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  • Andrew Saykin

Acute White-Matter Abnormalities in Sports-Related Concussion: A Diffusion Tensor Imaging Study from the NCAA-DoD CARE Consortium

Mustafi, S. M., Harezlak, J., Koch, K. M., Nencka, A. S., Meier, T. B., West, J. D., Giza, C. C., DiFiori, J. P., Guskiewicz, K. M., Mihalik, J. P., LaConte, S. M., Duma, S. M., Broglio, S. P., Saykin, A. J., McCrea, M., McAllister, T. W. & Wu, Y. C., Nov 15 2018, In : Journal of neurotrauma. 35, 22, p. 2653-2664 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

Adult neurogenesis and neurodegenerative diseases: A systems biology perspective

Horgusluoglu, E., Nudelman, K., Nho, K. & Saykin, A. J., Jan 1 2017, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 174, 1, p. 93-112 20 p.

Research output: Contribution to journalReview article

53 Scopus citations

A fast SCCA algorithm for big data analysis in brain imaging genetics

Alzheimer’s Disease Neuroimaging Initiative, 2017, Graphs in Biomedical Image Analysis, Computational Anatomy and Imaging Genetics - 1st International Workshop, GRAIL 2017 6th International Workshop, MFCA 2017 and 3rd International Workshop, MICGen 2017 Held in Conjunction with MICCAI 2017, Proceedings. Springer Verlag, Vol. 10551 LNCS. p. 210-219 10 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10551 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Age at injury is associated with the long-term cognitive outcome of traumatic brain injuries

Alzheimer's Disease Neuroimaging Initiative, Jan 1 2017, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 6, p. 196-200 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

A Longitudinal Imaging Genetics Study of Neuroanatomical Asymmetry in Alzheimer's Disease

Alzheimer's Disease Neuroimaging Initiative, Oct 1 2018, In : Biological psychiatry. 84, 7, p. 522-530 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Alpha-synuclein (SNCA) polymorphisms exert protective effects on memory after mild traumatic brain injury

Shee, K., Lucas, A., Flashman, L. A., Nho, K., Tsongalis, G. J., McDonald, B. C., Saykin, A. J., McAllister, T. W. & Rhodes, C. H., Sep 6 2016, In : Neuroscience Letters. 630, p. 241-246 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Altered brain connectivity in early postmenopausal women with subjective cognitive impairment

Vega, J. N., Zurkovsky, L., Albert, K., Melo, A., Boyd, B., Dumas, J., Woodward, N., McDonald, B., Saykin, A., Park, J. H., Naylor, M. & Newhouse, P. A., Sep 23 2016, In : Frontiers in Neuroscience. 10, SEP, 433.

Research output: Contribution to journalArticle

15 Scopus citations

Alzheimer disease brain atrophy subtypes are associated with cognition and rate of decline

Alzheimer's Disease Neuroimaging Initiative, Jan 1 2017, In : Neurology. 89, 21, p. 2176-2186 11 p.

Research output: Contribution to journalArticle

25 Scopus citations

Alzheimer's disease risk polymorphisms regulate gene expression in the ZCWPW1 and the CELF1 loci

Alzheimer's Disease Genetics Consortium (ADGC), Feb 2016, In : PloS one. 11, 2, e0148717.

Research output: Contribution to journalArticle

33 Scopus citations

Analysis of shared heritability in common disorders of the brain

The Brainstorm Consortium, Jun 22 2018, In : Science. 360, 6395, 8757.

Research output: Contribution to journalArticle

348 Scopus citations

A Network-Based Framework for Mining High-Level Imaging Genetic Associations

Liang, H., Meng, X., Chen, F., Zhang, Q., Yan, J., Yao, X., Kim, S., Wang, L., Feng, W., Saykin, A. J., Li, J. & Shen, L., Jan 1 2018, Imaging Genetics. Elsevier Inc., p. 119-134 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

A new statistical image analysis approach and its application to Hippocampal morphometry

ADNI, Jan 1 2016, Medical Imaging and Augmented Reality - 7th International Conference, MIAR 2016, Proceedings. Liao, H., Zheng, G., Lee, S-L., Cattin, P. & Jannin, P. (eds.). Springer Verlag, p. 302-310 9 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 9805 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

A novel Alzheimer disease locus located near the gene encoding tau protein

Jun, G., Ibrahim-Verbaas, C. A., Vronskaya, M., Lambert, J. C., Chung, J., Naj, A. C., Kunkle, B. W., Wang, L. S., Bis, J. C., Bellenguez, C., Harold, D., Lunetta, K. L., Destefano, A. L., Grenier-Boley, B., Sims, R., Beecham, G. W., Smith, A. V., Chouraki, V., Hamilton-Nelson, K. L., Ikram, M. A. & 332 others, Fievet, N., Denning, N., Martin, E. R., Schmidt, H., Kamatani, Y., Dunstan, M. L., Valladares, O., Laza, A. R., Zelenika, D., Ramirez, A., Foroud, T. M., Choi, S. H., Boland, A., Becker, T., Kukull, W. A., Van Der Lee, S. J., Pasquier, F., Cruchaga, C., Beekly, D., Fitzpatrick, A. L., Hanon, O., Gill, M., Barber, R., Gudnason, V., Campion, D., Love, S., Bennett, D. A., Amin, N., Berr, C., Tsolaki, M., Buxbaum, J. D., Lopez, O. L., Deramecourt, V., Fox, N. C., Cantwell, L. B., Tárraga, L., Dufouil, C., Hardy, J., Crane, P. K., Eiriksdottir, G., Hannequin, D., Clarke, R., Evans, D., Mosley, T. H., Letenneur, L., Brayne, C., Maier, W., De Jager, P., Emilsson, V., Dartigues, J. F., Hampel, H., Kamboh, M. I., De Bruijn, R. F. A. G., Tzourio, C., Pastor, P., Larson, E. B., Rotter, J. I., O'Donovan, M. C., Montine, T. J., Nalls, M. A., Mead, S., Reiman, E. M., Jonsson, P. V., Holmes, C., St George-Hyslop, P. H., Boada, M., Passmore, P., Wendland, J. R., Schmidt, R., Morgan, K., Winslow, A. R., Powell, J. F., Carasquillo, M., Younkin, S. G., Jakobsdóttir, J., Kauwe, J. S. K., Wilhelmsen, K. C., Rujescu, D., Nöthen, M. M., Hofman, A., Jones, L., Haines, J. L., Psaty, B. M., Van Broeckhoven, C., Holmans, P., Launer, L. J., Mayeux, R., Lathrop, M., Goate, A. M., Escott-Price, V., Seshadri, S., Pericak-Vance, M. A., Amouyel, P., Williams, J., Van Duijn, C. M., Schellenberg, G. D., Farrer, L. A., Adams, P. M., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barmada, M. M., Barnes, L. L., Beach, T. G., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cribbs, D. H., Crocco, E. A., DeCarli, C., DeKosky, S. T., Yesim Demirci, F., Dick, M., Dickson, D. W., Doody, R. S., Duara, R., Ertekin-Taner, N., Faber, K. M., Fairchild, T. J., Fallon, K. B., Farlow, M. R., Ferris, S., Frosch, M. P., Galasko, D. R., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Glass, J. D., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Harrell, L. E., Head, E., Honig, L. S., Huebinger, R. M., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Karydas, A., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lin, C. F., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Morris, J. C., Mukherjee, S., Murrell, J. R., Myers, A. J., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Partch, A., Paulson, H. L., Perry, W., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reisch, J. S., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Royall, D. R., Sager, M. A., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Wishnek, S., Woltjer, R. L., Wright, C. B., Wu, C. K., Yu, C. E., Yu, L., Thomas, C., Gerrish, A., Chapman, J., Stretton, A., Morgan, A., Oldham, H., Owen, M. J., Kehoe, P. G., Medway, C., Brown, K., Lord, J., Turton, J., Hooper, N. M., Vardy, E., Warren, J. D., Schott, J. M., Uphill, J., Hollingworth, P., Ryan, N., Rossor, M., Collinge, J., Ben-Shlomo, Y., Makrina, D., Gkatzima, O., Lupton, M., Koutroumani, M., Avramidou, D., Germanou, A., Jessen, F., Riedel-Heller, S., Dichgans, M., Heun, R., Kölsch, H., Schürmann, B., Herold, C., Lacour, A., Drichel, D., Hoffmann, P., Kornhuber, J., Gu, W., Feulner, T., Mayhaus, M., Pichler, S., Riemenschneider, M., van den Bussche, H., Lawlor, B., Lynch, A., Mann, D., Smith, A. D., Warden, D., Wilcock, G., Heuser, I., Wiltfang, J., Frölich, L., Hüll, M., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Singleton, A. B., Guerreiro, R., Russo, G., Jöckel, K. H., Moebus, S., Klopp, N., Wichmann, H. E., Ma, L., Bisceglio, G., Fisher, E., Warner, N., Pickering-Brown, S., Craig, D., Johnston, J. A., McGuinness, B., Todd, S., Rubinsztein, D. C., Lovestone, S., Bayer, A., Gallacher, J., Proitsi, P. & Ortega-Cubero, S., Jan 1 2016, In : Molecular Psychiatry. 21, 1, p. 108-117 10 p.

Research output: Contribution to journalArticle

87 Scopus citations

A novel SCCA approach via truncated â.," 1-norm and truncated group lasso for brain imaging genetics

Du, L., Liu, K., Zhang, T., Yao, X., Yan, J., Risacher, S. L., Han, J., Guo, L., Saykin, A. J. & Shen, L., Jan 15 2018, In : Bioinformatics. 34, 2, p. 278-285 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Apathy is associated with ventral striatum volume in schizophrenia spectrum disorder

Roth, R. M., Garlinghouse, M. A., Flashman, L. A., Koven, N. S., Cara Pendergrass, J., Ford, J. C., McAllister, T. W. & Saykin, A., 2016, In : Journal of Neuropsychiatry and Clinical Neurosciences. 28, 3, p. 191-194 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Assembly of 809 whole mitochondrial genomes with clinical, imaging, and fluid biomarker phenotyping

The Alzheimer's Disease Neuroimaging Initiative, Apr 2018, In : Alzheimer's and Dementia. 14, 4, p. 514-519 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Assessing brain volume changes in older women with breast cancer receiving adjuvant chemotherapy: A brain magnetic resonance imaging pilot study

Chen, B. T., Sethi, S. K., Jin, T., Patel, S. K., Ye, N., Sun, C. L., Rockne, R. C., Haacke, E. M., Root, J. C., Saykin, A. J., Ahles, T. A., Holodny, A. I., Prakash, N., Mortimer, J., Waisman, J., Yuan, Y., Somlo, G., Li, D., Yang, R., Tan, H. & 3 others, Katheria, V., Morrison, R. & Hurria, A., May 2 2018, In : Breast Cancer Research. 20, 1, 38.

Research output: Contribution to journalArticle

11 Scopus citations

Assessment of the genetic variance of late-onset Alzheimer's disease

Alzheimer's Disease Genetics Consortium (ADGC), May 1 2016, In : Neurobiology of Aging. 41, p. 200.e13-200.e20

Research output: Contribution to journalArticle

Open Access
24 Scopus citations

Association analysis of rare variants near the APOE region with CSF and neuroimaging biomarkers of Alzheimer’s disease

Nho, K., Kim, S., Horgusluoglu, E., Risacher, S. L., Shen, L., Kim, D., Lee, S., Foroud, T., Shaw, L. M., Trojanowski, J. Q., Aisen, P. S., Petersen, R. C., Jack, C. R., Weiner, M. W., Green, R. C., Toga, A. W. & Saykin, A. J., May 24 2017, In : BMC Medical Genomics. 10, 29.

Research output: Contribution to journalArticle

9 Scopus citations

Association between anticholinergic medication use and cognition, brain metabolism, and brain atrophy in cognitively normal older adults

Alzheimer's Disease Neuroimaging Initiative, Jun 2016, In : JAMA Neurology. 73, 6, p. 721-732 12 p.

Research output: Contribution to journalArticle

103 Scopus citations

Association of Blood Biomarkers With Acute Sport-Related Concussion in Collegiate Athletes: Findings From the NCAA and Department of Defense CARE Consortium

And the CARE Consortium Investigators, Jan 3 2020, In : JAMA Network Open. 3, 1, p. e1919771

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Association of plasma neurofilament light with neurodegeneration in patients with Alzheimer disease

Alzheimer's Disease Neuroimaging Initiative, May 2017, In : JAMA Neurology. 74, 5, p. 557-566 10 p.

Research output: Contribution to journalArticle

180 Scopus citations

Associations of the top 20 Alzheimer disease risk variants with brain amyloidosis

Apostolova, L. G., Risacher, S. L., Duran, T., Stage, E. C., Goukasian, N., West, J. D., Do, T. M., Grotts, J., Wilhalme, H., Nho, K., Phillips, M., Elashoff, D. & Saykin, A. J., Mar 2018, In : JAMA Neurology. 75, 3, p. 328-341 14 p.

Research output: Contribution to journalArticle

21 Scopus citations

BECA: A Software Tool for Integrated Visualization of Human Brain Data

Li, H., Fang, S., Zigon, B., Sporns, O., Saykin, A. J., Goñi, J. & Shen, L., Jan 1 2017, Brain Informatics - International Conference, BI 2017, Proceedings. Zeng, Y., Xu, B., Martone, M., He, Y., Peng, H., Luo, Q. & Kotaleski, J. H. (eds.). Springer Verlag, p. 285-291 7 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10654 LNAI).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Bootstrapped Sparse Canonical Correlation Analysis: Mining Stable Imaging and Genetic Associations With Implicit Structure Learning. Mining Stable Imaging and Genetic Associations With Implicit Structure Learning.

Yan, J., Du, L., Kim, S., Risacher, S. L., Huang, H., Inlow, M., Moore, J. H., Saykin, A. J. & Shen, L., Jan 1 2018, Imaging Genetics. Elsevier Inc., p. 101-117 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study

Varma, V. R., Oommen, A. M., Varma, S., Casanova, R., An, Y., Andrews, R. M., O’Brien, R., Pletnikova, O., Troncoso, J. C., Toledo, J., Baillie, R., Arnold, M., Kastenmueller, G., Nho, K., Doraiswamy, P. M., Saykin, A. J., Kaddurah-Daouk, R., Legido-Quigley, C. & Thambisetty, M., Jan 2018, In : PLoS Medicine. 15, 1, e1002482.

Research output: Contribution to journalArticle

60 Scopus citations

Brain explorer for connectomic analysis

for the Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2017, In : Brain Informatics. 4, 4, p. 253-269 17 p.

Research output: Contribution to journalArticle

1 Scopus citations

Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states

Mahjoub, I., Mahjoub, M. A., Rekik, I., Weiner, M., Aisen, P., Petersen, R., Jack, C., Jagust, W., Trojanowki, J., Toga, A., Beckett, L., Green, R., Saykin, A., Morris, J., Shaw, L., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R. & 221 others, Dolen, S., Schneider, L., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J., Lord, J., Mason, S., Albers, C., Knopman, D., Johnson, K., Doody, R., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L., Bell, K., Ances, B., Carroll, M., Creech, M., Franklin, E., Mintun, M., Schneider, S., Oliver, A., Marson, D., Grifth, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Natelson Love, M., Grossman, H., Mitsis, E., Shah, R., Detoledo-Morrell, L., Duara, R., Varon, D., Greig, M., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J., Cerbone, B., Michel, C., Pogorelec, D., Rusinek, H., De Leon, M., Glodzik, L., De Santi, S., Doraiswamy, P., Petrella, J., Borges-Neto, S., Wong, T., Coleman, E., Smith, C., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Porsteinsson, A., Goldstein, B., Martin, K., Makino, K., Ismail, M., Brand, C., Mulnard, R., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A., Lah, J., Cellar, J., Burns, J., Swerdlow, R., Brooks, W., Apostolova, L., Tingus, K., Woo, E., Silverman, D., Lu, P., Bartzokis, G., Graf-Radford, N., Parftt, F., Kendall, T., Johnson, H., Farlow, M., Hake, A. M., Matthews, B., Brosch, J., Herring, S., Hunt, C., Dyck, C., Carson, R., MacAvoy, M., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Mesulam, M. M., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Turner, R. S., Johnson, K., Reynolds, B., Sperling, R., Johnson, K., Marshall, G., Yesavage, J., Taylor, J., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M., Belden, C., Jacobson, S., Sirrel, S., Kowall, N., Killiany, R., Budson, A., Norbash, A., Johnson, P. L., Obisesan, T., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C., Potkin, S., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D., Kataki, M., Adeli, A., Zimmerman, E., Celmins, D., Brown, A., Pearlson, G., Blank, K., Anderson, K., Flashman, L., Seltzer, M., Hynes, M., Santulli, R., Sink, K., Gordineer, L., Williamson, J., Garg, P., Watkins, F., Ott, B., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H., Miller, B., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Raj, B. A. & Fargher, K., Dec 1 2018, In : Scientific reports. 8, 1, 4103.

Research output: Contribution to journalArticle

24 Scopus citations

Brain-wide structural connectivity alterations under the control of Alzheimer risk genes

Yan, J., Vinesh Raja, V., Huang, Z., Amico, E., Nho, K., Fang, S., Sporns, O., Wu, Y. C., Saykin, A., Goñi, J. & Shen, L., Jan 1 2020, In : International Journal of Computational Biology and Drug Design. 13, 1, p. 58-70 13 p.

Research output: Contribution to journalArticle

Building a surface atlas of hippocampal subfields from high resolution T2-weighted MRI scans using landmark-free surface registration

Cong, S., Rizkalla, M., Salama, P., Risacher, S. L., West, J. D., Wu, Y. C., Apostolova, L., Tallman, E., Saykin, A. J. & Shen, L., Jul 2 2016, 2016 IEEE 59th International Midwest Symposium on Circuits and Systems, MWSCAS 2016. Institute of Electrical and Electronics Engineers Inc., 7870109. (Midwest Symposium on Circuits and Systems; vol. 0).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Cancer-related cognitive outcomes among older breast cancer survivors in the thinking and living with cancer study

Mandelblatt, J. S., Small, B. J., Luta, G., Hurria, A., Jim, H., McDonald, B. C., Graham, D., Zhou, X., Clapp, J., Zhai, W., Breen, E., Carroll, J. E., Denduluri, N., Dilawari, A., Extermann, M., Isaacs, C., Jacobsen, P. B., Kobayashi, L. C., Holohan Nudelman, K., Root, J. & 6 others, Stern, R. A., Tometich, D., Turner, R., VanMeter, J. W., Saykin, A. J. & Ahles, T., Nov 10 2018, In : Journal of Clinical Oncology. 36, 32, p. 3211-3222 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer's Disease via Fusion of Clinical, Imaging and Omic Features

Singanamalli, A., Wang, H., Madabhushi, A., Weiner, M., Aisen, P., Petersen, R., Jack, C., Jagust, W., Trojanowki, J., Toga, A., Beckett, L., Green, R., Saykin, A., Morris, J., Shaw, L., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R. & 221 others, Dolen, S., Schneider, L., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J., Lord, J., Mason, S., Albers, C., Knopman, D., Johnson, K., Doody, R., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L., Bell, K., Ances, B., Carroll, M., Creech, M., Franklin, E., Mintun, M., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Natelson Love, M., Grossman, H., Mitsis, E., Shah, R., Detoledo-Morrell, L., Duara, R., Varon, D., Greig, M., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J., Cerbone, B., Michel, C., Pogorelec, D., Rusinek, H., De Leon, M., Glodzik, L., De Santi, S., Doraiswamy, P., Petrella, J., Borges-Neto, S., Wong, T., Coleman, E., Smith, C., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Porsteinsson, A., Goldstein, B., Martin, K., Makino, K., Ismail, M., Brand, C., Mulnard, R., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A., Lah, J., Cellar, J., Burns, J., Swerdlow, R., Brooks, W., Apostolova, L., Tingus, K., Woo, E., Silverman, D., Lu, P., Bartzokis, G., Graff-Radford, N., Parfitt, F., Kendall, T., Johnson, H., Farlow, M., Marie Hake, A., Matthews, B., Brosch, J., Herring, S., Hunt, C., Dyck, C., Carson, R., MacAvoy, M., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Mesulam, M. M., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Scott Turner, R., Johnson, K., Reynolds, B., Sperling, R., Johnson, K., Marshall, G., Yesavage, J., Taylor, J., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M., Belden, C., Jacobson, S., Sirrel, S., Kowall, N., Killiany, R., Budson, A., Norbash, A., Lynn Johnson, P., Obisesan, T., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Robbartha, Johnson, S., Asthana, S., Carlsson, C., Potkin, S., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D., Kataki, M., Adeli, A., Zimmerman, E., Celmins, D., Brown, A., Pearlson, G., Blank, K., Anderson, K., Flashman, L., Seltzer, M., Hynes, M., Santulli, R., Sink, K., Gordineer, L., Williamson, J., Garg, P., Watkins, F., Ott, B., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H., Miller, B., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Ashok Raj, B. & Fargher, K., Dec 1 2017, In : Scientific reports. 7, 1, 8137.

Research output: Contribution to journalArticle

3 Scopus citations

Cerebral perfusion and gray matter changes associated with chemotherapy-induced peripheral neuropathy

Nudelman, K. N. H., McDonald, B. C., Wang, Y., Smith, D. J., West, J. D., O'Neill, D. P., Zanville, N. R., Champion, V. L., Schneider, B. P. & Saykin, A. J., Mar 1 2016, In : Journal of Clinical Oncology. 34, 7, p. 677-683 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer’s Pathophysiology

The Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2020, In : Scientific reports. 10, 1, 2975.

Research output: Contribution to journalArticle

Open Access

Characteristic patterns of inter- and intra-hemispheric metabolic connectivity in patients with stable and progressive mild cognitive impairment and Alzheimer’s disease

for the Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2018, In : Scientific reports. 8, 1, 13807.

Research output: Contribution to journalArticle

4 Scopus citations

Characterizing gene and protein crosstalks in subjects at risk of developing Alzheimer's disease: A new computational approach

for the Alzheimer's Disease Neuroimaging Initiative, Sep 1 2017, In : Processes. 5, 3, 47.

Research output: Contribution to journalArticle

1 Scopus citations

Codon bias among synonymous rare variants is associated with alzheimer’s disease imaging biomarker

Alzheimer’s Disease Neuroimaging Initiative (ADNI), Jan 1 2018, In : Pacific Symposium on Biocomputing. 0, 212669, p. 365-376 12 p.

Research output: Contribution to journalConference article

4 Scopus citations

Cognitive complaints in older adults at risk for Alzheimer's disease are associated with altered resting-state networks

Contreras, J. A., Goñi, J., Risacher, S. L., Amico, E., Yoder, K., Dzemidzic, M., West, J. D., McDonald, B. C., Farlow, M. R., Sporns, O. & Saykin, A. J., Jan 1 2017, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 6, p. 40-49 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Cognitive function prior to systemic therapy and subsequent well-being in older breast cancer survivors: Longitudinal findings from the Thinking and Living with Cancer Study

Kobayashi, L. C., Cohen, H. J., Zhai, W., Zhou, X., Small, B. J., Luta, G., Hurria, A., Carroll, J., Tometich, D., McDonald, B. C., Graham, D., Jim, H. S. L., Jacobsen, P., Root, J. C., Saykin, A. J., Ahles, T. A. & Mandelblatt, J., Jun 1 2020, In : Psycho-Oncology. 29, 6, p. 1051-1059 9 p.

Research output: Contribution to journalArticle

Detecting genetic associations with brain imaging phenotypes in Alzheimer's disease via a novel structured SCCA approach

Du, L., Liu, K., Yao, X., Risacher, S. L., Han, J., Saykin, A. J., Guo, L. & Shen, L., Apr 2020, In : Medical Image Analysis. 61, 101656.

Research output: Contribution to journalArticle

Detection of tau in Gerstmann-Sträussler-Scheinker disease (PRNP F198S) by [18F]Flortaucipir PET

Risacher, S. L., Farlow, M. R., Bateman, D. R., Epperson, F., Tallman, E. F., Richardson, R., Murrell, J. R., Unverzagt, F. W., Apostolova, L. G., Bonnin, J. M., Ghetti, B. & Saykin, A. J., Oct 29 2018, In : Acta neuropathologica communications. 6, 1, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Diagnosis-guided method for identifying multi-modality neuroimaging biomarkers associated with genetic risk factors in Alzheimer’s disease

Hao, X., Yan, J., Yao, X., Risacher, S. L., Saykin, A. J., Zhang, D. & Shen, L., Jan 1 2016, In : Pacific Symposium on Biocomputing. p. 108-119 12 p.

Research output: Contribution to journalConference article

3 Scopus citations

Differential co-expression analysis reveals early stage transcriptomic decoupling in alzheimer's disease

Upadhyaya, Y., Xie, L., Salama, P., Cao, S., Nho, K., Saykin, A. J., Yan, J. & Alzheimer'S Disease Neuroimaging Initiative, F. T., Apr 3 2020, In : BMC Medical Genomics. 13, 53.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Dysregulated Fc gamma receptor–mediated phagocytosis pathway in Alzheimer's disease: network-based gene expression analysis

AddNeuroMed consortium and the Alzheimer's Disease Neuroimaging Initiative, Apr 2020, In : Neurobiology of Aging. 88, p. 24-32 9 p.

Research output: Contribution to journalArticle

Open Access

Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis

The Alzheimer's Disease Neuroimaging Initiative, Jun 21 2016, In : Nature communications. 7, 11934.

Research output: Contribution to journalArticle

275 Scopus citations

Effects of chemotherapy on aging white matter microstructure: A longitudinal diffusion tensor imaging study

Chen, B. T., Ye, N., Wong, C. W., Patel, S. K., Jin, T., Sun, C. L., Rockne, R. C., Kim, H., Root, J. C., Saykin, A. J., Ahles, T. A., Holodny, A. I., Prakash, N., Mortimer, J., Sedrak, M. S., Waisman, J., Yuan, Y., Li, D., Vazquez, J., Katheria, V. & 1 others, Dale, W., Mar 2020, In : Journal of Geriatric Oncology. 11, 2, p. 290-296 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Effects of traumatic brain injury and posttraumatic stress disorder on development of Alzheimer's disease in Vietnam Veterans using the Alzheimer's Disease Neuroimaging Initiative: Preliminary report

Weiner, M., Harvey, D., Hayes, J., Landau, S., Aisen, P., Petersen, R., Tosun, D., Veitch, D., Jack, C., Decarli, C., Saykin, A., Grafman, J. & Neylan, T., Jun 1 2017, In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 3, 2, p. 177-188 12 p.

Research output: Contribution to journalArticle

23 Scopus citations

Elevated Cerebrospinal Fluid Tau Protein Concentrations on Admission Are Associated with Long-term Neurologic and Cognitive Impairment in Ugandan Children with Cerebral Malaria

Datta, D., Conroy, A. L., Castelluccio, P. F., Ssenkusu, J. M., Park, G. S., Opoka, R. O., Bangirana, P., Idro, R., Saykin, A. J. & John, C. C., Mar 3 2020, In : Clinical Infectious Diseases. 70, 6, p. 1161-1168 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

The Alzheimer’s Disease Genetics Consortium, Dec 1 2020, In : Nature communications. 11, 1, 667.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations