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  • Chandy John
2017

Effect of transmission intensity on hotspots and micro-epidemiology of malaria in sub-Saharan Africa

on behalf of The Hotspot Group Authors, Jun 30 2017, In : BMC medicine. 15, 1, 121.

Research output: Contribution to journalArticle

14 Scopus citations

Elevated cerebrospinal fluid tumour necrosis factor is associated with acute and long-term neurocognitive impairment in cerebral malaria

Shabani, E., Ouma, B. J., Idro, R., Bangirana, P., Opoka, R. O., Park, G. S., Conroy, A. L. & John, C. C., Jul 2017, In : Parasite Immunology. 39, 7, e12438.

Research output: Contribution to journalArticle

13 Scopus citations

High postdischarge morbidity in Ugandan children with severe malarial anemia or cerebral malaria

Opoka, R. O., Hamre, K. E. S., Brand, N., Bangirana, P., Idro, R. & John, C., Sep 1 2017, In : Journal of the Pediatric Infectious Diseases Society. 6, 3, p. e41-e48

Research output: Contribution to journalArticle

4 Scopus citations

Interferon- γ responses to Plasmodium falciparum vaccine candidate antigens decrease in the absence of malaria transmission

Ayieko, C., Ogola, B. S., Ochola, L., Ngwena, G. A. M., Ayodo, G., Hodges, J. S., Noland, G. S. & John, C. C., 2017, In : PeerJ. 2017, 1, e2855.

Research output: Contribution to journalArticle

2 Scopus citations

Neurodevelopment: The impact of nutrition and inflammation during early to middle childhood in low-resource settings

John, C. C., Black, M. M. & Nelson, C. A., Apr 2017, In : Pediatrics. 139, p. S59-S71

Research output: Contribution to journalReview article

25 Scopus citations

Novel use Of Hydroxyurea in an African Region with Malaria (NOHARM): a trial for children with sickle cell anemia

Opoka, R. O., Ndugwa, C. M., Latham, T. S., Lane, A., Hume, H. A., Kasirye, P., Hodges, J. S., Ware, R. E. & John, C. C., Dec 14 2017, In : Blood. 130, 24, p. 2585-2593 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

Plasmodium falciparum EPCR-binding PfEMP1 expression increases with malaria disease severity and is elevated in retinopathy negative cerebral malaria

Shabani, E., Hanisch, B., Opoka, R. O., Lavstsen, T. & John, C. C., Oct 13 2017, In : BMC medicine. 15, 1, 183.

Research output: Contribution to journalArticle

16 Scopus citations

Selecting measures for the neurodevelopmental assessment of children in low- and middle-income countries

Semrud-Clikeman, M., Romero, R. A. A., Prado, E. L., Shapiro, E. G., Bangirana, P. & John, C. C., Oct 3 2017, In : Child Neuropsychology. 23, 7, p. 761-802 42 p.

Research output: Contribution to journalReview article

25 Scopus citations

Sero-catalytic and Antibody Acquisition Models to Estimate Differing Malaria Transmission Intensities in Western Kenya

Weber, G. E., White, M. T., Babakhanyan, A., Sumba, P. O., Vulule, J., Ely, D., John, C., Angov, E., Lanar, D., Dutta, S., Narum, D. L., Horii, T., Cowman, A., Beeson, J., Smith, J., Kazura, J. W. & Dent, A. E., Dec 1 2017, In : Scientific reports. 7, 1, 16821.

Research output: Contribution to journalArticle

1 Scopus citations

Supporting global health at the pediatric department level: Why and how

Pitt, M. B., Moore, M. A., John, C. C., Batra, M., Butteris, S. M., Airewele, G. E., Suchdev, P. S. & Steinhoff, M. C., Jun 2017, In : Pediatrics. 139, 6, e20163939.

Research output: Contribution to journalArticle

11 Scopus citations

The Benjamin H. Kean travel fellowship in tropical medicine: Assessment of impact at 15 years

Carman, A. S. & John, C. C., 2017, In : American Journal of Tropical Medicine and Hygiene. 97, 3, p. 958-963 6 p.

Research output: Contribution to journalArticle

2016

Acute kidney injury is common in pediatric severe malaria and is associated with increased mortality

Conroy, A. L., Hawkes, M., Elphinstone, R. E., Morgan, C., Hermann, L., Barker, K. R., Namasopo, S., Opoka, R. O., John, C. C., Liles, W. C. & Kain, K. C., Apr 1 2016, In : Open Forum Infectious Diseases. 3, 2

Research output: Contribution to journalArticle

31 Scopus citations

Alterations in Systemic Extracellular Heme and Hemopexin Are Associated with Adverse Clinical Outcomes in Ugandan Children with Severe Malaria

Elphinstone, R. E., Conroy, A. L., Hawkes, M., Hermann, L., Namasopo, S., Warren, H. S., John, C. C., Liles, W. C. & Kain, K. C., Oct 15 2016, In : Journal of Infectious Diseases. 214, 8, p. 1268-1275 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Cerebral malaria is associated with long-term mental health disorders: A cross sectional survey of a long-term cohort

Idro, R., Kakooza-Mwesige, A., Asea, B., Ssebyala, K., Bangirana, P., Opoka, R. O., Lubowa, S. K., Semrud-Clikeman, M., John, C. C. & Nalugya, J., Mar 31 2016, In : Malaria Journal. 15, 1, 184.

Research output: Contribution to journalArticle

27 Scopus citations

Comparison of iron status 28 d after provision of antimalarial treatment with iron therapy compared with antimalarial treatment alone in Ugandan children with severe malaria

Cusick, S. E., Opoka, R. O., Ssemata, A. S., Georgieff, M. K. & John, C. C., Mar 1 2016, In : American Journal of Clinical Nutrition. 103, 3, p. 919-925 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Delaying Iron therapy until 28 days after antimalarial treatment is associated with greater Iron incorporation and equivalent hematologic recovery after 56 days in children: A randomized controlled trial

Cusick, S. E., Opoka, R. O., Abrams, S. A., John, C. C., Georgieff, M. K. & Mupere, E., Jan 1 2016, In : Journal of Nutrition. 146, 9, p. 1769-1774 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Differing causes of lactic acidosis and deep breathing in cerebral malaria and severe malarial anemia may explain differences in acidosis-related mortality

Brand, N. R., Opoka, R. O., Hamre, K. E. S. & John, C. C., Sep 1 2016, In : PloS one. 11, 9, e0163728.

Research output: Contribution to journalArticle

7 Scopus citations

Exploring experimental cerebral malaria pathogenesis through the characterisation of host-derived plasma microparticle protein content

Tiberti, N., Latham, S. L., Bush, S., Cohen, A., Opoka, R. O., John, C. C., Juillard, A., Grau, G. E. & Combes, V., Dec 5 2016, In : Scientific reports. 6, 37871.

Research output: Contribution to journalArticle

15 Scopus citations

Host biomarkers are associated with response to therapy and long-term mortality in pediatric severe malaria

Conroy, A. L., Hawkes, M., McDonald, C. R., Kim, H., Higgins, S. J., Barker, K. R., Namasopo, S., Opoka, R. O., John, C. C., Liles, W. C. & Kain, K. C., 2016, In : Open Forum Infectious Diseases. 3, 3

Research output: Contribution to journalArticle

10 Scopus citations

Iron, inflammation, and malaria in the pregnant woman and her child: Saving lives, saving brains

Cusick, S. E. & John, C., Oct 1 2016, In : American Journal of Tropical Medicine and Hygiene. 95, 4, p. 739-740 2 p.

Research output: Contribution to journalEditorial

3 Scopus citations

Longevity of genotype-specific immune responses to Plasmodium falciparum merozoite surface protein 1 in Kenyan children from regions of different malaria transmission intensity

Bowman, N. M., Juliano, J. J., Snider, C. J., Kharabora, O., Meshnick, S. R., Vulule, J., John, C. C. & Moormann, A. M., Sep 2016, In : American Journal of Tropical Medicine and Hygiene. 95, 3, p. 580-587 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Long-term behavioral problems in children with severe malaria

Ssenkusu, J. M., Hodges, J. S., Opoka, R. O., Idro, R., Shapiro, E., John, C. C. & Bangirana, P., Nov 2016, In : Pediatrics. 138, 5, e20161965.

Research output: Contribution to journalArticle

16 Scopus citations

Methemoglobin and nitric oxide therapy in Ugandan children hospitalized for febrile illness: Results from a prospective cohort study and randomized double-blind placebo-controlled trial

Conroy, A. L., Hawkes, M., Hayford, K., Hermann, L., McDonald, C. R., Sharma, S., Namasopo, S., Opoka, R. O., John, C. C., Liles, W. C., Miller, C. & Kain, K. C., Nov 4 2016, In : BMC Pediatrics. 16, 1, 177.

Research output: Contribution to journalArticle

4 Scopus citations

Neurocognitive domains affected by cerebral malaria and severe malarial anemia in children

Bangirana, P., Opoka, R. O., Boivin, M. J., Idro, R., Hodges, J. S. & John, C. C., Feb 1 2016, In : Learning and Individual Differences. 46, p. 38-44 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Perspective piece successful global health research partnerships: What makes them work?

John, C. C., Ayodo, G. & Musoke, P., Jan 2016, In : American Journal of Tropical Medicine and Hygiene. 94, 1, p. 5-7 3 p.

Research output: Contribution to journalReview article

16 Scopus citations

Primaquine plus artemisinin combination therapy for reduction of malaria transmission: Promise and risk

John, C., 2016, In : BMC Medicine. 14, 1, 65.

Research output: Contribution to journalComment/debate

9 Scopus citations

Splenomegaly of unknown etiology in Congolese refugees applying for resettlement to the United States — Uganda, 2015

Goers, M., Ope, M. O., Samuels, A., Gitu, N., Akandwanaho, S., Nabwami, G., Nyoka, R., Cetron, M. S., Dalal, W., Conroy, A. L., Cantey, P., John, C., Naoum, M., Weinberg, M., Marano, N. & Stauffer, W., Sep 9 2016, In : Morbidity and Mortality Weekly Report. 65, 35, p. 943-944 2 p.

Research output: Contribution to journalComment/debate

Open Access
3 Scopus citations

The endothelial protein C receptor rs867186-GG genotype is associated with increased soluble EPCR and could mediate protection against severe malaria

Shabani, E., Opoka, R. O., Bangirana, P., Park, G. S., Vercellotti, G. M., Guan, W., Hodges, J. S., Lavstsen, T. & John, C. C., Jun 3 2016, In : Scientific reports. 6, 27084.

Research output: Contribution to journalArticle

8 Scopus citations