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2017
11 Citations (Scopus)

TERT Promoter Mutations Occur Frequently in Urothelial Papilloma and Papillary Urothelial Neoplasm of Low Malignant Potential

Cheng, L., Montironi, R. & Lopez-Beltran, A., Mar 1 2017, In : European Urology. 71, 3, p. 497-498 2 p.

Research output: Contribution to journalLetter

Papilloma
Mutation
Neoplasms
2019

Predicting outcomes in non-muscle invasive (Ta/T1) bladder cancer: the role of molecular grade based on luminal/basal phenotype

Rebola, J., Aguiar, P., Blanca, A., Montironi, R., Cimadamore, A., Cheng, L., Henriques, V., Lobato-Faria, P. & Lopez-Beltran, A., Jan 1 2019, In : Virchows Archiv.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Phenotype
Neoplasms
Urinary Bladder
Multivariate Analysis
2018
3 Citations (Scopus)

Prostate cancer with cribriform morphology: diagnosis, aggressiveness, molecular pathology and possible relationships with intraductal carcinoma

Montironi, R., Cimadamore, A., Gasparrini, S., Mazzucchelli, R., Santoni, M., Massari, F., Cheng, L., Lopez-Beltran, A. & Scarpelli, M., Jul 3 2018, In : Expert Review of Anticancer Therapy. 18, 7, p. 685-693 9 p.

Research output: Contribution to journalReview article

Carcinoma, Intraductal, Noninfiltrating
Molecular Pathology
Prostatic Neoplasms
Neoplasm Grading
Growth
3 Citations (Scopus)

Intratumoural heterogeneity may hinder precision medicine strategies in patients with clear cell renal cell carcinoma

Raspollini, M. R., Montagnani, I., Montironi, R., Castiglione, F., Martignoni, G., Cheng, L. & Lopez-Beltran, A., May 1 2018, In : Journal of Clinical Pathology. 71, 5, p. 467-471 5 p.

Research output: Contribution to journalArticle

Precision Medicine
Renal Cell Carcinoma
Neoplasms
Mutation
Genes
2016
32 Citations (Scopus)

Epithelial to Mesenchymal Transition in Renal Cell Carcinoma: Implications for Cancer Therapy

Piva, F., Giulietti, M., Santoni, M., Occhipinti, G., Scarpelli, M., Lopez-Beltran, A., Cheng, L., Principato, G. & Montironi, R., Mar 3 2016, (Accepted/In press) In : Molecular Diagnosis and Therapy. p. 1-7 7 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Renal Cell Carcinoma
Neoplasms
Therapeutics
Phenotype
2017
2 Citations (Scopus)

Müllerian Adenosarcoma of the Urinary Bladder: Clinicopathologic and Immunohistochemical Features With Novel Genetic Aberrations

Sanfrancesco, J., Williamson, S. R., Kum, J. B., Zhang, S., Wang, M., Lopez-Beltran, A., Montironi, R., Gardner, T. & Cheng, L., 2017, (Accepted/In press) In : Clinical Genitourinary Cancer.

Research output: Contribution to journalArticle

Adenosarcoma
Urinary Bladder
Proto-Oncogenes
GTP Phosphohydrolases
Staining and Labeling
2019

Predicting biochemical recurrence after radical prostatectomy: the role of prognostic grade group and index tumor nodule

Vau, N., Henriques, V., Cheng, L., Blanca, A., Fonseca, J., Montironi, R., Cimadamore, A. & Lopez-Beltran, A., Nov 2019, In : Human pathology. 93, p. 6-15 10 p.

Research output: Contribution to journalArticle

Prostatectomy
Recurrence
Neoplasms
Survival
Prostate
2016
15 Citations (Scopus)

Extranodal Extension of Nodal Metastases Is a Poor Prognostic Indicator in Gastric Cancer: a Systematic Review and Meta-analysis

Veronese, N., Fassan, M., Wood, L. D., Stubbs, B., Solmi, M., Capelli, P., Pea, A., Nottegar, A., Sergi, G., Manzato, E., Carraro, S., Maruzzo, M., Cataldo, I., Bagante, F., Barbareschi, M., Cheng, L., Bencivenga, M., de Manzoni, G. & Luchini, C., Jul 13 2016, (Accepted/In press) In : Journal of Gastrointestinal Surgery. p. 1-7 7 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Meta-Analysis
Confidence Intervals
Neoplasm Metastasis
Odds Ratio
2019
1 Citation (Scopus)

Perineural Invasion is a Strong Prognostic Moderator in Ampulla of Vater Carcinoma: A Meta-analysis

Luchini, C., Veronese, N., Nottegar, A., Riva, G., Pilati, C., Mafficini, A., Stubbs, B., Simbolo, M., Mombello, A., Corbo, V., Cheng, L., Yachida, S., Wood, L. D., Lawlor, R. T., Salvia, R. & Scarpa, A., Jan 1 2019, In : Pancreas. 48, 1, p. 70-76 7 p.

Research output: Contribution to journalArticle

Ampulla of Vater
Meta-Analysis
Confidence Intervals
Carcinoma
Recurrence
2018
2 Citations (Scopus)

Micropapillary urothelial carcinoma: evaluation of HER2 status and immunohistochemical characterization of the molecular subtype

Zinnall, U., Weyerer, V., Compérat, E., Camparo, P., Gaisa, N. T., Knuechel-Clarke, R., Perren, A., Lugli, A., Toma, M., Baretton, G., Kristiansen, G., Wirtz, R. M., Cheng, L., Wullich, B., Stoehr, R., Hartmann, A. & Bertz, S., Oct 1 2018, In : Human Pathology. 80, p. 55-64 10 p.

Research output: Contribution to journalArticle

Carcinoma
Urinary Bladder Neoplasms
erbB-2 Genes
Mutation
In Situ Hybridization
2017
11 Citations (Scopus)

Mirna expression in bladder cancer and their potential role in clinical practice

Blanca, A., Cheng, L., Montironi, R., Moch, H., Massari, F., Fiorentino, M., Raspollini, M. R., Scarpelli, M. & Lopez-Beltran, A., Jan 1 2017, In : Current Drug Metabolism. 18, 8, p. 712-722 11 p.

Research output: Contribution to journalReview article

MicroRNAs
Urinary Bladder Neoplasms
Genes
High-Throughput Nucleotide Sequencing
Tumor Suppressor Genes
2019
6 Citations (Scopus)

Variants and new entities of bladder cancer

Lopez-Beltran, A., Henriques, V., Montironi, R., Cimadamore, A., Raspollini, M. R. & Cheng, L., Jan 1 2019, In : Histopathology. 74, 1, p. 77-96 20 p.

Research output: Contribution to journalReview article

Urinary Bladder Neoplasms
Carcinoma
Male Genitalia
Neoplasms
Observation
2016

Handling of the surgical specimen and pathology reporting of malignant germ cell and sex cord-stromal tumors of the testis

Scarpelli, M., Mazzucchelli, R., Santoni, M., Sotte, V., Conti, A., Lopez-Beltran, A., Cheng, L. & Montironi, R., May 2 2016, Pathology of Testicular and Penile Neoplasms. Springer International Publishing, p. 165-170 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sex Cord-Gonadal Stromal Tumors
Specimen Handling
Surgical Pathology
Germ Cells
Testis
2019
2 Citations (Scopus)

Plasmacytoid/diffuse urothelial carcinoma: a single-institution immunohistochemical and molecular study of 69 patients

Perrino, C. M., Eble, J., Kao, C. S., Whaley, R. D., Cheng, L., Idrees, M., Hashemi-Sadraei, N., Monn, M. F., Kaimakliotis, H. Z., Bandali, E. & Grignon, D., Aug 1 2019, In : Human pathology. 90, p. 27-36 10 p.

Research output: Contribution to journalArticle

Carcinoma
Urinary Bladder
Catenins
Chromosome Deletion
Mutation
2017
8 Citations (Scopus)

Pathology Imagebase—a reference image database for standardization of pathology

The ISUP Pathology Imagebase Expert Panel, Nov 1 2017, In : Histopathology. 71, 5, p. 677-685 9 p.

Research output: Contribution to journalArticle

Databases
Pathology
Politics
Urinary Bladder
Kidney
2019

Molecular evidence supporting the precursor nature of atypical adenomatous hyperplasia of the prostate

Cheng, L., Montironi, R., Davidson, D., Wang, M., Lopez-Beltran, A. & Zhang, S., Jul 1 2019, In : Molecular Carcinogenesis. 58, 7, p. 1272-1278 7 p.

Research output: Contribution to journalArticle

Hyperplasia
Prostate
Telomere Shortening
Prostatic Intraepithelial Neoplasia
Adenocarcinoma
2017
5 Citations (Scopus)
Seminal Vesicles
Adipose Tissue
Prostate
Prostatic Neoplasms
Lymph Nodes
1 Citation (Scopus)

Immunotherapy in genitourinary cancers: Where are we going?

Bianconi, M., Faloppi, L., Lopez-Beltran, A., Cheng, L., Cimadamore, A., Gasparrini, S., Massari, F., Scarpelli, M. & Montironi, R., Jan 1 2017, In : Expert Review of Precision Medicine and Drug Development. 2, 2, p. 73-78 6 p.

Research output: Contribution to journalArticle

Urogenital Neoplasms
Immunotherapy
Neoplasms
Neoplasm Antigens
Renal Cell Carcinoma
2018
3 Citations (Scopus)

Emerging prognostic biomarkers in testicular germ cell tumors: Looking beyond established practice

Chovanec, M., Albany, C., Mego, M., Montironi, R., Cimadamore, A. & Cheng, L., Jan 1 2018, In : Frontiers in Oncology. 8, NOV, 571.

Research output: Contribution to journalReview article

Open Access
Biomarkers
Germ Cell and Embryonal Neoplasms
Fetal Proteins
Neoplasms
Testicular Neoplasms
2019

Extramammary Paget disease of the penis closely mimicking the penile analogue of stratified mucin-producing intraepithelial lesion

Cimadamore, A., Scarpelli, M., Cheng, L., Lopez-Beltran, A. & Montironi, R., Apr 1 2019, In : Minerva Urologica e Nefrologica. 71, 2, p. 189-190 2 p.

Research output: Contribution to journalLetter

Extramammary Paget's Disease
Penis
Mucins

Current and emerging bladder cancer biomarkers with an emphasis on urine biomarkers

Lopez-Beltran, A., Cheng, L., Gevaert, T., Blanca, A., Cimadamore, A., Santoni, M., Massari, F., Scarpelli, M., Raspollini, M. R. & Montironi, R., Jan 1 2019, (Accepted/In press) In : Expert Review of Molecular Diagnostics.

Research output: Contribution to journalReview article

Tumor Biomarkers
Urinary Bladder Neoplasms
Biomarkers
Urine
DNA
2016
15 Citations (Scopus)

Cholesterol sulfonation enzyme, SULT2B1b, modulates AR and cell growth properties in prostate cancer

Vickman, R. E., Crist, S. A., Kerian, K., Eberlin, L., Graham Cooks, R., Burcham, G. N., Buhman, K. K., Hu, C. D., Mesecar, A. D., Cheng, L. & Ratliff, T. L., Sep 1 2016, In : Molecular Cancer Research. 14, 9, p. 776-786 11 p.

Research output: Contribution to journalArticle

Androgen Receptors
Prostatic Neoplasms
Cholesterol
Enzymes
Growth
2017
2 Citations (Scopus)

Pathology and molecular updates in tumors of the prostate: towards a personalized approach

Gasparrini, S., Cimadamore, A., Mazzucchelli, R., Scarpelli, M., Massari, F., Raspollini, M. R., Galosi, A. B., Lopez-Beltran, A., Cheng, L. & Montironi, R., Aug 3 2017, In : Expert Review of Molecular Diagnostics. 17, 8, p. 781-789 9 p.

Research output: Contribution to journalReview article

Molecular Pathology
Prostate
Prostatic Neoplasms
Neoplasms
Carcinoma, Intraductal, Noninfiltrating
2019
Prostatic Neoplasms
DNA
Neoplasms
2017
Endometriosis
Fertility
Urinary Bladder
3 Citations (Scopus)

Concomitant bladder cancer and prostate cancer: Challenges and controversies

Lopez-Beltran, A., Cheng, L., Montorsi, F., Scarpelli, M., Raspollini, M. R. & Montironi, R., Oct 1 2017, In : Nature Reviews Urology. 14, 10, p. 620-629 10 p.

Research output: Contribution to journalReview article

Urinary Bladder Neoplasms
Prostatic Neoplasms
Muscles
Urologic Neoplasms
Digital Rectal Examination
2019

Microbiome and cancers, with focus on genitourinary tumors

Cimadamore, A., Santoni, M., Massari, F., Gasparrini, S., Cheng, L., Lopez-Beltran, A., Montironi, R. & Scarpelli, M., Jan 1 2019, In : Frontiers in Oncology. 9, MAR, 178.

Research output: Contribution to journalComment/debate

Open Access
Microbiota
Renal Cell Carcinoma
Immunotherapy
Prostatic Neoplasms
Neoplasms
2018

Prostate cancer grading in 2018: Limitations, implementations, cribriform morphology, and biological markers

Montironi, R., Cimadamore, A., Cheng, L., Lopez-Beltran, A. & Scarpelli, M., Jan 1 2018, In : International Journal of Biological Markers. 33, 4, p. 331-334 4 p.

Research output: Contribution to journalEditorial

Pathology
Prostatic Neoplasms
Neoplasm Grading
Biomarkers
Growth
2016
8 Citations (Scopus)

Current Histopathologic and Molecular Characterisations of Prostate Cancer: Towards Individualised Prognosis and Therapies

Santoni, M., Scarpelli, M., Mazzucchelli, R., Lopez-Beltran, A., Cheng, L., Epstein, J. I., Cascinu, S., Briganti, A., Catto, J. W., Montorsi, F. & Montironi, R., Feb 1 2016, In : European Urology. 69, 2, p. 186-190 5 p.

Research output: Contribution to journalArticle

Fusion Oncogene Proteins
Precision Medicine
Neoplasm Grading
Neoplasm Staging
Androgen Receptors
2019

Targeted therapy for solid tumors and risk of hypertension: a meta-analysis of 68077 patients from 93 phase III studies

Santoni, M., Conti, A., Massari, F., Di Nunno, V., Faloppi, L., Galizia, E., Morbiducci, J., Piva, F., Buti, S., Iacovelli, R., Ferretti, B., Cimadamore, A., Scarpelli, M., Lopez-Beltran, A., Cheng, L., Battelli, N. & Montironi, R., Dec 2 2019, In : Expert Review of Cardiovascular Therapy. 17, 12, p. 917-927 11 p.

Research output: Contribution to journalArticle

Meta-Analysis
Hypertension
Neoplasms
Incidence
Therapeutics
1 Citation (Scopus)

Contemporary grading of prostate cancer: 2017 update for pathologists and clinicians

Gasparrini, S., Cimadamore, A., Scarpelli, M., Massari, F., Doria, A., Mazzucchelli, R., Cheng, L., Lopez-Beltran, A. & Montironi, R., Jan 1 2019, In : Asian Journal of Andrology. 21, 1, p. 19-23 5 p.

Research output: Contribution to journalReview article

Neoplasm Grading
Prostatic Neoplasms
Pathology
Pathologists
Therapeutics
2017
1 Citation (Scopus)

Epigenetic modifications and modulators in prostate cancer

Cimadamore, A., Gasparrini, S., Scarpelli, M., Doria, A., Mazzucchelli, R., Massari, F., Cheng, L., Lopez-Beltran, A. & Montironi, R., Jan 1 2017, In : Critical Reviews in Oncogenesis. 22, 5-6, p. 439-450 12 p.

Research output: Contribution to journalArticle

Epigenomics
Prostatic Neoplasms
DNA Methylation
Acetylation
MicroRNAs
Seminal Vesicles
Adipose Tissue
Prostate
Prostatic Neoplasms
Lymph Nodes
2016
4 Citations (Scopus)

Prostate cancer glands with cribriform architecture and with glomeruloid features should be considered as Gleason pattern 4 and not pattern 3

Minardi, D., Mazzucchelli, R., Scarpelli, M., Massari, F., Ciccarese, C., Lopez-Beltran, A., Cheng, L. & Montironi, R., Jun 1 2016, In : Future Oncology. 12, 12, p. 1431-1433 3 p.

Research output: Contribution to journalArticle

Neoplasm Grading
Prostatic Neoplasms
Adenocarcinoma
2017

From Gleason Grading System and High-grade Tertiary Patterns to Grade Groups and Integrated Quantitative Gleason Score

Montironi, R., Cheng, L., Scarpelli, M. & Lopez-Beltran, A., 2017, (Accepted/In press) In : European Urology.

Research output: Contribution to journalArticle

Neoplasm Grading
2016
8 Citations (Scopus)

An overview of emerging immunotargets of genitourinary tumors

Montironi, R., Santoni, M., Cheng, L., Lopez-Beltran, A., Massari, F., Matrana, M. R., Moch, H. & Scarpelli, M., Jun 1 2016, In : Current Drug Targets. 17, 7, p. 750-756 7 p.

Research output: Contribution to journalArticle

Tumors
Neoplasms
Weapons
Lymphocytes
Macrophages

Cysts and epithelial proliferations of the testicular collecting system

Lopez-Beltran, A., Canas-Marques, R., Raspollini, M. R., Montironi, R., Scarpelli, M. & Cheng, L., May 2 2016, Pathology of Testicular and Penile Neoplasms. Springer International Publishing, p. 171-189 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2018

Quick steps toward precision medicine in renal cell carcinoma

Massari, F., Santoni, M., Di Nunno, V., Cimadamore, A., Battelli, N., Scarpelli, M., Cheng, M., Lopez-Beltran, A., Cheng, L. & Montironi, R., Jan 1 2018, (Accepted/In press) In : Expert Review of Precision Medicine and Drug Development.

Research output: Contribution to journalArticle

Precision Medicine
Renal Cell Carcinoma
2016
9 Citations (Scopus)

Neoadjuvant dasatinib for muscle-invasive bladder cancer with tissue analysis of biologic activity

Hahn, N. M., Knudsen, B. S., Daneshmand, S., Koch, M., Bihrle, R., Foster, R., Gardner, T., Cheng, L., Liu, Z., Breen, T., Fleming, M. T., Lance, R., Corless, C. L., Alva, A. S., Shen, S. S., Huang, F., Gertych, A., Gallick, G. E., Mallick, J., Ryan, C. & 4 others, Galsky, M. D., Lerner, S. P., Posadas, E. M. & Sonpavde, G., Jan 1 2016, In : Urologic Oncology. 34, 1

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Muscles
Urinary Bladder
Carcinoma
Cystectomy
3 Citations (Scopus)

Re: Daniel M. Geynisman. Anti-programmed Cell Death Protein 1 (PD-1) Antibody Nivolumab Leads to a Dramatic and Rapid Response in Papillary Renal Cell Carcinoma with Sarcomatoid and Rhabdoid Features. Eur Urol 2015;68:912-4

Piva, F., Santoni, M., Scarpelli, M., Briganti, A., Lopez-Beltran, A., Cheng, L., Berardi, R., Montorsi, F. & Montironi, R., 2016, (Accepted/In press) In : European Urology.

Research output: Contribution to journalArticle

Programmed Cell Death 1 Receptor
Renal Cell Carcinoma
Antibodies
nivolumab
2017

Design and in-vivo evaluation of next-generation laparoscopic HIFU kidney probe

Seip, R., Morris, A., Chaluisan, R., Clanton, J., Carlson, R., Carr, J., Johnson, C., Sanghvi, N., Smith, J., Matam, M., Morris, J., Chopra, S., Gill, I., Shum, C. F., Sundaram, C., Cheng, L. & Carol, M., Oct 31 2017, 2017 IEEE International Ultrasonics Symposium, IUS 2017. IEEE Computer Society, 8092872

Research output: Chapter in Book/Report/Conference proceedingConference contribution

kidneys
ablation
evaluation
probes
miniaturization
2016
3 Citations (Scopus)

Emerging immunotargets in genitourinary tumors

Montironi, R., Santoni, M., Massari, F., Lopez-Beltran, A., Cheng, L., Berardi, R. & Scarpelli, M., Jun 1 2016, In : Current Drug Targets. 17, 7, p. 748-749 2 p.

Research output: Contribution to journalArticle

CD274 Antigen
Programmed Cell Death 1 Receptor
Urogenital Neoplasms
CTLA-4 Antigen
Immunotherapy
2019
6 Citations (Scopus)

Novel Therapeutic Approaches and Targets Currently Under Evaluation for Renal Cell Carcinoma: Waiting for the Revolution

Mollica, V., Di Nunno, V., Gatto, L., Santoni, M., Cimadamore, A., Cheng, L., Lopez-Beltran, A., Montironi, R., Pisconti, S., Battelli, N. & Massari, F., Jan 1 2019, In : Clinical Drug Investigation.

Research output: Contribution to journalReview article

Renal Cell Carcinoma
Death Domain Receptors
Glucocorticoid-Induced TNFR-Related Protein
OX40 Receptor
Immunotherapy
3 Citations (Scopus)

Circulating tumor cells in renal cell carcinoma: Recent findings and future challenges

Santoni, M., Cimadamore, A., Cheng, L., Lopez-Beltran, A., Battelli, N., Massari, F., Scarpelli, M., Galosi, A. B., Bracarda, S. & Montironi, R., Jan 1 2019, In : Frontiers in Oncology. 9, APR, 228.

Research output: Contribution to journalComment/debate

Open Access
Circulating Neoplastic Cells
Renal Cell Carcinoma
1 Citation (Scopus)

STAT6 Expression in Solitary Fibrous Tumor and Histologic Mimics: A Single Institution Experience

Saeed, O., Zhang, S., Cheng, L., Lin, J., Alruwaii, F. & Chen, S., Jan 1 2019, (Accepted/In press) In : Applied Immunohistochemistry and Molecular Morphology.

Research output: Contribution to journalArticle

Solitary Fibrous Tumors
Staining and Labeling
Sarcoma
Coloring Agents
Dermatofibrosarcoma
2016
21 Citations (Scopus)

Loss of expression of the SWI/SNF complex is a frequent event in undifferentiated/dedifferentiated urothelial carcinoma of the urinary tract

Agaimy, A., Bertz, S., Cheng, L., Hes, O., Junker, K., Keck, B., Lopez-Beltran, A., Stöckle, M., Wullich, B. & Hartmann, A., Sep 1 2016, In : Virchows Archiv. 469, 3, p. 321-330 10 p.

Research output: Contribution to journalArticle

Urinary Tract
Carcinoma
Neoplasms
Kidney Pelvis
Chromatin Assembly and Disassembly
8 Citations (Scopus)

Chromosome 12p abnormalities and IMP3 expression in prepubertal pure testicular teratomas

Cornejo, K. M., Cheng, L., Church, A., Wang, M. & Jiang, Z., Mar 1 2016, In : Human Pathology. 49, p. 54-60 7 p.

Research output: Contribution to journalArticle

Chromosome Aberrations
Isochromosomes
Teratoma
Surgical Pathology
Orchiectomy

Evolving terminology and classification of urologic tumors and precursor lesions: An update based on the 2016 WHO classification

Huang, W., Chen, J., Teng, X. & Cheng, L., Jul 1 2016, In : Chinese Journal of Pathology. 45, 7, p. 433-434 2 p.

Research output: Contribution to journalComment/debate

Terminology
Neoplasms

Early detection of prostate cancer: Can we have our cake and eat it too?

Masterson, T., Cary, K. C. & Cheng, L., Mar 3 2016, In : Expert Review of Anticancer Therapy. 16, 3, p. 247-249 3 p.

Research output: Contribution to journalArticle

Mass Screening
Prostate-Specific Antigen
Early Detection of Cancer
Prostatic Neoplasms