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  • Liang Cheng

Renal Cell Carcinoma with Chromosome 6p Amplification Including the TFEB Gene: A Novel Mechanism of Tumor Pathogenesis?

Williamson, S. R., Grignon, D. J., Cheng, L., Favazza, L., Gondim, D. D., Carskadon, S., Gupta, N. S., Chitale, D. A., Kalyana-Sundaram, S. & Palanisamy, N., Jan 1 2017, In : American Journal of Surgical Pathology. 41, 3, p. 287-298 12 p.

Research output: Contribution to journalArticle

26 Scopus citations
2 Scopus citations

Rhabdoid and undifferentiated phenotype in renal cell carcinoma: Analysis of 32 cases indicating a distinctive common pathway of dedifferentiation frequently associated with SWI/SNF complex deficiency

Agaimy, A., Cheng, L., Egevad, L., Feyerabend, B., Hes, O., Keck, B., Pizzolitto, S., Sioletic, S., Wullich, B. & Hartmann, A., Jan 1 2017, In : American Journal of Surgical Pathology. 41, 2, p. 253-262 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Solitary fibrous tumour of the genitourinary tract: A clinicopathological study of 11 cases and their association with the NAB2-STAT6 fusion gene

Kouba, E., Simper, N. B., Chen, S., Williamson, S. R., Grignon, D. J., Eble, J. N., MacLennan, G. T., Montironi, R., Lopez-Beltran, A., Osunkoya, A. O., Zhang, S., Wang, M., Wang, L., Tran, T., Emerson, R. E., Baldrige, L. A., Monn, M. F., Linos, K. & Cheng, L., Jun 1 2017, In : Journal of clinical pathology. 70, 6, p. 508-514 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Targeting the programmed cell death-1 pathway in genitourinary tumors: Current progress and future perspectives

Mann, S. A., Lopez-Beltran, A., Massari, F., Pili, R., Fiorentino, M., Koch, M. O., Kaimakliotis, H. Z., Wang, L., Scarpelli, M., Ciccarese, C., Moch, H., Montironi, R. & Cheng, L., Jan 1 2017, In : Current drug metabolism. 18, 8, p. 700-711 12 p.

Research output: Contribution to journalReview article

17 Scopus citations

TERT Promoter Mutations Occur Frequently in Urothelial Papilloma and Papillary Urothelial Neoplasm of Low Malignant Potential

Cheng, L., Montironi, R. & Lopez-Beltran, A., Mar 1 2017, In : European Urology. 71, 3, p. 497-498 2 p.

Research output: Contribution to journalLetter

13 Scopus citations

TERT promoter mutation status in sarcomatoid urothelial carcinomas of the upper urinary tract

Wang, X., Lopez-Beltran, A., Osunkoya, A. O., Wang, M., Zhang, S., Davidson, D., Emerson, R., Williamson, S. R., Tan, P. H., Kaimakliotis, H., Baldridge, L. A., MacLennan, G. T., Montironi, R. & Cheng, L., Apr 1 2017, In : Future Oncology. 13, 8, p. 705-714 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Testicular cancer: The usage of central review for pathology diagnosis of orchiectomy specimens

Harari, S. E., Sassoon, D. J., Priemer, D. S., Jacob, J. M., Eble, J. N., Caliò, A., Grignon, D. J., Idrees, M., Albany, C., Masterson, T. A., Hanna, N. H., Foster, R. S., Ulbright, T. M., Einhorn, L. H. & Cheng, L., Oct 2017, In : Urologic Oncology: Seminars and Original Investigations. 35, 10, p. 605.e9-605.e16

Research output: Contribution to journalArticle

6 Scopus citations

TMPRSS2-ERG Fusion in an Uncommon Presentation of Prostate Cancer

Adra, N., Cheng, L., Hanna, N. H. & Durm, G., Jun 2017, In : Clinical Genitourinary Cancer. 15, 3, p. e489-e491

Research output: Contribution to journalArticle

TMPRSS2-ERG gene fusion is rare compared to PTEN deletions in stage T1a prostate cancer

Fisher, K. W., Zhang, S., Wang, M., Montironi, R., Wang, L., Baldrige, L. A., Wang, J. Y., MacLennan, G. T., Williamson, S. R., Lopez-Beltran, A. & Cheng, L., Mar 1 2017, In : Molecular Carcinogenesis. 56, 3, p. 814-820 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Tp53 and its potential therapeutic role as a target in bladder cancer

Ciccarese, C., Massari, F., Blanca, A., Tortora, G., Montironi, R., Cheng, L., Scarpelli, M., Raspollini, M. R., Vau, N., Fonseca, J. & Lopez-Beltran, A., Apr 3 2017, In : Expert Opinion on Therapeutic Targets. 21, 4, p. 401-414 14 p.

Research output: Contribution to journalReview article

9 Scopus citations

Unclassified Renal Cell Carcinoma With Significant Response to Nivolumab

Adra, N., Cheng, L. & Pili, R., Jun 2017, In : Clinical Genitourinary Cancer. 15, 3, p. e517-e519

Research output: Contribution to journalArticle

4 Scopus citations

Understanding the Genetic Landscape of Small Cell Carcinoma of the Urinary Bladder and Implications for Diagnosis, Prognosis, and Treatment: A Review

Kouba, E. J. & Cheng, L., Nov 1 2017, In : JAMA oncology. 3, 11, p. 1570-1578 9 p.

Research output: Contribution to journalReview article

12 Scopus citations

Urinary biomarkers for prostate cancer

Giunchi, F., Ciccarese, C., Montironi, R., Scarpelli, M., Lopez-Beltran, A., Cheng, L., Moch, H., Massari, F. & Fiorentino, M., Jan 1 2017, In : Current Drug Metabolism. 18, 8, p. 723-726 4 p.

Research output: Contribution to journalReview article

5 Scopus citations

Use of Precision Medicine Molecular Profiling of Baseline Tumor Specimen May Not Benefit Outcomes in Children With Relapsed or Refractory Pediatric Sarcomas

Carter, J., Cheng, L., Zucker, J., Marshall, M., Pollok, K., Murray, M., Li, L. & Renbarger, J., Mar 1 2017, In : Clinical Pharmacology and Therapeutics. 101, 3, p. 328-330 3 p.

Research output: Contribution to journalArticle

Validation of 34betaE12 immunoexpression in clear cell papillary renal cell carcinoma as a sensitive biomarker

Martignoni, G., Brunelli, M., Segala, D., Munari, E., Gobbo, S., Cima, L., Borze, I., Wirtanen, T., Sarhadi, V. K., Atanesyan, L., Savola, S., Barzon, L., Masi, G., Fassan, M., Eble, J., Bohling, T., Cheng, L., Delahunt, B. & Knuutila, S., Jan 1 2017, In : Pathology. 49, 1, p. 10-18 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Variants and Variations in Epithelial Renal Cell Tumors in Adults: The Pathologist's Point of View

Montironi, R., Gasparrini, S., Cimadamore, A., Mazzucchelli, R., Massari, F., Cheng, L., Lopez-Beltran, A., Moch, H., Montorsi, F. & Scarpelli, M., Dec 2017, In : European Urology, Supplements. 16, 12, p. 232-240 9 p.

Research output: Contribution to journalReview article

1 Scopus citations

Variants of Bladder Cancer: The Pathologist's Point of View[figure parsented]

Lopez-Beltran, A., Cheng, L., Raspollini, M. R., Canas-Marques, R., Scarpelli, M., Cimadamore, A., Gasparrini, S. & Montironi, R., Dec 1 2017, In : European Urology, Supplements. 16, 12, p. 210-222 13 p.

Research output: Contribution to journalReview article

9 Scopus citations

Whole slide imaging of large format histology in prostate pathology: Potential for information fusion

Montironi, R., Cimadamore, A., Massari, F., Montironi, M. A., Lopez-Beltran, A., Cheng, L., Montorsi, F. & Scarpelli, M., Nov 1 2017, In : Archives of Pathology and Laboratory Medicine. 141, 11, p. 1460-1461 2 p.

Research output: Contribution to journalLetter

3 Scopus citations
2016

2016 World Health Organization classification of tumors of the kidney: An update

Rao, Q., Xia, Q., Zhou, X. & Cheng, L., Jul 1 2016, In : Chinese Journal of Pathology. 45, 7, p. 435-441 7 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

2016 World Health Organization classification of tumors of the urinary tract: An update

Huang, W. & Cheng, L., Jul 1 2016, In : Chinese Journal of Pathology. 45, 7, p. 441-445 5 p.

Research output: Contribution to journalComment/debate

Ambient ionization mass spectrometric analysis of human surgical specimens to distinguish renal cell carcinoma from healthy renal tissue

Alfaro, C. M., Jarmusch, A. K., Pirro, V., Kerian, K. S., Masterson, T. A., Cheng, L. & Cooks, R. G., Aug 1 2016, In : Analytical and Bioanalytical Chemistry. 408, 20, p. 5407-5414 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

An overview of emerging immunotargets of genitourinary tumors

Montironi, R., Santoni, M., Cheng, L., Lopez-Beltran, A., Massari, F., Matrana, M. R., Moch, H. & Scarpelli, M., Jun 1 2016, In : Current Drug Targets. 17, 7, p. 750-756 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Atypical renal cysts a morphologic, immunohistochemical, and molecular study

Matoso, A., Chen, Y. B., Rao, V., Wang, L., Cheng, L. & Epstein, J. I., Jan 1 2016, In : American Journal of Surgical Pathology. 40, 2, p. 202-211 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Bone homing and metastasis

Santoni, M., Lopez-Beltran, A., Scarpelli, M., Mazzucchelli, R., Berardi, R., Cheng, L. & Montironi, R., Jan 1 2016, Bone Metastases from Prostate Cancer: Biology, Diagnosis and Management. Springer International Publishing, p. 25-32 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Cholesterol sulfonation enzyme, SULT2B1b, modulates AR and cell growth properties in prostate cancer

Vickman, R. E., Crist, S. A., Kerian, K., Eberlin, L., Graham Cooks, R., Burcham, G. N., Buhman, K. K., Hu, C. D., Mesecar, A. D., Cheng, L. & Ratliff, T. L., Sep 1 2016, In : Molecular Cancer Research. 14, 9, p. 776-786 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Chromosome 12p abnormalities and IMP3 expression in prepubertal pure testicular teratomas

Cornejo, K. M., Cheng, L., Church, A., Wang, M. & Jiang, Z., Mar 1 2016, In : Human pathology. 49, p. 54-60 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Clinical benefit of a precision medicine based approach for guiding treatment of refractory cancers

Radovich, M., Kiel, P. J., Nance, S. M., Niland, E. E., Parsley, M. E., Ferguson, M. E., Jiang, G., Ammakkanavar, N. R., Einhorn, L. H., Cheng, L., Nassiri, M., Davidson, D. D., Rushing, D. A., Loehrer, P. J., Pili, R., Hanna, N., Thomas Callaghan, J., Skaar, T. C., Helft, P. R., Shahda, S. & 2 others, O'Neil, B. H. & Schneider, B. P., 2016, In : Oncotarget. 7, 35, p. 56491-56500 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Clinical impact of tumoral angiogenesis on renal cell carcinoma management: where do we stand?

Bianconi, M., Faloppi, L., Lopez-Beltran, A., Scarpelli, M., Scartozzi, M., Cheng, L. & Montironi, R., May 3 2016, In : Expert Review of Precision Medicine and Drug Development. 1, 3, p. 229-231 3 p.

Research output: Contribution to journalEditorial

2 Scopus citations

Current Histopathologic and Molecular Characterisations of Prostate Cancer: Towards Individualised Prognosis and Therapies

Santoni, M., Scarpelli, M., Mazzucchelli, R., Lopez-Beltran, A., Cheng, L., Epstein, J. I., Cascinu, S., Briganti, A., Catto, J. W., Montorsi, F. & Montironi, R., Feb 1 2016, In : European urology. 69, 2, p. 186-190 5 p.

Research output: Contribution to journalEditorial

8 Scopus citations

Cysts and epithelial proliferations of the testicular collecting system

Lopez-Beltran, A., Canas-Marques, R., Raspollini, M. R., Montironi, R., Scarpelli, M. & Cheng, L., May 2 2016, Pathology of Testicular and Penile Neoplasms. Springer International Publishing, p. 171-189 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Different prognostic roles of tumor suppressor gene BAP1 in cancer: A systematic review with meta-analysis

Luchini, C., Veronese, N., Yachida, S., Cheng, L., Nottegar, A., Stubbs, B., Solmi, M., Capelli, P., Pea, A., Barbareschi, M., Fassan, M., Wood, L. D. & Scarpa, A., Oct 1 2016, In : Genes Chromosomes and Cancer. 55, 10, p. 741-749 9 p.

Research output: Contribution to journalReview article

34 Scopus citations

Early detection of prostate cancer: Can we have our cake and eat it too?

Masterson, T., Cary, K. C. & Cheng, L., Mar 3 2016, In : Expert Review of Anticancer Therapy. 16, 3, p. 247-249 3 p.

Research output: Contribution to journalArticle

Emerging immunotargets and immunotherapies in prostate cancer

Montironi, R., Santoni, M., Sotte, V., Cheng, L., Lopez-Beltran, A., Massari, F., Matrana, M. R., Moch, H., Berardi, R. & Scarpelli, M., Jun 1 2016, In : Current Drug Targets. 17, 7, p. 777-782 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Emerging immunotargets in bladder cancer

Massari, F., Ciccarese, C., Vau, N., Santoni, M., Montironi, R., Cheng, L., Marques, R. C., Scarpelli, M., Fonseca, J., Matrana, M. R., Holger, M., Cascinu, S., Tortora, G. & Lopez-Beltran, A., Jun 1 2016, In : Current Drug Targets. 17, 7, p. 757-770 14 p.

Research output: Contribution to journalArticle

10 Scopus citations

Emerging immunotargets in genitourinary tumors

Montironi, R., Santoni, M., Massari, F., Lopez-Beltran, A., Cheng, L., Berardi, R. & Scarpelli, M., Jun 1 2016, In : Current Drug Targets. 17, 7, p. 748-749 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

Emerging immunotargets in metastatic renal cell carcinoma

Kucharczyk, J., Matrana, M. R., Santoni, M., Massari, F., Scarpelli, M., Cheng, L., Lopez-Beltran, A., Cascinu, S., Montironi, R. & Holger, M., Jun 1 2016, In : Current Drug Targets. 17, 7, p. 771-776 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

Emerging molecular pathways and targets in neuroendocrine prostate cancer

Monn, M. F., Montironi, R., Lopez-Beltran, A. & Cheng, L., 2016, In : Translational Cancer Research. 5, p. S282-S285

Research output: Contribution to journalComment/debate

Emerging trends in the evaluation and management of small cell prostate cancer: a clinical and molecular perspective

Monn, M. F. & Cheng, L., Oct 2 2016, In : Expert Review of Anticancer Therapy. 16, 10, p. 1029-1037 9 p.

Research output: Contribution to journalReview article

7 Scopus citations

Epithelial to Mesenchymal Transition in Renal Cell Carcinoma: Implications for Cancer Therapy

Piva, F., Giulietti, M., Santoni, M., Occhipinti, G., Scarpelli, M., Lopez-Beltran, A., Cheng, L., Principato, G. & Montironi, R., Mar 3 2016, (Accepted/In press) In : Molecular Diagnosis and Therapy. p. 1-7 7 p.

Research output: Contribution to journalArticle

36 Scopus citations

Essentials of anatomic pathology: Fourth edition

Cheng, L. & Bostwick, D. G., Feb 13 2016, Springer International Publishing. 2109 p.

Research output: Book/ReportBook

2 Scopus citations

Evolving concepts of micropapillary variant urothelial carcinoma

Francesca Monn, M. & Cheng, L., Jan 1 2016, In : Translational Cancer Research. 5, p. S1539-S1542

Research output: Contribution to journalArticle

Evolving terminology and classification of urologic tumors and precursor lesions: An update based on the 2016 WHO classification

Huang, W., Chen, J., Teng, X. & Cheng, L., Jul 1 2016, In : Chinese Journal of Pathology. 45, 7, p. 433-434 2 p.

Research output: Contribution to journalComment/debate

Extranodal extension of lymph node metastasis is a marker of poor prognosis in oesophageal cancer: A systematic review with meta-analysis

Luchini, C., Wood, L. D., Cheng, L., Nottegar, A., Stubbs, B., Solmi, M., Capelli, P., Pea, A., Sergi, G., Manzato, E., Fassan, M., Bagante, F., Bollschweiler, E., Giacopuzzi, S., Kaneko, T., de Manzoni, G., Barbareschi, M., Scarpa, A. & Veronese, N., Jul 7 2016, (Accepted/In press) In : Journal of Clinical Pathology.

Research output: Contribution to journalArticle

13 Scopus citations

Extranodal Extension of Nodal Metastases Is a Poor Prognostic Indicator in Gastric Cancer: a Systematic Review and Meta-analysis

Veronese, N., Fassan, M., Wood, L. D., Stubbs, B., Solmi, M., Capelli, P., Pea, A., Nottegar, A., Sergi, G., Manzato, E., Carraro, S., Maruzzo, M., Cataldo, I., Bagante, F., Barbareschi, M., Cheng, L., Bencivenga, M., de Manzoni, G. & Luchini, C., Jul 13 2016, (Accepted/In press) In : Journal of Gastrointestinal Surgery. p. 1-7 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

FGFR3 and Cyclin D3 as urine biomarkers of bladder cancer recurrence

Blanca, A., Requena, M. J., Alvarez, J., Cheng, L., Montironi, R., Raspollini, M. R., Reymundo, C. & Lopez-Beltran, A., Mar 1 2016, In : Biomarkers in Medicine. 10, 3, p. 243-253 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Genetic mutations in accordance with a low malignant potential tumour are not demonstrated in clear cell papillary renal cell carcinoma

Raspollini, M. R., Castiglione, F., Cheng, L., Montironi, R. & Lopez-Beltran, A., Jun 2016, In : Journal of clinical pathology. 69, 6, p. 547-550 4 p.

Research output: Contribution to journalArticle

8 Scopus citations

Genitourinary cancers: molecular determinants for personalized therapies

Mazzucchelli, R., Gasparrini, S., Galosi, A. B., Massari, F., Raspollini, M. R., Scarpelli, M., Lopez-Beltran, A., Cheng, L. & Montironi, R., Sep 26 2016, In : Urologia. 83, 3, p. 107-109 3 p.

Research output: Contribution to journalEditorial

1 Scopus citations