Find Publications

2019

MicroRNA-15a inhibits inflammatory response and apoptosis after spinal cord injury via targeting STAT3

Wu, W. D., Wang, L. H., Wei, N. X., Kong, D. H., Shao, G., Zhang, S. R. & Du, Y. S., Jan 1 2019, In : European Review for Medical and Pharmacological Sciences. 23, 21, p. 9189-9198 10 p.

Research output: Contribution to journalArticle

STAT3 Transcription Factor
MicroRNAs
Spinal Cord Injuries
Interleukin-6
Tumor Necrosis Factor-alpha
1 Citation (Scopus)

MicroRNA-196a is regulated by ER and is a prognostic biomarker in ER+ breast cancer

Milevskiy, M. J. G., Gujral, U., Del Lama Marques, C., Stone, A., Northwood, K., Burke, L. J., Gee, J. M. W., Nephew, K., Clark, S. & Brown, M. A., Jan 1 2019, In : British Journal of Cancer.

Research output: Contribution to journalArticle

MicroRNAs
Biomarkers
Breast Neoplasms
Annexins
Chromatin

MicroRNA 362-3p Reduces hERG-related Current and Inhibits Breast Cancer Cells Proliferation

Assiri, A. A., Mourad, N., Shao, M., Kiel, P., Liu, W., Skaar, T. C. & Overholser, B. R., Nov 1 2019, In : Cancer genomics & proteomics. 16, 6, p. 433-442 10 p.

Research output: Contribution to journalArticle

Open Access
Cell proliferation
MicroRNAs
Cell Proliferation
Breast Neoplasms
3' Untranslated Regions

MicroRNA410 Inhibits Pulmonary Vascular Remodeling via Regulation of Nicotinamide Phosphoribosyltransferase

Gao, H., Chen, J., Chen, T., Wang, Y., Song, Y., Dong, Y., Zhao, S. & Machado, R., Dec 1 2019, In : Scientific reports. 9, 1, 9949.

Research output: Contribution to journalArticle

Open Access
Nicotinamide Phosphoribosyltransferase
Lung
Pulmonary Hypertension
Pulmonary Artery
Endothelial Cells

MicroRNA 7 Impairs Insulin Signaling and Regulates Aβ Levels through Posttranscriptional Regulation of the Insulin Receptor Substrate 2, Insulin Receptor, Insulin-Degrading Enzyme, and Liver X Receptor Pathway

Fernández-de Frutos, M., Galán-Chilet, I., Goedeke, L., Kim, B., Pardo-Marqués, V., Pérez-García, A., Herrero, J. I., Fernández-Hernando, C., Kim, J. & Ramírez, C. M., Nov 15 2019, In : Molecular and cellular biology. 39, 22

Research output: Contribution to journalArticle

Insulysin
Insulin Receptor Substrate Proteins
Insulin Receptor
MicroRNAs
Insulin

Microsatellite Instability May Predict Response to Sipuleucel-T in Patients With Prostate Cancer

Zhang, K. J., Schneider, B. & Albany, C., Jan 1 2019, In : Clinical Genitourinary Cancer.

Research output: Contribution to journalArticle

Microsatellite Instability
Immunotherapy
Prostatic Neoplasms
sipuleucel-T
9 Citations (Scopus)

Mid-Term Valve-Related Outcomes After Transcatheter Tricuspid Valve-in-Valve or Valve-in-Ring Replacement

VIVID Registry, Jan 22 2019, In : Journal of the American College of Cardiology. 73, 2, p. 148-157 10 p.

Research output: Contribution to journalArticle

Tricuspid Valve
Endocarditis
Thrombosis
Surgical Instruments
Pulmonary Valve

MildInt: Deep learning-based multimodal longitudinal data integration framework

Lee, G., Kang, B., Nho, K., Sohn, K. A. & Kim, D., Jan 1 2019, In : Frontiers in Genetics. 10, JUN, 617.

Research output: Contribution to journalArticle

Open Access
Learning
Boidae
Linear Models
Neuroimaging
Disease Progression
1 Citation (Scopus)

Million-fold sensitivity enhancement in proteopathic seed amplification assays for biospecimens by Hofmeister ion comparisons

Metrick, M. A., do Carmo Ferreira, N., Saijo, E., Hughson, A. G., Kraus, A., Orrú, C., Miller, M. W., Zanusso, G., Ghetti, B., Vendruscolo, M. & Caughey, B., Nov 12 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 46, p. 23029-23039 11 p.

Research output: Contribution to journalArticle

Open Access
Proteostasis Deficiencies
Seeds
Prion Diseases
Prions
Ions

MIND food and speed of processing training in older adults with low education, the MINDSpeed Alzheimer's disease prevention pilot trial

Clark, D. O., Xu, H., Moser, L., Adeoye, P., Lin, A. W., Tangney, C. C., Risacher, S. L., Saykin, A. J., Considine, R. V. & Unverzagt, F. W., Sep 1 2019, In : Contemporary Clinical Trials. 84, 105814.

Research output: Contribution to journalArticle

Food Handling
Dementia
Alzheimer Disease
Cognitive Reserve
Education

Mindfulness Training Supports Quality of Life and Advance Care Planning in Adults With Metastatic Cancer and Their Caregivers: Results of a Pilot Study

Johns, S., Beck-Coon, K., Stutz, P. V., Talib, T. L., Chinh, K., Cottingham, A. H., Schmidt, K., Shields, C., Stout, M. E., Stump, T. E., Monahan, P., Torke, A. & Helft, P., Jan 1 2019, (Accepted/In press) In : American Journal of Hospice and Palliative Medicine.

Research output: Contribution to journalArticle

Advance Care Planning
Mindfulness
Training Support
Caregivers
Quality of Life
1 Citation (Scopus)

Mining regional imaging genetic associations via voxel-wise enrichment analysis

Yao, X., Cong, S., Yan, J., Risacher, S. L., Saykin, A. J., Moore, J. H. & Shen, L., May 2019, 2019 IEEE EMBS International Conference on Biomedical and Health Informatics, BHI 2019 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 8834450. (2019 IEEE EMBS International Conference on Biomedical and Health Informatics, BHI 2019 - Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Brain
Imaging techniques
Neuroimaging
Phenotype
Single Nucleotide Polymorphism

MiR322 mediates cardioprotection against ischemia/reperfusion injury via FBXW7/notch pathway

Chen, Z., Su, X., Shen, Y., Jin, Y., Luo, T., Kim, I. M., Weintraub, N. L. & Tang, Y., Aug 2019, In : Journal of Molecular and Cellular Cardiology. 133, p. 67-74 8 p.

Research output: Contribution to journalArticle

Reperfusion Injury
Myocardial Reperfusion
Myocardial Ischemia
Apoptosis
Cardiac Myocytes

MIRC11 disrupts inflammatory but not cytotoxic responses of NK cells

Nanbakhsh, A., Srinivasamani, A., Holzhauer, S., Riese, M. J., Zheng, Y., Wang, D., Burns, R., Reimer, M. H., Rao, S., Lemke, A., Tsaih, S. W., Flister, M. J., Lao, S., Dahl, R., Thakar, M. S. & Malarkannan, S., Jan 1 2019, In : Cancer Immunology Research. 7, 10, p. 1647-1662 16 p.

Research output: Contribution to journalArticle

MicroRNAs
Natural Killer Cells
TNF Receptor-Associated Factor 6
Cytokines
NF-kappa B

Missed opportunities! End of life decision making and discussions in implantable cardioverter defibrillator recipients

Miller, J. L., Chung, M. L., Etaee, F., Hammash, M., Thylén, I., Biddle, M. J., Elayi, S. C., Czarapata, M. M., McEvedy, S., Cameron, J., Haedtke, C., Ski, C. F., Thompson, D. R. & Moser, D. K., Jan 1 2019, In : Heart and Lung.

Research output: Contribution to journalArticle

Implantable Defibrillators
Decision Making
Active Euthanasia
Guideline Adherence
Terminal Care

Mission reconnect: Protocol for a mobile and web-based self-directed complementary and integrative health program for veterans and their partners

Haun, J. N., Ballistrea, L. M., Melillo, C., Standifer, M., Kip, K., Paykel, J., Murphy, J. L., Fletcher, C. E., Mitchinson, A., Kozak, L., Taylor, S. L., Glynn, S. M. & Bair, M., May 1 2019, In : Journal of medical Internet research. 21, 5, e13666.

Research output: Contribution to journalArticle

Open Access
Veterans Health
Veterans
Post-Traumatic Stress Disorders
Chronic Pain
Health

Mixed message on formula mixing

Wilkinson, T. A., Scott, E. K. & Carroll, A., Jan 1 2019, In : Pediatrics. 143, 6, e20182525.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Model-guided antipsychotic dose reduction in schizophrenia: A pilot, single-blind randomized controlled trial

Ozawa, C., Bies, R. R., Pillai, N., Suzuki, T., Mimura, M. & Uchida, H., Jul 1 2019, In : Journal of Clinical Psychopharmacology. 39, 4, p. 329-335 7 p.

Research output: Contribution to journalArticle

Antipsychotic Agents
Schizophrenia
olanzapine
Randomized Controlled Trials
Maintenance

Modelling survival

Zimmers, T. A. & Koniaris, L. G., Dec 10 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
Muscle Weakness
Muscle
Sepsis
Survival
2 Citations (Scopus)

Modulation of the Tryptophan Hydroxylase 1/Monoamine Oxidase-A/5-Hydroxytryptamine/5-Hydroxytryptamine Receptor 2A/2B/2C Axis Regulates Biliary Proliferation and Liver Fibrosis During Cholestasis

Kyritsi, K., Chen, L., O'Brien, A., Francis, H., Hein, T. W., Venter, J., Wu, N., Ceci, L., Zhou, T., Zawieja, D., Gashev, A. A., Meng, F., Invernizzi, P., Fabris, L., Wu, C., Skill, N. J., Saxena, R., Liangpunsakul, S., Alpini, G. & Glaser, S. S., Jan 1 2019, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Tryptophan Hydroxylase
Serotonin Receptors
Cholestasis
Monoamine Oxidase
Liver Cirrhosis

Molecular characterization and diagnostic criteria of renal cell carcinoma with emphasis on liquid biopsies

Cimadamore, A., Massari, F., Santoni, M., Mollica, V., Di Nunno, V., Cheng, L., Lopez-Beltran, A., Scarpelli, M., Montironi, R. & Moch, H., Jan 1 2019, (Accepted/In press) In : Expert Review of Molecular Diagnostics.

Research output: Contribution to journalReview article

Molecular Pathology
Renal Cell Carcinoma
Biopsy
Neoplasms
Long Noncoding RNA
1 Citation (Scopus)

Molecular characterization of testicular germ cell tumors: Chasing the underlying pathways

Chovanec, M. & Cheng, L., Jan 1 2019, In : Future Oncology. 15, 3, p. 227-229 3 p.

Research output: Contribution to journalEditorial

Testis
Molecular Biology
Biomarkers
Testicular Germ Cell Tumor

Molecular evidence supporting the precursor nature of atypical adenomatous hyperplasia of the prostate

Cheng, L., Montironi, R., Davidson, D., Wang, M., Lopez-Beltran, A. & Zhang, S., Jul 1 2019, In : Molecular Carcinogenesis. 58, 7, p. 1272-1278 7 p.

Research output: Contribution to journalArticle

Hyperplasia
Prostate
Telomere Shortening
Prostatic Intraepithelial Neoplasia
Adenocarcinoma
4 Citations (Scopus)

Molecular Mechanisms Responsible for the Rescue Effects of Pamidronate on Muscle Atrophy in Pediatric Burn Patients

Pin, F., Bonetto, A., Bonewald, L. F. & Klein, G. L., Aug 7 2019, In : Frontiers in Endocrinology. 10, 543.

Research output: Contribution to journalArticle

Open Access
pamidronate
Muscular Atrophy
Pediatrics
Serum
Skeletal Muscle Fibers

Molecular signaling in bone cells: Regulation of cell differentiation and survival

Plotkin, L. & Bruzzaniti, A., Jan 1 2019, Advances in Protein Chemistry and Structural Biology. Academic Press Inc., (Advances in Protein Chemistry and Structural Biology).

Research output: Chapter in Book/Report/Conference proceedingChapter

Osteoclasts
Osteoblasts
Cell Differentiation
Cell Survival
Bone
Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Mutation
Fluorescence In Situ Hybridization
Needles

Moon missions spark the human imagination

Lahiri, D. K., Nov 1 2019, In : Science. 366, 6465, 1 p.

Research output: Contribution to journalLetter

Astronauts
Imagination
Space Flight

MRI in acute pancreatitis

Sandrasegaran, K., Heller, M. T., Panda, A., Shetty, A. & Menias, C. O., Jan 1 2019, In : Abdominal Radiology.

Research output: Contribution to journalReview article

Pancreatitis
Tomography
Magnetic Resonance Imaging
Respiration

Multicenter, Prospective, Phase II and Biomarker Study of High-Dose Bevacizumab as Induction Therapy in Patients With Neurofibromatosis Type 2 and Progressive Vestibular Schwannoma

Plotkin, S. R., Duda, D. G., Muzikansky, A., Allen, J., Blakeley, J., Rosser, T., Campian, J. L., Clapp, D. W., Fisher, M. J., Tonsgard, J., Ullrich, N., Thomas, C., Cutter, G., Korf, B., Packer, R. & Karajannis, M. A., Dec 10 2019, In : Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 37, 35, p. 3446-3454 9 p.

Research output: Contribution to journalArticle

Neurofibromatosis 2
Acoustic Neuroma
Biomarkers
Hearing
Quality of Life

Multicenter clinical evaluation of the automated Aries Bordetella assay

Relich, R., Leber, A., Young, S., Schutzbank, T., Dunn, R., Farhang, J. & Uphoff, T. S., Feb 1 2019, In : Journal of clinical microbiology. 57, 2, e01471.

Research output: Contribution to journalArticle

Bordetella parapertussis
Bordetella
Bordetella pertussis
Bordetella Infections
Whooping Cough

Multicenter evaluation of NeuModx group B Streptococcus assay on the NeuModx 288 molecular system

Emery, C., Relich, R., Davis, T., Young, S. A., Sims, M. D. & Boyanton, B. L., Feb 1 2019, In : Journal of Clinical Microbiology. 57, 2, e01324.

Research output: Contribution to journalArticle

Streptococcus agalactiae
Confidence Intervals
Centers for Disease Control and Prevention (U.S.)
Meningitis
Developed Countries
3 Citations (Scopus)

Multicenter pre-operative assessment of pediatric ovarian malignancy

Madenci, A. L., Vandewalle, R. J., Dieffenbach, B. V., Laufer, M. R., Boyd, T. K., Voss, S. D., Frazier, A. L., Billmire, D. F., Rescorla, F., Weil, B. R. & Weldon, C. B., Jan 1 2019, In : Journal of Pediatric Surgery.

Research output: Contribution to journalArticle

Pediatrics
Neoplasms
Operative Surgical Procedures
Ovariectomy
Tumor Biomarkers

Multicystic adenomatoid hamartoma of the pancreas

Hosfield, B. D., Grayson, B. L., Nakeeb, A., Albright, E. A. & Markel, T. A., Sep 1 2019, In : Journal of Pediatric Surgery Case Reports. 48, 101258.

Research output: Contribution to journalArticle

Open Access
Hamartoma
Pancreas
Steatorrhea
Exocrine Pancreatic Insufficiency
Failure to Thrive

Multimodal action of MAS activation for systemic cancer cachexia therapy

Rupert, J. E., Koniaris, L. & Zimmers, T., Feb 15 2019, In : Cancer Research. 79, 4, p. 699-700 2 p.

Research output: Contribution to journalReview article

Cachexia
Neoplasms
Research
Muscle Cells
Skeletal Muscle

Multimodal Hippocampal Subfield Grading For Alzheimer’s Disease Classification

Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific reports. 9, 1, 13845.

Research output: Contribution to journalArticle

Open Access
Hippocampus
Alzheimer Disease
Biomarkers
Magnetic Resonance Imaging
Diffusion Magnetic Resonance Imaging

Multiobjective Calibration of Disease Simulation Models Using Gaussian Processes

Sai, A., Vivas-Valencia, C., Imperiale, T. & Kong, N., Jan 1 2019, (Accepted/In press) In : Medical Decision Making.

Research output: Contribution to journalArticle

Adenoma
Calibration
Natural History
Colorectal Neoplasms
Colon

Multiple functional variants in the IL1RL1 region are pretransplant markers for risk of GVHD and infection deaths

Karaesmen, E., Hahn, T., Dile, A. J., Rizvi, A. A., Wang, J., Wang, T., Haagenson, M. D., Preus, L., Zhu, Q., Liu, Q., Yan, L., Liu, S., Haiman, C. A., Stram, D., Pooler, L., Sheng, X., Van Den Berg, D., Brock, G., Webb, A., McCarthy, P. L. & 5 others, Pasquini, M. C., Spellman, S. R., Lee, S. J., Paczesny, S. & Sucheston-Campbell, L. E., Aug 27 2019, In : Blood Advances. 3, 16, p. 2512-2524 13 p.

Research output: Contribution to journalArticle

Open Access
Graft vs Host Disease
Tissue Donors
Cell Transplantation
Infection
Serum
8 Citations (Scopus)

Multi-site investigation of strategies for the clinical implementation of CYP2D6 genotyping to guide drug prescribing

on behalf of the IGNITE Network, Jan 1 2019, In : Genetics in Medicine.

Research output: Contribution to journalArticle

Drug Prescriptions
Cytochrome P-450 CYP2D6
Genotype
Clinical Decision Support Systems
Pharmacogenetics

Multi-staged regulation of lipid signaling mediators during myogenesis by COX-1/2 pathways

Mo, C., Wang, Z., Bonewald, L. & Brotto, M., Sep 2019, In : International journal of molecular sciences. 20, 18, 4326.

Research output: Contribution to journalArticle

Open Access
Cyclooxygenase 1
Muscle Development
Cyclooxygenase 2
Lipids
lipids

Music, Medicine, and Mind

Zyromski, N. J., Jan 1 2019, (Accepted/In press) In : American Journal of Surgery.

Research output: Contribution to journalArticle

Mutant huntingtin fails to directly impair brain mitochondria

Hamilton, J., Brustovetsky, T. & Brustovetsky, N., Jan 1 2019, (Accepted/In press) In : Journal of Neurochemistry.

Research output: Contribution to journalArticle

Mitochondria
Brain
Huntington Disease
Membrane Potentials
Reactive Oxygen Species

Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway

Chen, S., Wang, Q., Yu, H., Capitano, M. L., Vemula, S., Nabinger, S. C., Gao, R., Yao, C., Kobayashi, M., Geng, Z., Fahey, A., Henley, D., Liu, S. Z., Barajas, S., Cai, W., Wolf, E. R., Ramdas, B., Cai, Z., Gao, H., Luo, N. & 12 others, Sun, Y., Wong, T. N., Link, D. C., Liu, Y., Boswell, H. S., Mayo, L. D., Huang, G., Kapur, R., Yoder, M. C., Broxmeyer, H. E., Gao, Z. & Liu, Y., Dec 1 2019, In : Nature communications. 10, 1, 5649.

Research output: Contribution to journalArticle

Open Access
hematopoiesis
Hematopoiesis
Hematopoietic Stem Cells
Epigenomics
mutations
2 Citations (Scopus)

Mutant p53 enhances leukemia-initiating cell self-renewal to promote leukemia development

Nabinger, S. C., Chen, S., Gao, R., Yao, C., Kobayashi, M., Vemula, S., Fahey, A. C., Wang, C., Daniels, C., Boswell, H., Sandusky, G., Mayo, L., Kapur, R. & Liu, Y., Jan 1 2019, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Leukemia
Cell Self Renewal

MYB-NFIB gene fusion in prostatic basal cell carcinoma: clinicopathologic correlates and comparison with basal cell adenoma and florid basal cell hyperplasia

Magers, M. J., Iczkowski, K. A., Montironi, R., Grignon, D., Zhang, S., Williamson, S. R., Yang, X., Wang, M., Osunkoya, A. O., Lopez-Beltran, A., Hes, O., Eble, J. & Cheng, L., Jan 1 2019, In : Modern Pathology.

Research output: Contribution to journalArticle

Gene Fusion
Basal Cell Carcinoma
Adenoma
Adenoid Cystic Carcinoma
Hyperplasia

Myeloid-derived suppressor cells and pancreatic cancer: Implications in novel therapeutic approaches

Thyagarajan, A., Alshehri, M. S. A., Miller, K. L. R., Sherwin, C. M., Travers, J. B. & Sahu, R. P., Nov 2019, In : Cancers. 11, 11, 1627.

Research output: Contribution to journalReview article

Open Access
Pancreatic Neoplasms
Adenocarcinoma
Neoplasms
Immune Evasion
Therapeutics
2 Citations (Scopus)

Myofibroblast β2 adrenergic signaling amplifies cardiac hypertrophy in mice

Imaeda, A., Tanaka, S., Tonegawa, K., Fuchigami, S., Obana, M., Maeda, M., Kihara, M., Kiyonari, H., Conway, S., Fujio, Y. & Nakayama, H., Feb 26 2019, In : Biochemical and Biophysical Research Communications. 510, 1, p. 149-155 7 p.

Research output: Contribution to journalArticle

Myofibroblasts
Cardiomegaly
Adrenergic Agents
Adrenergic Receptors
Fibroblasts

Nanofibrous antibiotic-eluting matrices: Biocompatibility studies in a rat model

Passos, P. C., Moro, J., Barcelos, R. C. S., Da Rosa, H. Z., Vey, L. T., Bürguer, M. E., Maciel, R. M., Danesi, C. C., Edwards, P. C., Bottino, M. C. & Kantorski, K. Z., Jan 1 2019, In : Journal of Biomedical Materials Research - Part B Applied Biomaterials.

Research output: Contribution to journalArticle

Antibiotics
Biocompatibility
Collagen
Rats
Ciprofloxacin
10 Citations (Scopus)

Narrow-Band Imaging for Detection of Neoplasia at Colonoscopy: A Meta-analysis of Data From Individual Patients in Randomized Controlled Trials

Atkinson, N. S. S., Ket, S., Bassett, P., Aponte, D., De Aguiar, S., Gupta, N., Horimatsu, T., Ikematsu, H., Inoue, T., Kaltenbach, T., Leung, W. K., Matsuda, T., Paggi, S., Radaelli, F., Rastogi, A., Rex, D. K., Sabbagh, L. C., Saito, Y., Sano, Y., Saracco, G. M. & 6 others, Saunders, B. P., Senore, C., Soetikno, R., Vemulapalli, K. C., Jairath, V. & East, J. E., Aug 2019, In : Gastroenterology. 157, 2, p. 462-471 10 p.

Research output: Contribution to journalArticle

Narrow Band Imaging
Colonoscopy
Meta-Analysis
Endoscopy
Randomized Controlled Trials

National Cancer Institute Centers and Society of Surgical Oncology Cancer Research Synergy

Kim, B. J., Misra, S., Chen, H., Bell, T. M., Koniaris, L. & Valsangkar, N. P., Apr 1 2019, In : Journal of Surgical Research. 236, p. 92-100 9 p.

Research output: Contribution to journalArticle

National Cancer Institute (U.S.)
Research
Neoplasms
Publications
1 Citation (Scopus)

Natural History of Perinatal and Infantile Hypophosphatasia: A Retrospective Study

Study 011-10 Investigators, Jan 1 2019, In : Journal of Pediatrics.

Research output: Contribution to journalArticle

Natural History
Retrospective Studies
Hypophosphatasia
Vitamins
Reference Values