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  • Andrew Saykin

Detecting genetic associations with brain imaging phenotypes in Alzheimer's disease via a novel structured SCCA approach

Du, L., Liu, K., Yao, X., Risacher, S. L., Han, J., Saykin, A. J., Guo, L. & Shen, L., Apr 2020, In : Medical Image Analysis. 61, 101656.

Research output: Contribution to journalArticle

Detection of tau in Gerstmann-Sträussler-Scheinker disease (PRNP F198S) by [18F]Flortaucipir PET

Risacher, S. L., Farlow, M. R., Bateman, D. R., Epperson, F., Tallman, E. F., Richardson, R., Murrell, J. R., Unverzagt, F. W., Apostolova, L. G., Bonnin, J. M., Ghetti, B. & Saykin, A. J., Oct 29 2018, In : Acta neuropathologica communications. 6, 1, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Diagnosis-guided method for identifying multi-modality neuroimaging biomarkers associated with genetic risk factors in Alzheimer’s disease

Hao, X., Yan, J., Yao, X., Risacher, S. L., Saykin, A. J., Zhang, D. & Shen, L., Jan 1 2016, In : Pacific Symposium on Biocomputing. p. 108-119 12 p.

Research output: Contribution to journalConference article

3 Scopus citations

Diagnosis status guided brain imaging genetics via integrated regression and sparse canonical correlation analysis

Du, L., Liu, K., Yao, X., Risacher, S. L., Guo, L., Saykin, A. J. & Shen, L., Apr 2019, ISBI 2019 - 2019 IEEE International Symposium on Biomedical Imaging. IEEE Computer Society, p. 356-359 4 p. 8759489. (Proceedings - International Symposium on Biomedical Imaging; vol. 2019-April).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Differential co-expression analysis reveals early stage transcriptomic decoupling in alzheimer's disease

Upadhyaya, Y., Xie, L., Salama, P., Cao, S., Nho, K., Saykin, A. J., Yan, J. & Alzheimer'S Disease Neuroimaging Initiative, F. T., Apr 3 2020, In : BMC Medical Genomics. 13, 53.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Disruption of gene co-expression network along the progression of Alzheimer's disease

Upadhyaya, Y., Xie, L., Salama, P., Nho, K., Saykin, A. J. & Yan, J., May 2019, 2019 IEEE EMBS International Conference on Biomedical and Health Informatics, BHI 2019 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 8834551. (2019 IEEE EMBS International Conference on Biomedical and Health Informatics, BHI 2019 - Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Dysregulated Fc gamma receptor–mediated phagocytosis pathway in Alzheimer's disease: network-based gene expression analysis

AddNeuroMed consortium and the Alzheimer's Disease Neuroimaging Initiative, Apr 2020, In : Neurobiology of Aging. 88, p. 24-32 9 p.

Research output: Contribution to journalArticle

Open Access

Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis

The Alzheimer's Disease Neuroimaging Initiative, Jun 21 2016, In : Nature communications. 7, 11934.

Research output: Contribution to journalArticle

270 Scopus citations

Effects of chemotherapy on aging white matter microstructure: A longitudinal diffusion tensor imaging study

Chen, B. T., Ye, N., Wong, C. W., Patel, S. K., Jin, T., Sun, C. L., Rockne, R. C., Kim, H., Root, J. C., Saykin, A. J., Ahles, T. A., Holodny, A. I., Prakash, N., Mortimer, J., Sedrak, M. S., Waisman, J., Yuan, Y., Li, D., Vazquez, J., Katheria, V. & 1 others, Dale, W., Mar 2020, In : Journal of Geriatric Oncology. 11, 2, p. 290-296 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Effects of traumatic brain injury and posttraumatic stress disorder on development of Alzheimer's disease in Vietnam Veterans using the Alzheimer's Disease Neuroimaging Initiative: Preliminary report

Weiner, M., Harvey, D., Hayes, J., Landau, S., Aisen, P., Petersen, R., Tosun, D., Veitch, D., Jack, C., Decarli, C., Saykin, A., Grafman, J. & Neylan, T., Jun 1 2017, In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 3, 2, p. 177-188 12 p.

Research output: Contribution to journalArticle

23 Scopus citations

Elevated Cerebrospinal Fluid Tau Protein Concentrations on Admission Are Associated with Long-term Neurologic and Cognitive Impairment in Ugandan Children with Cerebral Malaria

Datta, D., Conroy, A. L., Castelluccio, P. F., Ssenkusu, J. M., Park, G. S., Opoka, R. O., Bangirana, P., Idro, R., Saykin, A. J. & John, C. C., Mar 3 2020, In : Clinical Infectious Diseases. 70, 6, p. 1161-1168 8 p.

Research output: Contribution to journalArticle

Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group

Jia, T., Chu, C., Liu, Y., van Dongen, J., Papastergios, E., Armstrong, N. J., Bastin, M. E., Carrillo-Roa, T., den Braber, A., Harris, M., Jansen, R., Liu, J., Luciano, M., Ori, A. P. S., Roiz Santiañez, R., Ruggeri, B., Sarkisyan, D., Shin, J., Sungeun, K., Tordesillas Gutiérrez, D. & 62 others, van’t Ent, D., Ames, D., Artiges, E., Bakalkin, G., Banaschewski, T., Bokde, A. L. W., Brodaty, H., Bromberg, U., Brouwer, R., Büchel, C., Burke Quinlan, E., Cahn, W., de Zubicaray, G. I., Ehrlich, S., Ekström, T. J., Flor, H., Fröhner, J. H., Frouin, V., Garavan, H., Gowland, P., Heinz, A., Hoare, J., Ittermann, B., Jahanshad, N., Jiang, J., Kwok, J. B., Martin, N. G., Martinot, J. L., Mather, K. A., McMahon, K. L., McRae, A. F., Nees, F., Papadopoulos Orfanos, D., Paus, T., Poustka, L., Sämann, P. G., Schofield, P. R., Smolka, M. N., Stein, D. J., Strike, L. T., Teeuw, J., Thalamuthu, A., Trollor, J., Walter, H., Wardlaw, J. M., Wen, W., Whelan, R., Apostolova, L. G., Binder, E. B., Boomsma, D. I., Calhoun, V., Crespo-Facorro, B., Deary, I. J., Hulshoff Pol, H., Ophoff, R. A., Pausova, Z., Sachdev, P. S., Saykin, A., Wright, M. J., Thompson, P. M., Schumann, G. & Desrivières, S., Jan 1 2019, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
19 Scopus citations

Exercise prevents obesity-induced cognitive decline and white matter damage in mice

Graham, L. C., Grabowska, W. A., Chun, Y., Risacher, S. L., Philip, V. M., Saykin, A. J., Sukoff Rizzo, S. J. & Howell, G. R., Aug 2019, In : Neurobiology of Aging. 80, p. 154-172 19 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Exome chip analysis identifies low-frequency and rare variants in MRPL38 for white matter hyperintensities on brain magnetic resonance imaging

neuroCHARGE Working Group, Jan 1 2018, In : Stroke. 49, 8, p. 1812-1819 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies: A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation

Snyder, H. M., Ahles, T., Calderwood, S., Carrillo, M. C., Chen, H., Chang, C. C. H., Craft, S., De Jager, P., Driver, J. A., Fillit, H., Knopman, D., Lotze, M., Tierney, M. C., Petanceska, S., Saykin, A., Seshadri, S., Shineman, D. & Ganguli, M., 2016, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

12 Scopus citations

Externalizing personality traits, empathy, and gray matter volume in healthy young drinkers

Charpentier, J., Dzemidzic, M., West, J., Oberlin, B. G., Eiler, W. J. A., Saykin, A. J. & Kareken, D. A., Feb 28 2016, In : Psychiatry Research - Neuroimaging. 248, p. 64-72 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Fast Multi-Task SCCA Learning with Feature Selection for Multi-Modal Brain Imaging Genetics

Du, L., Liu, K., Yao, X., Risacher, S. L., Han, J., Guo, L., Saykin, A. J. & Shen, L., Jan 21 2019, Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018. Schmidt, H., Griol, D., Wang, H., Baumbach, J., Zheng, H., Callejas, Z., Hu, X., Dickerson, J. & Zhang, L. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 356-361 6 p. 8621298. (Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Functional neuroanatomical correlates of episodic memory impairment in early phase psychosis

Francis, M. M., Hummer, T. A., Vohs, J. L., Yung, M. G., Liffick, E., Mehdiyoun, N. F., Radnovich, A. J., McDonald, B. C., Saykin, A. J. & Breier, A., Mar 1 2016, In : Brain Imaging and Behavior. 10, 1, p. 1-11 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease

International Genomics of Alzheimer's Project (IGAP), ARUK Consortium & GERAD/PERADES, CHARGE, ADGC, EADI, Jan 1 2018, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 10, p. 595-598 4 p.

Research output: Contribution to journalArticle

Genetic architecture of subcortical brain structures in 38,851 individuals

Satizabal, C. L., Adams, H. H. H., Hibar, D. P., White, C. C., Knol, M. J., Stein, J. L., Scholz, M., Sargurupremraj, M., Jahanshad, N., Roshchupkin, G. V., Smith, A. V., Bis, J. C., Jian, X., Luciano, M., Hofer, E., Teumer, A., van der Lee, S. J., Yang, J., Yanek, L. R., Lee, T. V. & 269 others, Li, S., Hu, Y., Koh, J. Y., Eicher, J. D., Desrivières, S., Arias-Vasquez, A., Chauhan, G., Athanasiu, L., Rentería, M. E., Kim, S., Hoehn, D., Armstrong, N. J., Chen, Q., Holmes, A. J., den Braber, A., Kloszewska, I., Andersson, M., Espeseth, T., Grimm, O., Abramovic, L., Alhusaini, S., Milaneschi, Y., Papmeyer, M., Axelsson, T., Ehrlich, S., Roiz-Santiañez, R., Kraemer, B., Håberg, A. K., Jones, H. J., Pike, G. B., Stein, D. J., Stevens, A., Bralten, J., Vernooij, M. W., Harris, T. B., Filippi, I., Witte, A. V., Guadalupe, T., Wittfeld, K., Mosley, T. H., Becker, J. T., Doan, N. T., Hagenaars, S. P., Saba, Y., Cuellar-Partida, G., Amin, N., Hilal, S., Nho, K., Mirza-Schreiber, N., Arfanakis, K., Becker, D. M., Ames, D., Goldman, A. L., Lee, P. H., Boomsma, D. I., Lovestone, S., Giddaluru, S., Le Hellard, S., Mattheisen, M., Bohlken, M. M., Kasperaviciute, D., Schmaal, L., Lawrie, S. M., Agartz, I., Walton, E., Tordesillas-Gutierrez, D., Davies, G. E., Shin, J., Ipser, J. C., Vinke, L. N., Hoogman, M., Jia, T., Burkhardt, R., Klein, M., Crivello, F., Janowitz, D., Carmichael, O., Haukvik, U. K., Aribisala, B. S., Schmidt, H., Strike, L. T., Cheng, C. Y., Risacher, S. L., Pütz, B., Fleischman, D. A., Assareh, A. A., Mattay, V. S., Buckner, R. L., Mecocci, P., Dale, A. M., Cichon, S., Boks, M. P., Matarin, M., Penninx, B. W. J. H., Calhoun, V. D., Chakravarty, M. M., Marquand, A. F., Macare, C., Kharabian Masouleh, S., Oosterlaan, J., Amouyel, P., Hegenscheid, K., Rotter, J. I., Schork, A. J., Liewald, D. C. M., de Zubicaray, G. I., Wong, T. Y., Shen, L., Sämann, P. G., Brodaty, H., Roffman, J. L., de Geus, E. J. C., Tsolaki, M., Erk, S., van Eijk, K. R., Cavalleri, G. L., van der Wee, N. J. A., McIntosh, A. M., Gollub, R. L., Bulayeva, K. B., Bernard, M., Richards, J. S., Himali, J. J., Loeffler, M., Rommelse, N., Hoffmann, W., Westlye, L. T., Valdés Hernández, M. C., Hansell, N. K., van Erp, T. G. M., Wolf, C., Kwok, J. B. J., Vellas, B., Heinz, A., Olde Loohuis, L. M., Delanty, N., Ho, B. C., Ching, C. R. K., Shumskaya, E., Singh, B., Hofman, A., van der Meer, D., Homuth, G., Psaty, B. M., Bastin, M. E., Montgomery, G. W., Foroud, T. M., Reppermund, S., Hottenga, J. J., Simmons, A., Meyer-Lindenberg, A., Cahn, W., Whelan, C. D., van Donkelaar, M. M. J., Yang, Q., Hosten, N., Green, R. C., Thalamuthu, A., Mohnke, S., Hulshoff Pol, H. E., Lin, H., Jack, C. R., Schofield, P. R., Mühleisen, T. W., Maillard, P., Potkin, S. G., Wen, W., Fletcher, E., Toga, A. W., Gruber, O., Huentelman, M., Davey Smith, G., Launer, L. J., Nyberg, L., Jönsson, E. G., Crespo-Facorro, B., Koen, N., Greve, D. N., Uitterlinden, A. G., Weinberger, D. R., Steen, V. M., Fedko, I. O., Groenewold, N. A., Niessen, W. J., Toro, R., Tzourio, C., Longstreth, W. T., Ikram, M. K., Smoller, J. W., van Tol, M. J., Sussmann, J. E., Paus, T., Lemaître, H., Schroeter, M. L., Mazoyer, B., Andreassen, O. A., Holsboer, F., Depondt, C., Veltman, D. J., Turner, J. A., Pausova, Z., Schumann, G., van Rooij, D., Djurovic, S., Deary, I. J., McMahon, K. L., Müller-Myhsok, B., Brouwer, R. M., Soininen, H., Pandolfo, M., Wassink, T. H., Cheung, J. W., Wolfers, T., Martinot, J. L., Zwiers, M. P., Nauck, M., Melle, I., Martin, N. G., Kanai, R., Westman, E., Kahn, R. S., Sisodiya, S. M., White, T., Saremi, A., van Bokhoven, H., Brunner, H. G., Völzke, H., Wright, M. J., van ‘t Ent, D., Nöthen, M. M., Ophoff, R. A., Buitelaar, J. K., Fernández, G., Sachdev, P. S., Rietschel, M., van Haren, N. E. M., Fisher, S. E., Beiser, A. S., Francks, C., Saykin, A. J., Mather, K. A., Romanczuk-Seiferth, N., Hartman, C. A., DeStefano, A. L., Heslenfeld, D. J., Weiner, M. W., Walter, H., Hoekstra, P. J., Nyquist, P. A., Franke, B., Bennett, D. A., Grabe, H. J., Johnson, A. D., Chen, C., van Duijn, C. M., Lopez, O. L., Fornage, M., Wardlaw, J. M., Schmidt, R., DeCarli, C., De Jager, P. L., Villringer, A., Debette, S., Gudnason, V., Medland, S. E., Shulman, J. M., Thompson, P. M., Seshadri, S. & Ikram, M. A., Nov 1 2019, In : Nature genetics. 51, 11, p. 1624-1636 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

Genetic data and cognitively defined late-onset Alzheimer’s disease subgroups

EPAD Study Group, Investigators from ACT, Investigators from ROS, Investigators from MAP, Investigators from ADNI & Investigators from the University of Pittsburgh ADRC, Jan 1 2018, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

5 Scopus citations

Genetic influences on schizophrenia and subcortical brain volumes: Large-scale proof of concept

Psychosis Endophenotypes International Consortium, Feb 23 2016, In : Nature Neuroscience. 19, 3, p. 420-431 12 p.

Research output: Contribution to journalArticle

111 Scopus citations

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), Mar 1 2019, In : Nature genetics. 51, 3, p. 414-430 17 p.

Research output: Contribution to journalArticle

139 Scopus citations

Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways

Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dec 1 2019, In : Scientific reports. 9, 1, 14498.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Genome-wide association and interaction studies of CSF T-tau/Aβ42 ratio in ADNI cohort

Li, J., Zhang, Q., Chen, F., Meng, X., Liu, W., Chen, D., Yan, J., Kim, S., Wang, L., Feng, W., Saykin, A. J., Liang, H. & Shen, L., Sep 2017, In : Neurobiology of Aging. 57, p. 247.e1-247.e8

Research output: Contribution to journalArticle

10 Scopus citations

Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers

Alzheimer’s Disease Neuroimaging Initiative (ADNI) & The Alzheimer Disease Genetic Consortium (ADGC), May 1 2017, In : Acta Neuropathologica. 133, 5, p. 839-856 18 p.

Research output: Contribution to journalArticle

38 Scopus citations

Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging

for the Alzheimer’s Disease Neuroimaging Initiative (ADNI), Jan 1 2018, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

4 Scopus citations

Genome-wide association study of language performance in Alzheimer's disease

The Alzheimer's Disease Neuroimaging Initiative, Sep 2017, In : Brain and Language. 172, p. 22-29 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Genome-wide association study of prolactin levels in blood plasma and cerebrospinal fluid

for the Alzheimer's Disease Neuroimaging Initiative, Jun 29 2016, In : BMC genomics. 17, 436.

Research output: Contribution to journalArticle

2 Scopus citations

Genome-wide network-assisted association and enrichment study of amyloid imaging phenotype in alzheimer’s disease

Alzheimer’s Disease Neuroimaging Initiative, Jan 1 2019, In : Current Alzheimer research. 16, 13, p. 1163-1174 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Genome-wide network-based pathway analysis of CSF t-tau/Aβ1-42 ratio in the ADNI cohort

for the Alzheimer's Disease Neuroimaging Initiative, May 30 2017, In : BMC genomics. 18, 1, 421.

Research output: Contribution to journalArticle

5 Scopus citations

Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging

Nelson, P. T., Katsumata, Y., Nho, K., Artiushin, S. C., Jicha, G. A., Wang, W. X., Abner, E. L., Saykin, A. J., Kukull, W. A., Alzheimer’s Disease Neuroimaging Initiative (ADNI), D. N. I. ADNI. & Fardo, D. W., Dec 1 2016, In : Acta Neuropathologica. 132, 6, p. 841-858 18 p.

Research output: Contribution to journalArticle

12 Scopus citations

GPU Accelerated Browser for Neuroimaging Genomics

Alzheimer’s Disease Neuroimaging Initiative, Oct 1 2018, In : Neuroinformatics. 16, 3-4, p. 393-402 10 p.

Research output: Contribution to journalArticle

Gray matter density reduction associated with adjuvant chemotherapy in older women with breast cancer

Chen, B. T., Jin, T., Patel, S. K., Ye, N., Sun, C. L., Ma, H., Rockne, R. C., Root, J. C., Saykin, A. J., Ahles, T. A., Holodny, A. I., Prakash, N., Mortimer, J., Waisman, J., Yuan, Y., Li, D., Somlo, G., Vazquez, J., Levi, A., Tan, H. & 3 others, Yang, R., Katheria, V. & Hurria, A., Nov 1 2018, In : Breast Cancer Research and Treatment. 172, 2, p. 363-370 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Heritability estimation of reliable connectomic features

Xie, L., Amico, E., Salama, P., Wu, Y. C., Fang, S., Sporns, O., Saykin, A. J., Goñi, J., Yan, J. & Shen, L., Jan 1 2018, Connectomics in NeuroImaging - 2nd International Workshop, CNI 2018, Held in Conjunction with MICCAI 2018, Proceedings. Wu, G., Schirmer, M. D., Chung, A. W., Rekik, I. & Munsell, B. (eds.). Springer Verlag, p. 58-66 9 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11083 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations
13 Scopus citations

Identification of associations between genotypes and longitudinal phenotypes via temporally-constrained group sparse canonical correlation analysis

Hao, X., Li, C., Yan, J., Yao, X., Risacher, S. L., Saykin, A. J., Shen, L. & Zhang, D., Jul 15 2017, In : Bioinformatics. 33, 14, p. i341-i349

Research output: Contribution to journalArticle

7 Scopus citations

Identification of discriminative imaging proteomics associations in Alzheimer’s disease via a novel sparse correlation model

Alzheimer's Disease Neuroimaging Initiative, Jan 1 2017, In : Pacific Symposium on Biocomputing. 0, 212679, p. 94-104 11 p.

Research output: Contribution to journalConference article

Open Access
3 Scopus citations

Identification of exon skipping events associated with Alzheimer's disease in the human hippocampus

Han, S., Miller, J. E., Byun, S., Kim, D., Risacher, S. L., Saykin, A. J., Lee, Y. & Nho, K., Jan 31 2019, In : BMC Medical Genomics. 12, 13.

Research output: Contribution to journalArticle

4 Scopus citations

Identifying associations between brain imaging phenotypes and genetic factors via a novel structured SCCA approach

Du, L., Zhang, T., Liu, K., Yan, J., Yao, X., Risacher, S. L., Saykin, A., Han, J., Guo, L. & Shen, L., 2017, Information Processing in Medical Imaging - 25th International Conference, IPMI 2017, Proceedings. Springer Verlag, Vol. 10265 LNCS. p. 543-555 13 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10265 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations

Identifying Candidate Genetic Associations with MRI-Derived AD-Related ROI via Tree-Guided Sparse Learning

Hao, X., Yao, X., Risacher, S. L., Saykin, A. J., Yu, J., Wang, H., Tan, L., Shen, L. & Zhang, D., Nov 1 2019, In : IEEE/ACM Transactions on Computational Biology and Bioinformatics. 16, 6, p. 1986-1996 11 p., 8355682.

Research output: Contribution to journalArticle

Identifying Multimodal Intermediate Phenotypes Between Genetic Risk Factors and Disease Status in Alzheimer’s Disease

Hao, X., Yao, X., Yan, J., Risacher, S. L., Saykin, A. J., Zhang, D., Shen, L. & for the Alzheimer’s Disease Neuroimaging Initiative, T. A. D. N. I., Oct 1 2016, In : Neuroinformatics. 14, 4, p. 439-452 14 p.

Research output: Contribution to journalArticle

11 Scopus citations

Identifying progressive imaging genetic patterns via multi-task sparse canonical correlation analysis: A longitudinal study of the ADNI cohort

Du, L., Liu, K., Zhu, L., Yao, X., Risacher, S. L., Guo, L., Saykin, A. J. & Shen, L., Jul 15 2019, In : Bioinformatics. 35, 14, p. i474-i483 btz320.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Identifying significant gene-environment interactions using a combination of screening testing and hierarchical false discovery rate control

The Alzheimer's Disease Neuroimaging Initiative, Nov 1 2016, In : Genetic epidemiology. 40, 7, p. 544-557 14 p.

Research output: Contribution to journalArticle

7 Scopus citations
1 Scopus citations

Implementation of subjective cognitive decline criteria in research studies

Subjective Cognitive Decline Initiative (SCD-I) Working Group, Mar 1 2017, In : Alzheimer's and Dementia. 13, 3, p. 296-311 16 p.

Research output: Contribution to journalShort survey

103 Scopus citations

Incidence of cognitively defined late-onset Alzheimer's dementia subgroups from a prospective cohort study

Executive Prominent Alzheimer's Disease: Genetics and Risk Factors (EPAD:GRF) Investigators, Dec 2017, In : Alzheimer's and Dementia. 13, 12, p. 1307-1316 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Integration of bioinformatics and imaging informatics for identifying rare PSEN1 variants in Alzheimer's disease

Nho, K., Horgusluoglu, E., Kim, S., Risacher, S. L., Kim, D., Foroud, T., Aisen, P. S., Petersen, R. C., Jack, C. R., Shaw, L. M., Trojanowski, J. Q., Weiner, M. W., Green, R. C., Toga, A. W. & Saykin, A. J., Aug 12 2016, In : BMC Medical Genomics. 9, 30.

Research output: Contribution to journalArticle

9 Scopus citations

Interactive Machine Learning by Visualization: A Small Data Solution

Li, H., Fang, S., Mukhopadhyay, S., Saykin, A. J. & Shen, L., Jan 22 2019, Proceedings - 2018 IEEE International Conference on Big Data, Big Data 2018. Song, Y., Liu, B., Lee, K., Abe, N., Pu, C., Qiao, M., Ahmed, N., Kossmann, D., Saltz, J., Tang, J., He, J., Liu, H. & Hu, X. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 3513-3521 9 p. 8621952. (Proceedings - 2018 IEEE International Conference on Big Data, Big Data 2018).

Research output: Chapter in Book/Report/Conference proceedingConference contribution