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2020

Effect of metabolic syndrome on mean pulmonary arterial pressures in patients with acute pulmonary embolism treated with catheter-directed thrombolysis

Stewart, L. K., Beam, D. M., Casciani, T., Cameron, S. J. & Kline, J. A., Mar 1 2020, In : International Journal of Cardiology. 302, p. 138-142 5 p.

Research output: Contribution to journalArticle

Pulmonary Embolism
Arterial Pressure
Catheters
Lung
Fibrinolysis

Inhaled nitric oxide to control platelet hyper-reactivity in patients with acute submassive pulmonary embolism

Kline, J. A., Puskarich, M. A., Pike, J. W., Zagorski, J. & Alves, N. J., Mar 1 2020, In : Nitric Oxide - Biology and Chemistry. 96, p. 20-28 9 p.

Research output: Contribution to journalArticle

Platelets
Pulmonary Embolism
Nitric Oxide
Blood Platelets
Thrombelastography

Metabolic syndrome increases risk of venous thromboembolism recurrence after acute deep vein thrombosis

Stewart, L. K. & Kline, J. A., Jan 14 2020, In : Blood Advances. 4, 1, p. 127-135 9 p.

Research output: Contribution to journalArticle

Open Access
Venous Thromboembolism
Venous Thrombosis
Recurrence
Hyperlipidemias
Logistic Models

Over-Testing for Suspected Pulmonary Embolism in American Emergency Departments: The Continuing Epidemic

Kline, J. A., Garrett, J. S., Sarmiento, E. J., Strachan, C. C. & Courtney, D. M., Jan 1 2020, In : Circulation. Cardiovascular quality and outcomes. 13, 1, p. e005753

Research output: Contribution to journalArticle

Open Access
Pulmonary Embolism
Hospital Emergency Service
Angiography
Lung
Electronic Health Records
2019
9 Citations (Scopus)

Association Between Elevated Mean Arterial Blood Pressure and Neurologic Outcome After Resuscitation From Cardiac Arrest: Results From a Multicenter Prospective Cohort Study

Roberts, B. W., Kilgannon, J. H., Hunter, B., Puskarich, M. A., Shea, L., Donnino, M., Jones, C., Fuller, B. M., Kline, J., Jones, A. E., Shapiro, N. I., Abella, B. S. & Trzeciak, S., Jan 1 2019, In : Critical Care Medicine. 47, 1, p. 93-100 8 p.

Research output: Contribution to journalArticle

Heart Arrest
Resuscitation
Nervous System
Arterial Pressure
Cohort Studies

Coming in Warm: Qualitative Study and Concept Map to Cultivate Patient-centered Empathy in Emergency Care

Pettit, K. E., Rattray, N. A., Wang, H., Stuckey, S., Mark Courtney, D., Messman, A. M. & Kline, J., Jan 1 2019, In : AEM Education and Training.

Research output: Contribution to journalArticle

Emergency Medical Services
empathy
physician
Focus Groups
Physicians
1 Citation (Scopus)

Controlled clinical trial of canine therapy versus usual care to reduce patient anxiety in the emergency department

Kline, J., Fisher, M. A., Pettit, K. L., Linville, C. T. & Beck, A. M., Jan 1 2019, In : PLoS One. 14, 1, e0209232.

Research output: Contribution to journalArticle

Controlled Clinical Trials
anxiety
Canidae
Hospital Emergency Service
clinical trials
1 Citation (Scopus)

Defining the Problem—and the Solutions—to Our Stubborn Challenge of Gender Equity

Choo, E. K., Kline, J. & Abbuhl, S., Mar 1 2019, In : Academic Emergency Medicine. 26, 3, p. 279-280 2 p.

Research output: Contribution to journalEditorial

1 Citation (Scopus)

Inhaled nitric oxide to treat intermediate risk pulmonary embolism: A multicenter randomized controlled trial

Kline, J., Puskarich, M. A., Jones, A. E., Mastouri, R., Hall, C. L., Perkins, A., Gundert, E. E. & Lahm, T., Mar 1 2019, In : Nitric Oxide - Biology and Chemistry. 84, p. 60-68 9 p.

Research output: Contribution to journalArticle

Echocardiography
Pulmonary Embolism
Nitric Oxide
Randomized Controlled Trials
Oxygen
4 Citations (Scopus)

Partial pressure of arterial carbon dioxide after resuscitation from cardiac arrest and neurological outcome: A prospective multi-center protocol-directed cohort study

Hope Kilgannon, J., Hunter, B., Puskarich, M. A., Shea, L., Fuller, B. M., Jones, C., Donnino, M., Kline, J., Jones, A. E., Shapiro, N. I., Abella, B. S., Trzeciak, S. & Roberts, B. W., Jan 1 2019, (Accepted/In press) In : Resuscitation.

Research output: Contribution to journalArticle

Partial Pressure
Heart Arrest
Carbon Dioxide
Resuscitation
Cohort Studies

Positive and Negative Influences on Female First Authorship Emergency Medicine Research

Siddle, J. P., Ryckman, S. N., Hobgood, C. & Kline, J., Mar 1 2019, In : Academic Emergency Medicine. 26, 3, p. 327-330 4 p.

Research output: Contribution to journalLetter

Authorship
Emergency Medicine
Research

Replication of an emergency department-based recovery coaching intervention and pilot testing of pragmatic trial protocols within the context of Indiana's Opioid State Targeted Response plan

Watson, D. P., Brucker, K., McGuire, A., Snow-Hill, N. L., Xu, H., Cohen, A., Campbell, M., Robison, L., Sightes, E., Buhner, R., O'Donnell, D. & Kline, J., Jan 1 2019, In : Journal of Substance Abuse Treatment.

Research output: Contribution to journalArticle

Pragmatic Clinical Trials
Clinical Protocols
Opioid Analgesics
Hospital Emergency Service
Aptitude

The conference effect: National surgery meetings are associated with increased mortality at trauma centers without American College of Surgeons verification

Jenkins, P. C., Painter, S., Bell, T. M., Kline, J. & Zarzaur, B. L., Mar 1 2019, In : PLoS ONE. 14, 3, e0214020.

Research output: Contribution to journalArticle

Open Access
Trauma Centers
Surgery
surgery
Mortality
Wounds and Injuries
2018
14 Citations (Scopus)

American Society of Hematology 2018 guidelines for management of venous thromboembolism: diagnosis of venous thromboembolism

Lim, W., Le Gal, G., Bates, S. M., Righini, M., Haramati, L. B., Lang, E., Kline, J., Chasteen, S., Snyder, M., Patel, P., Bhatt, M., Patel, P., Braun, C., Begum, H., Wiercioch, W., Schünemann, H. J. & Mustafa, R. A., Nov 27 2018, In : Blood advances. 2, 22, p. 3226-3256 31 p.

Research output: Contribution to journalReview article

Venous Thromboembolism
Guidelines
Upper Extremity Deep Vein Thrombosis
Pulmonary Embolism
Venous Thrombosis
2 Citations (Scopus)
Chest Pain
Hospital Emergency Service
Anxiety
Acute Coronary Syndrome
Delphi Technique
4 Citations (Scopus)

Anxiety Associated With Increased Risk for Emergency Department Recidivism in Patients With Low-Risk Chest Pain

Musey, P., Patel, R., Fry, C., Jimenez, G., Koene, R. & Kline, J., Jan 1 2018, (Accepted/In press) In : American Journal of Cardiology.

Research output: Contribution to journalArticle

Chest Pain
Hospital Emergency Service
Anxiety
Depression
Recurrence
2 Citations (Scopus)

Assessing Risk of Future Suicidality in Emergency Department Patients

Brucker, K., Duggan, C., Niezer, J., Roseberry, K., Le-Niculescu, H., Niculescu, A. & Kline, J., Jan 1 2018, (Accepted/In press) In : Academic Emergency Medicine.

Research output: Contribution to journalArticle

Hospital Emergency Service
Suicide
Triage
Confidence Intervals
Physicians
19 Citations (Scopus)

Assessment of right ventricular function in the research setting: Knowledge gaps and pathways forward an official American thoracic society research statement

Lahm, T., Douglas, I. S., Archer, S. L., Bogaard, H. J., Chesler, N. C., Haddad, F., Hemnes, A. R., Kawut, S. M., Kline, J. A., Kolb, T. M., Mathai, S. C., Mercier, O., Michelakis, E. D., Naeije, R., Tuder, R. M., Ventetuolo, C. E., Vieillard-Baron, A., Voelkel, N. F., Vonk-Noordegraaf, A. & Hassoun, P. M., Aug 15 2018, In : American Journal of Respiratory and Critical Care Medicine. 198, 4, p. e15-e43

Research output: Contribution to journalReview article

Right Ventricular Function
Thorax
Research
Pulmonary Circulation
Patient Rights
33 Citations (Scopus)

Association Between Early Hyperoxia Exposure After Resuscitation From Cardiac Arrest and Neurological Disability: Prospective Multicenter Protocol-Directed Cohort Study

Roberts, B. W., Kilgannon, J. H., Hunter, B., Puskarich, M. A., Pierce, L., Donnino, M., Leary, M., Kline, J., Jones, A. E., Shapiro, N. I., Abella, B. S. & Trzeciak, S., May 15 2018, In : Circulation. 137, 20, p. 2114-2124 11 p.

Research output: Contribution to journalArticle

Hyperoxia
Heart Arrest
Resuscitation
Cohort Studies
Confidence Intervals
6 Citations (Scopus)

Association between emergency physician self-reported empathy and patient satisfaction

Wang, H., Kline, J., Jackson, B. E., Laureano-Phillips, J., Robinson, R. D., Cowden, C. D., d’Etienne, J. P., Arze, S. E. & Zenarosa, N. R., Sep 1 2018, In : PLoS One. 13, 9, e0204113.

Research output: Contribution to journalArticle

Patient Satisfaction
physicians
Medicine
Emergencies
Physicians
5 Citations (Scopus)
Vitamin K
Intracranial Hemorrhages
Integrated Delivery of Health Care
Factor Xa
Thromboembolism

Dedication

Cloutier, R. L., Fernandez, R. & Kline, J. A., Feb 1 2018, In : Academic Emergency Medicine. 25, 2, 1 p.

Research output: Contribution to journalComment/debate

Anniversaries and Special Events
2 Citations (Scopus)

Diclofenac for reversal of right ventricular dysfunction in acute normotensive pulmonary embolism: A pilot study

Jimenez, D., Nieto, R., Corres, J., Fernández-Golfín, C., Barrios, D., Morillo, R., Quezada, C. A., Huisman, M., Yusen, R. D. & Kline, J., Feb 1 2018, In : Thrombosis Research. 162, p. 1-6 6 p.

Research output: Contribution to journalArticle

Right Ventricular Dysfunction
Diclofenac
Pulmonary Embolism
Placebos
Confidence Intervals
3 Citations (Scopus)

Discrepancy Between Clinician Gestalt and Subjective Component of the Wells Score in the Evaluation of Pulmonary Embolism

Akhter, M., Kline, J., Kannan, V., Courtney, D. M. & Kabrhel, C., Jun 1 2018, In : Annals of Emergency Medicine. 71, 6, p. 796-798 3 p.

Research output: Contribution to journalLetter

Pulmonary Embolism
2 Citations (Scopus)

Effectiveness of a Decision Aid in Potentially Vulnerable Patients: A Secondary Analysis of the Chest Pain Choice Multicenter Randomized Trial

Rising, K. L., Hollander, J. E., Schaffer, J., Kline, J., Torres, C. A., Diercks, D. B., Jones, R., Owen, K. P., Meisel, Z. F., Demers, M., Leblanc, A., Shah, N. D., Inselman, J., Herrin, J., Montori, V. M. & Hess, E. P., Jan 1 2018, In : Medical Decision Making. 38, 1, p. 69-78 10 p.

Research output: Contribution to journalArticle

Decision Support Techniques
Chest Pain
Multicenter Studies
Health Literacy
Education

Effect of an educational intervention on medical student scripting and patient satisfaction: A randomized trial

Pettit, K. E., Turner, J., Pollard, K. A., Buente, B. B., Humbert, A., Perkins, A. J., Hobgood, C. & Kline, J., May 1 2018, In : Western Journal of Emergency Medicine. 19, 3, p. 585-592 8 p.

Research output: Contribution to journalArticle

Patient Satisfaction
Medical Students
Communication
Hospital Emergency Service
Control Groups
2 Citations (Scopus)

Effect of Levocarnitine vs Placebo as an Adjunctive Treatment for Septic Shock: The Rapid Administration of Carnitine in Sepsis (RACE) Randomized Clinical Trial

Jones, A. E., Puskarich, M. A., Shapiro, N. I., Guirgis, F. W., Runyon, M., Adams, J. Y., Sherwin, R., Arnold, R., Roberts, B. W., Kurz, M. C., Wang, H. E., Kline, J., Courtney, D. M., Trzeciak, S., Sterling, S. A., Nandi, U., Patki, D. & Viele, K., Dec 7 2018, In : JAMA network open. 1, 8, p. e186076

Research output: Contribution to journalArticle

Open Access
Carnitine
Septic Shock
Sepsis
Randomized Controlled Trials
Placebos
4 Citations (Scopus)

Emergency Department Discharge of Pulmonary Embolus Patients

Frank Peacock, W., Coleman, C. I., Diercks, D. B., Francis, S., Kabrhel, C., Keay, C., Kline, J., Manteuffel, J., Wildgoose, P., Xiang, J. & Singer, A. J., Sep 1 2018, In : Academic Emergency Medicine. 25, 9, p. 995-1003 9 p.

Research output: Contribution to journalArticle

Standard of Care
Embolism
Hospital Emergency Service
Lung
Pulmonary Embolism

Evaluation of the pulmonary embolism rule out criteria (PERC rule) in children evaluated for suspected pulmonary embolism

Kline, J., Ellison, A. M., Kanis, J., Pike, J. W. & Hall, C. L., Aug 1 2018, In : Thrombosis Research. 168, p. 1-4 4 p.

Research output: Contribution to journalArticle

Pulmonary Embolism
Validation Studies
Routine Diagnostic Tests
ROC Curve
Venous Thrombosis

Old Docs, New Clicks: The ConCert Examination and the Aging Emergency Physician

Burton, J. H. & Kline, J. A., Aug 2018, In : Academic Emergency Medicine. 25, 8, p. 966-968 3 p.

Research output: Contribution to journalComment/debate

Emergencies
Physicians

Ruling out pulmonary embolism in patients with high pretest probability

Akhter, M., Kline, J., Bhattarai, B., Courtney, M. & Kabrhel, C., May 1 2018, In : Western Journal of Emergency Medicine. 19, 3, p. 487-493 7 p.

Research output: Contribution to journalArticle

Pulmonary Embolism
Lung
Venous Thrombosis
Hospital Emergency Service
Observational Studies
6 Citations (Scopus)

Systematic Review and Meta-analysis of Outcomes of Patients With Subsegmental Pulmonary Embolism With and Without Anticoagulation Treatment

Bariteau, A., Stewart, L. K., Emmett, T. W. & Kline, J., Jan 1 2018, (Accepted/In press) In : Academic Emergency Medicine.

Research output: Contribution to journalArticle

Pulmonary Embolism
Meta-Analysis
Confidence Intervals
Venous Thromboembolism
Publication Bias
1 Citation (Scopus)

The effect of vertical split-flow patient management on emergency department throughput and efficiency

Garrett, J. S., Berry, C., Wong, H., Qin, H. & Kline, J., Jan 1 2018, (Accepted/In press) In : American Journal of Emergency Medicine.

Research output: Contribution to journalArticle

Hospital Emergency Service
Patient Satisfaction
Patient Acuity
Cohort Studies
Regression Analysis
1 Citation (Scopus)
Fibrin Fibrinogen Degradation Products
Decision Support Techniques
Pulmonary Embolism
Hospital Emergency Service
1 Citation (Scopus)

Validation of the STA-Liatest DDi assay for exclusion of proximal deep vein thrombosis according to the latest Clinical and Laboratory Standards Institute/Food and Drug Administration guideline: Results of a multicenter management study

Aguilar, C., Sartori, M., D'Angelo, A., Kabrhel, C., Groce, J., De Maistre, E., Wasan, S. M., Kassis, J., Lazarchick, J., Kaide, C., Vera, P. M., Kline, J., Courtney, D. M., Rubin, A., Sharafuddin, M. & Pernod, G., Jan 1 2018, In : Blood Coagulation and Fibrinolysis. 29, 6, p. 562-566 5 p.

Research output: Contribution to journalArticle

United States Food and Drug Administration
Venous Thrombosis
Multicenter Studies
Guidelines
Venous Thromboembolism
2017
5 Citations (Scopus)

Chronic Embolic Pulmonary Hypertension Caused by Pulmonary Embolism and Vascular Endothelial Growth Factor Inhibition

Neto-Neves, E. M., Brown, M. B., Zaretskaia, M. V., Rezania, S., Goodwill, A. G., McCarthy, B. P., Persohn, S. A., Territo, P. & Kline, J., Apr 1 2017, In : American Journal of Pathology. 187, 4, p. 700-712 13 p.

Research output: Contribution to journalArticle

Pulmonary Embolism
Microspheres
Pulmonary Hypertension
Vascular Endothelial Growth Factor A
Polystyrenes
3 Citations (Scopus)

Clinical characteristics of children evaluated for suspected pulmonary embolism with D-dimer testing

Kanis, J., Pike, J., Hall, C. L. & Kline, J., Nov 8 2017, (Accepted/In press) In : Archives of Disease in Childhood.

Research output: Contribution to journalArticle

Pulmonary Embolism
fibrin fragment D
Databases
Radiology
Oximetry
2 Citations (Scopus)

Comparison of acute and convalescent biomarkers of inflammation in patients with acute pulmonary embolism treated with systemic fibrinolysis vs. placebo

Stewart, L. K., Nordenholz, K. E., Courtney, M., Kabrhel, C., Jones, A. E., Rondina, M. T., Diercks, D. B., Klinger, J. R. & Kline, J., Dec 1 2017, In : Blood Coagulation and Fibrinolysis. 28, 8, p. 675-680 6 p.

Research output: Contribution to journalArticle

Fibrinolysis
Pulmonary Embolism
Biomarkers
Placebos
Inflammation
3 Citations (Scopus)

Diagnostic accuracy of the D-dimer in children

Kanis, J., Hall, C. L., Pike, J. & Kline, J., Nov 8 2017, (Accepted/In press) In : Archives of Disease in Childhood.

Research output: Contribution to journalArticle

Pulmonary Embolism
Venous Thrombosis
fibrin fragment D
Electronic Health Records
Emergency Medical Services
2 Citations (Scopus)
Acute Coronary Syndrome
Hospital Emergency Service
Confidence Intervals
Costs and Cost Analysis
Thorax
1 Citation (Scopus)

Emergency Physicians Are Able to Detect Right Ventricular Dilation With Good Agreement Compared to Cardiology

Rutz, M. A., Clary, J. M., Kline, J. & Russell, F., Jul 1 2017, In : Academic Emergency Medicine. 24, 7, p. 867-874 8 p.

Research output: Contribution to journalArticle

Cardiology
Dilatation
Emergencies
Physicians
Dyspnea
16 Citations (Scopus)

High-intensity interval training, but not continuous training, reverses right ventricular hypertrophy and dysfunction in a rat model of pulmonary hypertension

Brown, M. B., Neves, E., Long, G., Graber, J., Gladish, B., Wiseman, A., Owens, M., Fisher, A. J., Presson, R., Petrache, I., Kline, J. & Lahm, T., 2017, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 312, 2, p. R197-R210

Research output: Contribution to journalArticle

Right Ventricular Dysfunction
Right Ventricular Hypertrophy
Pulmonary Hypertension
Heart Ventricles
Lung
Right Ventricular Dysfunction
Angiography
Hospital Emergency Service
Lung
Pulmonary Hypertension
3 Citations (Scopus)

Impact of a Shared Decision Making Intervention on Health Care Utilization: A Secondary Analysis of the Chest Pain Choice Multicenter Randomized Trial

Schaffer, J., Hess, E. P., Hollander, J. E., Kline, J., Torres, C. A., Diercks, D. B., Jones, R., Owen, K. P., Meisel, Z. F., Demers, M., Leblanc, A., Inselman, J., Herrin, J., Montori, V. M. & Shah, N. D., Jan 1 2017, (Accepted/In press) In : Academic Emergency Medicine.

Research output: Contribution to journalArticle

Patient Acceptance of Health Care
Chest Pain
Multicenter Studies
Decision Making
Hospital Emergency Service
1 Citation (Scopus)

Impact of Patient Affect on Physician Estimate of Probability of Serious Illness and Test Ordering

Kline, J., Neumann, D., Raad, S., Schriger, D. L., Hall, C. L., Capito, J. & Kammer, D., Apr 11 2017, (Accepted/In press) In : Academic Medicine.

Research output: Contribution to journalArticle

Emergencies
illness
video
physician
Physicians
1 Citation (Scopus)

Implementation and Preliminary Clinical Outcomes of a Pharmacist-managed Venous Thromboembolism Clinic for Patients Treated With Rivaroxaban Post Emergency Department Discharge

Direnzo, B. M., Beam, D., Kline, J., Deodhar, K. S., Weber, Z. A., Davis, C. M. & Walroth, T. A., Jan 1 2017, (Accepted/In press) In : Academic Emergency Medicine.

Research output: Contribution to journalArticle

Venous Thromboembolism
Pharmacists
Hospital Emergency Service
Primary Health Care
Medication Adherence
3 Citations (Scopus)

Improving perceptions of empathy in patients undergoing low-yield computerized tomographic imaging in the emergency department

Lin, M. P., Probst, M. A., Puskarich, M. A., Dehon, E., Kuehl, D. R., Wang, R. C., Hess, E. P., Butler, K., Runyon, M. S., Wang, H., Courtney, D. M., Muckley, B., Hobgood, C., Hall, C. L. & Kline, J., Jan 1 2017, (Accepted/In press) In : Patient Education and Counseling.

Research output: Contribution to journalArticle

Hospital Emergency Service
Physicians
Radiation Injuries
Patient Preference
Vital Signs
6 Citations (Scopus)
Ventricular Pressure
Pulmonary Hypertension
Heart Ventricles
Right Ventricular Function
Blood Pressure
29 Citations (Scopus)
Right Ventricular Dysfunction
Pulmonary Embolism
Meta-Analysis
Quality of Life
Exercise
4 Citations (Scopus)

Platelet hyperactivation, apoptosis and hypercoagulability in patients with acute pulmonary embolism

Rezania, S., Puskarich, M. A., Petrusca, D., Neto-Neves, E. M., Rondina, M. T. & Kline, J., Jul 1 2017, In : Thrombosis Research. 155, p. 106-115 10 p.

Research output: Contribution to journalArticle

Thrombophilia
Pulmonary Embolism
Blood Platelets
Apoptosis
Thrombelastography