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  • Andrew Saykin

Association between anticholinergic medication use and cognition, brain metabolism, and brain atrophy in cognitively normal older adults

Alzheimer's Disease Neuroimaging Initiative, Jun 2016, In : JAMA Neurology. 73, 6, p. 721-732 12 p.

Research output: Contribution to journalArticle

103 Scopus citations

Association analysis of rare variants near the APOE region with CSF and neuroimaging biomarkers of Alzheimer’s disease

Nho, K., Kim, S., Horgusluoglu, E., Risacher, S. L., Shen, L., Kim, D., Lee, S., Foroud, T., Shaw, L. M., Trojanowski, J. Q., Aisen, P. S., Petersen, R. C., Jack, C. R., Weiner, M. W., Green, R. C., Toga, A. W. & Saykin, A. J., May 24 2017, In : BMC Medical Genomics. 10, 29.

Research output: Contribution to journalArticle

9 Scopus citations

Assessment of the genetic variance of late-onset Alzheimer's disease

Alzheimer's Disease Genetics Consortium (ADGC), May 1 2016, In : Neurobiology of Aging. 41, p. 200.e13-200.e20

Research output: Contribution to journalArticle

Open Access
25 Scopus citations

Assessing brain volume changes in older women with breast cancer receiving adjuvant chemotherapy: A brain magnetic resonance imaging pilot study

Chen, B. T., Sethi, S. K., Jin, T., Patel, S. K., Ye, N., Sun, C. L., Rockne, R. C., Haacke, E. M., Root, J. C., Saykin, A. J., Ahles, T. A., Holodny, A. I., Prakash, N., Mortimer, J., Waisman, J., Yuan, Y., Somlo, G., Li, D., Yang, R., Tan, H. & 3 others, Katheria, V., Morrison, R. & Hurria, A., May 2 2018, In : Breast Cancer Research. 20, 1, 38.

Research output: Contribution to journalArticle

11 Scopus citations

Assembly of 809 whole mitochondrial genomes with clinical, imaging, and fluid biomarker phenotyping

The Alzheimer's Disease Neuroimaging Initiative, Apr 2018, In : Alzheimer's and Dementia. 14, 4, p. 514-519 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Apathy is associated with ventral striatum volume in schizophrenia spectrum disorder

Roth, R. M., Garlinghouse, M. A., Flashman, L. A., Koven, N. S., Cara Pendergrass, J., Ford, J. C., McAllister, T. W. & Saykin, A., 2016, In : Journal of Neuropsychiatry and Clinical Neurosciences. 28, 3, p. 191-194 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

A novel SCCA approach via truncated â.," 1-norm and truncated group lasso for brain imaging genetics

Du, L., Liu, K., Zhang, T., Yao, X., Yan, J., Risacher, S. L., Han, J., Guo, L., Saykin, A. J. & Shen, L., Jan 15 2018, In : Bioinformatics. 34, 2, p. 278-285 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

A Novel Joint Brain Network Analysis Using Longitudinal Alzheimer’s Disease Data

The Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific reports. 9, 1, 19589.

Research output: Contribution to journalArticle

Open Access

A novel Alzheimer disease locus located near the gene encoding tau protein

Jun, G., Ibrahim-Verbaas, C. A., Vronskaya, M., Lambert, J. C., Chung, J., Naj, A. C., Kunkle, B. W., Wang, L. S., Bis, J. C., Bellenguez, C., Harold, D., Lunetta, K. L., Destefano, A. L., Grenier-Boley, B., Sims, R., Beecham, G. W., Smith, A. V., Chouraki, V., Hamilton-Nelson, K. L., Ikram, M. A. & 332 others, Fievet, N., Denning, N., Martin, E. R., Schmidt, H., Kamatani, Y., Dunstan, M. L., Valladares, O., Laza, A. R., Zelenika, D., Ramirez, A., Foroud, T., Choi, S. H., Boland, A., Becker, T., Kukull, W. A., Van Der Lee, S. J., Pasquier, F., Cruchaga, C., Beekly, D., Fitzpatrick, A. L., Hanon, O., Gill, M., Barber, R., Gudnason, V., Campion, D., Love, S., Bennett, D. A., Amin, N., Berr, C., Tsolaki, M., Buxbaum, J. D., Lopez, O. L., Deramecourt, V., Fox, N. C., Cantwell, L. B., Tárraga, L., Dufouil, C., Hardy, J., Crane, P. K., Eiriksdottir, G., Hannequin, D., Clarke, R., Evans, D., Mosley, T. H., Letenneur, L., Brayne, C., Maier, W., De Jager, P., Emilsson, V., Dartigues, J. F., Hampel, H., Kamboh, M. I., De Bruijn, R. F. A. G., Tzourio, C., Pastor, P., Larson, E. B., Rotter, J. I., O'Donovan, M. C., Montine, T. J., Nalls, M. A., Mead, S., Reiman, E. M., Jonsson, P. V., Holmes, C., St George-Hyslop, P. H., Boada, M., Passmore, P., Wendland, J. R., Schmidt, R., Morgan, K., Winslow, A. R., Powell, J. F., Carasquillo, M., Younkin, S. G., Jakobsdóttir, J., Kauwe, J. S. K., Wilhelmsen, K. C., Rujescu, D., Nöthen, M. M., Hofman, A., Jones, L., Haines, J. L., Psaty, B. M., Van Broeckhoven, C., Holmans, P., Launer, L. J., Mayeux, R., Lathrop, M., Goate, A. M., Escott-Price, V., Seshadri, S., Pericak-Vance, M. A., Amouyel, P., Williams, J., Van Duijn, C. M., Schellenberg, G. D., Farrer, L. A., Adams, P. M., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barmada, M. M., Barnes, L. L., Beach, T. G., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cribbs, D. H., Crocco, E. A., DeCarli, C., DeKosky, S. T., Yesim Demirci, F., Dick, M., Dickson, D. W., Doody, R. S., Duara, R., Ertekin-Taner, N., Faber, K. M., Fairchild, T. J., Fallon, K. B., Farlow, M. R., Ferris, S., Frosch, M. P., Galasko, D. R., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Glass, J. D., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Harrell, L. E., Head, E., Honig, L. S., Huebinger, R. M., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Karydas, A., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lin, C. F., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Morris, J. C., Mukherjee, S., Murrell, J. R., Myers, A. J., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Partch, A., Paulson, H. L., Perry, W., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reisch, J. S., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Royall, D. R., Sager, M. A., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Wishnek, S., Woltjer, R. L., Wright, C. B., Wu, C. K., Yu, C. E., Yu, L., Thomas, C., Gerrish, A., Chapman, J., Stretton, A., Morgan, A., Oldham, H., Owen, M. J., Kehoe, P. G., Medway, C., Brown, K., Lord, J., Turton, J., Hooper, N. M., Vardy, E., Warren, J. D., Schott, J. M., Uphill, J., Hollingworth, P., Ryan, N., Rossor, M., Collinge, J., Ben-Shlomo, Y., Makrina, D., Gkatzima, O., Lupton, M., Koutroumani, M., Avramidou, D., Germanou, A., Jessen, F., Riedel-Heller, S., Dichgans, M., Heun, R., Kölsch, H., Schürmann, B., Herold, C., Lacour, A., Drichel, D., Hoffmann, P., Kornhuber, J., Gu, W., Feulner, T., Mayhaus, M., Pichler, S., Riemenschneider, M., van den Bussche, H., Lawlor, B., Lynch, A., Mann, D., Smith, A. D., Warden, D., Wilcock, G., Heuser, I., Wiltfang, J., Frölich, L., Hüll, M., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Singleton, A. B., Guerreiro, R., Russo, G., Jöckel, K. H., Moebus, S., Klopp, N., Wichmann, H. E., Ma, L., Bisceglio, G., Fisher, E., Warner, N., Pickering-Brown, S., Craig, D., Johnston, J. A., McGuinness, B., Todd, S., Rubinsztein, D. C., Lovestone, S., Bayer, A., Gallacher, J., Proitsi, P. & Ortega-Cubero, S., Jan 1 2016, In : Molecular Psychiatry. 21, 1, p. 108-117 10 p.

Research output: Contribution to journalArticle

87 Scopus citations

A new statistical image analysis approach and its application to Hippocampal morphometry

ADNI, Jan 1 2016, Medical Imaging and Augmented Reality - 7th International Conference, MIAR 2016, Proceedings. Liao, H., Zheng, G., Lee, S-L., Cattin, P. & Jannin, P. (eds.). Springer Verlag, p. 302-310 9 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 9805 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

A Network-Based Framework for Mining High-Level Imaging Genetic Associations

Liang, H., Meng, X., Chen, F., Zhang, Q., Yan, J., Yao, X., Kim, S., Wang, L., Feng, W., Saykin, A. J., Li, J. & Shen, L., Jan 1 2018, Imaging Genetics. Elsevier Inc., p. 119-134 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Analysis of shared heritability in common disorders of the brain

The Brainstorm Consortium, Jun 22 2018, In : Science. 360, 6395, 8757.

Research output: Contribution to journalArticle

348 Scopus citations

Alzheimer's disease risk polymorphisms regulate gene expression in the ZCWPW1 and the CELF1 loci

Alzheimer's Disease Genetics Consortium (ADGC), Feb 2016, In : PloS one. 11, 2, e0148717.

Research output: Contribution to journalArticle

33 Scopus citations

Alzheimer disease brain atrophy subtypes are associated with cognition and rate of decline

Alzheimer's Disease Neuroimaging Initiative, Jan 1 2017, In : Neurology. 89, 21, p. 2176-2186 11 p.

Research output: Contribution to journalArticle

25 Scopus citations

Altered brain connectivity in early postmenopausal women with subjective cognitive impairment

Vega, J. N., Zurkovsky, L., Albert, K., Melo, A., Boyd, B., Dumas, J., Woodward, N., McDonald, B. C., Saykin, A. J., Park, J. H., Naylor, M. & Newhouse, P. A., Sep 23 2016, In : Frontiers in Neuroscience. 10, SEP, 433.

Research output: Contribution to journalArticle

15 Scopus citations

Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers

Alzheimer's Disease Neuroimaging Initiative and the Alzheimer Disease Metabolomics Consortium, Feb 2019, In : Alzheimer's and Dementia. 15, 2, p. 232-244 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—An emerging role for gut microbiome

Alzheimer's Disease Neuroimaging Initiative and the Alzheimer Disease Metabolomics Consortium, Jan 2019, In : Alzheimer's and Dementia. 15, 1, p. 76-92 17 p.

Research output: Contribution to journalArticle

Open Access
38 Scopus citations

Alpha-synuclein (SNCA) polymorphisms exert protective effects on memory after mild traumatic brain injury

Shee, K., Lucas, A., Flashman, L. A., Nho, K., Tsongalis, G. J., McDonald, B. C., Saykin, A. J., McAllister, T. W. & Rhodes, C. H., Sep 6 2016, In : Neuroscience Letters. 630, p. 241-246 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

A Longitudinal Imaging Genetics Study of Neuroanatomical Asymmetry in Alzheimer's Disease

Alzheimer's Disease Neuroimaging Initiative, Oct 1 2018, In : Biological psychiatry. 84, 7, p. 522-530 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Age at injury is associated with the long-term cognitive outcome of traumatic brain injuries

Alzheimer's Disease Neuroimaging Initiative, 2017, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 6, p. 196-200 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

A fast SCCA algorithm for big data analysis in brain imaging genetics

Alzheimer’s Disease Neuroimaging Initiative, 2017, Graphs in Biomedical Image Analysis, Computational Anatomy and Imaging Genetics - 1st International Workshop, GRAIL 2017 6th International Workshop, MFCA 2017 and 3rd International Workshop, MICGen 2017 Held in Conjunction with MICCAI 2017, Proceedings. Springer Verlag, Vol. 10551 LNCS. p. 210-219 10 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10551 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Adult neurogenesis and neurodegenerative diseases: A systems biology perspective

Horgusluoglu, E., Nudelman, K., Nho, K. & Saykin, A. J., Jan 1 2017, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 174, 1, p. 93-112 20 p.

Research output: Contribution to journalReview article

53 Scopus citations

A dirty multi-task learning method for multi-modal brain imaging genetics

for the Alzheimer’s Disease Neuroimaging Initiative, Jan 1 2019, Medical Image Computing and Computer Assisted Intervention – MICCAI 2019 - 22nd International Conference, Proceedings. Shen, D., Yap, P-T., Liu, T., Peters, T. M., Khan, A., Staib, L. H., Essert, C. & Zhou, S. (eds.). Springer, p. 447-455 9 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11767 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Acute White-Matter Abnormalities in Sports-Related Concussion: A Diffusion Tensor Imaging Study from the NCAA-DoD CARE Consortium

Mustafi, S. M., Harezlak, J., Koch, K. M., Nencka, A. S., Meier, T. B., West, J. D., Giza, C. C., DiFiori, J. P., Guskiewicz, K. M., Mihalik, J. P., LaConte, S. M., Duma, S. M., Broglio, S. P., Saykin, A. J., McCrea, M., McAllister, T. W. & Wu, Y. C., Nov 15 2018, In : Journal of neurotrauma. 35, 22, p. 2653-2664 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

A blood-based signature of cerebrospinal fluid Aβ 1–42 status

Alzheimer’s Disease Metabolomics Consortium & Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific reports. 9, 1, 4163.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations