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  • Lawrence Einhorn
2020

High-dose chemotherapy plus peripheral blood stem cell transplantation for patients with relapsed germ cell tumors and active brain metastases

Kalra, M., Adra, N., Hanna, N., Abonour, R. & Einhorn, L. H., Mar 15 2020, In : Cancer. 126, 6, p. 1202-1207 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Management of residual disease after chemotherapy in germ cell tumors

King, J., Adra, N. & Einhorn, L. H., May 1 2020, In : Current opinion in oncology. 32, 3, p. 250-255 6 p.

Research output: Contribution to journalArticle

Prognostic value of teratoma in primary tumor and postchemotherapy retroperitoneal lymph node dissection specimens in patients with metastatic germ cell tumor

Taza, F., Chovanec, M., Snavely, A., Hanna, N. H., Cary, C., Masterson, T. A., Foster, R. S., Einhorn, L. H., Albany, C. & Adra, N., Apr 20 2020, In : Journal of Clinical Oncology. 38, 12, p. 1338-1345 8 p.

Research output: Contribution to journalArticle

Risk Factors for Acute Kidney Injury During High-dose Chemotherapy and Outcomes for Patients With Relapsed Germ Cell Tumors

Zhang, K. J., Hanna, N. H., Althouse, S. K., Zaid, M. A., Abonour, R., Albany, C., Einhorn, L. H. & Adra, N., Jan 1 2020, (Accepted/In press) In : Clinical Genitourinary Cancer.

Research output: Contribution to journalComment/debate

2019
Open Access
2 Scopus citations
7 Scopus citations

A phase 2, open-label study of brentuximab vedotin in patients with CD30-expressing solid tumors

Sharman, J. P., Wheler, J. J., Einhorn, L., Dowlati, A., Shapiro, G. I., Hilton, J., Burke, J. M., Siddiqi, T., Whiting, N. & Jalal, S. I., Aug 15 2019, In : Investigational New Drugs. 37, 4, p. 738-747 10 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Clinical and genome-wide analysis of cisplatininduced tinnitus implicates novel ototoxic mechanisms

El Charif, O., Mapes, B., Trendowski, M. R., Wheeler, H. E., Wing, C., Dinh, P. C., Frisina, R. D., Feldman, D. R., Hamilton, R. J., Vaughn, D. J., Fung, C., Kollmannsberger, C., Mushiroda, T., Kubo, M., Gamazon, E. R., Cox, N. J., Huddart, R., Ardeshir-Rouhani-Fard, S., Monahan, P., Fossa, S. D. & 3 others, Einhorn, L. H., Travis, L. B. & Dolan, M. E., Jan 1 2019, In : Clinical Cancer Research. 25, 13, p. 4104-4116 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

Clinical and genome-wide analysis of serum platinum levels after cisplatin-based chemotherapy

Trendowski, M. R., El-Charif, O., Ratain, M. J., Monahan, P., Mu, Z., Wheeler, H. E., Dinh, P. C., Feldman, D. R., Ardeshir-Rouhani-Fard, S., Hamilton, R. J., Vaughn, D. J., Fung, C., Kollmannsberger, C., Mushiroda, T., Kubo, M., Hannigan, R., Strathmann, F., Einhorn, L. H., Fossa, S. D., Travis, L. B. & 1 others, Eileen Dolan, M., Oct 1 2019, In : Clinical Cancer Research. 25, 19, p. 5913-5924 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Oncologic Outcomes Following Surgical Management of Clinical Stage II Sex Cord Stromal Tumors

Calaway, A. C., Tachibana, I., Masterson, T. A., Foster, R. S., Einhorn, L. H. & Cary, C., May 2019, In : Urology. 127, p. 74-79 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Safety, Efficacy, and Patient-Reported Health-Related Quality of Life and Symptom Burden with Nivolumab in Patients with Advanced Non–Small Cell Lung Cancer, Including Patients Aged 70 Years or Older or with Poor Performance Status (CheckMate 153)

Spigel, D. R., McCleod, M., Jotte, R. M., Einhorn, L., Horn, L., Waterhouse, D. M., Creelan, B., Babu, S., Leighl, N. B., Chandler, J. C., Couture, F., Keogh, G., Goss, G., Daniel, D. B., Garon, E. B., Schwartzberg, L. S., Sen, R., Korytowsky, B., Li, A., Aanur, N. & 1 others, Hussein, M. A., Sep 2019, In : Journal of Thoracic Oncology. 14, 9, p. 1628-1639 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

The effects of hypogonadism on quality of life in survivors of germ cell tumors treated with surgery alone versus surgery plus platinum-based chemotherapy

Khanal, N., Ahmed, S. S., Kalra, M., Miller, T. J., Brames, M. J., Stump, T. E., Monahan, P., Hanna, N. H. & Einhorn, L. H., Jan 1 2019, (Accepted/In press) In : Supportive Care in Cancer.

Research output: Contribution to journalArticle

2018

Clinical and genetic risk factors for adverse metabolic outcomes in north American testicular cancer survivors

Zaid, M. A., Gathirua-Mwangi, W. G., Fung, C., Monahan, P. O., El-Charif, O., Williams, A. M., Feldman, D. R., Hamilton, R. J., Vaughn, D. J., Beard, C. J., Cook, R., Althouse, S. K., Ardeshir-Rouhani-Fard, S., Dinh, P. C., Sesso, H. D., Einhorn, L. H., Fossa, S. D. & Travis, L. B., Mar 1 2018, In : JNCCN Journal of the National Comprehensive Cancer Network. 16, 3, p. 257-265 9 p.

Research output: Contribution to journalArticle

4 Scopus citations
1 Scopus citations

Cumulative burden of morbidity among testicular cancer survivors after standard cisplatin-based chemotherapy: A multi-institutional study

the Platinum Study Group, May 20 2018, In : Journal of Clinical Oncology. 36, 15, p. 1505-1512 8 p.

Research output: Contribution to journalArticle

19 Scopus citations
6 Scopus citations

Multidisciplinary clinic approach improves overall survival outcomes of patients with metastatic germ-cell tumors

Albany, C., Adra, N., Snavely, A. C., Cary, C., Masterson, T. A., Foster, R. S., Kesler, K., Ulbright, T. M., Cheng, L., Chovanec, M., Taza, F., Ku, K., Brames, M. J., Hanna, N. H. & Einhorn, L. H., Feb 1 2018, In : Annals of Oncology. 29, 2, p. 341-346 6 p.

Research output: Contribution to journalArticle

30 Scopus citations

Phase II trial of pembrolizumab in patients with platinum refractory germ-cell tumors: A Hoosier Cancer Research Network Study GU14-206

Adra, N., Einhorn, L. H., Althouse, S. K., Ammakkanavar, N. R., Musapatika, D., Albany, C., Vaughn, D. & Hanna, N. H., Jan 1 2018, In : Annals of Oncology. 29, 1, p. 209-214 6 p.

Research output: Contribution to journalArticle

47 Scopus citations
6 Scopus citations

Reply to the letter to the editor 'A centralised multidisciplinary clinic approach for germ cell tumours' by Crawford

Albany, C., Adra, N., Snavely, A., Cary, C., Masterson, T., Foster, R., Kesler, K., Ulbright, T., Cheng, L., Chovanec, M., Taza, F., Hanna, N. & Einhorn, L., Jan 1 2018, In : Annals of Oncology. 29, 11, p. 2264-2265 2 p.

Research output: Contribution to journalLetter

4 Scopus citations

Treatment of CD30-Expressing Germ Cell Tumors and Sex Cord Stromal Tumors with Brentuximab Vedotin: Identification and Report of Seven Cases

Albany, C., Einhorn, L., Garbo, L., Boyd, T., Josephson, N. & Feldman, D. R., Mar 2018, In : Oncologist. 23, 3, p. 316-323 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
2017

2016 updated MASCC/ESMO consensus recommendations: prevention of nausea and vomiting following multiple-day chemotherapy, high-dose chemotherapy, and breakthrough nausea and vomiting

Einhorn, L. H., Rapoport, B., Navari, R. M., Herrstedt, J. & Brames, M. J., Jan 1 2017, In : Supportive Care in Cancer. 25, 1, p. 303-308 6 p.

Research output: Contribution to journalArticle

33 Scopus citations

Can radiotherapy potentiate the effectiveness of immune checkpoint inhibitors in lung cancer?

Cheng, M., Durm, G., Hanna, N., Einhorn, L. H. & Kong, F. M., Dec 2017, In : Future Oncology. 13, 28, p. 2503-2505 3 p.

Research output: Contribution to journalEditorial

5 Scopus citations
8 Scopus citations

Clinical and genome-wide analysis of cisplatin-induced peripheral neuropathy in survivors of adult-onset cancer

Dolan, M. E., Charif, O. E., Wheeler, H. E., Gamazon, E. R., Ardeshir-Rouhani-fard, S., Monahan, P., Feldman, D. R., Hamilton, R. J., Vaughn, D. J., Beard, C. J., Fung, C., Kim, J., Fossa, S. D., Hertz, D. L., Mushiroda, T., Kubo, M., Einhorn, L. H., Cox, N. J. & Travis, L. B., Oct 1 2017, In : Clinical Cancer Research. 23, 19, p. 5757-5768 12 p.

Research output: Contribution to journalArticle

22 Scopus citations
51 Scopus citations

Long-term toxicity of cisplatin in germ-cell tumor survivors

Chovanec, M., Abu Zaid, M., Hanna, N., El-Kouri, N., Einhorn, L. H. & Albany, C., Jan 1 2017, In : Annals of Oncology. 28, 11, p. 2670-2679 10 p.

Research output: Contribution to journalReview article

40 Scopus citations

Love in the time of cancer

Einhorn, L. H., Oct 20 2017, In : Journal of Clinical Oncology. 35, 30, p. 3482-3483 2 p.

Research output: Contribution to journalShort survey

Multi-institutional assessment of adverse health outcomes among north American testicular cancer survivors after modern cisplatin-based chemotherapy

Platinum Study Group, Apr 10 2017, In : Journal of Clinical Oncology. 35, 11, p. 1211-1222 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

Phase i Study of Amrubicin and Cyclophosphamide in Patients with Advanced Solid Organ Malignancies

Jalal, S. I., Hanna, N., Zon, R., Masters, G. A., Borghaei, H., Koneru, K., Badve, S., Prasad, N., Somaiah, N., Wu, J., Yu, Z. & Einhorn, L., Jan 1 2017, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 40, 4, p. 329-335 7 p.

Research output: Contribution to journalArticle

Refractory testicular germ cell tumors are highly sensitive to the second generation DNA methylation inhibitor guadecitabine

Albany, C., Hever-Jardine, M. P., von Herrmann, K. M., Yim, C. Y., Tam, J., Warzecha, J. M., Shin, L., Bock, S. E., Curran, B. S., Chaudhry, A. S., Kim, F., Sandusky, G. E., Taverna, P., Freemantle, S. J., Christensen, B. C., Einhorn, L. H. & Spinella, M. J., Jan 1 2017, In : Oncotarget. 8, 2, p. 2949-2959 11 p.

Research output: Contribution to journalArticle

31 Scopus citations

Salvage therapy for relapsed testicular cancer

Adra, N. & Einhorn, L. H., Jan 1 2017, In : Oncotarget. 8, 45, p. 78253-78254 2 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Salvage therapy for relapsed testicular cancer

Adra, N. & Einhorn, L. H., Jan 1 2017, In : Oncotarget. 8, 41, p. 69200-69201 2 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Testicular cancer: The usage of central review for pathology diagnosis of orchiectomy specimens

Harari, S. E., Sassoon, D. J., Priemer, D. S., Jacob, J. M., Eble, J. N., Caliò, A., Grignon, D. J., Idrees, M., Albany, C., Masterson, T. A., Hanna, N. H., Foster, R. S., Ulbright, T. M., Einhorn, L. H. & Cheng, L., Oct 2017, In : Urologic Oncology: Seminars and Original Investigations. 35, 10, p. 605.e9-605.e16

Research output: Contribution to journalArticle

6 Scopus citations

Testicular cancer update

Adra, N. & Einhorn, L. H., May 2017, In : Clinical Advances in Hematology and Oncology. 15, 5, p. 386-396 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Variants in WFS1 and other mendelian deafness genes are associated with cisplatin-associated ototoxicity

Wheeler, H. E., Gamazon, E. R., Frisina, R. D., Perez-Cervantes, C., Charif, O. E., Mapes, B., Fossa, S. D., Feldman, D. R., Hamilton, R. J., Vaughn, D. J., Beard, C. J., Fung, C., Kollmannsberger, C., Kim, J., Mushiroda, T., Kubo, M., Ardeshir-Rouhani-Fard, S., Einhorn, L. H., Cox, N. J., Dolan, M. E. & 1 others, Travis, L. B., Jul 1 2017, In : Clinical Cancer Research. 23, 13, p. 3325-3333 9 p.

Research output: Contribution to journalArticle

27 Scopus citations
2016

2016 MASCC and ESMO guideline update for the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting and of nausea and vomiting in advanced cancer patients

Roila, F., Molassiotis, A., Herrstedt, J., Aapro, M., Gralla, R. J., Bruera, E., Clark-Snow, R. A., Dupuis, L. L., Einhorn, L. H., Feyer, P., Hesketh, P. J., Jordan, K., Olver, I., Rapoport, B. L., Roscoe, J., Ruhlmann, C. H., Walsh, D., Warr, D., van der Wetering, M. & on behalf of the participants of the MASCC/ESMO Consensus Conference Copenhagen, B. O. T. P. O. T. MASCCESMO. C. C. C., Jan 1 2016, In : Annals of Oncology. 27, p. v119-v133

Research output: Contribution to journalArticle

192 Scopus citations

A Suggested Prognostic Reclassification of Intermediate and Poor-Risk Nonseminomatous Germ Cell Tumors

Necchi, A., Pond, G. R., Nicolai, N., Giannatempo, P., Raggi, D., Adra, N., Hanna, N., Salvioni, R., Einhorn, L. & Albany, C., May 26 2016, (Accepted/In press) In : Clinical Genitourinary Cancer.

Research output: Contribution to journalArticle

9 Scopus citations

Brain metastases in patients with germ cell tumors: Prognostic factors and treatment options - An analysis from the Global Germ Cell Cancer Group

Feldman, D. R., Lorch, A., Kramar, A., Albany, C., Einhorn, L., Giannatempo, P., Necchi, A., Flechon, A., Boyle, H., Chung, P., Huddart, R. A., Bokemeyer, C., Tryakin, A., Sava, T., Winquist, E. W., De Giorgi, U., Aparicio, J., Sweeney, C. J., Cedermark, G. C., Beyer, J. & 1 others, Powles, T., Feb 1 2016, In : Journal of Clinical Oncology. 34, 4, p. 345-351 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

Chemotherapy-related chronic myelogenous leukemia: A case series of patients with germ cell tumor

Adra, N., Sayar, H. & Einhorn, L. H., Mar 2016, In : JAMA Oncology. 2, 3, p. 391-392 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

Clinical benefit of a precision medicine based approach for guiding treatment of refractory cancers

Radovich, M., Kiel, P. J., Nance, S. M., Niland, E. E., Parsley, M. E., Ferguson, M. E., Jiang, G., Ammakkanavar, N. R., Einhorn, L. H., Cheng, L., Nassiri, M., Davidson, D. D., Rushing, D. A., Loehrer, P. J., Pili, R., Hanna, N., Thomas Callaghan, J., Skaar, T. C., Helft, P. R., Shahda, S. & 2 others, O'Neil, B. H. & Schneider, B. P., Jan 1 2016, In : Oncotarget. 7, 35, p. 56491-56500 10 p.

Research output: Contribution to journalArticle

37 Scopus citations

Comprehensive audiometric analysis of hearing impairment and tinnitus after cisplatin-based chemotherapy in survivors of adult-onset cancer

Frisina, R. D., Wheeler, H. E., Fossa, S. D., Kerns, S. L., Fung, C., Sesso, H. D., Monahan, P. O., Feldman, D. R., Hamilton, R., Vaughn, D. J., Beard, C. J., Budnick, A., Johnson, E. M., Ardeshir-Rouhani-fard, S., Einhorn, L. H., Lipshultz, S. E., Dolan, M. E. & Travis, L. B., Aug 10 2016, In : Journal of Clinical Oncology. 34, 23, p. 2712-2720 9 p.

Research output: Contribution to journalArticle

65 Scopus citations

Management of stage I testicular germ cell tumours

Chovanec, M., Hanna, N., Cary, K. C., Einhorn, L. & Albany, C., Nov 1 2016, In : Nature Reviews Urology. 13, 11, p. 663-673 11 p.

Research output: Contribution to journalReview article

27 Scopus citations

Perioperative morbidity and mortality associated with bleomycin in primary mediastinal nonseminomatous germ cell tumor

Ranganath, P., Kesler, K. & Einhorn, L., Dec 20 2016, In : Journal of Clinical Oncology. 34, 36, p. 4445-4446 2 p.

Research output: Contribution to journalLetter

10 Scopus citations

Phase II study of fosaprepitant + 5HT3 receptor antagonist + dexamethasone in patients with germ cell tumors undergoing 5-day cisplatin-based chemotherapy: a Hoosier Cancer Research Network study

Adra, N., Albany, C., Brames, M. J., Case-Eads, S., Johnson, C. S., Liu, Z., Fausel, C. A., Breen, T., Hanna, N. H., Hauke, R. J., Picus, J. & Einhorn, L. H., Jul 1 2016, In : Supportive Care in Cancer. 24, 7, p. 2837-2842 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Prognostic factors in patients with poor-risk germ-cell tumors: A retrospective analysis of the Indiana University experience from 1990 to 2014

Adra, N., Althouse, S. K., Liu, H., Brames, M. J., Hanna, N. H., Einhorn, L. H. & Albany, C., May 1 2016, In : Annals of Oncology. 27, 5, p. 875-879 5 p., 10.1093/annonc/mdw052.

Research output: Contribution to journalArticle

21 Scopus citations
23 Scopus citations