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  • Li Shen
2018

A Review of Statistical-learning Imaging Genetics

Hao, X. K., Li, C. X., Yan, J. W., Shen, L. & Zhang, D. Q., Jan 2018, In : Zidonghua Xuebao/Acta Automatica Sinica. 44, 1, p. 13-24 12 p.

Research output: Contribution to journalReview article

Bootstrapped Sparse Canonical Correlation Analysis: Mining Stable Imaging and Genetic Associations With Implicit Structure Learning. Mining Stable Imaging and Genetic Associations With Implicit Structure Learning.

Yan, J., Du, L., Kim, S., Risacher, S. L., Huang, H., Inlow, M., Moore, J. H., Saykin, A. J. & Shen, L., Jan 1 2018, Imaging Genetics. Elsevier Inc., p. 101-117 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Characteristic patterns of inter- and intra-hemispheric metabolic connectivity in patients with stable and progressive mild cognitive impairment and Alzheimer’s disease

for the Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2018, In : Scientific reports. 8, 1, 13807.

Research output: Contribution to journalArticle

4 Scopus citations

GPU Accelerated Browser for Neuroimaging Genomics

Alzheimer’s Disease Neuroimaging Initiative, Oct 1 2018, In : Neuroinformatics. 16, 3-4, p. 393-402 10 p.

Research output: Contribution to journalArticle

Heritability estimation of reliable connectomic features

Xie, L., Amico, E., Salama, P., Wu, Y. C., Fang, S., Sporns, O., Saykin, A. J., Goñi, J., Yan, J. & Shen, L., Jan 1 2018, Connectomics in NeuroImaging - 2nd International Workshop, CNI 2018, Held in Conjunction with MICCAI 2018, Proceedings. Wu, G., Schirmer, M. D., Chung, A. W., Rekik, I. & Munsell, B. (eds.). Springer Verlag, p. 58-66 9 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11083 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Image Registration and Predictive Modeling: Learning the Metric on the Space of Diffeomorphisms

Mussabayeva, A., Kroshnin, A., Kurmukov, A., Denisova, Y., Shen, L., Cong, S., Wang, L. & Gutman, B. A., Jan 1 2018, Shape in Medical Imaging - International Workshop, ShapeMI 2018, Held in Conjunction with MICCAI 2018, Proceedings. Lombaert, H., Paniagua, B., Egger, B., Lüthi, M., Reuter, M. & Wachinger, C. (eds.). Springer Verlag, p. 160-168 9 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11167 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Imaging genomics

Huang, H., Shen, L., Thompson, P. M., Huang, K., Huang, J. & Yang, L., 2018, In : Pacific Symposium on Biocomputing. 0, 212669, p. 304-306 3 p.

Research output: Contribution to journalConference article

2 Scopus citations

Joint exploration and mining of memory-relevant brain anatomic and connectomic patterns via a three-way association model

Yan, J., Liu, K., Lv, H., Amico, E., Risacher, S. L., Wu, Y. C., Fang, S., Sporns, O., Saykin, A. J., Goni, J. & Shen, L., May 23 2018, 2018 IEEE 15th International Symposium on Biomedical Imaging, ISBI 2018. IEEE Computer Society, p. 6-9 4 p. (Proceedings - International Symposium on Biomedical Imaging; vol. 2018-April).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Joint high-order multi-task feature learning to predict the progression of Alzheimer’s disease

ADNI, Jan 1 2018, Medical Image Computing and Computer Assisted Intervention – MICCAI 2018 - 21st International Conference, 2018, Proceedings. Schnabel, J. A., Davatzikos, C., Alberola-López, C., Fichtinger, G. & Frangi, A. F. (eds.). Springer Verlag, p. 555-562 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11070 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Longitudinal genotype-phenotype association study through temporal structure auto-learning predictive model

Wang, X., Yan, J., Yao, X., Kim, S., Nho, K., Risacher, S. L., Saykin, A. J., Shen, L. & Huang, H., Jul 2018, In : Journal of Computational Biology. 25, 7, p. 809-824 16 p.

Research output: Contribution to journalArticle

2 Scopus citations

Mixture drug-count response model for the high-dimensional drug combinatory effect on myopathy

Wang, X., Zhang, P., Chiang, C. W., Wu, H., Shen, L., Ning, X., Zeng, D., Wang, L., Quinney, S. K., Feng, W. & Li, L., Feb 20 2018, In : Statistics in Medicine. 37, 4, p. 673-686 14 p.

Research output: Contribution to journalArticle

4 Scopus citations

Multiple incomplete views clustering via non-negative matrix factorization with its application in Alzheimer's disease analysis

Liu, K., Wang, H., Risacher, S., Saykin, A. & Shen, L., May 23 2018, 2018 IEEE 15th International Symposium on Biomedical Imaging, ISBI 2018. IEEE Computer Society, Vol. 2018-April. p. 1402-1405 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Pattern Discovery from High-Order Drug-Drug Interaction Relations

Chiang, W. H., Schleyer, T., Shen, L., Li, L. & Ning, X., Sep 1 2018, In : Journal of Healthcare Informatics Research. 2, 3, p. 272-304 33 p.

Research output: Contribution to journalArticle

Predicting progressions of cognitive outcomes via high-order multi-modal multi-task feature learning

Lu, L., Wang, H., Yao, X., Risacher, S., Saykin, A. & Shen, L., May 23 2018, 2018 IEEE 15th International Symposium on Biomedical Imaging, ISBI 2018. IEEE Computer Society, Vol. 2018-April. p. 545-548 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Quantitative trait loci identification for brain endophenotypes via new additive model with random networks

Wang, X., Chen, H., Yan, J., Nho, K., Risacher, S. L., Saykin, A. J., Shen, L. & Huang, H., Sep 1 2018, In : Bioinformatics. 34, 17, p. i866-i874

Research output: Contribution to journalArticle

1 Scopus citations

Translational High-Dimensional Drug Interaction Discovery and Validation Using Health Record Databases and Pharmacokinetics Models

Chiang, C. W., Zhang, P., Wang, X., Wang, L., Zhang, S., Ning, X., Shen, L., Quinney, S. K. & Li, L., Feb 2018, In : Clinical Pharmacology and Therapeutics. 103, 2, p. 287-295 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

The Genetic FTD Initiative (GENFI) & The Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dec 1 2018, In : Nature communications. 9, 1, 4273.

Research output: Contribution to journalArticle

33 Scopus citations

Volumetric comparison of hippocampal subfields extracted from 4-minute accelerated vs. 8-minute high-resolution T2-weighted 3T MRI scans

Cong, S., Risacher, S. L., West, J. D., Wu, Y. C., Apostolova, L. G., Tallman, E., Rizkalla, M., Salama, P., Saykin, A. J. & Shen, L., Dec 1 2018, In : Brain Imaging and Behavior. 12, 6, p. 1583-1595 13 p.

Research output: Contribution to journalArticle

3 Scopus citations
2017

A fast SCCA algorithm for big data analysis in brain imaging genetics

Alzheimer’s Disease Neuroimaging Initiative, 2017, Graphs in Biomedical Image Analysis, Computational Anatomy and Imaging Genetics - 1st International Workshop, GRAIL 2017 6th International Workshop, MFCA 2017 and 3rd International Workshop, MICGen 2017 Held in Conjunction with MICCAI 2017, Proceedings. Springer Verlag, Vol. 10551 LNCS. p. 210-219 10 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10551 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Association analysis of rare variants near the APOE region with CSF and neuroimaging biomarkers of Alzheimer’s disease

Nho, K., Kim, S., Horgusluoglu, E., Risacher, S. L., Shen, L., Kim, D., Lee, S., Foroud, T., Shaw, L. M., Trojanowski, J. Q., Aisen, P. S., Petersen, R. C., Jack, C. R., Weiner, M. W., Green, R. C., Toga, A. W. & Saykin, A. J., May 24 2017, In : BMC Medical Genomics. 10, 29.

Research output: Contribution to journalArticle

9 Scopus citations

Association of plasma neurofilament light with neurodegeneration in patients with Alzheimer disease

Alzheimer's Disease Neuroimaging Initiative, May 2017, In : JAMA Neurology. 74, 5, p. 557-566 10 p.

Research output: Contribution to journalArticle

214 Scopus citations

BECA: A Software Tool for Integrated Visualization of Human Brain Data

Li, H., Fang, S., Zigon, B., Sporns, O., Saykin, A. J., Goñi, J. & Shen, L., Jan 1 2017, Brain Informatics - International Conference, BI 2017, Proceedings. Zeng, Y., Xu, B., Martone, M., He, Y., Peng, H., Luo, Q. & Kotaleski, J. H. (eds.). Springer Verlag, p. 285-291 7 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10654 LNAI).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Brain explorer for connectomic analysis

for the Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2017, In : Brain Informatics. 4, 4, p. 253-269 17 p.

Research output: Contribution to journalArticle

1 Scopus citations

ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide

Thompson, P. M., Dennis, E. L., Gutman, B. A., Hibar, D. P., Jahanshad, N., Kelly, S., Stein, J. L., Whelan, C. D., Andreassen, O. A., Arias-Vasquez, A., Bearden, C. E., Boedhoe, P. S., van den Heuvel, O. L., Veltman, D. J., Brouwer, R. M., de Reus, M. A., Pol, H. E. H., van den Heuvel, M. P., Buckner, R. L., Buitelaar, J. K. & 51 others, Fisher, S. E., Francks, C., Franke, B., Hoogman, M., van Rooij, D., Bulayeva, K. B., Cannon, D. M., McDonald, C., Cohen, R. A., Conrod, P. J., Dale, A. M., Holland, D., Deary, I. J., Wardlaw, J. M., Desrivieres, S., Schumann, G., Dima, D., Frangou, S., Donohoe, G., Guadalupe, T., Fouche, J. P., Stein, D. J., Ganjgahi, H., Garavan, H., Glahn, D. C., Grabe, H. J., Hashimoto, R., Hosten, N., Kochunov, P., Kremen, W. S., Lee, P. H., Mackey, S., Mazoyer, B., Martin, N. G., Medland, S. E., Morey, R. A., Nichols, T. E., Paus, T., Pausova, Z., Shen, L., Sisodiya, S. M., Smit, D. J. A., Smoller, J. W., Toro, R., Turner, J. A., Schmaal, L., van Erp, T. G. M., Walter, H., Wang, Y., Wright, M. J. & Ye, J., Jan 15 2017, In : NeuroImage. 145, p. 389-408 20 p.

Research output: Contribution to journalArticle

84 Scopus citations

Genome-wide association and interaction studies of CSF T-tau/Aβ42 ratio in ADNI cohort

Li, J., Zhang, Q., Chen, F., Meng, X., Liu, W., Chen, D., Yan, J., Kim, S., Wang, L., Feng, W., Saykin, A. J., Liang, H. & Shen, L., Sep 2017, In : Neurobiology of Aging. 57, p. 247.e1-247.e8

Research output: Contribution to journalArticle

12 Scopus citations

Genome-wide network-based pathway analysis of CSF t-tau/Aβ1-42 ratio in the ADNI cohort

for the Alzheimer's Disease Neuroimaging Initiative, May 30 2017, In : BMC genomics. 18, 1, 421.

Research output: Contribution to journalArticle

6 Scopus citations

Identification of associations between genotypes and longitudinal phenotypes via temporally-constrained group sparse canonical correlation analysis

Hao, X., Li, C., Yan, J., Yao, X., Risacher, S. L., Saykin, A. J., Shen, L. & Zhang, D., Jul 15 2017, In : Bioinformatics. 33, 14, p. i341-i349

Research output: Contribution to journalArticle

10 Scopus citations

Identification of discriminative imaging proteomics associations in Alzheimer’s disease via a novel sparse correlation model

Alzheimer's Disease Neuroimaging Initiative, 2017, In : Pacific Symposium on Biocomputing. 0, 212679, p. 94-104 11 p.

Research output: Contribution to journalConference article

Open Access
5 Scopus citations

Identifying associations between brain imaging phenotypes and genetic factors via a novel structured SCCA approach

Du, L., Zhang, T., Liu, K., Yan, J., Yao, X., Risacher, S. L., Saykin, A., Han, J., Guo, L. & Shen, L., 2017, Information Processing in Medical Imaging - 25th International Conference, IPMI 2017, Proceedings. Springer Verlag, Vol. 10265 LNCS. p. 543-555 13 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10265 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations

Imaging genomics

Shen, L. & Cooper, L. A. D., 2017, In : Pacific Symposium on Biocomputing. 0, 212679, p. 51-57 7 p.

Research output: Contribution to journalConference article

2 Scopus citations

Longitudinal genotype-phenotype association study via temporal structure auto-learning predictive model

The ADNI, Jan 1 2017, Research in Computational Molecular Biology - 21st Annual International Conference, RECOMB 2017, Proceedings. Sahinalp, S. C. (ed.). Springer Verlag, p. 287-302 16 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10229 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Mapping longitudinal scientific progress, collaboration and impact of the Alzheimer’s disease neuroimaging initiative

Alzheimer’s Disease Neuroimaging Initiative, Nov 2017, In : PloS one. 12, 11, e0186095.

Research output: Contribution to journalArticle

5 Scopus citations

Metabolic network failures in Alzheimer's disease: A biochemical road map

Alzheimer's Disease Neuroimaging Initiative and the Alzheimer Disease Metabolomics Consortium, Sep 2017, In : Alzheimer's and Dementia. 13, 9, p. 965-984 20 p.

Research output: Contribution to journalArticle

92 Scopus citations

Mining outcome-relevant brain imaging genetic associations via three-way sparse canonical correlation analysis in Alzheimer's disease

Hao, X., Li, C., Du, L., Yao, X., Yan, J., Risacher, S. L., Saykin, A., Shen, L. & Zhang, D., Mar 14 2017, In : Scientific Reports. 7, 44272.

Research output: Contribution to journalArticle

10 Scopus citations

Network approaches to systems biology analysis of complex disease: Integrative methods for multi-omics data

Yan, J., Risacher, S. L., Shen, L. & Saykin, A. J., May 30 2017, In : Briefings in Bioinformatics. 19, 6, p. 1370-1381 12 p.

Research output: Contribution to journalArticle

47 Scopus citations

Network-based genome wide study of hippocampal imaging phenotype in Alzheimer's Disease to identify functional interaction modules

Yao, X., Yan, J., Risacher, S., Moore, J., Saykin, A. & Shen, L., Jun 16 2017, 2017 IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc., p. 6170-6174 5 p. 7953342. (ICASSP, IEEE International Conference on Acoustics, Speech and Signal Processing - Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

New probabilistic multi-graph decomposition model to identify consistent human brain network modules

Luo, D., Huo, Z., Wang, Y., Saykin, A. J., Shen, L. & Huang, H., Jan 31 2017, Proceedings - 16th IEEE International Conference on Data Mining, ICDM 2016. Bonchi, F., Wu, X., Baeza-Yates, R., Domingo-Ferrer, J. & Zhou, Z-H. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 301-310 10 p. 7837854. (Proceedings - IEEE International Conference on Data Mining, ICDM).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Novel genetic loci associated with hippocampal volume

Hibar, D. P., Adams, H. H. H., Jahanshad, N., Chauhan, G., Stein, J. L., Hofer, E., Renteria, M. E., Bis, J. C., Arias-Vasquez, A., Ikram, M. K., Desrivières, S., Vernooij, M. W., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S., Armstrong, N. J., Athanasiu, L. & 312 others, Axelsson, T., Beecham, A. H., Beiser, A., Bernard, M., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chen, Q., Ching, C. R. K., Chouraki, V., Cuellar-Partida, G., Crivello, F., Den Braber, A., Doan, N. T., Ehrlich, S., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Grimm, O., Griswold, M. E., Guadalupe, T., Gutman, B. A., Hass, J., Haukvik, U. K., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Jørgensen, K. N., Karbalai, N., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liewald, D. C. M., Lopez, L. M., Luciano, M., MacAre, C., Marquand, A. F., Matarin, M., Mather, K. A., Mattheisen, M., McKay, D. R., Milaneschi, Y., Muñoz Maniega, S., Nho, K., Nugent, A. C., Nyquist, P., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pirpamer, L., Pütz, B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-Santiañez, R., Rommelse, N., Ropele, S., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Saremi, A., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Tordesillas-Gutierrez, D., Toro, R., Trabzuni, D., Trompet, S., Vaidya, D., Van Der Grond, J., Van Der Lee, S. J., Van Der Meer, D., Van Donkelaar, M. M. J., Van Eijk, K. R., Van Erp, T. G. M., Van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Wittfeld, K., Woldehawariat, G., Wolf, C., Wolfers, T., Yanek, L. R., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., Van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Cheng, C. Y., Cichon, S., Cookson, M. R., Corvin, A., Crespo-Facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., De Craen, A. J. M., De Geus, E. J. C., De Jager, P. L., De Zubicaray, G. I., Deary, I. J., Debette, S., Decarli, C., Delanty, N., Depondt, C., Destefano, A., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Enzinger, C., Erk, S., Espeseth, T., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Fornage, M., Foroud, T. M., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Håberg, A. K., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B. C., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J. J., Huentelman, M., Pol, H. E. H., Ikeda, M., Jack, C. R., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J. L., Mattay, V. S., McDonald, C., McIntosh, A. M., McMahon, F. J., McMahon, K. L., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Potkin, S. G., Psaty, B. M., Reppermund, S., Rietschel, M., Roffman, J. L., Romanczuk-Seiferth, N., Rotter, J. I., Ryten, M., Sacco, R. L., Sachdev, P. S., Saykin, A., Schmidt, R., Schmidt, H., Schofield, P. R., Sigursson, S., Simmons, A., Singleton, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soininen, H., Steen, V. M., Stott, D. J., Sussmann, J. E., Thalamuthu, A., Toga, A. W., Traynor, B. J., Troncoso, J., Tsolaki, M., Tzourio, C., Uitterlinden, A. G., Hernández, M. C. V., Van Der Brug, M., Van Der Lugt, A., Van Der Wee, N. J. A., Van Haren, N. E. M., Van 'T Ent, D., Van Tol, M. J., Vardarajan, B. N., Vellas, B., Veltman, D. J., Völzke, H., Walter, H., Wardlaw, J. M., Wassink, T. H., Weale, M. E., Weinberger, D. R., Weiner, M. W., Wen, W., Westman, E., White, T., Wong, T. Y., Wright, C. B., Zielke, R. H., Zonderman, A. B., Martin, N. G., Van Duijn, C. M., Wright, M. J., Longstreth, W. T., Schumann, G., Grabe, H. J., Franke, B., Launer, L. J., Medland, S. E., Seshadri, S., Thompson, P. M. & Ikram, M. A., Jan 18 2017, In : Nature communications. 8, 13624.

Research output: Contribution to journalArticle

97 Scopus citations

Parcellation of human amygdala subfields using orientation distribution function and spectral k-means clustering

Wen, Q., Stirling, B. D., Sha, L., Shen, L., Whalen, P. J. & Wu, Y. C., 2017, Computational Diffusion MRI - MICCAI Workshop. Fuster, A., Rathi, Y., Reisert, M., Kaden, E. & Ghosh, A. (eds.). Springer Heidelberg, p. 123-132 10 p. (Mathematics and Visualization).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Pattern Discovery from Directional High-Order Drug-Drug Interaction Relations

Ning, X., Schleyer, T., Shen, L. & Li, L., Sep 8 2017, Proceedings - 2017 IEEE International Conference on Healthcare Informatics, ICHI 2017. Cummins, M., Facelli, J., Meixner, G., Giraud-Carrier, C. & Nakajima, H. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 154-162 9 p. 8031143. (Proceedings - 2017 IEEE International Conference on Healthcare Informatics, ICHI 2017).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty

Du, L., Liu, K., Yao, X., Yan, J., Risacher, S. L., Han, J., Guo, L., Saykin, A. J., Shen, L., Weiner, M. W., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Morris, J., Shaw, L. M. & 293 others, Khachaturian, Z., Sorensen, G., Carrillo, M., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M. M., Potter, W., Snyder, P., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Balasubramanian, A. B., Mason, J., Sim, I., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., Decarli, C., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Landau, S., Cairns, N. J., Franklin, E., Taylor-Reinwald, L., Lee, V., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T. M., Potkin, S., Faber, K., Kim, S., Nho, K., Thal, L., Buckholtz, N., Albert, M., Frank, R., Hsiao, J., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Pavlik, V., Shibley, V., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Creech, M. L., Franklin, E., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Geldmacher, D., Love, M. N., Griffith, R., Clark, D., Brockington, J., Roberson, E., Grossman, H., Mitsis, E., Shah, R. C., Detoledo-Morrell, L., Duara, R., Greig-Custo, M. T., Barker, W., Onyike, C., D'Agostino, D., Kielb, S., Sadowski, M., Sheikh, M. O., Ulysse, A., Gaikwad, M., Murali Doraiswamy, P., Petrella, J. R., Borges-Neto, S., Wong, T. Z., Coleman, E., Arnold, S. E., Karlawish, J. H., Wolk, D. A., Clark, C. M., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Lopez, O. L., Oakley, M. A., Simpson, D. M., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Ismail, M. S., Brand, C., Preda, A., Nguyen, D., Womack, K., Mathews, D., Quiceno, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Swerdlow, R. H., Brooks, W. M., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Poki-Walker, K., Farlow, M. R., Marie Hake, A., Matthews, B., Brosch, J. R., Herring, S., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Mudge, B., Sossi, V., Feldman, H., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Rogers, J., Trost, D., Kertesz, A., Bernick, C., Munic, D., Rogalski, E., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Scott Turner, R., Johnson, K., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Lynn Johnson, P., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Tariot, P., Burke, A., Milliken, A. M., Trncic, N., Fleisher, A., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Kelly, B., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Flashman, L. A., Seltzer, M., Hynes, M. L., Santulli, R. B., Sink, K. M., Gordineer, L., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Tremont, G., Daiello, L. A., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S. K., Ekstam Smith, K., Koleva, H., Nam, K. W., Shim, H., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Ashok Raj, B. & Fargher, K., Dec 1 2017, In : Scientific reports. 7, 1, 14052.

Research output: Contribution to journalArticle

4 Scopus citations

Predicting High-Order Directional Drug-Drug Interaction Relations

Ning, X., Shen, L. & Li, L., Sep 8 2017, Proceedings - 2017 IEEE International Conference on Healthcare Informatics, ICHI 2017. Cummins, M., Facelli, J., Meixner, G., Giraud-Carrier, C. & Nakajima, H. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 556-561 6 p. 8031212. (Proceedings - 2017 IEEE International Conference on Healthcare Informatics, ICHI 2017).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Predicting interrelated Alzheimer’s disease outcomes via new self-learned structured low-rank model

Wang, X., Liu, K., Yan, J., Risacher, S. L., Saykin, A. J., Shen, L. & Huang, H., Jan 1 2017, Information Processing in Medical Imaging - 25th International Conference, IPMI 2017, Proceedings. Zhu, H., Niethammer, M., Styner, M., Zhu, H., Shen, D., Yap, P-T., Aylward, S. & Oguz, I. (eds.). Springer Verlag, p. 198-209 12 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10265 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Preface micgen 2017

Dalca, A. V., Batmanghelich, N. K., Sabuncu, M. R. & Shen, L., Jan 1 2017, In : Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 10551 LNCS

Research output: Contribution to journalEditorial

Sparse Canonical Correlation Analysis via truncated ℓ1-norm with application to brain imaging genetics

Du, L., Zhang, T., Liu, K., Yao, X., Yan, J., Risacher, S. L., Guo, L., Saykin, A. J. & Shen, L., Jan 17 2017, Proceedings - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016. Burrage, K., Zhu, Q., Liu, Y., Tian, T., Wang, Y., Hu, X. T., Jiang, Q., Song, J., Morishita, S., Burrage, K. & Wang, G. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 707-711 5 p. 7822605. (Proceedings - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Statistical Shape Analysis for Brain Structures

Shen, L., Cong, S. & Inlow, M., Mar 23 2017, Statistical Shape and Deformation Analysis: Methods, Implementation and Applications. Elsevier Inc., p. 351-378 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Tissue-specific network-based genome wide study of amygdala imaging phenotypes to identify functional interaction modules

Alzheimer's Disease Neuroimaging Initiative, Oct 15 2017, In : Bioinformatics. 33, 20, p. 3250-3257 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Transcriptome-guided imaging genetic analysis via a novel sparse CCA algorithm

Alzheimer’s Disease Neuroimaging Initiative, 2017, Graphs in Biomedical Image Analysis, Computational Anatomy and Imaging Genetics - 1st International Workshop, GRAIL 2017 6th International Workshop, MFCA 2017 and 3rd International Workshop, MICGen 2017 Held in Conjunction with MICCAI 2017, Proceedings. Springer Verlag, Vol. 10551 LNCS. p. 220-229 10 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10551 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Two-dimensional enrichment analysis for mining high-level imaging genetic associations

Yao, X., Yan, J., Kim, S., Nho, K., Risacher, S. L., Inlow, M., Moore, J. H., Saykin, A. J. & Shen, L., Mar 1 2017, In : Brain Informatics. 4, 1, p. 27-37 11 p.

Research output: Contribution to journalArticle

5 Scopus citations
2016

A new statistical image analysis approach and its application to Hippocampal morphometry

ADNI, 2016, Medical Imaging and Augmented Reality - 7th International Conference, MIAR 2016, Proceedings. Liao, H., Zheng, G., Lee, S-L., Cattin, P. & Jannin, P. (eds.). Springer Verlag, p. 302-310 9 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 9805 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations