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  • Liang Cheng
2019

Contemporary best practice in the management of urothelial carcinomas of the renal pelvis and ureter

Bianconi, M., Cimadamore, A., Faloppi, L., Scartozzi, M., Santoni, M., Lopez-Beltran, A., Cheng, L., Scarpelli, M. & Montironi, R., Jan 1 2019, In : Therapeutic Advances in Urology. 11

Research output: Contribution to journalReview article

2 Scopus citations
2018

Physiological stretch induced proliferation of human urothelial cells via integrin α6-FAK signaling pathway

Gao, X., Wei, T., Liao, B., Ai, J., Zhou, L., Gong, L., Chen, Y., He, Q., Cheng, L. & Wang, K., Sep 2018, In : Neurourology and Urodynamics. 37, 7, p. 2114-2120 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2016

Handling of the surgical specimen and pathology reporting of penile neoplasms

Montironi, R., Mazzucchelli, R., Santoni, M., Sotte, V., Lopez-Beltran, A., Cheng, L. & Scarpelli, M., May 2 2016, Pathology of Testicular and Penile Neoplasms. Springer International Publishing, p. 275-280 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cysts and epithelial proliferations of the testicular collecting system

Lopez-Beltran, A., Canas-Marques, R., Raspollini, M. R., Montironi, R., Scarpelli, M. & Cheng, L., May 2 2016, Pathology of Testicular and Penile Neoplasms. Springer International Publishing, p. 171-189 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Genetic mutations in accordance with a low malignant potential tumour are not demonstrated in clear cell papillary renal cell carcinoma

Raspollini, M. R., Castiglione, F., Cheng, L., Montironi, R. & Lopez-Beltran, A., Jun 2016, In : Journal of clinical pathology. 69, 6, p. 547-550 4 p.

Research output: Contribution to journalArticle

8 Scopus citations

Handling of the surgical specimen and pathology reporting of malignant germ cell and sex cord-stromal tumors of the testis

Scarpelli, M., Mazzucchelli, R., Santoni, M., Sotte, V., Conti, A., Lopez-Beltran, A., Cheng, L. & Montironi, R., May 2 2016, Pathology of Testicular and Penile Neoplasms. Springer International Publishing, p. 165-170 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Multiple and bilateral kidney tumors with clear cells of three different histotypes: A case report with clinicopathologic and molecular study

Raspollini, M. R., Castiglione, F., Martignoni, G., Lapini, A., Cheng, L., Montironi, R. & Lopez-Beltran, A., Jul 1 2016, In : APMIS. 124, 7, p. 619-623 5 p.

Research output: Contribution to journalArticle

2 Scopus citations
2019

Predicting biochemical recurrence after radical prostatectomy: the role of prognostic grade group and index tumor nodule

Vau, N., Henriques, V., Cheng, L., Blanca, A., Fonseca, J., Montironi, R., Cimadamore, A. & Lopez-Beltran, A., Nov 2019, In : Human pathology. 93, p. 6-15 10 p.

Research output: Contribution to journalArticle

2016
8 Scopus citations
2017

Understanding the Genetic Landscape of Small Cell Carcinoma of the Urinary Bladder and Implications for Diagnosis, Prognosis, and Treatment: A Review

Kouba, E. J. & Cheng, L., Nov 1 2017, In : JAMA oncology. 3, 11, p. 1570-1578 9 p.

Research output: Contribution to journalReview article

12 Scopus citations
2016

High fidelity of driver chromosomal alterations among primary and metastatic renal cell carcinomas: Implications for tumor clonal evolution and treatment

Kouba, E. J., Eble, J. N., Simper, N., Grignon, D. J., Wang, M., Zhang, S., Wang, L., Martignoni, G., Williamson, S. R., Brunelli, M., Luchini, C., Calió, A. & Cheng, L., Nov 1 2016, In : Modern Pathology. 29, 11, p. 1347-1357 11 p.

Research output: Contribution to journalArticle

7 Scopus citations
2019

LncRNA-p21 alters the antiandrogen enzalutamide-induced prostate cancer neuroendocrine differentiation via modulating the EZH2/STAT3 signaling

Luo, J., Wang, K., Yeh, S., Sun, Y., Liang, L., Xiao, Y., Xu, W., Niu, Y., Cheng, L., Maity, S. N., Jiang, R. & Chang, C., Dec 1 2019, In : Nature communications. 10, 1, 2571.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations
2017

Testicular cancer: The usage of central review for pathology diagnosis of orchiectomy specimens

Harari, S. E., Sassoon, D. J., Priemer, D. S., Jacob, J. M., Eble, J. N., Caliò, A., Grignon, D. J., Idrees, M., Albany, C., Masterson, T. A., Hanna, N. H., Foster, R. S., Ulbright, T. M., Einhorn, L. H. & Cheng, L., Oct 2017, In : Urologic Oncology: Seminars and Original Investigations. 35, 10, p. 605.e9-605.e16

Research output: Contribution to journalArticle

6 Scopus citations
2019

Plasmacytoid/diffuse urothelial carcinoma: a single-institution immunohistochemical and molecular study of 69 patients

Perrino, C. M., Eble, J., Kao, C. S., Whaley, R. D., Cheng, L., Idrees, M., Hashemi-Sadraei, N., Monn, M. F., Kaimakliotis, H. Z., Bandali, E. & Grignon, D., Aug 2019, In : Human pathology. 90, p. 27-36 10 p.

Research output: Contribution to journalArticle

3 Scopus citations
2016

Renal cell carcinoma with TFE3 translocation and succinate dehydrogenase B mutation

Calió, A., Grignon, D., Stohr, B. A., Williamson, S. R., Eble, J. & Cheng, L., Dec 2 2016, (Accepted/In press) In : Modern Pathology.

Research output: Contribution to journalArticle

16 Scopus citations

Emerging molecular pathways and targets in neuroendocrine prostate cancer

Monn, M. F., Montironi, R., Lopez-Beltran, A. & Cheng, L., 2016, In : Translational Cancer Research. 5, p. S282-S285

Research output: Contribution to journalComment/debate

Significance of Programmed Death Ligand 1 (PD-L1) Immunohistochemical Expression in Colorectal Cancer

Wang, L., Ren, F., Wang, Q., Baldridge, L. A., Monn, M. F., Fisher, K. W., Sheng, W., Zhou, X., Du, X. & Cheng, L., Apr 1 2016, In : Molecular Diagnosis and Therapy. 20, 2, p. 175-181 7 p.

Research output: Contribution to journalArticle

21 Scopus citations
2017

Solitary fibrous tumour of the genitourinary tract: A clinicopathological study of 11 cases and their association with the NAB2-STAT6 fusion gene

Kouba, E., Simper, N. B., Chen, S., Williamson, S. R., Grignon, D. J., Eble, J. N., MacLennan, G. T., Montironi, R., Lopez-Beltran, A., Osunkoya, A. O., Zhang, S., Wang, M., Wang, L., Tran, T., Emerson, R. E., Baldrige, L. A., Monn, M. F., Linos, K. & Cheng, L., Jun 1 2017, In : Journal of clinical pathology. 70, 6, p. 508-514 7 p.

Research output: Contribution to journalArticle

8 Scopus citations
2018

Renal cell carcinoma with angioleiomyoma-like stroma and clear cell papillary renal cell carcinoma: exploring SDHB protein immunohistochemistry and the relationship to tuberous sclerosis complex

Williamson, S. R., Hornick, J. L., Eble, J. N., Gupta, N. S., Rogers, C. G., True, L., Grignon, D. J. & Cheng, L., May 2018, In : Human pathology. 75, p. 10-15 6 p.

Research output: Contribution to journalArticle

8 Scopus citations
2016

Extranodal Extension of Nodal Metastases Is a Poor Prognostic Indicator in Gastric Cancer: a Systematic Review and Meta-analysis

Veronese, N., Fassan, M., Wood, L. D., Stubbs, B., Solmi, M., Capelli, P., Pea, A., Nottegar, A., Sergi, G., Manzato, E., Carraro, S., Maruzzo, M., Cataldo, I., Bagante, F., Barbareschi, M., Cheng, L., Bencivenga, M., de Manzoni, G. & Luchini, C., Jul 13 2016, (Accepted/In press) In : Journal of Gastrointestinal Surgery. p. 1-7 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Widespread telomere instability in prostatic lesions

Tu, L., Huda, N., Grimes, B. R., Slee, R. B., Bates, A. M., Cheng, L. & Gilley, D., May 1 2016, In : Molecular Carcinogenesis. 55, 5, p. 842-852 11 p.

Research output: Contribution to journalArticle

5 Scopus citations
2018

Myeloid-derived suppressor cells inhibit T cell activation through nitrating LCK in mouse cancers

Feng, S., Cheng, X., Zhang, L., Lu, X., Chaudhary, S., Teng, R., Frederickson, C., Champion, M. M., Zhao, R., Cheng, L., Gong, Y., Deng, H. & Lu, X., Oct 2 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 40, p. 10094-10099 6 p.

Research output: Contribution to journalArticle

19 Scopus citations
2020

Intraductal carcinoma of the prostate is an aggressive form of invasive carcinoma and should be graded

Samaratunga, H., Delahunt, B., Egevad, L., Srigley, J. R., Billis, A., Bostwick, D. G., Camparo, P., Cheng, L., Clouston, D., Denham, J., Furusato, B., Hartmann, A., Jufe, L., Kench, J., Kenwright, D. N., Kristiansen, G., Leite, K. R. M., MacLennan, G. T., Merrimen, J., Moch, H. & 11 others, Oxley, J., Pan, C. C., Paner, G., Ro, J., Sesterhenn, I. A. M., Shanks, J., Thunders, M., Tsuzuki, T., Wheeler, T., Yaxley, J. W. & Varma, M., Feb 2020, In : Pathology. 52, 2, p. 192-196 5 p.

Research output: Contribution to journalReview article

1 Scopus citations
2017

Oligometastases in Genitourinary Tumors: Recent Insights and Future Molecular Diagnostic Approach

Conti, A., D'Elia, C., Cheng, M., Santoni, M., Piva, F., Brunelli, M., Lopez-Beltran, A., Giulietti, M., Scarpelli, M., Pycha, A., Galosi, A. B., Artibani, W., Cheng, L., Montironi, R., Battelli, N. & Lusuardi, L., 2017, (Accepted/In press) In : European Urology, Supplements.

Research output: Contribution to journalArticle

5 Scopus citations

Morphologic Variants of Epithelial and Neuroendocrine Tumors of the Prostate. The Pathologist's Point of View

Montironi, R., Gasparrini, S., Cimadamore, A., Mazzucchelli, R., Massari, F., Cheng, L., Lopez-Beltran, A., Briganti, A. & Scarpelli, M., 2017, (Accepted/In press) In : European Urology, Supplements.

Research output: Contribution to journalArticle

2 Scopus citations
2016

Early detection of prostate cancer: Can we have our cake and eat it too?

Masterson, T., Cary, K. C. & Cheng, L., Mar 3 2016, In : Expert Review of Anticancer Therapy. 16, 3, p. 247-249 3 p.

Research output: Contribution to journalArticle

2017

Emerging biomarkers in genitourinary tumors

Montironi, R., Lopez-Beltran, A. & Cheng, L., Jan 1 2017, In : Current Drug Metabolism. 18, 8, p. 690-691 2 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Circulating tumor cells: A reliable biomarker for prostate cancer treatment assessment?

Ciccarese, C., Montironi, R., Fiorentino, M., Martignoni, G., Brunelli, M., Iacovelli, R., Lopez-Beltranf, A., Cheng, L., Scarpelli, M., Moch, H., Tortora, G. & Massari, F., Jan 1 2017, In : Current Drug Metabolism. 18, 8, p. 692-699 8 p.

Research output: Contribution to journalReview article

7 Scopus citations
2019

Genitourinary Tumors: Update on Molecular Biomarkers for Diagnosis, Prognosis and Prediction of Response to Therapy

Cimadamore, A., Scarpelli, M., Santoni, M., Massari, F., Tartari, F., Cerqueti, R., Lopez-Beltran, A., Cheng, L. & Montironi, R., Jan 1 2019, In : Current drug metabolism. 20, 4, p. 305-312 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

The molecular characterization and therapeutic strategies of papillary renal cell carcinoma

Chen, Q., Cheng, L. & Li, Q., Feb 1 2019, In : Expert Review of Anticancer Therapy. 19, 2, p. 169-175 7 p.

Research output: Contribution to journalReview article

2020

Sequential or Concomitant Inhibition of Cyclin-Dependent Kinase 4/6 Before mTOR Pathway in Hormone-Positive HER2 Negative Breast Cancer: Biological Insights and Clinical Implications

Occhipinti, G., Romagnoli, E., Santoni, M., Cimadamore, A., Sorgentoni, G., Cecati, M., Giulietti, M., Battelli, N., Maccioni, A., Storti, N., Cheng, L., Principato, G., Montironi, R. & Piva, F., Apr 15 2020, In : Frontiers in Genetics. 11, 349.

Research output: Contribution to journalReview article

Open Access

Microsatellite instability and mismatch repair deficiency in the era of precision immuno-oncology

Mann, S. A. & Cheng, L., Jan 2 2020, In : Expert Review of Anticancer Therapy. 20, 1, p. 1-4 4 p.

Research output: Contribution to journalEditorial

Open Access
2019

Key role of obesity in genitourinary tumors with emphasis on urothelial and prostate cancers

Santoni, M., Cimadamore, A., Massari, F., Piva, F., Aurilio, G., Martignetti, A., Scarpelli, M., Di Nunno, V., Gatto, L., Battelli, N., Cheng, L., Lopez-Beltran, A. & Montironi, R., Sep 2019, In : Cancers. 11, 9, 1225.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2018

Next-Generation Sequencing to Detect Deletion of RB1 and ERBB4 Genes in Chromophobe Renal Cell Carcinoma: A Potential Role in Distinguishing Chromophobe Renal Cell Carcinoma from Renal Oncocytoma

Liu, Q., Cornejo, K. M., Cheng, L., Hutchinson, L., Wang, M., Zhang, S., Tomaszewicz, K., Cosar, E. F., Woda, B. A. & Jiang, Z., Apr 2018, In : American Journal of Pathology. 188, 4, p. 846-852 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Small-cell Carcinomas of the Urinary Bladder and Prostate: TERT Promoter Mutation Status Differentiates Sites of Malignancy and Provides Evidence of Common Clonality Between Small-cell Carcinoma of the Urinary Bladder and Urothelial Carcinoma

Priemer, D. S., Wang, M., Zhang, S., Lopez-Beltran, A., Kouba, E., Montironi, R., Davidson, D. D., MacLennan, G. T., Wang, L., Osunkoya, A. O., Deng, Y., Emerson, R. E. & Cheng, L., Dec 2018, In : European Urology Focus. 4, 6, p. 880-888 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Emerging prognostic biomarkers in testicular germ cell tumors: Looking beyond established practice

Chovanec, M., Albany, C., Mego, M., Montironi, R., Cimadamore, A. & Cheng, L., Jan 1 2018, In : Frontiers in Oncology. 8, NOV, 571.

Research output: Contribution to journalReview article

Open Access
6 Scopus citations
2019

Circulating tumor cells in renal cell carcinoma: Recent findings and future challenges

Santoni, M., Cimadamore, A., Cheng, L., Lopez-Beltran, A., Battelli, N., Massari, F., Scarpelli, M., Galosi, A. B., Bracarda, S. & Montironi, R., 2019, In : Frontiers in Oncology. 9, APR, 228.

Research output: Contribution to journalComment/debate

Open Access
6 Scopus citations
2020

Practical molecular testing in a clinical genitourinary service

Magers, M. J. & Cheng, L., Jan 1 2020, In : Archives of Pathology and Laboratory Medicine. 144, 3, p. 277-289 13 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

Use of CD42b immunohistochemical stain for the detection of Histoplasma

Ku, N. K., Pullarkat, S. T., Kim, Y. S., Cheng, L. & O'Malley, D., Feb 2018, In : Annals of Diagnostic Pathology. 32, p. 47-50 4 p.

Research output: Contribution to journalArticle

2019

Editorial: Emerging biomarkers in genitourinary tumors

Montironi, R., Santoni, M., Cimadamore, A., Lopez-Beltran, A. & Cheng, L., Jan 1 2019, In : Frontiers in Oncology. 9, APR, 326.

Research output: Contribution to journalEditorial

Open Access
2 Scopus citations
2016

Atypical renal cysts a morphologic, immunohistochemical, and molecular study

Matoso, A., Chen, Y. B., Rao, V., Wang, L., Cheng, L. & Epstein, J. I., Jan 1 2016, In : American Journal of Surgical Pathology. 40, 2, p. 202-211 10 p.

Research output: Contribution to journalArticle

8 Scopus citations
2020

Report from the International Society of Urological Pathology (ISUP) Consultation Conference on Molecular Pathology of Urogenital Cancers. II. Molecular Pathology of Bladder Cancer: Progress and Challenges

Warrick, J. I., Knowles, M. A., Yves, A., Van Der Kwast, T., Grignon, D. J., Kristiansen, G., Egevad, L., Hartmann, A. & Cheng, L., Jan 1 2020, (Accepted/In press) In : American Journal of Surgical Pathology.

Research output: Contribution to journalArticle

1 Scopus citations
2016

Human papillomavirus (HPV)-induced neoplasia in the urinary bladder: A missing link?

Alexander, R. E., Wang, L., Lopez-Beltran, A., Emerson, R. E., Montironi, R., Pedrosa, J. A., Kaimakliotis, H. Z., Koch, M. O. & Cheng, L., Jun 2016, In : Histology and Histopathology. 31, 6, p. 595-600 6 p.

Research output: Contribution to journalReview article

6 Scopus citations
2018

Whole Slide Imaging Versus Microscopy for Primary Diagnosis in Surgical Pathology: A Multicenter Blinded Randomized Noninferiority Study of 1992 Cases (Pivotal Study)

Mukhopadhyay, S., Feldman, M. D., Abels, E., Ashfaq, R., Beltaifa, S., Cacciabeve, N. G., Cathro, H. P., Cheng, L., Cooper, K., Dickey, G. E., Gill, R. M., Heaton, R. P., Kerstens, R., Lindberg, G. M., Malhotra, R. K., Mandell, J. W., Manlucu, E. D., Mills, A. M., Mills, S. E., Moskaluk, C. A. & 14 others, Nelis, M., Patil, D. T., Przybycin, C. G., Reynolds, J. P., Rubin, B. P., Saboorian, M. H., Salicru, M., Samols, M. A., Sturgis, C. D., Turner, K. O., Wick, M. R., Yoon, J. Y., Zhao, P. & Taylor, C. R., 2018, In : American Journal of Surgical Pathology. 42, 1, p. 39-52 14 p.

Research output: Contribution to journalArticle

62 Scopus citations
2019

The human microbiota and prostate cancer: Friend or foe?

Massari, F., Mollica, V., Di Nunno, V., Gatto, L., Santoni, M., Scarpelli, M., Cimadamore, A., Lopez-Beltran, A., Cheng, L., Battelli, N., Montironi, R. & Brandi, G., Apr 2019, In : Cancers. 11, 4, 459.

Research output: Contribution to journalReview article

Open Access
6 Scopus citations
2016

Re: Daniel M. Geynisman. Anti-programmed Cell Death Protein 1 (PD-1) Antibody Nivolumab Leads to a Dramatic and Rapid Response in Papillary Renal Cell Carcinoma with Sarcomatoid and Rhabdoid Features. Eur Urol 2015;68:912-4

Piva, F., Santoni, M., Scarpelli, M., Briganti, A., Lopez-Beltran, A., Cheng, L., Berardi, R., Montorsi, F. & Montironi, R., 2016, (Accepted/In press) In : European Urology.

Research output: Contribution to journalArticle

4 Scopus citations
2018

Multidisciplinary clinic approach improves overall survival outcomes of patients with metastatic germ-cell tumors

Albany, C., Adra, N., Snavely, A. C., Cary, C., Masterson, T. A., Foster, R. S., Kesler, K., Ulbright, T. M., Cheng, L., Chovanec, M., Taza, F., Ku, K., Brames, M. J., Hanna, N. H. & Einhorn, L. H., Feb 1 2018, In : Annals of Oncology. 29, 2, p. 341-346 6 p.

Research output: Contribution to journalArticle

32 Scopus citations
2019

Detection of androgen receptor (AR) and AR-V7 in small cell prostate carcinoma: Diagnostic and therapeutic implications

Zhao, P., Zhu, Y., Cheng, L. & Luo, J., Jan 2019, In : Asian Journal of Urology. 6, 1, p. 109-113 5 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
2017

Complexity of the genomic landscape of renal cell carcinoma: Implications for targeted therapy and precision immuno-oncology

Sanfrancesco, J. M. & Cheng, L., Nov 1 2017, In : Critical Reviews in Oncology/Hematology. 119, p. 23-28 6 p.

Research output: Contribution to journalReview article

10 Scopus citations