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  • Li Shen
Article

2014 Update of the Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception

Alzheimer's Disease Neuroimaging Initiative, Jun 1 2015, In : Alzheimer's and Dementia. 11, 6, p. e1-e120

Research output: Contribution to journalArticle

154 Scopus citations

A large scale multivariate parallel ICA method reveals novel imaging-genetic relationships for Alzheimer's disease in the ADNI cohort

Meda, S. A., Narayanan, B., Liu, J., Perrone-Bizzozero, N. I., Stevens, M. C., Calhoun, V. D., Glahn, D. C., Shen, L., Risacher, S. L., Saykin, A. J. & Pearlson, G. D., Apr 15 2012, In : NeuroImage. 60, 3, p. 1608-1621 14 p.

Research output: Contribution to journalArticle

80 Scopus citations

A Mixture Dose-Response Model for Identifying High-Dimensional Drug Interaction Effects on Myopathy Using Electronic Medical Record Databases

Zhang, P., Du, L., Wang, L., Liu, M., Cheng, L., Chiang, C. W., Wu, H. Y., Quinney, S. K., Shen, L. & Li, L., Aug 1 2015, In : CPT: Pharmacometrics and Systems Pharmacology. 4, 8, p. 474-480 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

A multi-model deep convolutional neural network for automatic hippocampus segmentation and classification in Alzheimer's disease

Liu, M., Li, F., Yan, H., Wang, K., Ma, Y., Shen, L. & Xu, M., Mar 2020, In : NeuroImage. 208, 116459.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Amyloid pathway-based candidate gene analysis of [ 11 C]PiB-PET in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort

Swaminathan, S., Shen, L., Risacher, S. L., Yoder, K. K., West, J. D., Kim, S., Nho, K., Foroud, T., Inlow, M., Potkin, S. G., Huentelman, M. J., Craig, D. W., Jagust, W. J., Koeppe, R. A., Mathis, C. A., Jack, C. R., Weiner, M. W. & Saykin, A. J., Mar 2012, In : Brain Imaging and Behavior. 6, 1, p. 1-15 15 p.

Research output: Contribution to journalArticle

30 Scopus citations

Analysis of Copy Number Variation in Alzheimer's Disease in a Cohort of Clinically Characterized and Neuropathologically Verified Individuals

Swaminathan, S., Huentelman, M. J., Corneveaux, J. J., Myers, A. J., Faber, K. M., Foroud, T., Mayeux, R., Shen, L., Kim, S., Turk, M., Hardy, J., Reiman, E. M. & Saykin, A. J., Dec 5 2012, In : PloS one. 7, 12, e50640.

Research output: Contribution to journalArticle

26 Scopus citations

A Novel Joint Brain Network Analysis Using Longitudinal Alzheimer’s Disease Data

The Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific reports. 9, 1, 19589.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

A novel SCCA approach via truncated â.," 1-norm and truncated group lasso for brain imaging genetics

Du, L., Liu, K., Zhang, T., Yao, X., Yan, J., Risacher, S. L., Han, J., Guo, L., Saykin, A. J. & Shen, L., Jan 15 2018, In : Bioinformatics. 34, 2, p. 278-285 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

APOE and BCHE as modulators of cerebral amyloid deposition: A florbetapir PET genome-wide association study

Ramanan, V. K., Risacher, S. L., Nho, K., Kim, S., Swaminathan, S., Shen, L., Foroud, T. M., Hakonarson, H., Huentelman, M. J., Aisen, P. S., Petersen, R. C., Green, R. C., Jack, C. R., Koeppe, R. A., Jagust, W. J., Weiner, M. W. & Saykin, A. J., Mar 1 2014, In : Molecular Psychiatry. 19, 3, p. 351-357 7 p.

Research output: Contribution to journalArticle

119 Scopus citations

APOE effect on Alzheimer's disease biomarkers in older adults with significant memory concern

Risacher, S. L., Kim, S., Nho, K., Foroud, T., Shen, L., Petersen, R. C., Jack, C. R., Beckett, L. A., Aisen, P. S., Koeppe, R. A., Jagust, W. J., Shaw, L. M., Trojanowski, J. Q., Weiner, M. W., Saykin, A. J. & Alzheimer's Disease Neuroimaging Initiative (ADNI), D. N. I. ADNI., Dec 1 2015, In : Alzheimer's and Dementia. 11, 12, p. 1417-1429 13 p.

Research output: Contribution to journalArticle

81 Scopus citations

Association analysis of rare variants near the APOE region with CSF and neuroimaging biomarkers of Alzheimer’s disease

Nho, K., Kim, S., Horgusluoglu, E., Risacher, S. L., Shen, L., Kim, D., Lee, S., Foroud, T., Shaw, L. M., Trojanowski, J. Q., Aisen, P. S., Petersen, R. C., Jack, C. R., Weiner, M. W., Green, R. C., Toga, A. W. & Saykin, A. J., May 24 2017, In : BMC Medical Genomics. 10, 29.

Research output: Contribution to journalArticle

9 Scopus citations

Association between anticholinergic medication use and cognition, brain metabolism, and brain atrophy in cognitively normal older adults

Alzheimer's Disease Neuroimaging Initiative, Jun 2016, In : JAMA Neurology. 73, 6, p. 721-732 12 p.

Research output: Contribution to journalArticle

107 Scopus citations

Association of plasma and cortical amyloid beta is modulated by APOE ε4 status

Swaminathan, S., Risacher, S. L., Yoder, K. K., West, J. D., Shen, L., Kim, S., Inlow, M., Foroud, T., Jagust, W. J., Koeppe, R. A., Mathis, C. A., Shaw, L. M., Trojanowski, J. Q., Soares, H., Aisen, P. S., Petersen, R. C., Weiner, M. W. & Saykin, A. J., Jan 2014, In : Alzheimer's and Dementia. 10, 1, p. e9-e18

Research output: Contribution to journalArticle

26 Scopus citations

Association of plasma neurofilament light with neurodegeneration in patients with Alzheimer disease

Alzheimer's Disease Neuroimaging Initiative, May 2017, In : JAMA Neurology. 74, 5, p. 557-566 10 p.

Research output: Contribution to journalArticle

214 Scopus citations

A super-combo-drug test to detect adverse drug events and drug interactions from electronic health records in the era of polypharmacy

Zhu, A., Zeng, D., Shen, L., Ning, X., Li, L. & Zhang, P., May 15 2020, In : Statistics in Medicine. 39, 10, p. 1458-1472 15 p.

Research output: Contribution to journalArticle

A unified model for joint normalization and differential gene expression detection in RNA-seq data

Liu, K., Ye, J., Yang, Y., Shen, L. & Jiang, H., Mar 1 2019, In : IEEE/ACM Transactions on Computational Biology and Bioinformatics. 16, 2, p. 442-454 13 p., 8249873.

Research output: Contribution to journalArticle

4 Scopus citations

Brain explorer for connectomic analysis

for the Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2017, In : Brain Informatics. 4, 4, p. 253-269 17 p.

Research output: Contribution to journalArticle

1 Scopus citations

Brain Imaging Genomics: Integrated Analysis and Machine Learning

Shen, L. & Thompson, P. M., Jan 2020, In : Proceedings of the IEEE. 108, 1, p. 125-162 38 p., 8886705.

Research output: Contribution to journalArticle

Brain-wide structural connectivity alterations under the control of Alzheimer risk genes

Yan, J., Vinesh Raja, V., Huang, Z., Amico, E., Nho, K., Fang, S., Sporns, O., Wu, Y. C., Saykin, A., Goñi, J. & Shen, L., 2020, In : International Journal of Computational Biology and Drug Design. 13, 1, p. 58-70 13 p.

Research output: Contribution to journalArticle

Characteristic patterns of inter- and intra-hemispheric metabolic connectivity in patients with stable and progressive mild cognitive impairment and Alzheimer’s disease

for the Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2018, In : Scientific reports. 8, 1, 13807.

Research output: Contribution to journalArticle

4 Scopus citations

Common genetic variants influence human subcortical brain structures

Hibar, D. P., Stein, J. L., Renteria, M. E., Arias-Vasquez, A., Desrivières, S., Jahanshad, N., Toro, R., Wittfeld, K., Abramovic, L., Andersson, M., Aribisala, B. S., Armstrong, N. J., Bernard, M., Bohlken, M. M., Boks, M. P., Bralten, J., Brown, A. A., Mallar Chakravarty, M., Chen, Q., Ching, C. R. K. & 267 others, Cuellar-Partida, G., Den Braber, A., Giddaluru, S., Goldman, A. L., Grimm, O., Guadalupe, T., Hass, J., Woldehawariat, G., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Olde Loohuis, L. M., Luciano, M., MacAre, C., Mather, K. A., Mattheisen, M., Milaneschi, Y., Nho, K., Papmeyer, M., Ramasamy, A., Risacher, S. L., Roiz-Santiañez, R., Rose, E. J., Salami, A., Sämann, P. G., Schmaal, L., Schork, A. J., Shin, J., Strike, L. T., Teumer, A., Van Donkelaar, M. M. J., Van Eijk, K. R., Walters, R. K., Westlye, L. T., Whelan, C. D., Winkler, A. M., Zwiers, M. P., Alhusaini, S., Athanasiu, L., Ehrlich, S., Hakobjan, M. M. H., Hartberg, C. B., Haukvik, U. K., Heister, A. J. G. A. M., Hoehn, D., Kasperaviciute, D., Liewald, D. C. M., Lopez, L. M., Makkinje, R. R. R., Matarin, M., Naber, M. A. M., Reese McKay, D., Needham, M., Nugent, A. C., Pütz, B., Royle, N. A., Shen, L., Sprooten, E., Trabzuni, D., Van Der Marel, S. S. L., Van Hulzen, K. J. E., Walton, E., Wolf, C., Almasy, L., Ames, D., Arepalli, S., Assareh, A. A., Bastin, M. E., Brodaty, H., Bulayeva, K. B., Carless, M. A., Cichon, S., Corvin, A., Curran, J. E., Czisch, M., De Zubicaray, G. I., Dillman, A., Duggirala, R., Dyer, T. D., Erk, S., Fedko, I. O., Ferrucci, L., Foroud, T. M., Fox, P. T., Fukunaga, M., Raphael Gibbs, J., Göring, H. H. H., Green, R. C., Guelfi, S., Hansell, N. K., Hartman, C. A., Hegenscheid, K., Heinz, A., Hernandez, D. G., Heslenfeld, D. J., Hoekstra, P. J., Holsboer, F., Homuth, G., Hottenga, J. J., Ikeda, M., Jack, C. R., Jenkinson, M., Johnson, R., Kanai, R., Keil, M., Kent, J. W., Kochunov, P., Kwok, J. B., Lawrie, S. M., Liu, X., Longo, D. L., McMahon, K. L., Meisenzahl, E., Melle, I., Mohnke, S., Montgomery, G. W., Mostert, J. C., Mühleisen, T. W., Nalls, M. A., Nichols, T. E., Nilsson, L. G., Nöthen, M. M., Ohi, K., Olvera, R. L., Perez-Iglesias, R., Bruce Pike, G., Potkin, S. G., Reinvang, I., Reppermund, S., Rietschel, M., Romanczuk-Seiferth, N., Rosen, G. D., Rujescu, D., Schnell, K., Schofield, P. R., Smith, C., Steen, V. M., Sussmann, J. E., Thalamuthu, A., Toga, A. W., Traynor, B. J., Troncoso, J., Turner, J. A., Valdés Hernández, M. C., Van 'T Ent, D., Van Der Brug, M., Van Der Wee, N. J. A., Van Tol, M. J., Veltman, D. J., Wassink, T. H., Westman, E., Zielke, R. H., Zonderman, A. B., Ashbrook, D. G., Hager, R., Lu, L., McMahon, F. J., Morris, D. W., Williams, R. W., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Cahn, W., Calhoun, V. D., Cavalleri, G. L., Crespo-Facorro, B., Dale, A. M., Davies, G. E., Delanty, N., Depondt, C., Djurovic, S., Drevets, W. C., Espeseth, T., Gollub, R. L., Ho, B. C., Hoffmann, W., Hosten, N., Kahn, R. S., Le Hellard, S., Meyer-Lindenberg, A., Müller-Myhsok, B., Nauck, M., Nyberg, L., Pandolfo, M., Penninx, B. W. J. H., Roffman, J. L., Sisodiya, S. M., Smoller, J. W., Van Bokhoven, H., Van Haren, N. E. M., Völzke, H., Walter, H., Weiner, M. W., Wen, W., White, T., Agartz, I., Andreassen, O. A., Blangero, J., Boomsma, D. I., Brouwer, R. M., Cannon, D. M., Cookson, M. R., De Geus, E. J. C., Deary, I. J., Donohoe, G., Fernández, G., Fisher, S. E., Francks, C., Glahn, D. C., Grabe, H. J., Gruber, O., Hardy, J., Hashimoto, R., Hulshoff Pol, H. E., Jönsson, E. G., Kloszewska, I., Lovestone, S., Mattay, V. S., Mecocci, P., McDonald, C., McIntosh, A. M., Ophoff, R. A., Paus, T., Pausova, Z., Ryten, M., Sachdev, P. S., Saykin, A. J., Simmons, A., Singleton, A., Soininen, H., Wardlaw, J. M., Weale, M. E., Weinberger, D. R., Adams, H. H. H., Launer, L. J., Seiler, S., Schmidt, R., Chauhan, G., Satizabal, C. L., Becker, J. T., Yanek, L., Van Der Lee, S. J., Ebling, M., Fischl, B., Longstreth, W. T., Greve, D., Schmidt, H., Nyquist, P., Vinke, L. N., Van Duijn, C. M., Xue, L., Mazoyer, B., Bis, J. C., Gudnason, V., Seshadri, S., Ikram, M. A., Martin, N. G., Wright, M. J., Schumann, G., Franke, B., Thompson, P. M. & Medland, S. E., Apr 9 2015, In : Nature. 520, 7546, p. 224-229 6 p.

Research output: Contribution to journalArticle

416 Scopus citations

Computational genetics analysis of grey matter density in Alzheimer's disease

Zieselman, A. L., Fisher, J. M., Hu, T., Andrews, P. C., Greene, C. S., Shen, L., Saykin, A. J. & Moore, J. H., Aug 22 2014, In : BioData Mining. 7, 1, 17.

Research output: Contribution to journalArticle

5 Scopus citations

Computed tomography assessment of peripubertal craniofacial morphology in a sheep model of binge alcohol drinking in the first trimester

Birch, S. M., Lenox, M. W., Kornegay, J. N., Shen, L., Ai, H., Ren, X., Goodlett, C. R., Cudd, T. A. & Washburn, S. E., Mar 2 2015, In : Alcohol. 49, 7, p. 675-689 15 p.

Research output: Contribution to journalArticle

2 Scopus citations

Cortical surface biomarkers for predicting cognitive outcomes using group l2,1 norm

Alzheimer's Disease Neuroimaging Initiative, Jan 1 2015, In : Neurobiology of Aging. 36, S1, p. S185-S193

Research output: Contribution to journalArticle

25 Scopus citations

Detecting genetic associations with brain imaging phenotypes in Alzheimer's disease via a novel structured SCCA approach

Du, L., Liu, K., Yao, X., Risacher, S. L., Han, J., Saykin, A. J., Guo, L. & Shen, L., Apr 2020, In : Medical Image Analysis. 61, 101656.

Research output: Contribution to journalArticle

1 Scopus citations

Development of refractive error in individual children with regressed retinopathy of prematurity

Wang, J., Ren, X., Shen, L., Yanni, S. E., Leffler, J. N. & Birch, E. E., 2013, In : Investigative Ophthalmology and Visual Science. 54, 9, p. 6018-6024 7 p.

Research output: Contribution to journalArticle

39 Scopus citations

Drug-drug interaction prediction based on co-medication patterns and graph matching

Chiang, W. H., Shen, L., Li, L. & Ning, X., 2020, In : International Journal of Computational Biology and Drug Design. 13, 1, p. 36-57 22 p.

Research output: Contribution to journalArticle

Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis

The Alzheimer's Disease Neuroimaging Initiative, Jun 21 2016, In : Nature communications. 7, 11934.

Research output: Contribution to journalArticle

301 Scopus citations

Effect of prenatal alcohol exposure on bony craniofacial development: A mouse MicroCT study

Shen, L., Ai, H., Liang, Y., Ren, X., Anthony, C. B., Goodlett, C. R., Ward, R. & Zhou, F. C., Aug 2013, In : Alcohol. 47, 5, p. 405-415 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide

Thompson, P. M., Dennis, E. L., Gutman, B. A., Hibar, D. P., Jahanshad, N., Kelly, S., Stein, J. L., Whelan, C. D., Andreassen, O. A., Arias-Vasquez, A., Bearden, C. E., Boedhoe, P. S., van den Heuvel, O. L., Veltman, D. J., Brouwer, R. M., de Reus, M. A., Pol, H. E. H., van den Heuvel, M. P., Buckner, R. L., Buitelaar, J. K. & 51 others, Fisher, S. E., Francks, C., Franke, B., Hoogman, M., van Rooij, D., Bulayeva, K. B., Cannon, D. M., McDonald, C., Cohen, R. A., Conrod, P. J., Dale, A. M., Holland, D., Deary, I. J., Wardlaw, J. M., Desrivieres, S., Schumann, G., Dima, D., Frangou, S., Donohoe, G., Guadalupe, T., Fouche, J. P., Stein, D. J., Ganjgahi, H., Garavan, H., Glahn, D. C., Grabe, H. J., Hashimoto, R., Hosten, N., Kochunov, P., Kremen, W. S., Lee, P. H., Mackey, S., Mazoyer, B., Martin, N. G., Medland, S. E., Morey, R. A., Nichols, T. E., Paus, T., Pausova, Z., Shen, L., Sisodiya, S. M., Smit, D. J. A., Smoller, J. W., Toro, R., Turner, J. A., Schmaal, L., van Erp, T. G. M., Walter, H., Wang, Y., Wright, M. J. & Ye, J., Jan 15 2017, In : NeuroImage. 145, p. 389-408 20 p.

Research output: Contribution to journalArticle

84 Scopus citations

FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease

The Alzheimer Disease Neuroimaging Initiative, Dec 1 2020, In : Nature communications. 11, 1, 411.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

FASTKD2 is associated with memory and hippocampal structure in older adults

Ramanan, V. K., Nho, K., Shen, L., Risacher, S. L., Kim, S., McDonald, B. C., Farlow, M. R., Foroud, T. M., Gao, S., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., Aisen, P. S., Petersen, R. C., Jack, C. R., Shaw, L. M., Trojanowski, J. Q. & 7 others, Weiner, M. W., Green, R. C., Toga, A. W., De Jager, P. L., Yu, L., Bennett, D. A. & Saykin, A. J., Oct 29 2015, In : Molecular Psychiatry. 20, 10, p. 1197-1204 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE

Alzheimer's Disease Neuroimaging Initiative, May 19 2015, In : Nature communications. 6, 6760.

Research output: Contribution to journalArticle

118 Scopus citations

From phenotype to genotype: An association study of longitudinal phenotypic markers to alzheimer's disease relevant SNPs

Wang, H., Nie, F., Huang, H., Yan, J., Kim, S., Nho, K., Risacher, S. L., Saykin, A. J. & Shen, L., Sep 2012, In : Bioinformatics. 28, 18, p. i619-i625 bts411.

Research output: Contribution to journalArticle

38 Scopus citations

Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease

Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dec 1 2020, In : Nature communications. 11, 1, 347.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Genetic analysis of quantitative phenotypes in AD and MCI: Imaging, cognition and biomarkers

Shen, L., Thompson, P. M., Potkin, S. G., Bertram, L., Farrer, L. A., Foroud, T. M., Green, R. C., Hu, X., Huentelman, M. J., Kim, S., Kauwe, J. S. K., Li, Q., Liu, E., Macciardi, F., Moore, J. H., Munsie, L., Nho, K., Ramanan, V. K., Risacher, S. L., Stone, D. J. & 4 others, Swaminathan, S., Toga, A. W., Weiner, M. W. & Saykin, A. J., Jun 2014, In : Brain Imaging and Behavior. 8, 2, p. 183-207 25 p.

Research output: Contribution to journalArticle

87 Scopus citations

Genetic architecture of subcortical brain structures in 38,851 individuals

Satizabal, C. L., Adams, H. H. H., Hibar, D. P., White, C. C., Knol, M. J., Stein, J. L., Scholz, M., Sargurupremraj, M., Jahanshad, N., Roshchupkin, G. V., Smith, A. V., Bis, J. C., Jian, X., Luciano, M., Hofer, E., Teumer, A., van der Lee, S. J., Yang, J., Yanek, L. R., Lee, T. V. & 269 others, Li, S., Hu, Y., Koh, J. Y., Eicher, J. D., Desrivières, S., Arias-Vasquez, A., Chauhan, G., Athanasiu, L., Rentería, M. E., Kim, S., Hoehn, D., Armstrong, N. J., Chen, Q., Holmes, A. J., den Braber, A., Kloszewska, I., Andersson, M., Espeseth, T., Grimm, O., Abramovic, L., Alhusaini, S., Milaneschi, Y., Papmeyer, M., Axelsson, T., Ehrlich, S., Roiz-Santiañez, R., Kraemer, B., Håberg, A. K., Jones, H. J., Pike, G. B., Stein, D. J., Stevens, A., Bralten, J., Vernooij, M. W., Harris, T. B., Filippi, I., Witte, A. V., Guadalupe, T., Wittfeld, K., Mosley, T. H., Becker, J. T., Doan, N. T., Hagenaars, S. P., Saba, Y., Cuellar-Partida, G., Amin, N., Hilal, S., Nho, K., Mirza-Schreiber, N., Arfanakis, K., Becker, D. M., Ames, D., Goldman, A. L., Lee, P. H., Boomsma, D. I., Lovestone, S., Giddaluru, S., Le Hellard, S., Mattheisen, M., Bohlken, M. M., Kasperaviciute, D., Schmaal, L., Lawrie, S. M., Agartz, I., Walton, E., Tordesillas-Gutierrez, D., Davies, G. E., Shin, J., Ipser, J. C., Vinke, L. N., Hoogman, M., Jia, T., Burkhardt, R., Klein, M., Crivello, F., Janowitz, D., Carmichael, O., Haukvik, U. K., Aribisala, B. S., Schmidt, H., Strike, L. T., Cheng, C. Y., Risacher, S. L., Pütz, B., Fleischman, D. A., Assareh, A. A., Mattay, V. S., Buckner, R. L., Mecocci, P., Dale, A. M., Cichon, S., Boks, M. P., Matarin, M., Penninx, B. W. J. H., Calhoun, V. D., Chakravarty, M. M., Marquand, A. F., Macare, C., Kharabian Masouleh, S., Oosterlaan, J., Amouyel, P., Hegenscheid, K., Rotter, J. I., Schork, A. J., Liewald, D. C. M., de Zubicaray, G. I., Wong, T. Y., Shen, L., Sämann, P. G., Brodaty, H., Roffman, J. L., de Geus, E. J. C., Tsolaki, M., Erk, S., van Eijk, K. R., Cavalleri, G. L., van der Wee, N. J. A., McIntosh, A. M., Gollub, R. L., Bulayeva, K. B., Bernard, M., Richards, J. S., Himali, J. J., Loeffler, M., Rommelse, N., Hoffmann, W., Westlye, L. T., Valdés Hernández, M. C., Hansell, N. K., van Erp, T. G. M., Wolf, C., Kwok, J. B. J., Vellas, B., Heinz, A., Olde Loohuis, L. M., Delanty, N., Ho, B. C., Ching, C. R. K., Shumskaya, E., Singh, B., Hofman, A., van der Meer, D., Homuth, G., Psaty, B. M., Bastin, M. E., Montgomery, G. W., Foroud, T. M., Reppermund, S., Hottenga, J. J., Simmons, A., Meyer-Lindenberg, A., Cahn, W., Whelan, C. D., van Donkelaar, M. M. J., Yang, Q., Hosten, N., Green, R. C., Thalamuthu, A., Mohnke, S., Hulshoff Pol, H. E., Lin, H., Jack, C. R., Schofield, P. R., Mühleisen, T. W., Maillard, P., Potkin, S. G., Wen, W., Fletcher, E., Toga, A. W., Gruber, O., Huentelman, M., Davey Smith, G., Launer, L. J., Nyberg, L., Jönsson, E. G., Crespo-Facorro, B., Koen, N., Greve, D. N., Uitterlinden, A. G., Weinberger, D. R., Steen, V. M., Fedko, I. O., Groenewold, N. A., Niessen, W. J., Toro, R., Tzourio, C., Longstreth, W. T., Ikram, M. K., Smoller, J. W., van Tol, M. J., Sussmann, J. E., Paus, T., Lemaître, H., Schroeter, M. L., Mazoyer, B., Andreassen, O. A., Holsboer, F., Depondt, C., Veltman, D. J., Turner, J. A., Pausova, Z., Schumann, G., van Rooij, D., Djurovic, S., Deary, I. J., McMahon, K. L., Müller-Myhsok, B., Brouwer, R. M., Soininen, H., Pandolfo, M., Wassink, T. H., Cheung, J. W., Wolfers, T., Martinot, J. L., Zwiers, M. P., Nauck, M., Melle, I., Martin, N. G., Kanai, R., Westman, E., Kahn, R. S., Sisodiya, S. M., White, T., Saremi, A., van Bokhoven, H., Brunner, H. G., Völzke, H., Wright, M. J., van ‘t Ent, D., Nöthen, M. M., Ophoff, R. A., Buitelaar, J. K., Fernández, G., Sachdev, P. S., Rietschel, M., van Haren, N. E. M., Fisher, S. E., Beiser, A. S., Francks, C., Saykin, A., Mather, K. A., Romanczuk-Seiferth, N., Hartman, C. A., DeStefano, A. L., Heslenfeld, D. J., Weiner, M. W., Walter, H., Hoekstra, P. J., Nyquist, P. A., Franke, B., Bennett, D. A., Grabe, H. J., Johnson, A. D., Chen, C., van Duijn, C. M., Lopez, O. L., Fornage, M., Wardlaw, J. M., Schmidt, R., DeCarli, C., De Jager, P. L., Villringer, A., Debette, S., Gudnason, V., Medland, S. E., Shulman, J. M., Thompson, P. M., Seshadri, S. & Ikram, M. A., Nov 1 2019, In : Nature genetics. 51, 11, p. 1624-1636 13 p.

Research output: Contribution to journalArticle

20 Scopus citations

Genetic influences on schizophrenia and subcortical brain volumes: Large-scale proof of concept

Psychosis Endophenotypes International Consortium, Feb 23 2016, In : Nature Neuroscience. 19, 3, p. 420-431 12 p.

Research output: Contribution to journalArticle

118 Scopus citations

Genetic Interactions Explain Variance in Cingulate Amyloid Burden: An AV-45 PET Genome-Wide Association and Interaction Study in the ADNI Cohort

Li, J., Zhang, Q., Chen, F., Yan, J., Kim, S., Wang, L., Feng, W., Saykin, A. J., Liang, H. & Shen, L., 2015, In : BioMed research international. 2015, 647389.

Research output: Contribution to journalArticle

16 Scopus citations

Genome-wide association and interaction studies of CSF T-tau/Aβ42 ratio in ADNI cohort

Li, J., Zhang, Q., Chen, F., Meng, X., Liu, W., Chen, D., Yan, J., Kim, S., Wang, L., Feng, W., Saykin, A. J., Liang, H. & Shen, L., Sep 2017, In : Neurobiology of Aging. 57, p. 247.e1-247.e8

Research output: Contribution to journalArticle

12 Scopus citations

Genome-wide association study of CSF biomarkers Aβ1-42, t-tau, and p-tau181p in the ADNI cohort

Kim, S., Swaminathan, S., Shen, L., Risacher, S. L., Nho, K., Foroud, T., Shaw, L. M., Trojanowski, J. Q., Potkin, S. G., Huentelman, M. J., Craig, D. W., Dechairo, B. M., Aisen, P. S., Petersen, R. C., Weiner, M. W. & Saykin, A. J., Jan 4 2011, In : Neurology. 76, 1, p. 69-79 11 p.

Research output: Contribution to journalArticle

137 Scopus citations

Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease

Furney, S. J., Simmons, A., Breen, G., Pedroso, I., Lunnon, K., Proitsi, P., Hodges, A., Powell, J., Wahlund, L. O., Kloszewska, I., Mecocci, P., Soininen, H., Tsolaki, M., Vellas, B., Spenger, C., Lathrop, M., Shen, L., Kim, S., Saykin, A. J., Weiner, M. W. & 1 others, Lovestone, S., Nov 2011, In : Molecular Psychiatry. 16, 11, p. 1130-1138 9 p.

Research output: Contribution to journalArticle

90 Scopus citations

Genome-wide network-assisted association and enrichment study of amyloid imaging phenotype in alzheimer’s disease

Alzheimer’s Disease Neuroimaging Initiative, Jan 1 2019, In : Current Alzheimer research. 16, 13, p. 1163-1174 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Genome-wide network-based pathway analysis of CSF t-tau/Aβ1-42 ratio in the ADNI cohort

for the Alzheimer's Disease Neuroimaging Initiative, May 30 2017, In : BMC genomics. 18, 1, 421.

Research output: Contribution to journalArticle

6 Scopus citations

Genome-wide pathway analysis of memory impairment in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort implicates gene candidates, canonical pathways, and networks

Ramanan, V. K., Kim, S., Holohan, K., Shen, L., Nho, K., Risacher, S. L., Foroud, T. M., Mukherjee, S., Crane, P. K., Aisen, P. S., Petersen, R. C., Weiner, M. W. & Saykin, A. J., Aug 6 2012, In : Brain Imaging and Behavior. 6, 4, p. 634-648 15 p.

Research output: Contribution to journalArticle

48 Scopus citations

Genomic copy number analysis in Alzheimer's disease and mild cognitive impairment: An ADNI study

Saykin, A. J., Swaminathan, S., Kim, S., Shen, L., Risacher, S. L., Foroud, T., Pankratz, N., Potkin, S. G., Huentelman, M. J., Craig, D. W. & Weiner, M. W., 2011, In : International Journal of Alzheimer's Disease. 729478.

Research output: Contribution to journalArticle

41 Scopus citations

GPU Accelerated Browser for Neuroimaging Genomics

Alzheimer’s Disease Neuroimaging Initiative, Oct 1 2018, In : Neuroinformatics. 16, 3-4, p. 393-402 10 p.

Research output: Contribution to journalArticle

Graphic Mining of High-Order Drug Interactions and Their Directional Effects on Myopathy Using Electronic Medical Records

Du, L., Chakraborty, A., Chiang, C. W., Cheng, L., Quinney, S. K., Wu, H., Zhang, P., Li, L. & Shen, L., Aug 1 2015, In : CPT: Pharmacometrics and Systems Pharmacology. 4, 8, p. 481-488 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

GWAS of longitudinal amyloid accumulation on 18F-florbetapir PET in Alzheimer's disease implicates microglial activation gene IL1RAP

Ramanan, V. K., Risacher, S. L., Nho, K., Kim, S., Shen, L., McDonald, B. C., Yoder, K. K., Hutchins, G. D., West, J. D., Tallman, E. F., Gao, S., Foroud, T. M., Farlow, M. R., De Jager, P. L., Bennett, D. A., Aisen, P. S., Petersen, R. C., Jack, C. R., Toga, A. W., Green, R. C. & 3 others, Jagust, W. J., Weiner, M. W. & Saykin, A. J., Oct 1 2015, In : Brain. 138, 10, p. 3076-3088 13 p.

Research output: Contribution to journalArticle

62 Scopus citations

Hierarchical Structured Sparse Learning for Schizophrenia Identification

Wang, M., Hao, X., Huang, J., Wang, K., Shen, L., Xu, X., Zhang, D. & Liu, M., Jan 1 2020, In : Neuroinformatics. 18, 1, p. 43-57 15 p.

Research output: Contribution to journalArticle