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  • Li Shen

2014 Update of the Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception

Alzheimer's Disease Neuroimaging Initiative, Jun 1 2015, In : Alzheimer's and Dementia. 11, 6, p. e1-e120

Research output: Contribution to journalArticle

154 Scopus citations

Accelerating sparse canonical correlation analysis for large brain imaging genetics data

Yan, J., Zhang, H., Du, L., Wernert, E., Saykin, A. J. & Shen, L., Jan 1 2014, Proceedings of the XSEDE 2014 Conference: Engaging Communities. Association for Computing Machinery, 4. (ACM International Conference Proceeding Series).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

A dirty multi-task learning method for multi-modal brain imaging genetics

for the Alzheimer’s Disease Neuroimaging Initiative, Jan 1 2019, Medical Image Computing and Computer Assisted Intervention – MICCAI 2019 - 22nd International Conference, Proceedings. Shen, D., Yap, P-T., Liu, T., Peters, T. M., Khan, A., Staib, L. H., Essert, C. & Zhou, S. (eds.). Springer, p. 447-455 9 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11767 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

A fast SCCA algorithm for big data analysis in brain imaging genetics

Alzheimer’s Disease Neuroimaging Initiative, 2017, Graphs in Biomedical Image Analysis, Computational Anatomy and Imaging Genetics - 1st International Workshop, GRAIL 2017 6th International Workshop, MFCA 2017 and 3rd International Workshop, MICGen 2017 Held in Conjunction with MICCAI 2017, Proceedings. Springer Verlag, Vol. 10551 LNCS. p. 210-219 10 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10551 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

A graph-based integration of multimodal brain imaging data for the detection of early mild cognitive impairment (E-MCI)

Kim, D., Kim, S., Risacher, S. L., Shen, L., Ritchie, M. D., Weiner, M. W., Saykin, A. J. & Nho, K., 2013, Multimodal Brain Image Analysis - Third International Workshop, MBIA 2013, Held in Conjunction with MICCAI 2013, Proceedings. p. 159-169 11 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 8159 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Scopus citations

A large scale multivariate parallel ICA method reveals novel imaging-genetic relationships for Alzheimer's disease in the ADNI cohort

Meda, S. A., Narayanan, B., Liu, J., Perrone-Bizzozero, N. I., Stevens, M. C., Calhoun, V. D., Glahn, D. C., Shen, L., Risacher, S. L., Saykin, A. J. & Pearlson, G. D., Apr 15 2012, In : NeuroImage. 60, 3, p. 1608-1621 14 p.

Research output: Contribution to journalArticle

80 Scopus citations

A Mixture Dose-Response Model for Identifying High-Dimensional Drug Interaction Effects on Myopathy Using Electronic Medical Record Databases

Zhang, P., Du, L., Wang, L., Liu, M., Cheng, L., Chiang, C. W., Wu, H. Y., Quinney, S. K., Shen, L. & Li, L., Aug 1 2015, In : CPT: Pharmacometrics and Systems Pharmacology. 4, 8, p. 474-480 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

A multi-model deep convolutional neural network for automatic hippocampus segmentation and classification in Alzheimer's disease

Liu, M., Li, F., Yan, H., Wang, K., Ma, Y., Shen, L. & Xu, M., Mar 2020, In : NeuroImage. 208, 116459.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Amyloid pathway-based candidate gene analysis of [ 11 C]PiB-PET in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort

Swaminathan, S., Shen, L., Risacher, S. L., Yoder, K. K., West, J. D., Kim, S., Nho, K., Foroud, T., Inlow, M., Potkin, S. G., Huentelman, M. J., Craig, D. W., Jagust, W. J., Koeppe, R. A., Mathis, C. A., Jack, C. R., Weiner, M. W. & Saykin, A. J., Mar 2012, In : Brain Imaging and Behavior. 6, 1, p. 1-15 15 p.

Research output: Contribution to journalArticle

30 Scopus citations

Analysis of copy number variation in Alzheimer's disease: The NIALOAD/ NCRAD family study

Swaminathan, S., Shen, L., Kim, S., Inlow, M., West, J. D., Faber, K. M., Foroud, T., Mayeux, R. & Saykin, A. J., 2012, In : Current Alzheimer research. 9, 7, p. 801-814 14 p.

Research output: Contribution to journalReview article

44 Scopus citations

Analysis of Copy Number Variation in Alzheimer's Disease in a Cohort of Clinically Characterized and Neuropathologically Verified Individuals

Swaminathan, S., Huentelman, M. J., Corneveaux, J. J., Myers, A. J., Faber, K. M., Foroud, T., Mayeux, R., Shen, L., Kim, S., Turk, M., Hardy, J., Reiman, E. M. & Saykin, A. J., Dec 5 2012, In : PloS one. 7, 12, e50640.

Research output: Contribution to journalArticle

26 Scopus citations

A Network-Based Framework for Mining High-Level Imaging Genetic Associations

Liang, H., Meng, X., Chen, F., Zhang, Q., Yan, J., Yao, X., Kim, S., Wang, L., Feng, W., Saykin, A. J., Li, J. & Shen, L., Jan 1 2018, Imaging Genetics. Elsevier Inc., p. 119-134 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

A new sparse simplex model for brain anatomical and genetic network analysis

Huang, H., Yan, J., Nie, F., Huang, J., Cai, W., Saykin, A. J. & Shen, L., Oct 24 2013, Medical Image Computing and Computer-Assisted Intervention, MICCAI 2013 - 16th International Conference, Proceedings. PART 2 ed. p. 625-632 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 8150 LNCS, no. PART 2).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Scopus citations

A new statistical image analysis approach and its application to Hippocampal morphometry

ADNI, 2016, Medical Imaging and Augmented Reality - 7th International Conference, MIAR 2016, Proceedings. Liao, H., Zheng, G., Lee, S-L., Cattin, P. & Jannin, P. (eds.). Springer Verlag, p. 302-310 9 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 9805 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

A Novel Joint Brain Network Analysis Using Longitudinal Alzheimer’s Disease Data

The Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific reports. 9, 1, 19589.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

A novel SCCA approach via truncated â.," 1-norm and truncated group lasso for brain imaging genetics

Du, L., Liu, K., Zhang, T., Yao, X., Yan, J., Risacher, S. L., Han, J., Guo, L., Saykin, A. J. & Shen, L., Jan 15 2018, In : Bioinformatics. 34, 2, p. 278-285 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

A novel structure-aware sparse learning algorithm for brain imaging genetics

Du, L., Yan, J., Kim, S., Risacher, S. L., Huang, H., Inlow, M., Moore, J. H., Saykin, A. J. & Shen, L., 2014, Medical Image Computing and Computer-Assisted Intervention, MICCAI 2014 - 17th International Conference, Proceedings. PART 3 ed. Springer Verlag, p. 329-336 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 8675 LNCS, no. PART 3).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

24 Scopus citations

APOE and BCHE as modulators of cerebral amyloid deposition: A florbetapir PET genome-wide association study

Ramanan, V. K., Risacher, S. L., Nho, K., Kim, S., Swaminathan, S., Shen, L., Foroud, T. M., Hakonarson, H., Huentelman, M. J., Aisen, P. S., Petersen, R. C., Green, R. C., Jack, C. R., Koeppe, R. A., Jagust, W. J., Weiner, M. W. & Saykin, A. J., Mar 1 2014, In : Molecular Psychiatry. 19, 3, p. 351-357 7 p.

Research output: Contribution to journalArticle

119 Scopus citations

APOE effect on Alzheimer's disease biomarkers in older adults with significant memory concern

Risacher, S. L., Kim, S., Nho, K., Foroud, T., Shen, L., Petersen, R. C., Jack, C. R., Beckett, L. A., Aisen, P. S., Koeppe, R. A., Jagust, W. J., Shaw, L. M., Trojanowski, J. Q., Weiner, M. W., Saykin, A. J. & Alzheimer's Disease Neuroimaging Initiative (ADNI), D. N. I. ADNI., Dec 1 2015, In : Alzheimer's and Dementia. 11, 12, p. 1417-1429 13 p.

Research output: Contribution to journalArticle

81 Scopus citations

A Review of Statistical-learning Imaging Genetics

Hao, X. K., Li, C. X., Yan, J. W., Shen, L. & Zhang, D. Q., Jan 2018, In : Zidonghua Xuebao/Acta Automatica Sinica. 44, 1, p. 13-24 12 p.

Research output: Contribution to journalReview article

Association analysis of rare variants near the APOE region with CSF and neuroimaging biomarkers of Alzheimer’s disease

Nho, K., Kim, S., Horgusluoglu, E., Risacher, S. L., Shen, L., Kim, D., Lee, S., Foroud, T., Shaw, L. M., Trojanowski, J. Q., Aisen, P. S., Petersen, R. C., Jack, C. R., Weiner, M. W., Green, R. C., Toga, A. W. & Saykin, A. J., May 24 2017, In : BMC Medical Genomics. 10, 29.

Research output: Contribution to journalArticle

9 Scopus citations

Association between anticholinergic medication use and cognition, brain metabolism, and brain atrophy in cognitively normal older adults

Alzheimer's Disease Neuroimaging Initiative, Jun 2016, In : JAMA Neurology. 73, 6, p. 721-732 12 p.

Research output: Contribution to journalArticle

107 Scopus citations

Association of plasma and cortical amyloid beta is modulated by APOE ε4 status

Swaminathan, S., Risacher, S. L., Yoder, K. K., West, J. D., Shen, L., Kim, S., Inlow, M., Foroud, T., Jagust, W. J., Koeppe, R. A., Mathis, C. A., Shaw, L. M., Trojanowski, J. Q., Soares, H., Aisen, P. S., Petersen, R. C., Weiner, M. W. & Saykin, A. J., Jan 2014, In : Alzheimer's and Dementia. 10, 1, p. e9-e18

Research output: Contribution to journalArticle

26 Scopus citations

Association of plasma neurofilament light with neurodegeneration in patients with Alzheimer disease

Alzheimer's Disease Neuroimaging Initiative, May 2017, In : JAMA Neurology. 74, 5, p. 557-566 10 p.

Research output: Contribution to journalArticle

214 Scopus citations

A super-combo-drug test to detect adverse drug events and drug interactions from electronic health records in the era of polypharmacy

Zhu, A., Zeng, D., Shen, L., Ning, X., Li, L. & Zhang, P., May 15 2020, In : Statistics in Medicine. 39, 10, p. 1458-1472 15 p.

Research output: Contribution to journalArticle

A unified model for joint normalization and differential gene expression detection in RNA-seq data

Liu, K., Ye, J., Yang, Y., Shen, L. & Jiang, H., Mar 1 2019, In : IEEE/ACM Transactions on Computational Biology and Bioinformatics. 16, 2, p. 442-454 13 p., 8249873.

Research output: Contribution to journalArticle

4 Scopus citations

A Unified Model for Robust Differential Expression Analysis of RNA-Seq Data

Liu, K., Shen, L. & Jian, H., Jan 21 2019, Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018. Schmidt, H., Griol, D., Wang, H., Baumbach, J., Zheng, H., Callejas, Z., Hu, X., Dickerson, J. & Zhang, L. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 437-442 6 p. 8621331. (Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

BECA: A Software Tool for Integrated Visualization of Human Brain Data

Li, H., Fang, S., Zigon, B., Sporns, O., Saykin, A. J., Goñi, J. & Shen, L., Jan 1 2017, Brain Informatics - International Conference, BI 2017, Proceedings. Zeng, Y., Xu, B., Martone, M., He, Y., Peng, H., Luo, Q. & Kotaleski, J. H. (eds.). Springer Verlag, p. 285-291 7 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10654 LNAI).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Bootstrapped Sparse Canonical Correlation Analysis: Mining Stable Imaging and Genetic Associations With Implicit Structure Learning. Mining Stable Imaging and Genetic Associations With Implicit Structure Learning.

Yan, J., Du, L., Kim, S., Risacher, S. L., Huang, H., Inlow, M., Moore, J. H., Saykin, A. J. & Shen, L., Jan 1 2018, Imaging Genetics. Elsevier Inc., p. 101-117 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Brain explorer for connectomic analysis

for the Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2017, In : Brain Informatics. 4, 4, p. 253-269 17 p.

Research output: Contribution to journalArticle

1 Scopus citations

Brain Imaging Genomics: Integrated Analysis and Machine Learning

Shen, L. & Thompson, P. M., Jan 2020, In : Proceedings of the IEEE. 108, 1, p. 125-162 38 p., 8886705.

Research output: Contribution to journalArticle

Brain-wide structural connectivity alterations under the control of Alzheimer risk genes

Yan, J., Vinesh Raja, V., Huang, Z., Amico, E., Nho, K., Fang, S., Sporns, O., Wu, Y. C., Saykin, A., Goñi, J. & Shen, L., 2020, In : International Journal of Computational Biology and Drug Design. 13, 1, p. 58-70 13 p.

Research output: Contribution to journalArticle

Building a surface atlas of hippocampal subfields from high resolution T2-weighted MRI scans using landmark-free surface registration

Cong, S., Rizkalla, M., Salama, P., Risacher, S. L., West, J. D., Wu, Y. C., Apostolova, L., Tallman, E., Saykin, A. J. & Shen, L., Jul 2 2016, 2016 IEEE 59th International Midwest Symposium on Circuits and Systems, MWSCAS 2016. Institute of Electrical and Electronics Engineers Inc., 7870109. (Midwest Symposium on Circuits and Systems; vol. 0).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Building a surface atlas of hippocampal subfields from MRI scans using FreeSurfer, FIRST and SPHARM

Cong, S., Rizkalla, M., Du, E. Y., West, J., Risacher, S., Saykin, A. & Shen, L., Sep 23 2014, 2014 IEEE 57th International Midwest Symposium on Circuits and Systems, MWSCAS 2014. Institute of Electrical and Electronics Engineers Inc., p. 813-816 4 p. 6908539. (Midwest Symposium on Circuits and Systems).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

9 Scopus citations

Characteristic patterns of inter- and intra-hemispheric metabolic connectivity in patients with stable and progressive mild cognitive impairment and Alzheimer’s disease

for the Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2018, In : Scientific reports. 8, 1, 13807.

Research output: Contribution to journalArticle

4 Scopus citations

Common genetic variants influence human subcortical brain structures

Hibar, D. P., Stein, J. L., Renteria, M. E., Arias-Vasquez, A., Desrivières, S., Jahanshad, N., Toro, R., Wittfeld, K., Abramovic, L., Andersson, M., Aribisala, B. S., Armstrong, N. J., Bernard, M., Bohlken, M. M., Boks, M. P., Bralten, J., Brown, A. A., Mallar Chakravarty, M., Chen, Q., Ching, C. R. K. & 267 others, Cuellar-Partida, G., Den Braber, A., Giddaluru, S., Goldman, A. L., Grimm, O., Guadalupe, T., Hass, J., Woldehawariat, G., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Olde Loohuis, L. M., Luciano, M., MacAre, C., Mather, K. A., Mattheisen, M., Milaneschi, Y., Nho, K., Papmeyer, M., Ramasamy, A., Risacher, S. L., Roiz-Santiañez, R., Rose, E. J., Salami, A., Sämann, P. G., Schmaal, L., Schork, A. J., Shin, J., Strike, L. T., Teumer, A., Van Donkelaar, M. M. J., Van Eijk, K. R., Walters, R. K., Westlye, L. T., Whelan, C. D., Winkler, A. M., Zwiers, M. P., Alhusaini, S., Athanasiu, L., Ehrlich, S., Hakobjan, M. M. H., Hartberg, C. B., Haukvik, U. K., Heister, A. J. G. A. M., Hoehn, D., Kasperaviciute, D., Liewald, D. C. M., Lopez, L. M., Makkinje, R. R. R., Matarin, M., Naber, M. A. M., Reese McKay, D., Needham, M., Nugent, A. C., Pütz, B., Royle, N. A., Shen, L., Sprooten, E., Trabzuni, D., Van Der Marel, S. S. L., Van Hulzen, K. J. E., Walton, E., Wolf, C., Almasy, L., Ames, D., Arepalli, S., Assareh, A. A., Bastin, M. E., Brodaty, H., Bulayeva, K. B., Carless, M. A., Cichon, S., Corvin, A., Curran, J. E., Czisch, M., De Zubicaray, G. I., Dillman, A., Duggirala, R., Dyer, T. D., Erk, S., Fedko, I. O., Ferrucci, L., Foroud, T. M., Fox, P. T., Fukunaga, M., Raphael Gibbs, J., Göring, H. H. H., Green, R. C., Guelfi, S., Hansell, N. K., Hartman, C. A., Hegenscheid, K., Heinz, A., Hernandez, D. G., Heslenfeld, D. J., Hoekstra, P. J., Holsboer, F., Homuth, G., Hottenga, J. J., Ikeda, M., Jack, C. R., Jenkinson, M., Johnson, R., Kanai, R., Keil, M., Kent, J. W., Kochunov, P., Kwok, J. B., Lawrie, S. M., Liu, X., Longo, D. L., McMahon, K. L., Meisenzahl, E., Melle, I., Mohnke, S., Montgomery, G. W., Mostert, J. C., Mühleisen, T. W., Nalls, M. A., Nichols, T. E., Nilsson, L. G., Nöthen, M. M., Ohi, K., Olvera, R. L., Perez-Iglesias, R., Bruce Pike, G., Potkin, S. G., Reinvang, I., Reppermund, S., Rietschel, M., Romanczuk-Seiferth, N., Rosen, G. D., Rujescu, D., Schnell, K., Schofield, P. R., Smith, C., Steen, V. M., Sussmann, J. E., Thalamuthu, A., Toga, A. W., Traynor, B. J., Troncoso, J., Turner, J. A., Valdés Hernández, M. C., Van 'T Ent, D., Van Der Brug, M., Van Der Wee, N. J. A., Van Tol, M. J., Veltman, D. J., Wassink, T. H., Westman, E., Zielke, R. H., Zonderman, A. B., Ashbrook, D. G., Hager, R., Lu, L., McMahon, F. J., Morris, D. W., Williams, R. W., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Cahn, W., Calhoun, V. D., Cavalleri, G. L., Crespo-Facorro, B., Dale, A. M., Davies, G. E., Delanty, N., Depondt, C., Djurovic, S., Drevets, W. C., Espeseth, T., Gollub, R. L., Ho, B. C., Hoffmann, W., Hosten, N., Kahn, R. S., Le Hellard, S., Meyer-Lindenberg, A., Müller-Myhsok, B., Nauck, M., Nyberg, L., Pandolfo, M., Penninx, B. W. J. H., Roffman, J. L., Sisodiya, S. M., Smoller, J. W., Van Bokhoven, H., Van Haren, N. E. M., Völzke, H., Walter, H., Weiner, M. W., Wen, W., White, T., Agartz, I., Andreassen, O. A., Blangero, J., Boomsma, D. I., Brouwer, R. M., Cannon, D. M., Cookson, M. R., De Geus, E. J. C., Deary, I. J., Donohoe, G., Fernández, G., Fisher, S. E., Francks, C., Glahn, D. C., Grabe, H. J., Gruber, O., Hardy, J., Hashimoto, R., Hulshoff Pol, H. E., Jönsson, E. G., Kloszewska, I., Lovestone, S., Mattay, V. S., Mecocci, P., McDonald, C., McIntosh, A. M., Ophoff, R. A., Paus, T., Pausova, Z., Ryten, M., Sachdev, P. S., Saykin, A. J., Simmons, A., Singleton, A., Soininen, H., Wardlaw, J. M., Weale, M. E., Weinberger, D. R., Adams, H. H. H., Launer, L. J., Seiler, S., Schmidt, R., Chauhan, G., Satizabal, C. L., Becker, J. T., Yanek, L., Van Der Lee, S. J., Ebling, M., Fischl, B., Longstreth, W. T., Greve, D., Schmidt, H., Nyquist, P., Vinke, L. N., Van Duijn, C. M., Xue, L., Mazoyer, B., Bis, J. C., Gudnason, V., Seshadri, S., Ikram, M. A., Martin, N. G., Wright, M. J., Schumann, G., Franke, B., Thompson, P. M. & Medland, S. E., Apr 9 2015, In : Nature. 520, 7546, p. 224-229 6 p.

Research output: Contribution to journalArticle

416 Scopus citations

Computational genetics analysis of grey matter density in Alzheimer's disease

Zieselman, A. L., Fisher, J. M., Hu, T., Andrews, P. C., Greene, C. S., Shen, L., Saykin, A. J. & Moore, J. H., Aug 22 2014, In : BioData Mining. 7, 1, 17.

Research output: Contribution to journalArticle

5 Scopus citations

Computed tomography assessment of peripubertal craniofacial morphology in a sheep model of binge alcohol drinking in the first trimester

Birch, S. M., Lenox, M. W., Kornegay, J. N., Shen, L., Ai, H., Ren, X., Goodlett, C. R., Cudd, T. A. & Washburn, S. E., Mar 2 2015, In : Alcohol. 49, 7, p. 675-689 15 p.

Research output: Contribution to journalArticle

2 Scopus citations

Cortical surface biomarkers for predicting cognitive outcomes using group l2,1 norm

Alzheimer's Disease Neuroimaging Initiative, Jan 1 2015, In : Neurobiology of Aging. 36, S1, p. S185-S193

Research output: Contribution to journalArticle

25 Scopus citations

Data synthesis and method evaluation for brain imaging genetics

Sheng, J., Kim, S., Yan, J., Moore, J., Saykin, A. & Shen, L., Jul 29 2014, 2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014. Institute of Electrical and Electronics Engineers Inc., p. 1202-1205 4 p. 6868091. (2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Scopus citations

Deep Network-Based Feature Selection for Imaging Genetics: Application to Identifying Biomarkers for Parkinson's Disease

Kim, M., Won, J. H., Hong, J., Kwon, J., Park, H. & Shen, L., Apr 2020, ISBI 2020 - 2020 IEEE International Symposium on Biomedical Imaging. IEEE Computer Society, p. 1920-1923 4 p. 9098471. (Proceedings - International Symposium on Biomedical Imaging; vol. 2020-April).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Detecting genetic associations with brain imaging phenotypes in Alzheimer's disease via a novel structured SCCA approach

Du, L., Liu, K., Yao, X., Risacher, S. L., Han, J., Saykin, A. J., Guo, L. & Shen, L., Apr 2020, In : Medical Image Analysis. 61, 101656.

Research output: Contribution to journalArticle

1 Scopus citations

Development of refractive error in individual children with regressed retinopathy of prematurity

Wang, J., Ren, X., Shen, L., Yanni, S. E., Leffler, J. N. & Birch, E. E., 2013, In : Investigative Ophthalmology and Visual Science. 54, 9, p. 6018-6024 7 p.

Research output: Contribution to journalArticle

39 Scopus citations

Diagnosis-guided method for identifying multi-modality neuroimaging biomarkers associated with genetic risk factors in Alzheimer’s disease

Hao, X., Yan, J., Yao, X., Risacher, S. L., Saykin, A. J., Zhang, D. & Shen, L., Jan 1 2016, In : Pacific Symposium on Biocomputing. p. 108-119 12 p.

Research output: Contribution to journalConference article

3 Scopus citations

Diagnosis status guided brain imaging genetics via integrated regression and sparse canonical correlation analysis

Du, L., Liu, K., Yao, X., Risacher, S. L., Guo, L., Saykin, A. J. & Shen, L., Apr 2019, ISBI 2019 - 2019 IEEE International Symposium on Biomedical Imaging. IEEE Computer Society, p. 356-359 4 p. 8759489. (Proceedings - International Symposium on Biomedical Imaging; vol. 2019-April).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Diffeomorphic Metric Learning and Template Optimization for Registration-Based Predictive Models

Mussabayeva, A., Pisov, M., Kurmukov, A., Kroshnin, A., Denisova, Y., Shen, L., Cong, S., Wang, L. & Gutman, B., Jan 1 2019, Multimodal Brain Image Analysis and Mathematical Foundations of Computational Anatomy - 4th International Workshop, MBIA 2019, and 7th International Workshop, MFCA 2019, Held in Conjunction with MICCAI 2019, Proceedings. Zhu, D., Yan, J., Huang, H., Shen, L., Thompson, P. M., Westin, C-F., Pennec, X., Joshi, S., Nielsen, M., Sommer, S., Fletcher, T. & Durrleman, S. (eds.). Springer, p. 151-161 11 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11846 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Drug-drug interaction prediction based on co-medication patterns and graph matching

Chiang, W. H., Shen, L., Li, L. & Ning, X., 2020, In : International Journal of Computational Biology and Drug Design. 13, 1, p. 36-57 22 p.

Research output: Contribution to journalArticle

Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis

The Alzheimer's Disease Neuroimaging Initiative, Jun 21 2016, In : Nature communications. 7, 11934.

Research output: Contribution to journalArticle

301 Scopus citations

Effect of prenatal alcohol exposure on bony craniofacial development: A mouse MicroCT study

Shen, L., Ai, H., Liang, Y., Ren, X., Anthony, C. B., Goodlett, C. R., Ward, R. & Zhou, F. C., Aug 2013, In : Alcohol. 47, 5, p. 405-415 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide

Thompson, P. M., Dennis, E. L., Gutman, B. A., Hibar, D. P., Jahanshad, N., Kelly, S., Stein, J. L., Whelan, C. D., Andreassen, O. A., Arias-Vasquez, A., Bearden, C. E., Boedhoe, P. S., van den Heuvel, O. L., Veltman, D. J., Brouwer, R. M., de Reus, M. A., Pol, H. E. H., van den Heuvel, M. P., Buckner, R. L., Buitelaar, J. K. & 51 others, Fisher, S. E., Francks, C., Franke, B., Hoogman, M., van Rooij, D., Bulayeva, K. B., Cannon, D. M., McDonald, C., Cohen, R. A., Conrod, P. J., Dale, A. M., Holland, D., Deary, I. J., Wardlaw, J. M., Desrivieres, S., Schumann, G., Dima, D., Frangou, S., Donohoe, G., Guadalupe, T., Fouche, J. P., Stein, D. J., Ganjgahi, H., Garavan, H., Glahn, D. C., Grabe, H. J., Hashimoto, R., Hosten, N., Kochunov, P., Kremen, W. S., Lee, P. H., Mackey, S., Mazoyer, B., Martin, N. G., Medland, S. E., Morey, R. A., Nichols, T. E., Paus, T., Pausova, Z., Shen, L., Sisodiya, S. M., Smit, D. J. A., Smoller, J. W., Toro, R., Turner, J. A., Schmaal, L., van Erp, T. G. M., Walter, H., Wang, Y., Wright, M. J. & Ye, J., Jan 15 2017, In : NeuroImage. 145, p. 389-408 20 p.

Research output: Contribution to journalArticle

84 Scopus citations