Find Publications

2019
1 Citation (Scopus)

Model-guided antipsychotic dose reduction in schizophrenia: A pilot, single-blind randomized controlled trial

Ozawa, C., Bies, R. R., Pillai, N., Suzuki, T., Mimura, M. & Uchida, H., Jul 1 2019, In : Journal of Clinical Psychopharmacology. 39, 4, p. 329-335 7 p.

Research output: Contribution to journalArticle

Antipsychotic Agents
Schizophrenia
olanzapine
Randomized Controlled Trials
Maintenance

Modelling survival

Zimmers, T. A. & Koniaris, L. G., Dec 10 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
Muscle Weakness
Muscle
Sepsis
Survival
2 Citations (Scopus)

Modulation of the Tryptophan Hydroxylase 1/Monoamine Oxidase-A/5-Hydroxytryptamine/5-Hydroxytryptamine Receptor 2A/2B/2C Axis Regulates Biliary Proliferation and Liver Fibrosis During Cholestasis

Kyritsi, K., Chen, L., O'Brien, A., Francis, H., Hein, T. W., Venter, J., Wu, N., Ceci, L., Zhou, T., Zawieja, D., Gashev, A. A., Meng, F., Invernizzi, P., Fabris, L., Wu, C., Skill, N. J., Saxena, R., Liangpunsakul, S., Alpini, G. & Glaser, S. S., Jan 1 2019, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Tryptophan Hydroxylase
Serotonin Receptors
Cholestasis
Monoamine Oxidase
Liver Cirrhosis

Molecular characterization and diagnostic criteria of renal cell carcinoma with emphasis on liquid biopsies

Cimadamore, A., Massari, F., Santoni, M., Mollica, V., Di Nunno, V., Cheng, L., Lopez-Beltran, A., Scarpelli, M., Montironi, R. & Moch, H., Jan 1 2019, (Accepted/In press) In : Expert Review of Molecular Diagnostics.

Research output: Contribution to journalReview article

Molecular Pathology
Renal Cell Carcinoma
Biopsy
Neoplasms
Long Noncoding RNA
1 Citation (Scopus)

Molecular characterization of testicular germ cell tumors: Chasing the underlying pathways

Chovanec, M. & Cheng, L., Jan 1 2019, In : Future Oncology. 15, 3, p. 227-229 3 p.

Research output: Contribution to journalEditorial

Testis
Molecular Biology
Biomarkers
Testicular Germ Cell Tumor

Molecular evidence supporting the precursor nature of atypical adenomatous hyperplasia of the prostate

Cheng, L., Montironi, R., Davidson, D., Wang, M., Lopez-Beltran, A. & Zhang, S., Jul 1 2019, In : Molecular Carcinogenesis. 58, 7, p. 1272-1278 7 p.

Research output: Contribution to journalArticle

Hyperplasia
Prostate
Telomere Shortening
Prostatic Intraepithelial Neoplasia
Adenocarcinoma
4 Citations (Scopus)

Molecular Mechanisms Responsible for the Rescue Effects of Pamidronate on Muscle Atrophy in Pediatric Burn Patients

Pin, F., Bonetto, A., Bonewald, L. F. & Klein, G. L., Aug 7 2019, In : Frontiers in Endocrinology. 10, 543.

Research output: Contribution to journalArticle

Open Access
pamidronate
Muscular Atrophy
Pediatrics
Serum
Skeletal Muscle Fibers

Molecular signaling in bone cells: Regulation of cell differentiation and survival

Plotkin, L. & Bruzzaniti, A., Jan 1 2019, Advances in Protein Chemistry and Structural Biology. Academic Press Inc., (Advances in Protein Chemistry and Structural Biology).

Research output: Chapter in Book/Report/Conference proceedingChapter

Osteoclasts
Osteoblasts
Cell Differentiation
Cell Survival
Bone
Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Mutation
Fluorescence In Situ Hybridization
Needles

Moon missions spark the human imagination

Lahiri, D. K., Nov 1 2019, In : Science. 366, 6465, 1 p.

Research output: Contribution to journalLetter

Astronauts
Imagination
Space Flight

MRI in acute pancreatitis

Sandrasegaran, K., Heller, M. T., Panda, A., Shetty, A. & Menias, C. O., Jan 1 2019, In : Abdominal Radiology.

Research output: Contribution to journalReview article

Pancreatitis
Tomography
Magnetic Resonance Imaging
Respiration

Multicenter, Prospective, Phase II and Biomarker Study of High-Dose Bevacizumab as Induction Therapy in Patients With Neurofibromatosis Type 2 and Progressive Vestibular Schwannoma

Plotkin, S. R., Duda, D. G., Muzikansky, A., Allen, J., Blakeley, J., Rosser, T., Campian, J. L., Clapp, D. W., Fisher, M. J., Tonsgard, J., Ullrich, N., Thomas, C., Cutter, G., Korf, B., Packer, R. & Karajannis, M. A., Dec 10 2019, In : Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 37, 35, p. 3446-3454 9 p.

Research output: Contribution to journalArticle

Neurofibromatosis 2
Acoustic Neuroma
Biomarkers
Hearing
Quality of Life

Multicenter clinical evaluation of the automated Aries Bordetella assay

Relich, R., Leber, A., Young, S., Schutzbank, T., Dunn, R., Farhang, J. & Uphoff, T. S., Feb 1 2019, In : Journal of clinical microbiology. 57, 2, e01471.

Research output: Contribution to journalArticle

Bordetella parapertussis
Bordetella
Bordetella pertussis
Bordetella Infections
Whooping Cough

Multicenter evaluation of NeuModx group B Streptococcus assay on the NeuModx 288 molecular system

Emery, C., Relich, R., Davis, T., Young, S. A., Sims, M. D. & Boyanton, B. L., Feb 1 2019, In : Journal of Clinical Microbiology. 57, 2, e01324.

Research output: Contribution to journalArticle

Streptococcus agalactiae
Confidence Intervals
Centers for Disease Control and Prevention (U.S.)
Meningitis
Developed Countries
3 Citations (Scopus)

Multicenter pre-operative assessment of pediatric ovarian malignancy

Madenci, A. L., Vandewalle, R. J., Dieffenbach, B. V., Laufer, M. R., Boyd, T. K., Voss, S. D., Frazier, A. L., Billmire, D. F., Rescorla, F., Weil, B. R. & Weldon, C. B., Jan 1 2019, In : Journal of Pediatric Surgery.

Research output: Contribution to journalArticle

Pediatrics
Neoplasms
Operative Surgical Procedures
Ovariectomy
Tumor Biomarkers

Multicystic adenomatoid hamartoma of the pancreas

Hosfield, B. D., Grayson, B. L., Nakeeb, A., Albright, E. A. & Markel, T. A., Sep 1 2019, In : Journal of Pediatric Surgery Case Reports. 48, 101258.

Research output: Contribution to journalArticle

Open Access
Hamartoma
Pancreas
Steatorrhea
Exocrine Pancreatic Insufficiency
Failure to Thrive

Multimodal action of MAS activation for systemic cancer cachexia therapy

Rupert, J. E., Koniaris, L. & Zimmers, T., Feb 15 2019, In : Cancer Research. 79, 4, p. 699-700 2 p.

Research output: Contribution to journalReview article

Cachexia
Neoplasms
Research
Muscle Cells
Skeletal Muscle

Multimodal Hippocampal Subfield Grading For Alzheimer’s Disease Classification

Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific reports. 9, 1, 13845.

Research output: Contribution to journalArticle

Open Access
Hippocampus
Alzheimer Disease
Biomarkers
Magnetic Resonance Imaging
Diffusion Magnetic Resonance Imaging

Multiobjective Calibration of Disease Simulation Models Using Gaussian Processes

Sai, A., Vivas-Valencia, C., Imperiale, T. & Kong, N., Jan 1 2019, (Accepted/In press) In : Medical Decision Making.

Research output: Contribution to journalArticle

Adenoma
Calibration
Natural History
Colorectal Neoplasms
Colon

Multiple functional variants in the IL1RL1 region are pretransplant markers for risk of GVHD and infection deaths

Karaesmen, E., Hahn, T., Dile, A. J., Rizvi, A. A., Wang, J., Wang, T., Haagenson, M. D., Preus, L., Zhu, Q., Liu, Q., Yan, L., Liu, S., Haiman, C. A., Stram, D., Pooler, L., Sheng, X., Van Den Berg, D., Brock, G., Webb, A., McCarthy, P. L. & 5 others, Pasquini, M. C., Spellman, S. R., Lee, S. J., Paczesny, S. & Sucheston-Campbell, L. E., Aug 27 2019, In : Blood Advances. 3, 16, p. 2512-2524 13 p.

Research output: Contribution to journalArticle

Open Access
Graft vs Host Disease
Tissue Donors
Cell Transplantation
Infection
Serum
8 Citations (Scopus)

Multi-site investigation of strategies for the clinical implementation of CYP2D6 genotyping to guide drug prescribing

on behalf of the IGNITE Network, Jan 1 2019, In : Genetics in Medicine.

Research output: Contribution to journalArticle

Drug Prescriptions
Cytochrome P-450 CYP2D6
Genotype
Clinical Decision Support Systems
Pharmacogenetics

Multi-staged regulation of lipid signaling mediators during myogenesis by COX-1/2 pathways

Mo, C., Wang, Z., Bonewald, L. & Brotto, M., Sep 2019, In : International journal of molecular sciences. 20, 18, 4326.

Research output: Contribution to journalArticle

Open Access
Cyclooxygenase 1
Muscle Development
Cyclooxygenase 2
Lipids
lipids

Music, Medicine, and Mind

Zyromski, N. J., Jan 1 2019, (Accepted/In press) In : American Journal of Surgery.

Research output: Contribution to journalArticle

Mutant huntingtin fails to directly impair brain mitochondria

Hamilton, J., Brustovetsky, T. & Brustovetsky, N., Jan 1 2019, (Accepted/In press) In : Journal of Neurochemistry.

Research output: Contribution to journalArticle

Mitochondria
Brain
Huntington Disease
Membrane Potentials
Reactive Oxygen Species

Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway

Chen, S., Wang, Q., Yu, H., Capitano, M. L., Vemula, S., Nabinger, S. C., Gao, R., Yao, C., Kobayashi, M., Geng, Z., Fahey, A., Henley, D., Liu, S. Z., Barajas, S., Cai, W., Wolf, E. R., Ramdas, B., Cai, Z., Gao, H., Luo, N. & 12 others, Sun, Y., Wong, T. N., Link, D. C., Liu, Y., Boswell, H. S., Mayo, L. D., Huang, G., Kapur, R., Yoder, M. C., Broxmeyer, H. E., Gao, Z. & Liu, Y., Dec 1 2019, In : Nature communications. 10, 1, 5649.

Research output: Contribution to journalArticle

Open Access
hematopoiesis
Hematopoiesis
Hematopoietic Stem Cells
Epigenomics
mutations
2 Citations (Scopus)

Mutant p53 enhances leukemia-initiating cell self-renewal to promote leukemia development

Nabinger, S. C., Chen, S., Gao, R., Yao, C., Kobayashi, M., Vemula, S., Fahey, A. C., Wang, C., Daniels, C., Boswell, H., Sandusky, G., Mayo, L., Kapur, R. & Liu, Y., Jan 1 2019, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Leukemia
Cell Self Renewal

MYB-NFIB gene fusion in prostatic basal cell carcinoma: clinicopathologic correlates and comparison with basal cell adenoma and florid basal cell hyperplasia

Magers, M. J., Iczkowski, K. A., Montironi, R., Grignon, D., Zhang, S., Williamson, S. R., Yang, X., Wang, M., Osunkoya, A. O., Lopez-Beltran, A., Hes, O., Eble, J. & Cheng, L., Jan 1 2019, In : Modern Pathology.

Research output: Contribution to journalArticle

Gene Fusion
Basal Cell Carcinoma
Adenoma
Adenoid Cystic Carcinoma
Hyperplasia

Myeloid-derived suppressor cells and pancreatic cancer: Implications in novel therapeutic approaches

Thyagarajan, A., Alshehri, M. S. A., Miller, K. L. R., Sherwin, C. M., Travers, J. B. & Sahu, R. P., Nov 2019, In : Cancers. 11, 11, 1627.

Research output: Contribution to journalReview article

Open Access
Pancreatic Neoplasms
Adenocarcinoma
Neoplasms
Immune Evasion
Therapeutics
2 Citations (Scopus)

Myofibroblast β2 adrenergic signaling amplifies cardiac hypertrophy in mice

Imaeda, A., Tanaka, S., Tonegawa, K., Fuchigami, S., Obana, M., Maeda, M., Kihara, M., Kiyonari, H., Conway, S., Fujio, Y. & Nakayama, H., Feb 26 2019, In : Biochemical and Biophysical Research Communications. 510, 1, p. 149-155 7 p.

Research output: Contribution to journalArticle

Myofibroblasts
Cardiomegaly
Adrenergic Agents
Adrenergic Receptors
Fibroblasts

Nanofibrous antibiotic-eluting matrices: Biocompatibility studies in a rat model

Passos, P. C., Moro, J., Barcelos, R. C. S., Da Rosa, H. Z., Vey, L. T., Bürguer, M. E., Maciel, R. M., Danesi, C. C., Edwards, P. C., Bottino, M. C. & Kantorski, K. Z., Jan 1 2019, In : Journal of Biomedical Materials Research - Part B Applied Biomaterials.

Research output: Contribution to journalArticle

Antibiotics
Biocompatibility
Collagen
Rats
Ciprofloxacin
10 Citations (Scopus)

Narrow-Band Imaging for Detection of Neoplasia at Colonoscopy: A Meta-analysis of Data From Individual Patients in Randomized Controlled Trials

Atkinson, N. S. S., Ket, S., Bassett, P., Aponte, D., De Aguiar, S., Gupta, N., Horimatsu, T., Ikematsu, H., Inoue, T., Kaltenbach, T., Leung, W. K., Matsuda, T., Paggi, S., Radaelli, F., Rastogi, A., Rex, D. K., Sabbagh, L. C., Saito, Y., Sano, Y., Saracco, G. M. & 6 others, Saunders, B. P., Senore, C., Soetikno, R., Vemulapalli, K. C., Jairath, V. & East, J. E., Aug 2019, In : Gastroenterology. 157, 2, p. 462-471 10 p.

Research output: Contribution to journalArticle

Narrow Band Imaging
Colonoscopy
Meta-Analysis
Endoscopy
Randomized Controlled Trials

National Cancer Institute Centers and Society of Surgical Oncology Cancer Research Synergy

Kim, B. J., Misra, S., Chen, H., Bell, T. M., Koniaris, L. & Valsangkar, N. P., Apr 1 2019, In : Journal of Surgical Research. 236, p. 92-100 9 p.

Research output: Contribution to journalArticle

National Cancer Institute (U.S.)
Research
Neoplasms
Publications
1 Citation (Scopus)

Natural History of Perinatal and Infantile Hypophosphatasia: A Retrospective Study

Study 011-10 Investigators, Jan 1 2019, In : Journal of Pediatrics.

Research output: Contribution to journalArticle

Natural History
Retrospective Studies
Hypophosphatasia
Vitamins
Reference Values

Neck circumference and cardiovascular outcomes: Insights from the Jackson Heart Study

Pumill, C. A., Bush, C. G., Greiner, M. A., Hall, M. E., Dunlay, S. M., Correa, A., Curtis, L. H., Suzuki, T., Hardy, C., Blackshear, C. T., O'Brien, E. C. & Mentz, R. J., Jun 2019, In : American Heart Journal. 212, p. 72-79 8 p.

Research output: Contribution to journalArticle

Neck
Hospitalization
Heart Failure
African Americans
Risk Adjustment
Open Access
Toxoplasma
Protein Transport
Vacuoles
Proteins
Molecular Biology

Neonate with red diaper

Wang, A. & Nanagas, K., Oct 1 2019, In : Emergency Medicine Journal. 36, 10, p. 594 and 634

Research output: Contribution to journalComment/debate

Emergency Medicine
Pediatric Emergency Medicine

Neurodegenerative Patterns of Cognitive Clusters of Early-Onset Alzheimer's Disease Subjects: Evidence for Disease Heterogeneity

Phillips, M. L., Stage, E. C., Lane, K. A., Gao, S., Risacher, S. L., Goukasian, N., Saykin, A. J., Carrillo, M. C., Dickerson, B. C., Rabinovici, G. D. & Apostolova, L. G., Jan 1 2019, (Accepted/In press) In : Dementia and Geriatric Cognitive Disorders.

Research output: Contribution to journalArticle

Neurodevelopmental Outcomes in Pre-School and School Aged Children with Biliary Atresia and their Native Liver

Squires, J. E., Ng, V. L., Hawthorne, K., Henn, L., Sorensen, L. G., Fredericks, E. M., Alonso, E. M., Murray, K. F., Loomes, K. M., Karpen, S. J., Cavallo, L. A., Molleston, J., Bezerra, J. A., Rosenthal, P., Squires, R. H., Wang, K. S., Schwarz, K. B., Arnon, R., Magee, J. C. & Sokol, R. J., Jan 1 2019, (Accepted/In press) In : Journal of pediatric gastroenterology and nutrition.

Research output: Contribution to journalArticle

Biliary Atresia
Intelligence
Liver
Portal Hypertension
Transferases

Neuroimaging in aging and neurologic diseases

Risacher, S. L. & Saykin, A. J., 2019, Handbook of Clinical Neurology. Elsevier B.V., p. 191-227 37 p. (Handbook of Clinical Neurology; vol. 167).

Research output: Chapter in Book/Report/Conference proceedingChapter

Nervous System Diseases
Neuroimaging
Dementia
Frontotemporal Dementia
Primary Progressive Nonfluent Aphasia
7 Citations (Scopus)

Neuropathological correlates and genetic architecture of microglial activation in elderly human brain

Felsky, D., Roostaei, T., Nho, K., Risacher, S. L., Bradshaw, E. M., Petyuk, V., Schneider, J. A., Saykin, A., Bennett, D. A. & De Jager, P. L., Dec 1 2019, In : Nature Communications. 10, 1, 409.

Research output: Contribution to journalArticle

Microglia
brain
Brain
proportion
Chemical activation

Neurosurgical Flexible Probe Microscopy with Enhanced Architectural and Cytological Detail

Osman, H., Elsahy, D., Slivova, V., Thompson, C., Georges, J., Yocom, S. & Cohen-Gadol, A., Jan 1 2019, In : World Neurosurgery.

Research output: Contribution to journalArticle

Neurosurgical Procedures
Microscopy
Oligodendroglioma
Acridine Orange
Meningioma
Methamphetamine
Dopaminergic Neurons
Alcohols
Drinking
Dopamine Plasma Membrane Transport Proteins
4 Citations (Scopus)

New and Recurrent Colorectal Cancers After Resection: a Systematic Review and Meta-analysis of Endoscopic Surveillance Studies

Fuccio, L., Rex, D., Ponchon, T., Frazzoni, L., Dinis-Ribeiro, M., Bhandari, P., Dekker, E., Pellisè, M., Correale, L., van Hooft, J., Jover, R., Libanio, D., Radaelli, F., Alfieri, S., Bazzoli, F., Senore, C., Regula, J., Seufferlein, T., Rösch, T., Sharma, P. & 2 others, Repici, A. & Hassan, C., Apr 1 2019, In : Gastroenterology. 156, 5, p. 1309-1323.e3

Research output: Contribution to journalArticle

Meta-Analysis
Colorectal Neoplasms
Confidence Intervals
Incidence
Colonoscopy
12 Citations (Scopus)

Niraparib monotherapy for late-line treatment of ovarian cancer (QUADRA): a multicentre, open-label, single-arm, phase 2 trial

Moore, K. N., Secord, A. A., Geller, M. A., Miller, D. S., Cloven, N., Fleming, G. F., Wahner Hendrickson, A. E., Azodi, M., DiSilvestro, P., Oza, A. M., Cristea, M., Berek, J. S., Chan, J. K., Rimel, B. J., Matei, D., Li, Y., Sun, K., Luptakova, K., Matulonis, U. A. & Monk, B. J., May 1 2019, In : The Lancet Oncology. 20, 5, p. 636-648 13 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Therapeutics
niraparib
Homologous Recombination
Platinum
5 Citations (Scopus)

No Gains in Long-term Survival After Liver Transplantation Over the Past Three Decades

Rana, A., Ackah, R. L., Webb, G. J., Halazun, K. J., Vierling, J. M., Liu, H., Wu, M. F., Yoeli, D., Kueht, M., Mindikoglu, A. L., Sussman, N. L., Galván, N. T., Cotton, R. T., O'Mahony, C. A. & Goss, J. A., Jan 1 2019, In : Annals of surgery. 269, 1, p. 20-27 8 p.

Research output: Contribution to journalArticle

Liver Transplantation
Survival
Immunosuppression
Transplants
Survivors
8 Citations (Scopus)

Nonalcoholic Fatty Liver Disease and the Heart: JACC State-of-the-Art Review

Stahl, E. P., Dhindsa, D. S., Lee, S. K., Sandesara, P. B., Chalasani, N. & Sperling, L. S., Mar 5 2019, In : Journal of the American College of Cardiology. 73, 8, p. 948-963 16 p.

Research output: Contribution to journalReview article

Cardiovascular Diseases
Cardiomyopathies
Lipid Metabolism
Insulin Resistance
Cardiac Arrhythmias
1 Citation (Scopus)

Non-coding variability at the APOE locus contributes to the Alzheimer’s risk

Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Nature communications. 10, 1, 3310.

Research output: Contribution to journalArticle

Open Access
loci
Alzheimer Disease
Haplotypes
Endophenotypes
brain
1 Citation (Scopus)

Nonlinear Z-score modeling for improved detection of cognitive abnormality

ARTFL/LEFFTDS consortium, Dec 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 797-808 12 p.

Research output: Contribution to journalArticle

Open Access
Sex Education

Non-obese histologically confirmed NASH patients with abnormal liver biochemistry have more advanced fibrosis

Wang, Q., You, H., Ou, X., Zhao, X., Sun, Y., Wang, M., Wang, P., Wang, Y., Duan, W., Wang, X., Wu, S., Kong, Y., Saxena, R., Gouw, A. S. H. & Jia, J., Jan 1 2019, (Accepted/In press) In : Hepatology International.

Research output: Contribution to journalArticle

Fatty Liver
Biochemistry
Fibrosis
Liver
Alleles

Nonparametric estimation of the cumulative incidence function under outcome misclassification using external validation data

Edwards, J. K., Bakoyannis, G., Yiannoutsos, C. T., Mburu, M. W. & Cole, S. R., Dec 20 2019, In : Statistics in Medicine. 38, 29, p. 5512-5527 16 p.

Research output: Contribution to journalArticle

Cumulative Incidence Function
Misclassification
Misclassification Probability
Nonparametric Estimation
Incidence