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  • Liang Cheng
2017

Prostate cancer biomarkers: Current status

Hodges, K. B., Bachert, E. & Cheng, L., Jan 1 2017, In : Critical Reviews in Oncogenesis. 22, 5-6, p. 353-369 17 p.

Research output: Contribution to journalReview article

2 Scopus citations
2018

Biological issues with cabozantinib in bone metastatic renal cell carcinoma and castration-resistant prostate cancer

Di Nunno, V., Cimadamore, A., Santoni, M., Scarpelli, M., Fiorentino, M., Ciccarese, C., Iacovelli, R., Cheng, L., Lopez-Beltran, A., Massari, F. & Montironi, R., Oct 2018, In : Future Oncology. 14, 25, p. 2559-2564 6 p.

Research output: Contribution to journalComment/debate

3 Scopus citations

Classical gonadoblastoma: its relationship to the ‘dissecting’ variant and undifferentiated gonadal tissue

Roth, L. M. & Cheng, L., Mar 2018, In : Histopathology. 72, 4, p. 545-555 11 p.

Research output: Contribution to journalReview article

8 Scopus citations
2016

Renal pelvis, ureter, and urethra

Lopez-Beltran, A., Williamson, S. R. & Cheng, L., Feb 13 2016, Essentials of Anatomic Pathology: Fourth Edition. Springer International Publishing, p. 1737-1750 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2017

Design and in-vivo evaluation of next-generation laparoscopic HIFU kidney probe

Seip, R., Morris, A., Chaluisan, R., Clanton, J., Carlson, R., Carr, J., Johnson, C., Sanghvi, N., Smith, J., Matam, M., Morris, J., Chopra, S., Gill, I., Shum, C. F., Sundaram, C., Cheng, L. & Carol, M., Oct 31 2017, 2017 IEEE International Ultrasonics Symposium, IUS 2017. IEEE Computer Society, 8092872. (IEEE International Ultrasonics Symposium, IUS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2016

Prostate cancer glands with cribriform architecture and with glomeruloid features should be considered as Gleason pattern 4 and not pattern 3

Minardi, D., Mazzucchelli, R., Scarpelli, M., Massari, F., Ciccarese, C., Lopez-Beltran, A., Cheng, L. & Montironi, R., Jun 2016, In : Future Oncology. 12, 12, p. 1431-1433 3 p.

Research output: Contribution to journalReview article

4 Scopus citations
2019

Distinct mutational landscape of inverted urothelial papilloma

Akgul, M., MacLennan, G. T. & Cheng, L., Jan 1 2019, In : Journal of Pathology. 249, 1, p. 3-5 3 p.

Research output: Contribution to journalComment/debate

Open Access
4 Scopus citations
2017

From Gleason Grading System and High-grade Tertiary Patterns to Grade Groups and Integrated Quantitative Gleason Score

Montironi, R., Cheng, L., Scarpelli, M. & Lopez-Beltran, A., 2017, (Accepted/In press) In : European Urology.

Research output: Contribution to journalArticle

2 Scopus citations
2019

Expression of miR-100 and miR-138 as prognostic biomarkers in non-muscle-invasive bladder cancer

Blanca, A., Sanchez-Gonzalez, A., Requena, M. J., Carrasco-Valiente, J., Gomez-Gomez, E., Cheng, L., Cimadamore, A., Montironi, R. & Lopez-Beltran, A., Aug 2019, In : APMIS. 127, 8, p. 545-553 9 p.

Research output: Contribution to journalArticle

3 Scopus citations
2016

Human papillomavirus (HPV)-induced neoplasia in the urinary bladder: A missing link?

Alexander, R. E., Wang, L., Lopez-Beltran, A., Emerson, R. E., Montironi, R., Pedrosa, J. A., Kaimakliotis, H. Z., Koch, M. O. & Cheng, L., Jun 2016, In : Histology and Histopathology. 31, 6, p. 595-600 6 p.

Research output: Contribution to journalReview article

6 Scopus citations

Synchronous clear cell renal cell carcinoma and multilocular cystic renal cell neoplasia of low malignant potential: A clinico-pathologic and molecular study

Raspollini, M. R., Castiglione, F., Cheng, L., Montironi, R. & Lopez-Beltran, A., May 1 2016, In : Pathology Research and Practice. 212, 5, p. 471-474 4 p.

Research output: Contribution to journalArticle

3 Scopus citations
2018

Physiological stretch induced proliferation of human urothelial cells via integrin α6-FAK signaling pathway

Gao, X., Wei, T., Liao, B., Ai, J., Zhou, L., Gong, L., Chen, Y., He, Q., Cheng, L. & Wang, K., Sep 2018, In : Neurourology and Urodynamics. 37, 7, p. 2114-2120 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2017

TMPRSS2-ERG gene fusion is rare compared to PTEN deletions in stage T1a prostate cancer

Fisher, K. W., Zhang, S., Wang, M., Montironi, R., Wang, L., Baldrige, L. A., Wang, J. Y., MacLennan, G. T., Williamson, S. R., Lopez-Beltran, A. & Cheng, L., Mar 1 2017, In : Molecular Carcinogenesis. 56, 3, p. 814-820 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Epigenetic modifications and modulators in prostate cancer

Cimadamore, A., Gasparrini, S., Scarpelli, M., Doria, A., Mazzucchelli, R., Massari, F., Cheng, L., Lopez-Beltran, A. & Montironi, R., Jan 1 2017, In : Critical Reviews in Oncogenesis. 22, 5-6, p. 439-450 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Activity and Functions of Tumor-associated Macrophages in Prostate Carcinogenesis

Santoni, M., Cheng, L., Conti, A., Mariani, C., Lopez-Beltran, A., Montironi, R. & Battelli, N., Dec 2017, In : European Urology, Supplements. 16, 12, p. 301-308 8 p.

Research output: Contribution to journalReview article

4 Scopus citations

Immunotherapy in genitourinary cancers: Where are we going?

Bianconi, M., Faloppi, L., Lopez-Beltran, A., Cheng, L., Cimadamore, A., Gasparrini, S., Massari, F., Scarpelli, M. & Montironi, R., Jan 1 2017, In : Expert Review of Precision Medicine and Drug Development. 2, 2, p. 73-78 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2016

Use of the cell cycle progression (CCP) score for predicting systemic disease and response to radiation of biochemical recurrence

Koch, M., Cho, J. S., Kaimakliotis, H., Cheng, L., Sangale, Z., Brawer, M., Welbourn, W., Reid, J. & Stone, S., 2016, In : Cancer Biomarkers. 17, 1, p. 83-88 6 p.

Research output: Contribution to journalArticle

8 Scopus citations
2017
2016

Telomerase reverse transcriptase (TERT) promoter mutation analysis of benign, malignant and reactive urothelial lesions reveals a subpopulation of inverted papilloma with immortalizing genetic change

Cheng, L., Davidson, D. D., Wang, M., Lopez-Beltran, A., Montironi, R., Wang, L., Tan, P. H., MacLennan, G. T., Williamson, S. R. & Zhang, S., Jul 1 2016, In : Histopathology. 69, 1, p. 107-113 7 p.

Research output: Contribution to journalArticle

21 Scopus citations
2017

TMPRSS2-ERG Fusion in an Uncommon Presentation of Prostate Cancer

Adra, N., Cheng, L., Hanna, N. H. & Durm, G., Jun 2017, In : Clinical Genitourinary Cancer. 15, 3, p. e489-e491

Research output: Contribution to journalArticle

2018

Unclassified hemangioma-like renal cell carcinoma: a potential diagnostic pitfall

Taneja, K., Arora, S., Rogers, C. G., Gupta, N. S., Cheng, L. & Williamson, S. R., May 2018, In : Human pathology. 75, p. 132-136 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Multidisciplinary clinic approach improves overall survival outcomes of patients with metastatic germ-cell tumors

Albany, C., Adra, N., Snavely, A. C., Cary, C., Masterson, T. A., Foster, R. S., Kesler, K., Ulbright, T. M., Cheng, L., Chovanec, M., Taza, F., Ku, K., Brames, M. J., Hanna, N. H. & Einhorn, L. H., Feb 1 2018, In : Annals of Oncology. 29, 2, p. 341-346 6 p.

Research output: Contribution to journalArticle

33 Scopus citations

Vasitis nodosa and related lesions: a modern immunohistochemical staining profile with special emphasis on novel diagnostic dilemmas

Kezlarian, B. E., Cheng, L., Gupta, N. S. & Williamson, S. R., Mar 1 2018, In : Human Pathology. 73, p. 164-170 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Quick steps toward precision medicine in renal cell carcinoma

Massari, F., Santoni, M., Di Nunno, V., Cimadamore, A., Battelli, N., Scarpelli, M., Cheng, M., Lopez-Beltran, A., Cheng, L. & Montironi, R., Jan 1 2018, (Accepted/In press) In : Expert Review of Precision Medicine and Drug Development.

Research output: Contribution to journalArticle

2017

Predicting the biological behavior of non-muscle-invasive bladder cancer: From histology to molecular taxonomy

Luchini, C. & Cheng, L., Oct 1 2017, In : Translational Andrology and Urology. 6, 5, p. 987-990 4 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Complexity of the genomic landscape of renal cell carcinoma: Implications for targeted therapy and precision immuno-oncology

Sanfrancesco, J. M. & Cheng, L., Nov 1 2017, In : Critical Reviews in Oncology/Hematology. 119, p. 23-28 6 p.

Research output: Contribution to journalReview article

11 Scopus citations
2018

Prostate Cancer Grading: Are We Heading Towards Grade Grouping Version 2?

Montironi, R., Cheng, L., Cimadamore, A. & Lopez-Beltran, A., Jan 1 2018, (Accepted/In press) In : European Urology.

Research output: Contribution to journalArticle

1 Scopus citations

Re: Novel Tool for Predicting Extracapsular Extension During Graded Partial Nerve Sparing in Radical Prostatectomy

Montironi, R., Cheng, L., Lopez-Beltran, A., Scarpelli, M. & Montorsi, F., Jan 1 2018, (Accepted/In press) In : European Urology.

Research output: Contribution to journalArticle

2016

FGFR3 and Cyclin D3 as urine biomarkers of bladder cancer recurrence

Blanca, A., Requena, M. J., Alvarez, J., Cheng, L., Montironi, R., Raspollini, M. R., Reymundo, C. & Lopez-Beltran, A., Mar 1 2016, In : Biomarkers in Medicine. 10, 3, p. 243-253 11 p.

Research output: Contribution to journalArticle

10 Scopus citations
2018

Prostate cancer with cribriform morphology: diagnosis, aggressiveness, molecular pathology and possible relationships with intraductal carcinoma

Montironi, R., Cimadamore, A., Gasparrini, S., Mazzucchelli, R., Santoni, M., Massari, F., Cheng, L., Lopez-Beltran, A. & Scarpelli, M., Jul 3 2018, In : Expert Review of Anticancer Therapy. 18, 7, p. 685-693 9 p.

Research output: Contribution to journalReview article

5 Scopus citations
2017

A contemporary series of renal masses with emphasis on recently recognized entities and tumors of low malignant potential: A report based on 624 consecutive tumors from a single tertiary center

Raspollini, M. R., Montagnani, I., Montironi, R., Cheng, L., Martignoni, G., Minervini, A., Serni, S., Nicita, G., Carini, M. & Lopez-Beltran, A., Jul 2017, In : Pathology Research and Practice. 213, 7, p. 804-808 5 p.

Research output: Contribution to journalArticle

2 Scopus citations
2019

Renal cell carcinoma staging: pitfalls, challenges, and updates

Williamson, S. R., Taneja, K. & Cheng, L., Jan 2019, In : Histopathology. 74, 1, p. 18-30 13 p.

Research output: Contribution to journalReview article

18 Scopus citations
2016

Handling of the surgical specimen and pathology reporting of malignant germ cell and sex cord-stromal tumors of the testis

Scarpelli, M., Mazzucchelli, R., Santoni, M., Sotte, V., Conti, A., Lopez-Beltran, A., Cheng, L. & Montironi, R., May 2 2016, Pathology of Testicular and Penile Neoplasms. Springer International Publishing, p. 165-170 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2019

Circulating tumor cells in renal cell carcinoma: Recent findings and future challenges

Santoni, M., Cimadamore, A., Cheng, L., Lopez-Beltran, A., Battelli, N., Massari, F., Scarpelli, M., Galosi, A. B., Bracarda, S. & Montironi, R., 2019, In : Frontiers in Oncology. 9, APR, 228.

Research output: Contribution to journalComment/debate

Open Access
7 Scopus citations
2018

Next-Generation Sequencing to Detect Deletion of RB1 and ERBB4 Genes in Chromophobe Renal Cell Carcinoma: A Potential Role in Distinguishing Chromophobe Renal Cell Carcinoma from Renal Oncocytoma

Liu, Q., Cornejo, K. M., Cheng, L., Hutchinson, L., Wang, M., Zhang, S., Tomaszewicz, K., Cosar, E. F., Woda, B. A. & Jiang, Z., Apr 2018, In : American Journal of Pathology. 188, 4, p. 846-852 7 p.

Research output: Contribution to journalArticle

7 Scopus citations
2019

Contemporary best practice in the management of urothelial carcinomas of the renal pelvis and ureter

Bianconi, M., Cimadamore, A., Faloppi, L., Scartozzi, M., Santoni, M., Lopez-Beltran, A., Cheng, L., Scarpelli, M. & Montironi, R., Jan 1 2019, In : Therapeutic Advances in Urology. 11

Research output: Contribution to journalReview article

4 Scopus citations
2016

Testing PD-1/PD-L1 expression in cancer therapy: Pathologic insights and economic sustainability

Montironi, R., Santoni, M., Tartari, F., Lopez-Beltran, A., Cheng, L., Berardi, R. & Scarpelli, M., Jun 1 2016, In : Archives of Pathology and Laboratory Medicine. 140, 6, p. 501-502 2 p.

Research output: Contribution to journalLetter

8 Scopus citations

Atypical renal cysts a morphologic, immunohistochemical, and molecular study

Matoso, A., Chen, Y. B., Rao, V., Wang, L., Cheng, L. & Epstein, J. I., Jan 1 2016, In : American Journal of Surgical Pathology. 40, 2, p. 202-211 10 p.

Research output: Contribution to journalArticle

8 Scopus citations
2019

Perineural Invasion is a Strong Prognostic Moderator in Ampulla of Vater Carcinoma: A Meta-analysis

Luchini, C., Veronese, N., Nottegar, A., Riva, G., Pilati, C., Mafficini, A., Stubbs, B., Simbolo, M., Mombello, A., Corbo, V., Cheng, L., Yachida, S., Wood, L. D., Lawlor, R. T., Salvia, R. & Scarpa, A., Jan 1 2019, In : Pancreas. 48, 1, p. 70-76 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Detection of androgen receptor (AR) and AR-V7 in small cell prostate carcinoma: Diagnostic and therapeutic implications

Zhao, P., Zhu, Y., Cheng, L. & Luo, J., Jan 2019, In : Asian Journal of Urology. 6, 1, p. 109-113 5 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Editorial: Emerging biomarkers in genitourinary tumors

Montironi, R., Santoni, M., Cimadamore, A., Lopez-Beltran, A. & Cheng, L., 2019, In : Frontiers in Oncology. 9, APR, 326.

Research output: Contribution to journalEditorial

Open Access
2 Scopus citations
2017
6 Scopus citations
2016

Chromosome 12p abnormalities and IMP3 expression in prepubertal pure testicular teratomas

Cornejo, K. M., Cheng, L., Church, A., Wang, M. & Jiang, Z., Mar 1 2016, In : Human pathology. 49, p. 54-60 7 p.

Research output: Contribution to journalArticle

12 Scopus citations
2017

Perspectives on testicular germ cell neoplasms

Cheng, L., Lyu, B. & Roth, L. M., Jan 1 2017, In : Human pathology. 59, p. 10-25 16 p.

Research output: Contribution to journalArticle

32 Scopus citations

Protein arginine methyltransferase 5 functions as an epigenetic activator of the androgen receptor to promote prostate cancer cell growth

Deng, X., Shao, G., Zhang, H. T., Li, C., Zhang, D., Cheng, L., Elzey, B. D., Pili, R., Ratliff, T. L., Huang, J. & Hu, C. D., Mar 2 2017, In : Oncogene. 36, 9, p. 1223-1231 9 p.

Research output: Contribution to journalArticle

39 Scopus citations

Rhabdoid and undifferentiated phenotype in renal cell carcinoma: Analysis of 32 cases indicating a distinctive common pathway of dedifferentiation frequently associated with SWI/SNF complex deficiency

Agaimy, A., Cheng, L., Egevad, L., Feyerabend, B., Hes, O., Keck, B., Pizzolitto, S., Sioletic, S., Wullich, B. & Hartmann, A., Jan 1 2017, In : American Journal of Surgical Pathology. 41, 2, p. 253-262 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Tp53 and its potential therapeutic role as a target in bladder cancer

Ciccarese, C., Massari, F., Blanca, A., Tortora, G., Montironi, R., Cheng, L., Scarpelli, M., Raspollini, M. R., Vau, N., Fonseca, J. & Lopez-Beltran, A., Apr 3 2017, In : Expert Opinion on Therapeutic Targets. 21, 4, p. 401-414 14 p.

Research output: Contribution to journalReview article

11 Scopus citations

Use of Precision Medicine Molecular Profiling of Baseline Tumor Specimen May Not Benefit Outcomes in Children With Relapsed or Refractory Pediatric Sarcomas

Carter, J., Cheng, L., Zucker, J., Marshall, M., Pollok, K., Murray, M., Li, L. & Renbarger, J., Mar 1 2017, In : Clinical Pharmacology and Therapeutics. 101, 3, p. 328-330 3 p.

Research output: Contribution to journalArticle

1 Scopus citations