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2017
18 Citations (Scopus)

Comparison of Parent, Peer, Psychiatric, and Cannabis Use Influences Across Stages of Offspring Alcohol Involvement: Evidence from the COGA Prospective Study

Bucholz, K. K., McCutcheon, V. V., Agrawal, A., Dick, D. M., Hesselbrock, V. M., Kramer, J. R., Kuperman, S., Nurnberger, J., Salvatore, J. E., Schuckit, M. A., Bierut, L. J., Foroud, T., Chan, G., Hesselbrock, M., Meyers, J. L., Edenberg, H. & Porjesz, B., Feb 1 2017, In : Alcoholism: Clinical and Experimental Research. 41, 2, p. 359-368 10 p.

Research output: Contribution to journalArticle

Cannabis
Psychiatry
Alcohols
Prospective Studies
Wounds and Injuries
3 Citations (Scopus)

Associations of parental alcohol use disorders and parental separation with offspring initiation of alcohol, cigarette and cannabis use and sexual debut in high-risk families

Mccutcheon, V. V., Agrawal, A., Kuo, S. I. C., Su, J., Dick, D. M., Meyers, J. L., Edenberg, H., Nurnberger, J., Kramer, J. R., Kuperman, S., Schuckit, M. A., Hesselbrock, V. M., Brooks, A., Porjesz, B. & Bucholz, K. K., 2017, (Accepted/In press) In : Addiction.

Research output: Contribution to journalArticle

Cannabis
Tobacco Products
Alcohols
Parents
Tobacco Use
1 Citation (Scopus)

A GABRA2 polymorphism improves a model for prediction of drinking initiation

Kuperman, S., Chan, G., Kramer, J., Wetherill, L., Acion, L., Edenberg, H., Foroud, T., Nurnberger, J., Agrawal, A., Anokhin, A., Brooks, A., Hesselbrock, V., Hesselbrock, M., Schuckit, M., Tischfield, J. & Liu, X., Sep 1 2017, In : Alcohol. 63, p. 1-8 8 p.

Research output: Contribution to journalArticle

Polymorphism
Drinking
Genotype
Self Report
Single Nucleotide Polymorphism
2019
2 Citations (Scopus)

The Genetic Relationship Between Alcohol Consumption and Aspects of Problem Drinking in an Ascertained Sample

Johnson, E. C., St. Pierre, C. L., Meyers, J. L., Aliev, F., McCutcheon, V. V., Lai, D., Dick, D. M., Goate, A. M., Kramer, J., Kuperman, S., Nurnberger, J., Schuckit, M. A., Porjesz, B., Edenberg, H., Bucholz, K. K. & Agrawal, A., Jun 1 2019, In : Alcoholism: Clinical and Experimental Research. 43, 6, p. 1113-1125 13 p.

Research output: Contribution to journalArticle

Alcohol Drinking
Drinking
Alcohols
Alcoholism
Area Under Curve
2017
6 Citations (Scopus)

Reciprocal relationships between substance use and disorders and suicidal ideation and suicide attempts in the Collaborative Study of the Genetics of Alcoholism

Agrawal, A., Tillman, R., Grucza, R. A., Nelson, E. C., McCutcheon, V. V., Few, L., Conner, K. R., Lynskey, M. T., Dick, D. M., Edenberg, H., Hesselbrock, V. M., Kramer, J. R., Kuperman, S., Nurnberger, J., Schuckit, M. A., Porjesz, B. & Bucholz, K. K., Apr 15 2017, In : Journal of Affective Disorders. 213, p. 96-104 9 p.

Research output: Contribution to journalArticle

Suicidal Ideation
Suicide
Alcoholism
Substance-Related Disorders
Marijuana Abuse
2018
8 Citations (Scopus)

The first implementation of the NIMH FAST-FAIL approach to psychiatric drug development

Krystal, A. D., Pizzagalli, D. A., Mathew, S. J., Sanacora, G., Keefe, R., Song, A., Calabrese, J., Goddard, A., Goodman, W., Lisanby, S. H., Smoski, M., Weiner, R., Iosifescu, D., Nurnberger, J., Szabo, S., Murrough, J., Shekhar, A. & Potter, W., Dec 28 2018, In : Nature Reviews Drug Discovery. 18, 1, p. 82-84 3 p.

Research output: Contribution to journalLetter

National Institute of Mental Health (U.S.)
Psychiatry
Pharmaceutical Preparations
2019

Association of polygenic liability for alcohol dependence and EEG connectivity in adolescence and young adulthood

Meyers, J. L., Chorlian, D. B., Johnson, E. C., Pandey, A. K., Kamarajan, C., Salvatore, J. E., Aliev, F., de Viteri, S. S. S., Zhang, J., Chao, M., Kapoor, M., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger, J., Tischfield, J., Goate, A., Foroud, T., Dick, D. M., Edenberg, H. J. & 2 others, Agrawal, A. & Porjesz, B., Oct 2019, In : Brain Sciences. 9, 10, 280.

Research output: Contribution to journalArticle

Open Access
Alcoholism
Electroencephalography
Alcohols
Genome-Wide Association Study
Brain
2017
4 Citations (Scopus)

Traumatic Stress Interacts With Bipolar Disorder Genetic Risk to Increase Risk for Suicide Attempts

Wilcox, H. C., Fullerton, J. M., Glowinski, A. L., Benke, K., Kamali, M., Hulvershorn, L., Stapp, E. K., Edenberg, H., Roberts, G. M. P., Ghaziuddin, N., Fisher, C., Brucksch, C., Frankland, A., Toma, C., Shaw, A. D., Kastelic, E., Miller, L., McInnis, M. G., Mitchell, P. B. & Nurnberger, J., Dec 1 2017, In : Journal of the American Academy of Child and Adolescent Psychiatry. 56, 12, p. 1073-1080 8 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Suicide
Substance-Related Disorders
Demography
Wounds and Injuries
1 Citation (Scopus)

Substance use disorders in adolescent and young adult relatives of probands with bipolar disorder: What drives the increased risk?

Hulvershorn, L., King, J., Monahan, P., Wilcox, H. C., Mitchell, P. B., Fullerton, J. M., Edenberg, H., Roberts, G. M. P., Kamali, M., Glowinski, A. L., Ghaziuddin, N., McInnis, M., Iyer-Eimerbrink, P. A. & Nurnberger, J., Oct 1 2017, In : Comprehensive Psychiatry. 78, p. 130-139 10 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Substance-Related Disorders
Young Adult
Drive
Diagnostic and Statistical Manual of Mental Disorders
2016
5 Citations (Scopus)

Interhemispheric white matter integrity in young people with bipolar disorder and at high genetic risk

Roberts, G., Wen, W., Frankland, A., Perich, T., Holmes-Preston, E., Levy, F., Lenroot, R. K., Hadzi-Pavlovic, D., Nurnberger, J., Breakspear, M. & Mitchell, P. B., Aug 1 2016, In : Psychological Medicine. 46, 11, p. 2385-2396 12 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Corpus Callosum
Major Depressive Disorder
Anisotropy
White Matter
2017

A Genetic Locus Associated With Depression: The Iceberg Begins to Melt

Nurnberger, J., Sep 1 2017, In : Biological Psychiatry. 82, 5, p. 304-305 2 p.

Research output: Contribution to journalComment/debate

Ice Cover
Genetic Loci
2016
2 Citations (Scopus)

Erratum: Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder (Nature (2015) 527 (95-99) DOI: 10.1038/nature15526)

Mertens, J., Wang, Q. W., Kim, Y., Yu, D. X., Pham, S., Yang, B., Zheng, Y., Diffenderfer, K. E., Zhang, J., Soltani, S., Eames, T., Schafer, S. T., Boyer, L., Marchetto, M. C., Nurnberger, J. I., Calabrese, J. R., Oedegaard, K. J., McCarthy, M. J., Zandi, P. P., Alda, M. & 6 others, Nievergelt, C. M., Mi, S., Brennand, K. J., Kelsoe, J. R., Gage, F. H. & Yao, J., Feb 11 2016, In : Nature. 530, 7589, p. 242 1 p.

Research output: Contribution to journalArticle

2019

Polygenic risk scores in psychiatry: Will they be useful for clinicians? [version 1; peer review: 4 approved]

Fullerton, J. M. & Nurnberger, J., Jan 1 2019, In : F1000Research. 8, 1293.

Research output: Contribution to journalReview article

Open Access
Peer Review
Psychiatry
Genes
Bipolar Disorder
Glossaries
2016
10 Citations (Scopus)

Risk factors for suicide in bipolar i disorder in two prospectively studied cohorts

Coryell, W., Kriener, A., Butcher, B., Nurnberger, J., McMahon, F., Berrettini, W. & Fiedorowicz, J., Jan 15 2016, In : Journal of Affective Disorders. 190, p. 1-5 5 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Suicide
Depression
Odds Ratio
National Institute of Mental Health (U.S.)
2018
3 Citations (Scopus)

Lithium-associated transcriptional regulation of CRMP1 in patient-derived olfactory neurons and symptom changes in bipolar disorder

McLean, C. K., Narayan, S., Lin, S. Y., Rai, N., Chung, Y., Hipolito, M. M. S., Cascella, N. G., Nurnberger, J., Ishizuka, K., Sawa, A. S. & Nwulia, E. A., Dec 1 2018, In : Translational Psychiatry. 8, 1, 81.

Research output: Contribution to journalArticle

Bipolar Disorder
Lithium
Neurons
Therapeutics
Antimanic Agents
2016
1 Citation (Scopus)

Genetics of psychiatric disorders

Nurnberger, J., Berrettini, W. & Niculescu, A., Jan 1 2016, The Medical Basis of Psychiatry: Fourth Edition. Springer New York, p. 553-600 48 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Inborn Genetic Diseases
Psychiatry
Genes
Attention Deficit Disorder with Hyperactivity
Autistic Disorder
2017
35 Citations (Scopus)

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bipolar Disorders Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jun 20 2017, In : Translational Psychiatry. 7, 6, p. e1155

Research output: Contribution to journalArticle

Borderline Personality Disorder
Genome-Wide Association Study
Bipolar Disorder
Schizophrenia
Depression
2018
5 Citations (Scopus)

What Should a Psychiatrist Know About Genetics? Review and Recommendations From the Residency Education Committee of the International Society of Psychiatric Genetics

Nurnberger, J., Austin, J., Berrettini, W. H., Besterman, A. D., DeLisi, L. E., Grice, D. E., Kennedy, J. L., Moreno-De-Luca, D., Potash, J. B., Ross, D. A., Schulze, T. G. & Zai, G., Nov 27 2018, In : The Journal of clinical psychiatry. 80, 1

Research output: Contribution to journalArticle

Internship and Residency
Psychiatry
Education
Committee Membership
Exome
2017
20 Citations (Scopus)

Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence

Andersen, A. M., Pietrzak, R. H., Kranzler, H. R., Ma, L., Zhou, H., Liu, X., Kramer, J., Kuperman, S., Edenberg, H., Nurnberger, J., Rice, J. P., Tischfield, J. A., Goate, A., Foroud, T., Meyers, J. L., Porjesz, B., Dick, D. M., Hesselbrock, V., Boerwinkle, E., Southwick, S. M. & 6 others, Krystal, J. H., Weissman, M. M., Levinson, D. F., Potash, J. B., Gelernter, J. & Han, S., Nov 1 2017, In : JAMA Psychiatry. 74, 11, p. 1153-1160 8 p.

Research output: Contribution to journalArticle

Major Depressive Disorder
Alcoholism
Genome-Wide Association Study
Veterans
Meta-Analysis
2019
5 Citations (Scopus)

Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism

Kapoor, M., Wang, J. C., Farris, S. P., Liu, Y., McClintick, J., Gupta, I., Meyers, J. L., Bertelsen, S., Chao, M., Nurnberger, J., Tischfield, J., Harari, O., Zeran, L., Hesselbrock, V., Bauer, L., Raj, T., Porjesz, B., Agrawal, A., Foroud, T., Edenberg, H. & 2 others, Mayfield, R. D. & Goate, A., Dec 1 2019, In : Translational psychiatry. 9, 1, 89.

Research output: Contribution to journalArticle

Alcoholism
Genome
Alcohol Drinking
Brain
Genes

Dr Nurnberger and Colleagues Reply

Nurnberger, J., Austin, J., Berrettini, W. H., Besterman, A. D., DeLisi, L. E., Grice, D. E., Kennedy, J. L., Moreno-De-Luca, D., Potash, J. B., Ross, D. A., Schulze, T. G. & Zai, G., Apr 9 2019, In : The Journal of clinical psychiatry. 80, 3

Research output: Contribution to journalArticle

Open Access
2018
3 Citations (Scopus)

Early-onset tobacco use and suicide-related behavior – A prospective study from adolescence to young adulthood

Korhonen, T., Sihvola, E., Latvala, A., Dick, D. M., Pulkkinen, L., Nurnberger, J., Rose, R. J. & Kaprio, J., Apr 2018, In : Addictive Behaviors. 79, p. 32-38 7 p.

Research output: Contribution to journalArticle

Tobacco
Tobacco Use
Suicide
Prospective Studies
Odds Ratio
2019

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jan 1 2019, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Open Access
Bipolar Disorder
Psychiatry
Schizophrenia
Depression
Major Depressive Disorder
2017
27 Citations (Scopus)

Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis

PGC ADHD Working Group & PGC Bipolar Disorder Working Group, Nov 1 2017, In : Biological Psychiatry. 82, 9, p. 634-641 8 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Attention Deficit Disorder with Hyperactivity
Bipolar Disorder
Meta-Analysis
Nucleotides
37 Citations (Scopus)

Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia

Anney, R. J. L., Ripke, S., Anttila, V., Grove, J., Holmans, P., Huang, H., Klei, L., Lee, P. H., Medland, S. E., Neale, B., Robinson, E., Weiss, L. A., Zwaigenbaum, L., Yu, T. W., Wittemeyer, K., Willsey, A. J., Wijsman, E. M., Werge, T., Wassink, T. H., Waltes, R. & 143 others, Walsh, C. A., Wallace, S., Vorstman, J. A. S., Vieland, V. J., Vicente, A. M., Vanengeland, H., Tsang, K., Thompson, A. P., Szatmari, P., Svantesson, O., Steinberg, S., Stefansson, K., Stefansson, H., State, M. W., Soorya, L., Silagadze, T., Scherer, S. W., Schellenberg, G. D., Sandin, S., Sanders, S. J., Saemundsen, E., Rouleau, G. A., Rogé, B., Roeder, K., Roberts, W., Reichert, J., Reichenberg, A., Rehnström, K., Regan, R., Poustka, F., Poultney, C. S., Piven, J., Pinto, D., Pericak-Vance, M. A., Pejovic-Milovancevic, M., Pedersen, M. G., Pedersen, C. B., Paterson, A. D., Parr, J. R., Pagnamenta, A. T., Oliveira, G., Nurnberger, J., Nordentoft, M., Murtha, M. T., Mouga, S., Mortensen, P. B., Mors, O., Morrow, E. M., Moreno-De-Luca, D., Monaco, A. P., Minshew, N., Merikangas, A., McMahon, W. M., McGrew, S. G., Mattheisen, M., Martsenkovsky, I., Martin, D. M., Mane, S. M., Magnusson, P., Magalhaes, T., Maestrini, E., Lowe, J. K., Lord, C., Levitt, P., Martin, C. L., Ledbetter, D. H., Leboyer, M., Lecouteur, A. S., Ladd-Acosta, C., Kolevzon, A., Klauck, S. M., Jacob, S., Iliadou, B., Hultman, C. M., Hougaard, D. M., Hertz-Picciotto, I., Hendren, R., Hansen, C. S., Haines, J. L., Guter, S. J., Grice, D. E., Green, J. M., Green, A., Goldberg, A. P., Gillberg, C., Gilbert, J., Gallagher, L., Freitag, C. M., Fombonne, E., Folstein, S. E., Fernandez, B., Fallin, M. D., Ercan-Sencicek, A. G., Ennis, S., Duque, F., Duketis, E., Delorme, R., Derubeis, S., Dejonge, M. V., Dawson, G., Cuccaro, M. L., Correia, C. T., Conroy, J., Conceição, I. C., Chiocchetti, A. G., Celestino-Soper, P. B. S., Casey, J., Cantor, R. M., Café, C., Bybjerg-Grauholm, J., Brennan, S., Bourgeron, T., Bolton, P. F., Bölte, S., Bolshakova, N., Betancur, C., Bernier, R., Beaudet, A. L., Battaglia, A., Bal, V. H., Baird, G., Bailey, A. J., Bækvad-Hansen, M., Bader, J. S., Bacchelli, E., Anagnostou, E., Amaral, D., Almeida, J., Børglum, A. D., Buxbaum, J. D., Chakravarti, A., Cook, E. H., Coon, H., Geschwind, D. H., Gill, M., Hallmayer, J., Palotie, A., Santangelo, S., Sutcliffe, J. S., Arking, D. E., Devlin, B., Daly, M. J. & Hakonarson, H., May 22 2017, In : Molecular Autism. 8, 1, 21.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Meta-Analysis
Schizophrenia
Genome
Genomics
3 Citations (Scopus)
Chromatin Assembly and Disassembly
Alcoholism
Chromatin
Sucrose
Alcohols
113 Citations (Scopus)

Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders

Psychiatric Genomics Consortium Autism Group & iPSYCH-Broad Autism Group, Jul 1 2017, In : Nature genetics. 49, 7, p. 978-985 8 p.

Research output: Contribution to journalArticle

Autism Spectrum Disorder
Schizophrenia
Phenotype
2016

Diagnostic Interview for Genetic Studies: validity and reliability of the Croatian version

Kralj, Ž., Dedić, M., Kovačević, A., Malički, M., Dedić, J., Pelivan, M., Vuković, D., Fisher, C., Kember, R. L., Nurnberger, J., Bućan, M. & Britvić, D., Oct 21 2016, (Accepted/In press) In : Psychiatric Genetics.

Research output: Contribution to journalArticle

Reproducibility of Results
Interviews
Mentally Ill Persons
Croatia
Aptitude
2018

21st-Century Genetics in Psychiatric Residency Training: How Do We Get There?

Besterman, A. D., Moreno-De-Luca, D. & Nurnberger, J., Jan 1 2018, (Accepted/In press) In : JAMA Psychiatry.

Research output: Contribution to journalArticle

Internship and Residency
Psychiatry
2019

A Pilot Follow-Up Study of Older Alcohol-Dependent COGA Adults

Chan, G., Kramer, J. R., Schuckit, M. A., Hesselbrock, V., Bucholz, K. K., Edenberg, H. J., Acion, L., Langbehn, D., McCutcheon, V., Nurnberger, J. I., Hesselbrock, M., Porjesz, B., Bierut, L., Marenna, B. C., Cookman, A. & Kuperman, S., Jan 1 2019, In : Alcoholism: Clinical and Experimental Research.

Research output: Contribution to journalArticle

Drinking
Alcohols
Alcohol Drinking
Alcoholism
Medical problems
2016
9 Citations (Scopus)

Transgenerational latent early-life associated regulation unites environment and genetics across generations

Lahiri, D., Maloney, B., Bayon, B. L., Chopra, N., White, F., Greig, N. H. & Nurnberger, J., Mar 1 2016, In : Epigenomics. 8, 3, p. 373-387 15 p.

Research output: Contribution to journalArticle

Environmental Exposure
Epigenomics
Gene Expression
Pregnancy
2019
1 Citation (Scopus)

Exploring the relationship between polygenic risk for cannabis use, peer cannabis use and the longitudinal course of cannabis involvement

Johnson, E. C., Tillman, R., Aliev, F., Meyers, J. L., Salvatore, J. E., Anokhin, A. P., Dick, D. M., Edenberg, H., Kramer, J. R., Kuperman, S., McCutcheon, V. V., Nurnberger, J., Porjesz, B., Schuckit, M. A., Tischfield, J., Bucholz, K. K. & Agrawal, A., Jan 1 2019, (Accepted/In press) In : Addiction.

Research output: Contribution to journalArticle

Cannabis
Odds Ratio
Genome-Wide Association Study
1 Citation (Scopus)

Genome-wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward-related ventral striatum activity in African- and European-Americans

Wetherill, L., Lai, D., Johnson, E. C., Anokhin, A., Bauer, L., Bucholz, K. K., Dick, D. M., Hariri, A. R., Hesselbrock, V., Kamarajan, C., Kramer, J., Kuperman, S., Meyers, J. L., Nurnberger, J., Schuckit, M., Scott, D. M., Taylor, R. E., Tischfield, J., Porjesz, B., Goate, A. M. & 4 others, Edenberg, H., Foroud, T., Bogdan, R. & Agrawal, A., Jan 1 2019, In : Genes, Brain and Behavior. e12580.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Reward
African Americans
Alcoholism
Substance-Related Disorders
2017
85 Citations (Scopus)

Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression

Culverhouse, R. C., Saccone, N. L., Horton, A. C., Ma, Y., Anstey, K. J., Banaschewski, T., Burmeister, M., Cohen-Woods, S., Etain, B., Fisher, H. L., Goldman, N., Guillaume, S., Horwood, J., Juhasz, G., Lester, K. J., Mandelli, L., Middeldorp, C. M., Olié, E., Villafuerte, S., Air, T. M. & 73 others, Araya, R., Bowes, L., Burns, R., Byrne, E. M., Coffey, C., Coventry, W. L., Gawronski, K. A. B., Glei, D., Hatzimanolis, A., Hottenga, J. J., Jaussent, I., Jawahar, C., Jennen-Steinmetz, C., Kramer, J. R., Lajnef, M., Little, K., zu Schwabedissen, H. M., Nauck, M., Nederhof, E., Petschner, P., Peyrot, W. J., Schwahn, C., Sinnamon, G., Stacey, D., Tian, Y., Toben, C., van der Auwera, S., Wainwright, N., Wang, J. C., Willemsen, G., Anderson, I. M., Arolt, V., Åslund, C., Bagdy, G., Baune, B. T., Bellivier, F., Boomsma, D. I., Courtet, P., Dannlowski, U., de Geus, E. J. C., Deakin, J. F. W., Easteal, S., Eley, T., Fergusson, D. M., Goate, A. M., Gonda, X., Grabe, H. J., Holzman, C., Johnson, E. O., Kennedy, M., Laucht, M., Martin, N. G., Munafò, M. R., Nilsson, K. W., Oldehinkel, A. J., Olsson, C. A., Ormel, J., Otte, C., Patton, G. C., Penninx, B. W. J. H., Ritchie, K., Sarchiapone, M., Scheid, J. M., Serretti, A., Smit, J. H., Stefanis, N. C., Surtees, P. G., Völzke, H., Weinstein, M., Whooley, M., Nurnberger, J. I., Breslau, N. & Bierut, L. J., Apr 4 2017, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Meta-Analysis
Genotype
Depression
Alleles
Serotonin Plasma Membrane Transport Proteins
2019
1 Citation (Scopus)

Efficient region-based test strategy uncovers genetic risk factors for functional outcome in bipolar disorder

Budde, M., Friedrichs, S., Alliey-Rodriguez, N., Ament, S., Badner, J. A., Berrettini, W. H., Bloss, C. S., Byerley, W., Cichon, S., Comes, A. L., Coryell, W., Craig, D. W., Degenhardt, F., Edenberg, H., Foroud, T., Forstner, A. J., Frank, J., Gershon, E. S., Goes, F. S., Greenwood, T. A. & 40 others, Guo, Y., Hipolito, M., Hood, L., Keating, B. J., Koller, D. L., Lawson, W. B., Liu, C., Mahon, P. B., McInnis, M. G., McMahon, F. J., Meier, S. M., Mühleisen, T. W., Murray, S. S., Nievergelt, C. M., Nurnberger, J., Nwulia, E. A., Potash, J. B., Quarless, D., Rice, J., Roach, J. C., Scheftner, W. A., Schork, N. J., Shekhtman, T., Shilling, P. D., Smith, E. N., Streit, F., Strohmaier, J., Szelinger, S., Treutlein, J., Witt, S. H., Zandi, P. P., Zhang, P., Zöllner, S., Bickeböller, H., Falkai, P. G., Kelsoe, J. R., Nöthen, M. M., Rietschel, M., Schulze, T. G. & Malzahn, D., Jan 1 2019, In : European Neuropsychopharmacology. 29, 1, p. 156-170 15 p.

Research output: Contribution to journalArticle

Open Access
Bipolar Disorder
Single Nucleotide Polymorphism
Haplotypes
Genes
Chromosomes, Human, Pair 15
2018
1 Citation (Scopus)

Detecting significant genotype–phenotype association rules in bipolar disorder: market research meets complex genetics

Breuer, R., Mattheisen, M., Frank, J., Krumm, B., Treutlein, J., Kassem, L., Strohmaier, J., Herms, S., Mühleisen, T. W., Degenhardt, F., Cichon, S., Nöthen, M. M., Karypis, G., Kelsoe, J., Greenwood, T., Nievergelt, C., Shilling, P., Shekhtman, T., Edenberg, H., Craig, D. & 32 others, Szelinger, S., Nurnberger, J., Gershon, E., Alliey-Rodriguez, N., Zandi, P., Goes, F., Schork, N., Smith, E., Koller, D., Zhang, P., Badner, J., Berrettini, W., Bloss, C., Byerley, W., Coryell, W., Foroud, T., Guo, Y., Hipolito, M., Keating, B., Lawson, W., Liu, C., Mahon, P., McInnis, M., Murray, S., Nwulia, E., Potash, J., Rice, J., Scheftner, W., Zöllner, S., McMahon, F. J., Rietschel, M. & Schulze, T. G., Dec 1 2018, In : International Journal of Bipolar Disorders. 6, 1, 24.

Research output: Contribution to journalArticle

Marketing
Bipolar Disorder
Genome-Wide Association Study
Genetic Research
Data Mining
7 Citations (Scopus)

Genome-wide association study identifies a novel locus for cannabis dependence

Agrawal, A., Chou, Y. L., Carey, C. E., Baranger, D. A. A., Zhang, B., Sherva, R., Wetherill, L., Kapoor, M., Wang, J. C., Bertelsen, S., Anokhin, A. P., Hesselbrock, V., Kramer, J., Lynskey, M. T., Meyers, J. L., Nurnberger, J., Rice, J. P., Tischfield, J., Bierut, L. J., Degenhardt, L. & 16 others, Farrer, L. A., Gelernter, J., Hariri, A. R., Heath, A. C., Kranzler, H. R., Madden, P. A. F., Martin, N. G., Montgomery, G. W., Porjesz, B., Wang, T., Whitfield, J. B., Edenberg, H., Foroud, T., Goate, A. M., Bogdan, R. & Nelson, E. C., May 1 2018, In : Molecular Psychiatry. 23, 5, p. 1293-1302 10 p.

Research output: Contribution to journalArticle

Marijuana Abuse
Genome-Wide Association Study
Cannabis
Genome
Single Nucleotide Polymorphism
2017
16 Citations (Scopus)

Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms

Collaborative Study of the Genetics of Alcoholism Consortium & the German Study of the Genetics of Addiction Consortium, May 2017, In : Alcoholism: Clinical and Experimental Research. 41, 5, p. 911-928 18 p.

Research output: Contribution to journalArticle

Alcoholism
Ethanol
Genes
Alcohols
Long Noncoding RNA
2019
1 Citation (Scopus)

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Wellcome Trust Case-Control Consortium, Cross-Disorder Group of the Psychiatric Genomics Consortium, 23andMe Research Team & Psychosis Endophenotypes International Consortium, Dec 12 2019, In : Cell. 179, 7, p. 1469-1482.e11

Research output: Contribution to journalArticle

Psychiatry
Genes
Tourette Syndrome
Obsessive-Compulsive Disorder
Anorexia Nervosa
2017
89 Citations (Scopus)

Autism genetics: opportunities and challenges for clinical translation

Vorstman, J. A. S., Parr, J. R., Moreno-De-Luca, D., Anney, R. J. L., Nurnberger, J. & Hallmayer, J. F., Mar 6 2017, (Accepted/In press) In : Nature Reviews Genetics.

Research output: Contribution to journalArticle

Autistic Disorder
Genetic Pleiotropy
Penetrance
Protein Biosynthesis
Research
2019

Erratum to: Genome-wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward-related ventral striatum activity in African- and European-Americans (Genes, Brain and Behavior, (e12580), 10.1111/gbb.12580)

Wetherill, L., Lai, D., Johnson, E. C., Anokhin, A., Bauer, L., Bucholz, K. K., Dick, D. M., Hariri, A. R., Hesselbrock, V., Kamarajan, C., Kramer, J., Kuperman, S., Meyers, J. L., Nurnberger, J. I., Schuckit, M., Scott, D. M., Taylor, R. E., Tischfield, J., Porjesz, B., Goate, A. M. & 4 others, Edenberg, H. J., Foroud, T., Bogdan, R. & Agrawal, A., Nov 1 2019, In : Genes, Brain and Behavior. 18, 8, e12608.

Research output: Contribution to journalComment/debate

Open Access
Genome-Wide Association Study
Reward
African Americans
Alcoholism
Substance-Related Disorders
2018

Influence of Parental Alcohol Dependence Symptoms and Parenting on Adolescent Risky Drinking and Conduct Problems: A Family Systems Perspective

Su, J., Kuo, S. I. C., Aliev, F., Guy, M. C., Derlan, C. L., Edenberg, H., Nurnberger, J., Kramer, J. R., Bucholz, K. K., Salvatore, J. E. & Dick, D. M., Jan 1 2018, (Accepted/In press) In : Alcoholism: Clinical and Experimental Research.

Research output: Contribution to journalArticle

Parenting
Alcoholism
Alcohols
Fathers
Mothers
2016
4 Citations (Scopus)

Interactions between alcohol metabolism genes and religious involvement in association with maximum drinks and alcohol dependence symptoms

Chartier, K. G., Dick, D. M., Almasy, L., Chan, G., Aliev, F., Schuckit, M. A., Scott, D. M., Kramer, J., Bucholz, K. K., Bierut, L. J., Nurnberger, J., Porjesz, B. & Hesselbrock, V. M., May 1 2016, In : Journal of Studies on Alcohol and Drugs. 77, 3, p. 393-404 12 p.

Research output: Contribution to journalArticle

Metabolism
Alcoholism
Genes
alcohol
Alcohols
2018
9 Citations (Scopus)

A Biomarker Characterizing Neurodevelopment with applications in Autism

Wu, D., José, J. V., Nurnberger, J. & Torres, E. B., Dec 1 2018, In : Scientific Reports. 8, 1, 614.

Research output: Contribution to journalArticle

Autistic Disorder
Biomarkers
Electromagnetic Phenomena
Coordination Complexes
Neurosciences
2019

Genome-wide association studies of the self-rating of effects of ethanol (SRE)

Lai, D., Wetherill, L., Kapoor, M., Johnson, E. C., Schwandt, M., Ramchandani, V. A., Goldman, D., Joslyn, G., Rao, X., Liu, Y., Farris, S., Mayfield, R. D., Dick, D., Hesselbrock, V., Kramer, J., McCutcheon, V. V., Nurnberger, J., Tischfield, J., Goate, A., Edenberg, H. J. & 4 others, Porjesz, B., Agrawal, A., Foroud, T. & Schuckit, M., Jan 1 2019, In : Addiction Biology. e12800.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Alcoholism
Ethanol
Alcohols
Drinking

Salivary melatonin onset in youth at familial risk for bipolar disorder

Bipolar High Risk Research Group, Apr 1 2019, In : Psychiatry Research. 274, p. 49-57 9 p.

Research output: Contribution to journalArticle

Melatonin
Bipolar Disorder
Light
Polysomnography
Saliva
2016
22 Citations (Scopus)

The Pharmacogenomics of Bipolar Disorder study (PGBD): Identification of genes for lithium response in a prospective sample

Oedegaard, K. J., Alda, M., Anand, A., Andreassen, O. A., Balaraman, Y., Berrettini, W. H., Bhattacharjee, A., Brennand, K. J., Burdick, K. E., Calabrese, J. R., Calkin, C. V., Claasen, A., Coryell, W. H., Craig, D., DeModena, A., Frye, M., Gage, F. H., Gao, K., Garnham, J., Gershon, E. & 18 others, Jakobsen, P., Leckband, S. G., McCarthy, M. J., McInnis, M. G., Maihofer, A. X., Mertens, J., Morken, G., Nievergelt, C. M., Nurnberger, J., Pham, S., Schoeyen, H., Shekhtman, T., Shilling, P. D., Szelinger, S., Tarwater, B., Yao, J., Zandi, P. P. & Kelsoe, J. R., May 5 2016, In : BMC Psychiatry. 16, 1, 129.

Research output: Contribution to journalArticle

Pharmacogenetics
Bipolar Disorder
Lithium
Genes
Genome-Wide Association Study
2019
1 Citation (Scopus)

Patterns and predictors of family environment among adolescents at high and low risk for familial bipolar disorder

Stapp, E. K., Musci, R. J., Fullerton, J. M., Glowinski, A. L., McInnis, M., Mitchell, P. B., Hulvershorn, L., Ghaziuddin, N., Roberts, G. M. P., Merikangas, K. R., Nurnberger, J. & Wilcox, H. C., Jul 1 2019, In : Journal of Psychiatric Research. 114, p. 153-160 8 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Mothers
Interviews
Conflict (Psychology)
Family Relations
2016
4 Citations (Scopus)

CYP2A6 metabolism in the development of smoking behaviors in young adults

Olfson, E., Bloom, J., Bertelsen, S., Budde, J. P., Breslau, N., Brooks, A., Culverhouse, R., Chan, G., Chen, L. S., Chorlian, D., Dick, D. M., Edenberg, H., Hartz, S., Hatsukami, D., Hesselbrock, V. M., Johnson, E. O., Kramer, J. R., Kuperman, S., Meyers, J. L., Nurnberger, J. & 8 others, Porjesz, B., Saccone, N. L., Schuckit, M. A., Stitzel, J., Tischfield, J. A., Rice, J. P., Goate, A. & Bierut, L. J., 2016, (Accepted/In press) In : Addiction Biology.

Research output: Contribution to journalArticle

Tobacco Use Disorder
Cytochrome P-450 Enzyme System
Young Adult
Smoking
Nicotine
2019
7 Citations (Scopus)

Chronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder

McCarthy, M. J., Wei, H., Nievergelt, C. M., Stautland, A., Maihofer, A. X., Welsh, D. K., Shilling, P., Alda, M., Alliey-Rodriguez, N., Anand, A., Andreasson, O. A., Balaraman, Y., Berrettini, W. H., Bertram, H., Brennand, K. J., Calabrese, J. R., Calkin, C. V., Claasen, A., Conroy, C., Coryell, W. H. & 42 others, Craig, D. W., D’Arcangelo, N., Demodena, A., Djurovic, S., Feeder, S., Fisher, C., Frazier, N., Frye, M. A., Gage, F. H., Gao, K., Garnham, J., Gershon, E. S., Glazer, K., Goes, F., Goto, T., Harrington, G., Jakobsen, P., Kamali, M., Karberg, E., Kelly, M., Leckband, S. G., Lohoff, F., McInnis, M. G., Mondimore, F., Morken, G., Nurnberger, J., Obral, S., Oedegaard, K. J., Ortiz, A., Ritchey, M., Ryan, K., Schinagle, M., Schoeyen, H., Schwebel, C., Shaw, M., Shekhtman, T., Slaney, C., Stapp, E., Szelinger, S., Tarwater, B., Zandi, P. P. & Kelsoe, J. R., Feb 1 2019, In : Neuropsychopharmacology. 44, 3, p. 620-628 9 p.

Research output: Contribution to journalArticle

Circadian Rhythm
Bipolar Disorder
Lithium
Therapeutics
Sleep Initiation and Maintenance Disorders