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  • Andrew Saykin
2019

Telomere length associations with cognition depend on Alzheimer's disease biomarkers

Alzheimer's Disease Neuroimaging Initiative, 2019, In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 5, p. 883-890 8 p.

Research output: Contribution to journalArticle

Open Access
2018

Bootstrapped Sparse Canonical Correlation Analysis: Mining Stable Imaging and Genetic Associations With Implicit Structure Learning. Mining Stable Imaging and Genetic Associations With Implicit Structure Learning.

Yan, J., Du, L., Kim, S., Risacher, S. L., Huang, H., Inlow, M., Moore, J. H., Saykin, A. J. & Shen, L., Jan 1 2018, Imaging Genetics. Elsevier Inc., p. 101-117 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

International cognition and cancer task force recommendations for neuroimaging methods in the study of cognitive impairment in non-CNS cancer patients

Deprez, S., Kesler, S. R., Saykin, A. J., Silverman, D. H. S., De Ruiter, M. B. & McDonald, B. C., Mar 1 2018, In : Journal of the National Cancer Institute. 110, 3, p. 223-231 9 p.

Research output: Contribution to journalReview article

17 Scopus citations
2017

Network approaches to systems biology analysis of complex disease: Integrative methods for multi-omics data

Yan, J., Risacher, S. L., Shen, L. & Saykin, A. J., May 30 2017, In : Briefings in Bioinformatics. 19, 6, p. 1370-1381 12 p.

Research output: Contribution to journalArticle

34 Scopus citations
2018

Sex Differences in Cognitive Decline in Subjects with High Likelihood of Mild Cognitive Impairment due to Alzheimer's disease

Sohn, D., Shpanskaya, K., Lucas, J. E., Petrella, J. R., Saykin, A. J., Tanzi, R. E., Samatova, N. F. & Doraiswamy, P. M., Dec 1 2018, In : Scientific reports. 8, 1, 7490.

Research output: Contribution to journalArticle

11 Scopus citations
2019

Cerebral blood flow in acute concussion: preliminary ASL findings from the NCAA-DoD CARE consortium

Wang, Y., Nencka, A. S., Meier, T. B., Guskiewicz, K., Mihalik, J. P., Alison Brooks, M., Saykin, A. J., Koch, K. M., Wu, Y. C., Nelson, L. D., McAllister, T. W., Broglio, S. P. & McCrea, M. A., Oct 1 2019, In : Brain Imaging and Behavior. 13, 5, p. 1375-1385 11 p.

Research output: Contribution to journalArticle

4 Scopus citations
2016

Network-based analysis of genetic variants associated with hippocampal volume in Alzheimer's disease: A study of ADNI cohorts

Song, A., Yan, J., Kim, S., Risacher, S. L., Wong, A. K., Saykin, A. J., Shen, L. & Greene, C. S., Jan 19 2016, In : BioData Mining. 9, 1, 3.

Research output: Contribution to journalArticle

14 Scopus citations
2019

Telomere Shortening in the Alzheimer's Disease Neuroimaging Initiative Cohort

Nudelman, K. N. H., Lin, J., Lane, K. A., Nho, K., Kim, S., Faber, K. M., Risacher, S. L., Foroud, T. M., Gao, S., Davis, J. W., Weiner, M. W. & Saykin, A. J., Jan 1 2019, In : Journal of Alzheimer's Disease. 71, 1, p. 33-43 11 p.

Research output: Contribution to journalArticle

4 Scopus citations
2016

The effect of the top 20 Alzheimer disease risk genes on gray-matter density and FDG PET brain metabolism

Stage, E., Duran, T., Risacher, S. L., Goukasian, N., Do, T. M., West, J. D., Wilhalme, H., Nho, K., Phillips, M., Elashoff, D., Saykin, A. J. & Apostolova, L. G., Jan 1 2016, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 5, p. 53-66 14 p.

Research output: Contribution to journalArticle

12 Scopus citations
2018

Detection of tau in Gerstmann-Sträussler-Scheinker disease (PRNP F198S) by [18F]Flortaucipir PET

Risacher, S. L., Farlow, M. R., Bateman, D. R., Epperson, F., Tallman, E. F., Richardson, R., Murrell, J. R., Unverzagt, F. W., Apostolova, L. G., Bonnin, J. M., Ghetti, B. & Saykin, A. J., Oct 29 2018, In : Acta neuropathologica communications. 6, 1, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study

Gordon, B. A., Blazey, T. M., Su, Y., Hari-Raj, A., Dincer, A., Flores, S., Christensen, J., McDade, E., Wang, G., Xiong, C., Cairns, N. J., Hassenstab, J., Marcus, D. S., Fagan, A. M., Jack, C. R., Hornbeck, R. C., Paumier, K. L., Ances, B. M., Berman, S. B., Brickman, A. M. & 20 others, Cash, D. M., Chhatwal, J. P., Correia, S., Förster, S., Fox, N. C., Graff-Radford, N. R., la Fougère, C., Levin, J., Masters, C. L., Rossor, M. N., Salloway, S., Saykin, A. J., Schofield, P. R., Thompson, P. M., Weiner, M. M., Holtzman, D. M., Raichle, M. E., Morris, J. C., Bateman, R. J. & Benzinger, T. L. S., Mar 2018, In : The Lancet Neurology. 17, 3, p. 241-250 10 p.

Research output: Contribution to journalArticle

61 Scopus citations
2016

Cerebral perfusion and gray matter changes associated with chemotherapy-induced peripheral neuropathy

Nudelman, K. N. H., McDonald, B. C., Wang, Y., Smith, D. J., West, J. D., O'Neill, D. P., Zanville, N. R., Champion, V. L., Schneider, B. P. & Saykin, A. J., Mar 1 2016, In : Journal of Clinical Oncology. 34, 7, p. 677-683 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

A novel Alzheimer disease locus located near the gene encoding tau protein

Jun, G., Ibrahim-Verbaas, C. A., Vronskaya, M., Lambert, J. C., Chung, J., Naj, A. C., Kunkle, B. W., Wang, L. S., Bis, J. C., Bellenguez, C., Harold, D., Lunetta, K. L., Destefano, A. L., Grenier-Boley, B., Sims, R., Beecham, G. W., Smith, A. V., Chouraki, V., Hamilton-Nelson, K. L., Ikram, M. A. & 332 others, Fievet, N., Denning, N., Martin, E. R., Schmidt, H., Kamatani, Y., Dunstan, M. L., Valladares, O., Laza, A. R., Zelenika, D., Ramirez, A., Foroud, T. M., Choi, S. H., Boland, A., Becker, T., Kukull, W. A., Van Der Lee, S. J., Pasquier, F., Cruchaga, C., Beekly, D., Fitzpatrick, A. L., Hanon, O., Gill, M., Barber, R., Gudnason, V., Campion, D., Love, S., Bennett, D. A., Amin, N., Berr, C., Tsolaki, M., Buxbaum, J. D., Lopez, O. L., Deramecourt, V., Fox, N. C., Cantwell, L. B., Tárraga, L., Dufouil, C., Hardy, J., Crane, P. K., Eiriksdottir, G., Hannequin, D., Clarke, R., Evans, D., Mosley, T. H., Letenneur, L., Brayne, C., Maier, W., De Jager, P., Emilsson, V., Dartigues, J. F., Hampel, H., Kamboh, M. I., De Bruijn, R. F. A. G., Tzourio, C., Pastor, P., Larson, E. B., Rotter, J. I., O'Donovan, M. C., Montine, T. J., Nalls, M. A., Mead, S., Reiman, E. M., Jonsson, P. V., Holmes, C., St George-Hyslop, P. H., Boada, M., Passmore, P., Wendland, J. R., Schmidt, R., Morgan, K., Winslow, A. R., Powell, J. F., Carasquillo, M., Younkin, S. G., Jakobsdóttir, J., Kauwe, J. S. K., Wilhelmsen, K. C., Rujescu, D., Nöthen, M. M., Hofman, A., Jones, L., Haines, J. L., Psaty, B. M., Van Broeckhoven, C., Holmans, P., Launer, L. J., Mayeux, R., Lathrop, M., Goate, A. M., Escott-Price, V., Seshadri, S., Pericak-Vance, M. A., Amouyel, P., Williams, J., Van Duijn, C. M., Schellenberg, G. D., Farrer, L. A., Adams, P. M., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barmada, M. M., Barnes, L. L., Beach, T. G., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cribbs, D. H., Crocco, E. A., DeCarli, C., DeKosky, S. T., Yesim Demirci, F., Dick, M., Dickson, D. W., Doody, R. S., Duara, R., Ertekin-Taner, N., Faber, K. M., Fairchild, T. J., Fallon, K. B., Farlow, M. R., Ferris, S., Frosch, M. P., Galasko, D. R., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Glass, J. D., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Harrell, L. E., Head, E., Honig, L. S., Huebinger, R. M., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Karydas, A., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lin, C. F., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Morris, J. C., Mukherjee, S., Murrell, J. R., Myers, A. J., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Partch, A., Paulson, H. L., Perry, W., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reisch, J. S., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Royall, D. R., Sager, M. A., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Wishnek, S., Woltjer, R. L., Wright, C. B., Wu, C. K., Yu, C. E., Yu, L., Thomas, C., Gerrish, A., Chapman, J., Stretton, A., Morgan, A., Oldham, H., Owen, M. J., Kehoe, P. G., Medway, C., Brown, K., Lord, J., Turton, J., Hooper, N. M., Vardy, E., Warren, J. D., Schott, J. M., Uphill, J., Hollingworth, P., Ryan, N., Rossor, M., Collinge, J., Ben-Shlomo, Y., Makrina, D., Gkatzima, O., Lupton, M., Koutroumani, M., Avramidou, D., Germanou, A., Jessen, F., Riedel-Heller, S., Dichgans, M., Heun, R., Kölsch, H., Schürmann, B., Herold, C., Lacour, A., Drichel, D., Hoffmann, P., Kornhuber, J., Gu, W., Feulner, T., Mayhaus, M., Pichler, S., Riemenschneider, M., van den Bussche, H., Lawlor, B., Lynch, A., Mann, D., Smith, A. D., Warden, D., Wilcock, G., Heuser, I., Wiltfang, J., Frölich, L., Hüll, M., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Singleton, A. B., Guerreiro, R., Russo, G., Jöckel, K. H., Moebus, S., Klopp, N., Wichmann, H. E., Ma, L., Bisceglio, G., Fisher, E., Warner, N., Pickering-Brown, S., Craig, D., Johnston, J. A., McGuinness, B., Todd, S., Rubinsztein, D. C., Lovestone, S., Bayer, A., Gallacher, J., Proitsi, P. & Ortega-Cubero, S., Jan 1 2016, In : Molecular Psychiatry. 21, 1, p. 108-117 10 p.

Research output: Contribution to journalArticle

84 Scopus citations

White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network

Lee, S., Viqar, F., Zimmerman, M. E., Narkhede, A., Tosto, G., Benzinger, T. L. S., Marcus, D. S., Fagan, A. M., Goate, A., Fox, N. C., Cairns, N. J., Holtzman, D. M., Buckles, V., Ghetti, B., McDade, E., Martins, R. N., Saykin, A. J., Masters, C. L., Ringman, J. M., Ryan, N. S. & 12 others, Förster, S., Laske, C., Schofield, P. R., Sperling, R. A., Salloway, S., Correia, S., Jack, C., Weiner, M., Bateman, R. J., Morris, J. C., Mayeux, R. & Brickman, A. M., Jun 1 2016, In : Annals of neurology. 79, 6, p. 929-939 11 p.

Research output: Contribution to journalArticle

110 Scopus citations
2018
33 Scopus citations

Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states

Mahjoub, I., Mahjoub, M. A., Rekik, I., Weiner, M., Aisen, P., Petersen, R., Jack, C., Jagust, W., Trojanowki, J., Toga, A., Beckett, L., Green, R., Saykin, A., Morris, J., Shaw, L., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R. & 221 others, Dolen, S., Schneider, L., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J., Lord, J., Mason, S., Albers, C., Knopman, D., Johnson, K., Doody, R., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L., Bell, K., Ances, B., Carroll, M., Creech, M., Franklin, E., Mintun, M., Schneider, S., Oliver, A., Marson, D., Grifth, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Natelson Love, M., Grossman, H., Mitsis, E., Shah, R., Detoledo-Morrell, L., Duara, R., Varon, D., Greig, M., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J., Cerbone, B., Michel, C., Pogorelec, D., Rusinek, H., De Leon, M., Glodzik, L., De Santi, S., Doraiswamy, P., Petrella, J., Borges-Neto, S., Wong, T., Coleman, E., Smith, C., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Porsteinsson, A., Goldstein, B., Martin, K., Makino, K., Ismail, M., Brand, C., Mulnard, R., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A., Lah, J., Cellar, J., Burns, J., Swerdlow, R., Brooks, W., Apostolova, L., Tingus, K., Woo, E., Silverman, D., Lu, P., Bartzokis, G., Graf-Radford, N., Parftt, F., Kendall, T., Johnson, H., Farlow, M., Hake, A. M., Matthews, B., Brosch, J., Herring, S., Hunt, C., Dyck, C., Carson, R., MacAvoy, M., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Mesulam, M. M., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Turner, R. S., Johnson, K., Reynolds, B., Sperling, R., Johnson, K., Marshall, G., Yesavage, J., Taylor, J., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M., Belden, C., Jacobson, S., Sirrel, S., Kowall, N., Killiany, R., Budson, A., Norbash, A., Johnson, P. L., Obisesan, T., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C., Potkin, S., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D., Kataki, M., Adeli, A., Zimmerman, E., Celmins, D., Brown, A., Pearlson, G., Blank, K., Anderson, K., Flashman, L., Seltzer, M., Hynes, M., Santulli, R., Sink, K., Gordineer, L., Williamson, J., Garg, P., Watkins, F., Ott, B., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H., Miller, B., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Raj, B. A. & Fargher, K., Dec 1 2018, In : Scientific reports. 8, 1, 4103.

Research output: Contribution to journalArticle

24 Scopus citations
2017

Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty

Du, L., Liu, K., Yao, X., Yan, J., Risacher, S. L., Han, J., Guo, L., Saykin, A. J., Shen, L., Weiner, M. W., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Morris, J., Shaw, L. M. & 293 others, Khachaturian, Z., Sorensen, G., Carrillo, M., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M. M., Potter, W., Snyder, P., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Balasubramanian, A. B., Mason, J., Sim, I., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., Decarli, C., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Landau, S., Cairns, N. J., Franklin, E., Taylor-Reinwald, L., Lee, V., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T. M., Potkin, S., Faber, K., Kim, S., Nho, K., Thal, L., Buckholtz, N., Albert, M., Frank, R., Hsiao, J., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Pavlik, V., Shibley, V., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Creech, M. L., Franklin, E., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Geldmacher, D., Love, M. N., Griffith, R., Clark, D., Brockington, J., Roberson, E., Grossman, H., Mitsis, E., Shah, R. C., Detoledo-Morrell, L., Duara, R., Greig-Custo, M. T., Barker, W., Onyike, C., D'Agostino, D., Kielb, S., Sadowski, M., Sheikh, M. O., Ulysse, A., Gaikwad, M., Murali Doraiswamy, P., Petrella, J. R., Borges-Neto, S., Wong, T. Z., Coleman, E., Arnold, S. E., Karlawish, J. H., Wolk, D. A., Clark, C. M., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Lopez, O. L., Oakley, M. A., Simpson, D. M., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Ismail, M. S., Brand, C., Preda, A., Nguyen, D., Womack, K., Mathews, D., Quiceno, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Swerdlow, R. H., Brooks, W. M., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Poki-Walker, K., Farlow, M. R., Marie Hake, A., Matthews, B. R., Brosch, J. R., Herring, S., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Mudge, B., Sossi, V., Feldman, H., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Rogers, J., Trost, D., Kertesz, A., Bernick, C., Munic, D., Rogalski, E., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Scott Turner, R., Johnson, K., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Lynn Johnson, P., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Tariot, P., Burke, A., Milliken, A. M., Trncic, N., Fleisher, A., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Kelly, B., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Flashman, L. A., Seltzer, M., Hynes, M. L., Santulli, R. B., Sink, K. M., Gordineer, L., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Tremont, G., Daiello, L. A., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S. K., Ekstam Smith, K., Koleva, H., Nam, K. W., Shim, H., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Ashok Raj, B. & Fargher, K., Dec 1 2017, In : Scientific reports. 7, 1, 14052.

Research output: Contribution to journalArticle

3 Scopus citations
2019

Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group

Jia, T., Chu, C., Liu, Y., van Dongen, J., Papastergios, E., Armstrong, N. J., Bastin, M. E., Carrillo-Roa, T., den Braber, A., Harris, M., Jansen, R., Liu, J., Luciano, M., Ori, A. P. S., Roiz Santiañez, R., Ruggeri, B., Sarkisyan, D., Shin, J., Sungeun, K., Tordesillas Gutiérrez, D. & 62 others, van’t Ent, D., Ames, D., Artiges, E., Bakalkin, G., Banaschewski, T., Bokde, A. L. W., Brodaty, H., Bromberg, U., Brouwer, R., Büchel, C., Burke Quinlan, E., Cahn, W., de Zubicaray, G. I., Ehrlich, S., Ekström, T. J., Flor, H., Fröhner, J. H., Frouin, V., Garavan, H., Gowland, P., Heinz, A., Hoare, J., Ittermann, B., Jahanshad, N., Jiang, J., Kwok, J. B., Martin, N. G., Martinot, J. L., Mather, K. A., McMahon, K. L., McRae, A. F., Nees, F., Papadopoulos Orfanos, D., Paus, T., Poustka, L., Sämann, P. G., Schofield, P. R., Smolka, M. N., Stein, D. J., Strike, L. T., Teeuw, J., Thalamuthu, A., Trollor, J., Walter, H., Wardlaw, J. M., Wen, W., Whelan, R., Apostolova, L. G., Binder, E. B., Boomsma, D. I., Calhoun, V., Crespo-Facorro, B., Deary, I. J., Hulshoff Pol, H., Ophoff, R. A., Pausova, Z., Sachdev, P. S., Saykin, A., Wright, M. J., Thompson, P. M., Schumann, G. & Desrivières, S., Jan 1 2019, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Biological Hallmarks of Cancer in Alzheimer’s Disease

Nudelman, K. N. H., McDonald, B. C., Lahiri, D. K. & Saykin, A. J., Oct 1 2019, In : Molecular Neurobiology. 56, 10, p. 7173-7187 15 p.

Research output: Contribution to journalReview article

4 Scopus citations
2016

Novel genetic loci underlying human intracranial volume identified through genome-wide association

Adams, H. H. H., Hibar, D. P., Chouraki, V., Stein, J. L., Nyquist, P. A., Rentería, M. E., Trompet, S., Arias-Vasquez, A., Seshadri, S., Desrivières, S., Beecham, A. H., Jahanshad, N., Wittfeld, K., Van Der Lee, S. J., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S. & 322 others, Armstrong, N. J., Athanasiu, L., Axelsson, T., Beiser, A., Bernard, M., Bis, J. C., Blanken, L. M. E., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chauhan, G., Chen, Q., Ching, C. R. K., Cuellar-Partida, G., Braber, A. D., Doan, N. T., Ehrlich, S., Filippi, I., Ge, T., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Greven, C. U., Grimm, O., Griswold, M. E., Guadalupe, T., Hass, J., Haukvik, U. K., Hilal, S., Hofer, E., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liao, J., Liewald, D. C. M., Lopez, L. M., Luciano, M., Macare, C., Marquand, A., Matarin, M., Mather, K. A., Mattheisen, M., Mazoyer, B., McKay, D. R., McWhirter, R., Milaneschi, Y., Mirza-Schreiber, N., Muetzel, R. L., Maniega, S. M., Nho, K., Nugent, A. C., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pappa, I., Pirpamer, L., Pudas, S., Pütz, B., Rajan, K. B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-Santiañez, R., Rommelse, N., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Thomson, R., Tordesillas-Gutierrez, D., Toro, R., Trabzuni, D., Vaidya, D., Van Der Grond, J., Van Der Meer, D., Van Donkelaar, M. M. J., Van Eijk, K. R., Van Erp, T. G. M., Van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Woldehawariat, G., Wolf, C., Wolfers, T., Xu, B., Yanek, L. R., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Aggarwal, N. T., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., Van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Chen, C., Cheng, C. Y., Cichon, S., Cookson, M. R., Corvin, A., Crespo-Facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., De Geus, E. J. C., De Jager, P. L., De Zubicaray, G. I., Delanty, N., Depondt, C., Destefano, A. L., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Erk, S., Espeseth, T., Evans, D. A., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Foroud, T. M., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Grabe, H. J., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B. C., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J. J., Pol, H. E. H., Ikeda, M., Ikram, M. K., Jack, C. R., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Longstreth, W. T., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J. L., Mattay, V. S., McDonald, C., McIntosh, A. M., McMahon, K. L., McMahon, F. J., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. 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J., Decarli, C., Schmidt, H., Martin, N. G., De Craen, A. J. M., Wright, M. J., Launer, L. J., Schumann, G., Fornage, M., Franke, B., Debette, S., Medland, S. E., Ikram, M. A. & Thompson, P. M., Dec 1 2016, In : Nature Neuroscience. 19, 12, p. 1569-1582 14 p.

Research output: Contribution to journalArticle

73 Scopus citations

Association between anticholinergic medication use and cognition, brain metabolism, and brain atrophy in cognitively normal older adults

Alzheimer's Disease Neuroimaging Initiative, Jun 2016, In : JAMA Neurology. 73, 6, p. 721-732 12 p.

Research output: Contribution to journalArticle

95 Scopus citations
2017

Recent publications from the Alzheimer's Disease Neuroimaging Initiative: Reviewing progress toward improved AD clinical trials

Alzheimer's Disease Neuroimaging Initiative, Apr 1 2017, In : Alzheimer's and Dementia. 13, 4, p. e1-e85

Research output: Contribution to journalReview article

76 Scopus citations

Association of plasma neurofilament light with neurodegeneration in patients with Alzheimer disease

Alzheimer's Disease Neuroimaging Initiative, May 2017, In : JAMA Neurology. 74, 5, p. 557-566 10 p.

Research output: Contribution to journalArticle

2016

Variants in ACPP are associated with cerebrospinal fluid Prostatic Acid Phosphatase levels

for the Alzheimer's Disease Neuroimaging Initiative, Jun 29 2016, In : BMC genomics. 17, 439.

Research output: Contribution to journalArticle

1 Scopus citations
2017

Metabolic network failures in Alzheimer's disease: A biochemical road map

Alzheimer's Disease Neuroimaging Initiative and the Alzheimer Disease Metabolomics Consortium, Sep 2017, In : Alzheimer's and Dementia. 13, 9, p. 965-984 20 p.

Research output: Contribution to journalArticle

74 Scopus citations

The Alzheimer's Disease Neuroimaging Initiative 3: Continued innovation for clinical trial improvement

Alzheimer's Disease Neuroimaging Initiative, May 2017, In : Alzheimer's and Dementia. 13, 5, p. 561-571 11 p.

Research output: Contribution to journalReview article

45 Scopus citations

Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers

Alzheimer’s Disease Neuroimaging Initiative (ADNI) & The Alzheimer Disease Genetic Consortium (ADGC), May 1 2017, In : Acta Neuropathologica. 133, 5, p. 839-856 18 p.

Research output: Contribution to journalArticle

38 Scopus citations
2019

The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory

The Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dec 1 2019, In : Nature communications. 10, 1, 1766.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2016

Integration of bioinformatics and imaging informatics for identifying rare PSEN1 variants in Alzheimer's disease

Nho, K., Horgusluoglu, E., Kim, S., Risacher, S. L., Kim, D., Foroud, T., Aisen, P. S., Petersen, R. C., Jack, C. R., Shaw, L. M., Trojanowski, J. Q., Weiner, M. W., Green, R. C., Toga, A. W. & Saykin, A. J., Aug 12 2016, In : BMC Medical Genomics. 9, 30.

Research output: Contribution to journalArticle

9 Scopus citations
2018

Subcortical brain iron deposition and cognitive performance in older women with breast cancer receiving adjuvant chemotherapy: A pilot MRI study

Chen, B. T., Ghassaban, K., Jin, T., Patel, S. K., Ye, N., Sun, C. L., Kim, H., Rockne, R. C., Mark Haacke, E., Root, J. C., Saykin, A. J., Ahles, T. A., Holodny, A. I., Prakash, N., Mortimer, J., Waisman, J., Yuan, Y., Somlo, G., Li, D., Yang, R. & 4 others, Tan, H., Katheria, V., Morrison, R. & Hurria, A., Dec 2018, In : Magnetic Resonance Imaging. 54, p. 218-224 7 p.

Research output: Contribution to journalArticle

3 Scopus citations
2017

Brain explorer for connectomic analysis

for the Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2017, In : Brain Informatics. 4, 4, p. 253-269 17 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Heritability estimation of reliable connectomic features

Xie, L., Amico, E., Salama, P., Wu, Y. C., Fang, S., Sporns, O., Saykin, A. J., Goñi, J., Yan, J. & Shen, L., Jan 1 2018, Connectomics in NeuroImaging - 2nd International Workshop, CNI 2018, Held in Conjunction with MICCAI 2018, Proceedings. Wu, G., Schirmer, M. D., Chung, A. W., Rekik, I. & Munsell, B. (eds.). Springer Verlag, p. 58-66 9 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11083 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations
2016

Prospective assessment of white matter integrity in adult stem cell transplant recipients

Correa, D. D., Wang, Y., West, J. D., Peck, K. K., Root, J. C., Baser, R. E., Thaler, H. T., Shore, T. B., Jakubowski, A., Saykin, A. J. & Relkin, N., Jun 1 2016, In : Brain Imaging and Behavior. 10, 2, p. 486-496 11 p.

Research output: Contribution to journalArticle

8 Scopus citations
2017

A fast SCCA algorithm for big data analysis in brain imaging genetics

Alzheimer’s Disease Neuroimaging Initiative, 2017, Graphs in Biomedical Image Analysis, Computational Anatomy and Imaging Genetics - 1st International Workshop, GRAIL 2017 6th International Workshop, MFCA 2017 and 3rd International Workshop, MICGen 2017 Held in Conjunction with MICCAI 2017, Proceedings. Springer Verlag, Vol. 10551 LNCS. p. 210-219 10 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10551 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Genome-wide network-based pathway analysis of CSF t-tau/Aβ1-42 ratio in the ADNI cohort

for the Alzheimer's Disease Neuroimaging Initiative, May 30 2017, In : BMC genomics. 18, 1, 421.

Research output: Contribution to journalArticle

5 Scopus citations
2019

A dirty multi-task learning method for multi-modal brain imaging genetics

for the Alzheimer’s Disease Neuroimaging Initiative, Jan 1 2019, Medical Image Computing and Computer Assisted Intervention – MICCAI 2019 - 22nd International Conference, Proceedings. Shen, D., Yap, P-T., Liu, T., Peters, T. M., Khan, A., Staib, L. H., Essert, C. & Zhou, S. (eds.). Springer, p. 447-455 9 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11767 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2017

Predicting interrelated Alzheimer’s disease outcomes via new self-learned structured low-rank model

Wang, X., Liu, K., Yan, J., Risacher, S. L., Saykin, A. J., Shen, L. & Huang, H., Jan 1 2017, Information Processing in Medical Imaging - 25th International Conference, IPMI 2017, Proceedings. Zhu, H., Niethammer, M., Styner, M., Zhu, H., Shen, D., Yap, P-T., Aylward, S. & Oguz, I. (eds.). Springer Verlag, p. 198-209 12 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10265 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations
2019

Exercise prevents obesity-induced cognitive decline and white matter damage in mice

Graham, L. C., Grabowska, W. A., Chun, Y., Risacher, S. L., Philip, V. M., Saykin, A. J., Sukoff Rizzo, S. J. & Howell, G. R., Aug 2019, In : Neurobiology of Aging. 80, p. 154-172 19 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Genome-wide network-assisted association and enrichment study of amyloid imaging phenotype in alzheimer’s disease

Alzheimer’s Disease Neuroimaging Initiative, Jan 1 2019, In : Current Alzheimer research. 16, 13, p. 1163-1174 12 p.

Research output: Contribution to journalArticle

1 Scopus citations
2016

Structured sparse CCA for brain imaging genetics via graph OSCAR

Du, L., Huang, H., Yan, J., Kim, S., Risacher, S., Inlow, M., Moore, J., Saykin, A. & Shen, L., Aug 26 2016, In : BMC Systems Biology. 10, 68.

Research output: Contribution to journalArticle

6 Scopus citations
2018

Multiple incomplete views clustering via non-negative matrix factorization with its application in Alzheimer's disease analysis

Liu, K., Wang, H., Risacher, S., Saykin, A. & Shen, L., May 23 2018, 2018 IEEE 15th International Symposium on Biomedical Imaging, ISBI 2018. IEEE Computer Society, Vol. 2018-April. p. 1402-1405 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Topographic staging of tau positron emission tomography images

Alzheimer's Disease Neuroimaging Initiative, Jan 1 2018, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 10, p. 221-231 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Joint high-order multi-task feature learning to predict the progression of Alzheimer’s disease

ADNI, Jan 1 2018, Medical Image Computing and Computer Assisted Intervention – MICCAI 2018 - 21st International Conference, 2018, Proceedings. Schnabel, J. A., Davatzikos, C., Alberola-López, C., Fichtinger, G. & Frangi, A. F. (eds.). Springer Verlag, p. 555-562 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11070 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations
2017

Age at injury is associated with the long-term cognitive outcome of traumatic brain injuries

Alzheimer's Disease Neuroimaging Initiative, Jan 1 2017, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 6, p. 196-200 5 p.

Research output: Contribution to journalArticle

7 Scopus citations
2018

Presymptomatic atrophy in autosomal dominant Alzheimer's disease: A serial magnetic resonance imaging study

for the & Dominantly Inherited Alzheimer Network (DIAN), Jan 2018, In : Alzheimer's and Dementia. 14, 1, p. 43-53 11 p.

Research output: Contribution to journalArticle

16 Scopus citations
2016

Quantitative Amyloid imaging in autosomal Dominant Alzheimer's disease: Results from the DIAN study group

Su, Y., Blazey, T. M., Owen, C. J., Christensen, J. J., Friedrichsen, K., Joseph-Mathurin, N., Wang, Q., Hornbeck, R. C., Ances, B. M., Snyder, A. Z., Cash, L. A., Koeppe, R. A., Klunk, W. E., Galasko, D., Brickman, A. M., McDade, E., Ringman, J. M., Thompson, P. M., Saykin, A. J., Ghetti, B. & 16 others, Sperling, R. A., Johnson, K. A., Salloway, S. P., Schofield, P. R., Masters, C. L., Villemagne, V. L., Fox, N. C., Förster, S., Chen, K., Reiman, E. M., Xiong, C., Marcus, D. S., Weiner, M. W., Morris, J. C., Bateman, R. J. & Benzinger, T. L. S., Mar 2016, In : PloS one. 11, 3, e0152082.

Research output: Contribution to journalArticle

23 Scopus citations

Alpha-synuclein (SNCA) polymorphisms exert protective effects on memory after mild traumatic brain injury

Shee, K., Lucas, A., Flashman, L. A., Nho, K., Tsongalis, G. J., McDonald, B. C., Saykin, A. J., McAllister, T. W. & Rhodes, C. H., Sep 6 2016, In : Neuroscience Letters. 630, p. 241-246 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2019

Disruption of gene co-expression network along the progression of Alzheimer's disease

Upadhyaya, Y., Xie, L., Salama, P., Nho, K., Saykin, A. J. & Yan, J., May 2019, 2019 IEEE EMBS International Conference on Biomedical and Health Informatics, BHI 2019 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 8834551. (2019 IEEE EMBS International Conference on Biomedical and Health Informatics, BHI 2019 - Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2016

Mood, stress and longevity: convergence on ANK3

Rangaraju, S., Levey, D. F., Nho, K., Jain, N., Andrews, K. D., Le-Niculescu, H., Salomon, D. R., Saykin, A., Petrascheck, M. & Niculescu, A., May 24 2016, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

10 Scopus citations
2018

Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

The Genetic FTD Initiative (GENFI) & The Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dec 1 2018, In : Nature communications. 9, 1, 4273.

Research output: Contribution to journalArticle

22 Scopus citations