sadiq, A. B., Singleton, R., Shopland, R., Vercoe, L., Woolhouse-Williams, M., Ardagh, M. & 3 others, Bossuyt, P., Bannister, L. & Cullen, L., Feb 1 2014, In : EMA - Emergency Medicine Australasia. 26, 1, p. 34-44 11 p.

Research output: Contribution to journalArticle

93 Scopus citations
2015

Independent evaluation of a simple clinical prediction rule to identify right ventricular dysfunction in patients with shortness of breath

Russell, F. M., Moore, C. L., Courtney, D. M., Kabrhel, C., Smithline, H. A., Nordenholz, K. E., Richman, P. B., O'Neil, B. J., Plewa, M. C., Beam, D. M., Mastouri, R. & Kline, J. A., Apr 1 2015, In : American Journal of Emergency Medicine. 33, 4, p. 542-547 6 p.

Research output: Contribution to journalArticle

6 Scopus citations
2013

Rationale and methodology for a multicentre randomised trial of fibrinolysis for pulmonary embolism that includes quality of life outcomes

Kline, J. A., Hernandez, J., Hogg, M. M., Jones, A. E., Courtney, D. M., Kabrhel, C., Nordenholz, K. E., Diercks, D. B., Rondina, M. T. & Klinger, J. R., Dec 1 2013, In : EMA - Emergency Medicine Australasia. 25, 6, p. 515-526 12 p.

Research output: Contribution to journalArticle

10 Scopus citations
2014

Severe pulmonary embolism decreases plasma L-arginine

Kline, J. A., Watts, J., Courtney, D., Lee, Y. Y. & Hwang, S., Mar 1 2014, In : European Respiratory Journal. 43, 3, p. 906-909 4 p.

Research output: Contribution to journalLetter

7 Scopus citations
2018

Validation of the STA-Liatest DDi assay for exclusion of proximal deep vein thrombosis according to the latest Clinical and Laboratory Standards Institute/Food and Drug Administration guideline: Results of a multicenter management study

Aguilar, C., Sartori, M., D'Angelo, A., Kabrhel, C., Groce, J., De Maistre, E., Wasan, S. M., Kassis, J., Lazarchick, J., Kaide, C., Vera, P. M., Kline, J., Courtney, D. M., Rubin, A., Sharafuddin, M. & Pernod, G., 2018, In : Blood Coagulation and Fibrinolysis. 29, 6, p. 562-566 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Ruling out pulmonary embolism in patients with high pretest probability

Akhter, M., Kline, J., Bhattarai, B., Courtney, M. & Kabrhel, C., May 2018, In : Western Journal of Emergency Medicine. 19, 3, p. 487-493 7 p.

Research output: Contribution to journalArticle