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  • Andrew Saykin
2017

Characterizing gene and protein crosstalks in subjects at risk of developing Alzheimer's disease: A new computational approach

for the Alzheimer's Disease Neuroimaging Initiative, Sep 1 2017, In : Processes. 5, 3, 47.

Research output: Contribution to journalArticle

1 Scopus citations

Cognitive complaints in older adults at risk for Alzheimer's disease are associated with altered resting-state networks

Contreras, J. A., Goñi, J., Risacher, S. L., Amico, E., Yoder, K., Dzemidzic, M., West, J. D., McDonald, B. C., Farlow, M. R., Sporns, O. & Saykin, A. J., 2017, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 6, p. 40-49 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Effects of traumatic brain injury and posttraumatic stress disorder on development of Alzheimer's disease in Vietnam Veterans using the Alzheimer's Disease Neuroimaging Initiative: Preliminary report

Weiner, M., Harvey, D., Hayes, J., Landau, S., Aisen, P., Petersen, R., Tosun, D., Veitch, D., Jack, C., Decarli, C., Saykin, A., Grafman, J. & Neylan, T., Jun 1 2017, In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 3, 2, p. 177-188 12 p.

Research output: Contribution to journalArticle

23 Scopus citations

Genome-wide association and interaction studies of CSF T-tau/Aβ42 ratio in ADNI cohort

Li, J., Zhang, Q., Chen, F., Meng, X., Liu, W., Chen, D., Yan, J., Kim, S., Wang, L., Feng, W., Saykin, A. J., Liang, H. & Shen, L., Sep 2017, In : Neurobiology of Aging. 57, p. 247.e1-247.e8

Research output: Contribution to journalArticle

11 Scopus citations

Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers

Alzheimer’s Disease Neuroimaging Initiative (ADNI) & The Alzheimer Disease Genetic Consortium (ADGC), May 1 2017, In : Acta Neuropathologica. 133, 5, p. 839-856 18 p.

Research output: Contribution to journalArticle

38 Scopus citations

Genome-wide association study of language performance in Alzheimer's disease

The Alzheimer's Disease Neuroimaging Initiative, Sep 2017, In : Brain and Language. 172, p. 22-29 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Genome-wide network-based pathway analysis of CSF t-tau/Aβ1-42 ratio in the ADNI cohort

for the Alzheimer's Disease Neuroimaging Initiative, May 30 2017, In : BMC genomics. 18, 1, 421.

Research output: Contribution to journalArticle

6 Scopus citations

Identification of associations between genotypes and longitudinal phenotypes via temporally-constrained group sparse canonical correlation analysis

Hao, X., Li, C., Yan, J., Yao, X., Risacher, S. L., Saykin, A. J., Shen, L. & Zhang, D., Jul 15 2017, In : Bioinformatics. 33, 14, p. i341-i349

Research output: Contribution to journalArticle

7 Scopus citations

Identification of discriminative imaging proteomics associations in Alzheimer’s disease via a novel sparse correlation model

Alzheimer's Disease Neuroimaging Initiative, Jan 1 2017, In : Pacific Symposium on Biocomputing. 0, 212679, p. 94-104 11 p.

Research output: Contribution to journalConference article

Open Access
3 Scopus citations

Identifying associations between brain imaging phenotypes and genetic factors via a novel structured SCCA approach

Du, L., Zhang, T., Liu, K., Yan, J., Yao, X., Risacher, S. L., Saykin, A., Han, J., Guo, L. & Shen, L., 2017, Information Processing in Medical Imaging - 25th International Conference, IPMI 2017, Proceedings. Springer Verlag, Vol. 10265 LNCS. p. 543-555 13 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10265 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations

Implementation of subjective cognitive decline criteria in research studies

Subjective Cognitive Decline Initiative (SCD-I) Working Group, Mar 1 2017, In : Alzheimer's and Dementia. 13, 3, p. 296-311 16 p.

Research output: Contribution to journalShort survey

107 Scopus citations

Incidence of cognitively defined late-onset Alzheimer's dementia subgroups from a prospective cohort study

Executive Prominent Alzheimer's Disease: Genetics and Risk Factors (EPAD:GRF) Investigators, Dec 2017, In : Alzheimer's and Dementia. 13, 12, p. 1307-1316 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Knowledge-driven binning approach for rare variant association analysis: application to neuroimaging biomarkers in Alzheimer’s disease

Kim, D., Basile, A. O., Bang, L., Horgusluoglu, E., Lee, S., Ritchie, M. D., Saykin, A. J. & Nho, K., May 18 2017, In : BMC medical informatics and decision making. 17, 61.

Research output: Contribution to journalArticle

6 Scopus citations

Longitudinal genotype-phenotype association study via temporal structure auto-learning predictive model

The ADNI, Jan 1 2017, Research in Computational Molecular Biology - 21st Annual International Conference, RECOMB 2017, Proceedings. Sahinalp, S. C. (ed.). Springer Verlag, p. 287-302 16 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10229 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer's disease

Huang, M., Yang, W., Feng, Q., Chen, W., Weiner, M. W., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J. C., Shaw, L. M., Kaye, J., Quinn, J., Silbert, L., Lind, B. & 219 others, Carter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Creech, M. L., Franklin, E., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Love, M. N., Grossman, H., Mitsis, E., Shah, R. C., DeToledo-Morrell, L., Duara, R., Varon, D., Greig, M. T., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J. E., Cerbone, B., Michel, C. A., Pogorelec, D. M., Rusinek, H., De Leon, M. J., Glodzik, L., De Santi, S., Murali Doraiswamy, P., Petrella, J. R., Borges-Neto, S., Wong, T. Z., Coleman, E., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Saleem Ismail, M., Brand, C., Mulnard, R. A., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Swerdlow, R. H., Brooks, W. M., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Kendall, T., Johnson, H., Farlow, M. R., Hake, A. M., Brosch, J. R., Herring, S., Hunt, C., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Hsiung, G. Y. R., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Mesulam, M. M., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Turner, R. S., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Lynn Johnson, P., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Maillard, P., Olichney, J., DeCarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Potkin, S. G., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Adeli, A., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Flashman, L. A., Seltzer, M., Hynes, M. L., Santulli, R. B., Sink, K. M., Gordineer, L., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Raj, B. A. & Fargher, K., Jan 12 2017, In : Scientific reports. 7, 39880.

Research output: Contribution to journalArticle

25 Scopus citations

Mapping longitudinal scientific progress, collaboration and impact of the Alzheimer’s disease neuroimaging initiative

Alzheimer’s Disease Neuroimaging Initiative, Nov 2017, In : PloS one. 12, 11, e0186095.

Research output: Contribution to journalArticle

5 Scopus citations

Metabolic network failures in Alzheimer's disease: A biochemical road map

Alzheimer's Disease Neuroimaging Initiative and the Alzheimer Disease Metabolomics Consortium, Sep 2017, In : Alzheimer's and Dementia. 13, 9, p. 965-984 20 p.

Research output: Contribution to journalArticle

81 Scopus citations

Methylphenidate and memory and attention adaptation training for persistent cognitive symptoms after traumatic brain injury: A randomized, placebo-controlled trial

McDonald, B. C., Flashman, L. A., Arciniegas, D. B., Ferguson, R. J., Xing, L., Harezlak, J., Sprehn, G. C., Hammond, F. M., Maerlender, A. C., Kruck, C. L., Gillock, K. L., Frey, K., Wall, R. N., Saykin, A. J. & McAllister, T. W., Aug 1 2017, In : Neuropsychopharmacology. 42, 9, p. 1766-1775 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Mining outcome-relevant brain imaging genetic associations via three-way sparse canonical correlation analysis in Alzheimer's disease

Hao, X., Li, C., Du, L., Yao, X., Yan, J., Risacher, S. L., Saykin, A., Shen, L. & Zhang, D., Mar 14 2017, In : Scientific Reports. 7, 44272.

Research output: Contribution to journalArticle

7 Scopus citations

Network approaches to systems biology analysis of complex disease: Integrative methods for multi-omics data

Yan, J., Risacher, S. L., Shen, L. & Saykin, A. J., May 30 2017, In : Briefings in Bioinformatics. 19, 6, p. 1370-1381 12 p.

Research output: Contribution to journalArticle

39 Scopus citations

Network-based genome wide study of hippocampal imaging phenotype in Alzheimer's Disease to identify functional interaction modules

Yao, X., Yan, J., Risacher, S., Moore, J., Saykin, A. & Shen, L., Jun 16 2017, 2017 IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc., p. 6170-6174 5 p. 7953342. (ICASSP, IEEE International Conference on Acoustics, Speech and Signal Processing - Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

New probabilistic multi-graph decomposition model to identify consistent human brain network modules

Luo, D., Huo, Z., Wang, Y., Saykin, A. J., Shen, L. & Huang, H., Jan 31 2017, Proceedings - 16th IEEE International Conference on Data Mining, ICDM 2016. Bonchi, F., Wu, X., Baeza-Yates, R., Domingo-Ferrer, J. & Zhou, Z-H. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 301-310 10 p. 7837854. (Proceedings - IEEE International Conference on Data Mining, ICDM).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Novel genetic loci associated with hippocampal volume

Hibar, D. P., Adams, H. H. H., Jahanshad, N., Chauhan, G., Stein, J. L., Hofer, E., Renteria, M. E., Bis, J. C., Arias-Vasquez, A., Ikram, M. K., Desrivières, S., Vernooij, M. W., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S., Armstrong, N. J., Athanasiu, L. & 312 others, Axelsson, T., Beecham, A. H., Beiser, A., Bernard, M., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chen, Q., Ching, C. R. K., Chouraki, V., Cuellar-Partida, G., Crivello, F., Den Braber, A., Doan, N. T., Ehrlich, S., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Grimm, O., Griswold, M. E., Guadalupe, T., Gutman, B. A., Hass, J., Haukvik, U. K., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Jørgensen, K. N., Karbalai, N., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liewald, D. C. M., Lopez, L. M., Luciano, M., MacAre, C., Marquand, A. F., Matarin, M., Mather, K. A., Mattheisen, M., McKay, D. R., Milaneschi, Y., Muñoz Maniega, S., Nho, K., Nugent, A. C., Nyquist, P., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pirpamer, L., Pütz, B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-Santiañez, R., Rommelse, N., Ropele, S., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Saremi, A., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Tordesillas-Gutierrez, D., Toro, R., Trabzuni, D., Trompet, S., Vaidya, D., Van Der Grond, J., Van Der Lee, S. J., Van Der Meer, D., Van Donkelaar, M. M. J., Van Eijk, K. R., Van Erp, T. G. M., Van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Wittfeld, K., Woldehawariat, G., Wolf, C., Wolfers, T., Yanek, L. R., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., Van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Cheng, C. Y., Cichon, S., Cookson, M. R., Corvin, A., Crespo-Facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., De Craen, A. J. M., De Geus, E. J. C., De Jager, P. L., De Zubicaray, G. I., Deary, I. J., Debette, S., Decarli, C., Delanty, N., Depondt, C., Destefano, A., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Enzinger, C., Erk, S., Espeseth, T., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Fornage, M., Foroud, T. M., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Håberg, A. K., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B. C., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J. J., Huentelman, M., Pol, H. E. H., Ikeda, M., Jack, C. R., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J. L., Mattay, V. S., McDonald, C., McIntosh, A. M., McMahon, F. J., McMahon, K. L., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Potkin, S. G., Psaty, B. M., Reppermund, S., Rietschel, M., Roffman, J. L., Romanczuk-Seiferth, N., Rotter, J. I., Ryten, M., Sacco, R. L., Sachdev, P. S., Saykin, A. J., Schmidt, R., Schmidt, H., Schofield, P. R., Sigursson, S., Simmons, A., Singleton, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soininen, H., Steen, V. M., Stott, D. J., Sussmann, J. E., Thalamuthu, A., Toga, A. W., Traynor, B. J., Troncoso, J., Tsolaki, M., Tzourio, C., Uitterlinden, A. G., Hernández, M. C. V., Van Der Brug, M., Van Der Lugt, A., Van Der Wee, N. J. A., Van Haren, N. E. M., Van 'T Ent, D., Van Tol, M. J., Vardarajan, B. N., Vellas, B., Veltman, D. J., Völzke, H., Walter, H., Wardlaw, J. M., Wassink, T. H., Weale, M. E., Weinberger, D. R., Weiner, M. W., Wen, W., Westman, E., White, T., Wong, T. Y., Wright, C. B., Zielke, R. H., Zonderman, A. B., Martin, N. G., Van Duijn, C. M., Wright, M. J., Longstreth, W. T., Schumann, G., Grabe, H. J., Franke, B., Launer, L. J., Medland, S. E., Seshadri, S., Thompson, P. M. & Ikram, M. A., Jan 18 2017, In : Nature communications. 8, 13624.

Research output: Contribution to journalArticle

84 Scopus citations
8 Scopus citations

Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty

Du, L., Liu, K., Yao, X., Yan, J., Risacher, S. L., Han, J., Guo, L., Saykin, A. J., Shen, L., Weiner, M. W., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Morris, J., Shaw, L. M. & 293 others, Khachaturian, Z., Sorensen, G., Carrillo, M., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M. M., Potter, W., Snyder, P., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Balasubramanian, A. B., Mason, J., Sim, I., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., Decarli, C., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Landau, S., Cairns, N. J., Franklin, E., Taylor-Reinwald, L., Lee, V., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T. M., Potkin, S., Faber, K., Kim, S., Nho, K., Thal, L., Buckholtz, N., Albert, M., Frank, R., Hsiao, J., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Pavlik, V., Shibley, V., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Creech, M. L., Franklin, E., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Geldmacher, D., Love, M. N., Griffith, R., Clark, D., Brockington, J., Roberson, E., Grossman, H., Mitsis, E., Shah, R. C., Detoledo-Morrell, L., Duara, R., Greig-Custo, M. T., Barker, W., Onyike, C., D'Agostino, D., Kielb, S., Sadowski, M., Sheikh, M. O., Ulysse, A., Gaikwad, M., Murali Doraiswamy, P., Petrella, J. R., Borges-Neto, S., Wong, T. Z., Coleman, E., Arnold, S. E., Karlawish, J. H., Wolk, D. A., Clark, C. M., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Lopez, O. L., Oakley, M. A., Simpson, D. M., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Ismail, M. S., Brand, C., Preda, A., Nguyen, D., Womack, K., Mathews, D., Quiceno, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Swerdlow, R. H., Brooks, W. M., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Poki-Walker, K., Farlow, M. R., Marie Hake, A., Matthews, B. R., Brosch, J. R., Herring, S., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Mudge, B., Sossi, V., Feldman, H., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Rogers, J., Trost, D., Kertesz, A., Bernick, C., Munic, D., Rogalski, E., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Scott Turner, R., Johnson, K., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Lynn Johnson, P., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Tariot, P., Burke, A., Milliken, A. M., Trncic, N., Fleisher, A., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Kelly, B., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Flashman, L. A., Seltzer, M., Hynes, M. L., Santulli, R. B., Sink, K. M., Gordineer, L., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Tremont, G., Daiello, L. A., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S. K., Ekstam Smith, K., Koleva, H., Nam, K. W., Shim, H., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Ashok Raj, B. & Fargher, K., Dec 1 2017, In : Scientific reports. 7, 1, 14052.

Research output: Contribution to journalArticle

3 Scopus citations

Plasma Tau Association with Brain Atrophy in Mild Cognitive Impairment and Alzheimer's Disease

for the Alzheimer Disease Neuroimaging Initiative, Jan 1 2017, In : Journal of Alzheimer's Disease. 58, 4, p. 1245-1254 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Predicting interrelated Alzheimer’s disease outcomes via new self-learned structured low-rank model

Wang, X., Liu, K., Yan, J., Risacher, S. L., Saykin, A. J., Shen, L. & Huang, H., Jan 1 2017, Information Processing in Medical Imaging - 25th International Conference, IPMI 2017, Proceedings. Zhu, H., Niethammer, M., Styner, M., Zhu, H., Shen, D., Yap, P-T., Aylward, S. & Oguz, I. (eds.). Springer Verlag, p. 198-209 12 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10265 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Sims, R., Van Der Lee, S. J., Naj, A. C., Bellenguez, C., Badarinarayan, N., Jakobsdottir, J., Kunkle, B. W., Boland, A., Raybould, R., Bis, J. C., Martin, E. R., Grenier-Boley, B., Heilmann-Heimbach, S., Chouraki, V., Kuzma, A. B., Sleegers, K., Vronskaya, M., Ruiz, A., Graham, R. R., Olaso, R. & 426 others, Hoffmann, P., Grove, M. L., Vardarajan, B. N., Hiltunen, M., Nöthen, M. M., White, C. C., Hamilton-Nelson, K. L., Epelbaum, J., Maier, W., Choi, S. H., Beecham, G. W., Dulary, C., Herms, S., Smith, A. V., Funk, C. C., Derbois, C., Forstner, A. J., Ahmad, S., Li, H., Bacq, D., Harold, D., Satizabal, C. L., Valladares, O., Squassina, A., Thomas, R., Brody, J. A., Qu, L., Sánchez-Juan, P., Morgan, T., Wolters, F. J., Zhao, Y., Garcia, F. S., Denning, N., Fornage, M., Malamon, J., Naranjo, M. C. D., Majounie, E., Mosley, T. H., Dombroski, B., Wallon, D., Lupton, M. 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A., Powell, J., Golde, T. E., Graff, C., De Jager, P. L., Morgan, K., Ertekin-Taner, N., Combarros, O., Psaty, B. M., Passmore, P., Younkin, S. G., Berr, C., Gudnason, V., Rujescu, D., Dickson, D. W., Dartigues, J. F., Destefano, A. L., Ortega-Cubero, S., Hakonarson, H., Campion, D., Boada, M., Kauwe, J. K., Farrer, L. A., Van Broeckhoven, C., Ikram, M. A., Jones, L., Haines, J. L., Tzourio, C., Launer, L. J., Escott-Price, V., Mayeux, R., Deleuze, J. F., Amin, N., Goate, A. M., Pericak-Vance, M. A., Holmans, P. A., Van Duijn, C. M., Ramirez, A., Wang, L. S., Lambert, J. C., Seshadri, S., Williams, J. & Schellenberg, G. D., Sep 1 2017, In : Nature genetics. 49, 9, p. 1373-1384 12 p.

Research output: Contribution to journalArticle

232 Scopus citations

Recent publications from the Alzheimer's Disease Neuroimaging Initiative: Reviewing progress toward improved AD clinical trials

Alzheimer's Disease Neuroimaging Initiative, Apr 1 2017, In : Alzheimer's and Dementia. 13, 4, p. e1-e85

Research output: Contribution to journalReview article

80 Scopus citations
7 Scopus citations

Sparse Canonical Correlation Analysis via truncated ℓ1-norm with application to brain imaging genetics

Du, L., Zhang, T., Liu, K., Yao, X., Yan, J., Risacher, S. L., Guo, L., Saykin, A. & Shen, L., Jan 17 2017, Proceedings - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016. Institute of Electrical and Electronics Engineers Inc., p. 707-711 5 p. 7822605

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Targeted metabolomics and medication classification data from participants in the ADNI1 cohort

St John-Williams, L., Blach, C., Toledo, J. B., Rotroff, D. M., Kim, S., Klavins, K., Baillie, R., Han, X., Mahmoudiandehkordi, S., Jack, J., Massaro, T. J., Lucas, J. E., Louie, G., Motsinger-Reif, A. A., Risacher, S. L., Saykin, A. J., Kastenmüller, G., Arnold, M., Koal, T., Moseley, M. A. & 5 others, Mangravite, L. M., Peters, M. A., Tenenbaum, J. D., Thompson, J. W. & Kaddurah-Daouk, R., Oct 17 2017, In : Scientific Data. 4, 170140.

Research output: Contribution to journalArticle

18 Scopus citations

Targeted neurogenesis pathway-based gene analysis identifies ADORA2A associated with hippocampal volume in mild cognitive impairment and Alzheimer's disease

Alzheimer's Disease Neuroimaging Initiative (ADNI), Dec 2017, In : Neurobiology of Aging. 60, p. 92-103 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

The Alzheimer's Disease Neuroimaging Initiative 3: Continued innovation for clinical trial improvement

Alzheimer's Disease Neuroimaging Initiative, May 2017, In : Alzheimer's and Dementia. 13, 5, p. 561-571 11 p.

Research output: Contribution to journalReview article

46 Scopus citations

The Impact of Using Different Reference Populations on Measurement of Breast Cancer-Related Cognitive Impairment Rates

Thinking and Living with Cancer (TLC) Study, Nov 24 2017, In : Archives of Clinical Neuropsychology. 33, 8, p. 956-963 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

The Vascular Impairment of Cognition Classification Consensus Study

VICCCS group, Jun 2017, In : Alzheimer's and Dementia. 13, 6, p. 624-633 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

Tissue-specific network-based genome wide study of amygdala imaging phenotypes to identify functional interaction modules

Alzheimer's Disease Neuroimaging Initiative, Oct 15 2017, In : Bioinformatics. 33, 20, p. 3250-3257 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Transcriptome-guided imaging genetic analysis via a novel sparse CCA algorithm

Alzheimer’s Disease Neuroimaging Initiative, 2017, Graphs in Biomedical Image Analysis, Computational Anatomy and Imaging Genetics - 1st International Workshop, GRAIL 2017 6th International Workshop, MFCA 2017 and 3rd International Workshop, MICGen 2017 Held in Conjunction with MICCAI 2017, Proceedings. Springer Verlag, Vol. 10551 LNCS. p. 220-229 10 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10551 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Transethnic genome-wide scan identifies novel Alzheimer's disease loci

Alzheimer's Disease Genetics Consortium, Jul 2017, In : Alzheimer's and Dementia. 13, 7, p. 727-738 12 p.

Research output: Contribution to journalArticle

44 Scopus citations

Two-dimensional enrichment analysis for mining high-level imaging genetic associations

Yao, X., Yan, J., Kim, S., Nho, K., Risacher, S. L., Inlow, M., Moore, J. H., Saykin, A. J. & Shen, L., Mar 1 2017, In : Brain Informatics. 4, 1, p. 27-37 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Unified representation of tractography and diffusion-weighted MRI data using sparse multidimensional arrays

Caiafa, C. F., Sporns, O., Saykin, A. & Pestilli, F., Jan 1 2017, In : Advances in Neural Information Processing Systems. 2017-December, p. 4341-4352 12 p.

Research output: Contribution to journalConference article

4 Scopus citations
2018

Acute White-Matter Abnormalities in Sports-Related Concussion: A Diffusion Tensor Imaging Study from the NCAA-DoD CARE Consortium

Mustafi, S. M., Harezlak, J., Koch, K. M., Nencka, A. S., Meier, T. B., West, J. D., Giza, C. C., DiFiori, J. P., Guskiewicz, K. M., Mihalik, J. P., LaConte, S. M., Duma, S. M., Broglio, S. P., Saykin, A. J., McCrea, M., McAllister, T. W. & Wu, Y. C., Nov 15 2018, In : Journal of neurotrauma. 35, 22, p. 2653-2664 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

A Longitudinal Imaging Genetics Study of Neuroanatomical Asymmetry in Alzheimer's Disease

Alzheimer's Disease Neuroimaging Initiative, Oct 1 2018, In : Biological psychiatry. 84, 7, p. 522-530 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Analysis of shared heritability in common disorders of the brain

The Brainstorm Consortium, Jun 22 2018, In : Science. 360, 6395, 8757.

Research output: Contribution to journalArticle

348 Scopus citations

A Network-Based Framework for Mining High-Level Imaging Genetic Associations

Liang, H., Meng, X., Chen, F., Zhang, Q., Yan, J., Yao, X., Kim, S., Wang, L., Feng, W., Saykin, A. J., Li, J. & Shen, L., Jan 1 2018, Imaging Genetics. Elsevier Inc., p. 119-134 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

A novel SCCA approach via truncated â.," 1-norm and truncated group lasso for brain imaging genetics

Du, L., Liu, K., Zhang, T., Yao, X., Yan, J., Risacher, S. L., Han, J., Guo, L., Saykin, A. J. & Shen, L., Jan 15 2018, In : Bioinformatics. 34, 2, p. 278-285 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Assembly of 809 whole mitochondrial genomes with clinical, imaging, and fluid biomarker phenotyping

The Alzheimer's Disease Neuroimaging Initiative, Apr 2018, In : Alzheimer's and Dementia. 14, 4, p. 514-519 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Assessing brain volume changes in older women with breast cancer receiving adjuvant chemotherapy: A brain magnetic resonance imaging pilot study

Chen, B. T., Sethi, S. K., Jin, T., Patel, S. K., Ye, N., Sun, C. L., Rockne, R. C., Haacke, E. M., Root, J. C., Saykin, A. J., Ahles, T. A., Holodny, A. I., Prakash, N., Mortimer, J., Waisman, J., Yuan, Y., Somlo, G., Li, D., Yang, R., Tan, H. & 3 others, Katheria, V., Morrison, R. & Hurria, A., May 2 2018, In : Breast Cancer Research. 20, 1, 38.

Research output: Contribution to journalArticle

11 Scopus citations

Associations of the top 20 Alzheimer disease risk variants with brain amyloidosis

Apostolova, L. G., Risacher, S. L., Duran, T., Stage, E. C., Goukasian, N., West, J. D., Do, T. M., Grotts, J., Wilhalme, H., Nho, K., Phillips, M., Elashoff, D. & Saykin, A. J., Mar 2018, In : JAMA Neurology. 75, 3, p. 328-341 14 p.

Research output: Contribution to journalArticle

21 Scopus citations

Bootstrapped Sparse Canonical Correlation Analysis: Mining Stable Imaging and Genetic Associations With Implicit Structure Learning. Mining Stable Imaging and Genetic Associations With Implicit Structure Learning.

Yan, J., Du, L., Kim, S., Risacher, S. L., Huang, H., Inlow, M., Moore, J. H., Saykin, A. J. & Shen, L., Jan 1 2018, Imaging Genetics. Elsevier Inc., p. 101-117 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter