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2017
1 Citation (Scopus)

Transthyretin amyloidosis: a little history of hereditary amyloidosis

Benson, M., Mar 16 2017, In : Amyloid. 24, p. 76-77 2 p.

Research output: Contribution to journalLetter

Familial Amyloidosis
Amyloidosis, Hereditary, Transthyretin-Related
2016
2 Citations (Scopus)

Liver transplant alone without kidney transplant for fibrinogen Aα-chain (AFib) renal amyloidosis

Fix, O. K., Stock, P. G., Lee, B. K. & Benson, M., Mar 10 2016, (Accepted/In press) In : Amyloid. p. 1-2 2 p.

Research output: Contribution to journalArticle

2019
3 Citations (Scopus)

A pair of peptides inhibits seeding of the hormone transporter transthyretin into amyloid fibrils

Saelices, L., Nguyen, B. A., Chung, K., Wang, Y., Ortega, A., Lee, J. H., Coelho, T., Bijzet, J., Benson, M. & Eisenberg, D. S., Jan 1 2019, In : Journal of Biological Chemistry. 294, 15, p. 6130-6141 12 p.

Research output: Contribution to journalArticle

Open Access
Prealbumin
Amyloid
Hormones
Peptides
Familial Amyloidosis

Treatment of ATTR cardiomyopathy with a TTR specific antisense oligonucleotide, inotersen

Dasgupta, N. R. & Benson, M. D., Mar 29 2019, In : Amyloid. 26, sup1, p. 20-21 2 p.

Research output: Contribution to journalLetter

Antisense Oligonucleotides
Cardiomyopathies
2017
21 Citations (Scopus)

Safety and efficacy of a TTR specific antisense oligonucleotide in patients with transthyretin amyloid cardiomyopathy

Benson, M., Dasgupta, N., Rissing, S., Smith, J. & Feigenbaum, H., Sep 13 2017, (Accepted/In press) In : Amyloid. p. 1-7 7 p.

Research output: Contribution to journalArticle

Prealbumin
Antisense Oligonucleotides
Cardiomyopathies
Amyloid
Safety

An aggressive form of transthyretin amyloidosis

Dasgupta, N., Wang, A. K., Hardwick, J. & Benson, M., Mar 16 2017, In : Amyloid. 24, p. 95-96 2 p.

Research output: Contribution to journalLetter

Amyloidosis, Hereditary, Transthyretin-Related

Familial wild-type transthyretin cardiomyopathy

Benson, M., Berk, J. L., Connors, L. H. & Dasgupta, N., Mar 16 2017, In : Amyloid. 24, p. 91-92 2 p.

Research output: Contribution to journalLetter

Prealbumin
Cardiomyopathies

Insulin: a diagnostic warning

Liepnieks, J. J., Benson, M. & Kluve-Beckerman, B., Mar 16 2017, In : Amyloid. 24, p. 159-160 2 p.

Research output: Contribution to journalLetter

Insulin
2019

A transgenic mouse model reproduces human hereditary systemic amyloidosis

Chabert, M., Rousset, X., Colombat, M., Lacasa, M., Kakanakou, H., Bourderioux, M., Brousset, P., Burlet-Schiltz, O., Liepnieks, J. J., Kluve-Beckerman, B., Lambert, G., Châtelet, F. P., Benson, M. & Kalopissis, A. D., Jan 1 2019, In : Kidney international.

Research output: Contribution to journalArticle

Familial Amyloidosis
Transgenic Mice
Amyloidosis
Amyloid
Amyloidogenic Proteins
2018
6 Citations (Scopus)

Amyloid seeding of transthyretin by ex vivo cardiac fibrils and its inhibition

Saelices, L., Chung, K., Lee, J. H., Cohn, W., Whitelegge, J. P., Benson, M. & Eisenberg, D. S., Jul 17 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 29, p. E6741-E6750

Research output: Contribution to journalArticle

Prealbumin
Amyloid
Seeds
Protein Precursors
Liver
2020

Editorial Commentary: Advances in transthyretin amyloid cardiomyopathy

Benson, M. D. & Dasgupta, N. R., Jan 1 2020, (Accepted/In press) In : Trends in Cardiovascular Medicine.

Research output: Contribution to journalEditorial

2018
5 Citations (Scopus)

Hereditary transthyretin amyloidosis: baseline characteristics of patients in the NEURO-TTR trial

Waddington-Cruz, M., Ackermann, E. J., Polydefkis, M., Heitner, S. B., Dyck, P. J., Barroso, F. A., Wang, A. K., Berk, J. L., Dyck, P. J. B., Monia, B. P., Hughes, S. G., Tai, L., Jesse Kwoh, T., Jung, S. W., Coelho, T., Benson, M. & Gertz, M. A., Jan 1 2018, (Accepted/In press) In : Amyloid.

Research output: Contribution to journalArticle

Familial Amyloidosis
Amyloidosis
Polyneuropathies
Quality of Life
Cardiomyopathies
2019

Inotersen preserves or improves quality of life in hereditary transthyretin amyloidosis

Coelho, T., Yarlas, A., Waddington-Cruz, M., White, M. K., Sikora Kessler, A., Lovley, A., Pollock, M., Guthrie, S., Ackermann, E. J., Hughes, S. G., Karam, C., Khella, S., Gertz, M., Merlini, G., Obici, L., Schmidt, H. H., Polydefkis, M., Dyck, P. J. B., Brannagan, T. H., Conceição, I. & 2 others, Benson, M. D. & Berk, J. L., Jan 1 2019, (Accepted/In press) In : Journal of Neurology.

Research output: Contribution to journalArticle

Open Access
Familial Amyloidosis
Quality of Life
Placebos
Polyneuropathies
Diabetic Neuropathies
2017
22 Citations (Scopus)

Assessing mNIS+7Ionis and international neurologists' proficiency in a familial amyloidotic polyneuropathy trial

Dyck, P. J., Kincaid, J., Dyck, P. J. B., Chaudhry, V., Goyal, N. A., Alves, C., Salhi, H., Wiesman, J. F., Labeyrie, C., Robinson-Papp, J., Cardoso, M., Laura, M., Ruzhansky, K., Cortese, A., Brannagan, T. H., Khoury, J., Khella, S., Waddington-cruz, M., Ferreira, J., Wang, A. K. & 24 others, Pinto, M. V., Ayache, S. S., Benson, M., Berk, J. L., Coelho, T., Polydefkis, M., Gorevic, P., Adams, D. H., Plante-Bordeneuve, V., Whelan, C., Merlini, G., Heitner, S., Drachman, B. M., Conceição, I., Klein, C. J., Gertz, M. A., Ackermann, E. J., Hughes, S. G., Mauermann, M. L., Bergemann, R., Lodermeier, K. A., Davies, J. L., Carter, R. E. & Litchy, W. J., 2017, (Accepted/In press) In : Muscle and Nerve.

Research output: Contribution to journalArticle

Polyneuropathies
Health
Neurophysiology
Neurologic Manifestations
Oligonucleotides

AA cardiomyopathy

Dasgupta, N., Cummings, O., Phillips, C. & Benson, M., Mar 16 2017, In : Amyloid. 24, p. 138-139 2 p.

Research output: Contribution to journalLetter

Cardiomyopathies
2019
5 Citations (Scopus)

Inotersen (transthyretin-specific antisense oligonucleotide) for treatment of transthyretin amyloidosis

Benson, M., Dasgupta, N. & Monia, B. P., Feb 1 2019, In : Neurodegenerative disease management. 9, 1, p. 25-30 6 p.

Research output: Contribution to journalArticle

Prealbumin
Antisense Oligonucleotides
Peripheral Nervous System Diseases
Familial Amyloidosis
Quality of Life
2016
3 Citations (Scopus)

Amyloid Cardiomyopathy

Benson, M. & Dasgupta, N., Jul 5 2016, In : Journal of the American College of Cardiology. 68, 1, p. 25-28 4 p.

Research output: Contribution to journalComment/debate

Prealbumin
Amyloidosis
Cardiomyopathies
Amyloid
Immunohistochemistry
49 Citations (Scopus)

Suppressing transthyretin production in mice, monkeys and humans using 2nd-Generation antisense oligonucleotides

Ackermann, E. J., Guo, S., Benson, M., Booten, S., Freier, S., Hughes, S. G., Kim, T. W., Jesse Kwoh, T., Matson, J., Norris, D., Yu, R., Watt, A. & Monia, B. P., Jun 17 2016, (Accepted/In press) In : Amyloid. p. 1-10 10 p.

Research output: Contribution to journalArticle

Prealbumin
Antisense Oligonucleotides
Haplorhini
Amyloidosis
Blood Proteins
2019

Inotersen treatment for ATTR amyloidosis

Benson, M., Mar 29 2019, In : Amyloid. 26, sup1, p. 27-28 2 p.

Research output: Contribution to journalLetter

Amyloidosis
2017
7 Citations (Scopus)

Treatment of transthyretin cardiomyopathy with a TTR-specific antisense oligonucleotide (IONIS-TTRRx)

Benson, M., Ackermann, E. J. & Monia, B. P., Mar 16 2017, In : Amyloid. 24, p. 134-135 2 p.

Research output: Contribution to journalLetter

Amyloid Neuropathies
Familial Amyloid Neuropathies
Prealbumin
Antisense Oligonucleotides
Cardiomyopathies
2019

ALECT2 and NASH

Cummings, O., Dasgupta, N. & Benson, M., Mar 29 2019, In : Amyloid. 26, sup1, p. 158-159 2 p.

Research output: Contribution to journalLetter

2016
210 Citations (Scopus)

Amyloid fibril proteins and amyloidosis: chemical identification and clinical classification International Society of Amyloidosis 2016 Nomenclature Guidelines

Sipe, J. D., Benson, M., Buxbaum, J. N., Ikeda, S. I., Merlini, G., Saraiva, M. J. M. & Westermark, P., Oct 1 2016, In : Amyloid. 23, 4, p. 209-213 5 p.

Research output: Contribution to journalArticle

Amyloidogenic Proteins
Amyloidosis
Amyloid
Terminology
Guidelines
3 Citations (Scopus)

Carbamylation of the amino-terminal residue (Gly1) of mouse serum amyloid A promotes amyloid formation in a cell culture model

Kluve-Beckerman, B., Liepnieks, J. J., Benson, M., Lai, X., Qi, G. & Wang, M., Dec 1 2016, In : FEBS Letters. 590, 23, p. 4296-4307 12 p.

Research output: Contribution to journalLetter

Serum Amyloid A Protein
Cell culture
Amyloid
Cell Culture Techniques
Amyloidosis
2 Citations (Scopus)

Disease-free survival following high dose or standard dose therapy in patients with amyloidosis

Kiel, P. J., Trueg, A. O., Ferguson, M., Benson, M. & Abonour, R., Jul 1 2016, In : British Journal of Haematology. 174, 1, p. 153-155 3 p.

Research output: Contribution to journalLetter

Melphalan
Amyloidosis
Disease-Free Survival
Therapeutics
Bortezomib
2018
51 Citations (Scopus)

Amyloid nomenclature 2018: recommendations by the International Society of Amyloidosis (ISA) nomenclature committee

Benson, M., Buxbaum, J. N., Eisenberg, D. S., Merlini, G., Saraiva, M. J. M., Sekijima, Y., Sipe, J. D. & Westermark, P., Jan 1 2018, (Accepted/In press) In : Amyloid.

Research output: Contribution to journalArticle

Amyloidosis
Amyloid
Terminology
Serum Amyloid P-Component
Birefringence
2016
1 Citation (Scopus)

Biochemical characterization of vitreous amyloid formed after liver transplantation

Liepnieks, J. J., Phan, A-D., Wise, R. J., Hrisomalos, F. N. & Benson, M., Apr 1 2016, (Accepted/In press) In : Amyloid. p. 1-2 2 p.

Research output: Contribution to journalArticle

Familial Amyloid Neuropathies
Amyloidogenic Proteins
Vitreous Body
Prealbumin
Retinal Pigment Epithelium
2019

Inotersen therapy of transthyretin amyloid cardiomyopathy

Dasgupta, N. R., Rissing, S. M., Smith, J., Jung, J. & Benson, M. D., Jan 1 2019, (Accepted/In press) In : Amyloid.

Research output: Contribution to journalArticle

Prealbumin
Cardiomyopathies
Amyloid
Therapeutics
Safety
2018
199 Citations (Scopus)

Inotersen treatment for patients with Hereditary transthyretin amyloidosis

Benson, M., Waddington-Cruz, M., Berk, J. L., Polydefkis, M., Dyck, P. J., Wang, A. K., Planté-Bordeneuve, V., Barroso, F. A., Merlini, G., Obici, L., Scheinberg, M., Brannagan, T. H., Litchy, W. J., Whelan, C., Drachman, B. M., Adams, D., Heitner, S. B., Conceição, I., Schmidt, H. H., Vita, G. & 15 others, Campistol, J. M., Gamez, J., Gorevic, P. D., Gane, E., Shah, A. M., Solomon, S. D., Monia, B. P., Hughes, S. G., Jesse Kwoh, T., McEvoy, B. W., Jung, S. W., Baker, B. F., Ackermann, E. J., Gertz, M. A. & Coelho, T., Jul 5 2018, In : New England Journal of Medicine. 379, 1, p. 22-31 10 p.

Research output: Contribution to journalArticle

Familial Amyloidosis
Prealbumin
Placebos
Quality of Life
Therapeutics
2019

A cell-based high-throughput screening method to directly examine transthyretin amyloid fibril formation at neutral pH

Ueda, M., Okada, M., Mizuguchi, M., Kluve-Beckerman, B., Kanenawa, K., Isoguchi, A., Misumi, Y., Tasaki, M., Ueda, A., Kanai, A., Sasaki, R., Masuda, T., Inoue, Y., Nomura, T., Shinriki, S., Shuto, X. T., Kai, H., Yamashita, T., Matsui, H., Benson, M. & 1 others, Ando, Y., Jan 1 2019, In : Journal of Biological Chemistry. 294, 29, p. 11259-11275 17 p.

Research output: Contribution to journalArticle

Open Access
High-Throughput Screening Assays
Prealbumin
Amyloid
Screening
Throughput