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2018
1 Citation (Scopus)
Alcoholic Liver Diseases
Liver
Substance-Related Disorders
Psychiatry
Liver Diseases
2017

Editorial: treating the liver to treat the kidney in non-alcoholic steatohepatitis – authors' reply

Vilar-Gomez, E. & Chalasani, N., Feb 1 2017, In : Alimentary Pharmacology and Therapeutics. 45, 4, p. 566-567 2 p.

Research output: Contribution to journalEditorial

Fatty Liver
Kidney
Liver
11 Citations (Scopus)
Cysteamine
Phase II Clinical Trials
Unsaturated Fatty Acids
Histology
Randomized Controlled Trials
61 Citations (Scopus)

Non-invasive assessment of non-alcoholic fatty liver disease: Clinical prediction rules and blood-based biomarkers

Vilar-Gomez, E. & Chalasani, N., Jan 1 2017, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

Decision Support Techniques
Biomarkers
Fatty Liver
Fibrosis
Liver Cirrhosis
6 Citations (Scopus)

Molecular mechanisms of nonalcoholic fatty liver disease: Potential role for 12-lipoxygenase

Samala, N., Tersey, S. A., Chalasani, N., Anderson, R. M. & Mirmira, R., 2017, (Accepted/In press) In : Journal of Diabetes and its Complications.

Research output: Contribution to journalArticle

Arachidonate 12-Lipoxygenase
Insulin Resistance
Lipoxygenases
Endoplasmic Reticulum Stress
Linoleic Acid
2019
2 Citations (Scopus)
Biomarkers
Fatty Liver
Liver
Serum
Pharmaceutical Preparations
2018

In a pilot study, reduced fatty acid desaturase 1 function was associated with nonalcoholic fatty liver disease and response to treatment in children

Nobili, V., Alisi, A., Liu, Z., Liang, T., Crudele, A., Raponi, M., Lin, J., Chalasani, N. & Liu, W., Jan 1 2018, (Accepted/In press) In : Pediatric Research.

Research output: Contribution to journalArticle

Fatty Acid Desaturases
Docosahexaenoic Acids
Choline
Alleles
Vitamin E
2019

Development and Validation of a Model to Predict Acute Kidney Injury in Hospitalized Patients With Cirrhosis

Patidar, K. R., Xu, C., Shamseddeen, H., Cheng, Y. W., Ghabril, M. S., Mukthinuthalapati, V. V. P. K., Fricker, Z. P., Akinyeye, S., Nephew, L. D., Desai, A. P., Anderson, M., El-Achkar, T. M., Chalasani, N. P. & Orman, E. S., Sep 1 2019, In : Clinical and translational gastroenterology. 10, 9, p. e00075

Research output: Contribution to journalArticle

Open Access
Acute Kidney Injury
Fibrosis
End Stage Liver Disease
International Normalized Ratio
Leukocyte Count
2017

Laboratory tests in liver disease

Vuppalanchi, R. & Chalasani, N., Mar 31 2017, Practical Hepatic Pathology: A Diagnostic Approach: Second Edition. Elsevier, p. 43-53 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Liver Diseases
2019
1 Citation (Scopus)

Trends in Characteristics, Mortality, and Other Outcomes of Patients with Newly Diagnosed Cirrhosis

Orman, E., Roberts, A., Ghabril, M., Nephew, L., Desai, A., Patidar, K. & Chalasani, N., Jan 1 2019, In : JAMA Network Open.

Research output: Contribution to journalArticle

Open Access
Fibrosis
Mortality
Alcoholic Liver Cirrhosis
Hepatitis
Hepatocellular Carcinoma
2017
6 Citations (Scopus)

Perilipin Staining Distinguishes Between Steatosis and Nonalcoholic Steatohepatitis in Adults and Children

Carr, R. M., Dhir, R., Mahadev, K., Comerford, M., Chalasani, N. & Ahima, R. S., Jan 1 2017, In : Clinical Gastroenterology and Hepatology. 15, 1, p. 145-147 3 p.

Research output: Contribution to journalShort survey

Staining and Labeling
Non-alcoholic Fatty Liver Disease
Perilipin-1
2019

Letter: metformin treatment and hepatocellular carcinoma risk in non-alcoholic fatty liver disease. Authors' reply

Vilar-Gomez, E. & Chalasani, N., Oct 1 2019, In : Alimentary pharmacology & therapeutics. 50, 7, p. 836-837 2 p.

Research output: Contribution to journalLetter

Metformin
Hepatocellular Carcinoma
Non-alcoholic Fatty Liver Disease
2017
5 Citations (Scopus)

Risk factors for hepatocellular carcinoma in cirrhosis due to nonalcoholic fatty liver disease: A multicenter, case-control study

Corey, K. E., Gawrieh, S., deLemos, A. S., Zheng, H., Scanga, A. E., Haglund, J. W., Sanchez, J., Danford, C. J., Comerford, M., Bossi, K., Munir, S., Chalasani, N. & Wattacheril, J., 2017, In : World Journal of Hepatology. 9, 7, p. 385-390 6 p.

Research output: Contribution to journalArticle

Case-Control Studies
Hepatocellular Carcinoma
Fibrosis
Transplants
Non-alcoholic Fatty Liver Disease
2019
4 Citations (Scopus)
Chemical and Drug Induced Liver Injury
Liver Diseases
Chronic Disease
Prescriptions
Non-alcoholic Fatty Liver Disease
2016
11 Citations (Scopus)

Febuxostat-induced acute liver injury

Bohm, M., Vuppalanchi, R. & Chalasani, N., 2016, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Gout Suppressants
Chemical and Drug Induced Liver Injury
Liver
Wounds and Injuries
Febuxostat
2017
1 Citation (Scopus)

Causality Assessment for Suspected Drug-Induced Liver Injury in Patients With Underlying Chronic Liver Disease

Dakhoul, L. & Chalasani, N., Mar 1 2017, In : Clinical Liver Disease. 9, 3, p. 63-65 3 p.

Research output: Contribution to journalReview article

Chemical and Drug Induced Liver Injury
Causality
Liver Diseases
Chronic Disease
12 Citations (Scopus)
Sleep
Fibrosis
Quality of Life
Muscle Cramp
Actigraphy
2018
3 Citations (Scopus)

Drug-induced chronic liver injury

Dakhoul, L., Ghabril, M. & Chalasani, N., Jan 1 2018, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

Chronic Drug-Induced Liver Injury
2017
2 Citations (Scopus)
HMGB1 Protein
fatty liver
Liver
pioglitazone
Serum
2019
9 Citations (Scopus)
Vitamin E
Fibrosis
Transplants
Survival
Liver
2018
1 Citation (Scopus)

Automated assessment of steatosis in murine fatty liver

Sethunath, D., Morusu, S., Tuceryan, M., Cummings, O., Zhang, H., Yin, X-M., Vanderbeck, S., Chalasani, N. & Gawrieh, S., May 1 2018, In : PLoS One. 13, 5, e0197242.

Research output: Contribution to journalArticle

fatty liver
Fatty Liver
Liver
Liver Diseases
liver diseases
2020

Spontaneous Fluctuations in Liver Biochemistries in Patients with Compensated NASH Cirrhosis: Implications for Drug Hepatotoxicity Monitoring

Shamseddeen, H., Vilar-Gomez, E., Chalasani, N., Myers, R. P., Subramanian, G. M., Shlevin, H. H., Allgood, A. E. & Orman, E. S., Jan 1 2020, (Accepted/In press) In : Drug Safety.

Research output: Contribution to journalArticle

Biochemistry
Drug Monitoring
Liver
Alanine Transaminase
Fibrosis
2016
22 Citations (Scopus)

Child-Turcotte-Pugh Class is Best at Stratifying Risk in Variceal Hemorrhage: Analysis of a US Multicenter Prospective Study

for the Vapreotide Study Group, Oct 24 2016, (Accepted/In press) In : Journal of Clinical Gastroenterology.

Research output: Contribution to journalArticle

End Stage Liver Disease
Multicenter Studies
Prospective Studies
Hemorrhage
Mortality
Liver Neoplasms
MicroRNAs
Fibrosis
Liver
Non-alcoholic Fatty Liver Disease
2017
34 Citations (Scopus)

Treatment with LY2409021, a glucagon receptor antagonist, increases liver fat in patients with type 2 diabetes

Guzman, C. B., Zhang, X. M., Liu, R., Regev, A., Shankar, S., Garhyan, P., Pillai, S. G., Kazda, C., Chalasani, N. & Hardy, T. A., 2017, (Accepted/In press) In : Diabetes, Obesity and Metabolism.

Research output: Contribution to journalArticle

Glucagon Receptors
Type 2 Diabetes Mellitus
Fats
Liver
Placebos
2020

Non-selective beta blocker use is associated with improved short-term survival in patients with cirrhosis referred for liver transplantation

Ngwa, T., Orman, E., Gomez, E. V., Vuppalanchi, R., Kubal, C., Chalasani, N. & Ghabril, M., Jan 6 2020, In : BMC Gastroenterology. 20, 1, 4.

Research output: Contribution to journalArticle

Open Access
Liver Transplantation
Fibrosis
Survival
Acute Kidney Injury
Mortality
2019
1 Citation (Scopus)

Histologic Findings of Advanced Fibrosis and Cirrhosis in Patients With Nonalcoholic Fatty Liver Disease Who Have Normal Aminotransferase Levels

and the NASH Clinical Research Network, Oct 1 2019, In : The American journal of gastroenterology. 114, 10, p. 1626-1635 10 p.

Research output: Contribution to journalArticle

Transaminases
Fibrosis
Aspartate Aminotransferases
Alanine Transaminase
Histology
2016
27 Citations (Scopus)

Nonalcoholic Fatty Liver Disease in Latinos

Saab, S., Manne, V., Nieto, J., Schwimmer, J. B. & Chalasani, N., Jan 1 2016, In : Clinical Gastroenterology and Hepatology. 14, 1, p. 5-12 8 p.

Research output: Contribution to journalArticle

Hispanic Americans
Population
Patient Acceptance of Health Care
Health Services Accessibility
Non-alcoholic Fatty Liver Disease
2018
1 Citation (Scopus)

Haptoglobin 2 Allele is Associated With Histologic Response to Vitamin E in Subjects With Nonalcoholic Steatohepatitis

for the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN), Jan 1 2018, (Accepted/In press) In : Journal of Clinical Gastroenterology.

Research output: Contribution to journalArticle

Haptoglobins
Vitamin E
Alleles
Genotype
Placebos
2019
1 Citation (Scopus)

Importance of Hepatitis C Virus RNA Testing in Patients with Suspected Drug-Induced Liver Injury

Ahmad, J., Reddy, K. R., Tillmann, H. L., Hayashi, P. H., Chalasani, N., Fontana, R. J., Navarro, V. J., Stolz, A., Barnhart, H., Cloherty, G. A. & Hoofnagle, J. H., Jan 1 2019, In : Digestive Diseases and Sciences.

Research output: Contribution to journalArticle

Chemical and Drug Induced Liver Injury
Hepacivirus
RNA
Wounds and Injuries
Expert Testimony

Increasing Economic Burden in Hospitalized Patients With Cirrhosis: Analysis of a National Database

Desai, A. P., Mohan, P., Nokes, B., Sheth, D., Knapp, S., Boustani, M., Chalasani, N., Fallon, M. B. & Calhoun, E. A., Jul 1 2019, In : Clinical and translational gastroenterology. 10, 7, p. e00062

Research output: Contribution to journalArticle

Open Access
Fibrosis
Economics
Databases
Costs and Cost Analysis
Inpatients
6 Citations (Scopus)
Open Access
Cholestasis
Wounds and Injuries
Testosterone Congeners
Liver
Controlled Substances
4 Citations (Scopus)

Relationship between resolution of non-alcoholic steatohepatitis and changes in lipoprotein sub-fractions: a post-hoc analysis of the PIVENS trial

the NASH Clinical Research Network, May 1 2019, In : Alimentary Pharmacology and Therapeutics. 49, 9, p. 1205-1213 9 p.

Research output: Contribution to journalArticle

Open Access
Fatty Liver
Lipoproteins
pioglitazone
E-Selectin
Vitamin E
2017
14 Citations (Scopus)

Azathioprine and 6-Mercaptopurine-induced Liver Injury

DILIN Investigators, 2017, In : Journal of Clinical Gastroenterology. 51, 1, p. 63-69 7 p.

Research output: Contribution to journalArticle

6-Mercaptopurine
Azathioprine
Liver
Wounds and Injuries
Hepatitis
46 Citations (Scopus)

Features of Autoimmune Hepatitis in Patients With Drug-induced Liver Injury

de Boer, Y. S., Kosinski, A. S., Urban, T. J., Zhao, Z., Long, N., Chalasani, N., Kleiner, D. E. & Hoofnagle, J. H., Jan 1 2017, In : Clinical Gastroenterology and Hepatology. 15, 1, p. 103-112.e2

Research output: Contribution to journalArticle

Chemical and Drug Induced Liver Injury
Autoimmune Hepatitis
Nitrofurantoin
Methyldopa
Hydralazine
2018
23 Citations (Scopus)

The circulating microbiome signature and inferred functional metagenomics in alcoholic hepatitis

Puri, P., Liangpunsakul, S., Christensen, J. E., Shah, V. H., Kamath, P. S., Gores, G. J., Walker, S., Comerford, M., Katz, B., Borst, A., Yu, A., Kumar, D. P., Mirshahi, F., Radaeva, S., Chalasani, N., Crabb, D. & Sanyal, A. J., Jan 1 2018, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Alcoholic Hepatitis
Metagenomics
Microbiota
Drinking
Fusobacteria
2016
91 Citations (Scopus)

Standard Definitions and Common Data Elements for Clinical Trials in Patients with Alcoholic Hepatitis: Recommendation from the NIAAA Alcoholic Hepatitis Consortia

Crabb, D., Bataller, R., Chalasani, N., Kamath, P. S., Lucey, M., Mathurin, P., McClain, C., McCullough, A., Mitchell, M. K. C., Morgan, T. R., Nagy, L., Radaeva, S., Sanyal, A., Shah, V. & Szabo, G., Apr 1 2016, In : Gastroenterology. 150, 4, p. 785-790 6 p.

Research output: Contribution to journalArticle

Severity of Illness Index
National Institute on Alcohol Abuse and Alcoholism (U.S.)
Endpoint Determination
Alcoholic Hepatitis
Research Design
2019

Admission plasma uromodulin and the risk of acute kidney injury in hospitalized patients with cirrhosis: a pilot study

Patidar, K. R., Garimella, P. S., Macedo, E., Slaven, J. E., Ghabril, M. S., Weber, R. E., Anderson, M., Orman, E. S., Nephew, L. D., Desai, A. P., Chalasani, N. P. & El-Achkar, T. M., Oct 1 2019, In : American journal of physiology. Gastrointestinal and liver physiology. 317, 4, p. G447-G452

Research output: Contribution to journalArticle

Uromodulin
Acute Kidney Injury
Fibrosis
Creatinine
Urine
2017
27 Citations (Scopus)

Death and liver transplantation within 2 years of onset of drug-induced liver injury

Hayashi, P. H., Rockey, D. C., Fontana, R. J., Tillmann, H. L., Kaplowitz, N., Barnhart, H. X., Gu, J., Chalasani, N., Reddy, K. R., Sherker, A. H. & Hoofnagle, J. H., 2017, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Chemical and Drug Induced Liver Injury
Liver Transplantation
Cause of Death
Confidence Intervals
Fatal Outcome
2019
5 Citations (Scopus)

Oxidized Derivatives of Linoleic Acid in Pediatric Metabolic Syndrome: Is Their Pathogenic Role Modulated by the Genetic Background and the Gut Microbiota?

Tricò, D., Di Sessa, A., Caprio, S., Chalasani, N., Liu, W., Liang, T., Graf, J., Herzog, R. I., Johnson, C. D., Umano, G. R., Feldstein, A. E. & Santoro, N., Jan 10 2019, In : Antioxidants and Redox Signaling. 30, 2, p. 241-250 10 p.

Research output: Contribution to journalArticle

Pediatrics
Linoleic Acid
Metabolites
Derivatives
Fatty Acid Desaturases
2017
8 Citations (Scopus)

Alcohol abstinence ameliorates the dysregulated immune profiles in patients with alcoholic hepatitis: A prospective observational study

Li, W., Amet, T., Xing, Y., Yang, D., Liangpunsakul, S., Puri, P., Kamath, P. S., Sanyal, A. J., Shah, V. H., Katz, B., Radaeva, S., Crabb, D., Chalasani, N. & Yu, A., Aug 1 2017, In : Hepatology. 66, 2, p. 575-590 16 p.

Research output: Contribution to journalArticle

Alcohol Abstinence
Alcoholic Hepatitis
Observational Studies
Prospective Studies
Chemokine CCL22
2019

Early predictors of outcomes of hospitalization for cirrhosis and assessment of the impact of race and ethnicity at safety-net hospitals

Mukthinuthalapati, V. V. P. K., Akinyeye, S., Fricker, Z. P., Syed, M., Orman, E., Nephew, L., Vilar-Gomez, E., Slaven, J., Chalasani, N., Balakrishnan, M., Long, M. T., Attar, B. M. & Ghabril, M., Mar 1 2019, In : PLoS ONE. 14, 3, e0211811.

Research output: Contribution to journalArticle

Open Access
Safety-net Providers
nationalities and ethnic groups
Hospitalization
Fibrosis
Liver
2018
1 Citation (Scopus)

Loci-specific differences in blood DNA methylation in HBV-negative populations at risk for hepatocellular carcinoma development

Lubecka, K., Flower, K., Beetch, M., Qiu, J., Kurzava, L., Buvala, H., Ruhayel, A., Gawrieh, S., Liangpunsakul, S., Gonzalez, T., McCabe, G., Chalasani, N., Flanagan, J. M. & Stefanska, B., Jan 1 2018, (Accepted/In press) In : Epigenetics.

Research output: Contribution to journalArticle

DNA Methylation
Hepatocellular Carcinoma
Neoplasms
Nucleic Acid Regulatory Sequences
Delayed Diagnosis
2016
5 Citations (Scopus)

Increased parenchymal damage and steatohepatitis in Caucasian non-alcoholic fatty liver disease patients with common IL1B and IL6 polymorphisms

the NASH Clinical Research Network, Dec 1 2016, In : Alimentary Pharmacology and Therapeutics. 44, 11-12, p. 1253-1264 12 p.

Research output: Contribution to journalArticle

Fatty Liver
Interleukin-6
Mallory Bodies
Fibrosis
Alleles
2020

Alcohol Rehabilitation Within 30 Days of Hospital Discharge Is Associated With Reduced Readmission, Relapse, and Death in Patients With Alcoholic Hepatitis

Peeraphatdit, T. B., Kamath, P. S., Karpyak, V. M., Davis, B., Desai, V., Liangpunsakul, S., Sanyal, A., Chalasani, N., Shah, V. H. & Simonetto, D. A., Feb 2020, In : Clinical Gastroenterology and Hepatology. 18, 2, p. 477-485.e5

Research output: Contribution to journalArticle

Alcoholic Hepatitis
Rehabilitation
Alcohols
Recurrence
Odds Ratio
2019
Open Access
Aspirin
Fibrosis
Pharmaceutical Preparations
Non-alcoholic Fatty Liver Disease
2018
9 Citations (Scopus)

Liver Stiffness Measurements in Patients with Noncirrhotic Portal Hypertension—The Devil Is in the Details

Vuppalanchi, R., Mathur, K., Pyko, M., Samala, N. & Chalasani, N., Jan 1 2018, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Portal Hypertension
Liver
Fibrosis
Elasticity Imaging Techniques
Portal Vein
2016
42 Citations (Scopus)
Portal Vein
Liver Transplantation
Thrombosis
Tissue and Organ Procurement
Graft Survival
2019
5 Citations (Scopus)
Lipids
Liver
Wounds and Injuries
Fibrosis
Non-alcoholic Fatty Liver Disease
7 Citations (Scopus)
Metformin
Fatty Liver
Fibrosis
Hepatocellular Carcinoma
Transplants