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  • Nadia Carlesso
Article

Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion

Kumar, B., Garcia, M., Weng, L., Jung, X., Murakami, J. L., Hu, X., McDonald, T., Lin, A., Kumar, A. R., Digiusto, D. L., Stein, A. S., Pullarkat, V. A., Hui, S. K., Carlesso, N., Kuo, Y. H., Bhatia, R., Marcucci, G. & Chen, C. C., Mar 1 2018, In : Leukemia. 32, 3, p. 575-587 13 p.

Research output: Contribution to journalArticle

66 Scopus citations

Bidirectional notch signaling and osteocyte-derived factors in the bone marrow microenvironment promote tumor cell proliferation and bone destruction in multiple myeloma

Delgado-Calle, J., Anderson, J., Cregor, M. D., Hiasa, M., Chirgwin, J. M., Carlesso, N., Yoneda, T., Mohammad, K. S., Plotkin, L. I., Roodman, G. D. & Bellido, T., Mar 1 2016, In : Cancer Research. 76, 5, p. 1089-1100 12 p.

Research output: Contribution to journalArticle

75 Scopus citations

Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia

Zhang, B., Nguyen, L. X. T., Li, L., Zhao, D., Kumar, B., Wu, H., Lin, A., Pellicano, F., Hopcroft, L., Su, Y. L., Copland, M., Holyoake, T. L., Kuo, C. J., Bhatia, R., Snyder, D. S., Ali, H., Stein, A. S., Brewer, C., Wang, H., McDonald, T. & 12 others, Swiderski, P., Troadec, E., Chen, C. C., Dorrance, A., Pullarkat, V., Yuan, Y. C., Perrotti, D., Carlesso, N., Forman, S. J., Kortylewski, M., Kuo, Y. H. & Marcucci, G., May 1 2018, In : Nature Medicine. 24, 4, p. 450-462 13 p.

Research output: Contribution to journalArticle

19 Scopus citations
1 Scopus citations

Copper 64-labeled daratumumab as a PET/CT imaging tracer for multiple myeloma

Caserta, E., Chea, J., Minnix, M., Viola, D., Vonderfecht, S., Yazaki, P., Crow, D., Khalife, J., Sanchez, J. F., Palmer, J. M., Hui, S., Carlesso, N., Keats, J., Kim, Y., Buettner, R., Marcucci, G., Rosen, S., Shively, J., Colcher, D., Krishnan, A. & 1 others, Pichiorri, F., Feb 15 2018, In : Blood. 131, 7, p. 741-745 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

Neuropeptide Y regulates a vascular gateway for hematopoietic stem and progenitor cells

Singh, P., Hoggatt, J., Kamocka, M., Mohammad, K., Saunders, M. R., Li, H., Speth, J., Carlesso, N., Guise, T. & Pelus, L., Dec 1 2017, In : Journal of Clinical Investigation. 127, 12, p. 4527-4540 14 p.

Research output: Contribution to journalArticle

18 Scopus citations

Protein Tyrosine Phosphatase PRL2 Mediates Notch and Kit Signals in Early T Cell Progenitors

Kobayashi, M., Nabinger, S. C., Bai, Y., Yoshimoto, M., Gao, R., Chen, S., Yao, C., Dong, Y., Zhang, L., Rodriguez, S., Yashiro-Ohtani, Y., Pear, W. S., Carlesso, N., Yoder, M. C., Kapur, R., Kaplan, M. H., Daniel Lacorazza, H., Zhang, Z. Y. & Liu, Y., Apr 1 2017, In : STEM CELLS. 35, 4, p. 1053-1064 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

S6K1 regulates hematopoietic stem cell self-renewal and leukemia maintenance

Ghosh, J., Kobayashi, M., Ramdas, B., Chatterjee, A., Ma, P., Mali, R. S., Carlesso, N., Liu, Y., Plas, D. R., Chan, R. & Kapur, R., Jul 1 2016, In : Journal of Clinical Investigation. 126, 7, p. 2621-2625 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

Sepsis induces hematopoietic stem cell exhaustion and myelosuppression through distinct contributions of TRIF and MYD88

Zhang, H., Rodriguez, S., Wang, L., Wang, S., Serezani, H., Kapur, R., Cardoso, A. A. & Carlesso, N., Jun 14 2016, In : Stem Cell Reports. 6, 6, p. 940-956 17 p.

Research output: Contribution to journalArticle

28 Scopus citations

SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function

Sun, J., He, X., Zhu, Y., Ding, Z., Dong, H., Feng, Y., Du, J., Wang, H., Wu, X., Zhang, L., Yu, X., Lin, A., McDonald, T., Zhao, D., Wu, H., Hua, W. K., Zhang, B., Feng, L., Tohyama, K., Bhatia, R. & 13 others, Oberdoerffer, P., Chung, Y. J., Aplan, P. D., Boultwood, J., Pellagatti, A., Khaled, S., Kortylewski, M., Pichiorri, F., Kuo, Y. H., Carlesso, N., Marcucci, G., Jin, H. & Li, L., Sep 6 2018, In : Cell Stem Cell. 23, 3, p. 355-369.e9

Research output: Contribution to journalArticle

14 Scopus citations

Structural and functional characterization of endothelial microparticles released by cigarette smoke

Serban, K. A., Rezania, S., Petrusca, D. N., Poirier, C., Cao, D., Justice, M. J., Patel, M., Tsvetkova, I., Kamocki, K., Mikosz, A., Schweitzer, K. S., Jacobson, S., Cardoso, A., Carlesso, N., Hubbard, W. C., Kechris, K., Dragnea, B., Berdyshev, E. V., McClintock, J. & Petrache, I., Aug 17 2016, In : Scientific reports. 6, 31596.

Research output: Contribution to journalArticle

39 Scopus citations

Targeting cell membrane HDM2: A novel therapeutic approach for acute myeloid leukemia

Wang, H., Zhao, D., Nguyen, L. X., Wu, H., Li, L., Dong, D., Troadec, E., Zhu, Y., Hoang, D. H., Stein, A. S., Al Malki, M., Aldoss, I., Lin, A., Ghoda, L. Y., McDonald, T., Pichiorri, F., Carlesso, N., Kuo, Y. H., Zhang, B., Jin, J. & 1 others, Marcucci, G., Jan 1 2020, In : Leukemia. 34, 1, p. 75-86 12 p.

Research output: Contribution to journalArticle

Therapeutic targeting of the E3 ubiquitin ligase SKP2 in T-ALL

Rodriguez, S., Abundis, C., Boccalatte, F., Mehrotra, P., Chiang, M. Y., Yui, M. A., Wang, L., Zhang, H., Zollman, A., Bonfim-Silva, R., Kloetgen, A., Palmer, J., Sandusky, G., Wunderlich, M., Kaplan, M. H., Mulloy, J. C., Marcucci, G., Aifantis, I., Cardoso, A. A. & Carlesso, N., May 1 2020, In : Leukemia. 34, 5, p. 1241-1252 12 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
Comment/debate

Erratum: Copper 64–labeled daratumumab as a PET/CT imaging tracer for multiple myeloma (Blood (2018) 131:7 (741-745) DOI: 10.1182/blood-2017-09-807263)

Caserta, E., Chea, J., Minnix, M., Poku, E. K., Viola, D., Vonderfecht, S., Yazaki, P., Crow, D., Khalife, J., Sanchez, J. F., Palmer, J. M., Hui, S., Carlesso, N., Keats, J., Kim, Y., Buettner, R., Marcucci, G., Rosen, S., Shively, J., Colcher, D. & 2 others, Krishnan, A. & Pichiorri, F., Jun 21 2018, In : Blood. 131, 25, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations